averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
HBP1 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000105856.9	HMG-box transcription factor 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HBP1	hg19_v2_chr7_+_106809406_106809460	-0.37	2.7e-08	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_74425689 Show fit	21.55	ENST00000394053.2 ENST00000409804.1 ENST00000264090.4 ENST00000394050.3 ENST00000409601.1	MTHFD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr19_-_42806723 Show fit	18.45	ENST00000262890.3	PAFAH1B3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr2_-_10978103 Show fit	16.41	ENST00000404824.2	PDIA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein disulfide isomerase family A, member 6
chr12_-_53320245 Show fit	16.27	ENST00000552150.1	KRT8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 8
chr20_-_33872548 Show fit	15.41	ENST00000374443.3	EIF6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 6
chr12_-_58146128 Show fit	15.32	ENST00000551800.1 ENST00000549606.1 ENST00000257904.6	CDK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 4
chr1_-_24126892 Show fit	14.81	ENST00000374497.3 ENST00000425913.1	GALE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-galactose-4-epimerase
chrX_+_150151752 Show fit	14.19	ENST00000325307.7	HMGB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group box 3
chr19_+_34855925 Show fit	13.11	ENST00000590375.1 ENST00000356487.5	GPI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glucose-6-phosphate isomerase
chr19_-_10697895 Show fit	13.08	ENST00000591240.1 ENST00000589684.1 ENST00000591676.1 ENST00000250244.6 ENST00000590923.1	AP1M2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 1, mu 2 subunit
chr6_-_8102279 Show fit	12.54	ENST00000488226.2	EEF1E1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation elongation factor 1 epsilon 1
chr2_+_235887329 Show fit	12.47	ENST00000409212.1 ENST00000344528.4 ENST00000444916.1	SH3BP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3-domain binding protein 4
chr19_-_42806919 Show fit	12.30	ENST00000595530.1 ENST00000538771.1 ENST00000601865.1	PAFAH1B3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr19_+_34855874 Show fit	12.24	ENST00000588991.2	GPI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glucose-6-phosphate isomerase
chr17_+_49230897 Show fit	11.89	ENST00000393196.3 ENST00000336097.3 ENST00000480143.1 ENST00000511355.1 ENST00000013034.3 ENST00000393198.3 ENST00000608447.1 ENST00000393193.2 ENST00000376392.6 ENST00000555572.1	NME1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit NME1-NME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit NME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NME/NM23 nucleoside diphosphate kinase 1 NME1-NME2 readthrough NME/NM23 nucleoside diphosphate kinase 2
chr2_-_220264703 Show fit	11.33	ENST00000519905.1 ENST00000523282.1 ENST00000434339.1 ENST00000457935.1	DNPEP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aspartyl aminopeptidase
chrX_+_150151824 Show fit	11.31	ENST00000455596.1 ENST00000448905.2	HMGB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group box 3
chr5_-_140070897 Show fit	10.95	ENST00000448240.1 ENST00000438307.2 ENST00000415192.2 ENST00000457527.2 ENST00000307633.3 ENST00000507746.1 ENST00000431330.2	HARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histidyl-tRNA synthetase
chr22_+_24236191 Show fit	10.44	ENST00000215754.7	MIF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr20_-_33872518 Show fit	10.40	ENST00000374436.3	EIF6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 6
chr20_-_48330377 Show fit	10.08	ENST00000371711.4	B4GALT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr15_-_66649010 Show fit	9.89	ENST00000367709.4 ENST00000261881.4	TIPIN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TIMELESS interacting protein
chr19_+_34856141 Show fit	9.74	ENST00000586425.1	GPI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glucose-6-phosphate isomerase
chr3_-_165555200 Show fit	9.47	ENST00000479451.1 ENST00000540653.1 ENST00000488954.1 ENST00000264381.3	BCHE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrylcholinesterase
chr11_-_65667884 Show fit	9.28	ENST00000448083.2 ENST00000531493.1 ENST00000532401.1	FOSL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FOS-like antigen 1
chr20_-_1373682 Show fit	9.20	ENST00000381724.3	FKBP1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FK506 binding protein 1A, 12kDa
chr19_-_42806444 Show fit	8.85	ENST00000594989.1	PAFAH1B3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr7_-_100808843 Show fit	8.63	ENST00000249330.2	VGF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	VGF nerve growth factor inducible
chr11_-_65667997 Show fit	8.54	ENST00000312562.2 ENST00000534222.1	FOSL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FOS-like antigen 1
chr16_-_82203780 Show fit	8.45	ENST00000563504.1 ENST00000569021.1 ENST00000258169.4	MPHOSPH6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	M-phase phosphoprotein 6
chr17_+_8152590 Show fit	8.40	ENST00000584044.1 ENST00000314666.6 ENST00000545834.1 ENST00000581242.1	PFAS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoribosylformylglycinamidine synthase
chr3_-_197026152 Show fit	8.27	ENST00000419354.1	DLG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	discs, large homolog 1 (Drosophila)
chr11_-_46867780 Show fit	8.27	ENST00000529230.1 ENST00000415402.1 ENST00000312055.5	CKAP5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoskeleton associated protein 5
chr3_+_100428268 Show fit	8.10	ENST00000240851.4	TFG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr20_-_33543546 Show fit	8.09	ENST00000216951.2	GSS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutathione synthetase
chr3_+_100428188 Show fit	7.86	ENST00000418917.2 ENST00000490574.1	TFG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr3_+_100428316 Show fit	7.73	ENST00000479672.1 ENST00000476228.1 ENST00000463568.1	TFG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TRK-fused gene
chr5_-_78809950 Show fit	7.58	ENST00000334082.6	HOMER1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homer homolog 1 (Drosophila)
chr19_-_10305752 Show fit	7.15	ENST00000540357.1 ENST00000359526.4 ENST00000340748.4	DNMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DNA (cytosine-5-)-methyltransferase 1
chr12_-_89746173 Show fit	6.94	ENST00000308385.6	DUSP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 6
chr22_-_18256742 Show fit	6.82	ENST00000317361.7	BID Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BH3 interacting domain death agonist
chr1_+_52082751 Show fit	5.85	ENST00000447887.1 ENST00000435686.2 ENST00000428468.1 ENST00000453295.1	OSBPL9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	oxysterol binding protein-like 9
chr7_+_65540853 Show fit	5.81	ENST00000380839.4 ENST00000395332.3 ENST00000362000.5 ENST00000395331.3	ASL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	argininosuccinate lyase
chr2_+_173292280 Show fit	5.71	ENST00000264107.7	ITGA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 6
chr2_+_207630081 Show fit	5.49	ENST00000236980.6 ENST00000418289.1 ENST00000402774.3 ENST00000403094.3	FASTKD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FAST kinase domains 2
chr19_-_45927622 Show fit	5.39	ENST00000300853.3 ENST00000589165.1	ERCC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr10_+_13203543 Show fit	5.27	ENST00000378714.3 ENST00000479669.1 ENST00000484800.2	MCM10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 10
chr22_+_20105259 Show fit	5.25	ENST00000416427.1 ENST00000421656.1 ENST00000423859.1 ENST00000418705.2	RANBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN binding protein 1
chr2_+_65216462 Show fit	5.24	ENST00000234256.3	SLC1A4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_+_65540780 Show fit	5.21	ENST00000304874.9	ASL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	argininosuccinate lyase
chr3_-_145878954 Show fit	5.15	ENST00000282903.5 ENST00000360060.3	PLOD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr3_+_58291965 Show fit	5.12	ENST00000445193.3 ENST00000295959.5 ENST00000466547.1	RPP14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonuclease P/MRP 14kDa subunit
chr20_+_25176318 Show fit	5.05	ENST00000354989.5 ENST00000360031.2 ENST00000376652.4 ENST00000439162.1 ENST00000433417.1 ENST00000417467.1 ENST00000433259.2 ENST00000427553.1 ENST00000435520.1 ENST00000418890.1	ENTPD6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr7_+_6617039 Show fit	4.96	ENST00000405731.3 ENST00000396713.2 ENST00000396707.2 ENST00000335965.6 ENST00000396709.1 ENST00000483589.1 ENST00000396706.2	ZDHHC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, DHHC-type containing 4
chrX_-_23926004 Show fit	4.96	ENST00000379226.4 ENST00000379220.3	APOO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein O
chr4_-_47465666 Show fit	4.90	ENST00000381571.4	COMMD8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 8
chr9_-_127624194 Show fit	4.84	ENST00000373570.4 ENST00000348462.3	RPL35 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein L35
chr12_-_124118296 Show fit	4.80	ENST00000424014.2 ENST00000537073.1	EIF2B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr21_+_45138941 Show fit	4.78	ENST00000398081.1 ENST00000468090.1 ENST00000291565.4	PDXK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pyridoxal (pyridoxine, vitamin B6) kinase
chr1_+_65613340 Show fit	4.78	ENST00000546702.1	AK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylate kinase 4
chr2_+_173292390 Show fit	4.70	ENST00000442250.1 ENST00000458358.1 ENST00000409080.1	ITGA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 6
chr9_-_128246769 Show fit	4.63	ENST00000444226.1	MAPKAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase associated protein 1
chr9_+_127624387 Show fit	4.57	ENST00000353214.2	ARPC5L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 5-like
chr1_+_23345930 Show fit	4.54	ENST00000356634.3	KDM1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 1A
chr2_+_173292301 Show fit	4.51	ENST00000264106.6 ENST00000375221.2 ENST00000343713.4	ITGA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 6
chr1_-_31769595 Show fit	4.47	ENST00000263694.4	SNRNP40 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein 40kDa (U5)
chr6_+_30297306 Show fit	4.31	ENST00000420746.1 ENST00000513556.1	TRIM39 Links Ensembl NCBI GeneCards UniProt NextProt Show fit TRIM39-RPP21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 39 TRIM39-RPP21 readthrough
chr1_-_19746236 Show fit	4.29	ENST00000375144.1	CAPZB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	capping protein (actin filament) muscle Z-line, beta
chrX_+_100663243 Show fit	4.24	ENST00000316594.5	HNRNPH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein H2 (H')
chr2_-_113594279 Show fit	4.24	ENST00000416750.1 ENST00000418817.1 ENST00000263341.2	IL1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 1, beta
chr5_+_179921344 Show fit	4.18	ENST00000261951.4	CNOT6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CCR4-NOT transcription complex, subunit 6
chr1_+_23345943 Show fit	4.17	ENST00000400181.4 ENST00000542151.1	KDM1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 1A
chr3_+_158519654 Show fit	3.80	ENST00000415822.2 ENST00000392813.4 ENST00000264266.8	MFSD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major facilitator superfamily domain containing 1
chr2_+_27886330 Show fit	3.68	ENST00000326019.6	SLC4A1AP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr8_-_130951940 Show fit	3.68	ENST00000522250.1 ENST00000522941.1 ENST00000522746.1 ENST00000520204.1 ENST00000519070.1 ENST00000520254.1 ENST00000519824.2 ENST00000519540.1	FAM49B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 49, member B
chr17_+_75369167 Show fit	3.59	ENST00000423034.2	SEPT9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	septin 9
chr1_-_24127256 Show fit	3.58	ENST00000418277.1	GALE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-galactose-4-epimerase
chrX_+_100075368 Show fit	3.56	ENST00000415585.2 ENST00000372972.2 ENST00000413437.1	CSTF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr16_-_28223166 Show fit	3.54	ENST00000304658.5	XPO6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	exportin 6
chr7_-_56101826 Show fit	3.53	ENST00000421626.1	PSPH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoserine phosphatase
chr2_-_36825281 Show fit	3.52	ENST00000405912.3 ENST00000379245.4	FEZ2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fasciculation and elongation protein zeta 2 (zygin II)
chr4_-_119757239 Show fit	3.49	ENST00000280551.6	SEC24D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC24 family member D
chr22_+_25615489 Show fit	3.45	ENST00000398215.2	CRYBB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, beta B2
chr17_-_1588101 Show fit	3.44	ENST00000577001.1 ENST00000572621.1 ENST00000304992.6	PRPF8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pre-mRNA processing factor 8
chr1_-_17338267 Show fit	3.41	ENST00000326735.8	ATP13A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase type 13A2
chrX_+_54834004 Show fit	3.39	ENST00000375068.1	MAGED2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family D, 2
chrX_+_51636629 Show fit	3.33	ENST00000375722.1 ENST00000326587.7 ENST00000375695.2	MAGED1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family D, 1
chr4_-_119757322 Show fit	3.30	ENST00000379735.5	SEC24D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC24 family member D
chr3_-_52090461 Show fit	3.27	ENST00000296483.6 ENST00000495880.1	DUSP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 7
chr17_-_17184605 Show fit	3.13	ENST00000268717.5	COPS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COP9 signalosome subunit 3
chr14_+_102430855 Show fit	3.08	ENST00000360184.4	DYNC1H1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, cytoplasmic 1, heavy chain 1
chr12_+_21654714 Show fit	2.92	ENST00000542038.1 ENST00000540141.1 ENST00000229314.5	GOLT1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	golgi transport 1B
chr5_+_96038476 Show fit	2.92	ENST00000511049.1 ENST00000309190.5 ENST00000510156.1 ENST00000509903.1 ENST00000511782.1 ENST00000504465.1	CAST Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calpastatin
chrX_-_70474499 Show fit	2.91	ENST00000353904.2	ZMYM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, MYM-type 3
chr12_+_110562135 Show fit	2.83	ENST00000361948.4 ENST00000552912.1 ENST00000242591.5 ENST00000546374.1	IFT81 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intraflagellar transport 81 homolog (Chlamydomonas)
chr11_+_63742050 Show fit	2.82	ENST00000314133.3 ENST00000535431.1	COX8A Links Ensembl NCBI GeneCards UniProt NextProt Show fit AP000721.4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome c oxidase subunit VIIIA (ubiquitous) Uncharacterized protein
chr3_-_197025447 Show fit	2.77	ENST00000346964.2 ENST00000357674.4 ENST00000314062.3 ENST00000448528.2 ENST00000419553.1	DLG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	discs, large homolog 1 (Drosophila)
chr4_-_186696425 Show fit	2.70	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorbin and SH3 domain containing 2
chr19_-_45927097 Show fit	2.70	ENST00000340192.7	ERCC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr16_-_30905584 Show fit	2.65	ENST00000380317.4	BCL7C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B-cell CLL/lymphoma 7C
chr11_+_66824346 Show fit	2.65	ENST00000532559.1	RHOD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member D
chr2_-_27886460 Show fit	2.64	ENST00000404798.2 ENST00000405491.1 ENST00000464789.2 ENST00000406540.1	SUPT7L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of Ty 7 (S. cerevisiae)-like
chr17_-_42143963 Show fit	2.54	ENST00000585388.1 ENST00000293406.3	LSM12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM12 homolog (S. cerevisiae)
chr3_-_123710199 Show fit	2.52	ENST00000184183.4	ROPN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	rhophilin associated tail protein 1
chr8_+_15397732 Show fit	2.52	ENST00000382020.4 ENST00000506802.1 ENST00000509380.1 ENST00000503731.1	TUSC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor suppressor candidate 3
chr12_-_93836028 Show fit	2.48	ENST00000318066.2	UBE2N Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2N
chr11_+_43702236 Show fit	2.46	ENST00000531185.1 ENST00000278353.4	HSD17B12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (17-beta) dehydrogenase 12
chr15_+_57884199 Show fit	2.42	ENST00000587652.1 ENST00000380568.3 ENST00000380565.4 ENST00000380563.2	GCOM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit MYZAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit POLR2M Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GRINL1A complex locus 1 myocardial zonula adherens protein polymerase (RNA) II (DNA directed) polypeptide M
chr3_+_111805182 Show fit	2.36	ENST00000430855.1 ENST00000431717.2 ENST00000264848.5	C3orf52 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 3 open reading frame 52
chr15_+_57884086 Show fit	2.34	ENST00000380569.2 ENST00000380561.2 ENST00000574161.1 ENST00000572390.1 ENST00000396180.1 ENST00000380560.2	GCOM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GRINL1A complex locus 1
chr12_+_100867486 Show fit	2.29	ENST00000548884.1	NR1H4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 1, group H, member 4
chr6_+_149539767 Show fit	2.16	ENST00000606202.1 ENST00000536230.1 ENST00000445901.1	TAB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit RP1-111D6.3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TGF-beta activated kinase 1/MAP3K7 binding protein 2 RP1-111D6.3
chr6_-_41909466 Show fit	2.05	ENST00000414200.2	CCND3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D3
chr1_+_65613217 Show fit	1.97	ENST00000545314.1	AK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylate kinase 4
chr1_+_12185949 Show fit	1.95	ENST00000413146.2	TNFRSF8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor receptor superfamily, member 8
chr6_-_41909561 Show fit	1.90	ENST00000372991.4	CCND3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D3
chr11_+_18343800 Show fit	1.89	ENST00000453096.2	GTF2H1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIH, polypeptide 1, 62kDa
chr12_-_93835665 Show fit	1.83	ENST00000552442.1 ENST00000550657.1	UBE2N Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2N
chr11_-_65363259 Show fit	1.72	ENST00000342202.4	KCNK7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium channel, subfamily K, member 7
chr17_-_36904437 Show fit	1.70	ENST00000585100.1 ENST00000360797.2 ENST00000578109.1 ENST00000579882.1	PCGF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polycomb group ring finger 2
chr11_-_3818688 Show fit	1.69	ENST00000355260.3 ENST00000397004.4 ENST00000397007.4 ENST00000532475.1	NUP98 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 98kDa
chrX_+_54834159 Show fit	1.62	ENST00000375053.2 ENST00000347546.4 ENST00000375062.4	MAGED2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family D, 2
chr4_+_26322185 Show fit	1.61	ENST00000361572.6	RBPJ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr11_+_66824276 Show fit	1.61	ENST00000308831.2	RHOD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member D
chr20_-_23967432 Show fit	1.50	ENST00000286890.4 ENST00000278765.4	GGTLC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gamma-glutamyltransferase light chain 1
chr11_-_18343669 Show fit	1.47	ENST00000396253.3 ENST00000349215.3 ENST00000438420.2	HPS5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Hermansky-Pudlak syndrome 5
chr3_+_184032283 Show fit	1.47	ENST00000346169.2 ENST00000414031.1	EIF4G1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 4 gamma, 1
chrX_+_2746850 Show fit	1.46	ENST00000381163.3 ENST00000338623.5 ENST00000542787.1	GYG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glycogenin 2
chr12_+_100867694 Show fit	1.45	ENST00000392986.3 ENST00000549996.1	NR1H4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 1, group H, member 4
chr3_+_51575596 Show fit	1.41	ENST00000409535.2	RAD54L2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD54-like 2 (S. cerevisiae)
chr5_+_148521136 Show fit	1.41	ENST00000506113.1	ABLIM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin binding LIM protein family, member 3
chr22_-_20367797 Show fit	1.41	ENST00000424787.2	GGTLC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gamma-glutamyltransferase light chain 3
chrX_+_108779004 Show fit	1.39	ENST00000218004.1	NXT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear transport factor 2-like export factor 2
chr1_+_150039369 Show fit	1.36	ENST00000369130.3 ENST00000369128.5	VPS45 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 45 homolog (S. cerevisiae)
chr8_+_28174496 Show fit	1.34	ENST00000518479.1	PNOC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prepronociceptin
chr12_-_91398796 Show fit	1.29	ENST00000261172.3 ENST00000551767.1	EPYC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epiphycan
chr17_-_41856305 Show fit	1.28	ENST00000397937.2 ENST00000226004.3	DUSP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 3
chr6_+_10521574 Show fit	1.27	ENST00000495262.1	GCNT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_-_4647606 Show fit	1.21	ENST00000261250.3 ENST00000541014.1 ENST00000545746.1 ENST00000542080.1	C12orf4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 12 open reading frame 4
chr1_-_154832316 Show fit	1.20	ENST00000361147.4	KCNN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr11_+_22689648 Show fit	1.13	ENST00000278187.3	GAS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth arrest-specific 2
chr11_+_122709200 Show fit	1.07	ENST00000227348.4	CRTAM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytotoxic and regulatory T cell molecule
chr18_+_18943554 Show fit	1.07	ENST00000580732.2	GREB1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth regulation by estrogen in breast cancer-like
chr2_-_40739501 Show fit	1.00	ENST00000403092.1 ENST00000402441.1 ENST00000448531.1	SLC8A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_+_26322409 Show fit	0.91	ENST00000514807.1 ENST00000348160.4 ENST00000509158.1 ENST00000355476.3	RBPJ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr5_+_148521381 Show fit	0.86	ENST00000504238.1	ABLIM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin binding LIM protein family, member 3
chr8_+_110098850 Show fit	0.86	ENST00000518632.1	TRHR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyrotropin-releasing hormone receptor
chr5_+_159656437 Show fit	0.85	ENST00000402432.3	FABP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 6, ileal
chr12_-_71533055 Show fit	0.83	ENST00000552128.1	TSPAN8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tetraspanin 8
chr3_+_46616017 Show fit	0.82	ENST00000542931.1	TDGF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	teratocarcinoma-derived growth factor 1
chr13_-_44735393 Show fit	0.79	ENST00000400419.1	SMIM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small integral membrane protein 2
chr12_-_21654479 Show fit	0.78	ENST00000421138.2 ENST00000444129.2 ENST00000539672.1 ENST00000542432.1 ENST00000536964.1 ENST00000536240.1 ENST00000396093.3 ENST00000314748.6	RECQL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RecQ protein-like (DNA helicase Q1-like)
chr5_-_147211226 Show fit	0.76	ENST00000296695.5	SPINK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine peptidase inhibitor, Kazal type 1
chr1_-_27693349 Show fit	0.74	ENST00000374040.3 ENST00000357582.2 ENST00000493901.1	MAP3K6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase kinase kinase 6
chr10_+_104180580 Show fit	0.73	ENST00000425536.1	FBXL15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	F-box and leucine-rich repeat protein 15
chrX_+_2746818 Show fit	0.71	ENST00000398806.3	GYG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glycogenin 2
chr3_-_127455200 Show fit	0.70	ENST00000398101.3	MGLL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	monoglyceride lipase
chr16_-_20753114 Show fit	0.67	ENST00000396083.2	THUMPD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	THUMP domain containing 1
chr1_-_151319710 Show fit	0.64	ENST00000290524.4 ENST00000437327.1 ENST00000452513.2 ENST00000368870.2 ENST00000452671.2	RFX5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulatory factor X, 5 (influences HLA class II expression)
chr12_+_57984965 Show fit	0.61	ENST00000540759.2 ENST00000551772.1 ENST00000550465.1 ENST00000354947.5	PIP4K2C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr17_+_45286387 Show fit	0.60	ENST00000572316.1 ENST00000354968.1 ENST00000576874.1 ENST00000536623.2	MYL4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 4, alkali; atrial, embryonic
chr7_-_99277610 Show fit	0.57	ENST00000343703.5 ENST00000222982.4 ENST00000439761.1 ENST00000339843.2	CYP3A5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome P450, family 3, subfamily A, polypeptide 5
chr10_+_128593978 Show fit	0.56	ENST00000280333.6	DOCK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dedicator of cytokinesis 1
chr15_+_75182346 Show fit	0.53	ENST00000569931.1 ENST00000352410.4 ENST00000566377.1 ENST00000569233.1 ENST00000567132.1 ENST00000564633.1 ENST00000568907.1 ENST00000563422.1 ENST00000564003.1 ENST00000562800.1 ENST00000563786.1 ENST00000535694.1 ENST00000323744.6 ENST00000568828.1 ENST00000562606.1 ENST00000565576.1 ENST00000567570.1	MPI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mannose phosphate isomerase
chr20_-_39928705 Show fit	0.51	ENST00000436099.2 ENST00000309060.3 ENST00000373261.1 ENST00000436440.2 ENST00000540170.1 ENST00000557816.1 ENST00000560361.1	ZHX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc fingers and homeoboxes 3
chr22_-_30956746 Show fit	0.49	ENST00000437282.1 ENST00000447224.1 ENST00000427899.1 ENST00000406955.1 ENST00000452827.1	GAL3ST1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	galactose-3-O-sulfotransferase 1
chr7_+_18535786 Show fit	0.47	ENST00000406072.1	HDAC9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 9
chr3_+_5163905 Show fit	0.45	ENST00000256496.3 ENST00000419534.2	ARL8B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 8B
chr15_+_75074385 Show fit	0.39	ENST00000220003.9	CSK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	c-src tyrosine kinase
chr12_-_100378006 Show fit	0.39	ENST00000547776.2 ENST00000329257.7 ENST00000547010.1	ANKS1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat and sterile alpha motif domain containing 1B
chr18_-_19283649 Show fit	0.37	ENST00000584464.1 ENST00000578270.1	ABHD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	abhydrolase domain containing 3
chr22_+_22988816 Show fit	0.36	ENST00000480559.1 ENST00000448514.1	GGTLC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gamma-glutamyltransferase light chain 2
chr5_+_125758813 Show fit	0.35	ENST00000285689.3 ENST00000515200.1	GRAMD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GRAM domain containing 3
chr15_+_75074410 Show fit	0.31	ENST00000439220.2	CSK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	c-src tyrosine kinase
chr1_-_53163992 Show fit	0.29	ENST00000371538.3	SELRC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome c oxidase assembly factor 7
chr5_+_140762268 Show fit	0.27	ENST00000518325.1	PCDHGA7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin gamma subfamily A, 7
chr15_-_56535464 Show fit	0.27	ENST00000559447.2 ENST00000422057.1 ENST00000317318.6 ENST00000423270.1	RFX7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulatory factor X, 7
chr11_-_89653576 Show fit	0.24	ENST00000420869.1	TRIM49D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 49D1
chr7_+_39125365 Show fit	0.19	ENST00000559001.1 ENST00000464276.2	POU6F2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	POU class 6 homeobox 2
chr20_-_39928756 Show fit	0.18	ENST00000432768.2	ZHX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc fingers and homeoboxes 3
chr2_-_20850813 Show fit	0.18	ENST00000402541.1 ENST00000406618.3 ENST00000304031.3	HS1BP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HCLS1 binding protein 3
chr8_-_8751068 Show fit	0.17	ENST00000276282.6	MFHAS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	malignant fibrous histiocytoma amplified sequence 1
chr3_+_44626446 Show fit	0.16	ENST00000441021.1 ENST00000322734.2	ZNF660 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 660
chr12_-_18243075 Show fit	0.16	ENST00000536890.1	RERGL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RERG/RAS-like
chr1_+_152627927 Show fit	0.15	ENST00000444515.1 ENST00000536536.1	LINC00302 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 302
chr14_-_94759361 Show fit	0.14	ENST00000393096.1	SERPINA10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_94759595 Show fit	0.11	ENST00000261994.4	SERPINA10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr3_+_184032313 Show fit	0.09	ENST00000392537.2 ENST00000444134.1 ENST00000450424.1 ENST00000421110.1 ENST00000382330.3 ENST00000426123.1 ENST00000350481.5 ENST00000455679.1 ENST00000440448.1	EIF4G1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 4 gamma, 1
chr11_-_57158109 Show fit	0.07	ENST00000525955.1 ENST00000533605.1 ENST00000311862.5	PRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr6_-_30640811 Show fit	0.04	ENST00000376442.3	DHX16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr4_-_165305086 Show fit	0.02	ENST00000507270.1 ENST00000514618.1 ENST00000503008.1	MARCH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.7	35.1	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
6.5	25.8	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
3.7	11.0	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
3.6	10.9	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
3.2	9.5	GO:0014016	neuroblast differentiation(GO:0014016)
3.1	15.3	GO:1904636	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
3.0	17.8	GO:0007296	vitellogenesis(GO:0007296)
2.9	8.7	GO:0046098	guanine metabolic process(GO:0046098)
2.5	7.6	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
2.1	10.4	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.0	9.9	GO:0048478	replication fork protection(GO:0048478)
1.8	7.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
1.7	6.9	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
1.7	5.2	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.6	4.8	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
1.6	11.0	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
1.4	18.4	GO:0019388	galactose catabolic process(GO:0019388)
1.4	4.2	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.3	8.1	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
1.3	5.2	GO:0015808	L-alanine transport(GO:0015808)
1.2	3.7	GO:1903314	nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
1.2	16.3	GO:0051599	response to hydrostatic pressure(GO:0051599)
1.1	3.4	GO:1905166	negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
1.1	6.7	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
1.1	5.5	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.1	10.9	GO:0018202	peptidyl-histidine modification(GO:0018202)
1.1	14.9	GO:0010668	ectodermal cell differentiation(GO:0010668) nail development(GO:0035878)
0.9	4.3	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.8	2.5	GO:0061317	arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.8	8.4	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.8	12.5	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.8	8.3	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8	2.4	GO:0051685	maintenance of ER location(GO:0051685)
0.8	4.6	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.8	21.5	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.8	9.2	GO:0022417	protein maturation by protein folding(GO:0022417)
0.7	5.2	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.7	5.0	GO:0070294	renal sodium ion absorption(GO:0070294)
0.7	4.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.7	6.8	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.7	2.0	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.6	3.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.6	3.7	GO:0035709	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.6	3.5	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.4	4.8	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4	3.5	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.4	3.0	GO:0006751	glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4	8.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.3	6.5	GO:0002021	response to dietary excess(GO:0002021)
0.3	6.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.3	1.7	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3	4.3	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.3	3.6	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3	36.8	GO:0006903	vesicle targeting(GO:0006903)
0.3	5.1	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.3	2.5	GO:0015693	magnesium ion transport(GO:0015693)
0.3	8.4	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.3	5.1	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.3	10.1	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.3	0.8	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749) negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2	8.2	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.2	4.3	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.2	2.9	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2	23.1	GO:0032392	DNA geometric change(GO:0032392)
0.2	3.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2	3.1	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2	16.4	GO:0045454	cell redox homeostasis(GO:0045454)
0.2	1.3	GO:0036438	maintenance of lens transparency(GO:0036438)
0.2	2.5	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	3.6	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2	1.7	GO:0030322	stabilization of membrane potential(GO:0030322)
0.2	5.3	GO:0006270	DNA replication initiation(GO:0006270)
0.1	5.8	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.1	1.0	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.1	0.6	GO:0009822	alkaloid catabolic process(GO:0009822)
0.1	0.7	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	2.8	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	1.1	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.5	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	0.4	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	0.9	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.1	5.0	GO:0042407	cristae formation(GO:0042407)
0.1	3.3	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	4.6	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	0.7	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.2	GO:0048867	stem cell fate determination(GO:0048867)
0.1	2.6	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.1	4.0	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1	6.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.1	2.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	2.8	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1	2.2	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	0.9	GO:0008206	bile acid metabolic process(GO:0008206)
0.1	0.5	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.8	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1	2.2	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1	0.6	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	14.7	GO:0016042	lipid catabolic process(GO:0016042)
0.0	3.5	GO:0006611	protein export from nucleus(GO:0006611)
0.0	2.8	GO:0006915	apoptotic process(GO:0006915)
0.0	0.6	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	1.2	GO:0033006	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0	0.2	GO:0008218	bioluminescence(GO:0008218)
0.0	4.8	GO:0009408	response to heat(GO:0009408)
0.0	0.7	GO:0000154	rRNA modification(GO:0000154)
0.0	0.7	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	7.7	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0	1.7	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.6	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0	0.7	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.8	GO:0030195	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0	1.4	GO:0051028	mRNA transport(GO:0051028)
0.0	1.5	GO:0043473	pigmentation(GO:0043473)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.0	14.9	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
2.6	15.3	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
1.8	9.2	GO:1990425	ryanodine receptor complex(GO:1990425)
1.7	15.2	GO:0031298	replication fork protection complex(GO:0031298)
1.4	4.3	GO:0031372	UBC13-MMS2 complex(GO:0031372)
1.2	8.1	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.9	11.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.9	16.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.9	3.4	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.8	23.7	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.8	25.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.8	8.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.6	9.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.6	4.3	GO:0071203	WASH complex(GO:0071203)
0.6	4.8	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6	12.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.5	2.5	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5	16.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.5	6.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.5	3.3	GO:0061617	MICOS complex(GO:0061617)
0.4	5.1	GO:0030681	multimeric ribonuclease P complex(GO:0030681)
0.3	33.2	GO:0060170	ciliary membrane(GO:0060170)
0.3	4.5	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.3	3.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3	13.1	GO:0030131	clathrin adaptor complex(GO:0030131)
0.3	1.7	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.3	7.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.3	8.3	GO:0035371	microtubule plus-end(GO:0035371)
0.3	4.6	GO:0031932	TORC2 complex(GO:0031932)
0.2	4.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.2	4.6	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.2	1.7	GO:0001739	sex chromatin(GO:0001739)
0.2	3.6	GO:0031105	septin complex(GO:0031105)
0.2	2.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.2	2.8	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.2	11.3	GO:0072562	blood microparticle(GO:0072562)
0.2	8.7	GO:1990391	DNA repair complex(GO:1990391)
0.2	17.8	GO:0042734	presynaptic membrane(GO:0042734)
0.2	7.6	GO:0043034	costamere(GO:0043034)
0.2	17.1	GO:0005882	intermediate filament(GO:0005882)
0.2	2.6	GO:0030914	STAGA complex(GO:0030914)
0.2	12.5	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	2.8	GO:0097225	sperm midpiece(GO:0097225)
0.1	3.6	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	3.4	GO:0005682	U5 snRNP(GO:0005682)
0.1	6.8	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.1	10.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	5.0	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	3.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	5.5	GO:0045171	intercellular bridge(GO:0045171)
0.1	4.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	3.7	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	1.5	GO:0031082	BLOC complex(GO:0031082)
0.1	4.0	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	3.1	GO:0008180	COP9 signalosome(GO:0008180)
0.1	4.8	GO:0035580	specific granule lumen(GO:0035580)
0.0	6.3	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	8.0	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.9	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	2.9	GO:0030424	axon(GO:0030424)
0.0	19.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	2.3	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	2.6	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	1.3	GO:0001772	immunological synapse(GO:0001772)
0.0	1.0	GO:0043198	dendritic shaft(GO:0043198)
0.0	1.2	GO:0043025	neuronal cell body(GO:0043025)
0.0	2.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	55.0	GO:0070062	extracellular exosome(GO:0070062)
0.0	1.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.1	GO:0005884	actin filament(GO:0005884)
0.0	0.6	GO:0031672	A band(GO:0031672)
0.0	0.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.8	GO:0031225	anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.7	35.1	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
7.9	39.6	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
7.2	21.5	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
6.1	18.4	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
5.2	25.8	GO:0043023	ribosomal large subunit binding(GO:0043023)
3.6	10.9	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
2.9	8.7	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
2.4	9.5	GO:0003990	acetylcholinesterase activity(GO:0003990)
1.7	10.4	GO:0004167	dopachrome isomerase activity(GO:0004167)
1.7	5.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.7	11.9	GO:0004673	protein histidine kinase activity(GO:0004673)
1.7	6.7	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.4	11.0	GO:0016842	amidine-lyase activity(GO:0016842)
1.3	5.2	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.2	3.7	GO:1902122	chenodeoxycholic acid binding(GO:1902122)
1.2	7.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.2	8.1	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.1	14.9	GO:0038132	neuregulin binding(GO:0038132)
1.1	3.4	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
1.0	5.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
1.0	11.0	GO:0097016	L27 domain binding(GO:0097016)
0.9	25.5	GO:0000400	four-way junction DNA binding(GO:0000400)
0.9	10.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.8	2.5	GO:0000150	recombinase activity(GO:0000150)
0.8	16.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7	11.5	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.7	17.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.7	3.5	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.7	9.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.6	3.7	GO:0023025	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.6	8.4	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.6	7.6	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.6	8.1	GO:0016594	glycine binding(GO:0016594)
0.6	3.4	GO:1903135	cupric ion binding(GO:1903135)
0.5	2.2	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.5	11.3	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.5	2.5	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.5	2.9	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4	15.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3	1.0	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3	5.0	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3	5.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.3	5.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.3	8.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.3	2.5	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3	12.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.2	1.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.2	4.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	4.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.2	4.6	GO:0070300	phosphatidic acid binding(GO:0070300)
0.2	4.8	GO:0030955	potassium ion binding(GO:0030955)
0.2	8.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.2	6.8	GO:0005123	death receptor binding(GO:0005123)
0.2	3.0	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.2	0.6	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	16.3	GO:0097110	scaffold protein binding(GO:0097110)
0.2	0.8	GO:0009378	four-way junction helicase activity(GO:0009378)
0.2	2.0	GO:0048406	nerve growth factor binding(GO:0048406)
0.2	3.1	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2	1.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2	1.7	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.2	5.8	GO:0015248	sterol transporter activity(GO:0015248)
0.1	0.6	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.1	3.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	2.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	2.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	4.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	5.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	0.4	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	0.5	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	0.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.9	GO:0032052	bile acid binding(GO:0032052)
0.1	1.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	2.4	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	5.4	GO:0000149	SNARE binding(GO:0000149)
0.0	2.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.5	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	18.4	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0	0.6	GO:0070330	aromatase activity(GO:0070330)
0.0	1.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.7	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	7.3	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	7.9	GO:0045296	cadherin binding(GO:0045296)
0.0	1.5	GO:0004386	helicase activity(GO:0004386)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	18.0	GO:0042802	identical protein binding(GO:0042802)
0.0	0.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	42.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.6	14.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.6	15.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5	9.2	PID ALK2 PATHWAY	ALK2 signaling events
0.5	11.9	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	17.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3	6.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	14.1	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.2	10.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	11.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.2	11.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.2	6.9	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	9.5	PID ATR PATHWAY	ATR signaling pathway
0.2	11.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	7.4	PID AURORA A PATHWAY	Aurora A signaling
0.1	4.6	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	3.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	5.2	PID E2F PATHWAY	E2F transcription factor network
0.1	2.6	PID MYC PATHWAY	C-MYC pathway
0.1	2.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	3.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	13.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8	35.1	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.7	11.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.7	23.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.6	9.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5	8.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4	11.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.4	10.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.4	4.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.4	9.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	2.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3	11.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3	19.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.3	6.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	1.7	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	3.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	8.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.2	16.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	6.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	2.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	4.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.2	3.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	7.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.1	5.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	5.3	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	11.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	5.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	3.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	4.6	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.1	4.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	2.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	2.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	5.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	4.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	10.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.9	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	5.2	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	4.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	9.5	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.0	3.0	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	1.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.0	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	2.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	7.2	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	5.8	REACTOME TRANSLATION	Genes involved in Translation
0.0	4.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism