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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GAGGUAG

Z-value: 2.41

Motif logo

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miRNA associated with seed GAGGUAG

NamemiRBASE accession
hsa-let-7a-5p
MIMAT0000062
hsa-let-7b-5p
MIMAT0000063
hsa-let-7c-5p
MIMAT0000064
hsa-let-7d-5p
MIMAT0000065
hsa-let-7e-5p
MIMAT0000066
hsa-let-7f-5p
MIMAT0000067
hsa-let-7g-5p
MIMAT0000414
hsa-let-7i-5p
MIMAT0000415
hsa-miR-98-5p
MIMAT0000096
hsa-miR-4458
MIMAT0018980
hsa-miR-4500
MIMAT0019036

Activity profile of GAGGUAG motif

Sorted Z-values of GAGGUAG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_204380919 66.68 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr18_+_21693306 50.94 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr13_-_30881621 45.76 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr5_-_131132614 43.13 ENST00000307968.7
ENST00000307954.8
FNIP1
folliculin interacting protein 1
chr19_+_56915668 34.52 ENST00000333201.9
ENST00000391778.3
ZNF583
zinc finger protein 583
chr7_+_94023873 33.94 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chrX_-_54384425 28.18 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr15_+_74833518 26.32 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chrX_+_56259316 25.32 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr15_-_45670924 25.16 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr7_-_44924939 24.75 ENST00000395699.2
PURB
purine-rich element binding protein B
chr11_+_113930291 24.64 ENST00000335953.4
ZBTB16
zinc finger and BTB domain containing 16
chr1_-_179846928 24.13 ENST00000367612.3
ENST00000609928.1
TOR1AIP2
torsin A interacting protein 2
chr2_-_37193606 23.90 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr9_+_101705893 23.67 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr20_-_48532019 22.36 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr15_+_45879321 22.32 ENST00000220531.3
ENST00000567461.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr16_+_66914264 21.64 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr5_-_172198190 21.10 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr1_-_92351769 21.01 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr6_+_71122974 20.88 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr14_-_74551172 20.68 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr2_+_70142189 19.33 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr12_+_4918342 19.26 ENST00000280684.3
ENST00000433855.1
KCNA6
potassium voltage-gated channel, shaker-related subfamily, member 6
chr2_+_189839046 19.23 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr3_-_57678772 19.03 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr20_+_49348081 18.29 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr11_+_119076745 18.16 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr5_-_159739532 17.69 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr7_+_138916231 17.69 ENST00000473989.3
ENST00000288561.8
UBN2
ubinuclein 2
chr1_-_118472216 17.50 ENST00000369443.5
GDAP2
ganglioside induced differentiation associated protein 2
chr2_-_206950781 17.36 ENST00000403263.1
INO80D
INO80 complex subunit D
chr1_+_203274639 17.35 ENST00000290551.4
BTG2
BTG family, member 2
chr12_-_42538657 17.11 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr8_+_22102626 17.07 ENST00000519237.1
ENST00000397802.4
POLR3D
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr9_-_127533519 16.98 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr12_-_111021110 16.88 ENST00000354300.3
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr17_+_36508111 16.83 ENST00000331159.5
ENST00000577233.1
SOCS7
suppressor of cytokine signaling 7
chr11_+_45868957 16.71 ENST00000443527.2
CRY2
cryptochrome 2 (photolyase-like)
chr19_-_36980455 16.60 ENST00000454319.1
ENST00000392170.2
ZNF566
zinc finger protein 566
chr1_-_207224307 16.52 ENST00000315927.4
YOD1
YOD1 deubiquitinase
chr4_+_128554081 16.49 ENST00000335251.6
ENST00000296461.5
INTU
inturned planar cell polarity protein
chr3_-_170303845 16.38 ENST00000231706.5
SLC7A14
solute carrier family 7, member 14
chr15_-_83316254 16.33 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr16_+_70148230 16.03 ENST00000398122.3
ENST00000568530.1
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr6_+_56954867 15.87 ENST00000370708.4
ENST00000370702.1
ZNF451
zinc finger protein 451
chr8_+_24772455 15.81 ENST00000433454.2
NEFM
neurofilament, medium polypeptide
chr1_+_41249539 15.51 ENST00000347132.5
ENST00000509682.2
KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr4_+_83821835 15.50 ENST00000302236.5
THAP9
THAP domain containing 9
chrX_+_16804544 15.49 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr14_+_57857262 15.46 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr19_+_4007644 15.46 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr2_+_148602058 15.43 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A
activin A receptor, type IIA
chr5_+_157170703 15.42 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr12_+_69864129 15.34 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr10_+_14920843 15.33 ENST00000433779.1
ENST00000378325.3
ENST00000354919.6
ENST00000313519.5
ENST00000420416.1
SUV39H2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr1_+_60280458 15.02 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chr1_-_153363452 14.89 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr15_-_51630772 14.85 ENST00000557858.1
ENST00000558328.1
ENST00000396404.4
ENST00000561075.1
ENST00000405011.2
ENST00000559980.1
ENST00000453807.2
ENST00000396402.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr10_-_75571341 14.85 ENST00000309979.6
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr4_-_174451370 14.82 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr17_-_61777459 14.76 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr12_-_93323013 14.70 ENST00000322349.8
EEA1
early endosome antigen 1
chr8_-_48651648 14.65 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr19_+_46800289 14.59 ENST00000377670.4
HIF3A
hypoxia inducible factor 3, alpha subunit
chr9_+_99212403 14.47 ENST00000375251.3
ENST00000375249.4
HABP4
hyaluronan binding protein 4
chr19_-_7293942 14.38 ENST00000341500.5
ENST00000302850.5
INSR
insulin receptor
chr1_+_19638788 14.17 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
PQLC2
PQ loop repeat containing 2
chr11_-_86666427 14.15 ENST00000531380.1
FZD4
frizzled family receptor 4
chr16_+_640055 13.99 ENST00000568586.1
ENST00000538492.1
ENST00000248139.3
RAB40C
RAB40C, member RAS oncogene family
chr3_+_57541975 13.97 ENST00000487257.1
ENST00000311180.8
PDE12
phosphodiesterase 12
chr3_-_53080047 13.92 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr7_-_123389104 13.81 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr17_+_29718642 13.61 ENST00000325874.8
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr19_+_45582453 13.60 ENST00000591607.1
ENST00000591747.1
ENST00000270257.4
ENST00000391951.2
ENST00000587566.1
GEMIN7
MARK4
gem (nuclear organelle) associated protein 7
MAP/microtubule affinity-regulating kinase 4
chr7_+_108210012 13.50 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_+_128848881 13.50 ENST00000259253.6
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr17_+_8213590 13.28 ENST00000361926.3
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr5_+_56111361 13.09 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr14_+_74111578 13.06 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1
dynein, axonemal, light chain 1
chr18_-_74207146 12.96 ENST00000443185.2
ZNF516
zinc finger protein 516
chr5_-_32313019 12.88 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr3_+_49591881 12.85 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr22_+_29469012 12.85 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr20_+_57267669 12.80 ENST00000356091.6
NPEPL1
aminopeptidase-like 1
chr7_+_20370746 12.72 ENST00000222573.4
ITGB8
integrin, beta 8
chr21_-_28217721 12.50 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr5_-_153857819 12.35 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr9_-_73029540 12.35 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr14_-_75593708 12.33 ENST00000557673.1
ENST00000238616.5
NEK9
NIMA-related kinase 9
chr1_-_115880852 12.21 ENST00000369512.2
NGF
nerve growth factor (beta polypeptide)
chr19_+_1752372 12.07 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr4_+_75858290 12.06 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr1_-_182573514 11.99 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr12_-_89918522 11.95 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr2_+_16080659 11.90 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr12_-_69326940 11.88 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM
carboxypeptidase M
chr11_-_72145669 11.88 ENST00000543042.1
ENST00000294053.3
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr7_-_138666053 11.88 ENST00000440172.1
ENST00000422774.1
KIAA1549
KIAA1549
chr3_+_38495333 11.84 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr17_+_64961026 11.75 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr10_+_101419187 11.74 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr2_+_177053307 11.73 ENST00000331462.4
HOXD1
homeobox D1
chr12_-_42632016 11.72 ENST00000442791.3
ENST00000327791.4
ENST00000534854.2
ENST00000380788.3
ENST00000380790.4
YAF2
YY1 associated factor 2
chr12_-_89919965 11.69 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr11_+_76571911 11.67 ENST00000534206.1
ENST00000532485.1
ENST00000526597.1
ENST00000533873.1
ENST00000538157.1
ACER3
alkaline ceramidase 3
chr5_+_65018017 11.66 ENST00000380985.5
ENST00000502464.1
NLN
neurolysin (metallopeptidase M3 family)
chr13_-_52733980 11.65 ENST00000339406.3
NEK3
NIMA-related kinase 3
chr1_+_57110972 11.61 ENST00000371244.4
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr6_+_106546808 11.59 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr8_-_134584152 11.57 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr11_-_74109422 11.54 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr14_+_24867992 11.44 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr3_-_185216766 11.34 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr14_-_52535712 11.34 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr5_+_131993856 11.21 ENST00000304506.3
IL13
interleukin 13
chr6_+_41606176 11.15 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chrX_+_21857717 11.05 ENST00000379484.5
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr6_-_35464727 11.05 ENST00000402886.3
TEAD3
TEA domain family member 3
chr17_+_77751931 11.04 ENST00000310942.4
ENST00000269399.5
CBX2
chromobox homolog 2
chr6_-_26659913 11.04 ENST00000480036.1
ENST00000415922.2
ZNF322
zinc finger protein 322
chr7_-_6312206 10.95 ENST00000350796.3
CYTH3
cytohesin 3
chr18_+_55102917 10.81 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr5_-_74326724 10.76 ENST00000322348.4
GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
chr1_-_179198702 10.71 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr4_+_88571429 10.54 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr17_-_58469474 10.53 ENST00000300896.4
USP32
ubiquitin specific peptidase 32
chr16_+_2479390 10.50 ENST00000397066.4
CCNF
cyclin F
chr1_+_113615794 10.37 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr19_+_50528971 10.30 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
ZNF473
zinc finger protein 473
chr1_-_204121013 10.29 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr7_+_76090993 10.28 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2
deltex homolog 2 (Drosophila)
chr15_-_45815005 10.27 ENST00000261867.4
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr9_-_16870704 10.25 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr16_+_81348528 10.17 ENST00000568107.2
GAN
gigaxonin
chr5_-_132948216 10.11 ENST00000265342.7
FSTL4
follistatin-like 4
chr4_+_56815102 10.09 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr10_+_115803650 10.07 ENST00000369295.2
ADRB1
adrenoceptor beta 1
chr10_-_50747064 9.98 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
ERCC6
PGBD3
ERCC6-PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr14_+_105781048 9.92 ENST00000458164.2
ENST00000447393.1
PACS2
phosphofurin acidic cluster sorting protein 2
chr12_+_103981044 9.91 ENST00000388887.2
STAB2
stabilin 2
chr5_+_176560742 9.85 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr17_-_19771216 9.84 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chrX_+_118108571 9.64 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr9_-_77567743 9.61 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr17_-_7197881 9.50 ENST00000007699.5
YBX2
Y box binding protein 2
chr1_-_9189229 9.46 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr9_+_118916082 9.42 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr8_-_82024290 9.29 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr12_+_4382917 9.28 ENST00000261254.3
CCND2
cyclin D2
chr14_-_101036119 9.12 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr5_-_139943830 9.11 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr17_-_4167142 9.06 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chrX_+_152907913 9.03 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr13_-_114144998 8.97 ENST00000332592.3
ENST00000439909.2
ENST00000375399.2
DCUN1D2
DCN1, defective in cullin neddylation 1, domain containing 2
chr3_+_50712672 8.97 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr4_+_56212270 8.95 ENST00000264228.4
SRD5A3
steroid 5 alpha-reductase 3
chr8_-_37824442 8.93 ENST00000345060.3
ADRB3
adrenoceptor beta 3
chr12_+_94542459 8.92 ENST00000258526.4
PLXNC1
plexin C1
chr1_-_169863016 8.79 ENST00000367772.4
ENST00000367771.6
SCYL3
SCY1-like 3 (S. cerevisiae)
chr9_+_102668915 8.72 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr1_-_115632035 8.63 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr19_+_47249302 8.58 ENST00000601299.1
ENST00000318584.5
ENST00000595570.1
ENST00000598271.1
ENST00000597313.1
ENST00000593875.1
ENST00000391909.3
ENST00000602250.1
ENST00000595868.1
ENST00000600629.1
ENST00000602181.1
ENST00000593800.1
ENST00000600227.1
ENST00000600005.1
ENST00000594467.1
ENST00000596460.1
FKRP
fukutin related protein
chr9_+_136325089 8.57 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1
calcium channel flower domain containing 1
chr3_+_119187785 8.52 ENST00000295588.4
ENST00000476573.1
POGLUT1
protein O-glucosyltransferase 1
chr10_+_104678032 8.51 ENST00000369878.4
ENST00000369875.3
CNNM2
cyclin M2
chr12_-_57400227 8.49 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr2_+_219575543 8.41 ENST00000457313.1
ENST00000415717.1
ENST00000392102.1
TTLL4
tubulin tyrosine ligase-like family, member 4
chr9_-_72287191 8.39 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chrX_+_147582130 8.36 ENST00000370460.2
ENST00000370457.5
AFF2
AF4/FMR2 family, member 2
chr1_+_155829286 8.27 ENST00000368324.4
SYT11
synaptotagmin XI
chr7_-_71801980 8.27 ENST00000329008.5
CALN1
calneuron 1
chr6_+_117002339 8.20 ENST00000413340.1
ENST00000368564.1
ENST00000356348.1
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr5_+_149109825 8.19 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_-_146644122 8.13 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr1_-_23857698 8.07 ENST00000361729.2
E2F2
E2F transcription factor 2
chr10_-_94003003 8.06 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr1_-_200992827 7.96 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr8_-_98290087 7.95 ENST00000322128.3
TSPYL5
TSPY-like 5
chr17_-_58603568 7.91 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr1_+_213123915 7.84 ENST00000366968.4
ENST00000490792.1
VASH2
vasohibin 2
chrX_+_49687216 7.76 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr19_+_1450112 7.71 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr8_-_93115445 7.68 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_157108130 7.67 ENST00000368192.4
ETV3
ets variant 3
chr22_-_31536480 7.60 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr1_+_12227035 7.52 ENST00000376259.3
ENST00000536782.1
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr8_+_28351707 7.51 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr12_-_102874416 7.49 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr11_-_62389449 7.39 ENST00000534026.1
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_+_138483058 7.39 ENST00000251691.4
KIAA1244
KIAA1244
chr11_-_10590238 7.39 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr10_+_102295616 7.34 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chrX_+_95939711 7.30 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr9_+_101867359 7.26 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr6_-_8064567 7.22 ENST00000543936.1
ENST00000397457.2
BLOC1S5
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr15_+_41952591 7.14 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr12_+_72666407 7.03 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr16_-_11350036 7.01 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr8_+_81397876 6.99 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10

Network of associatons between targets according to the STRING database.

First level regulatory network of GAGGUAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.9 43.8 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
7.6 45.8 GO:0051013 microtubule severing(GO:0051013)
7.4 66.7 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
7.0 28.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
7.0 21.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
6.5 19.6 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
5.6 16.7 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
5.5 16.5 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
5.4 27.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
5.3 15.8 GO:0033693 neurofilament bundle assembly(GO:0033693)
5.2 36.2 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
5.2 20.7 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
5.1 25.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
5.1 15.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
5.0 14.9 GO:2000864 negative regulation of macrophage chemotaxis(GO:0010760) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
4.8 14.4 GO:1990535 neuron projection maintenance(GO:1990535)
4.7 14.2 GO:1903401 L-lysine transmembrane transport(GO:1903401)
4.6 13.8 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
4.5 13.5 GO:0097359 UDP-glucosylation(GO:0097359)
4.2 16.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
3.9 11.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
3.7 11.2 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
3.4 10.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
3.2 19.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
3.1 15.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
3.0 24.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
3.0 21.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
3.0 9.0 GO:0016095 polyprenol catabolic process(GO:0016095)
2.8 8.3 GO:1905154 negative regulation of membrane invagination(GO:1905154)
2.7 8.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
2.7 29.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
2.7 39.8 GO:0043589 skin morphogenesis(GO:0043589)
2.6 13.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
2.6 15.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
2.5 7.5 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
2.4 7.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
2.4 12.2 GO:0032455 nerve growth factor processing(GO:0032455)
2.4 9.5 GO:0009386 translational attenuation(GO:0009386)
2.4 7.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
2.3 6.8 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
2.2 26.9 GO:0015074 DNA integration(GO:0015074)
2.2 6.7 GO:1904317 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
2.2 15.3 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
2.1 29.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) positive regulation of pigment cell differentiation(GO:0050942) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
2.1 19.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
2.1 23.1 GO:0006600 creatine metabolic process(GO:0006600)
2.1 37.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
2.1 12.5 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
2.0 4.1 GO:0046666 retinal cell programmed cell death(GO:0046666)
2.0 12.0 GO:0032345 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
1.8 11.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
1.8 7.3 GO:1905075 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.8 5.3 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
1.8 12.4 GO:0051414 response to cortisol(GO:0051414)
1.7 8.7 GO:0016240 autophagosome docking(GO:0016240)
1.7 19.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.7 8.4 GO:0035063 nuclear speck organization(GO:0035063)
1.7 13.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.6 6.4 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
1.6 9.7 GO:0032119 sequestering of zinc ion(GO:0032119)
1.6 11.0 GO:0007256 activation of JNKK activity(GO:0007256)
1.6 3.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
1.5 4.6 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
1.5 9.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
1.5 9.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.5 10.5 GO:0070166 enamel mineralization(GO:0070166)
1.5 7.5 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.5 4.5 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
1.5 11.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.4 8.6 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
1.4 9.8 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
1.4 9.8 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
1.4 5.6 GO:1990936 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
1.4 8.4 GO:0018095 protein polyglutamylation(GO:0018095)
1.4 7.0 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.4 2.8 GO:0071873 response to norepinephrine(GO:0071873)
1.3 10.8 GO:0002118 aggressive behavior(GO:0002118)
1.3 4.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.3 16.8 GO:0021819 layer formation in cerebral cortex(GO:0021819)
1.3 3.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
1.3 6.5 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
1.3 3.8 GO:1904954 Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
1.3 16.6 GO:0090435 protein localization to nuclear envelope(GO:0090435)
1.3 3.8 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.3 3.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
1.3 7.6 GO:0007288 sperm axoneme assembly(GO:0007288)
1.2 14.8 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
1.2 13.6 GO:0070314 G1 to G0 transition(GO:0070314)
1.2 1.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
1.2 8.5 GO:0048318 axial mesoderm development(GO:0048318)
1.2 3.6 GO:0031133 regulation of axon diameter(GO:0031133)
1.2 14.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.2 6.0 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.2 4.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.2 11.7 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
1.2 17.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
1.2 10.4 GO:0051045 negative regulation of axon regeneration(GO:0048681) negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.1 3.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
1.1 4.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
1.1 16.5 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
1.1 6.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.1 13.1 GO:0036158 outer dynein arm assembly(GO:0036158)
1.1 16.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.1 3.3 GO:0021571 rhombomere 5 development(GO:0021571)
1.1 6.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.1 3.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
1.1 3.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
1.1 8.4 GO:0016926 protein desumoylation(GO:0016926)
1.0 1.0 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
1.0 4.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
1.0 19.7 GO:0006853 carnitine shuttle(GO:0006853)
1.0 4.9 GO:0046477 glycosylceramide catabolic process(GO:0046477)
1.0 2.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
1.0 6.7 GO:0050893 sensory processing(GO:0050893)
0.9 2.8 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.9 8.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.9 11.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.9 4.4 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.9 3.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.9 11.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.9 7.7 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.9 11.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.8 3.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.8 12.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.8 0.8 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.8 4.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.8 11.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.8 8.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.8 7.0 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.8 8.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.8 3.1 GO:0019086 late viral transcription(GO:0019086)
0.8 12.8 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.7 3.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7 1.5 GO:1903365 regulation of fear response(GO:1903365) regulation of behavioral fear response(GO:2000822)
0.7 20.6 GO:0060674 placenta blood vessel development(GO:0060674)
0.7 11.7 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.7 4.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.7 10.2 GO:0043586 tongue development(GO:0043586)
0.7 2.2 GO:0002384 hepatic immune response(GO:0002384)
0.7 9.5 GO:0060019 radial glial cell differentiation(GO:0060019)
0.7 7.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.7 11.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.7 10.5 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.7 5.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 7.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6 10.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.6 7.5 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.6 8.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.6 3.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 1.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.6 5.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.6 5.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.6 2.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.6 5.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.6 5.7 GO:0015871 choline transport(GO:0015871)
0.5 10.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.5 6.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.5 5.9 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.5 1.6 GO:0051697 protein delipidation(GO:0051697)
0.5 4.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.5 16.8 GO:0005980 glycogen catabolic process(GO:0005980)
0.5 2.4 GO:0001555 oocyte growth(GO:0001555)
0.5 4.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.5 2.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 5.0 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5 6.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.5 10.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 9.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.4 13.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.4 14.7 GO:0097576 vacuole fusion(GO:0097576)
0.4 5.6 GO:0045008 depyrimidination(GO:0045008)
0.4 5.4 GO:0002467 germinal center formation(GO:0002467)
0.4 11.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.4 15.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.4 14.0 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.4 1.6 GO:0015853 adenine transport(GO:0015853)
0.4 12.7 GO:0007616 long-term memory(GO:0007616)
0.4 3.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.4 3.3 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.4 2.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.4 6.9 GO:0060009 Sertoli cell development(GO:0060009)
0.4 19.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.4 1.8 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 14.7 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.3 13.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.3 5.9 GO:0007159 leukocyte cell-cell adhesion(GO:0007159)
0.3 5.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 5.7 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.3 12.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.3 12.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.3 3.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 12.2 GO:0030279 negative regulation of ossification(GO:0030279)
0.3 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 14.7 GO:0030500 regulation of bone mineralization(GO:0030500)
0.3 3.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.3 5.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.3 17.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.3 12.9 GO:1901998 toxin transport(GO:1901998)
0.3 6.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 4.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.3 13.8 GO:0016266 O-glycan processing(GO:0016266)
0.3 0.5 GO:1903059 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.3 2.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 5.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3 15.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.3 10.7 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.3 5.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 1.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 7.9 GO:0019228 neuronal action potential(GO:0019228)
0.2 2.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 1.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.3 GO:0016584 nucleosome positioning(GO:0016584)
0.2 8.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 43.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2 14.7 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 3.9 GO:0070932 histone H3 deacetylation(GO:0070932)
0.2 11.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.2 1.3 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 13.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2 4.2 GO:0071711 basement membrane organization(GO:0071711)
0.2 12.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.2 4.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.2 11.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 17.5 GO:0032526 response to retinoic acid(GO:0032526)
0.2 6.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 6.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 2.0 GO:0034378 chylomicron assembly(GO:0034378)
0.2 11.2 GO:0035418 protein localization to synapse(GO:0035418)
0.2 3.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 1.4 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.2 1.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 5.3 GO:0009306 protein secretion(GO:0009306)
0.2 8.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 16.4 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 2.2 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 8.2 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.1 7.3 GO:0048477 oogenesis(GO:0048477)
0.1 0.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 1.2 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.1 9.1 GO:0016567 protein ubiquitination(GO:0016567)
0.1 2.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.3 GO:0014029 neural crest formation(GO:0014029)
0.1 1.9 GO:0030199 collagen fibril organization(GO:0030199)
0.1 8.3 GO:0030574 collagen catabolic process(GO:0030574)
0.1 5.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 9.8 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 18.5 GO:0007601 visual perception(GO:0007601)
0.1 4.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 2.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 4.1 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.1 9.1 GO:0007219 Notch signaling pathway(GO:0007219)
0.1 3.0 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 6.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 3.5 GO:0043171 peptide catabolic process(GO:0043171)
0.1 4.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 4.7 GO:0046847 filopodium assembly(GO:0046847)
0.1 2.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 6.7 GO:0007030 Golgi organization(GO:0007030)
0.1 5.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 12.8 GO:0006310 DNA recombination(GO:0006310)
0.1 1.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.8 GO:0060021 palate development(GO:0060021)
0.1 2.7 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.1 GO:1902410 unidimensional cell growth(GO:0009826) mitotic cytokinetic process(GO:1902410)
0.0 1.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 2.9 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 1.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 1.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 4.1 GO:0051726 regulation of cell cycle(GO:0051726)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 5.4 GO:0007155 cell adhesion(GO:0007155)
0.0 20.4 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 1.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 1.9 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.0 0.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.0 0.4 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.3 GO:0007416 synapse assembly(GO:0007416)
0.0 1.0 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.2 GO:0044070 regulation of anion transport(GO:0044070)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 36.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
4.2 12.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
3.9 66.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
3.9 15.5 GO:0031417 NatC complex(GO:0031417)
3.8 15.0 GO:0070695 FHF complex(GO:0070695)
3.7 44.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.9 14.7 GO:0044308 axonal spine(GO:0044308)
2.9 14.4 GO:0005899 insulin receptor complex(GO:0005899)
2.6 25.9 GO:0098651 basement membrane collagen trimer(GO:0098651)
1.9 11.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.9 15.4 GO:0005683 U7 snRNP(GO:0005683)
1.8 9.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.7 13.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.7 8.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.7 24.8 GO:0005662 DNA replication factor A complex(GO:0005662)
1.6 29.5 GO:0031083 BLOC-1 complex(GO:0031083)
1.6 13.1 GO:0036157 outer dynein arm(GO:0036157)
1.5 9.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.4 18.2 GO:0016600 flotillin complex(GO:0016600)
1.3 24.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.2 3.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.1 13.3 GO:0030425 dendrite(GO:0030425)
1.1 8.6 GO:0043196 varicosity(GO:0043196)
1.1 15.8 GO:0005883 neurofilament(GO:0005883)
1.0 20.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.0 8.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.0 7.7 GO:0016342 catenin complex(GO:0016342)
0.9 13.8 GO:0030478 actin cap(GO:0030478)
0.8 7.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.8 11.0 GO:0035102 PRC1 complex(GO:0035102)
0.8 3.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.8 2.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.8 3.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.7 9.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.7 2.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.7 17.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 1.9 GO:0005593 FACIT collagen trimer(GO:0005593)
0.6 4.3 GO:0000813 ESCRT I complex(GO:0000813)
0.6 20.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.6 14.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.6 3.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.6 1.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.6 5.0 GO:0016013 syntrophin complex(GO:0016013)
0.5 2.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 2.6 GO:0097165 nuclear stress granule(GO:0097165)
0.5 3.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.5 3.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.5 21.0 GO:0048786 presynaptic active zone(GO:0048786)
0.5 25.3 GO:0016235 aggresome(GO:0016235)
0.5 5.9 GO:0005577 fibrinogen complex(GO:0005577)
0.5 11.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 6.7 GO:0043194 axon initial segment(GO:0043194)
0.4 1.3 GO:0031213 RSF complex(GO:0031213)
0.4 3.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.4 50.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.4 8.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 2.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 3.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 8.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 43.5 GO:0016605 PML body(GO:0016605)
0.3 2.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 3.8 GO:0042575 DNA polymerase complex(GO:0042575)
0.3 1.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.3 7.9 GO:0016592 mediator complex(GO:0016592)
0.3 2.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 3.2 GO:0031045 dense core granule(GO:0031045)
0.3 3.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 6.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 37.8 GO:0005923 bicellular tight junction(GO:0005923)
0.3 23.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 18.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.3 5.4 GO:0044295 axonal growth cone(GO:0044295)
0.3 21.8 GO:0005814 centriole(GO:0005814)
0.3 8.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3 14.5 GO:0005801 cis-Golgi network(GO:0005801)
0.2 10.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 16.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 22.4 GO:0005604 basement membrane(GO:0005604)
0.2 5.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 10.3 GO:0015030 Cajal body(GO:0015030)
0.2 29.3 GO:0001650 fibrillar center(GO:0001650)
0.2 16.8 GO:0036064 ciliary basal body(GO:0036064)
0.2 2.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.2 4.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.3 GO:0030175 filopodium(GO:0030175)
0.2 15.9 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.2 20.6 GO:0005796 Golgi lumen(GO:0005796)
0.2 15.4 GO:0055037 recycling endosome(GO:0055037)
0.2 8.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 3.7 GO:0035579 specific granule membrane(GO:0035579)
0.2 6.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 11.9 GO:0008021 synaptic vesicle(GO:0008021)
0.1 4.7 GO:0031904 endosome lumen(GO:0031904)
0.1 8.0 GO:0043195 terminal bouton(GO:0043195)
0.1 4.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 9.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 2.5 GO:0005922 connexon complex(GO:0005922)
0.1 53.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 11.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 19.4 GO:0030426 growth cone(GO:0030426)
0.1 0.7 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 10.2 GO:0043209 myelin sheath(GO:0043209)
0.1 4.4 GO:0030120 vesicle coat(GO:0030120)
0.1 23.7 GO:0005769 early endosome(GO:0005769)
0.1 18.9 GO:0030027 lamellipodium(GO:0030027)
0.1 30.9 GO:0043235 receptor complex(GO:0043235)
0.1 4.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 11.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 41.9 GO:0005874 microtubule(GO:0005874)
0.1 4.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 6.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 12.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 20.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 14.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 6.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 4.4 GO:0043204 perikaryon(GO:0043204)
0.1 3.9 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 11.4 GO:0005813 centrosome(GO:0005813)
0.0 5.7 GO:0030424 axon(GO:0030424)
0.0 17.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.2 GO:0001726 ruffle(GO:0001726)
0.0 3.1 GO:0005911 cell-cell junction(GO:0005911)
0.0 4.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 25.8 GO:0005615 extracellular space(GO:0005615)
0.0 5.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 5.9 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
10.8 43.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
7.6 45.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
6.5 19.6 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
6.3 37.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
6.3 31.3 GO:0061665 SUMO ligase activity(GO:0061665)
6.2 31.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
5.5 16.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
5.1 15.4 GO:0071209 U7 snRNA binding(GO:0071209)
5.0 14.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
4.8 14.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
4.8 67.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
4.7 14.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
4.5 13.5 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
4.3 30.2 GO:0017002 activin-activated receptor activity(GO:0017002)
3.9 15.5 GO:0004803 transposase activity(GO:0004803)
3.9 11.6 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
3.7 14.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
3.6 14.4 GO:0043559 insulin binding(GO:0043559)
3.6 10.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
3.3 9.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
3.1 15.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
3.0 9.0 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
2.9 11.7 GO:0017040 ceramidase activity(GO:0017040)
2.9 8.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
2.8 28.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
2.6 28.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
2.6 28.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
2.5 12.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.2 20.0 GO:0019211 phosphatase activator activity(GO:0019211)
2.1 8.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
2.0 5.9 GO:0070052 collagen V binding(GO:0070052)
1.9 11.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.8 18.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.8 5.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.8 5.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.7 7.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
1.7 8.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.7 6.7 GO:0004992 platelet activating factor receptor activity(GO:0004992)
1.6 4.8 GO:0004924 oncostatin-M receptor activity(GO:0004924)
1.5 23.2 GO:0009881 photoreceptor activity(GO:0009881)
1.5 24.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.5 16.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
1.4 10.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.4 4.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.4 5.6 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
1.3 5.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.3 3.8 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.2 6.0 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.2 23.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.2 15.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.2 8.2 GO:0050682 AF-2 domain binding(GO:0050682)
1.1 25.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
1.1 4.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
1.1 2.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.0 7.3 GO:0071532 ankyrin repeat binding(GO:0071532)
1.0 5.2 GO:0043532 angiostatin binding(GO:0043532)
1.0 5.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.9 5.7 GO:0039552 RIG-I binding(GO:0039552)
0.9 4.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.9 21.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.9 15.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.9 11.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.9 13.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.8 19.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.8 20.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.8 14.9 GO:0070330 aromatase activity(GO:0070330)
0.8 23.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.8 11.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.8 4.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.8 3.2 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.8 3.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.8 2.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.8 12.2 GO:0005165 neurotrophin receptor binding(GO:0005165)
0.8 7.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.8 9.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 17.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.7 8.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.7 6.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.7 7.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.7 23.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.7 15.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.7 13.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 13.5 GO:0051787 misfolded protein binding(GO:0051787)
0.7 3.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 13.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.7 3.9 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.6 6.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6 14.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.6 4.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.6 4.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.5 3.8 GO:0016015 morphogen activity(GO:0016015)
0.5 10.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.5 7.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.5 57.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.5 5.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 6.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.5 4.6 GO:0045545 syndecan binding(GO:0045545)
0.5 6.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.5 3.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 7.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 3.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.4 6.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.4 4.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.4 2.6 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4 15.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.4 5.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 18.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.4 10.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 39.2 GO:0019905 syntaxin binding(GO:0019905)
0.4 10.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 1.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.4 4.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4 1.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.4 14.8 GO:0070888 E-box binding(GO:0070888)
0.4 3.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 6.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 7.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.4 7.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 62.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 19.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 10.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.4 3.2 GO:0030911 TPR domain binding(GO:0030911)
0.3 10.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 26.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.3 3.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 1.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 7.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 34.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.3 34.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.3 9.7 GO:0001671 ATPase activator activity(GO:0001671)
0.3 5.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 2.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 3.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 10.7 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.3 5.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 10.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 25.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 7.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 5.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 17.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.2 17.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2 6.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.2 11.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.2 5.0 GO:0017166 vinculin binding(GO:0017166)
0.2 3.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 6.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 6.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 2.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 3.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 11.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 3.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 57.3 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 6.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 10.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.8 GO:0035198 miRNA binding(GO:0035198)
0.2 5.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 3.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.7 GO:0070700 BMP receptor binding(GO:0070700)
0.2 3.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 4.1 GO:0005123 death receptor binding(GO:0005123)
0.1 2.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.7 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 17.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 3.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 9.0 GO:0005518 collagen binding(GO:0005518)
0.1 17.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 1.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 8.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 4.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 6.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 18.0 GO:0042393 histone binding(GO:0042393)
0.1 27.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 7.9 GO:0043130 ubiquitin binding(GO:0043130)
0.1 12.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 5.1 GO:0003777 microtubule motor activity(GO:0003777)
0.1 5.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 4.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 12.2 GO:0005126 cytokine receptor binding(GO:0005126)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.7 GO:0030332 cyclin binding(GO:0030332)
0.1 3.6 GO:0001047 core promoter binding(GO:0001047)
0.0 3.2 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 17.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 2.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.1 GO:0008047 enzyme activator activity(GO:0008047)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
1.6 75.8 NABA COLLAGENS Genes encoding collagen proteins
1.1 11.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.0 30.8 PID WNT SIGNALING PATHWAY Wnt signaling network
1.0 58.8 PID IFNG PATHWAY IFN-gamma pathway
0.9 3.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.8 34.5 PID ALK1 PATHWAY ALK1 signaling events
0.7 16.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.6 5.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 9.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.5 6.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.5 12.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 8.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 28.3 PID LKB1 PATHWAY LKB1 signaling events
0.5 12.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 13.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 20.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.4 15.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.4 19.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.4 15.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4 13.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.4 14.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.4 16.3 PID AURORA A PATHWAY Aurora A signaling
0.4 11.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 14.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 18.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.4 15.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.4 14.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4 6.8 PID REELIN PATHWAY Reelin signaling pathway
0.4 7.5 PID IGF1 PATHWAY IGF1 pathway
0.4 5.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 9.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.3 2.2 ST STAT3 PATHWAY STAT3 Pathway
0.3 3.1 ST GAQ PATHWAY G alpha q Pathway
0.3 15.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 13.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 25.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 7.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 7.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 10.3 PID ARF6 PATHWAY Arf6 signaling events
0.2 19.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 2.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 6.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 6.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 6.9 PID BMP PATHWAY BMP receptor signaling
0.1 3.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 6.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 3.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 20.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 8.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.2 PID P73PATHWAY p73 transcription factor network
0.0 7.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 10.1 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 3.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 39.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.2 37.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.6 25.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.2 20.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
1.1 22.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.1 20.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.1 4.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.0 9.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.9 5.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.9 17.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.9 25.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.8 40.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.8 12.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.8 17.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.8 20.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.7 17.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.7 11.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.7 15.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.7 8.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.6 11.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 10.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.6 16.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.6 11.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.6 35.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.5 11.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.5 9.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 11.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5 26.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 4.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.5 21.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.5 18.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.5 18.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.5 5.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.5 10.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 19.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.4 7.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 7.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 18.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.4 16.6 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.4 5.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 9.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 12.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.4 11.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.4 4.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.4 9.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 14.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 18.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.3 11.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 6.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 3.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 7.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 9.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.3 5.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 3.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 21.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 3.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 5.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 11.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 2.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 2.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 5.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 50.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.2 6.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 7.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 17.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 5.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.2 4.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 10.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 6.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 8.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 24.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 5.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 1.0 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 6.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 5.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 6.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 4.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing