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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXB2_UNCX_HOXD3

Z-value: 1.28

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Transcription factors associated with HOXB2_UNCX_HOXD3

Gene Symbol Gene ID Gene Info
ENSG00000173917.9 homeobox B2
ENSG00000164853.8 UNC homeobox
ENSG00000128652.7 homeobox D3

Activity-expression correlation:

Activity profile of HOXB2_UNCX_HOXD3 motif

Sorted Z-values of HOXB2_UNCX_HOXD3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_41593425 26.79 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr2_-_136678123 26.17 ENST00000422708.1
aspartyl-tRNA synthetase
chr3_-_141747950 23.29 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr6_-_32157947 22.02 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr12_+_28410128 20.90 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr2_-_61697862 20.72 ENST00000398571.2
ubiquitin specific peptidase 34
chr17_+_48823975 20.12 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr1_-_89357179 19.27 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr12_+_104337515 19.14 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr15_-_55562479 18.82 ENST00000564609.1
RAB27A, member RAS oncogene family
chr2_-_225434538 18.45 ENST00000409096.1
cullin 3
chr15_-_55563072 18.12 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr3_-_69129501 17.34 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
ubiquitin-like modifier activating enzyme 3
chr12_-_15103621 16.50 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr10_+_94451574 16.30 ENST00000492654.2
hematopoietically expressed homeobox
chr7_+_77428149 16.10 ENST00000415251.2
ENST00000275575.7
putative homeodomain transcription factor 2
chr13_-_46716969 16.09 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_32908792 15.36 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr12_-_118628350 15.14 ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr1_-_149900122 14.96 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr16_-_66864806 14.89 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NEDD8 activating enzyme E1 subunit 1
chr5_-_10761206 14.71 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr15_-_55562582 14.38 ENST00000396307.2
RAB27A, member RAS oncogene family
chr4_+_40198527 14.30 ENST00000381799.5
ras homolog family member H
chr10_+_13652047 14.27 ENST00000601460.1
Uncharacterized protein
chr4_-_103749179 13.90 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr15_+_80351910 13.83 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6
chr20_+_30327063 13.77 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr3_-_49066811 13.69 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr7_-_25268104 13.46 ENST00000222674.2
neuropeptide VF precursor
chr18_-_33702078 13.14 ENST00000586829.1
solute carrier family 39 (zinc transporter), member 6
chr13_+_37581115 13.08 ENST00000481013.1
exosome component 8
chr4_+_174089904 13.07 ENST00000265000.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_+_174844645 12.52 ENST00000486220.1
RAB GTPase activating protein 1-like
chr5_-_148929848 12.43 ENST00000504676.1
ENST00000515435.1
casein kinase 1, alpha 1
chr2_-_158300556 11.97 ENST00000264192.3
cytohesin 1 interacting protein
chr5_+_159848807 11.69 ENST00000352433.5
pituitary tumor-transforming 1
chr4_-_103749205 11.54 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr7_+_77428066 11.54 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr2_+_90248739 11.51 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr1_+_236958554 11.50 ENST00000366577.5
ENST00000418145.2
5-methyltetrahydrofolate-homocysteine methyltransferase
chr6_-_31508304 11.44 ENST00000376177.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chrX_-_118986911 11.41 ENST00000276201.2
ENST00000345865.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr6_-_36515177 11.18 ENST00000229812.7
serine/threonine kinase 38
chr18_-_33709268 11.10 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr8_-_49833978 10.97 ENST00000020945.1
snail family zinc finger 2
chr6_-_38670897 10.95 ENST00000373365.4
glyoxalase I
chr4_-_83280767 10.93 ENST00000514671.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr4_-_143227088 10.83 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr15_+_75080883 10.78 ENST00000567571.1
c-src tyrosine kinase
chr4_-_105416039 10.64 ENST00000394767.2
CXXC finger protein 4
chr8_-_109260897 10.62 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr9_+_12693336 10.53 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr1_+_68150744 10.47 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr2_-_89327228 10.44 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr5_+_115177178 10.26 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr11_-_104972158 10.21 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr3_+_37035289 10.14 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
mutL homolog 1
chr9_+_36572851 10.04 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chr8_-_101963482 9.86 ENST00000419477.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_-_87856280 9.83 ENST00000490437.1
ENST00000431660.1
sorcin
chr2_-_89513402 9.76 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr16_+_12059091 9.66 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr16_+_33605231 9.62 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr6_+_26365443 9.59 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr2_+_109204743 9.52 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr7_-_87856303 9.44 ENST00000394641.3
sorcin
chr13_-_95131923 9.42 ENST00000377028.5
ENST00000446125.1
dopachrome tautomerase
chr2_-_10587897 9.41 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr8_-_101963677 9.34 ENST00000395956.3
ENST00000395953.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr19_-_10446449 9.34 ENST00000592439.1
intercellular adhesion molecule 3
chr7_-_54826920 9.24 ENST00000395535.3
ENST00000352861.4
Sec61 gamma subunit
chr12_+_20963647 9.15 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr6_-_109702885 9.14 ENST00000504373.1
CD164 molecule, sialomucin
chr14_+_39583427 9.11 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chrX_-_109590174 9.09 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr1_+_53480598 9.01 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr2_+_102456277 8.84 ENST00000421882.1
mitogen-activated protein kinase kinase kinase kinase 4
chr6_+_32938692 8.75 ENST00000443797.2
bromodomain containing 2
chr5_-_43557791 8.73 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr10_+_81272287 8.54 ENST00000520547.2
eukaryotic translation initiation factor 5A-like 1
chr11_-_14521379 8.46 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
coatomer protein complex, subunit beta 1
chr2_+_109237717 8.41 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr16_-_46655538 8.40 ENST00000303383.3
SHC SH2-domain binding protein 1
chr4_+_169013666 8.38 ENST00000359299.3
annexin A10
chr12_+_20963632 8.29 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr20_-_5107180 8.26 ENST00000379160.3
proliferating cell nuclear antigen
chr8_-_49834299 8.25 ENST00000396822.1
snail family zinc finger 2
chr5_-_134735568 8.24 ENST00000510038.1
ENST00000304332.4
H2A histone family, member Y
chr9_-_128246769 8.24 ENST00000444226.1
mitogen-activated protein kinase associated protein 1
chrX_+_19373700 8.20 ENST00000379804.1
pyruvate dehydrogenase (lipoamide) alpha 1
chr8_+_55047763 8.18 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr14_-_20801427 8.14 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr8_-_42234745 8.09 ENST00000220812.2
dickkopf WNT signaling pathway inhibitor 4
chr3_+_130569429 8.08 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr12_-_76477707 8.08 ENST00000551992.1
nucleosome assembly protein 1-like 1
chr7_+_141438118 8.03 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
single-stranded DNA binding protein 1, mitochondrial
chr12_-_56694142 7.93 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chr11_-_104827425 7.90 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr5_-_180670370 7.81 ENST00000502844.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_+_155658849 7.76 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
death associated protein 3
chr17_-_30228678 7.69 ENST00000261708.4
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr17_-_39191107 7.66 ENST00000344363.5
keratin associated protein 1-3
chr4_-_84035905 7.62 ENST00000311507.4
placenta-specific 8
chr16_-_58585513 7.48 ENST00000245138.4
ENST00000567285.1
CCR4-NOT transcription complex, subunit 1
chr2_-_89568263 7.43 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr20_+_25388293 7.40 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr14_+_35761580 7.38 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr3_-_185641681 7.38 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr4_-_103749313 7.37 ENST00000394803.5
ubiquitin-conjugating enzyme E2D 3
chr2_-_89292422 7.36 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr12_+_69979210 7.22 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr2_+_90060377 7.18 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr11_-_104905840 7.16 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr1_+_198608146 7.14 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr8_+_22424551 7.13 ENST00000523348.1
sorbin and SH3 domain containing 3
chr12_-_14133053 7.07 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr21_-_30445886 7.05 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
chaperonin containing TCP1, subunit 8 (theta)
chr4_-_84035868 7.00 ENST00000426923.2
ENST00000509973.1
placenta-specific 8
chr8_-_27695552 6.96 ENST00000522944.1
ENST00000301905.4
PDZ binding kinase
chr8_-_102216925 6.90 ENST00000517844.1
zinc finger protein 706
chr2_-_55496174 6.88 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
mitochondrial translational initiation factor 2
chr12_-_54653313 6.84 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr4_-_143226979 6.81 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_103746924 6.79 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr1_+_38478378 6.77 ENST00000373014.4
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr4_+_113568207 6.71 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr1_-_75198940 6.65 ENST00000417775.1
crystallin, zeta (quinone reductase)
chr1_+_74701062 6.64 ENST00000326637.3
TNNI3 interacting kinase
chr2_-_89340242 6.64 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr5_+_44809027 6.62 ENST00000507110.1
mitochondrial ribosomal protein S30
chr16_+_12059050 6.57 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr2_-_136873735 6.54 ENST00000409817.1
chemokine (C-X-C motif) receptor 4
chr2_-_55496344 6.51 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr11_+_5710919 6.49 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr6_+_32938665 6.48 ENST00000374831.4
ENST00000395289.2
bromodomain containing 2
chr2_+_89952792 6.47 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr4_-_103746683 6.41 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr18_+_3247779 6.41 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr16_-_24942273 6.39 ENST00000571406.1
Rho GTPase activating protein 17
chr4_-_103749105 6.39 ENST00000394801.4
ENST00000394804.2
ubiquitin-conjugating enzyme E2D 3
chr14_-_21737551 6.37 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr1_-_54411255 6.35 ENST00000371377.3
heat shock protein family B (small), member 11
chr2_-_89459813 6.30 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr1_-_159893507 6.28 ENST00000368096.1
transgelin 2
chr7_+_107224364 6.25 ENST00000491150.1
B-cell receptor-associated protein 29
chr8_-_80942061 6.21 ENST00000519386.1
mitochondrial ribosomal protein S28
chr5_+_167913450 6.19 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr4_-_39979576 6.19 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr12_+_10658201 6.16 ENST00000322446.3
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr9_+_125132803 6.14 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_68961905 6.11 ENST00000295381.3
Rho GTPase activating protein 25
chr16_+_69345243 6.09 ENST00000254950.11
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr5_-_140700322 6.09 ENST00000313368.5
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr16_+_85645007 6.08 ENST00000405402.2
Gse1 coiled-coil protein
chrX_-_110655306 6.05 ENST00000371993.2
doublecortin
chr1_+_62901968 6.05 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
ubiquitin specific peptidase 1
chr10_-_48416849 6.03 ENST00000249598.1
growth differentiation factor 2
chr8_-_90996459 6.00 ENST00000517337.1
ENST00000409330.1
nibrin
chr1_-_28527152 5.97 ENST00000321830.5
Uncharacterized protein
chr3_+_139063372 5.92 ENST00000478464.1
mitochondrial ribosomal protein S22
chr4_-_66536057 5.88 ENST00000273854.3
EPH receptor A5
chr7_-_54826869 5.88 ENST00000450622.1
Sec61 gamma subunit
chr4_+_147096837 5.87 ENST00000296581.5
ENST00000502781.1
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_+_56078695 5.84 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr16_+_57279004 5.82 ENST00000219204.3
ADP-ribosylation factor-like 2 binding protein
chr2_-_89442621 5.81 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr15_+_58430567 5.79 ENST00000536493.1
aquaporin 9
chr19_-_14945933 5.78 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr7_+_115862858 5.74 ENST00000393481.2
testis derived transcript (3 LIM domains)
chr7_-_22862406 5.72 ENST00000372879.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr18_-_47018897 5.72 ENST00000418495.1
ribosomal protein L17
chr5_-_142780280 5.68 ENST00000424646.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_-_150444116 5.68 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr8_-_101718991 5.67 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr18_-_3219847 5.67 ENST00000261606.7
myomesin 1
chr12_-_25055177 5.65 ENST00000538118.1
branched chain amino-acid transaminase 1, cytosolic
chr17_+_45728427 5.62 ENST00000540627.1
karyopherin (importin) beta 1
chr5_+_135394840 5.61 ENST00000503087.1
transforming growth factor, beta-induced, 68kDa
chr4_-_103747011 5.60 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr2_+_90153696 5.59 ENST00000417279.2
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr6_+_139456226 5.58 ENST00000367658.2
headcase homolog (Drosophila)
chr2_-_176046391 5.57 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr6_+_24775153 5.57 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr3_-_108248169 5.56 ENST00000273353.3
myosin, heavy chain 15
chr1_-_197115818 5.55 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr6_+_32407619 5.53 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr5_+_140602904 5.53 ENST00000515856.2
ENST00000239449.4
protocadherin beta 14
chr11_+_101983176 5.50 ENST00000524575.1
Yes-associated protein 1
chrX_-_153602991 5.49 ENST00000369850.3
ENST00000422373.1
filamin A, alpha
chr9_+_108463234 5.46 ENST00000374688.1
transmembrane protein 38B
chr15_+_41624892 5.45 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
nucleolar and spindle associated protein 1
chr12_+_69979113 5.45 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr20_+_35807512 5.44 ENST00000373622.5
ribophorin II
chr1_-_153518270 5.42 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chrX_-_20236970 5.42 ENST00000379548.4
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_+_52456327 5.41 ENST00000556760.1
chromosome 14 open reading frame 166
chr3_+_158519654 5.41 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr11_-_72070206 5.37 ENST00000544382.1
ClpB caseinolytic peptidase B homolog (E. coli)
chr11_-_47664072 5.35 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
mitochondrial carrier 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB2_UNCX_HOXD3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 55.9 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
8.7 26.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
6.4 19.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
5.8 17.3 GO:0007113 endomitotic cell cycle(GO:0007113)
5.4 16.3 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
5.1 20.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
4.6 18.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
4.3 17.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
4.2 12.7 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
4.1 16.5 GO:0071461 cellular response to redox state(GO:0071461)
3.6 10.9 GO:1901355 response to rapamycin(GO:1901355)
3.6 3.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
3.4 10.1 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
3.3 13.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
3.2 19.3 GO:1904798 positive regulation of core promoter binding(GO:1904798)
3.0 14.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.8 19.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.7 8.2 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
2.6 20.4 GO:0032790 ribosome disassembly(GO:0032790)
2.5 5.0 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
2.4 24.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
2.4 9.4 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
2.3 13.7 GO:0006177 GMP biosynthetic process(GO:0006177)
2.2 10.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
2.1 8.3 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
2.1 6.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
2.0 6.1 GO:0090611 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
2.0 14.0 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
2.0 7.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
2.0 9.8 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
1.9 5.8 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.9 5.8 GO:0070666 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
1.9 13.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.9 7.5 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
1.8 7.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.8 1.8 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
1.8 5.5 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
1.8 9.0 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.8 3.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.8 12.4 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
1.8 10.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
1.8 21.0 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
1.7 10.5 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
1.7 20.9 GO:0090160 Golgi to lysosome transport(GO:0090160)
1.7 1.7 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
1.7 5.1 GO:2000653 regulation of genetic imprinting(GO:2000653) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
1.6 9.7 GO:1901419 regulation of response to alcohol(GO:1901419)
1.6 3.2 GO:0046098 guanine metabolic process(GO:0046098)
1.6 11.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.5 13.9 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.5 7.6 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.5 4.6 GO:0061009 common bile duct development(GO:0061009)
1.5 9.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.5 13.5 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
1.5 4.5 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.5 7.4 GO:1902904 late endosomal microautophagy(GO:0061738) clathrin coat disassembly(GO:0072318) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.5 22.0 GO:0090168 Golgi reassembly(GO:0090168)
1.5 1.5 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.5 66.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.4 5.7 GO:0048496 maintenance of organ identity(GO:0048496)
1.4 7.1 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
1.4 11.3 GO:1902969 mitotic DNA replication(GO:1902969)
1.4 5.6 GO:0031291 Ran protein signal transduction(GO:0031291)
1.4 5.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
1.4 5.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.4 4.2 GO:0061743 motor learning(GO:0061743)
1.4 4.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
1.4 8.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.4 6.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
1.4 8.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
1.3 8.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
1.3 9.4 GO:0021847 ventricular zone neuroblast division(GO:0021847)
1.3 4.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
1.3 3.9 GO:1990523 bone regeneration(GO:1990523)
1.3 7.6 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
1.3 5.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
1.3 5.0 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
1.3 5.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
1.2 6.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.2 23.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.2 15.9 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
1.2 3.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
1.2 11.9 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
1.2 10.6 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.2 10.5 GO:0070986 left/right axis specification(GO:0070986)
1.2 2.3 GO:0035822 gene conversion(GO:0035822)
1.1 12.6 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
1.1 3.4 GO:0043418 homocysteine catabolic process(GO:0043418)
1.1 31.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
1.1 5.5 GO:0051661 maintenance of centrosome location(GO:0051661)
1.1 4.4 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.1 11.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
1.1 2.2 GO:0003162 atrioventricular node development(GO:0003162)
1.1 9.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.1 4.3 GO:0035616 maintenance of DNA methylation(GO:0010216) histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.1 4.3 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
1.1 3.2 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.1 7.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.1 15.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.1 8.5 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.0 3.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.0 3.1 GO:0071030 generation of catalytic spliceosome for second transesterification step(GO:0000350) nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
1.0 8.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.0 4.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.0 20.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.0 6.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.0 3.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.0 5.8 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.9 9.1 GO:0042262 DNA protection(GO:0042262)
0.9 3.6 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.9 8.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.9 5.2 GO:0071233 cellular response to leucine(GO:0071233)
0.9 2.6 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.8 0.8 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.8 1.6 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.8 3.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.8 2.4 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.8 14.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.8 2.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.8 4.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.8 2.4 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.8 0.8 GO:0071046 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.8 2.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.8 5.6 GO:0051026 chiasma assembly(GO:0051026)
0.8 5.5 GO:0048368 lateral mesoderm development(GO:0048368)
0.8 0.8 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.8 4.7 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.8 18.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.8 4.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.7 1.5 GO:0001302 replicative cell aging(GO:0001302)
0.7 3.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.7 2.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.7 25.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 2.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.7 5.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.7 3.5 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.7 10.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.7 7.0 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.7 2.8 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.7 4.9 GO:0070487 monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.7 4.9 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.7 2.1 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.7 6.9 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.7 2.8 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.7 5.5 GO:0015846 polyamine transport(GO:0015846)
0.7 12.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.7 2.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.7 4.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.7 0.7 GO:0032632 interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.7 2.0 GO:0019417 sulfur oxidation(GO:0019417)
0.7 3.3 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.7 3.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.7 9.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.7 3.9 GO:0060613 fat pad development(GO:0060613)
0.7 19.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.7 2.0 GO:0003186 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186)
0.6 2.6 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.6 10.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.6 3.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.6 1.9 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.6 46.5 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.6 95.3 GO:0002377 immunoglobulin production(GO:0002377)
0.6 2.5 GO:0043248 proteasome assembly(GO:0043248)
0.6 1.9 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.6 21.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.6 11.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.6 1.8 GO:0051697 protein delipidation(GO:0051697)
0.6 0.6 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.6 1.8 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 7.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.6 14.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.6 2.9 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.6 10.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 2.8 GO:0006574 valine catabolic process(GO:0006574)
0.6 1.7 GO:0050821 protein stabilization(GO:0050821)
0.6 1.7 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.6 2.2 GO:1901029 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.6 19.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.6 1.7 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.5 1.6 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.5 4.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.5 2.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.5 1.6 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.5 2.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.5 5.1 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.5 2.0 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.5 2.0 GO:0071699 olfactory placode formation(GO:0030910) endocardium formation(GO:0060214) positive regulation of sarcomere organization(GO:0060298) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) regulation of forebrain neuron differentiation(GO:2000977)
0.5 4.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.5 2.5 GO:0007386 compartment pattern specification(GO:0007386)
0.5 2.0 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5 2.9 GO:0048254 snoRNA localization(GO:0048254)
0.5 1.4 GO:1901993 meiotic cell cycle phase transition(GO:0044771) establishment of meiotic spindle localization(GO:0051295) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.5 4.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.5 12.1 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.5 3.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.5 0.9 GO:0002384 hepatic immune response(GO:0002384)
0.5 16.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.4 2.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.4 1.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.4 2.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.4 3.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.4 1.7 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.4 5.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.4 2.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.4 2.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 3.4 GO:0015816 glycine transport(GO:0015816)
0.4 4.2 GO:0051382 kinetochore assembly(GO:0051382)
0.4 4.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.4 20.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.4 12.5 GO:0045143 homologous chromosome segregation(GO:0045143)
0.4 3.6 GO:0015886 heme transport(GO:0015886)
0.4 6.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.4 3.2 GO:0048733 sebaceous gland development(GO:0048733)
0.4 0.8 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.4 15.2 GO:0048255 mRNA stabilization(GO:0048255)
0.4 19.5 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.4 1.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 1.9 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.4 4.9 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.4 14.7 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.4 2.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.4 4.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.4 4.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.4 1.5 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.4 4.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.4 1.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.4 1.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.4 83.6 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.4 1.1 GO:0048318 axial mesoderm development(GO:0048318)
0.4 3.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.4 5.7 GO:0000338 protein deneddylation(GO:0000338)
0.4 1.1 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.4 2.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.4 7.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.4 21.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.4 7.4 GO:0019985 translesion synthesis(GO:0019985)
0.4 0.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.3 2.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 15.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.3 1.0 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.3 7.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.3 3.0 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.3 31.6 GO:0051225 spindle assembly(GO:0051225)
0.3 1.0 GO:0045896 regulation of transcription during mitosis(GO:0045896)
0.3 0.7 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.3 1.9 GO:0051451 myoblast migration(GO:0051451)
0.3 1.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.3 1.0 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 1.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.3 3.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.3 6.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 0.9 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.3 2.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 3.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.3 4.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 3.2 GO:0009642 response to light intensity(GO:0009642)
0.3 1.2 GO:0021759 globus pallidus development(GO:0021759)
0.3 6.6 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.3 1.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 5.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.3 0.6 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.3 8.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 4.8 GO:0006020 inositol metabolic process(GO:0006020)
0.3 5.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 6.5 GO:0000154 rRNA modification(GO:0000154)
0.3 39.5 GO:0045047 protein targeting to ER(GO:0045047)
0.3 4.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 1.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.3 5.0 GO:0006012 galactose metabolic process(GO:0006012)
0.3 32.7 GO:0006334 nucleosome assembly(GO:0006334)
0.3 15.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.3 3.7 GO:0016180 snRNA processing(GO:0016180)
0.3 1.6 GO:0006013 mannose metabolic process(GO:0006013)
0.3 10.4 GO:0016266 O-glycan processing(GO:0016266)
0.3 2.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 1.0 GO:0002456 T cell mediated immunity(GO:0002456)
0.3 0.5 GO:1901652 response to peptide(GO:1901652)
0.3 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 0.5 GO:0022615 protein to membrane docking(GO:0022615)
0.2 12.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 5.6 GO:0043066 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069)
0.2 2.2 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212)
0.2 11.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 1.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 5.4 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.2 10.8 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2 2.3 GO:0007512 adult heart development(GO:0007512)
0.2 3.8 GO:0007018 microtubule-based movement(GO:0007018)
0.2 4.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 2.5 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.3 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.2 0.9 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 4.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 0.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 0.8 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 0.8 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.2 1.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 5.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 1.0 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.2 1.9 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 0.8 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.2 0.8 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 9.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 1.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 6.3 GO:0006414 translational elongation(GO:0006414)
0.2 1.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 0.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 4.4 GO:0007635 chemosensory behavior(GO:0007635)
0.2 2.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.2 1.1 GO:0033189 response to vitamin A(GO:0033189)
0.2 1.6 GO:0030091 protein repair(GO:0030091)
0.2 1.1 GO:0043486 histone exchange(GO:0043486)
0.2 13.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 4.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.4 GO:0051601 exocyst localization(GO:0051601)
0.2 1.9 GO:0030903 notochord development(GO:0030903)
0.2 0.5 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 1.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 1.9 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 2.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 8.7 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.2 3.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 0.7 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.2 5.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 1.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 3.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 2.4 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.6 GO:0006298 mismatch repair(GO:0006298)
0.2 1.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 20.7 GO:0031424 keratinization(GO:0031424)
0.2 1.0 GO:0030953 astral microtubule organization(GO:0030953)
0.2 0.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 5.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 3.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 1.9 GO:0070071 proton-transporting V-type ATPase complex assembly(GO:0070070) proton-transporting two-sector ATPase complex assembly(GO:0070071) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 14.0 GO:0006413 translational initiation(GO:0006413)
0.1 1.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 2.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 3.0 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 0.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 2.5 GO:0051412 response to corticosterone(GO:0051412)
0.1 0.7 GO:0097186 amelogenesis(GO:0097186)
0.1 3.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.1 0.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 3.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.4 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.3 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 4.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 3.3 GO:0006825 copper ion transport(GO:0006825)
0.1 2.2 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.7 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.6 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.1 1.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.6 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.6 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 1.8 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.5 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 3.4 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 2.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.0 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 2.4 GO:0009303 rRNA transcription(GO:0009303)
0.1 6.5 GO:0034644 cellular response to UV(GO:0034644)
0.1 2.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 3.8 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 1.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 2.4 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.1 3.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:0043010 camera-type eye development(GO:0043010)
0.1 1.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.6 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 1.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 5.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 8.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.3 GO:0060117 auditory receptor cell development(GO:0060117)
0.1 0.6 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.4 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 6.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 2.4 GO:0010659 cardiac muscle cell apoptotic process(GO:0010659)
0.1 2.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 4.3 GO:0061351 neural precursor cell proliferation(GO:0061351)
0.1 2.2 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.6 GO:0050890 cognition(GO:0050890)
0.1 0.5 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 0.7 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.6 GO:0046717 acid secretion(GO:0046717)
0.1 0.6 GO:0046519 sphingoid metabolic process(GO:0046519)
0.1 3.3 GO:0021762 substantia nigra development(GO:0021762)
0.1 3.0 GO:0031295 T cell costimulation(GO:0031295)
0.1 2.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.5 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 15.0 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 1.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.1 2.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.1 0.9 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.8 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.1 1.5 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.5 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 1.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 2.0 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 0.3 GO:0007097 nuclear migration(GO:0007097)
0.1 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920) positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 1.2 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 0.3 GO:0070305 response to cGMP(GO:0070305)
0.1 0.8 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 1.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) endocardial cushion to mesenchymal transition(GO:0090500)
0.0 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.3 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.6 GO:2000573 positive regulation of DNA biosynthetic process(GO:2000573)
0.0 0.5 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 1.2 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 1.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 1.7 GO:0031016 pancreas development(GO:0031016)
0.0 1.8 GO:0007498 mesoderm development(GO:0007498)
0.0 1.3 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 2.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 3.0 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 1.2 GO:0048477 oogenesis(GO:0048477)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.8 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.6 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 1.0 GO:0008380 RNA splicing(GO:0008380)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.5 GO:0006402 mRNA catabolic process(GO:0006402)
0.0 0.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.0 GO:0048840 otolith development(GO:0048840)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 30.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
4.2 75.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
3.4 10.1 GO:0005715 late recombination nodule(GO:0005715)
3.0 3.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
2.9 2.9 GO:0005687 U4 snRNP(GO:0005687)
2.8 19.5 GO:0044326 dendritic spine neck(GO:0044326)
2.8 8.3 GO:0070557 PCNA-p21 complex(GO:0070557)
2.3 9.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
2.2 8.8 GO:0000811 GINS complex(GO:0000811)
2.0 18.4 GO:0005827 polar microtubule(GO:0005827)
1.9 5.8 GO:0071746 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
1.9 38.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.8 5.5 GO:0031523 Myb complex(GO:0031523)
1.8 19.3 GO:0005688 U6 snRNP(GO:0005688)
1.7 5.0 GO:0033565 ESCRT-0 complex(GO:0033565)
1.6 18.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.5 19.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.5 7.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.5 13.4 GO:0070652 HAUS complex(GO:0070652)
1.4 5.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.4 8.2 GO:0001740 Barr body(GO:0001740)
1.3 3.9 GO:0044530 supraspliceosomal complex(GO:0044530)
1.3 13.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.2 5.0 GO:0035838 growing cell tip(GO:0035838)
1.2 14.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.2 5.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
1.1 13.8 GO:0043203 axon hillock(GO:0043203)
1.1 11.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.1 4.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
1.1 7.9 GO:0030870 Mre11 complex(GO:0030870)
1.1 4.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.1 18.9 GO:0034719 SMN-Sm protein complex(GO:0034719)
1.1 6.6 GO:0070435 Shc-EGFR complex(GO:0070435)
1.1 7.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
1.0 3.1 GO:0071020 post-spliceosomal complex(GO:0071020)
1.0 3.0 GO:0034657 GID complex(GO:0034657)
1.0 4.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.0 20.6 GO:0042613 MHC class II protein complex(GO:0042613)
1.0 2.9 GO:0002139 stereocilia coupling link(GO:0002139)
1.0 4.9 GO:0005726 perichromatin fibrils(GO:0005726)
1.0 11.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 18.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.9 10.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.9 25.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.9 18.5 GO:0001891 phagocytic cup(GO:0001891)
0.9 24.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.9 13.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.9 2.6 GO:0005588 collagen type V trimer(GO:0005588)
0.8 8.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.8 4.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.8 3.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.8 19.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.8 5.3 GO:0036449 microtubule minus-end(GO:0036449)
0.7 7.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.7 5.2 GO:0032982 myosin filament(GO:0032982)
0.7 7.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.7 24.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.7 13.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 10.7 GO:0090543 Flemming body(GO:0090543)
0.7 1.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.7 2.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.7 8.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.7 4.1 GO:1990037 Lewy body core(GO:1990037)
0.7 2.0 GO:0031905 early endosome lumen(GO:0031905)
0.7 4.7 GO:0036021 endolysosome lumen(GO:0036021)
0.7 9.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.7 4.6 GO:0031415 NatA complex(GO:0031415)
0.6 2.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.6 1.9 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
0.6 3.8 GO:0008537 proteasome activator complex(GO:0008537)
0.6 3.1 GO:0033503 HULC complex(GO:0033503)
0.6 2.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 6.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.6 1.8 GO:1990752 microtubule end(GO:1990752)
0.6 3.0 GO:0071986 Ragulator complex(GO:0071986)
0.6 4.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.6 5.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.6 4.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 8.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 2.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.5 25.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 2.2 GO:0035061 interchromatin granule(GO:0035061)
0.5 6.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.5 3.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.5 30.1 GO:0001772 immunological synapse(GO:0001772)
0.5 3.6 GO:0070852 cell body fiber(GO:0070852)
0.5 22.1 GO:0045095 keratin filament(GO:0045095)
0.5 5.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 1.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.5 4.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.5 2.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 8.2 GO:0031932 TORC2 complex(GO:0031932)
0.5 4.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.5 5.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 2.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 1.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 60.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 12.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 3.7 GO:0032039 integrator complex(GO:0032039)
0.4 11.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.4 9.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.4 1.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 10.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.4 3.0 GO:0070187 telosome(GO:0070187)
0.4 3.0 GO:0042382 paraspeckles(GO:0042382)
0.4 8.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 8.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 3.3 GO:0034709 methylosome(GO:0034709)
0.4 4.7 GO:0032433 filopodium tip(GO:0032433)
0.3 1.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 5.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 33.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 2.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 1.6 GO:0032389 MutLalpha complex(GO:0032389)
0.3 5.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 3.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 6.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 1.2 GO:0032280 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.3 10.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 0.9 GO:0005607 laminin-2 complex(GO:0005607)
0.3 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 4.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.3 3.8 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 2.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.3 0.8 GO:0097679 other organism cytoplasm(GO:0097679)
0.3 4.2 GO:0000242 pericentriolar material(GO:0000242)
0.3 4.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 9.9 GO:0005876 spindle microtubule(GO:0005876)
0.2 3.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 6.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 4.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 12.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 4.9 GO:0071564 npBAF complex(GO:0071564)
0.2 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 3.8 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.2 11.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 5.6 GO:0032420 stereocilium(GO:0032420)
0.2 3.9 GO:0005838 proteasome regulatory particle(GO:0005838)
0.2 2.7 GO:0097227 sperm annulus(GO:0097227)
0.2 0.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 2.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 0.5 GO:0005902 microvillus(GO:0005902)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 18.6 GO:0005840 ribosome(GO:0005840)
0.2 5.8 GO:0032993 protein-DNA complex(GO:0032993)
0.2 0.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.2 0.8 GO:0060091 kinocilium(GO:0060091)
0.2 2.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.2 14.2 GO:0072562 blood microparticle(GO:0072562)
0.2 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 3.7 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 0.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 16.6 GO:0005643 nuclear pore(GO:0005643)
0.2 1.4 GO:0000125 PCAF complex(GO:0000125)
0.2 1.1 GO:0000812 Swr1 complex(GO:0000812)
0.1 11.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 1.9 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 20.1 GO:0005681 spliceosomal complex(GO:0005681)
0.1 4.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 51.0 GO:0016607 nuclear speck(GO:0016607)
0.1 2.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 3.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 6.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0098576 lumenal side of membrane(GO:0098576)
0.1 1.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 9.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.7 GO:0032010 phagolysosome(GO:0032010)
0.1 5.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 3.6 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.1 7.9 GO:0005882 intermediate filament(GO:0005882)
0.1 2.4 GO:0043231 intracellular membrane-bounded organelle(GO:0043231)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 8.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 16.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 8.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 35.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 9.1 GO:0016605 PML body(GO:0016605)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.0 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 5.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.8 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.2 GO:0000791 euchromatin(GO:0000791)
0.1 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.4 GO:0032991 macromolecular complex(GO:0032991)
0.1 6.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 19.3 GO:0005769 early endosome(GO:0005769)
0.1 17.5 GO:0000785 chromatin(GO:0000785)
0.1 0.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 1.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.5 GO:0030139 endocytic vesicle(GO:0030139)
0.1 4.6 GO:0035579 specific granule membrane(GO:0035579)
0.1 14.8 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.1 1.4 GO:0042581 specific granule(GO:0042581)
0.0 3.0 GO:0005776 autophagosome(GO:0005776)
0.0 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005795 Golgi stack(GO:0005795)
0.0 1.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 8.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 5.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 4.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.0 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 43.6 GO:0005654 nucleoplasm(GO:0005654)
0.0 1.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.0 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.6 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
4.6 18.4 GO:0031208 POZ domain binding(GO:0031208)
3.5 17.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
3.4 13.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
3.0 9.0 GO:0070538 oleic acid binding(GO:0070538)
2.8 13.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.6 10.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
2.5 32.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
2.5 9.8 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.4 9.8 GO:0015265 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
2.4 14.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
2.3 14.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.2 30.5 GO:0050700 CARD domain binding(GO:0050700)
2.1 55.2 GO:0031489 myosin V binding(GO:0031489)
2.1 8.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
2.1 22.7 GO:0046790 virion binding(GO:0046790)
2.1 6.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
2.0 14.3 GO:0030621 U4 snRNA binding(GO:0030621)
1.9 5.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.9 1.9 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.7 10.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.7 5.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
1.6 16.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.6 7.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.6 9.4 GO:0004167 dopachrome isomerase activity(GO:0004167)
1.5 6.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.5 15.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.5 9.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.5 66.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.5 4.5 GO:0004802 transketolase activity(GO:0004802)
1.5 8.9 GO:0015266 protein channel activity(GO:0015266)
1.5 1.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.4 5.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.4 10.9 GO:0019237 centromeric DNA binding(GO:0019237)
1.4 16.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
1.3 22.7 GO:0008494 translation activator activity(GO:0008494)
1.3 4.0 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
1.3 6.5 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
1.3 24.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.3 10.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
1.2 4.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.2 17.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.2 13.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
1.2 37.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
1.2 3.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.2 8.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.1 5.7 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
1.1 3.3 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
1.1 8.8 GO:0004111 creatine kinase activity(GO:0004111)
1.1 6.6 GO:0048408 epidermal growth factor binding(GO:0048408)
1.1 3.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.1 8.6 GO:0008172 S-methyltransferase activity(GO:0008172)
1.1 10.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.1 3.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.0 3.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.0 5.0 GO:0001849 complement component C1q binding(GO:0001849)
1.0 5.8 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.0 3.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.0 4.8 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.9 15.9 GO:0003680 AT DNA binding(GO:0003680)
0.9 8.2 GO:0000182 rDNA binding(GO:0000182)
0.9 12.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.9 19.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.9 2.6 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.8 13.4 GO:0070513 death domain binding(GO:0070513)
0.8 5.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.8 12.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.8 3.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.8 10.6 GO:0016594 glycine binding(GO:0016594)
0.8 2.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.7 4.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.7 7.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.7 3.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.7 147.7 GO:0003823 antigen binding(GO:0003823)
0.7 1.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.7 2.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.7 3.6 GO:0000405 bubble DNA binding(GO:0000405)
0.7 10.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.7 24.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.7 25.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.7 3.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.6 2.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.6 5.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.6 2.6 GO:0016160 amylase activity(GO:0016160)
0.6 1.9 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.6 1.8 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.6 1.8 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.6 6.6 GO:0031013 troponin I binding(GO:0031013)
0.6 3.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.6 16.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.6 14.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.6 6.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 23.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 36.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.6 1.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.6 6.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.6 1.7 GO:0015616 DNA translocase activity(GO:0015616)
0.6 2.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6 1.7 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.6 2.3 GO:0008431 vitamin E binding(GO:0008431)
0.6 3.4 GO:0005499 vitamin D binding(GO:0005499)
0.6 3.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.6 11.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.5 1.6 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.5 3.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.5 11.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 2.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.5 1.6 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.5 4.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.5 3.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.5 3.0 GO:0008097 5S rRNA binding(GO:0008097)
0.5 21.4 GO:0004532 exoribonuclease activity(GO:0004532)
0.5 6.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.5 1.9 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.5 42.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.5 1.4 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.5 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 2.3 GO:0070728 leucine binding(GO:0070728)
0.5 3.6 GO:0004064 arylesterase activity(GO:0004064)
0.4 11.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 3.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 1.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.4 2.6 GO:0051870 methotrexate binding(GO:0051870)
0.4 1.3 GO:0033149 FFAT motif binding(GO:0033149)
0.4 1.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.4 7.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 4.0 GO:0004312 fatty acid synthase activity(GO:0004312)
0.4 9.2 GO:0030515 snoRNA binding(GO:0030515)
0.4 2.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 1.6 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 1.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.4 11.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 10.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 13.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 1.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.4 1.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.4 0.7 GO:0046977 peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.4 3.6 GO:0015232 heme transporter activity(GO:0015232)
0.4 4.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 1.0 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.3 11.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 5.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 2.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 3.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.3 1.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 2.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 12.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 1.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 68.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 1.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.3 4.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 3.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 2.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 0.9 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.3 5.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 1.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.3 0.6 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.3 7.4 GO:0017166 vinculin binding(GO:0017166)
0.3 7.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.3 2.0 GO:0008142 oxysterol binding(GO:0008142)
0.3 2.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.3 1.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 0.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.3 9.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 1.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.9 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 1.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.3 5.6 GO:0004697 protein kinase C activity(GO:0004697)
0.3 0.8 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 7.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.9 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 5.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 4.1 GO:0070410 co-SMAD binding(GO:0070410)
0.2 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 8.6 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2 3.8 GO:0070628 proteasome binding(GO:0070628)
0.2 5.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 9.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 1.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 15.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 1.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 0.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 6.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 5.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 3.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 7.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 5.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.0 GO:1990254 keratin filament binding(GO:1990254)
0.2 1.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 1.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.2 5.8 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 5.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 8.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.3 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 0.9 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 8.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 2.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.2 1.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 11.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 2.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.7 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 1.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 0.5 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 4.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 14.5 GO:0008565 protein transporter activity(GO:0008565)
0.2 8.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 2.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.3 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.2 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 95.1 GO:0008134 transcription factor binding(GO:0008134)
0.2 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 6.5 GO:0042169 SH2 domain binding(GO:0042169)
0.2 0.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 1.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.9 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 1.8 GO:0019213 deacetylase activity(GO:0019213)
0.2 2.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 1.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 35.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 3.1 GO:0043022 ribosome binding(GO:0043022)
0.1 3.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 6.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 11.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 7.2 GO:0005507 copper ion binding(GO:0005507)
0.1 22.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 2.7 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.1 1.9 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 15.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.6 GO:0008252 nucleotidase activity(GO:0008252)
0.1 2.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 10.8 GO:0001047 core promoter binding(GO:0001047)
0.1 0.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.3 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 2.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 4.5 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.0 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 3.0 GO:0019902 phosphatase binding(GO:0019902)
0.1 0.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 4.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 5.0 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 2.5 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 1.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.3 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.3 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 6.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 2.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.9 GO:0005521 lamin binding(GO:0005521)
0.1 2.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 20.6 GO:0045296 cadherin binding(GO:0045296)
0.1 2.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.2 GO:0035276 ethanol binding(GO:0035276)
0.1 5.2 GO:0042393 histone binding(GO:0042393)
0.1 1.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.8 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 3.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 43.9 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 7.8 GO:0051020 GTPase binding(GO:0051020)
0.0 1.2 GO:0032934 sterol binding(GO:0032934)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 1.1 GO:0030695 GTPase activator activity(GO:0005096) GTPase regulator activity(GO:0030695)
0.0 0.6 GO:0072509 calcium channel activity(GO:0005262) calcium ion transmembrane transporter activity(GO:0015085) divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846) complement component C3b binding(GO:0001851)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 79.2 PID BARD1 PATHWAY BARD1 signaling events
0.9 20.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.8 18.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.7 32.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.7 19.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.6 34.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.6 33.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.6 20.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.6 23.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.5 1.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5 30.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.4 24.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.4 10.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.4 24.3 PID TNF PATHWAY TNF receptor signaling pathway
0.4 41.0 PID E2F PATHWAY E2F transcription factor network
0.4 18.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.4 7.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.4 16.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 10.9 PID AURORA A PATHWAY Aurora A signaling
0.3 7.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.3 5.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 10.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 12.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 8.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.3 16.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 8.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.3 15.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 8.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 5.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 18.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 7.1 PID REELIN PATHWAY Reelin signaling pathway
0.3 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 7.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 6.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 8.0 PID ALK1 PATHWAY ALK1 signaling events
0.2 6.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 21.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 9.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 8.9 PID AURORA B PATHWAY Aurora B signaling
0.2 15.1 PID CMYB PATHWAY C-MYB transcription factor network
0.2 4.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 7.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 4.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 5.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 6.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 4.0 PID ATM PATHWAY ATM pathway
0.2 2.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 7.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 6.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 6.1 PID AP1 PATHWAY AP-1 transcription factor network
0.1 4.4 PID BMP PATHWAY BMP receptor signaling
0.1 3.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.3 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 1.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 2.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 5.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 50.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.9 26.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.8 18.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.8 65.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.6 24.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.5 13.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.3 20.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
1.3 9.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
1.3 23.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.1 39.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.0 12.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.0 4.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.9 8.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.8 8.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.8 13.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.8 20.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.7 22.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.7 24.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.7 11.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.7 30.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.7 11.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.7 10.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.7 6.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.7 6.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.6 7.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.6 16.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.6 3.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.6 18.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.6 56.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.6 32.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.6 4.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5 4.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.5 19.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.5 8.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.5 12.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 6.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 12.3 REACTOME KINESINS Genes involved in Kinesins
0.5 11.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.5 5.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.4 8.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.4 7.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.4 3.5 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.4 5.6 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.4 6.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.4 15.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.4 8.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 1.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.4 7.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.3 7.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 4.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.3 5.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 8.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.3 25.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 5.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 10.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 9.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.3 3.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 6.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 3.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 31.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.3 9.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 4.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 11.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.3 22.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 2.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 15.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.3 20.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 44.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.3 39.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 4.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 3.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 6.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 3.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 2.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 11.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 4.5 REACTOME TRANSLATION Genes involved in Translation
0.2 3.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 11.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 5.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 9.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 1.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 9.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 1.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.4 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 3.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 5.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 6.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 2.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 4.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.3 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 3.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 0.3 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 4.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.1 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.5 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.3 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.9 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis