averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
GMEB2 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000101216.6	glucocorticoid modulatory element binding protein 2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GMEB2	hg19_v2_chr20_-_62258394_62258464	0.26	1.1e-04	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_+_78833071 Show fit	84.57	ENST00000559365.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr3_-_195808980 Show fit	77.86	ENST00000360110.4	TFRC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transferrin receptor
chrX_-_149106653 Show fit	75.35	ENST00000462691.1 ENST00000370404.1 ENST00000483447.1 ENST00000370409.3	CXorf40B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome X open reading frame 40B
chr15_+_78832747 Show fit	73.45	ENST00000560217.1 ENST00000044462.7 ENST00000559082.1 ENST00000559948.1 ENST00000413382.2 ENST00000559146.1 ENST00000558281.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr8_-_80942139 Show fit	67.33	ENST00000521434.1 ENST00000519120.1 ENST00000520946.1	MRPS28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S28
chr5_-_68665084 Show fit	65.86	ENST00000509462.1	TAF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr15_+_78833105 Show fit	62.68	ENST00000558341.1 ENST00000559437.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr7_+_26240776 Show fit	61.93	ENST00000337620.4	CBX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 3
chr5_-_68665296 Show fit	60.13	ENST00000512152.1 ENST00000503245.1 ENST00000512561.1 ENST00000380822.4	TAF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr8_-_80942061 Show fit	59.71	ENST00000519386.1	MRPS28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S28
chr8_-_80942467 Show fit	59.02	ENST00000518271.1 ENST00000276585.4 ENST00000521605.1	MRPS28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S28
chr11_-_65667884 Show fit	55.55	ENST00000448083.2 ENST00000531493.1 ENST00000532401.1	FOSL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FOS-like antigen 1
chr11_-_65667997 Show fit	55.46	ENST00000312562.2 ENST00000534222.1	FOSL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FOS-like antigen 1
chr7_+_66386204 Show fit	54.21	ENST00000341567.4 ENST00000607045.1	TMEM248 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 248
chr13_+_48611665 Show fit	52.61	ENST00000258662.2	NUDT15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr5_-_68665469 Show fit	52.05	ENST00000217893.5	TAF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr14_-_21737551 Show fit	50.78	ENST00000554891.1 ENST00000555883.1 ENST00000553753.1 ENST00000555914.1 ENST00000557336.1 ENST00000555215.1 ENST00000556628.1 ENST00000555137.1 ENST00000556226.1 ENST00000555309.1 ENST00000556142.1 ENST00000554969.1 ENST00000554455.1 ENST00000556513.1 ENST00000557201.1 ENST00000420743.2 ENST00000557768.1 ENST00000553300.1 ENST00000554383.1 ENST00000554539.1	HNRNPC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr17_-_61850894 Show fit	50.32	ENST00000403162.3 ENST00000582252.1 ENST00000225726.5	CCDC47 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 47
chr15_+_66797455 Show fit	49.74	ENST00000446801.2	ZWILCH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zwilch kinetochore protein
chr1_+_42921761 Show fit	49.28	ENST00000372562.1	PPCS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphopantothenoylcysteine synthetase
chr15_+_40453204 Show fit	48.88	ENST00000287598.6 ENST00000412359.3	BUB1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BUB1 mitotic checkpoint serine/threonine kinase B
chr5_+_162887556 Show fit	48.58	ENST00000393915.4 ENST00000432118.2 ENST00000358715.3	HMMR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hyaluronan-mediated motility receptor (RHAMM)
chr2_+_187350883 Show fit	47.70	ENST00000337859.6	ZC3H15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type containing 15
chr12_-_50419177 Show fit	46.72	ENST00000454520.2 ENST00000546595.1 ENST00000548824.1 ENST00000549777.1 ENST00000546723.1 ENST00000427314.2 ENST00000552157.1 ENST00000552310.1 ENST00000548644.1 ENST00000312377.5 ENST00000546786.1 ENST00000550149.1 ENST00000546764.1 ENST00000552004.1 ENST00000548320.1 ENST00000547905.1 ENST00000550651.1 ENST00000551145.1 ENST00000434422.1 ENST00000552921.1	RACGAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rac GTPase activating protein 1
chrX_+_48433326 Show fit	46.40	ENST00000376755.1	RBM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif (RNP1, RRM) protein 3
chr2_+_216176761 Show fit	46.36	ENST00000540518.1 ENST00000435675.1	ATIC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr11_+_4116005 Show fit	46.08	ENST00000300738.5	RRM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonucleotide reductase M1
chr11_-_14665163 Show fit	45.54	ENST00000418988.2	PSMA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 1
chr2_+_187350973 Show fit	45.37	ENST00000544130.1	ZC3H15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type containing 15
chr16_-_46655538 Show fit	44.93	ENST00000303383.3	SHCBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SHC SH2-domain binding protein 1
chr15_+_66797627 Show fit	44.28	ENST00000565627.1 ENST00000564179.1	ZWILCH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zwilch kinetochore protein
chr1_-_229644034 Show fit	44.23	ENST00000366678.3 ENST00000261396.3 ENST00000537506.1	NUP133 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 133kDa
chr14_-_21737610 Show fit	42.94	ENST00000320084.7 ENST00000449098.1 ENST00000336053.6	HNRNPC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein C (C1/C2)
chrX_+_133594168 Show fit	42.41	ENST00000298556.7	HPRT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hypoxanthine phosphoribosyltransferase 1
chrX_+_48755202 Show fit	42.21	ENST00000447146.2 ENST00000376548.5 ENST00000247140.4	PQBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polyglutamine binding protein 1
chr2_-_55496174 Show fit	42.05	ENST00000417363.1 ENST00000412530.1 ENST00000394600.3 ENST00000366137.2 ENST00000420637.1	MTIF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial translational initiation factor 2
chr20_+_31407692 Show fit	41.98	ENST00000375571.5	MAPRE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein, RP/EB family, member 1
chr16_-_20911641 Show fit	41.90	ENST00000564349.1 ENST00000324344.4	ERI2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit DCUN1D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ERI1 exoribonuclease family member 2 DCN1, defective in cullin neddylation 1, domain containing 3
chr11_-_14541872 Show fit	41.78	ENST00000419365.2 ENST00000530457.1 ENST00000532256.1 ENST00000533068.1	PSMA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 1
chr5_-_176943917 Show fit	41.62	ENST00000330503.7	DDX41 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chrX_+_148622138 Show fit	41.24	ENST00000450602.2 ENST00000441248.1	CXorf40A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome X open reading frame 40A
chr1_-_220220000 Show fit	40.29	ENST00000366923.3	EPRS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamyl-prolyl-tRNA synthetase
chr3_-_49066811 Show fit	40.04	ENST00000442157.1 ENST00000326739.4	IMPDH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr1_-_161087802 Show fit	39.33	ENST00000368010.3	PFDN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prefoldin subunit 2
chr20_-_5107180 Show fit	39.19	ENST00000379160.3	PCNA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proliferating cell nuclear antigen
chr18_+_2571510 Show fit	39.11	ENST00000261597.4 ENST00000575515.1	NDC80 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDC80 kinetochore complex component
chr17_+_66511540 Show fit	38.97	ENST00000588188.2	PRKAR1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase, cAMP-dependent, regulatory, type I, alpha
chr20_-_49575058 Show fit	38.73	ENST00000371584.4 ENST00000371583.5 ENST00000413082.1	DPM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr2_-_198299726 Show fit	38.68	ENST00000409915.4 ENST00000487698.1 ENST00000414963.2 ENST00000335508.6	SF3B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	splicing factor 3b, subunit 1, 155kDa
chr12_+_7079944 Show fit	38.50	ENST00000261406.6	EMG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EMG1 N1-specific pseudouridine methyltransferase
chr8_-_117778494 Show fit	38.08	ENST00000276682.4	EIF3H Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit H
chr1_-_8939265 Show fit	37.87	ENST00000489867.1	ENO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 1, (alpha)
chr7_-_26240357 Show fit	37.71	ENST00000354667.4 ENST00000356674.7	HNRNPA2B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein A2/B1
chr15_+_52311398 Show fit	37.65	ENST00000261845.5	MAPK6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase 6
chr19_-_1095330 Show fit	37.62	ENST00000586746.1	POLR2E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr2_-_86422095 Show fit	37.59	ENST00000254636.5	IMMT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inner membrane protein, mitochondrial
chr5_+_44809027 Show fit	37.47	ENST00000507110.1	MRPS30 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S30
chr4_-_69215467 Show fit	37.44	ENST00000579690.1	YTHDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	YTH domain containing 1
chrX_+_13707235 Show fit	37.42	ENST00000464506.1	RAB9A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB9A, member RAS oncogene family
chr2_-_153573887 Show fit	37.33	ENST00000493468.2 ENST00000545856.1	PRPF40A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr1_-_87379785 Show fit	37.32	ENST00000401030.3 ENST00000370554.1	SEP15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr20_-_57617831 Show fit	36.24	ENST00000371033.5 ENST00000355937.4	SLMO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	slowmo homolog 2 (Drosophila)
chr13_+_28195988 Show fit	36.01	ENST00000399697.3 ENST00000399696.1	POLR1D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) I polypeptide D, 16kDa
chr22_+_42017280 Show fit	35.84	ENST00000402580.3 ENST00000428575.2 ENST00000359308.4	XRCC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 6
chr11_+_74660278 Show fit	35.83	ENST00000263672.6 ENST00000530257.1 ENST00000526361.1 ENST00000532972.1	SPCS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr8_+_55047763 Show fit	35.77	ENST00000260102.4 ENST00000519831.1	MRPL15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L15
chr2_+_118572226 Show fit	35.69	ENST00000263239.2	DDX18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr15_-_23034322 Show fit	35.59	ENST00000539711.2 ENST00000560039.1 ENST00000398013.3 ENST00000337451.3 ENST00000359727.4 ENST00000398014.2	NIPA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	non imprinted in Prader-Willi/Angelman syndrome 2
chr6_-_109703600 Show fit	35.50	ENST00000512821.1	CD164 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD164 molecule, sialomucin
chr5_-_68665815 Show fit	35.34	ENST00000380818.3 ENST00000328663.4	TAF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chrX_+_21958674 Show fit	35.17	ENST00000404933.2	SMS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermine synthase
chrX_-_118986911 Show fit	35.14	ENST00000276201.2 ENST00000345865.2	UPF3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UPF3 regulator of nonsense transcripts homolog B (yeast)
chr22_-_36924944 Show fit	34.74	ENST00000405442.1 ENST00000402116.1	EIF3D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit D
chr2_-_38978492 Show fit	34.46	ENST00000409276.1 ENST00000446327.2 ENST00000313117.6	SRSF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 7
chr2_-_55496344 Show fit	34.44	ENST00000403721.1 ENST00000263629.4	MTIF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial translational initiation factor 2
chr14_+_52456327 Show fit	34.41	ENST00000556760.1	C14orf166 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 166
chr2_-_153574480 Show fit	34.02	ENST00000410080.1	PRPF40A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chrX_+_23682379 Show fit	33.94	ENST00000379349.1	PRDX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxiredoxin 4
chr17_+_56769924 Show fit	33.94	ENST00000461271.1 ENST00000583539.1 ENST00000337432.4 ENST00000421782.2	RAD51C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD51 paralog C
chr1_-_246670519 Show fit	33.01	ENST00000388985.4 ENST00000490107.1	SMYD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SET and MYND domain containing 3
chr11_+_60609537 Show fit	32.99	ENST00000227520.5	CCDC86 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 86
chr15_+_59397298 Show fit	32.76	ENST00000559622.1	CCNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin B2
chrX_-_109561294 Show fit	32.54	ENST00000372059.2 ENST00000262844.5	AMMECR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr5_-_133340326 Show fit	32.46	ENST00000425992.1 ENST00000395044.3 ENST00000395047.2	VDAC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	voltage-dependent anion channel 1
chr4_-_69215699 Show fit	31.58	ENST00000510746.1 ENST00000344157.4 ENST00000355665.3	YTHDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	YTH domain containing 1
chr7_+_120590803 Show fit	31.38	ENST00000315870.5 ENST00000339121.5 ENST00000445699.1	ING3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibitor of growth family, member 3
chr21_-_46238034 Show fit	31.20	ENST00000332859.6	SUMO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 3
chrX_-_135962876 Show fit	31.18	ENST00000431446.3 ENST00000570135.1 ENST00000320676.7 ENST00000562646.1	RBMX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein, X-linked
chr9_+_110045537 Show fit	30.92	ENST00000358015.3	RAD23B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD23 homolog B (S. cerevisiae)
chr10_-_97416400 Show fit	30.91	ENST00000371224.2 ENST00000371221.3	ALDH18A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aldehyde dehydrogenase 18 family, member A1
chr1_-_19536744 Show fit	30.84	ENST00000375267.2 ENST00000375217.2 ENST00000375226.2 ENST00000375254.3	UBR4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin protein ligase E3 component n-recognin 4
chr1_-_89357179 Show fit	30.70	ENST00000448623.1 ENST00000418217.1 ENST00000370500.5	GTF2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIB
chr9_-_95056010 Show fit	30.70	ENST00000443024.2	IARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	isoleucyl-tRNA synthetase
chr22_-_36925186 Show fit	30.46	ENST00000541106.1 ENST00000455547.1 ENST00000432675.1	EIF3D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit D
chr19_-_40336969 Show fit	29.96	ENST00000599134.1 ENST00000597634.1 ENST00000598417.1 ENST00000601274.1 ENST00000594309.1 ENST00000221801.3	FBL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrillarin
chrX_+_148622513 Show fit	29.95	ENST00000393985.3 ENST00000423421.1 ENST00000423540.2 ENST00000434353.2 ENST00000514208.1	CXorf40A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome X open reading frame 40A
chr10_+_60145155 Show fit	29.95	ENST00000373895.3	TFAM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor A, mitochondrial
chr22_-_42343117 Show fit	29.93	ENST00000407253.3 ENST00000215980.5	CENPM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein M
chr22_+_42017459 Show fit	29.89	ENST00000405878.1	XRCC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 6
chrX_+_48755183 Show fit	29.70	ENST00000376563.1 ENST00000376566.4	PQBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polyglutamine binding protein 1
chr12_-_120884175 Show fit	29.48	ENST00000546954.1	TRIAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TP53 regulated inhibitor of apoptosis 1
chr12_-_102513843 Show fit	29.40	ENST00000551744.2 ENST00000552283.1	NUP37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 37kDa
chr9_+_116037922 Show fit	29.38	ENST00000374198.4	PRPF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pre-mRNA processing factor 4
chrX_+_153991025 Show fit	29.18	ENST00000369550.5	DKC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dyskeratosis congenita 1, dyskerin
chr22_+_24951436 Show fit	28.93	ENST00000215829.3	SNRPD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr19_-_18433875 Show fit	28.86	ENST00000252816.6	LSM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_+_31044413 Show fit	28.82	ENST00000394998.1	STX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	syntaxin 4
chr22_-_42342692 Show fit	28.77	ENST00000404067.1 ENST00000402338.1	CENPM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein M
chr6_-_79944336 Show fit	28.56	ENST00000344726.5 ENST00000275036.7	HMGN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group nucleosomal binding domain 3
chr4_+_17616253 Show fit	28.51	ENST00000237380.7	MED28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 28
chr11_-_102323740 Show fit	28.03	ENST00000398136.2	TMEM123 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 123
chr17_-_40169429 Show fit	28.02	ENST00000316603.7 ENST00000588641.1	DNAJC7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily C, member 7
chr3_+_184081213 Show fit	27.82	ENST00000429568.1	POLR2H Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide H
chr3_+_184081175 Show fit	27.79	ENST00000452961.1 ENST00000296223.3	POLR2H Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide H
chr21_-_30445886 Show fit	27.60	ENST00000431234.1 ENST00000540844.1 ENST00000286788.4	CCT8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 8 (theta)
chr7_+_116139744 Show fit	27.46	ENST00000343213.2	CAV2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	caveolin 2
chr1_-_200589859 Show fit	27.42	ENST00000367350.4	KIF14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kinesin family member 14
chr1_-_193075180 Show fit	27.36	ENST00000367440.3	GLRX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaredoxin 2
chr11_+_4116054 Show fit	27.15	ENST00000423050.2	RRM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonucleotide reductase M1
chr14_-_23058063 Show fit	26.93	ENST00000538631.1 ENST00000543337.1 ENST00000250498.4	DAD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	defender against cell death 1
chr21_-_46237883 Show fit	26.87	ENST00000397893.3	SUMO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 3
chr12_+_104359576 Show fit	26.84	ENST00000392872.3 ENST00000436021.2	TDG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymine-DNA glycosylase
chr3_+_184080790 Show fit	26.82	ENST00000430783.1	POLR2H Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_49337881 Show fit	26.77	ENST00000225298.7	UTP18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP18 small subunit (SSU) processome component homolog (yeast)
chr3_-_146262488 Show fit	26.68	ENST00000487389.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr6_-_75994536 Show fit	26.65	ENST00000475111.2 ENST00000230461.6	TMEM30A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 30A
chr3_-_146262365 Show fit	26.55	ENST00000448787.2	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr1_+_153606532 Show fit	26.54	ENST00000403433.1	CHTOP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromatin target of PRMT1
chr17_-_47785504 Show fit	26.43	ENST00000514907.1 ENST00000503334.1 ENST00000508520.1	SLC35B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 35, member B1
chr10_+_70883908 Show fit	26.32	ENST00000263559.6 ENST00000395098.1 ENST00000546041.1 ENST00000541711.1	VPS26A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 26 homolog A (S. pombe)
chr4_+_113558612 Show fit	26.09	ENST00000505034.1 ENST00000324052.6	LARP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	La ribonucleoprotein domain family, member 7
chr22_-_39096661 Show fit	26.08	ENST00000216039.5	JOSD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Josephin domain containing 1
chr17_+_61905058 Show fit	26.00	ENST00000375812.4 ENST00000581882.1	PSMC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase, 5
chr7_-_97501706 Show fit	25.99	ENST00000455086.1 ENST00000453600.1	ASNS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	asparagine synthetase (glutamine-hydrolyzing)
chr2_-_70520539 Show fit	25.97	ENST00000482975.2 ENST00000438261.1	SNRPG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide G
chr11_+_112097069 Show fit	25.77	ENST00000280362.3 ENST00000525803.1	PTS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	6-pyruvoyltetrahydropterin synthase
chr12_+_27863706 Show fit	25.74	ENST00000081029.3 ENST00000538315.1 ENST00000542791.1	MRPS35 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S35
chr12_+_120933904 Show fit	25.73	ENST00000550178.1 ENST00000550845.1 ENST00000549989.1 ENST00000552870.1	DYNLL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, light chain, LC8-type 1
chr1_-_155904187 Show fit	25.61	ENST00000368321.3 ENST00000368320.3	KIAA0907 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0907
chr1_-_155881156 Show fit	25.53	ENST00000539040.1 ENST00000368323.3	RIT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras-like without CAAX 1
chr15_+_59397275 Show fit	25.46	ENST00000288207.2	CCNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin B2
chr3_-_185542817 Show fit	25.42	ENST00000382199.2	IGF2BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr22_+_42017123 Show fit	25.31	ENST00000360079.3	XRCC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 6
chr20_+_56964253 Show fit	25.28	ENST00000395802.3	VAPB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr17_-_40169161 Show fit	25.20	ENST00000589586.2 ENST00000426588.3 ENST00000589576.1	DNAJC7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily C, member 7
chr2_-_132249955 Show fit	25.03	ENST00000309451.6	MZT2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitotic spindle organizing protein 2A
chr3_-_69129501 Show fit	24.99	ENST00000540295.1 ENST00000415609.2 ENST00000361055.4 ENST00000349511.4	UBA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-like modifier activating enzyme 3
chr1_+_46016703 Show fit	24.96	ENST00000481885.1 ENST00000351829.4 ENST00000471651.1	AKR1A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr11_+_47600562 Show fit	24.91	ENST00000263774.4 ENST00000529276.1 ENST00000528192.1 ENST00000530295.1 ENST00000534208.1 ENST00000534716.2	NDUFS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
chr3_+_184081137 Show fit	24.88	ENST00000443489.1	POLR2H Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide H
chr10_+_60144782 Show fit	24.81	ENST00000487519.1	TFAM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor A, mitochondrial
chr1_+_42922173 Show fit	24.38	ENST00000455780.1 ENST00000372560.3 ENST00000372561.3 ENST00000372556.3	PPCS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphopantothenoylcysteine synthetase
chr17_+_15902694 Show fit	24.30	ENST00000261647.5 ENST00000486880.2	TTC19 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tetratricopeptide repeat domain 19
chr1_-_115124257 Show fit	24.20	ENST00000369541.3	BCAS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	breast carcinoma amplified sequence 2
chr15_+_49170083 Show fit	24.09	ENST00000530028.2	EID1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EP300 interacting inhibitor of differentiation 1
chr1_+_65613340 Show fit	24.07	ENST00000546702.1	AK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylate kinase 4
chr19_-_18433910 Show fit	24.03	ENST00000594828.3 ENST00000593829.1	LSM4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_201754135 Show fit	23.93	ENST00000409357.1 ENST00000409129.2	NIF3L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr1_-_156308018 Show fit	23.91	ENST00000496684.2 ENST00000368259.2 ENST00000368261.3 ENST00000472765.2 ENST00000533194.1 ENST00000478640.2	CCT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 3 (gamma)
chr3_-_146262428 Show fit	23.73	ENST00000486631.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr1_-_87380002 Show fit	23.53	ENST00000331835.5	SEP15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr4_+_113558272 Show fit	23.45	ENST00000509061.1 ENST00000508577.1 ENST00000513553.1	LARP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	La ribonucleoprotein domain family, member 7
chr20_-_49575081 Show fit	23.37	ENST00000371588.5 ENST00000371582.4	DPM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr19_+_17416457 Show fit	23.34	ENST00000252602.1	MRPL34 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L34
chr14_-_54908043 Show fit	23.23	ENST00000556113.1 ENST00000553660.1 ENST00000395573.4 ENST00000557690.1 ENST00000216416.4	CNIH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cornichon family AMPA receptor auxiliary protein 1
chr19_+_5681153 Show fit	23.22	ENST00000579559.1 ENST00000577222.1	HSD11B1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit RPL36 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (11-beta) dehydrogenase 1-like ribosomal protein L36
chr10_-_5931794 Show fit	23.15	ENST00000380092.4 ENST00000380094.5 ENST00000191063.8	ANKRD16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 16
chr17_-_47022140 Show fit	23.06	ENST00000290330.3	SNF8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SNF8, ESCRT-II complex subunit
chr14_-_20020272 Show fit	22.92	ENST00000551509.1	POTEM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	POTE ankyrin domain family, member M
chr14_+_93260569 Show fit	22.85	ENST00000163416.2	GOLGA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	golgin A5
chr8_-_124408652 Show fit	22.74	ENST00000287394.5	ATAD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase family, AAA domain containing 2
chr2_-_70520832 Show fit	22.73	ENST00000454893.1 ENST00000272348.2	SNRPG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein polypeptide G
chr1_+_45241109 Show fit	22.67	ENST00000396651.3	RPS8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S8
chr21_-_46237959 Show fit	22.58	ENST00000397898.3 ENST00000411651.2	SUMO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 3
chr12_-_92539614 Show fit	22.48	ENST00000256015.3	BTG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B-cell translocation gene 1, anti-proliferative
chr5_+_138940742 Show fit	22.38	ENST00000398733.3 ENST00000253815.2 ENST00000505007.1	UBE2D2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 2
chr10_+_22610124 Show fit	22.32	ENST00000376663.3	BMI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BMI1 polycomb ring finger oncogene
chr12_+_120933859 Show fit	22.16	ENST00000242577.6 ENST00000548214.1 ENST00000392508.2	DYNLL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, light chain, LC8-type 1
chr1_-_235292250 Show fit	22.10	ENST00000366607.4	TOMM20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of outer mitochondrial membrane 20 homolog (yeast)
chr15_-_65281775 Show fit	22.02	ENST00000433215.2 ENST00000558415.1 ENST00000557795.1	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr9_-_127177703 Show fit	21.99	ENST00000259457.3 ENST00000536392.1 ENST00000441097.1	PSMB7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 7
chr22_+_20105259 Show fit	21.73	ENST00000416427.1 ENST00000421656.1 ENST00000423859.1 ENST00000418705.2	RANBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN binding protein 1
chr19_+_36235964 Show fit	21.65	ENST00000587708.2	PSENEN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	presenilin enhancer gamma secretase subunit
chr17_-_40169659 Show fit	21.63	ENST00000457167.4	DNAJC7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily C, member 7
chr5_-_86708670 Show fit	21.47	ENST00000504878.1	CCNH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin H
chr9_+_106856831 Show fit	21.45	ENST00000303219.8 ENST00000374787.3	SMC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 2
chrX_+_70503037 Show fit	21.41	ENST00000535149.1	NONO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	non-POU domain containing, octamer-binding
chr22_-_24316648 Show fit	21.40	ENST00000403754.3 ENST00000430101.2 ENST00000398344.4	DDT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	D-dopachrome tautomerase
chr11_-_77850629 Show fit	21.32	ENST00000376156.3 ENST00000525870.1 ENST00000530454.1 ENST00000525755.1 ENST00000527099.1 ENST00000525761.1 ENST00000299626.5	ALG8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ALG8, alpha-1,3-glucosyltransferase
chr1_+_93297582 Show fit	21.30	ENST00000370321.3	RPL5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L5
chr19_-_2427863 Show fit	21.21	ENST00000215570.3	TIMM13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr8_+_22224811 Show fit	21.19	ENST00000381237.1	SLC39A14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 39 (zinc transporter), member 14
chr2_-_86790593 Show fit	21.14	ENST00000263856.4 ENST00000409225.2	CHMP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	charged multivesicular body protein 3
chr3_-_196669298 Show fit	21.14	ENST00000411704.1 ENST00000452404.2	NCBP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear cap binding protein subunit 2, 20kDa
chr3_-_185655795 Show fit	21.12	ENST00000342294.4 ENST00000382191.4 ENST00000453386.2	TRA2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transformer 2 beta homolog (Drosophila)
chr2_-_174830430 Show fit	21.03	ENST00000310015.6 ENST00000455789.2	SP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Sp3 transcription factor
chrX_-_48755030 Show fit	20.91	ENST00000490755.2 ENST00000465150.2 ENST00000495490.2	TIMM17B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 17 homolog B (yeast)
chr2_-_86422523 Show fit	20.89	ENST00000442664.2 ENST00000409051.2 ENST00000449247.2	IMMT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inner membrane protein, mitochondrial
chr2_+_178077477 Show fit	20.87	ENST00000411529.2 ENST00000435711.1	HNRNPA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein A3
chr7_+_102988082 Show fit	20.78	ENST00000292644.3 ENST00000544811.1	PSMC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) 26S subunit, ATPase, 2

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
24.2	72.7	GO:0046098	guanine metabolic process(GO:0046098)
21.7	65.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
17.4	104.3	GO:0007296	vitellogenesis(GO:0007296)
17.3	69.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
16.4	213.4	GO:0000492	box C/D snoRNP assembly(GO:0000492)
15.6	46.7	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
15.2	91.0	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
14.5	116.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
14.0	42.0	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
13.2	52.6	GO:0006203	dGTP catabolic process(GO:0006203)
12.8	51.2	GO:0046833	snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
12.4	62.1	GO:0019348	dolichol metabolic process(GO:0019348)
12.2	73.1	GO:0031126	snoRNA 3'-end processing(GO:0031126)
11.7	35.2	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
11.7	35.2	GO:0006597	spermine biosynthetic process(GO:0006597)
11.7	46.7	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
11.6	46.4	GO:0046452	dihydrofolate metabolic process(GO:0046452)
11.1	55.3	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
11.1	44.2	GO:0051664	nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
10.3	41.3	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
10.3	30.8	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
10.2	30.7	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
10.2	40.8	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
10.0	40.1	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
9.8	39.2	GO:1902990	leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
9.6	38.5	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
9.6	76.5	GO:0032790	ribosome disassembly(GO:0032790)
8.8	35.3	GO:0035927	RNA import into mitochondrion(GO:0035927)
8.8	26.4	GO:0072334	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
8.3	25.0	GO:0007113	endomitotic cell cycle(GO:0007113)
8.3	25.0	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
7.6	22.9	GO:0009183	purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) dGDP metabolic process(GO:0046066)
7.4	22.3	GO:0061470	T follicular helper cell differentiation(GO:0061470)
7.3	29.4	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
6.8	33.9	GO:2000255	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
6.7	40.0	GO:0006177	GMP biosynthetic process(GO:0006177)
6.6	19.8	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
6.5	26.0	GO:0070981	L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
6.5	19.4	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
6.2	37.3	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
6.2	43.3	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
6.1	30.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
5.7	11.5	GO:0034971	histone H3-R17 methylation(GO:0034971)
5.7	45.5	GO:0010032	meiotic chromosome condensation(GO:0010032)
5.6	16.8	GO:1901355	response to rapamycin(GO:1901355)
5.5	44.3	GO:0015693	magnesium ion transport(GO:0015693)
5.5	60.9	GO:0045116	protein neddylation(GO:0045116)
5.5	27.4	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
5.5	21.8	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
5.5	27.3	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
5.4	54.4	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
5.4	27.0	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
5.3	74.9	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
5.3	37.4	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405)
5.3	21.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
5.3	15.8	GO:1900195	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
5.2	15.6	GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
5.2	30.9	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
5.1	41.1	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
5.1	30.7	GO:1904798	positive regulation of core promoter binding(GO:1904798)
4.9	34.3	GO:1904044	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
4.9	29.3	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
4.9	43.8	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
4.8	38.5	GO:0070475	rRNA base methylation(GO:0070475)
4.8	344.3	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
4.8	14.3	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
4.7	46.9	GO:0051096	positive regulation of helicase activity(GO:0051096)
4.6	50.3	GO:0006983	ER overload response(GO:0006983)
4.6	13.7	GO:0043060	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
4.4	8.8	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
4.4	13.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
4.4	47.9	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
4.3	446.6	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
4.3	17.2	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
4.1	77.9	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
4.0	16.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
4.0	20.0	GO:0042256	mature ribosome assembly(GO:0042256)
4.0	51.5	GO:1904871	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
3.9	27.5	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) positive regulation of dopamine receptor signaling pathway(GO:0060161) endocytosis involved in viral entry into host cell(GO:0075509)
3.9	27.4	GO:0042262	DNA protection(GO:0042262)
3.9	46.5	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
3.9	73.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
3.8	11.5	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
3.7	11.2	GO:1905068	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
3.7	11.2	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
3.7	29.5	GO:2001140	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
3.7	25.8	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
3.6	3.6	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
3.6	32.0	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
3.5	73.7	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
3.5	21.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
3.5	13.9	GO:0006382	adenosine to inosine editing(GO:0006382)
3.5	17.3	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
3.5	13.8	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
3.4	17.2	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.4	85.9	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
3.4	27.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
3.3	16.6	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
3.3	145.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
3.2	39.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
3.2	19.5	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
3.2	12.8	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
3.2	15.9	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
3.1	150.3	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
3.1	15.3	GO:1902896	terminal web assembly(GO:1902896)
3.0	12.2	GO:0072683	T cell extravasation(GO:0072683)
3.0	15.1	GO:0016476	regulation of embryonic cell shape(GO:0016476)
2.9	14.7	GO:0030047	actin modification(GO:0030047)
2.9	8.7	GO:0085032	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
2.9	8.6	GO:0016074	snoRNA metabolic process(GO:0016074)
2.9	34.4	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
2.8	70.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
2.8	8.3	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
2.7	16.5	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
2.7	10.9	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
2.6	21.1	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
2.6	41.6	GO:0035458	cellular response to interferon-beta(GO:0035458)
2.6	7.8	GO:0003420	regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
2.6	18.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
2.6	61.6	GO:0043968	histone H2A acetylation(GO:0043968)
2.5	17.8	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
2.5	72.0	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
2.5	29.8	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
2.5	14.8	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.4	26.7	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
2.3	14.1	GO:0090646	mitochondrial tRNA processing(GO:0090646)
2.3	11.7	GO:0090400	stress-induced premature senescence(GO:0090400)
2.3	11.7	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
2.3	94.5	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
2.3	20.7	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
2.3	22.7	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
2.2	58.5	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
2.2	6.6	GO:0000012	single strand break repair(GO:0000012)
2.1	21.2	GO:0071578	zinc II ion transmembrane import(GO:0071578)
2.1	8.3	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
2.1	55.4	GO:0006376	mRNA splice site selection(GO:0006376)
2.0	26.5	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
2.0	28.5	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
2.0	16.2	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
2.0	8.1	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
2.0	28.1	GO:0000154	rRNA modification(GO:0000154)
2.0	28.0	GO:0045793	positive regulation of cell size(GO:0045793)
2.0	3.9	GO:0072289	metanephric nephron tubule formation(GO:0072289)
2.0	15.7	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
2.0	52.8	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.9	9.6	GO:0030035	microspike assembly(GO:0030035)
1.9	13.4	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.9	9.5	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.9	11.3	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
1.9	22.3	GO:0007379	segment specification(GO:0007379)
1.9	7.4	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
1.8	16.5	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
1.8	12.6	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
1.8	8.9	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
1.7	22.5	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
1.7	18.8	GO:0006379	mRNA cleavage(GO:0006379)
1.7	6.8	GO:0072717	cellular response to actinomycin D(GO:0072717)
1.7	6.7	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.7	6.7	GO:0002326	B cell lineage commitment(GO:0002326)
1.6	8.2	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) positive regulation of stem cell population maintenance(GO:1902459)
1.6	13.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
1.6	250.4	GO:0045047	protein targeting to ER(GO:0045047)
1.6	6.5	GO:0002051	osteoblast fate commitment(GO:0002051)
1.6	32.5	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
1.6	63.3	GO:0043029	T cell homeostasis(GO:0043029)
1.6	24.3	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
1.6	8.1	GO:0001895	retina homeostasis(GO:0001895)
1.6	11.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
1.6	6.3	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
1.6	14.2	GO:0070933	histone H4 deacetylation(GO:0070933)
1.6	10.9	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
1.5	16.8	GO:0030043	actin filament fragmentation(GO:0030043)
1.5	42.8	GO:0030214	hyaluronan catabolic process(GO:0030214)
1.5	12.2	GO:0016926	protein desumoylation(GO:0016926)
1.5	21.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
1.5	87.5	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
1.5	38.7	GO:0000245	spliceosomal complex assembly(GO:0000245)
1.5	14.7	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.4	15.4	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
1.4	5.6	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.4	11.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
1.4	20.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
1.3	14.6	GO:0031584	activation of phospholipase D activity(GO:0031584)
1.3	9.1	GO:0045329	carnitine biosynthetic process(GO:0045329)
1.3	24.5	GO:0043486	histone exchange(GO:0043486)
1.3	3.9	GO:0033341	regulation of collagen binding(GO:0033341)
1.3	16.6	GO:0048227	plasma membrane to endosome transport(GO:0048227)
1.2	6.2	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
1.2	8.7	GO:0006284	base-excision repair(GO:0006284)
1.2	12.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.2	21.6	GO:0031293	Notch receptor processing(GO:0007220) membrane protein intracellular domain proteolysis(GO:0031293)
1.2	7.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.2	66.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.1	12.6	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
1.1	236.3	GO:0000398	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
1.1	7.9	GO:0060300	regulation of cytokine activity(GO:0060300)
1.1	19.1	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.1	15.5	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
1.1	4.4	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
1.1	14.0	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
1.1	34.3	GO:0014904	myotube cell development(GO:0014904)
1.0	3.1	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
1.0	104.9	GO:0007062	sister chromatid cohesion(GO:0007062)
1.0	8.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
1.0	6.0	GO:0071763	nuclear membrane organization(GO:0071763)
1.0	13.9	GO:0001682	tRNA 5'-leader removal(GO:0001682)
1.0	4.9	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
1.0	3.8	GO:1903438	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.9	15.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.9	7.6	GO:0033211	adiponectin-activated signaling pathway(GO:0033211) negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.9	15.0	GO:0032836	glomerular basement membrane development(GO:0032836)
0.9	17.7	GO:0006337	nucleosome disassembly(GO:0006337)
0.9	10.0	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.9	5.3	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.9	55.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.9	28.0	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.9	7.8	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.9	71.5	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.8	38.4	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.8	9.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.8	13.2	GO:0018345	protein palmitoylation(GO:0018345)
0.8	15.5	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.8	17.7	GO:0032508	DNA duplex unwinding(GO:0032508)
0.8	34.2	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.8	16.1	GO:0009303	rRNA transcription(GO:0009303)
0.8	8.3	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.8	24.8	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.7	14.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.7	4.4	GO:0035803	egg coat formation(GO:0035803)
0.7	2.9	GO:1905123	regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.7	1.4	GO:0043038	amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.7	37.7	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.7	2.8	GO:2000035	regulation of stem cell division(GO:2000035)
0.7	22.8	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.7	31.9	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.7	3.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.7	28.5	GO:0001824	blastocyst development(GO:0001824)
0.7	52.1	GO:0006446	regulation of translational initiation(GO:0006446)
0.6	14.9	GO:0002181	cytoplasmic translation(GO:0002181)
0.6	3.2	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.6	19.0	GO:0051301	cell division(GO:0051301)
0.6	19.0	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.6	55.6	GO:0006338	chromatin remodeling(GO:0006338)
0.6	12.8	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.6	13.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.6	4.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.6	19.9	GO:0050873	brown fat cell differentiation(GO:0050873)
0.6	4.6	GO:0015816	glycine transport(GO:0015816)
0.6	39.0	GO:0045727	positive regulation of translation(GO:0045727)
0.6	4.0	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.6	11.8	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.5	24.1	GO:0035065	regulation of histone acetylation(GO:0035065)
0.5	8.0	GO:0032060	bleb assembly(GO:0032060)
0.5	4.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.5	6.6	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.5	1.5	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.5	22.4	GO:0035666	TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.5	8.2	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.5	28.6	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.5	5.6	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.5	3.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.5	4.6	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.5	6.8	GO:0002227	innate immune response in mucosa(GO:0002227)
0.4	4.4	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4	4.3	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.4	5.5	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.4	9.3	GO:0070723	response to cholesterol(GO:0070723)
0.4	18.8	GO:0043171	peptide catabolic process(GO:0043171)
0.4	4.1	GO:0051865	protein autoubiquitination(GO:0051865)
0.4	9.7	GO:0046850	regulation of bone remodeling(GO:0046850)
0.4	25.4	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.4	7.2	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.4	7.9	GO:0048745	smooth muscle tissue development(GO:0048745)
0.3	5.9	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3	5.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.3	0.7	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.3	6.2	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.3	6.3	GO:0007265	Ras protein signal transduction(GO:0007265)
0.3	11.0	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.3	2.7	GO:0032264	IMP salvage(GO:0032264)
0.3	1.5	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3	5.6	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.3	1.8	GO:0044351	macropinocytosis(GO:0044351)
0.3	0.9	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2	0.9	GO:0070459	prolactin secretion(GO:0070459)
0.2	7.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.2	1.0	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.2	6.5	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.2	11.2	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2	1.0	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.2	0.5	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2	4.0	GO:1900006	positive regulation of dendrite development(GO:1900006)
0.2	3.0	GO:0048511	rhythmic process(GO:0048511)
0.2	32.3	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.1	3.6	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	1.1	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	2.2	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.1	9.8	GO:0050817	blood coagulation(GO:0007596) coagulation(GO:0050817)
0.1	0.4	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.1	0.7	GO:0006540	glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1	6.4	GO:0016266	O-glycan processing(GO:0016266)
0.1	7.8	GO:0006110	regulation of glycolytic process(GO:0006110)
0.1	0.7	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1	1.4	GO:0033141	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1	2.2	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.1	0.4	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.1	7.0	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.1	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.1	0.7	GO:0051775	response to redox state(GO:0051775)
0.1	7.9	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	10.1	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1	5.8	GO:1900046	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.1	6.0	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.1	3.2	GO:0007498	mesoderm development(GO:0007498)
0.1	1.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.4	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	2.3	GO:0051495	positive regulation of cytoskeleton organization(GO:0051495)
0.0	0.4	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	1.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	1.3	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	1.7	GO:0008283	cell proliferation(GO:0008283)
0.0	0.8	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	1.7	GO:0019827	stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0	0.4	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.3	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.0	0.4	GO:0070979	protein K11-linked ubiquitination(GO:0070979)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.7	213.4	GO:0070761	pre-snoRNP complex(GO:0070761)
25.7	308.0	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
23.5	94.0	GO:1990423	RZZ complex(GO:1990423)
20.7	62.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
18.3	73.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
18.2	91.0	GO:0043564	Ku70:Ku80 complex(GO:0043564)
18.0	71.9	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
13.1	39.2	GO:0070557	PCNA-p21 complex(GO:0070557)
13.0	39.1	GO:0031262	Ndc80 complex(GO:0031262)
12.8	51.2	GO:0005846	nuclear cap binding complex(GO:0005846)
11.7	47.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
11.5	103.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
10.0	30.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
9.7	77.6	GO:0005683	U7 snRNP(GO:0005683)
9.3	46.7	GO:0097149	centralspindlin complex(GO:0097149)
8.8	238.5	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
8.8	26.3	GO:0030906	retromer, cargo-selective complex(GO:0030906)
8.5	93.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
8.4	58.5	GO:0061617	MICOS complex(GO:0061617)
8.3	149.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
7.9	23.8	GO:0031372	UBC13-MMS2 complex(GO:0031372)
7.3	29.4	GO:0071001	U4/U6 snRNP(GO:0071001)
7.2	35.9	GO:0044530	supraspliceosomal complex(GO:0044530)
7.0	42.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
6.5	129.9	GO:0071004	U2-type prespliceosome(GO:0071004)
6.4	44.5	GO:0097452	GAIT complex(GO:0097452)
6.3	19.0	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
6.3	37.9	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
6.3	37.8	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
5.8	46.7	GO:0000322	storage vacuole(GO:0000322)
5.7	33.9	GO:0033063	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
5.6	39.3	GO:0016272	prefoldin complex(GO:0016272)
5.5	16.5	GO:0097124	Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
5.4	70.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
5.4	21.5	GO:0070985	TFIIK complex(GO:0070985)
5.4	10.7	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
5.3	63.5	GO:0031595	nuclear proteasome complex(GO:0031595)
5.3	52.9	GO:0005688	U6 snRNP(GO:0005688)
5.2	26.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
5.2	15.6	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
5.0	59.5	GO:0000346	transcription export complex(GO:0000346)
4.9	19.8	GO:0001405	presequence translocase-associated import motor(GO:0001405)
4.9	34.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
4.8	66.7	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
4.7	75.1	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
4.6	32.0	GO:0005787	signal peptidase complex(GO:0005787)
4.6	13.7	GO:0005715	late recombination nodule(GO:0005715)
4.5	40.8	GO:0000796	condensin complex(GO:0000796)
4.0	32.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
4.0	51.5	GO:0002199	zona pellucida receptor complex(GO:0002199)
3.8	15.3	GO:1990357	terminal web(GO:1990357)
3.7	74.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
3.5	17.7	GO:0071010	prespliceosome(GO:0071010)
3.5	20.9	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
3.4	80.9	GO:0005697	telomerase holoenzyme complex(GO:0005697)
3.2	9.6	GO:0044393	microspike(GO:0044393)
3.2	22.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
3.1	15.4	GO:0009368	endopeptidase Clp complex(GO:0009368)
3.0	12.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
3.0	68.7	GO:0032156	septin cytoskeleton(GO:0032156)
3.0	35.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
2.9	31.8	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.9	37.2	GO:0042555	MCM complex(GO:0042555)
2.8	14.1	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
2.8	30.7	GO:0097550	transcriptional preinitiation complex(GO:0097550)
2.8	25.0	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
2.7	21.4	GO:0042382	paraspeckles(GO:0042382)
2.7	45.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
2.6	26.5	GO:0072357	glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
2.6	61.2	GO:0036452	ESCRT complex(GO:0036452)
2.5	7.6	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
2.5	15.1	GO:0071817	MMXD complex(GO:0071817)
2.5	10.0	GO:0055087	Ski complex(GO:0055087)
2.5	34.8	GO:0000974	Prp19 complex(GO:0000974)
2.3	11.7	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
2.3	13.8	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
2.3	330.5	GO:0015934	large ribosomal subunit(GO:0015934)
2.3	29.4	GO:0031080	nuclear pore outer ring(GO:0031080)
2.3	20.3	GO:0072546	ER membrane protein complex(GO:0072546)
2.2	11.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
2.2	17.8	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
2.2	13.3	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
2.2	47.9	GO:0035145	exon-exon junction complex(GO:0035145)
2.1	15.0	GO:0031298	replication fork protection complex(GO:0031298)
2.0	12.2	GO:0072557	IPAF inflammasome complex(GO:0072557)
2.0	105.1	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.0	20.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
2.0	13.9	GO:0000172	ribonuclease MRP complex(GO:0000172)
2.0	21.6	GO:0070765	gamma-secretase complex(GO:0070765)
1.9	16.7	GO:0033588	Elongator holoenzyme complex(GO:0033588)
1.8	31.3	GO:0000109	nucleotide-excision repair complex(GO:0000109)
1.8	14.7	GO:0042612	MHC class I protein complex(GO:0042612)
1.8	15.8	GO:0072687	meiotic spindle(GO:0072687)
1.7	26.9	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
1.6	8.2	GO:0071148	TEAD-1-YAP complex(GO:0071148)
1.6	22.3	GO:0035102	PRC1 complex(GO:0035102)
1.6	10.9	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
1.6	10.9	GO:0032437	cuticular plate(GO:0032437)
1.6	28.0	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.5	28.6	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.5	161.9	GO:0000776	kinetochore(GO:0000776)
1.5	4.4	GO:0005686	U2 snRNP(GO:0005686)
1.4	14.2	GO:0030015	CCR4-NOT core complex(GO:0030015)
1.4	27.0	GO:0036020	endolysosome membrane(GO:0036020)
1.4	24.0	GO:0000812	Swr1 complex(GO:0000812)
1.4	53.0	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
1.4	17.7	GO:0001741	XY body(GO:0001741)
1.3	13.9	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
1.2	8.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
1.1	43.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
1.1	87.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
1.1	27.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
1.0	75.4	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
1.0	11.9	GO:0017119	Golgi transport complex(GO:0017119)
1.0	55.7	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.9	5.3	GO:0002177	manchette(GO:0002177) dynactin complex(GO:0005869)
0.9	27.2	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.8	9.7	GO:0010008	vacuolar membrane(GO:0005774) endosome membrane(GO:0010008)
0.8	7.2	GO:0097413	Lewy body(GO:0097413)
0.8	28.5	GO:0016592	mediator complex(GO:0016592)
0.8	33.9	GO:0005840	ribosome(GO:0005840)
0.7	22.0	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.7	16.9	GO:0070822	Sin3-type complex(GO:0070822)
0.7	5.6	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.7	49.6	GO:0005681	spliceosomal complex(GO:0005681)
0.7	5.5	GO:0097443	sorting endosome(GO:0097443)
0.7	48.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.7	68.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.7	26.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.7	45.1	GO:0072686	mitotic spindle(GO:0072686)
0.7	4.0	GO:1990130	EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.6	15.5	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.6	68.4	GO:0042734	presynaptic membrane(GO:0042734)
0.6	11.2	GO:0097342	ripoptosome(GO:0097342)
0.6	37.4	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.6	25.3	GO:0005876	spindle microtubule(GO:0005876)
0.6	4.8	GO:0016363	nuclear matrix(GO:0016363)
0.6	6.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.5	5.9	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.5	19.2	GO:0005871	kinesin complex(GO:0005871)
0.5	35.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.5	14.7	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.5	1.0	GO:0002079	inner acrosomal membrane(GO:0002079)
0.5	23.9	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.5	7.0	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.5	24.1	GO:0043195	terminal bouton(GO:0043195)
0.4	22.9	GO:0005801	cis-Golgi network(GO:0005801)
0.4	41.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.4	27.8	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.4	26.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.3	19.6	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.3	0.6	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.3	33.3	GO:0016605	PML body(GO:0016605)
0.3	19.8	GO:0035580	specific granule lumen(GO:0035580)
0.2	3.2	GO:0097433	dense body(GO:0097433)
0.2	3.5	GO:0032433	filopodium tip(GO:0032433)
0.2	81.0	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2	4.3	GO:0005844	polysome(GO:0005844)
0.2	49.4	GO:0034774	secretory granule lumen(GO:0034774)
0.2	10.1	GO:0005637	nuclear inner membrane(GO:0005637)
0.2	6.6	GO:0045171	intercellular bridge(GO:0045171)
0.2	33.4	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.2	40.9	GO:0005730	nucleolus(GO:0005730)
0.1	2.9	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1	13.6	GO:0030496	midbody(GO:0030496)
0.1	5.1	GO:0031594	neuromuscular junction(GO:0031594)
0.1	7.8	GO:0030175	filopodium(GO:0030175)
0.1	2.5	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	6.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	27.2	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	7.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	1.6	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1	6.9	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	2.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	6.8	GO:0030425	dendrite(GO:0030425)
0.1	5.1	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.4	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.8	GO:0048786	presynaptic active zone(GO:0048786)
0.0	17.4	GO:0009986	cell surface(GO:0009986)
0.0	0.5	GO:0043083	synaptic cleft(GO:0043083)
0.0	7.3	GO:0005769	early endosome(GO:0005769)
0.0	52.9	GO:0070062	extracellular exosome(GO:0070062)
0.0	5.4	GO:0005635	nuclear envelope(GO:0005635)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.0	77.9	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
20.7	62.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
18.3	73.2	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
17.5	52.6	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
15.4	200.4	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
13.6	40.8	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
12.9	181.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
12.8	383.1	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
12.4	37.3	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
11.7	46.7	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
11.0	54.8	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
10.2	30.7	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
10.1	30.3	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
10.0	40.0	GO:0003938	IMP dehydrogenase activity(GO:0003938)
9.8	39.2	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
9.6	28.9	GO:0071209	U7 snRNA binding(GO:0071209)
9.1	91.0	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
9.1	27.2	GO:0033149	FFAT motif binding(GO:0033149)
9.0	99.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
8.8	26.4	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
8.6	25.8	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
8.3	149.2	GO:0001054	RNA polymerase I activity(GO:0001054)
7.7	30.9	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
7.7	46.4	GO:0019238	cyclohydrolase activity(GO:0019238)
7.3	29.3	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
7.1	21.3	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
6.9	61.9	GO:1990226	histone methyltransferase binding(GO:1990226)
6.8	54.7	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
6.7	80.7	GO:0031386	protein tag(GO:0031386)
6.5	91.6	GO:0043024	ribosomal small subunit binding(GO:0043024)
6.4	19.3	GO:0031177	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
6.4	51.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
6.3	37.9	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
6.3	37.8	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
5.9	17.7	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
5.9	35.2	GO:0061649	ubiquitinated histone binding(GO:0061649)
5.8	64.2	GO:0008097	5S rRNA binding(GO:0008097)
5.8	63.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
5.7	91.5	GO:0008649	rRNA methyltransferase activity(GO:0008649)
5.7	33.9	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
5.5	44.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
5.5	27.4	GO:0030614	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
5.5	27.3	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
5.4	32.6	GO:0004167	dopachrome isomerase activity(GO:0004167)
5.4	16.1	GO:0005137	interleukin-5 receptor binding(GO:0005137)
5.2	26.0	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
4.9	14.7	GO:0032427	GBD domain binding(GO:0032427)
4.7	65.2	GO:0000339	RNA cap binding(GO:0000339)
4.7	37.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
4.6	82.4	GO:0017070	U6 snRNA binding(GO:0017070)
4.5	13.6	GO:0035500	MH2 domain binding(GO:0035500)
4.5	22.3	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
4.4	26.5	GO:0017018	myosin phosphatase activity(GO:0017018)
4.3	13.0	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
4.2	33.9	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
4.0	15.9	GO:1990446	U1 snRNP binding(GO:1990446)
3.7	74.8	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
3.7	33.0	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
3.6	32.5	GO:0015288	porin activity(GO:0015288)
3.6	35.7	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
3.5	24.6	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
3.5	20.9	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
3.5	13.9	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
3.5	24.3	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.5	13.8	GO:0042809	vitamin D receptor binding(GO:0042809)
3.4	109.2	GO:0070064	proline-rich region binding(GO:0070064)
3.4	10.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
3.3	52.3	GO:0035613	RNA stem-loop binding(GO:0035613)
3.3	36.0	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
3.3	13.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
3.3	16.3	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
3.0	21.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
3.0	50.8	GO:0003688	DNA replication origin binding(GO:0003688)
3.0	35.6	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
2.8	11.4	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
2.8	8.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.8	25.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
2.8	16.6	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
2.7	8.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.6	41.9	GO:0097602	cullin family protein binding(GO:0097602)
2.6	10.4	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
2.6	26.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
2.6	46.8	GO:0045505	dynein intermediate chain binding(GO:0045505)
2.6	7.8	GO:0008941	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
2.6	15.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
2.5	7.4	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
2.5	14.8	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.5	90.8	GO:0044183	protein binding involved in protein folding(GO:0044183)
2.4	80.8	GO:0001671	ATPase activator activity(GO:0001671)
2.4	19.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
2.4	9.5	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.3	34.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
2.2	44.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
2.2	8.9	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532) small protein activating enzyme binding(GO:0044388)
2.2	8.9	GO:0038025	reelin receptor activity(GO:0038025)
2.2	6.7	GO:0070644	vitamin D response element binding(GO:0070644)
2.2	84.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
2.2	59.0	GO:0000993	RNA polymerase II core binding(GO:0000993)
2.2	6.5	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
2.0	20.0	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
2.0	21.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.9	54.2	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
1.9	11.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.7	28.0	GO:0004526	ribonuclease P activity(GO:0004526)
1.7	371.0	GO:0003735	structural constituent of ribosome(GO:0003735)
1.7	37.7	GO:0004707	MAP kinase activity(GO:0004707)
1.7	13.7	GO:0032137	guanine/thymine mispair binding(GO:0032137)
1.7	5.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
1.7	22.0	GO:0042609	CD4 receptor binding(GO:0042609)
1.7	48.6	GO:0005540	hyaluronic acid binding(GO:0005540)
1.7	6.6	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
1.6	4.9	GO:0015235	cobalamin transporter activity(GO:0015235)
1.6	45.4	GO:0070717	poly-purine tract binding(GO:0070717)
1.6	12.8	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
1.6	42.0	GO:0051010	microtubule plus-end binding(GO:0051010)
1.5	17.0	GO:0046790	virion binding(GO:0046790)
1.5	12.2	GO:0016929	SUMO-specific protease activity(GO:0016929)
1.5	89.1	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.5	43.6	GO:0070182	DNA polymerase binding(GO:0070182)
1.4	11.3	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
1.4	11.2	GO:0000150	recombinase activity(GO:0000150)
1.4	59.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
1.4	12.2	GO:0035877	death effector domain binding(GO:0035877)
1.3	13.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
1.3	11.5	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.2	27.0	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.2	31.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.2	16.8	GO:0003680	AT DNA binding(GO:0003680)
1.2	24.7	GO:0008327	methyl-CpG binding(GO:0008327)
1.2	11.7	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
1.1	43.3	GO:0008536	Ran GTPase binding(GO:0008536)
1.1	19.8	GO:0030955	potassium ion binding(GO:0030955)
1.1	50.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.1	4.3	GO:0009378	four-way junction helicase activity(GO:0009378)
1.0	60.2	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
1.0	4.1	GO:0019826	oxygen sensor activity(GO:0019826)
1.0	12.8	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
1.0	26.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.0	56.9	GO:0003743	translation initiation factor activity(GO:0003743)
1.0	47.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
1.0	44.9	GO:0042169	SH2 domain binding(GO:0042169)
0.9	14.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.9	5.6	GO:0045569	TRAIL binding(GO:0045569)
0.9	19.1	GO:0050811	GABA receptor binding(GO:0050811)
0.9	17.2	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.9	56.0	GO:0035064	methylated histone binding(GO:0035064)
0.9	8.1	GO:0008312	7S RNA binding(GO:0008312)
0.9	5.3	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.9	64.2	GO:0019003	GDP binding(GO:0019003)
0.9	12.2	GO:0050700	CARD domain binding(GO:0050700)
0.8	18.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.8	13.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.8	14.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.8	4.6	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.8	4.6	GO:0046979	TAP2 binding(GO:0046979)
0.8	8.3	GO:0016421	CoA carboxylase activity(GO:0016421)
0.8	8.3	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.7	27.5	GO:0005548	phospholipid transporter activity(GO:0005548)
0.7	13.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.7	5.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.7	35.9	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.7	9.8	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.7	17.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.7	3.4	GO:0004994	somatostatin receptor activity(GO:0004994)
0.7	34.9	GO:0015485	cholesterol binding(GO:0015485)
0.7	24.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.7	7.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.6	9.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6	27.7	GO:0003785	actin monomer binding(GO:0003785)
0.6	9.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.6	40.3	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.6	2.5	GO:0004312	fatty acid synthase activity(GO:0004312)
0.6	5.5	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.6	17.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.6	10.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.6	15.4	GO:0016504	peptidase activator activity(GO:0016504)
0.6	4.1	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.6	17.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.6	3.9	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.6	7.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.5	23.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.5	10.0	GO:0031491	nucleosome binding(GO:0031491)
0.5	8.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.5	8.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.5	27.8	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.5	4.4	GO:0032190	acrosin binding(GO:0032190)
0.5	29.1	GO:0003684	damaged DNA binding(GO:0003684)
0.4	5.8	GO:0016018	cyclosporin A binding(GO:0016018)
0.4	72.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.4	1.7	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4	5.8	GO:0031996	thioesterase binding(GO:0031996)
0.4	7.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.4	3.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.4	21.8	GO:0005246	calcium channel regulator activity(GO:0005246)
0.4	15.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4	27.5	GO:0032947	protein complex scaffold(GO:0032947)
0.4	12.6	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.3	5.9	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.3	2.7	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.3	9.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.3	13.5	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.3	7.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.3	1.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3	1.5	GO:0016882	cyclo-ligase activity(GO:0016882)
0.3	2.7	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3	384.3	GO:0003723	RNA binding(GO:0003723)
0.3	2.2	GO:0035174	histone serine kinase activity(GO:0035174)
0.3	6.7	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	1.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.2	1.4	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2	1.9	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.2	1.4	GO:0050693	LBD domain binding(GO:0050693)
0.2	63.2	GO:0005525	GTP binding(GO:0005525)
0.2	5.9	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2	5.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.2	7.9	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2	11.0	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2	10.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.2	8.7	GO:0033613	activating transcription factor binding(GO:0033613)
0.2	2.9	GO:0048018	receptor agonist activity(GO:0048018)
0.1	13.6	GO:0042393	histone binding(GO:0042393)
0.1	1.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.5	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.1	9.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	3.8	GO:0050699	WW domain binding(GO:0050699)
0.1	1.4	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	1.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	10.1	GO:0044325	ion channel binding(GO:0044325)
0.1	2.0	GO:0002039	p53 binding(GO:0002039)
0.1	1.3	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	0.3	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1	23.9	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1	0.4	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	1.3	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	2.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	1.0	GO:0001848	complement binding(GO:0001848)
0.0	1.6	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	4.4	GO:0005178	integrin binding(GO:0005178)
0.0	0.7	GO:0002020	protease binding(GO:0002020)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0030331	estrogen receptor binding(GO:0030331)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.1	213.4	PID MYC PATHWAY	C-MYC pathway
3.1	107.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
2.5	278.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
2.1	128.8	PID AURORA B PATHWAY	Aurora B signaling
1.8	28.5	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.6	61.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
1.6	58.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.5	16.1	PID IL5 PATHWAY	IL5-mediated signaling events
1.5	138.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
1.2	30.7	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
1.1	39.6	PID BARD1 PATHWAY	BARD1 signaling events
1.1	25.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
1.0	28.2	PID FANCONI PATHWAY	Fanconi anemia pathway
1.0	63.1	PID NOTCH PATHWAY	Notch signaling pathway
0.9	42.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.9	68.3	PID E2F PATHWAY	E2F transcription factor network
0.9	22.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.9	44.0	PID PLK1 PATHWAY	PLK1 signaling events
0.9	39.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.9	60.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.8	39.8	PID P53 REGULATION PATHWAY	p53 pathway
0.8	20.6	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.8	39.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.8	21.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.8	14.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.7	6.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.7	27.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.7	26.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.5	41.9	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.5	8.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.5	14.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.5	9.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.5	9.7	PID ATM PATHWAY	ATM pathway
0.4	15.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.4	20.8	PID LKB1 PATHWAY	LKB1 signaling events
0.4	6.5	PID ALK2 PATHWAY	ALK2 signaling events
0.3	7.9	PID REELIN PATHWAY	Reelin signaling pathway
0.3	18.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.3	16.0	PID CDC42 PATHWAY	CDC42 signaling events
0.3	5.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	17.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.3	11.8	PID MTOR 4PATHWAY	mTOR signaling pathway
0.3	11.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.3	20.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.3	5.6	PID TRAIL PATHWAY	TRAIL signaling pathway
0.2	12.2	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.2	11.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.2	4.9	PID S1P S1P1 PATHWAY	S1P1 pathway
0.2	8.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.2	10.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.2	1.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	4.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	6.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	2.9	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	3.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	4.4	PID BCR 5PATHWAY	BCR signaling pathway
0.1	4.0	PID ARF6 PATHWAY	Arf6 signaling events
0.1	2.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	1.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.5	PID FOXO PATHWAY	FoxO family signaling
0.0	1.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	PID ATF2 PATHWAY	ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.1	128.9	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
7.9	181.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
6.1	450.6	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
5.3	15.8	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
5.2	87.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
4.1	57.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
3.8	56.8	REACTOME POL SWITCHING	Genes involved in Polymerase switching
3.7	119.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
3.6	64.9	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
3.5	52.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
3.2	340.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
3.2	79.7	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
3.0	54.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
2.9	93.4	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
2.9	61.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
2.9	94.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
2.9	97.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.8	109.0	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
2.7	362.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
2.6	52.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
2.6	48.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
2.3	46.7	REACTOME KINESINS	Genes involved in Kinesins
2.3	144.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
2.3	37.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
2.1	158.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
2.1	19.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
2.0	211.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
2.0	109.5	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
2.0	56.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
2.0	23.8	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
1.9	30.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
1.9	40.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.9	47.9	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
1.9	22.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
1.9	32.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.8	45.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.7	12.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
1.6	28.5	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
1.5	13.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.5	21.6	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
1.5	41.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.5	14.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
1.5	35.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
1.4	44.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
1.2	27.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
1.2	24.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.2	14.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
1.1	20.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.1	24.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
1.0	39.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
1.0	26.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.0	15.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
1.0	13.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.9	26.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.9	30.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.9	11.7	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.9	11.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.8	27.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.8	37.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.7	71.6	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.7	6.6	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.7	59.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.7	14.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7	8.9	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.6	10.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.6	7.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.6	21.7	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.6	12.9	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.5	8.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	4.4	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.4	18.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.4	9.4	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.4	8.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4	13.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.3	5.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3	15.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.3	23.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3	53.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3	10.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.3	8.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	3.5	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.3	4.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.3	31.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	5.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	2.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.2	6.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	5.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	3.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	6.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	6.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	8.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	3.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.8	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	4.8	REACTOME TRANSLATION	Genes involved in Translation
0.1	1.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	3.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	8.9	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	10.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	3.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane