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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HIVEP1

Z-value: 1.97

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Transcription factors associated with HIVEP1

Gene Symbol Gene ID Gene Info
ENSG00000095951.12 HIVEP zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIVEP1hg19_v2_chr6_+_12012536_120125710.063.5e-01Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_32605195 47.63 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr6_+_32709119 34.13 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr22_+_22930626 31.15 ENST00000390302.2
immunoglobulin lambda variable 2-33 (non-functional)
chr6_+_32407619 29.00 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr14_-_106322288 26.02 ENST00000390559.2
immunoglobulin heavy constant mu
chr6_+_32605134 25.50 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr17_+_40440481 24.75 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr5_-_149792295 24.56 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_+_29691198 24.50 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr14_-_35873856 23.89 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr6_-_31324943 23.69 ENST00000412585.2
ENST00000434333.1
major histocompatibility complex, class I, B
chr6_+_31554962 23.53 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
leukocyte specific transcript 1
chr6_+_29691056 23.33 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
major histocompatibility complex, class I, F
chr6_-_31239846 22.61 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
major histocompatibility complex, class I, C
chr7_-_150497406 21.65 ENST00000492607.1
ENST00000326442.5
ENST00000450753.2
transmembrane protein 176B
chr12_-_9913489 21.57 ENST00000228434.3
ENST00000536709.1
CD69 molecule
chr6_-_32908792 21.03 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr6_+_31555045 21.00 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr14_-_107049312 20.64 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr22_-_37640277 20.34 ENST00000401529.3
ENST00000249071.6
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_+_29910301 19.58 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr13_-_46756351 19.11 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_150497621 18.96 ENST00000434545.1
transmembrane protein 176B
chr19_-_10445399 18.62 ENST00000592945.1
intercellular adhesion molecule 3
chr12_+_7055631 18.58 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chrX_-_107019181 18.49 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr7_+_150497569 18.01 ENST00000004103.3
transmembrane protein 176A
chr22_+_37257015 17.15 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
neutrophil cytosolic factor 4, 40kDa
chr16_+_33605231 17.10 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr17_-_62097927 16.79 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr2_+_61108771 16.77 ENST00000394479.3
v-rel avian reticuloendotheliosis viral oncogene homolog
chr14_-_106866934 16.68 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr19_-_2042065 15.97 ENST00000591588.1
ENST00000591142.1
MAP kinase interacting serine/threonine kinase 2
chr2_-_43453734 14.93 ENST00000282388.3
ZFP36 ring finger protein-like 2
chr2_+_61108650 14.90 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr6_+_138188551 14.81 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chr6_+_31554826 14.76 ENST00000376089.2
ENST00000396112.2
leukocyte specific transcript 1
chr6_+_31554779 14.05 ENST00000376090.2
leukocyte specific transcript 1
chr22_-_37640456 14.02 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr17_-_62097904 13.37 ENST00000583366.1
intercellular adhesion molecule 2
chr2_+_10183651 13.33 ENST00000305883.1
Kruppel-like factor 11
chr14_-_106573756 13.00 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr7_+_150497491 12.96 ENST00000484928.1
transmembrane protein 176A
chr6_-_31704282 12.31 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr7_+_30960915 11.79 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr2_+_89999259 11.77 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr14_-_106926724 11.60 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr11_-_64510409 11.39 ENST00000394429.1
ENST00000394428.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_56970567 10.94 ENST00000563911.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr17_-_62084241 10.93 ENST00000449662.2
intercellular adhesion molecule 2
chr1_+_212738676 10.54 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr5_-_39219705 10.12 ENST00000351578.6
FYN binding protein
chr3_-_58196939 9.87 ENST00000394549.2
ENST00000461914.3
deoxyribonuclease I-like 3
chr17_-_34207295 9.81 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr14_-_106845789 9.27 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr14_-_106518922 9.27 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr12_-_14721283 9.20 ENST00000240617.5
phospholipase B domain containing 1
chr16_+_32077386 9.19 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr1_-_236030216 8.96 ENST00000389794.3
ENST00000389793.2
lysosomal trafficking regulator
chr14_-_106725723 8.62 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr15_+_85923856 8.51 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
A kinase (PRKA) anchor protein 13
chr11_-_5271122 8.51 ENST00000330597.3
hemoglobin, gamma A
chr5_-_150460914 8.50 ENST00000389378.2
TNFAIP3 interacting protein 1
chr14_-_107114267 8.46 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr11_-_67276100 8.41 ENST00000301488.3
cyclin-dependent kinase 2 associated protein 2
chr14_+_75988851 8.39 ENST00000555504.1
basic leucine zipper transcription factor, ATF-like
chr3_-_58196688 8.34 ENST00000486455.1
deoxyribonuclease I-like 3
chr2_+_97481974 7.68 ENST00000377060.3
ENST00000305510.3
cyclin M3
chr2_-_157189180 7.67 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
nuclear receptor subfamily 4, group A, member 2
chr3_-_49142178 7.59 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
glutaminyl-tRNA synthetase
chr11_+_121447469 7.58 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr8_-_101321584 7.57 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr6_+_31554456 7.40 ENST00000339530.4
leukocyte specific transcript 1
chr16_+_33020496 7.39 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr4_+_155484155 7.31 ENST00000509493.1
fibrinogen beta chain
chr5_+_40679584 7.08 ENST00000302472.3
prostaglandin E receptor 4 (subtype EP4)
chr15_+_74908147 6.98 ENST00000568139.1
ENST00000563297.1
ENST00000568488.1
ENST00000352989.5
ENST00000348245.3
CDC-like kinase 3
chr13_-_46964177 6.90 ENST00000389908.3
KIAA0226-like
chr14_+_103589789 6.85 ENST00000558056.1
ENST00000560869.1
tumor necrosis factor, alpha-induced protein 2
chr5_-_150460539 6.81 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNFAIP3 interacting protein 1
chr5_-_39219641 6.73 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chr17_-_39093672 6.63 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
keratin 23 (histone deacetylase inducible)
chr7_+_30951461 6.59 ENST00000311813.4
aquaporin 1 (Colton blood group)
chr12_+_112451120 6.40 ENST00000261735.3
ENST00000455836.1
endoplasmic reticulum protein 29
chr7_-_99097863 6.35 ENST00000426306.2
ENST00000337673.6
zinc finger protein 394
chr19_-_40336969 6.26 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
fibrillarin
chr1_-_202129105 6.19 ENST00000367279.4
protein tyrosine phosphatase, non-receptor type 7
chr8_+_27168988 6.17 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
protein tyrosine kinase 2 beta
chr1_-_40041925 6.14 ENST00000372862.3
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr7_+_107110488 6.13 ENST00000304402.4
G protein-coupled receptor 22
chr6_-_112115074 6.12 ENST00000368667.2
FYN oncogene related to SRC, FGR, YES
chr17_+_7461781 6.11 ENST00000349228.4
tumor necrosis factor (ligand) superfamily, member 13
chr12_+_10658201 6.08 ENST00000322446.3
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr1_+_111770278 6.06 ENST00000369748.4
chitinase 3-like 2
chr1_-_40042073 6.04 ENST00000372858.3
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr10_+_114133773 5.99 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr4_+_155484103 5.85 ENST00000302068.4
fibrinogen beta chain
chr17_+_43209967 5.82 ENST00000431281.1
ENST00000591859.1
acyl-CoA binding domain containing 4
chr1_-_159893507 5.81 ENST00000368096.1
transgelin 2
chr1_+_111770232 5.78 ENST00000369744.2
chitinase 3-like 2
chr16_-_33647696 5.77 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein
chr11_+_65190245 5.68 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr1_+_156123359 5.68 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr17_-_40897043 5.59 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
enhancer of zeste homolog 1 (Drosophila)
chr3_-_49131013 5.55 ENST00000424300.1
glutamine-rich 1
chr1_+_156123318 5.54 ENST00000368285.3
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_+_31554612 5.46 ENST00000211921.7
leukocyte specific transcript 1
chr10_+_129705299 5.44 ENST00000254667.3
protein tyrosine phosphatase, receptor type, E
chr18_+_21083437 5.41 ENST00000269221.3
ENST00000590868.1
ENST00000592119.1
chromosome 18 open reading frame 8
chr22_-_50964849 5.24 ENST00000543927.1
ENST00000423348.1
SCO2 cytochrome c oxidase assembly protein
chr12_-_14133053 5.24 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr17_-_46623441 5.23 ENST00000330070.4
homeobox B2
chr16_-_11681316 5.16 ENST00000571688.1
lipopolysaccharide-induced TNF factor
chr1_-_47069955 5.14 ENST00000341183.5
ENST00000496619.1
MAP kinase interacting serine/threonine kinase 1
chr16_+_33006369 5.11 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr3_+_9773409 5.08 ENST00000433861.2
ENST00000424362.1
ENST00000383829.2
ENST00000302054.3
ENST00000420291.1
bromodomain and PHD finger containing, 1
chr13_+_30002846 5.05 ENST00000542829.1
microtubule associated tumor suppressor candidate 2
chr1_-_200379129 5.04 ENST00000367353.1
zinc finger protein 281
chr13_+_28712614 5.04 ENST00000380958.3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr11_-_3862206 4.97 ENST00000351018.4
ras homolog family member G
chr16_+_32063311 4.93 ENST00000426099.1
AC142381.1
chr12_-_113909877 4.92 ENST00000261731.3
LIM homeobox 5
chr14_-_106586656 4.84 ENST00000390602.2
immunoglobulin heavy variable 3-13
chr19_-_55770311 4.83 ENST00000412770.2
protein phosphatase 6, regulatory subunit 1
chr22_-_29949680 4.82 ENST00000397873.2
ENST00000490103.1
THO complex 5
chr10_-_125851961 4.75 ENST00000346248.5
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr15_+_91427642 4.74 ENST00000328850.3
ENST00000414248.2
feline sarcoma oncogene
chrX_-_73072534 4.71 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr16_-_20556492 4.71 ENST00000568098.1
acyl-CoA synthetase medium-chain family member 2B
chr12_+_52445191 4.69 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4, group A, member 1
chr9_-_116837249 4.67 ENST00000466610.2
alpha-1-microglobulin/bikunin precursor
chr6_+_31554636 4.67 ENST00000433492.1
leukocyte specific transcript 1
chr5_+_49962495 4.62 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr1_+_46640750 4.61 ENST00000372003.1
tetraspanin 1
chr17_-_26876350 4.53 ENST00000470125.1
unc-119 homolog (C. elegans)
chr19_-_5978090 4.52 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RAN binding protein 3
chr4_-_109087872 4.48 ENST00000510624.1
lymphoid enhancer-binding factor 1
chr11_+_116700614 4.41 ENST00000375345.1
apolipoprotein C-III
chr17_-_48943706 4.32 ENST00000499247.2
transducer of ERBB2, 1
chr3_-_101232019 4.30 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr7_+_73442102 4.27 ENST00000445912.1
ENST00000252034.7
elastin
chr1_+_221051699 4.26 ENST00000366903.6
H2.0-like homeobox
chr6_-_27440460 4.24 ENST00000377419.1
zinc finger protein 184
chr14_-_106622419 4.22 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr9_-_123691047 4.21 ENST00000373887.3
TNF receptor-associated factor 1
chr16_+_72088376 4.20 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr1_+_37940153 4.17 ENST00000373087.6
zinc finger CCCH-type containing 12A
chr1_-_47069886 4.10 ENST00000371946.4
ENST00000371945.4
ENST00000428112.2
ENST00000529170.1
MAP kinase interacting serine/threonine kinase 1
chr11_+_116700600 4.09 ENST00000227667.3
apolipoprotein C-III
chr12_-_113772835 4.07 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr10_+_20105157 4.05 ENST00000377242.3
ENST00000377252.4
plexin domain containing 2
chr12_-_57504069 4.04 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
signal transducer and activator of transcription 6, interleukin-4 induced
chr15_+_45003675 4.04 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
beta-2-microglobulin
chr21_+_34775698 4.00 ENST00000381995.1
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_+_37793318 3.87 ENST00000336308.5
StAR-related lipid transfer (START) domain containing 3
chr15_+_91427691 3.78 ENST00000559355.1
ENST00000394302.1
feline sarcoma oncogene
chr2_-_100721178 3.77 ENST00000409236.2
AF4/FMR2 family, member 3
chr5_+_142149955 3.75 ENST00000378004.3
Rho GTPase activating protein 26
chr2_-_88427568 3.73 ENST00000393750.3
ENST00000295834.3
fatty acid binding protein 1, liver
chr7_+_73442422 3.72 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
elastin
chr11_+_75526212 3.70 ENST00000356136.3
UV radiation resistance associated
chr1_+_221054584 3.70 ENST00000549319.1
H2.0-like homeobox
chr1_+_54359854 3.65 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
deiodinase, iodothyronine, type I
chr9_+_82187487 3.64 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_-_77712477 3.60 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chr17_+_37793378 3.58 ENST00000544210.2
ENST00000581894.1
ENST00000394250.4
ENST00000579479.1
ENST00000577248.1
ENST00000580611.1
StAR-related lipid transfer (START) domain containing 3
chr11_+_71846748 3.58 ENST00000445078.2
folate receptor 3 (gamma)
chr10_+_81838792 3.57 ENST00000372273.3
transmembrane protein 254
chr4_-_109087906 3.56 ENST00000515500.1
lymphoid enhancer-binding factor 1
chr1_+_114522049 3.55 ENST00000369551.1
ENST00000320334.4
olfactomedin-like 3
chr3_+_52821841 3.54 ENST00000405128.3
inter-alpha-trypsin inhibitor heavy chain 1
chr7_-_8301768 3.52 ENST00000265577.7
islet cell autoantigen 1, 69kDa
chr6_+_33176265 3.48 ENST00000374656.4
ring finger protein 1
chr19_-_51522955 3.47 ENST00000358789.3
kallikrein-related peptidase 10
chr1_-_200379180 3.44 ENST00000294740.3
zinc finger protein 281
chr11_-_46142615 3.43 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr17_+_21191341 3.39 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr1_-_6259641 3.38 ENST00000234875.4
ribosomal protein L22
chr9_+_82187630 3.37 ENST00000265284.6
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr15_-_55700216 3.34 ENST00000569205.1
cell cycle progression 1
chr19_+_17326191 3.33 ENST00000595101.1
ENST00000596136.1
ENST00000379776.4
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr7_-_8302207 3.24 ENST00000407906.1
islet cell autoantigen 1, 69kDa
chr6_-_35656685 3.23 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr3_+_186383741 3.20 ENST00000232003.4
histidine-rich glycoprotein
chr7_+_73442457 3.18 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
elastin
chr15_+_91411810 3.12 ENST00000268171.3
furin (paired basic amino acid cleaving enzyme)
chr21_+_34775772 3.12 ENST00000405436.1
interferon gamma receptor 2 (interferon gamma transducer 1)
chr11_+_71846764 3.11 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
folate receptor 3 (gamma)
chr7_+_73442487 3.11 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
elastin
chr9_+_82188077 3.08 ENST00000425506.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_-_43484718 3.04 ENST00000372422.2
Yip1 domain family, member 3
chr1_-_169599314 3.04 ENST00000367786.2
ENST00000458599.2
ENST00000367795.2
ENST00000263686.6
selectin P (granule membrane protein 140kDa, antigen CD62)
chr1_-_160231451 3.04 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr7_-_8301682 3.00 ENST00000396675.3
ENST00000430867.1
islet cell autoantigen 1, 69kDa
chr11_-_119999611 2.98 ENST00000529044.1
tripartite motif containing 29
chr11_+_118754475 2.98 ENST00000292174.4
chemokine (C-X-C motif) receptor 5
chrX_+_149737046 2.96 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
myotubularin 1
chr11_-_119999539 2.91 ENST00000541857.1
tripartite motif containing 29
chr19_-_52133588 2.86 ENST00000570106.2
sialic acid binding Ig-like lectin 5
chr11_+_58910201 2.85 ENST00000528737.1
family with sequence similarity 111, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.5 50.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
11.8 117.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
6.5 38.7 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
6.2 24.7 GO:0000255 allantoin metabolic process(GO:0000255)
6.1 18.4 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
5.5 71.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
5.1 15.3 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
4.9 24.6 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
4.6 18.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
3.5 10.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
3.1 34.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
3.0 9.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
2.8 8.5 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
2.8 8.5 GO:2000910 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
2.7 19.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
2.7 34.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
2.6 7.7 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
2.5 7.6 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
2.5 7.6 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.5 9.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.4 7.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
2.3 18.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
1.8 14.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
1.8 125.0 GO:0006910 phagocytosis, recognition(GO:0006910)
1.7 5.2 GO:0021569 rhombomere 3 development(GO:0021569)
1.7 8.4 GO:2000035 regulation of stem cell division(GO:2000035)
1.6 8.0 GO:0071895 odontoblast differentiation(GO:0071895)
1.6 3.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.6 6.4 GO:0043335 protein unfolding(GO:0043335)
1.6 6.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.5 6.2 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
1.4 4.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.3 4.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.3 8.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.3 13.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.2 3.7 GO:0051684 maintenance of Golgi location(GO:0051684)
1.2 2.3 GO:0071288 cellular response to mercury ion(GO:0071288)
1.1 4.5 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.1 10.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
1.1 11.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.1 18.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
1.1 19.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.0 3.1 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
1.0 91.1 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
1.0 4.9 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
1.0 1.9 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.0 116.2 GO:0031295 T cell costimulation(GO:0031295)
1.0 7.7 GO:0046898 response to cycloheximide(GO:0046898)
0.9 3.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.9 11.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.8 7.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.8 8.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.8 5.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.8 3.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.8 2.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.7 3.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.7 1.4 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.7 13.2 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.7 2.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.7 4.7 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.7 3.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.7 5.9 GO:0060215 primitive hemopoiesis(GO:0060215)
0.6 4.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.6 1.9 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.6 6.9 GO:0051601 exocyst localization(GO:0051601)
0.6 1.8 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.6 60.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.6 3.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.6 2.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.6 5.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.6 8.5 GO:0015671 oxygen transport(GO:0015671)
0.6 1.7 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.6 9.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.6 17.1 GO:0045730 respiratory burst(GO:0045730)
0.5 9.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.5 4.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 8.2 GO:0042832 defense response to protozoan(GO:0042832)
0.5 2.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.4 1.3 GO:0052314 serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.4 6.7 GO:0015884 folic acid transport(GO:0015884)
0.4 1.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.4 4.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.4 3.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.4 1.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.4 2.0 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.4 7.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.4 1.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.4 3.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 3.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 15.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 2.5 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 4.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 4.3 GO:1902373 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) negative regulation of mRNA catabolic process(GO:1902373)
0.3 5.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.3 46.5 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.3 0.9 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.3 1.0 GO:0006408 snRNA export from nucleus(GO:0006408)
0.2 1.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.7 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 28.4 GO:0002377 immunoglobulin production(GO:0002377)
0.2 1.9 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 3.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.2 1.8 GO:0015693 magnesium ion transport(GO:0015693)
0.2 7.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 10.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.2 7.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 1.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 5.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 2.0 GO:0021670 lateral ventricle development(GO:0021670)
0.2 5.0 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.2 0.3 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.2 1.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 1.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.2 2.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 2.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 1.2 GO:0051262 protein tetramerization(GO:0051262)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.9 GO:0090131 mesenchyme migration(GO:0090131)
0.1 1.5 GO:0060013 righting reflex(GO:0060013)
0.1 1.4 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.1 3.0 GO:0061157 mRNA destabilization(GO:0061157)
0.1 0.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.8 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 10.2 GO:0035690 cellular response to drug(GO:0035690)
0.1 3.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 5.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 4.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.1 2.1 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 2.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 1.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 2.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.5 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.1 2.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 10.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.7 GO:0032328 alanine transport(GO:0032328)
0.1 2.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 2.1 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.6 GO:0019098 reproductive behavior(GO:0019098) maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 5.4 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 3.2 GO:1903393 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.1 0.2 GO:0060437 lung growth(GO:0060437)
0.1 2.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 1.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 2.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 2.5 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 3.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 2.2 GO:0098743 cell aggregation(GO:0098743)
0.1 0.5 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 3.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.1 GO:0007265 Ras protein signal transduction(GO:0007265)
0.1 3.7 GO:0001510 RNA methylation(GO:0001510)
0.1 2.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.6 GO:2000811 negative regulation of anoikis(GO:2000811)
0.1 1.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.4 GO:0048478 replication fork protection(GO:0048478)
0.1 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.6 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 2.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 4.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 2.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 6.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 2.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 3.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 2.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 2.8 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 2.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.5 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 1.2 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.6 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 6.0 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 2.2 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 2.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 3.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.3 GO:0030449 regulation of complement activation(GO:0030449)
0.0 5.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 5.0 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 2.3 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.8 GO:0032570 response to progesterone(GO:0032570)
0.0 1.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.9 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 1.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0007631 feeding behavior(GO:0007631)
0.0 1.3 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 1.8 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 1.7 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.6 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.7 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.9 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.2 GO:0002021 response to dietary excess(GO:0002021)
0.0 1.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 1.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 1.7 GO:0007162 negative regulation of cell adhesion(GO:0007162)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 117.8 GO:0042612 MHC class I protein complex(GO:0042612)
8.7 181.8 GO:0042611 MHC protein complex(GO:0042611)
6.1 18.4 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
4.8 57.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
3.5 10.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
2.5 125.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
2.1 17.1 GO:0032010 phagolysosome(GO:0032010)
2.1 6.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
1.8 10.9 GO:1990037 Lewy body core(GO:1990037)
1.8 41.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.7 18.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.7 5.0 GO:0031251 PAN complex(GO:0031251)
1.4 14.3 GO:0071953 elastic fiber(GO:0071953)
1.1 8.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.1 12.6 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
1.1 4.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.0 19.1 GO:0001891 phagocytic cup(GO:0001891)
0.8 5.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.8 11.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.7 7.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.7 8.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.7 8.5 GO:0005833 hemoglobin complex(GO:0005833)
0.7 4.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.7 8.3 GO:0005577 fibrinogen complex(GO:0005577)
0.7 2.0 GO:0005879 axonemal microtubule(GO:0005879)
0.6 7.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.6 4.1 GO:0030061 mitochondrial crista(GO:0030061)
0.5 5.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.5 7.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 27.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.4 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.4 7.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 2.5 GO:0097165 nuclear stress granule(GO:0097165)
0.3 5.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 3.5 GO:0001739 sex chromatin(GO:0001739)
0.3 2.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 2.2 GO:1990635 proximal dendrite(GO:1990635)
0.3 6.9 GO:0000145 exocyst(GO:0000145)
0.3 1.2 GO:0045160 myosin I complex(GO:0045160)
0.3 2.4 GO:0045179 apical cortex(GO:0045179)
0.3 4.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 2.0 GO:0060091 kinocilium(GO:0060091)
0.3 3.7 GO:0030897 HOPS complex(GO:0030897)
0.3 45.9 GO:0072562 blood microparticle(GO:0072562)
0.3 16.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 2.0 GO:0072687 meiotic spindle(GO:0072687)
0.2 1.0 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.2 4.3 GO:0005861 troponin complex(GO:0005861)
0.2 1.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 4.5 GO:0051233 spindle midzone(GO:0051233)
0.1 2.1 GO:0036038 MKS complex(GO:0036038)
0.1 2.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 11.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 8.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 42.8 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 3.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 8.4 GO:0035580 specific granule lumen(GO:0035580)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 2.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.5 GO:0032040 small-subunit processome(GO:0032040)
0.1 4.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 20.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 2.3 GO:0005685 U1 snRNP(GO:0005685)
0.1 8.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 63.9 GO:0000139 Golgi membrane(GO:0000139)
0.1 1.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 5.5 GO:0030175 filopodium(GO:0030175)
0.1 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 3.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 7.7 GO:0016605 PML body(GO:0016605)
0.1 3.4 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 13.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.4 GO:0015030 Cajal body(GO:0015030)
0.1 2.0 GO:0016592 mediator complex(GO:0016592)
0.1 1.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 4.7 GO:0005925 focal adhesion(GO:0005925)
0.0 1.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 3.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 5.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 16.8 GO:0005615 extracellular space(GO:0005615)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 3.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0030133 transport vesicle(GO:0030133)
0.0 4.3 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.7 GO:0034358 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 7.9 GO:0005813 centrosome(GO:0005813)
0.0 7.3 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 136.2 GO:0032395 MHC class II receptor activity(GO:0032395)
8.0 47.8 GO:0046979 TAP2 binding(GO:0046979)
6.1 24.6 GO:0042289 MHC class II protein binding(GO:0042289)
6.1 18.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
4.1 12.2 GO:0017130 poly(C) RNA binding(GO:0017130)
2.7 65.9 GO:0042605 peptide antigen binding(GO:0042605)
2.5 7.6 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
2.4 133.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
2.1 8.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.1 6.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
2.1 18.5 GO:0043426 MRF binding(GO:0043426)
1.7 5.2 GO:0042806 fucose binding(GO:0042806)
1.7 17.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.5 14.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.4 7.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.4 9.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.4 25.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.2 3.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.2 19.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.2 4.7 GO:0019862 IgA binding(GO:0019862)
1.1 11.8 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
1.0 6.1 GO:0042610 CD8 receptor binding(GO:0042610)
1.0 5.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
1.0 1.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.9 24.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.9 7.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.9 5.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.8 21.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.8 4.7 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.8 8.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.7 3.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.7 4.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.7 8.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.7 7.7 GO:0051434 BH3 domain binding(GO:0051434)
0.7 4.2 GO:0030492 hemoglobin binding(GO:0030492)
0.7 2.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.7 33.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.7 11.2 GO:0038191 neuropilin binding(GO:0038191)
0.6 11.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.6 23.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.6 3.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 3.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 62.6 GO:0003823 antigen binding(GO:0003823)
0.5 4.7 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.5 1.9 GO:0038181 bile acid receptor activity(GO:0038181)
0.5 5.2 GO:0004645 phosphorylase activity(GO:0004645)
0.5 7.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.5 8.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 2.3 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.5 4.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 1.8 GO:0008384 IkappaB kinase activity(GO:0008384)
0.4 6.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.4 11.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.4 4.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.4 15.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.4 6.7 GO:0005542 folic acid binding(GO:0005542)
0.4 7.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.3 1.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 6.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 18.4 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.3 2.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 5.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 7.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 2.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 3.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.3 1.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 1.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 7.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 3.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 1.6 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.3 2.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 5.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 10.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 3.0 GO:0019215 intermediate filament binding(GO:0019215)
0.2 1.6 GO:0034235 GPI anchor binding(GO:0034235)
0.2 4.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 2.6 GO:0031014 troponin T binding(GO:0031014)
0.2 2.9 GO:0031996 thioesterase binding(GO:0031996)
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.9 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 2.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 3.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 29.2 GO:0005178 integrin binding(GO:0005178)
0.2 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 36.7 GO:0019887 protein kinase regulator activity(GO:0019887)
0.1 3.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 4.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 21.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 5.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 5.2 GO:0050699 WW domain binding(GO:0050699)
0.1 0.5 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.9 GO:0048156 tau protein binding(GO:0048156)
0.1 0.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 5.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.6 GO:0043422 protein kinase B binding(GO:0043422)
0.1 3.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 4.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 5.8 GO:0046332 SMAD binding(GO:0046332)
0.1 2.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 4.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 3.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 20.3 GO:0051015 actin filament binding(GO:0051015)
0.1 0.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 4.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 4.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 2.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 4.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.8 GO:0015026 coreceptor activity(GO:0015026)
0.1 2.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 7.6 GO:0044325 ion channel binding(GO:0044325)
0.1 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 19.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 3.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 4.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 4.3 GO:0000149 SNARE binding(GO:0000149)
0.0 7.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.8 GO:0001047 core promoter binding(GO:0001047)
0.0 5.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 14.1 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 23.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
1.5 56.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
1.4 72.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.3 24.7 PID IL5 PATHWAY IL5-mediated signaling events
0.8 83.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.8 38.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.7 25.6 PID CD40 PATHWAY CD40/CD40L signaling
0.5 27.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.5 6.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 6.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 3.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 15.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 9.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 8.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 1.4 PID IL27 PATHWAY IL27-mediated signaling events
0.2 10.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 2.4 PID EPO PATHWAY EPO signaling pathway
0.2 2.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 4.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 9.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 8.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 10.5 PID AP1 PATHWAY AP-1 transcription factor network
0.1 4.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.5 ST ADRENERGIC Adrenergic Pathway
0.1 10.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 19.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.9 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.0 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 3.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target  Total log-likelihood Term Description
11.8 117.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
4.7 107.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
2.1 18.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
1.7 25.7 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
1.5 20.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.2 24.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.9 45.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.8 13.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.7 23.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.7 57.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.7 21.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.6 7.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.6 9.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.6 3.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.5 8.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 2.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.5 9.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.5 9.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 8.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 14.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.4 7.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 15.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3 3.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 7.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.3 40.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation