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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXC10_HOXD13

Z-value: 1.93

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Transcription factors associated with HOXC10_HOXD13

Gene Symbol Gene ID Gene Info
ENSG00000180818.4 homeobox C10
ENSG00000128714.5 homeobox D13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD13hg19_v2_chr2_+_176957619_1769576190.391.5e-09Click!
HOXC10hg19_v2_chr12_+_54378923_54378970-0.152.8e-02Click!

Activity profile of HOXC10_HOXD13 motif

Sorted Z-values of HOXC10_HOXD13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91539918 54.23 ENST00000548218.1
decorin
chr12_-_15038779 44.42 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr11_+_118401706 44.40 ENST00000411589.2
ENST00000442938.2
ENST00000359862.4
transmembrane protein 25
chr6_+_42847348 37.07 ENST00000493763.1
ENST00000304734.5
ribosomal protein L7-like 1
chr6_+_151042224 36.99 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr5_-_42825983 34.48 ENST00000506577.1
selenoprotein P, plasma, 1
chr1_+_90460661 34.02 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
zinc finger protein 326
chr12_-_91576561 33.21 ENST00000547568.2
ENST00000552962.1
decorin
chr18_-_52989217 30.03 ENST00000570287.2
transcription factor 4
chr12_-_91576429 29.78 ENST00000552145.1
ENST00000546745.1
decorin
chr2_-_216300784 28.51 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr12_-_91573132 28.50 ENST00000550563.1
ENST00000546370.1
decorin
chr3_-_48057890 26.29 ENST00000434267.1
microtubule-associated protein 4
chr12_-_91573249 25.56 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr12_-_91576750 25.07 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
decorin
chr2_-_136288113 23.70 ENST00000401392.1
zinc finger, RAN-binding domain containing 3
chr4_-_88450612 23.60 ENST00000418378.1
ENST00000282470.6
SPARC-like 1 (hevin)
chr3_-_112127981 22.80 ENST00000486726.2
RP11-231E6.1
chrX_+_73164149 21.38 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX transcript, XIST activator (non-protein coding)
chrX_-_103401649 19.38 ENST00000357421.4
solute carrier family 25, member 53
chr9_+_101705893 19.06 ENST00000375001.3
collagen, type XV, alpha 1
chr3_-_195310802 18.93 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr11_+_117070037 17.05 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
transgelin
chr8_+_94241867 16.29 ENST00000598428.1
Uncharacterized protein
chr2_-_238322800 16.23 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
collagen, type VI, alpha 3
chr9_+_139871948 16.20 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
prostaglandin D2 synthase 21kDa (brain)
chr19_-_10420459 15.89 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr22_+_39916558 15.88 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr3_-_123339418 15.85 ENST00000583087.1
myosin light chain kinase
chr18_-_74728998 15.74 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr2_-_86333244 15.69 ENST00000263857.6
ENST00000409681.1
polymerase (RNA) I polypeptide A, 194kDa
chr2_+_67624430 15.66 ENST00000272342.5
Ewing tumor-associated antigen 1
chr3_+_189507460 15.65 ENST00000434928.1
tumor protein p63
chr18_-_52989525 15.23 ENST00000457482.3
transcription factor 4
chr4_+_71248795 15.12 ENST00000304915.3
submaxillary gland androgen regulated protein 3B
chr3_-_123339343 15.02 ENST00000578202.1
myosin light chain kinase
chr5_-_43412418 14.44 ENST00000537013.1
ENST00000361115.4
chemokine (C-C motif) ligand 28
chrX_-_73072534 13.81 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr11_-_76155700 13.72 ENST00000572035.1
RP11-111M22.3
chr18_-_53069419 13.55 ENST00000570177.2
transcription factor 4
chr1_+_152957707 12.94 ENST00000368762.1
small proline-rich protein 1A
chr14_-_89878369 12.59 ENST00000553840.1
ENST00000556916.1
forkhead box N3
chr7_+_134464414 12.52 ENST00000361901.2
caldesmon 1
chr2_-_238323007 12.46 ENST00000295550.4
collagen, type VI, alpha 3
chr4_-_48018580 11.96 ENST00000514170.1
cyclic nucleotide gated channel alpha 1
chr13_-_46626847 11.93 ENST00000242848.4
ENST00000282007.3
zinc finger CCCH-type containing 13
chr12_-_52715179 11.81 ENST00000293670.3
keratin 83
chr9_+_105757590 11.71 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr17_+_38083977 11.60 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr11_-_76155618 11.59 ENST00000530759.1
RP11-111M22.3
chr17_-_46690839 11.56 ENST00000498634.2
homeobox B8
chr21_-_28217721 11.47 ENST00000284984.3
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr14_-_21493123 11.29 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr16_-_25122785 11.16 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
chr18_-_5396271 10.96 ENST00000579951.1
erythrocyte membrane protein band 4.1-like 3
chr3_+_101546827 10.89 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr5_-_130970723 10.84 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
Rap guanine nucleotide exchange factor (GEF) 6
chr7_+_134551583 10.76 ENST00000435928.1
caldesmon 1
chr4_+_71337834 10.76 ENST00000304887.5
mucin 7, secreted
chr1_-_9129735 10.69 ENST00000377424.4
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_-_52761262 10.67 ENST00000257901.3
keratin 85
chr12_+_124155652 10.61 ENST00000426174.2
ENST00000303372.5
tectonic family member 2
chr4_+_48018781 10.56 ENST00000295461.5
NIPA-like domain containing 1
chr18_+_39766626 10.21 ENST00000593234.1
ENST00000585627.1
ENST00000591199.1
ENST00000586990.1
ENST00000593051.1
ENST00000593316.1
ENST00000591381.1
ENST00000585639.1
ENST00000589068.1
long intergenic non-protein coding RNA 907
chr5_-_107703556 10.20 ENST00000496714.1
F-box and leucine-rich repeat protein 17
chrX_-_99987088 10.19 ENST00000372981.1
ENST00000263033.5
synaptotagmin-like 4
chr8_-_125486755 10.17 ENST00000499418.2
ENST00000530778.1
RNF139 antisense RNA 1 (head to head)
chr1_-_150669604 9.86 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr9_+_82188077 9.69 ENST00000425506.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_+_9296279 9.66 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr1_+_209859510 9.63 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_+_21967137 9.53 ENST00000441769.2
chromosome 9 open reading frame 53
chr21_+_39644214 9.45 ENST00000438657.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr10_+_75545391 9.34 ENST00000604524.1
ENST00000605216.1
ENST00000398706.2
zinc finger, SWIM-type containing 8
chr12_+_8995832 9.34 ENST00000541459.1
alpha-2-macroglobulin-like 1
chr21_+_35736302 9.31 ENST00000290310.3
potassium voltage-gated channel, Isk-related family, member 2
chrX_+_135570046 9.29 ENST00000370648.3
bombesin-like receptor 3
chr7_+_108210012 8.83 ENST00000249356.3
DnaJ (Hsp40) homolog, subfamily B, member 9
chr6_+_25754927 8.82 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr6_+_27775899 8.81 ENST00000358739.3
histone cluster 1, H2ai
chr18_-_53253112 8.76 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
transcription factor 4
chr10_+_75545329 8.58 ENST00000604729.1
ENST00000603114.1
zinc finger, SWIM-type containing 8
chr16_+_30669720 8.45 ENST00000356166.6
fibrosin
chr6_+_118869452 8.45 ENST00000357525.5
phospholamban
chr2_-_157198860 8.43 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr1_-_242162375 8.40 ENST00000357246.3
microtubule-associated protein 1 light chain 3 gamma
chr18_-_53253323 8.34 ENST00000540999.1
ENST00000563888.2
transcription factor 4
chr11_-_132813566 8.25 ENST00000331898.7
opioid binding protein/cell adhesion molecule-like
chr3_+_122296465 8.24 ENST00000483793.1
poly (ADP-ribose) polymerase family, member 15
chr3_-_58613323 8.18 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr8_-_95220775 8.08 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr11_-_104480019 8.07 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chr1_-_237167718 8.00 ENST00000464121.2
metallothionein 1H-like 1
chr21_+_39644172 7.93 ENST00000398932.1
potassium inwardly-rectifying channel, subfamily J, member 15
chrM_+_4431 7.90 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chr13_-_33112823 7.87 ENST00000504114.1
NEDD4 binding protein 2-like 2
chr13_-_28545276 7.86 ENST00000381020.7
caudal type homeobox 2
chr5_+_94890840 7.83 ENST00000504763.1
arylsulfatase family, member K
chr21_+_39644305 7.82 ENST00000398930.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_152635854 7.81 ENST00000368784.1
late cornified envelope 2D
chr6_-_27775694 7.78 ENST00000377401.2
histone cluster 1, H2bl
chr20_+_16729003 7.78 ENST00000246081.2
otoraplin
chr15_+_45879534 7.75 ENST00000564080.1
ENST00000562384.1
ENST00000569076.1
ENST00000566753.1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr12_-_11548496 7.68 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr4_-_153601136 7.37 ENST00000504064.1
ENST00000304385.3
transmembrane protein 154
chr1_-_152386732 7.32 ENST00000271835.3
cornulin
chr11_+_101785727 7.30 ENST00000263468.8
KIAA1377
chr12_+_130646999 7.29 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chrX_+_65382381 7.22 ENST00000519389.1
hephaestin
chr12_-_52828147 7.19 ENST00000252245.5
keratin 75
chr1_+_202317815 7.18 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr6_+_26521948 7.06 ENST00000411553.1
HLA complex group 11 (non-protein coding)
chr6_-_100442077 7.01 ENST00000281806.2
ENST00000369212.2
melanin-concentrating hormone receptor 2
chr2_+_166428839 6.95 ENST00000342316.4
cysteine-serine-rich nuclear protein 3
chr4_-_174320687 6.93 ENST00000296506.3
stimulator of chondrogenesis 1
chr17_-_42580738 6.93 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
G patch domain containing 8
chrX_+_65384052 6.91 ENST00000336279.5
ENST00000458621.1
hephaestin
chr6_-_116447283 6.87 ENST00000452729.1
ENST00000243222.4
collagen, type X, alpha 1
chrX_+_65384182 6.86 ENST00000441993.2
ENST00000419594.1
hephaestin
chr7_+_134464376 6.85 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr6_-_39902185 6.82 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
molybdenum cofactor synthesis 1
chr14_+_75761099 6.81 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5
chr9_-_100000957 6.80 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
chr3_-_58563094 6.77 ENST00000464064.1
family with sequence similarity 107, member A
chr3_-_114477962 6.75 ENST00000471418.1
zinc finger and BTB domain containing 20
chr9_-_130829588 6.69 ENST00000373078.4
nuclear apoptosis inducing factor 1
chr3_-_114477787 6.65 ENST00000464560.1
zinc finger and BTB domain containing 20
chr4_-_174451370 6.54 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr14_-_21492113 6.48 ENST00000554094.1
NDRG family member 2
chr11_+_76745385 6.46 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr12_-_18243075 6.43 ENST00000536890.1
RERG/RAS-like
chr16_+_23652773 6.39 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
dynactin 5 (p25)
chrX_+_65382433 6.36 ENST00000374727.3
hephaestin
chr12_-_18243119 6.32 ENST00000538724.1
ENST00000229002.2
RERG/RAS-like
chr11_+_63606373 6.30 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MAP/microtubule affinity-regulating kinase 2
chr1_+_151735431 6.21 ENST00000321531.5
ENST00000315067.8
ornithine decarboxylase antizyme 3
chr1_+_12976450 6.17 ENST00000361079.2
PRAME family member 7
chr15_+_45879321 6.14 ENST00000220531.3
ENST00000567461.1
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr2_-_89292422 6.14 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_23243156 6.11 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr7_-_5553369 6.10 ENST00000453700.3
ENST00000382368.3
F-box and leucine-rich repeat protein 18
chr10_-_62332357 6.06 ENST00000503366.1
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_90248739 6.05 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr5_+_140749803 5.96 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr22_+_41956767 5.96 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr17_-_29624343 5.94 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr16_-_20339123 5.92 ENST00000381360.5
glycoprotein 2 (zymogen granule membrane)
chr4_+_71226468 5.92 ENST00000226460.4
submaxillary gland androgen regulated protein 3A
chr1_+_52682052 5.87 ENST00000371591.1
zinc finger, FYVE domain containing 9
chr2_+_66662510 5.86 ENST00000272369.9
ENST00000407092.2
Meis homeobox 1
chr18_-_53070913 5.82 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr4_-_39033963 5.81 ENST00000381938.3
transmembrane protein 156
chr19_-_5903714 5.76 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr1_+_150898812 5.74 ENST00000271640.5
ENST00000448029.1
ENST00000368962.2
ENST00000534805.1
ENST00000368969.4
ENST00000368963.1
ENST00000498193.1
SET domain, bifurcated 1
chr16_+_12070567 5.71 ENST00000566228.1
sorting nexin 29
chr3_-_38835501 5.69 ENST00000449082.2
sodium channel, voltage-gated, type X, alpha subunit
chr12_-_58220078 5.57 ENST00000549039.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr2_+_90198535 5.55 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr14_+_75536335 5.53 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
zinc finger, C2HC-type containing 1C
chr17_-_74449252 5.52 ENST00000319380.7
ubiquitin-conjugating enzyme E2O
chr2_+_16080659 5.50 ENST00000281043.3
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chrX_-_3264682 5.48 ENST00000217939.6
matrix-remodelling associated 5
chr3_-_114790179 5.48 ENST00000462705.1
zinc finger and BTB domain containing 20
chr12_-_11508520 5.46 ENST00000545626.1
ENST00000500254.2
proline-rich protein BstNI subfamily 1
chr5_+_175511859 5.45 ENST00000503724.2
ENST00000253490.4
family with sequence similarity 153, member B
chr1_+_26485511 5.44 ENST00000374268.3
family with sequence similarity 110, member D
chr7_-_137028534 5.42 ENST00000348225.2
pleiotrophin
chr3_-_155461515 5.38 ENST00000399242.2
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr17_+_7211656 5.36 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr1_+_152627927 5.35 ENST00000444515.1
ENST00000536536.1
long intergenic non-protein coding RNA 302
chr14_-_21492251 5.33 ENST00000554398.1
NDRG family member 2
chr21_+_39644395 5.31 ENST00000398934.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_149546334 5.24 ENST00000231656.8
caudal type homeobox 1
chr7_+_40174565 5.24 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
succinylCoA:glutarate-CoA transferase
chr17_-_62340581 5.17 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
testis expressed 2
chr2_-_209010874 5.08 ENST00000260988.4
crystallin, gamma B
chr9_-_95640218 5.02 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
zinc finger protein 484
chr12_-_8814669 5.02 ENST00000535411.1
ENST00000540087.1
microfibrillar associated protein 5
chr6_+_72922505 5.01 ENST00000401910.3
regulating synaptic membrane exocytosis 1
chr2_-_206950781 5.01 ENST00000403263.1
INO80 complex subunit D
chr16_-_20338748 5.00 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
glycoprotein 2 (zymogen granule membrane)
chr7_-_19157248 4.98 ENST00000242261.5
twist family bHLH transcription factor 1
chrX_+_107683096 4.96 ENST00000328300.6
ENST00000361603.2
collagen, type IV, alpha 5
chr2_-_152382500 4.95 ENST00000434685.1
nebulin
chr5_-_137475071 4.91 ENST00000265191.2
NME/NM23 family member 5
chrX_+_84499038 4.89 ENST00000373165.3
zinc finger protein 711
chr4_+_88720698 4.87 ENST00000226284.5
integrin-binding sialoprotein
chr14_-_61748550 4.83 ENST00000555868.1
transmembrane protein 30B
chr9_-_123812542 4.83 ENST00000223642.1
complement component 5
chrX_+_21857764 4.81 ENST00000365779.2
membrane-bound transcription factor peptidase, site 2
chr1_+_153003671 4.81 ENST00000307098.4
small proline-rich protein 1B
chr10_-_13523073 4.79 ENST00000440282.1
BEN domain containing 7
chr20_+_52105495 4.79 ENST00000439873.2
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr1_+_192544857 4.77 ENST00000367459.3
ENST00000469578.2
regulator of G-protein signaling 1
chr6_+_72922590 4.76 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr6_+_163148973 4.74 ENST00000366888.2
PARK2 co-regulated
chr2_-_89399845 4.71 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr13_-_33112899 4.64 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
NEDD4 binding protein 2-like 2
chr13_-_38172863 4.63 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr3_+_169629354 4.52 ENST00000428432.2
ENST00000335556.3
sterile alpha motif domain containing 7

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC10_HOXD13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
16.4 196.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
9.5 28.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
6.3 18.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
5.3 15.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
4.7 23.7 GO:0048478 replication fork protection(GO:0048478)
4.4 17.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
4.4 26.3 GO:0051012 microtubule sliding(GO:0051012)
4.1 20.4 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
3.9 31.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
3.9 15.7 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
3.3 9.9 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
3.3 13.1 GO:0014807 regulation of somitogenesis(GO:0014807)
3.1 37.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
2.9 14.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
2.8 8.5 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
2.8 8.4 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
2.5 5.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
2.3 9.3 GO:1902159 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
2.2 56.1 GO:0001502 cartilage condensation(GO:0001502)
2.2 4.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
2.2 15.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
2.2 8.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.0 8.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.9 5.7 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
1.7 5.0 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
1.6 6.5 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.6 4.7 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.6 11.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.5 4.5 GO:1990641 response to iron ion starvation(GO:1990641)
1.5 7.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.4 23.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.4 4.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
1.4 11.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
1.4 5.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.4 8.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.3 10.6 GO:0015693 magnesium ion transport(GO:0015693)
1.3 3.9 GO:0002384 hepatic immune response(GO:0002384) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
1.2 6.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.2 5.0 GO:0007525 somatic muscle development(GO:0007525)
1.2 6.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
1.2 3.5 GO:0014028 mesoderm migration involved in gastrulation(GO:0007509) notochord formation(GO:0014028)
1.1 5.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.1 28.7 GO:0006825 copper ion transport(GO:0006825)
1.1 3.2 GO:0072092 ureteric bud invasion(GO:0072092)
1.1 13.9 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
1.1 2.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
1.1 3.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.0 7.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
1.0 9.3 GO:0008343 adult feeding behavior(GO:0008343)
1.0 2.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.0 8.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.0 6.0 GO:0001692 histamine metabolic process(GO:0001692)
0.9 3.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.9 4.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.9 3.5 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.9 2.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.9 15.7 GO:0031297 replication fork processing(GO:0031297)
0.9 8.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.8 11.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.8 2.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.8 4.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.8 61.5 GO:0030574 collagen catabolic process(GO:0030574)
0.8 6.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.7 4.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.7 12.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.7 1.5 GO:0048867 stem cell fate determination(GO:0048867)
0.7 2.1 GO:0021779 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.7 2.1 GO:0061056 sclerotome development(GO:0061056)
0.7 3.5 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.7 11.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.7 30.5 GO:0010107 potassium ion import(GO:0010107)
0.7 2.0 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.7 5.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.7 4.0 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.6 5.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.6 3.8 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.6 34.0 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.6 10.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.6 8.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 1.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.6 2.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.6 9.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 5.7 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.6 2.8 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.6 10.1 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.6 3.9 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 2.2 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) response to high density lipoprotein particle(GO:0055099) T cell extravasation(GO:0072683) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.5 2.2 GO:1901205 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.5 2.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 3.2 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.5 1.6 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.5 5.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5 8.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5 24.7 GO:0018149 peptide cross-linking(GO:0018149)
0.5 3.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.5 3.9 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.5 5.8 GO:0006776 vitamin A metabolic process(GO:0006776)
0.5 5.8 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.5 2.3 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.5 1.4 GO:1904252 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) negative regulation of bile acid biosynthetic process(GO:0070858) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.5 9.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.4 2.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.4 2.6 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.4 1.7 GO:0003335 corneocyte development(GO:0003335)
0.4 2.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.4 4.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 8.1 GO:0071420 cellular response to histamine(GO:0071420)
0.4 3.2 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.4 8.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.4 1.6 GO:0061743 motor learning(GO:0061743)
0.4 3.8 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 1.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4 34.9 GO:0070268 cornification(GO:0070268)
0.4 2.3 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.4 4.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.4 1.5 GO:0070459 prolactin secretion(GO:0070459)
0.4 1.8 GO:0001555 oocyte growth(GO:0001555)
0.4 0.7 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.3 3.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 3.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 12.1 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.3 1.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 3.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 10.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 3.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.3 6.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 2.7 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.3 1.3 GO:0030259 lipid glycosylation(GO:0030259)
0.3 3.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.3 4.9 GO:0006183 GTP biosynthetic process(GO:0006183)
0.3 3.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 0.9 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 4.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.3 1.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 3.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.3 3.8 GO:0046325 negative regulation of glucose import(GO:0046325)
0.3 10.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.3 1.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.3 2.0 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.3 2.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 4.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 13.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.3 3.4 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.3 12.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 2.0 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.2 42.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.2 12.4 GO:0007517 muscle organ development(GO:0007517)
0.2 4.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 6.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.2 3.7 GO:0005513 detection of calcium ion(GO:0005513)
0.2 14.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 3.9 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.2 10.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 3.9 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.2 1.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 3.6 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.2 4.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 0.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.4 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.2 1.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 2.9 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.2 1.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 2.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 0.5 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.2 1.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 0.5 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.2 40.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 5.9 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.2 1.9 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 3.6 GO:0006937 regulation of muscle contraction(GO:0006937)
0.2 12.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 6.6 GO:0009994 oocyte differentiation(GO:0009994)
0.1 0.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.8 GO:0051775 response to redox state(GO:0051775)
0.1 0.8 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 3.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 3.0 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 3.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 1.2 GO:0015705 iodide transport(GO:0015705)
0.1 1.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 2.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 7.3 GO:0016266 O-glycan processing(GO:0016266)
0.1 5.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 3.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 4.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 6.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 1.8 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.7 GO:0034378 chylomicron assembly(GO:0034378)
0.1 5.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 2.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.1 GO:0045471 response to ethanol(GO:0045471)
0.1 0.8 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 2.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 3.4 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.3 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1 3.1 GO:0035904 aorta development(GO:0035904)
0.1 2.3 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.1 12.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 11.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 3.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.8 GO:0060736 prostate gland growth(GO:0060736)
0.1 5.1 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.9 GO:0016048 detection of temperature stimulus(GO:0016048)
0.1 1.4 GO:0060292 long term synaptic depression(GO:0060292)
0.1 6.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.9 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 1.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.4 GO:0035137 hindlimb morphogenesis(GO:0035137)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 1.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 2.9 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 2.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 1.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.9 GO:0036258 multivesicular body assembly(GO:0036258)
0.0 1.3 GO:0050890 cognition(GO:0050890)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 2.3 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 1.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.9 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 4.6 GO:0016197 endosomal transport(GO:0016197)
0.0 0.5 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 2.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.9 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.0 1.1 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 4.4 GO:0030198 extracellular matrix organization(GO:0030198)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
16.1 225.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
11.3 34.0 GO:0044609 DBIRD complex(GO:0044609)
3.9 11.7 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
3.7 11.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
3.6 10.8 GO:0097679 other organism cytoplasm(GO:0097679)
2.7 41.1 GO:0030478 actin cap(GO:0030478)
2.6 15.9 GO:1990037 Lewy body core(GO:1990037)
2.5 24.7 GO:0098651 basement membrane collagen trimer(GO:0098651)
2.2 15.7 GO:0033269 internode region of axon(GO:0033269)
2.1 26.8 GO:0005577 fibrinogen complex(GO:0005577)
1.2 4.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.0 3.9 GO:0036449 microtubule minus-end(GO:0036449)
1.0 3.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.9 15.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.8 35.1 GO:0045095 keratin filament(GO:0045095)
0.8 13.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.8 10.6 GO:0036038 MKS complex(GO:0036038)
0.7 12.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.7 10.5 GO:0043194 axon initial segment(GO:0043194)
0.6 11.0 GO:0033270 paranode region of axon(GO:0033270)
0.6 5.7 GO:0071439 clathrin complex(GO:0071439)
0.6 6.3 GO:0097427 microtubule bundle(GO:0097427)
0.6 28.1 GO:0043596 nuclear replication fork(GO:0043596)
0.5 4.8 GO:0005579 membrane attack complex(GO:0005579)
0.5 93.5 GO:0032993 protein-DNA complex(GO:0032993)
0.5 24.4 GO:0001533 cornified envelope(GO:0001533)
0.5 6.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.4 5.4 GO:0005642 annulate lamellae(GO:0005642)
0.4 2.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.4 34.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.4 3.8 GO:0016013 syntrophin complex(GO:0016013)
0.4 1.7 GO:0033186 CAF-1 complex(GO:0033186)
0.4 2.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 1.2 GO:0000806 Y chromosome(GO:0000806)
0.3 3.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.3 5.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 7.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.3 3.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 2.3 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.3 124.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 28.9 GO:0072686 mitotic spindle(GO:0072686)
0.3 8.5 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.3 0.9 GO:0033565 ESCRT-0 complex(GO:0033565)
0.3 2.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.3 2.3 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.3 28.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 3.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 6.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 8.4 GO:0000421 autophagosome membrane(GO:0000421)
0.3 2.8 GO:0042788 polysomal ribosome(GO:0042788)
0.3 6.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 11.0 GO:0048786 presynaptic active zone(GO:0048786)
0.2 4.7 GO:0097225 sperm midpiece(GO:0097225)
0.2 1.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 28.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 8.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 2.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.2 20.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 4.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 3.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 34.2 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 3.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 1.1 GO:0005883 neurofilament(GO:0005883)
0.1 14.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 8.6 GO:0031672 A band(GO:0031672)
0.1 21.7 GO:0030426 growth cone(GO:0030426)
0.1 6.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 22.5 GO:0072562 blood microparticle(GO:0072562)
0.1 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 14.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 15.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.2 GO:0005871 kinesin complex(GO:0005871)
0.1 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.1 3.6 GO:0005902 microvillus(GO:0005902)
0.1 2.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.5 GO:0005581 collagen trimer(GO:0005581)
0.1 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 4.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 44.4 GO:0005615 extracellular space(GO:0005615)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.2 GO:0035579 specific granule membrane(GO:0035579)
0.0 4.0 GO:0030027 lamellipodium(GO:0030027)
0.0 5.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 4.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 38.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 7.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 3.4 GO:0016604 nuclear body(GO:0016604)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 81.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
6.2 30.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
4.0 16.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
3.2 29.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
3.2 9.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
3.1 226.6 GO:0050840 extracellular matrix binding(GO:0050840)
2.5 9.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
2.4 23.7 GO:0036310 annealing helicase activity(GO:0036310)
2.2 8.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.2 6.5 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
2.1 8.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
2.0 8.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
1.7 30.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.6 9.6 GO:0004882 androgen receptor activity(GO:0004882)
1.5 41.1 GO:0005523 tropomyosin binding(GO:0005523)
1.4 19.1 GO:0030280 structural constituent of epidermis(GO:0030280)
1.4 17.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.3 15.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.2 6.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.2 5.8 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
1.1 34.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.1 5.6 GO:0008420 CTD phosphatase activity(GO:0008420)
1.1 3.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
1.0 3.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.0 3.0 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.9 12.0 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.9 15.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.9 15.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.8 9.3 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.8 75.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.8 4.7 GO:0030492 hemoglobin binding(GO:0030492)
0.8 2.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.7 6.7 GO:0004969 histamine receptor activity(GO:0004969)
0.7 8.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.7 2.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.7 2.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 3.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.6 3.1 GO:0051373 FATZ binding(GO:0051373)
0.6 1.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.6 3.5 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.6 2.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.6 11.2 GO:0051787 misfolded protein binding(GO:0051787)
0.6 7.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.6 28.5 GO:0016504 peptidase activator activity(GO:0016504)
0.5 2.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 8.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 2.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 4.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.5 10.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.5 2.4 GO:0050436 microfibril binding(GO:0050436)
0.5 3.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.5 10.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 18.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.5 1.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.5 20.9 GO:0008009 chemokine activity(GO:0008009)
0.4 6.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 4.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.4 2.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.4 3.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 3.0 GO:0001515 opioid peptide activity(GO:0001515)
0.4 42.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4 3.8 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 2.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4 16.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 5.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 18.9 GO:0015485 cholesterol binding(GO:0015485)
0.4 2.7 GO:0005497 androgen binding(GO:0005497)
0.4 35.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 7.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 8.2 GO:0070403 NAD+ binding(GO:0070403)
0.3 1.3 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 3.7 GO:0039706 co-receptor binding(GO:0039706)
0.3 4.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 2.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 6.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 3.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 6.5 GO:0002162 dystroglycan binding(GO:0002162)
0.3 5.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 3.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.3 2.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 9.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.3 5.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 1.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 1.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 6.0 GO:0042166 acetylcholine binding(GO:0042166)
0.3 12.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.9 GO:0004064 arylesterase activity(GO:0004064)
0.2 4.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 3.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 5.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.9 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 5.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 5.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 22.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 8.6 GO:0070888 E-box binding(GO:0070888)
0.2 9.1 GO:0030507 spectrin binding(GO:0030507)
0.2 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 5.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 5.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 2.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 2.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 12.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 3.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 33.0 GO:0003823 antigen binding(GO:0003823)
0.1 0.7 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 3.4 GO:0005521 lamin binding(GO:0005521)
0.1 13.9 GO:0019905 syntaxin binding(GO:0019905)
0.1 6.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.0 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 2.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 6.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 2.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 2.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 3.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 3.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 18.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.6 GO:0048018 receptor agonist activity(GO:0048018)
0.1 3.2 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 7.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 7.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 3.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 12.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 3.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 4.0 GO:0005518 collagen binding(GO:0005518)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.0 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 20.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 16.8 GO:0008017 microtubule binding(GO:0008017)
0.1 6.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 3.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 7.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 3.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 8.3 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 2.2 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.1 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 4.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 4.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 7.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 3.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 3.8 GO:0005178 integrin binding(GO:0005178)
0.0 8.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 6.1 GO:0017171 serine hydrolase activity(GO:0017171)
0.0 2.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 10.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 4.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.4 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.6 GO:0019838 growth factor binding(GO:0019838)
0.0 1.7 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 3.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0005548 phospholipid transporter activity(GO:0005548)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 262.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
1.4 58.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
1.3 62.0 NABA COLLAGENS Genes encoding collagen proteins
0.8 13.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8 3.2 PID IL3 PATHWAY IL3-mediated signaling events
0.7 84.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.5 30.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.5 6.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.4 12.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 5.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.3 58.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 7.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 17.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 8.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 2.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 6.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 9.7 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.0 ST GA12 PATHWAY G alpha 12 Pathway
0.1 3.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 6.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 4.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 12.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 20.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 14.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.6 PID IL27 PATHWAY IL27-mediated signaling events
0.1 25.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 2.7 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 2.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 9.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 196.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.5 79.5 REACTOME MYOGENESIS Genes involved in Myogenesis
1.4 24.6 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
1.1 27.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.1 72.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
1.0 24.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.0 62.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.9 30.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.7 7.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 6.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.6 11.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.5 9.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 8.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.4 3.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 6.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 29.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 6.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 10.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 11.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.3 11.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.3 3.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 3.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 12.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 8.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 48.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 4.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 3.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 5.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 13.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 3.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 2.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 3.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 2.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 6.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 2.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 6.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 7.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.8 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 10.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 6.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 3.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 3.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 6.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 6.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 3.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides