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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HBP1

Z-value: 1.09

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Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
ENSG00000105856.9 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HBP1hg19_v2_chr7_+_106809406_106809460-0.372.7e-08Click!

Activity profile of HBP1 motif

Sorted Z-values of HBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_74425689 21.55 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr19_-_42806723 18.45 ENST00000262890.3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr2_-_10978103 16.41 ENST00000404824.2
protein disulfide isomerase family A, member 6
chr12_-_53320245 16.27 ENST00000552150.1
keratin 8
chr20_-_33872548 15.41 ENST00000374443.3
eukaryotic translation initiation factor 6
chr12_-_58146128 15.32 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr1_-_24126892 14.81 ENST00000374497.3
ENST00000425913.1
UDP-galactose-4-epimerase
chrX_+_150151752 14.19 ENST00000325307.7
high mobility group box 3
chr19_+_34855925 13.11 ENST00000590375.1
ENST00000356487.5
glucose-6-phosphate isomerase
chr19_-_10697895 13.08 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr6_-_8102279 12.54 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr2_+_235887329 12.47 ENST00000409212.1
ENST00000344528.4
ENST00000444916.1
SH3-domain binding protein 4
chr19_-_42806919 12.30 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr19_+_34855874 12.24 ENST00000588991.2
glucose-6-phosphate isomerase
chr17_+_49230897 11.89 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr2_-_220264703 11.33 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
aspartyl aminopeptidase
chrX_+_150151824 11.31 ENST00000455596.1
ENST00000448905.2
high mobility group box 3
chr5_-_140070897 10.95 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
histidyl-tRNA synthetase
chr22_+_24236191 10.44 ENST00000215754.7
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr20_-_33872518 10.40 ENST00000374436.3
eukaryotic translation initiation factor 6
chr20_-_48330377 10.08 ENST00000371711.4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr15_-_66649010 9.89 ENST00000367709.4
ENST00000261881.4
TIMELESS interacting protein
chr19_+_34856141 9.74 ENST00000586425.1
glucose-6-phosphate isomerase
chr3_-_165555200 9.47 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr11_-_65667884 9.28 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOS-like antigen 1
chr20_-_1373682 9.20 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr19_-_42806444 8.85 ENST00000594989.1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr7_-_100808843 8.63 ENST00000249330.2
VGF nerve growth factor inducible
chr11_-_65667997 8.54 ENST00000312562.2
ENST00000534222.1
FOS-like antigen 1
chr16_-_82203780 8.45 ENST00000563504.1
ENST00000569021.1
ENST00000258169.4
M-phase phosphoprotein 6
chr17_+_8152590 8.40 ENST00000584044.1
ENST00000314666.6
ENST00000545834.1
ENST00000581242.1
phosphoribosylformylglycinamidine synthase
chr3_-_197026152 8.27 ENST00000419354.1
discs, large homolog 1 (Drosophila)
chr11_-_46867780 8.27 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
cytoskeleton associated protein 5
chr3_+_100428268 8.10 ENST00000240851.4
TRK-fused gene
chr20_-_33543546 8.09 ENST00000216951.2
glutathione synthetase
chr3_+_100428188 7.86 ENST00000418917.2
ENST00000490574.1
TRK-fused gene
chr3_+_100428316 7.73 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr5_-_78809950 7.58 ENST00000334082.6
homer homolog 1 (Drosophila)
chr19_-_10305752 7.15 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNA (cytosine-5-)-methyltransferase 1
chr12_-_89746173 6.94 ENST00000308385.6
dual specificity phosphatase 6
chr22_-_18256742 6.82 ENST00000317361.7
BH3 interacting domain death agonist
chr1_+_52082751 5.85 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
oxysterol binding protein-like 9
chr7_+_65540853 5.81 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
argininosuccinate lyase
chr2_+_173292280 5.71 ENST00000264107.7
integrin, alpha 6
chr2_+_207630081 5.49 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FAST kinase domains 2
chr19_-_45927622 5.39 ENST00000300853.3
ENST00000589165.1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr10_+_13203543 5.27 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
minichromosome maintenance complex component 10
chr22_+_20105259 5.25 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr2_+_65216462 5.24 ENST00000234256.3
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_+_65540780 5.21 ENST00000304874.9
argininosuccinate lyase
chr3_-_145878954 5.15 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr3_+_58291965 5.12 ENST00000445193.3
ENST00000295959.5
ENST00000466547.1
ribonuclease P/MRP 14kDa subunit
chr20_+_25176318 5.05 ENST00000354989.5
ENST00000360031.2
ENST00000376652.4
ENST00000439162.1
ENST00000433417.1
ENST00000417467.1
ENST00000433259.2
ENST00000427553.1
ENST00000435520.1
ENST00000418890.1
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr7_+_6617039 4.96 ENST00000405731.3
ENST00000396713.2
ENST00000396707.2
ENST00000335965.6
ENST00000396709.1
ENST00000483589.1
ENST00000396706.2
zinc finger, DHHC-type containing 4
chrX_-_23926004 4.96 ENST00000379226.4
ENST00000379220.3
apolipoprotein O
chr4_-_47465666 4.90 ENST00000381571.4
COMM domain containing 8
chr9_-_127624194 4.84 ENST00000373570.4
ENST00000348462.3
ribosomal protein L35
chr12_-_124118296 4.80 ENST00000424014.2
ENST00000537073.1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr21_+_45138941 4.78 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_+_65613340 4.78 ENST00000546702.1
adenylate kinase 4
chr2_+_173292390 4.70 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
integrin, alpha 6
chr9_-_128246769 4.63 ENST00000444226.1
mitogen-activated protein kinase associated protein 1
chr9_+_127624387 4.57 ENST00000353214.2
actin related protein 2/3 complex, subunit 5-like
chr1_+_23345930 4.54 ENST00000356634.3
lysine (K)-specific demethylase 1A
chr2_+_173292301 4.51 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
integrin, alpha 6
chr1_-_31769595 4.47 ENST00000263694.4
small nuclear ribonucleoprotein 40kDa (U5)
chr6_+_30297306 4.31 ENST00000420746.1
ENST00000513556.1
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr1_-_19746236 4.29 ENST00000375144.1
capping protein (actin filament) muscle Z-line, beta
chrX_+_100663243 4.24 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr2_-_113594279 4.24 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr5_+_179921344 4.18 ENST00000261951.4
CCR4-NOT transcription complex, subunit 6
chr1_+_23345943 4.17 ENST00000400181.4
ENST00000542151.1
lysine (K)-specific demethylase 1A
chr3_+_158519654 3.80 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr2_+_27886330 3.68 ENST00000326019.6
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr8_-_130951940 3.68 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
family with sequence similarity 49, member B
chr17_+_75369167 3.59 ENST00000423034.2
septin 9
chr1_-_24127256 3.58 ENST00000418277.1
UDP-galactose-4-epimerase
chrX_+_100075368 3.56 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr16_-_28223166 3.54 ENST00000304658.5
exportin 6
chr7_-_56101826 3.53 ENST00000421626.1
phosphoserine phosphatase
chr2_-_36825281 3.52 ENST00000405912.3
ENST00000379245.4
fasciculation and elongation protein zeta 2 (zygin II)
chr4_-_119757239 3.49 ENST00000280551.6
SEC24 family member D
chr22_+_25615489 3.45 ENST00000398215.2
crystallin, beta B2
chr17_-_1588101 3.44 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
pre-mRNA processing factor 8
chr1_-_17338267 3.41 ENST00000326735.8
ATPase type 13A2
chrX_+_54834004 3.39 ENST00000375068.1
melanoma antigen family D, 2
chrX_+_51636629 3.33 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
melanoma antigen family D, 1
chr4_-_119757322 3.30 ENST00000379735.5
SEC24 family member D
chr3_-_52090461 3.27 ENST00000296483.6
ENST00000495880.1
dual specificity phosphatase 7
chr17_-_17184605 3.13 ENST00000268717.5
COP9 signalosome subunit 3
chr14_+_102430855 3.08 ENST00000360184.4
dynein, cytoplasmic 1, heavy chain 1
chr12_+_21654714 2.92 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
golgi transport 1B
chr5_+_96038476 2.92 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
calpastatin
chrX_-_70474499 2.91 ENST00000353904.2
zinc finger, MYM-type 3
chr12_+_110562135 2.83 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
intraflagellar transport 81 homolog (Chlamydomonas)
chr11_+_63742050 2.82 ENST00000314133.3
ENST00000535431.1
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr3_-_197025447 2.77 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
discs, large homolog 1 (Drosophila)
chr4_-_186696425 2.70 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr19_-_45927097 2.70 ENST00000340192.7
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr16_-_30905584 2.65 ENST00000380317.4
B-cell CLL/lymphoma 7C
chr11_+_66824346 2.65 ENST00000532559.1
ras homolog family member D
chr2_-_27886460 2.64 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr17_-_42143963 2.54 ENST00000585388.1
ENST00000293406.3
LSM12 homolog (S. cerevisiae)
chr3_-_123710199 2.52 ENST00000184183.4
rhophilin associated tail protein 1
chr8_+_15397732 2.52 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
tumor suppressor candidate 3
chr12_-_93836028 2.48 ENST00000318066.2
ubiquitin-conjugating enzyme E2N
chr11_+_43702236 2.46 ENST00000531185.1
ENST00000278353.4
hydroxysteroid (17-beta) dehydrogenase 12
chr15_+_57884199 2.42 ENST00000587652.1
ENST00000380568.3
ENST00000380565.4
ENST00000380563.2
GRINL1A complex locus 1
myocardial zonula adherens protein
polymerase (RNA) II (DNA directed) polypeptide M
chr3_+_111805182 2.36 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
chromosome 3 open reading frame 52
chr15_+_57884086 2.34 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GRINL1A complex locus 1
chr12_+_100867486 2.29 ENST00000548884.1
nuclear receptor subfamily 1, group H, member 4
chr6_+_149539767 2.16 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr6_-_41909466 2.05 ENST00000414200.2
cyclin D3
chr1_+_65613217 1.97 ENST00000545314.1
adenylate kinase 4
chr1_+_12185949 1.95 ENST00000413146.2
tumor necrosis factor receptor superfamily, member 8
chr6_-_41909561 1.90 ENST00000372991.4
cyclin D3
chr11_+_18343800 1.89 ENST00000453096.2
general transcription factor IIH, polypeptide 1, 62kDa
chr12_-_93835665 1.83 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr11_-_65363259 1.72 ENST00000342202.4
potassium channel, subfamily K, member 7
chr17_-_36904437 1.70 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
polycomb group ring finger 2
chr11_-_3818688 1.69 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
nucleoporin 98kDa
chrX_+_54834159 1.62 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
melanoma antigen family D, 2
chr4_+_26322185 1.61 ENST00000361572.6
recombination signal binding protein for immunoglobulin kappa J region
chr11_+_66824276 1.61 ENST00000308831.2
ras homolog family member D
chr20_-_23967432 1.50 ENST00000286890.4
ENST00000278765.4
gamma-glutamyltransferase light chain 1
chr11_-_18343669 1.47 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
Hermansky-Pudlak syndrome 5
chr3_+_184032283 1.47 ENST00000346169.2
ENST00000414031.1
eukaryotic translation initiation factor 4 gamma, 1
chrX_+_2746850 1.46 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
glycogenin 2
chr12_+_100867694 1.45 ENST00000392986.3
ENST00000549996.1
nuclear receptor subfamily 1, group H, member 4
chr3_+_51575596 1.41 ENST00000409535.2
RAD54-like 2 (S. cerevisiae)
chr5_+_148521136 1.41 ENST00000506113.1
actin binding LIM protein family, member 3
chr22_-_20367797 1.41 ENST00000424787.2
gamma-glutamyltransferase light chain 3
chrX_+_108779004 1.39 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr1_+_150039369 1.36 ENST00000369130.3
ENST00000369128.5
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr8_+_28174496 1.34 ENST00000518479.1
prepronociceptin
chr12_-_91398796 1.29 ENST00000261172.3
ENST00000551767.1
epiphycan
chr17_-_41856305 1.28 ENST00000397937.2
ENST00000226004.3
dual specificity phosphatase 3
chr6_+_10521574 1.27 ENST00000495262.1
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_-_4647606 1.21 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
chromosome 12 open reading frame 4
chr1_-_154832316 1.20 ENST00000361147.4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr11_+_22689648 1.13 ENST00000278187.3
growth arrest-specific 2
chr11_+_122709200 1.07 ENST00000227348.4
cytotoxic and regulatory T cell molecule
chr18_+_18943554 1.07 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chr2_-_40739501 1.00 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_+_26322409 0.91 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
recombination signal binding protein for immunoglobulin kappa J region
chr5_+_148521381 0.86 ENST00000504238.1
actin binding LIM protein family, member 3
chr8_+_110098850 0.86 ENST00000518632.1
thyrotropin-releasing hormone receptor
chr5_+_159656437 0.85 ENST00000402432.3
fatty acid binding protein 6, ileal
chr12_-_71533055 0.83 ENST00000552128.1
tetraspanin 8
chr3_+_46616017 0.82 ENST00000542931.1
teratocarcinoma-derived growth factor 1
chr13_-_44735393 0.79 ENST00000400419.1
small integral membrane protein 2
chr12_-_21654479 0.78 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RecQ protein-like (DNA helicase Q1-like)
chr5_-_147211226 0.76 ENST00000296695.5
serine peptidase inhibitor, Kazal type 1
chr1_-_27693349 0.74 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
mitogen-activated protein kinase kinase kinase 6
chr10_+_104180580 0.73 ENST00000425536.1
F-box and leucine-rich repeat protein 15
chrX_+_2746818 0.71 ENST00000398806.3
glycogenin 2
chr3_-_127455200 0.70 ENST00000398101.3
monoglyceride lipase
chr16_-_20753114 0.67 ENST00000396083.2
THUMP domain containing 1
chr1_-_151319710 0.64 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
regulatory factor X, 5 (influences HLA class II expression)
chr12_+_57984965 0.61 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr17_+_45286387 0.60 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
myosin, light chain 4, alkali; atrial, embryonic
chr7_-_99277610 0.57 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr10_+_128593978 0.56 ENST00000280333.6
dedicator of cytokinesis 1
chr15_+_75182346 0.53 ENST00000569931.1
ENST00000352410.4
ENST00000566377.1
ENST00000569233.1
ENST00000567132.1
ENST00000564633.1
ENST00000568907.1
ENST00000563422.1
ENST00000564003.1
ENST00000562800.1
ENST00000563786.1
ENST00000535694.1
ENST00000323744.6
ENST00000568828.1
ENST00000562606.1
ENST00000565576.1
ENST00000567570.1
mannose phosphate isomerase
chr20_-_39928705 0.51 ENST00000436099.2
ENST00000309060.3
ENST00000373261.1
ENST00000436440.2
ENST00000540170.1
ENST00000557816.1
ENST00000560361.1
zinc fingers and homeoboxes 3
chr22_-_30956746 0.49 ENST00000437282.1
ENST00000447224.1
ENST00000427899.1
ENST00000406955.1
ENST00000452827.1
galactose-3-O-sulfotransferase 1
chr7_+_18535786 0.47 ENST00000406072.1
histone deacetylase 9
chr3_+_5163905 0.45 ENST00000256496.3
ENST00000419534.2
ADP-ribosylation factor-like 8B
chr15_+_75074385 0.39 ENST00000220003.9
c-src tyrosine kinase
chr12_-_100378006 0.39 ENST00000547776.2
ENST00000329257.7
ENST00000547010.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr18_-_19283649 0.37 ENST00000584464.1
ENST00000578270.1
abhydrolase domain containing 3
chr22_+_22988816 0.36 ENST00000480559.1
ENST00000448514.1
gamma-glutamyltransferase light chain 2
chr5_+_125758813 0.35 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr15_+_75074410 0.31 ENST00000439220.2
c-src tyrosine kinase
chr1_-_53163992 0.29 ENST00000371538.3
cytochrome c oxidase assembly factor 7
chr5_+_140762268 0.27 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr15_-_56535464 0.27 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
regulatory factor X, 7
chr11_-_89653576 0.24 ENST00000420869.1
tripartite motif containing 49D1
chr7_+_39125365 0.19 ENST00000559001.1
ENST00000464276.2
POU class 6 homeobox 2
chr20_-_39928756 0.18 ENST00000432768.2
zinc fingers and homeoboxes 3
chr2_-_20850813 0.18 ENST00000402541.1
ENST00000406618.3
ENST00000304031.3
HCLS1 binding protein 3
chr8_-_8751068 0.17 ENST00000276282.6
malignant fibrous histiocytoma amplified sequence 1
chr3_+_44626446 0.16 ENST00000441021.1
ENST00000322734.2
zinc finger protein 660
chr12_-_18243075 0.16 ENST00000536890.1
RERG/RAS-like
chr1_+_152627927 0.15 ENST00000444515.1
ENST00000536536.1
long intergenic non-protein coding RNA 302
chr14_-_94759361 0.14 ENST00000393096.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_94759595 0.11 ENST00000261994.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr3_+_184032313 0.09 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
eukaryotic translation initiation factor 4 gamma, 1
chr11_-_57158109 0.07 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr6_-_30640811 0.04 ENST00000376442.3
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr4_-_165305086 0.02 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
6.5 25.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
3.7 11.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
3.6 10.9 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
3.2 9.5 GO:0014016 neuroblast differentiation(GO:0014016)
3.1 15.3 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
3.0 17.8 GO:0007296 vitellogenesis(GO:0007296)
2.9 8.7 GO:0046098 guanine metabolic process(GO:0046098)
2.5 7.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.1 10.4 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.0 9.9 GO:0048478 replication fork protection(GO:0048478)
1.8 7.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
1.7 6.9 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.7 5.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.6 4.8 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.6 11.0 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
1.4 18.4 GO:0019388 galactose catabolic process(GO:0019388)
1.4 4.2 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.3 8.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
1.3 5.2 GO:0015808 L-alanine transport(GO:0015808)
1.2 3.7 GO:1903314 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
1.2 16.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
1.1 3.4 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
1.1 6.7 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
1.1 5.5 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.1 10.9 GO:0018202 peptidyl-histidine modification(GO:0018202)
1.1 14.9 GO:0010668 ectodermal cell differentiation(GO:0010668) nail development(GO:0035878)
0.9 4.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.8 2.5 GO:0061317 arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.8 8.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.8 12.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.8 8.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8 2.4 GO:0051685 maintenance of ER location(GO:0051685)
0.8 4.6 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.8 21.5 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.8 9.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.7 5.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.7 5.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.7 4.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.7 6.8 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.7 2.0 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.6 3.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.6 3.7 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6 3.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.4 4.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4 3.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 3.0 GO:0006751 glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4 8.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 6.5 GO:0002021 response to dietary excess(GO:0002021)
0.3 6.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 1.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 4.3 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.3 3.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 36.8 GO:0006903 vesicle targeting(GO:0006903)
0.3 5.1 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.3 2.5 GO:0015693 magnesium ion transport(GO:0015693)
0.3 8.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.3 5.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 10.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.3 0.8 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749) negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2 8.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.2 4.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.2 2.9 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 23.1 GO:0032392 DNA geometric change(GO:0032392)
0.2 3.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 3.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 16.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 1.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 2.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 3.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 1.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 5.3 GO:0006270 DNA replication initiation(GO:0006270)
0.1 5.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.6 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.7 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 2.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.9 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 5.0 GO:0042407 cristae formation(GO:0042407)
0.1 3.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 4.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0048867 stem cell fate determination(GO:0048867)
0.1 2.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 4.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 6.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 2.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 2.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 2.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 0.9 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 0.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.8 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 2.2 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.6 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 14.7 GO:0016042 lipid catabolic process(GO:0016042)
0.0 3.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 2.8 GO:0006915 apoptotic process(GO:0006915)
0.0 0.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 1.2 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 4.8 GO:0009408 response to heat(GO:0009408)
0.0 0.7 GO:0000154 rRNA modification(GO:0000154)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 7.7 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.7 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.8 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.0 1.5 GO:0043473 pigmentation(GO:0043473)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 14.9 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
2.6 15.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.8 9.2 GO:1990425 ryanodine receptor complex(GO:1990425)
1.7 15.2 GO:0031298 replication fork protection complex(GO:0031298)
1.4 4.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
1.2 8.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.9 11.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.9 16.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.9 3.4 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.8 23.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.8 25.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.8 8.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.6 9.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.6 4.3 GO:0071203 WASH complex(GO:0071203)
0.6 4.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6 12.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5 2.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5 16.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.5 6.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.5 3.3 GO:0061617 MICOS complex(GO:0061617)
0.4 5.1 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.3 33.2 GO:0060170 ciliary membrane(GO:0060170)
0.3 4.5 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.3 3.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 13.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 1.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.3 7.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.3 8.3 GO:0035371 microtubule plus-end(GO:0035371)
0.3 4.6 GO:0031932 TORC2 complex(GO:0031932)
0.2 4.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 4.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 1.7 GO:0001739 sex chromatin(GO:0001739)
0.2 3.6 GO:0031105 septin complex(GO:0031105)
0.2 2.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 2.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 11.3 GO:0072562 blood microparticle(GO:0072562)
0.2 8.7 GO:1990391 DNA repair complex(GO:1990391)
0.2 17.8 GO:0042734 presynaptic membrane(GO:0042734)
0.2 7.6 GO:0043034 costamere(GO:0043034)
0.2 17.1 GO:0005882 intermediate filament(GO:0005882)
0.2 2.6 GO:0030914 STAGA complex(GO:0030914)
0.2 12.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 3.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 3.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 6.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 10.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 5.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 3.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 5.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.5 GO:0031082 BLOC complex(GO:0031082)
0.1 4.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 3.1 GO:0008180 COP9 signalosome(GO:0008180)
0.1 4.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 6.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 8.0 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.9 GO:0030424 axon(GO:0030424)
0.0 19.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 55.0 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.1 GO:0005884 actin filament(GO:0005884)
0.0 0.6 GO:0031672 A band(GO:0031672)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
7.9 39.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
7.2 21.5 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
6.1 18.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
5.2 25.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
3.6 10.9 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
2.9 8.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
2.4 9.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
1.7 10.4 GO:0004167 dopachrome isomerase activity(GO:0004167)
1.7 5.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.7 11.9 GO:0004673 protein histidine kinase activity(GO:0004673)
1.7 6.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.4 11.0 GO:0016842 amidine-lyase activity(GO:0016842)
1.3 5.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.2 3.7 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
1.2 7.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.2 8.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.1 14.9 GO:0038132 neuregulin binding(GO:0038132)
1.1 3.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.0 5.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
1.0 11.0 GO:0097016 L27 domain binding(GO:0097016)
0.9 25.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.9 10.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.8 2.5 GO:0000150 recombinase activity(GO:0000150)
0.8 16.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7 11.5 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.7 17.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.7 3.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.7 9.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.6 3.7 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.6 8.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.6 7.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.6 8.1 GO:0016594 glycine binding(GO:0016594)
0.6 3.4 GO:1903135 cupric ion binding(GO:1903135)
0.5 2.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.5 11.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.5 2.5 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.5 2.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4 15.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 1.0 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 5.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 5.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 5.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 8.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 2.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 12.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 4.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 4.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 4.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 4.8 GO:0030955 potassium ion binding(GO:0030955)
0.2 8.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 6.8 GO:0005123 death receptor binding(GO:0005123)
0.2 3.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 16.3 GO:0097110 scaffold protein binding(GO:0097110)
0.2 0.8 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 2.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 3.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 1.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 1.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 5.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.6 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 3.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 4.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 5.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.5 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.9 GO:0032052 bile acid binding(GO:0032052)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 2.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 5.4 GO:0000149 SNARE binding(GO:0000149)
0.0 2.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 18.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.6 GO:0070330 aromatase activity(GO:0070330)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 7.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 7.9 GO:0045296 cadherin binding(GO:0045296)
0.0 1.5 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 18.0 GO:0042802 identical protein binding(GO:0042802)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 42.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.6 14.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.6 15.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 9.2 PID ALK2 PATHWAY ALK2 signaling events
0.5 11.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 17.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 6.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 14.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 10.7 PID IL1 PATHWAY IL1-mediated signaling events
0.2 11.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 11.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 6.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 9.5 PID ATR PATHWAY ATR signaling pathway
0.2 11.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 7.4 PID AURORA A PATHWAY Aurora A signaling
0.1 4.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 3.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 5.2 PID E2F PATHWAY E2F transcription factor network
0.1 2.6 PID MYC PATHWAY C-MYC pathway
0.1 2.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8 35.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 11.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.7 23.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.6 9.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5 8.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 11.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 10.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.4 4.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.4 9.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 2.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 11.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 19.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 6.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 1.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 8.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 16.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 6.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 2.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 4.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 3.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 7.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 5.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 5.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 11.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 5.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 4.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 4.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 5.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 10.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 5.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 4.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 9.5 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 3.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 7.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 5.8 REACTOME TRANSLATION Genes involved in Translation
0.0 4.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism