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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for HOXB4_LHX9
Z-value: 0.92
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Transcription factors associated with HOXB4_LHX9
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXB4
|
ENSG00000182742.5 | homeobox B4 |
|
LHX9
|
ENSG00000143355.11 | LIM homeobox 9 |
Activity profile of HOXB4_LHX9 motif
Sorted Z-values of HOXB4_LHX9 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_169418195 | 25.35 |
ENST00000261509.6
ENST00000335742.7 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr15_-_72523924 | 19.05 |
ENST00000566809.1
ENST00000567087.1 ENST00000569050.1 ENST00000568883.1 |
PKM
|
pyruvate kinase, muscle |
| chr3_-_149095652 | 18.56 |
ENST00000305366.3
|
TM4SF1
|
transmembrane 4 L six family member 1 |
| chr7_-_87856280 | 17.53 |
ENST00000490437.1
ENST00000431660.1 |
SRI
|
sorcin |
| chr7_-_87856303 | 17.32 |
ENST00000394641.3
|
SRI
|
sorcin |
| chr6_-_38670897 | 15.09 |
ENST00000373365.4
|
GLO1
|
glyoxalase I |
| chr7_+_141438118 | 13.84 |
ENST00000265304.6
ENST00000498107.1 ENST00000467681.1 ENST00000465582.1 ENST00000463093.1 |
SSBP1
|
single-stranded DNA binding protein 1, mitochondrial |
| chr4_-_103749179 | 13.38 |
ENST00000502690.1
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chrX_-_77225135 | 13.12 |
ENST00000458128.1
|
PGAM4
|
phosphoglycerate mutase family member 4 |
| chr11_-_107729887 | 13.03 |
ENST00000525815.1
|
SLC35F2
|
solute carrier family 35, member F2 |
| chr3_+_138340049 | 11.96 |
ENST00000464668.1
|
FAIM
|
Fas apoptotic inhibitory molecule |
| chr4_-_103749205 | 11.15 |
ENST00000508249.1
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr17_+_66511540 | 10.65 |
ENST00000588188.2
|
PRKAR1A
|
protein kinase, cAMP-dependent, regulatory, type I, alpha |
| chr1_-_197115818 | 10.31 |
ENST00000367409.4
ENST00000294732.7 |
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| chr2_+_187454749 | 10.14 |
ENST00000261023.3
ENST00000374907.3 |
ITGAV
|
integrin, alpha V |
| chr3_-_185538849 | 9.44 |
ENST00000421047.2
|
IGF2BP2
|
insulin-like growth factor 2 mRNA binding protein 2 |
| chr3_+_138340067 | 8.87 |
ENST00000479848.1
|
FAIM
|
Fas apoptotic inhibitory molecule |
| chr6_+_114178512 | 8.59 |
ENST00000368635.4
|
MARCKS
|
myristoylated alanine-rich protein kinase C substrate |
| chr1_-_212965104 | 8.26 |
ENST00000422588.2
ENST00000366975.6 ENST00000366977.3 ENST00000366976.1 |
NSL1
|
NSL1, MIS12 kinetochore complex component |
| chr4_+_113568207 | 8.11 |
ENST00000511529.1
|
LARP7
|
La ribonucleoprotein domain family, member 7 |
| chr3_+_139063372 | 7.98 |
ENST00000478464.1
|
MRPS22
|
mitochondrial ribosomal protein S22 |
| chr2_+_102456277 | 7.62 |
ENST00000421882.1
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4 |
| chr3_+_23851928 | 7.56 |
ENST00000467766.1
ENST00000424381.1 |
UBE2E1
|
ubiquitin-conjugating enzyme E2E 1 |
| chr16_+_15489603 | 7.42 |
ENST00000568766.1
ENST00000287594.7 |
RP11-1021N1.1
MPV17L
|
Uncharacterized protein MPV17 mitochondrial membrane protein-like |
| chr7_-_107642348 | 7.33 |
ENST00000393561.1
|
LAMB1
|
laminin, beta 1 |
| chr12_+_64798095 | 7.29 |
ENST00000332707.5
|
XPOT
|
exportin, tRNA |
| chr17_+_48823975 | 7.25 |
ENST00000513969.1
ENST00000503728.1 |
LUC7L3
|
LUC7-like 3 (S. cerevisiae) |
| chr17_+_48823896 | 7.19 |
ENST00000511974.1
|
LUC7L3
|
LUC7-like 3 (S. cerevisiae) |
| chr5_-_176889381 | 7.18 |
ENST00000393563.4
ENST00000512501.1 |
DBN1
|
drebrin 1 |
| chrX_+_100663243 | 7.17 |
ENST00000316594.5
|
HNRNPH2
|
heterogeneous nuclear ribonucleoprotein H2 (H') |
| chr19_-_14945933 | 6.98 |
ENST00000322301.3
|
OR7A5
|
olfactory receptor, family 7, subfamily A, member 5 |
| chrX_-_100662881 | 6.98 |
ENST00000218516.3
|
GLA
|
galactosidase, alpha |
| chr11_-_63376013 | 6.83 |
ENST00000540943.1
|
PLA2G16
|
phospholipase A2, group XVI |
| chr6_+_34204642 | 6.72 |
ENST00000347617.6
ENST00000401473.3 ENST00000311487.5 ENST00000447654.1 ENST00000395004.3 |
HMGA1
|
high mobility group AT-hook 1 |
| chr14_-_67878917 | 6.58 |
ENST00000216446.4
|
PLEK2
|
pleckstrin 2 |
| chr12_-_8803128 | 6.58 |
ENST00000543467.1
|
MFAP5
|
microfibrillar associated protein 5 |
| chr2_-_176046391 | 6.53 |
ENST00000392541.3
ENST00000409194.1 |
ATP5G3
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) |
| chr10_-_58120996 | 6.50 |
ENST00000361148.6
ENST00000395405.1 ENST00000373944.3 |
ZWINT
|
ZW10 interacting kinetochore protein |
| chr20_-_1447467 | 6.41 |
ENST00000353088.2
ENST00000350991.4 |
NSFL1C
|
NSFL1 (p97) cofactor (p47) |
| chr12_+_49621658 | 6.35 |
ENST00000541364.1
|
TUBA1C
|
tubulin, alpha 1c |
| chr11_-_104827425 | 6.32 |
ENST00000393150.3
|
CASP4
|
caspase 4, apoptosis-related cysteine peptidase |
| chr8_-_90996837 | 6.27 |
ENST00000519426.1
ENST00000265433.3 |
NBN
|
nibrin |
| chr3_-_141719195 | 6.18 |
ENST00000397991.4
|
TFDP2
|
transcription factor Dp-2 (E2F dimerization partner 2) |
| chr2_+_234637754 | 6.06 |
ENST00000482026.1
ENST00000609767.1 |
UGT1A3
UGT1A1
|
UDP glucuronosyltransferase 1 family, polypeptide A3 UDP glucuronosyltransferase 1 family, polypeptide A8 |
| chr15_+_64680003 | 6.03 |
ENST00000261884.3
|
TRIP4
|
thyroid hormone receptor interactor 4 |
| chr20_+_19867150 | 5.95 |
ENST00000255006.6
|
RIN2
|
Ras and Rab interactor 2 |
| chr20_-_1447547 | 5.95 |
ENST00000476071.1
|
NSFL1C
|
NSFL1 (p97) cofactor (p47) |
| chr2_+_27886330 | 5.91 |
ENST00000326019.6
|
SLC4A1AP
|
solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| chr2_+_172778952 | 5.88 |
ENST00000392584.1
ENST00000264108.4 |
HAT1
|
histone acetyltransferase 1 |
| chr13_-_24007815 | 5.60 |
ENST00000382298.3
|
SACS
|
spastic ataxia of Charlevoix-Saguenay (sacsin) |
| chr4_-_103749313 | 5.38 |
ENST00000394803.5
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr10_+_5135981 | 5.23 |
ENST00000380554.3
|
AKR1C3
|
aldo-keto reductase family 1, member C3 |
| chr3_-_141747950 | 5.05 |
ENST00000497579.1
|
TFDP2
|
transcription factor Dp-2 (E2F dimerization partner 2) |
| chr2_+_237994519 | 5.03 |
ENST00000392008.2
ENST00000409334.1 ENST00000409629.1 |
COPS8
|
COP9 signalosome subunit 8 |
| chr1_+_155278539 | 4.97 |
ENST00000447866.1
|
FDPS
|
farnesyl diphosphate synthase |
| chr7_+_115862858 | 4.95 |
ENST00000393481.2
|
TES
|
testis derived transcript (3 LIM domains) |
| chr6_+_30687978 | 4.93 |
ENST00000327892.8
ENST00000435534.1 |
TUBB
|
tubulin, beta class I |
| chr20_-_43133491 | 4.85 |
ENST00000411544.1
|
SERINC3
|
serine incorporator 3 |
| chr6_-_82957433 | 4.64 |
ENST00000306270.7
|
IBTK
|
inhibitor of Bruton agammaglobulinemia tyrosine kinase |
| chr18_-_51751132 | 4.63 |
ENST00000256429.3
|
MBD2
|
methyl-CpG binding domain protein 2 |
| chr8_-_90996459 | 4.62 |
ENST00000517337.1
ENST00000409330.1 |
NBN
|
nibrin |
| chr7_+_107224364 | 4.57 |
ENST00000491150.1
|
BCAP29
|
B-cell receptor-associated protein 29 |
| chr2_-_74619152 | 4.55 |
ENST00000440727.1
ENST00000409240.1 |
DCTN1
|
dynactin 1 |
| chr18_-_47018869 | 4.47 |
ENST00000583036.1
ENST00000580261.1 |
RPL17
|
ribosomal protein L17 |
| chr1_+_155278625 | 4.41 |
ENST00000368356.4
ENST00000356657.6 |
FDPS
|
farnesyl diphosphate synthase |
| chr4_-_103749105 | 4.38 |
ENST00000394801.4
ENST00000394804.2 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr8_+_104310661 | 4.38 |
ENST00000522566.1
|
FZD6
|
frizzled family receptor 6 |
| chrX_-_16887963 | 4.28 |
ENST00000380084.4
|
RBBP7
|
retinoblastoma binding protein 7 |
| chr15_-_55489097 | 4.22 |
ENST00000260443.4
|
RSL24D1
|
ribosomal L24 domain containing 1 |
| chr10_-_105845674 | 4.16 |
ENST00000353479.5
ENST00000369733.3 |
COL17A1
|
collagen, type XVII, alpha 1 |
| chr2_-_70520539 | 4.10 |
ENST00000482975.2
ENST00000438261.1 |
SNRPG
|
small nuclear ribonucleoprotein polypeptide G |
| chr12_-_10978957 | 4.08 |
ENST00000240619.2
|
TAS2R10
|
taste receptor, type 2, member 10 |
| chr17_-_39743139 | 3.99 |
ENST00000167586.6
|
KRT14
|
keratin 14 |
| chr18_-_47018897 | 3.97 |
ENST00000418495.1
|
RPL17
|
ribosomal protein L17 |
| chr11_+_35201826 | 3.96 |
ENST00000531873.1
|
CD44
|
CD44 molecule (Indian blood group) |
| chr2_-_136678123 | 3.96 |
ENST00000422708.1
|
DARS
|
aspartyl-tRNA synthetase |
| chr14_+_55595762 | 3.87 |
ENST00000254301.9
|
LGALS3
|
lectin, galactoside-binding, soluble, 3 |
| chr3_+_148709128 | 3.82 |
ENST00000345003.4
ENST00000296048.6 ENST00000483267.1 |
GYG1
|
glycogenin 1 |
| chr2_+_219110149 | 3.80 |
ENST00000456575.1
|
ARPC2
|
actin related protein 2/3 complex, subunit 2, 34kDa |
| chr2_-_74618964 | 3.72 |
ENST00000417090.1
ENST00000409868.1 |
DCTN1
|
dynactin 1 |
| chr1_-_89357179 | 3.71 |
ENST00000448623.1
ENST00000418217.1 ENST00000370500.5 |
GTF2B
|
general transcription factor IIB |
| chr7_-_144435985 | 3.70 |
ENST00000549981.1
|
TPK1
|
thiamin pyrophosphokinase 1 |
| chr3_+_136649311 | 3.69 |
ENST00000469404.1
ENST00000467911.1 |
NCK1
|
NCK adaptor protein 1 |
| chr13_-_31038370 | 3.65 |
ENST00000399489.1
ENST00000339872.4 |
HMGB1
|
high mobility group box 1 |
| chr4_-_103748880 | 3.59 |
ENST00000453744.2
ENST00000349311.8 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr3_+_157154578 | 3.42 |
ENST00000295927.3
|
PTX3
|
pentraxin 3, long |
| chr17_+_33914460 | 3.40 |
ENST00000537622.2
|
AP2B1
|
adaptor-related protein complex 2, beta 1 subunit |
| chr3_-_149293990 | 3.38 |
ENST00000472417.1
|
WWTR1
|
WW domain containing transcription regulator 1 |
| chr18_-_47018769 | 3.38 |
ENST00000583637.1
ENST00000578528.1 ENST00000578532.1 ENST00000580387.1 ENST00000579248.1 ENST00000581373.1 |
RPL17
|
ribosomal protein L17 |
| chr8_-_49834299 | 3.32 |
ENST00000396822.1
|
SNAI2
|
snail family zinc finger 2 |
| chr20_-_33735070 | 3.30 |
ENST00000374491.3
ENST00000542871.1 ENST00000374492.3 |
EDEM2
|
ER degradation enhancer, mannosidase alpha-like 2 |
| chr7_+_73868120 | 3.28 |
ENST00000265755.3
|
GTF2IRD1
|
GTF2I repeat domain containing 1 |
| chr14_-_104387888 | 3.27 |
ENST00000286953.3
|
C14orf2
|
chromosome 14 open reading frame 2 |
| chr4_+_169418255 | 3.26 |
ENST00000505667.1
ENST00000511948.1 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr15_+_66679155 | 3.21 |
ENST00000307102.5
|
MAP2K1
|
mitogen-activated protein kinase kinase 1 |
| chr7_+_116654935 | 3.17 |
ENST00000432298.1
ENST00000422922.1 |
ST7
|
suppression of tumorigenicity 7 |
| chr9_+_125132803 | 3.17 |
ENST00000540753.1
|
PTGS1
|
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| chr11_-_18548426 | 3.08 |
ENST00000357193.3
ENST00000536719.1 |
TSG101
|
tumor susceptibility 101 |
| chr10_+_122610687 | 3.06 |
ENST00000263461.6
|
WDR11
|
WD repeat domain 11 |
| chr1_+_81771806 | 3.04 |
ENST00000370721.1
ENST00000370727.1 ENST00000370725.1 ENST00000370723.1 ENST00000370728.1 ENST00000370730.1 |
LPHN2
|
latrophilin 2 |
| chr14_-_104387831 | 3.03 |
ENST00000557040.1
ENST00000414262.2 ENST00000555030.1 ENST00000554713.1 ENST00000553430.1 |
C14orf2
|
chromosome 14 open reading frame 2 |
| chr14_+_35591928 | 3.03 |
ENST00000605870.1
ENST00000557404.3 |
KIAA0391
|
KIAA0391 |
| chr11_+_57480046 | 3.01 |
ENST00000378312.4
ENST00000278422.4 |
TMX2
|
thioredoxin-related transmembrane protein 2 |
| chr7_+_73868220 | 2.99 |
ENST00000455841.2
|
GTF2IRD1
|
GTF2I repeat domain containing 1 |
| chr7_+_23145884 | 2.95 |
ENST00000409689.1
ENST00000410047.1 |
KLHL7
|
kelch-like family member 7 |
| chr12_+_112279782 | 2.91 |
ENST00000550735.2
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5 |
| chr6_+_36562132 | 2.90 |
ENST00000373715.6
ENST00000339436.7 |
SRSF3
|
serine/arginine-rich splicing factor 3 |
| chr1_-_67266939 | 2.88 |
ENST00000304526.2
|
INSL5
|
insulin-like 5 |
| chr12_+_20963632 | 2.85 |
ENST00000540853.1
ENST00000261196.2 |
SLCO1B3
|
solute carrier organic anion transporter family, member 1B3 |
| chr15_+_80351910 | 2.85 |
ENST00000261749.6
ENST00000561060.1 |
ZFAND6
|
zinc finger, AN1-type domain 6 |
| chr2_-_191115229 | 2.76 |
ENST00000409820.2
ENST00000410045.1 |
HIBCH
|
3-hydroxyisobutyryl-CoA hydrolase |
| chr16_-_66764119 | 2.70 |
ENST00000569320.1
|
DYNC1LI2
|
dynein, cytoplasmic 1, light intermediate chain 2 |
| chr13_+_48611665 | 2.67 |
ENST00000258662.2
|
NUDT15
|
nudix (nucleoside diphosphate linked moiety X)-type motif 15 |
| chr8_-_49833978 | 2.59 |
ENST00000020945.1
|
SNAI2
|
snail family zinc finger 2 |
| chr6_+_30585486 | 2.55 |
ENST00000259873.4
ENST00000506373.2 |
MRPS18B
|
mitochondrial ribosomal protein S18B |
| chr5_+_36152091 | 2.49 |
ENST00000274254.5
|
SKP2
|
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| chr22_+_22730353 | 2.48 |
ENST00000390296.2
|
IGLV5-45
|
immunoglobulin lambda variable 5-45 |
| chr3_+_44840679 | 2.44 |
ENST00000425755.1
|
KIF15
|
kinesin family member 15 |
| chr6_-_109702885 | 2.42 |
ENST00000504373.1
|
CD164
|
CD164 molecule, sialomucin |
| chr18_+_21452804 | 2.32 |
ENST00000269217.6
|
LAMA3
|
laminin, alpha 3 |
| chr1_-_77685084 | 2.31 |
ENST00000370812.3
ENST00000359130.1 ENST00000445065.1 ENST00000370813.5 |
PIGK
|
phosphatidylinositol glycan anchor biosynthesis, class K |
| chr15_+_67418047 | 2.27 |
ENST00000540846.2
|
SMAD3
|
SMAD family member 3 |
| chr7_+_73868439 | 2.25 |
ENST00000424337.2
|
GTF2IRD1
|
GTF2I repeat domain containing 1 |
| chr1_-_153518270 | 2.25 |
ENST00000354332.4
ENST00000368716.4 |
S100A4
|
S100 calcium binding protein A4 |
| chr12_+_20963647 | 2.24 |
ENST00000381545.3
|
SLCO1B3
|
solute carrier organic anion transporter family, member 1B3 |
| chr7_-_22862406 | 2.21 |
ENST00000372879.4
|
TOMM7
|
translocase of outer mitochondrial membrane 7 homolog (yeast) |
| chr2_-_27886460 | 2.21 |
ENST00000404798.2
ENST00000405491.1 ENST00000464789.2 ENST00000406540.1 |
SUPT7L
|
suppressor of Ty 7 (S. cerevisiae)-like |
| chr2_-_88285309 | 2.18 |
ENST00000420840.2
|
RGPD2
|
RANBP2-like and GRIP domain containing 2 |
| chr6_+_42584847 | 2.18 |
ENST00000372883.3
|
UBR2
|
ubiquitin protein ligase E3 component n-recognin 2 |
| chr5_+_36152163 | 2.16 |
ENST00000274255.6
|
SKP2
|
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| chr17_+_33914276 | 2.14 |
ENST00000592545.1
ENST00000538556.1 ENST00000312678.8 ENST00000589344.1 |
AP2B1
|
adaptor-related protein complex 2, beta 1 subunit |
| chr19_+_23945768 | 2.11 |
ENST00000486528.1
ENST00000496398.1 |
RPSAP58
|
ribosomal protein SA pseudogene 58 |
| chr14_+_35591735 | 2.09 |
ENST00000604948.1
ENST00000605201.1 ENST00000250377.7 ENST00000321130.10 ENST00000534898.4 |
KIAA0391
|
KIAA0391 |
| chrX_+_108779004 | 2.05 |
ENST00000218004.1
|
NXT2
|
nuclear transport factor 2-like export factor 2 |
| chr15_+_89631381 | 2.03 |
ENST00000352732.5
|
ABHD2
|
abhydrolase domain containing 2 |
| chr7_-_86849883 | 2.00 |
ENST00000433078.1
|
TMEM243
|
transmembrane protein 243, mitochondrial |
| chr1_-_39339777 | 1.97 |
ENST00000397572.2
|
MYCBP
|
MYC binding protein |
| chr4_-_39979576 | 1.94 |
ENST00000303538.8
ENST00000503396.1 |
PDS5A
|
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) |
| chr4_+_169552748 | 1.92 |
ENST00000504519.1
ENST00000512127.1 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr3_-_151034734 | 1.92 |
ENST00000260843.4
|
GPR87
|
G protein-coupled receptor 87 |
| chrX_-_100872911 | 1.92 |
ENST00000361910.4
ENST00000539247.1 ENST00000538627.1 |
ARMCX6
|
armadillo repeat containing, X-linked 6 |
| chr14_-_35591433 | 1.80 |
ENST00000261475.5
ENST00000555644.1 |
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma |
| chr14_+_50234309 | 1.71 |
ENST00000298307.5
|
KLHDC2
|
kelch domain containing 2 |
| chr9_-_128246769 | 1.71 |
ENST00000444226.1
|
MAPKAP1
|
mitogen-activated protein kinase associated protein 1 |
| chr1_-_190446759 | 1.71 |
ENST00000367462.3
|
BRINP3
|
bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| chr8_-_30670384 | 1.59 |
ENST00000221138.4
ENST00000518243.1 |
PPP2CB
|
protein phosphatase 2, catalytic subunit, beta isozyme |
| chr18_+_21452964 | 1.55 |
ENST00000587184.1
|
LAMA3
|
laminin, alpha 3 |
| chr5_-_16916624 | 1.52 |
ENST00000513882.1
|
MYO10
|
myosin X |
| chr16_+_24549014 | 1.52 |
ENST00000564314.1
ENST00000567686.1 |
RBBP6
|
retinoblastoma binding protein 6 |
| chr22_-_32651326 | 1.52 |
ENST00000266086.4
|
SLC5A4
|
solute carrier family 5 (glucose activated ion channel), member 4 |
| chr5_-_125930929 | 1.50 |
ENST00000553117.1
ENST00000447989.2 ENST00000409134.3 |
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1 |
| chr8_+_9953214 | 1.47 |
ENST00000382490.5
|
MSRA
|
methionine sulfoxide reductase A |
| chrX_+_70503433 | 1.39 |
ENST00000276079.8
ENST00000373856.3 ENST00000373841.1 ENST00000420903.1 |
NONO
|
non-POU domain containing, octamer-binding |
| chr8_+_9953061 | 1.38 |
ENST00000522907.1
ENST00000528246.1 |
MSRA
|
methionine sulfoxide reductase A |
| chr18_-_3219847 | 1.33 |
ENST00000261606.7
|
MYOM1
|
myomesin 1 |
| chr14_+_35591858 | 1.31 |
ENST00000603544.1
|
KIAA0391
|
KIAA0391 |
| chr22_-_39268308 | 1.26 |
ENST00000407418.3
|
CBX6
|
chromobox homolog 6 |
| chr10_+_101491968 | 1.22 |
ENST00000370476.5
ENST00000370472.4 |
CUTC
|
cutC copper transporter |
| chr14_+_23938891 | 1.12 |
ENST00000408901.3
ENST00000397154.3 ENST00000555128.1 |
NGDN
|
neuroguidin, EIF4E binding protein |
| chr2_+_87135076 | 1.11 |
ENST00000409776.2
|
RGPD1
|
RANBP2-like and GRIP domain containing 1 |
| chr20_+_30697298 | 1.11 |
ENST00000398022.2
|
TM9SF4
|
transmembrane 9 superfamily protein member 4 |
| chr5_+_89770664 | 1.05 |
ENST00000503973.1
ENST00000399107.1 |
POLR3G
|
polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| chr5_+_179159813 | 1.05 |
ENST00000292599.3
|
MAML1
|
mastermind-like 1 (Drosophila) |
| chr5_+_89770696 | 1.05 |
ENST00000504930.1
ENST00000514483.1 |
POLR3G
|
polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| chr15_-_60771280 | 0.95 |
ENST00000560072.1
ENST00000560406.1 ENST00000560520.1 ENST00000261520.4 ENST00000439632.1 |
NARG2
|
NMDA receptor regulated 2 |
| chr6_+_29079668 | 0.93 |
ENST00000377169.1
|
OR2J3
|
olfactory receptor, family 2, subfamily J, member 3 |
| chr1_+_201979645 | 0.93 |
ENST00000367284.5
ENST00000367283.3 |
ELF3
|
E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| chr1_-_109584608 | 0.92 |
ENST00000400794.3
ENST00000528747.1 ENST00000369962.3 ENST00000361054.3 |
WDR47
|
WD repeat domain 47 |
| chr11_-_327537 | 0.87 |
ENST00000602735.1
|
IFITM3
|
interferon induced transmembrane protein 3 |
| chrX_-_18690210 | 0.86 |
ENST00000379984.3
|
RS1
|
retinoschisin 1 |
| chr17_+_40118759 | 0.85 |
ENST00000393892.3
|
CNP
|
2',3'-cyclic nucleotide 3' phosphodiesterase |
| chr3_-_122233723 | 0.85 |
ENST00000493510.1
ENST00000344337.6 ENST00000476916.1 ENST00000465882.1 |
KPNA1
|
karyopherin alpha 1 (importin alpha 5) |
| chr1_+_62439037 | 0.79 |
ENST00000545929.1
|
INADL
|
InaD-like (Drosophila) |
| chr4_-_70518941 | 0.77 |
ENST00000286604.4
ENST00000505512.1 ENST00000514019.1 |
UGT2A1
UGT2A1
|
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus |
| chr5_+_140593509 | 0.74 |
ENST00000341948.4
|
PCDHB13
|
protocadherin beta 13 |
| chr6_+_26365443 | 0.68 |
ENST00000527422.1
ENST00000356386.2 ENST00000396934.3 ENST00000377708.2 ENST00000396948.1 ENST00000508906.2 |
BTN3A2
|
butyrophilin, subfamily 3, member A2 |
| chrX_+_19362011 | 0.67 |
ENST00000379806.5
ENST00000545074.1 ENST00000540249.1 ENST00000423505.1 ENST00000417819.1 ENST00000422285.2 ENST00000355808.5 ENST00000379805.3 |
PDHA1
|
pyruvate dehydrogenase (lipoamide) alpha 1 |
| chrX_+_84258832 | 0.66 |
ENST00000373173.2
|
APOOL
|
apolipoprotein O-like |
| chr17_-_37607497 | 0.65 |
ENST00000394287.3
ENST00000300651.6 |
MED1
|
mediator complex subunit 1 |
| chrX_+_100075368 | 0.64 |
ENST00000415585.2
ENST00000372972.2 ENST00000413437.1 |
CSTF2
|
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa |
| chr4_+_69962185 | 0.62 |
ENST00000305231.7
|
UGT2B7
|
UDP glucuronosyltransferase 2 family, polypeptide B7 |
| chr11_+_22696314 | 0.62 |
ENST00000532398.1
ENST00000433790.1 |
GAS2
|
growth arrest-specific 2 |
| chr5_+_112849373 | 0.62 |
ENST00000161863.4
ENST00000515883.1 |
YTHDC2
|
YTH domain containing 2 |
| chr14_+_104182105 | 0.60 |
ENST00000311141.2
|
ZFYVE21
|
zinc finger, FYVE domain containing 21 |
| chr4_+_69962212 | 0.60 |
ENST00000508661.1
|
UGT2B7
|
UDP glucuronosyltransferase 2 family, polypeptide B7 |
| chr14_+_104182061 | 0.59 |
ENST00000216602.6
|
ZFYVE21
|
zinc finger, FYVE domain containing 21 |
| chr3_+_186353756 | 0.57 |
ENST00000431018.1
ENST00000450521.1 ENST00000539949.1 |
FETUB
|
fetuin B |
| chr3_-_164796269 | 0.57 |
ENST00000264382.3
|
SI
|
sucrase-isomaltase (alpha-glucosidase) |
| chr17_+_67498538 | 0.54 |
ENST00000589647.1
|
MAP2K6
|
mitogen-activated protein kinase kinase 6 |
| chr2_-_225811747 | 0.52 |
ENST00000409592.3
|
DOCK10
|
dedicator of cytokinesis 10 |
| chr18_-_24443151 | 0.51 |
ENST00000440832.3
|
AQP4
|
aquaporin 4 |
| chr5_-_149829314 | 0.51 |
ENST00000407193.1
|
RPS14
|
ribosomal protein S14 |
| chr8_+_105235572 | 0.51 |
ENST00000523362.1
|
RIMS2
|
regulating synaptic membrane exocytosis 2 |
| chr2_+_102953608 | 0.47 |
ENST00000311734.2
ENST00000409584.1 |
IL1RL1
|
interleukin 1 receptor-like 1 |
| chr20_-_21494654 | 0.46 |
ENST00000377142.4
|
NKX2-2
|
NK2 homeobox 2 |
| chr12_-_68619586 | 0.46 |
ENST00000229134.4
|
IL26
|
interleukin 26 |
| chr2_+_27255806 | 0.45 |
ENST00000238788.9
ENST00000404032.3 |
TMEM214
|
transmembrane protein 214 |
| chr12_-_10605929 | 0.45 |
ENST00000347831.5
ENST00000359151.3 |
KLRC1
|
killer cell lectin-like receptor subfamily C, member 1 |
| chr14_-_80697396 | 0.44 |
ENST00000557010.1
|
DIO2
|
deiodinase, iodothyronine, type II |
| chr4_-_90757364 | 0.43 |
ENST00000508895.1
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor) |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB4_LHX9
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 34.8 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 3.3 | 13.1 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 3.2 | 19.1 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 2.7 | 10.9 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 2.5 | 10.1 | GO:0045715 | negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) |
| 2.2 | 15.1 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
| 2.0 | 5.9 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 1.9 | 9.4 | GO:0033383 | geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337) |
| 1.9 | 7.4 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 1.8 | 7.3 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 1.7 | 5.2 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 1.7 | 10.3 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 1.7 | 8.5 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 1.7 | 6.7 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 1.4 | 4.3 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 1.4 | 13.8 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 1.3 | 30.5 | GO:0003334 | keratinocyte development(GO:0003334) |
| 1.3 | 4.0 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 1.3 | 3.9 | GO:2000521 | negative regulation of immunological synapse formation(GO:2000521) |
| 1.2 | 3.7 | GO:1903676 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 1.2 | 6.1 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 1.2 | 7.2 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 1.1 | 5.5 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 1.1 | 3.3 | GO:0036511 | trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) |
| 1.1 | 4.4 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 1.1 | 6.4 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 1.1 | 4.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 1.0 | 8.3 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 1.0 | 3.1 | GO:2000397 | ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 1.0 | 6.8 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.9 | 7.6 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.9 | 3.7 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.9 | 3.6 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.9 | 7.0 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.8 | 4.1 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.8 | 36.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.8 | 10.7 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.7 | 5.9 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.7 | 6.3 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.7 | 4.9 | GO:0009597 | detection of virus(GO:0009597) |
| 0.7 | 3.4 | GO:0052199 | negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199) |
| 0.7 | 2.7 | GO:0006203 | dGTP catabolic process(GO:0006203) |
| 0.7 | 4.0 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 0.6 | 3.7 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 0.6 | 2.9 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.6 | 4.0 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.5 | 3.2 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 0.5 | 4.6 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.5 | 2.3 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.4 | 2.2 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.4 | 3.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.4 | 8.6 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.4 | 5.6 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.4 | 12.4 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.4 | 14.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.4 | 1.1 | GO:0060920 | atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926) |
| 0.3 | 1.4 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.3 | 2.3 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.3 | 2.8 | GO:0030091 | protein repair(GO:0030091) |
| 0.3 | 5.0 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.3 | 6.8 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.3 | 8.0 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 1.7 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.3 | 2.9 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.2 | 1.8 | GO:0002759 | regulation of antimicrobial humoral response(GO:0002759) |
| 0.2 | 0.6 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.2 | 1.5 | GO:0042426 | choline catabolic process(GO:0042426) |
| 0.2 | 11.2 | GO:1900739 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.2 | 6.5 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.2 | 2.2 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.2 | 3.3 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.2 | 1.1 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.2 | 0.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.2 | 1.3 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 0.2 | 4.6 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.2 | 6.6 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.2 | 0.5 | GO:0021779 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.2 | 4.1 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.1 | 7.3 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.1 | 10.5 | GO:0070126 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.1 | 3.0 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.1 | 4.1 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.1 | 3.3 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 6.0 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 5.1 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 3.8 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.1 | 0.6 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.1 | 0.4 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 0.1 | 1.9 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.1 | 11.1 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.1 | 1.7 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.1 | 12.5 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.1 | 0.9 | GO:0009642 | response to light intensity(GO:0009642) |
| 0.1 | 0.4 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470) |
| 0.1 | 0.9 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.1 | 12.7 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.1 | 0.6 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 0.5 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.1 | 12.8 | GO:0030705 | cytoskeleton-dependent intracellular transport(GO:0030705) |
| 0.1 | 0.7 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.1 | 0.7 | GO:0042407 | cristae formation(GO:0042407) |
| 0.1 | 0.3 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.1 | 2.1 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 0.6 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 2.9 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 0.5 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 0.3 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 1.5 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.1 | 1.0 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.0 | 0.4 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 1.1 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.5 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.0 | 2.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 1.2 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.0 | 0.8 | GO:0019054 | modulation by virus of host process(GO:0019054) |
| 0.0 | 0.3 | GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation(GO:0021940) |
| 0.0 | 0.9 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.0 | 0.4 | GO:0042492 | gamma-delta T cell differentiation(GO:0042492) |
| 0.0 | 2.2 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 4.0 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.0 | 1.8 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 0.0 | 0.8 | GO:0046902 | regulation of mitochondrial membrane permeability(GO:0046902) |
| 0.0 | 0.2 | GO:0015816 | glycine transport(GO:0015816) |
| 0.0 | 0.7 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.4 | GO:0002566 | somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.0 | 0.5 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 2.1 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.0 | 6.7 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.0 | 0.5 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.6 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 0.3 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
| 0.0 | 1.5 | GO:0006275 | regulation of DNA replication(GO:0006275) |
| 0.0 | 0.0 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183) |
| 0.0 | 0.2 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.0 | 0.3 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.0 | 10.1 | GO:0043066 | negative regulation of apoptotic process(GO:0043066) |
| 0.0 | 0.5 | GO:1904894 | positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 34.8 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 3.4 | 10.1 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 3.1 | 12.4 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 2.4 | 7.3 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 1.7 | 8.3 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 1.6 | 10.9 | GO:0030870 | Mre11 complex(GO:0030870) |
| 1.5 | 10.3 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 1.3 | 6.4 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 1.3 | 3.8 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 1.1 | 6.3 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 0.8 | 2.4 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
| 0.8 | 18.5 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.8 | 2.3 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.6 | 6.7 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.6 | 30.5 | GO:0002102 | podosome(GO:0002102) |
| 0.6 | 4.0 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.6 | 8.3 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.5 | 10.7 | GO:0031588 | cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588) |
| 0.5 | 13.1 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.5 | 3.9 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.4 | 3.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.4 | 10.5 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.4 | 6.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.3 | 3.7 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.3 | 1.3 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.3 | 4.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.3 | 6.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.3 | 2.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.3 | 6.6 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 5.6 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.3 | 2.3 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.3 | 1.9 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.3 | 4.1 | GO:0043073 | germ cell nucleus(GO:0043073) |
| 0.3 | 13.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.2 | 7.2 | GO:0005921 | gap junction(GO:0005921) |
| 0.2 | 3.7 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.2 | 1.1 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.2 | 6.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.2 | 4.0 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.2 | 4.2 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.2 | 1.4 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.2 | 14.2 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.2 | 4.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 4.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 16.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 26.5 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.1 | 1.7 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 2.7 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 5.0 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 4.0 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 0.7 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.1 | 2.7 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 0.8 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 2.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 7.0 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 3.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 1.5 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.1 | 6.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 3.4 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 4.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 9.4 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 0.7 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 6.4 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 0.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.5 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.1 | 26.6 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.1 | 0.3 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.0 | 1.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 7.7 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 8.3 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 1.3 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 1.1 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 3.2 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.9 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 0.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.4 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 5.9 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 3.4 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.9 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.8 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.0 | 0.8 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.0 | 0.5 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.8 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 7.1 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.8 | 19.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 3.3 | 13.1 | GO:0004082 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 2.0 | 10.1 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 1.9 | 15.1 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 1.9 | 9.4 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 1.7 | 7.0 | GO:0016936 | galactoside binding(GO:0016936) |
| 1.4 | 6.8 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 1.3 | 5.2 | GO:0047718 | enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718) |
| 1.3 | 29.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 1.3 | 7.6 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 1.2 | 4.6 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 1.0 | 3.8 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 1.0 | 7.6 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.9 | 34.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.9 | 2.7 | GO:0008413 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
| 0.9 | 37.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.8 | 3.3 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.8 | 4.0 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.8 | 2.3 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.7 | 3.7 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.7 | 4.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.6 | 3.6 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.6 | 6.5 | GO:0046790 | virion binding(GO:0046790) |
| 0.6 | 2.8 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.5 | 10.7 | GO:0008603 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.5 | 7.4 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.5 | 3.9 | GO:0019863 | IgE binding(GO:0019863) |
| 0.5 | 3.7 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.5 | 2.3 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.5 | 6.3 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.4 | 2.0 | GO:0070728 | leucine binding(GO:0070728) |
| 0.4 | 4.8 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.4 | 6.4 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.4 | 7.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.4 | 1.5 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.4 | 4.1 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.4 | 9.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.3 | 4.9 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.3 | 10.3 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.3 | 5.5 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.3 | 8.7 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.3 | 5.9 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.2 | 2.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 6.7 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.2 | 7.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.2 | 2.2 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.2 | 1.2 | GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) |
| 0.2 | 0.6 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.2 | 7.9 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.2 | 3.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.2 | 1.9 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.2 | 1.5 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.2 | 8.6 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.2 | 0.7 | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.2 | 7.3 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.2 | 4.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.2 | 0.5 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 0.2 | 2.8 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
| 0.1 | 3.1 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.1 | 3.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 2.2 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.1 | 14.9 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.1 | 2.7 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 26.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 3.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 6.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 9.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 3.7 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 4.3 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 0.4 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.1 | 10.3 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 18.9 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.1 | 0.4 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 10.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 0.4 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.1 | 1.5 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 0.6 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 2.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 1.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 2.1 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.0 | 6.5 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 1.4 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 0.5 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.0 | 5.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.5 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 2.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 7.4 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 0.3 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 10.1 | GO:0008134 | transcription factor binding(GO:0008134) |
| 0.0 | 0.4 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 1.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 1.3 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 4.6 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.8 | GO:0004112 | cyclic-nucleotide phosphodiesterase activity(GO:0004112) |
| 0.0 | 0.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.2 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.5 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 48.8 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.4 | 8.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.3 | 10.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.2 | 14.5 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.2 | 8.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 10.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.2 | 13.7 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.2 | 4.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 11.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 4.0 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.1 | 3.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 7.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 6.0 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 3.1 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 4.2 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 3.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 5.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 2.6 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 8.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 3.6 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 4.8 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.1 | 1.5 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 2.9 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 5.2 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 4.0 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 1.1 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.5 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 1.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.4 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 37.9 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.8 | 8.6 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.7 | 6.7 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.5 | 10.1 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.5 | 3.1 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.4 | 10.9 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.4 | 6.8 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.3 | 10.7 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.3 | 3.2 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.3 | 8.1 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.3 | 9.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.3 | 4.1 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.3 | 5.5 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.2 | 7.5 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.2 | 6.0 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.2 | 3.3 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 6.3 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.2 | 5.1 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 4.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.2 | 7.3 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.2 | 1.6 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.2 | 3.7 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 12.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 7.0 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.1 | 12.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 3.8 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 3.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 2.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 3.7 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 4.0 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 1.1 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 3.5 | REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | Genes involved in Cleavage of Growing Transcript in the Termination Region |
| 0.1 | 4.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 12.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 2.3 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 4.1 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 2.3 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.1 | 7.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 4.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 6.5 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 2.9 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 1.7 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.1 | 3.7 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 0.6 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 8.9 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.0 | 0.7 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 2.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.5 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 2.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 1.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.8 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.0 | 0.9 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 2.2 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.4 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 2.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |