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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for GCUGGUG

Z-value: 0.75

Motif logo

logo of

miRNA associated with seed GCUGGUG

NamemiRBASE accession
hsa-miR-138-5p
MIMAT0000430

Activity profile of GCUGGUG motif

Sorted Z-values of GCUGGUG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_10199468 10.83 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr19_-_49944806 7.31 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr15_-_48470558 6.95 ENST00000324324.7
MYEF2
myelin expression factor 2
chr5_-_176057365 6.77 ENST00000310112.3
SNCB
synuclein, beta
chr3_-_13009168 6.18 ENST00000273221.4
IQSEC1
IQ motif and Sec7 domain 1
chr6_-_46293378 5.99 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr17_-_78450398 5.36 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr4_+_47033345 5.23 ENST00000295454.3
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr17_-_9929581 4.71 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr1_-_41131326 4.61 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr9_+_17579084 4.22 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr11_-_123525289 3.53 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr16_-_57318566 3.52 ENST00000569059.1
ENST00000219207.5
PLLP
plasmolipin
chr6_+_107811162 3.39 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr2_+_86947296 3.35 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr20_+_54933971 3.28 ENST00000371384.3
ENST00000437418.1
FAM210B
family with sequence similarity 210, member B
chr4_-_2264015 3.27 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr1_-_20812690 3.12 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr10_+_74451883 3.10 ENST00000373053.3
ENST00000357157.6
MCU
mitochondrial calcium uniporter
chr16_+_50187556 3.08 ENST00000561678.1
ENST00000357464.3
PAPD5
PAP associated domain containing 5
chr7_+_155250824 3.08 ENST00000297375.4
EN2
engrailed homeobox 2
chr18_-_53255766 3.02 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr19_+_35521572 3.00 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr12_-_498620 3.00 ENST00000399788.2
ENST00000382815.4
KDM5A
lysine (K)-specific demethylase 5A
chr7_-_103629963 2.91 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr6_-_41909561 2.88 ENST00000372991.4
CCND3
cyclin D3
chr1_+_26856236 2.87 ENST00000374168.2
ENST00000374166.4
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr5_+_175792459 2.85 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr22_-_45636650 2.83 ENST00000336156.5
KIAA0930
KIAA0930
chr9_-_131534160 2.62 ENST00000291900.2
ZER1
zyg-11 related, cell cycle regulator
chr3_-_57678772 2.62 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr2_-_43453734 2.59 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr3_-_9291063 2.56 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr6_+_39760783 2.49 ENST00000398904.2
ENST00000538976.1
DAAM2
dishevelled associated activator of morphogenesis 2
chr3_+_47324424 2.46 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chr15_-_43877062 2.46 ENST00000381885.1
ENST00000396923.3
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr19_-_14316980 2.43 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr4_-_90229142 2.41 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr8_-_41655107 2.36 ENST00000347528.4
ENST00000289734.7
ENST00000379758.2
ENST00000396945.1
ENST00000396942.1
ENST00000352337.4
ANK1
ankyrin 1, erythrocytic
chr2_-_240322643 2.34 ENST00000345617.3
HDAC4
histone deacetylase 4
chr8_+_22462145 2.19 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
CCAR2
cell cycle and apoptosis regulator 2
chr13_+_42846272 2.18 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr9_-_130679257 2.16 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr22_+_40573921 2.16 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr2_-_182545603 2.11 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr17_-_27916621 2.10 ENST00000225394.3
GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr17_-_58603568 2.04 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr5_-_115910630 2.04 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr10_+_71078595 2.01 ENST00000359426.6
HK1
hexokinase 1
chr13_+_111365602 1.90 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr7_-_30029367 1.79 ENST00000242059.5
SCRN1
secernin 1
chr12_+_111843749 1.75 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr1_-_149889382 1.73 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr19_+_3880581 1.72 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr5_+_49961727 1.67 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8
poly (ADP-ribose) polymerase family, member 8
chr3_-_142166904 1.67 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr22_-_43583079 1.64 ENST00000216129.6
TTLL12
tubulin tyrosine ligase-like family, member 12
chr1_-_31712401 1.62 ENST00000373736.2
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr16_+_84733575 1.60 ENST00000219473.7
ENST00000563892.1
ENST00000562283.1
ENST00000570191.1
ENST00000569038.1
ENST00000570053.1
USP10
ubiquitin specific peptidase 10
chr17_-_4890919 1.57 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2
calmodulin binding transcription activator 2
chr17_-_17875688 1.57 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr17_+_38474489 1.54 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr12_+_132195617 1.52 ENST00000261674.4
ENST00000535236.1
ENST00000541286.1
SFSWAP
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr12_+_100661156 1.51 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr10_+_180987 1.50 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr16_-_29910365 1.45 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr14_-_100070363 1.44 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr10_+_104474207 1.44 ENST00000602831.1
ENST00000369893.5
SFXN2
sideroflexin 2
chr9_-_140351928 1.43 ENST00000339554.3
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr17_+_17942594 1.43 ENST00000268719.4
GID4
GID complex subunit 4
chr12_-_30848914 1.43 ENST00000256079.4
IPO8
importin 8
chr3_-_114790179 1.42 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_120517174 1.42 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr3_+_93781728 1.41 ENST00000314622.4
NSUN3
NOP2/Sun domain family, member 3
chr1_+_114472222 1.40 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr11_-_118966167 1.40 ENST00000530167.1
H2AFX
H2A histone family, member X
chr1_-_200992827 1.39 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr10_+_72164135 1.39 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr3_-_53381539 1.38 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A
decapping mRNA 1A
chr10_-_120514720 1.37 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr20_+_36149602 1.36 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr2_-_25475120 1.35 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr19_-_663277 1.35 ENST00000292363.5
RNF126
ring finger protein 126
chr6_+_34759837 1.34 ENST00000192788.5
ENST00000452449.2
UHRF1BP1
UHRF1 binding protein 1
chr19_+_13135386 1.31 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_65381643 1.30 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr5_+_140044261 1.30 ENST00000358337.5
WDR55
WD repeat domain 55
chr16_-_85722530 1.25 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr2_+_70142189 1.25 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr1_+_27719148 1.25 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr7_-_71801980 1.23 ENST00000329008.5
CALN1
calneuron 1
chr11_-_129062093 1.23 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr17_+_4710391 1.22 ENST00000263088.6
ENST00000572940.1
PLD2
phospholipase D2
chr3_-_53080047 1.22 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr17_+_54911444 1.20 ENST00000284061.3
ENST00000572810.1
DGKE
diacylglycerol kinase, epsilon 64kDa
chr15_-_75744014 1.15 ENST00000394947.3
ENST00000565264.1
SIN3A
SIN3 transcription regulator family member A
chr11_-_67980744 1.14 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr15_+_59063478 1.13 ENST00000559228.1
ENST00000450403.2
FAM63B
family with sequence similarity 63, member B
chr8_+_23104130 1.12 ENST00000313219.7
ENST00000519984.1
CHMP7
charged multivesicular body protein 7
chr7_+_90225796 1.12 ENST00000380050.3
CDK14
cyclin-dependent kinase 14
chr2_-_213403565 1.11 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr10_-_72043432 1.10 ENST00000277942.6
NPFFR1
neuropeptide FF receptor 1
chr2_-_101034070 1.09 ENST00000264249.3
CHST10
carbohydrate sulfotransferase 10
chr8_+_104831472 1.09 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr19_+_56652686 1.09 ENST00000592949.1
ZNF444
zinc finger protein 444
chr17_-_4167142 1.06 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chrX_+_21857717 1.06 ENST00000379484.5
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr2_+_10183651 1.05 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr6_+_158733692 1.05 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr19_-_1652575 1.02 ENST00000587235.1
ENST00000262965.5
TCF3
transcription factor 3
chr11_-_46142948 1.02 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr22_+_29469012 1.02 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr3_-_48700310 1.01 ENST00000164024.4
ENST00000544264.1
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3
chr12_-_54673871 1.01 ENST00000209875.4
CBX5
chromobox homolog 5
chr11_+_68228186 0.98 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3
protein phosphatase 6, regulatory subunit 3
chr11_-_45307817 0.98 ENST00000020926.3
SYT13
synaptotagmin XIII
chr16_+_58549378 0.94 ENST00000310682.2
ENST00000394266.4
ENST00000219315.4
SETD6
SET domain containing 6
chr20_-_3996036 0.94 ENST00000336095.6
RNF24
ring finger protein 24
chr4_-_140098339 0.94 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr8_+_106330920 0.94 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr17_-_43568062 0.94 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr17_-_8055747 0.94 ENST00000317276.4
ENST00000581703.1
PER1
period circadian clock 1
chr16_+_67876180 0.93 ENST00000303596.1
THAP11
THAP domain containing 11
chr10_+_102295616 0.92 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr15_-_74988281 0.90 ENST00000566828.1
ENST00000563009.1
ENST00000568176.1
ENST00000566243.1
ENST00000566219.1
ENST00000426797.3
ENST00000566119.1
ENST00000315127.4
EDC3
enhancer of mRNA decapping 3
chr6_-_111136513 0.88 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr9_-_33264676 0.87 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr19_-_2783363 0.86 ENST00000221566.2
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr11_+_131240373 0.85 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr15_+_92396920 0.84 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr12_+_69864129 0.84 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2
fibroblast growth factor receptor substrate 2
chr12_+_122516626 0.84 ENST00000319080.7
MLXIP
MLX interacting protein
chr22_+_39101728 0.84 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr13_-_107220455 0.83 ENST00000400198.3
ARGLU1
arginine and glutamate rich 1
chr5_-_74162605 0.80 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr9_-_36400213 0.80 ENST00000259605.6
ENST00000353739.4
RNF38
ring finger protein 38
chr5_-_73937244 0.78 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr12_+_20522179 0.75 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr15_+_42066632 0.73 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr16_-_70472946 0.72 ENST00000342907.2
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr17_-_39890893 0.70 ENST00000393939.2
ENST00000347901.4
ENST00000341193.5
ENST00000310778.5
HAP1
huntingtin-associated protein 1
chr9_-_37034028 0.70 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr20_-_30795511 0.70 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr11_-_78052923 0.68 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr2_+_231729615 0.67 ENST00000326427.6
ENST00000335005.6
ENST00000326407.6
ITM2C
integral membrane protein 2C
chr15_-_79237433 0.67 ENST00000220166.5
CTSH
cathepsin H
chr3_+_98451275 0.67 ENST00000265261.6
ENST00000497008.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chrX_+_9431324 0.65 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr16_-_18937726 0.64 ENST00000389467.3
ENST00000446231.2
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr2_+_208394616 0.64 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr12_-_117319236 0.64 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr19_-_344786 0.63 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr9_-_127905736 0.61 ENST00000336505.6
ENST00000373549.4
SCAI
suppressor of cancer cell invasion
chr3_-_56835967 0.61 ENST00000495373.1
ENST00000296315.3
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr6_+_136172820 0.60 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr1_+_33005020 0.59 ENST00000373510.4
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr16_+_77224732 0.59 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1B
MON1 secretory trafficking family member B
chr20_-_4982132 0.57 ENST00000338244.1
ENST00000424750.2
SLC23A2
solute carrier family 23 (ascorbic acid transporter), member 2
chr3_+_138066539 0.56 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr2_+_148602058 0.55 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A
activin A receptor, type IIA
chr8_-_20161466 0.54 ENST00000381569.1
LZTS1
leucine zipper, putative tumor suppressor 1
chr5_+_149109825 0.54 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_-_211307315 0.53 ENST00000271751.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr17_+_7608511 0.52 ENST00000226091.2
EFNB3
ephrin-B3
chr1_-_154531095 0.52 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr17_+_35294075 0.52 ENST00000254457.5
LHX1
LIM homeobox 1
chr17_-_6459768 0.51 ENST00000421306.3
PITPNM3
PITPNM family member 3
chr9_+_131709966 0.51 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr9_+_129677039 0.50 ENST00000259351.5
ENST00000424082.2
ENST00000394022.3
ENST00000394011.3
ENST00000319107.4
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr9_+_100615536 0.50 ENST00000375123.3
FOXE1
forkhead box E1 (thyroid transcription factor 2)
chr4_+_699537 0.50 ENST00000419774.1
ENST00000362003.5
ENST00000400151.2
ENST00000427463.1
ENST00000470161.2
PCGF3
polycomb group ring finger 3
chrX_+_69664706 0.48 ENST00000194900.4
ENST00000374360.3
DLG3
discs, large homolog 3 (Drosophila)
chr17_+_2240775 0.46 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr16_+_68344981 0.45 ENST00000441236.1
ENST00000348497.4
ENST00000339507.5
PRMT7
protein arginine methyltransferase 7
chr12_-_120806960 0.45 ENST00000257552.2
MSI1
musashi RNA-binding protein 1
chr19_+_30302805 0.43 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
CCNE1
cyclin E1
chr8_-_41909496 0.43 ENST00000265713.2
ENST00000406337.1
ENST00000396930.3
ENST00000485568.1
ENST00000426524.1
KAT6A
K(lysine) acetyltransferase 6A
chr11_+_33278811 0.43 ENST00000303296.4
ENST00000379016.3
HIPK3
homeodomain interacting protein kinase 3
chr9_+_115249100 0.42 ENST00000337530.6
ENST00000374244.3
ENST00000536272.1
KIAA1958
KIAA1958
chr22_+_41697520 0.42 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr13_-_72441315 0.41 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr2_-_232791038 0.41 ENST00000295440.2
ENST00000409852.1
NPPC
natriuretic peptide C
chr18_+_55102917 0.39 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr19_+_7968728 0.39 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
MAP2K7
mitogen-activated protein kinase kinase 7
chr7_-_148581251 0.39 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr10_+_76586348 0.38 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B
K(lysine) acetyltransferase 6B
chr22_+_31090793 0.38 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
OSBP2
oxysterol binding protein 2
chr14_-_27066636 0.37 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr18_-_57027194 0.37 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr6_+_41888926 0.36 ENST00000230340.4
BYSL
bystin-like
chr20_+_32077880 0.36 ENST00000342704.6
ENST00000375279.2
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr4_-_41750922 0.36 ENST00000226382.2
PHOX2B
paired-like homeobox 2b
chr5_-_176433350 0.35 ENST00000377227.4
ENST00000377219.2
UIMC1
ubiquitin interaction motif containing 1
chr6_-_31628512 0.35 ENST00000375911.1
C6orf47
chromosome 6 open reading frame 47
chr20_+_56964169 0.35 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr11_-_75062730 0.34 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr2_+_24714729 0.34 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr15_-_68521996 0.32 ENST00000418702.2
ENST00000565471.1
ENST00000564752.1
ENST00000566347.1
ENST00000249806.5
ENST00000562767.1
CLN6
RP11-315D16.2
ceroid-lipofuscinosis, neuronal 6, late infantile, variant
Uncharacterized protein
chr7_+_31092076 0.32 ENST00000304166.4
ADCYAP1R1
adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
chr1_+_20208870 0.31 ENST00000375120.3
OTUD3
OTU domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GCUGGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
2.2 10.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.0 3.0 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.9 3.4 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.7 3.0 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.6 1.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.6 1.1 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.5 5.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.5 3.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.5 3.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.5 1.4 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.4 3.1 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.4 1.7 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
0.4 4.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4 0.8 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.4 2.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.4 1.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.4 1.2 GO:0051595 response to methylglyoxal(GO:0051595)
0.4 1.9 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 0.7 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.4 3.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 3.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 2.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 0.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 0.9 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.3 0.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.3 0.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 2.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.3 5.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 2.3 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 5.2 GO:0071420 cellular response to histamine(GO:0071420)
0.3 2.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.3 3.1 GO:1990403 embryonic brain development(GO:1990403)
0.3 1.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.2 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 0.7 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.2 1.4 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.2 0.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 1.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 2.0 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.2 1.7 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.2 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 1.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.2 1.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.4 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2 0.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 1.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.2 GO:1901978 mitochondrial fragmentation involved in apoptotic process(GO:0043653) positive regulation of cell cycle checkpoint(GO:1901978)
0.2 0.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 1.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 0.9 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 6.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 2.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.6 GO:0019086 late viral transcription(GO:0019086)
0.1 5.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 3.7 GO:0097503 sialylation(GO:0097503)
0.1 1.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.4 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 1.0 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 7.1 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 2.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.4 GO:1901166 noradrenergic neuron development(GO:0003358) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.5 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.6 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 1.9 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.1 GO:0045324 viral budding via host ESCRT complex(GO:0039702) late endosome to vacuole transport(GO:0045324) ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.4 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 2.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.2 GO:0030242 pexophagy(GO:0030242)
0.1 1.6 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 0.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 2.3 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 3.5 GO:0090102 cochlea development(GO:0090102)
0.1 2.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.6 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 2.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 6.1 GO:0014902 myotube differentiation(GO:0014902)
0.1 0.7 GO:0051573 lateral ventricle development(GO:0021670) negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.3 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 1.5 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 0.8 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.2 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.7 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.7 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.7 GO:0008038 neuron recognition(GO:0008038)
0.0 1.2 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 1.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 1.8 GO:0090398 cellular senescence(GO:0090398)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 1.6 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.6 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.0 0.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.9 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 1.0 GO:0061512 protein localization to cilium(GO:0061512)
0.0 2.3 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 1.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 1.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.5 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.6 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 1.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 2.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 4.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.1 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0048026 positive regulation of circadian rhythm(GO:0042753) positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.4 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.2 7.3 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
1.1 3.4 GO:0034657 GID complex(GO:0034657)
0.8 3.1 GO:1990246 uniplex complex(GO:1990246)
0.7 2.2 GO:0044609 DBIRD complex(GO:0044609)
0.4 6.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 1.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 3.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3 1.3 GO:0000811 GINS complex(GO:0000811)
0.2 2.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 2.8 GO:0001741 XY body(GO:0001741)
0.2 7.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 5.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 3.5 GO:0043218 compact myelin(GO:0043218)
0.1 2.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.0 GO:0097440 apical dendrite(GO:0097440)
0.1 0.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.7 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 2.0 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 4.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 7.7 GO:0016234 inclusion body(GO:0016234)
0.1 2.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 3.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 3.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0098793 presynapse(GO:0098793)
0.0 3.0 GO:0030133 transport vesicle(GO:0030133)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.9 GO:0001650 fibrillar center(GO:0001650)
0.0 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0036126 sperm flagellum(GO:0036126)
0.0 7.9 GO:0030425 dendrite(GO:0030425)
0.0 1.5 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 13.4 GO:0005730 nucleolus(GO:0005730)
0.0 1.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
1.3 6.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.1 3.4 GO:0032184 SUMO polymer binding(GO:0032184)
1.0 6.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.0 2.9 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.8 2.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.7 3.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.6 2.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.5 3.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.5 2.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.5 6.8 GO:1903136 cuprous ion binding(GO:1903136)
0.4 5.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 3.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 10.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 1.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 3.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 1.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 1.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 0.8 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 2.0 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 3.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 5.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 1.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.6 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 0.7 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 2.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 1.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.2 GO:0000832 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.6 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 2.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 4.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 3.1 GO:0019894 kinesin binding(GO:0019894)
0.1 3.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 7.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 2.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 3.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 4.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 2.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 6.9 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 2.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 2.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 12.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 3.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 1.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.6 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 ST GA12 PATHWAY G alpha 12 Pathway
0.2 2.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 8.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 6.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.6 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 3.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.8 PID EPO PATHWAY EPO signaling pathway
0.1 1.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 4.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.8 PID ATM PATHWAY ATM pathway
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 3.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 18.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 3.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 8.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 5.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 2.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 5.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis