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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HOXC9

Z-value: 0.92

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Transcription factors associated with HOXC9

Gene Symbol Gene ID Gene Info
HOXC9
ENSG00000180806.4 homeobox C9

Activity profile of HOXC9 motif

Sorted Z-values of HOXC9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_81083890 10.44 ENST00000518937.1
TPD52
tumor protein D52
chrX_-_13835147 9.58 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr6_-_52859046 8.25 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr9_+_137979506 6.85 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr1_+_149230680 6.54 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr18_+_32558208 6.30 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr8_+_132916318 6.22 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr2_+_187371440 6.09 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr1_+_163039143 6.08 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
RGS4
regulator of G-protein signaling 4
chr13_-_24007815 5.71 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr8_-_80993010 5.65 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr7_+_64838712 5.55 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr11_+_19798964 5.30 ENST00000527559.2
NAV2
neuron navigator 2
chr7_+_64838786 5.24 ENST00000450302.2
ZNF92
zinc finger protein 92
chr10_-_13344341 5.13 ENST00000396920.3
PHYH
phytanoyl-CoA 2-hydroxylase
chr1_+_220863187 4.85 ENST00000294889.5
C1orf115
chromosome 1 open reading frame 115
chr14_+_53173910 4.84 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr14_+_53173890 4.76 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr2_-_224467093 4.73 ENST00000305409.2
SCG2
secretogranin II
chr17_+_48823975 4.73 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr11_+_46366918 4.73 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr12_-_30887948 4.56 ENST00000433722.2
CAPRIN2
caprin family member 2
chr9_-_93405352 4.55 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr9_-_95055956 4.53 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr9_-_95056010 4.44 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr1_-_197115818 4.33 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr12_+_19358228 4.21 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr6_+_158733692 4.17 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr8_+_104033296 4.13 ENST00000521514.1
ENST00000518738.1
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr4_+_70894130 4.08 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr16_-_66764119 4.05 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr12_-_90049878 3.86 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr6_-_52859968 3.82 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr1_-_212965104 3.76 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr12_-_90049828 3.70 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr2_-_69664586 3.62 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr7_+_130126165 3.61 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr12_-_118628350 3.58 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr11_-_107729887 3.41 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr19_-_20748541 3.38 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr13_-_30424821 3.35 ENST00000380680.4
UBL3
ubiquitin-like 3
chr3_+_87276407 3.30 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
CHMP2B
charged multivesicular body protein 2B
chr2_-_172750733 3.24 ENST00000392592.4
ENST00000422440.2
SLC25A12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr8_-_17555164 3.22 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr9_+_80912059 3.18 ENST00000347159.2
ENST00000376588.3
PSAT1
phosphoserine aminotransferase 1
chr7_+_130126012 3.13 ENST00000341441.5
MEST
mesoderm specific transcript
chr8_-_81083731 3.10 ENST00000379096.5
TPD52
tumor protein D52
chr19_+_21265028 3.06 ENST00000291770.7
ZNF714
zinc finger protein 714
chr2_+_37571845 3.04 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr22_+_21133469 2.98 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr5_-_68665084 2.93 ENST00000509462.1
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr12_-_63328817 2.88 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr11_-_3400442 2.82 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chrX_+_105937068 2.82 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chrX_-_68385354 2.82 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr5_+_156696362 2.82 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_+_37571717 2.81 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr10_-_127505167 2.74 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr19_-_47975417 2.74 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_-_226926864 2.66 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr11_-_3400330 2.65 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
ZNF195
zinc finger protein 195
chr4_-_69215467 2.64 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr21_-_27423339 2.60 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr5_-_68665296 2.54 ENST00000512152.1
ENST00000503245.1
ENST00000512561.1
ENST00000380822.4
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr3_+_149191723 2.51 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr4_-_72649763 2.48 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr11_-_60674037 2.48 ENST00000541371.1
ENST00000227524.4
PRPF19
pre-mRNA processing factor 19
chr7_+_110731062 2.46 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr5_-_42811986 2.45 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr6_-_111804905 2.42 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_+_160590469 2.41 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr12_+_123237321 2.37 ENST00000280557.6
ENST00000455982.2
DENR
density-regulated protein
chrX_-_9734004 2.32 ENST00000467482.1
ENST00000380929.2
GPR143
G protein-coupled receptor 143
chrX_-_68385274 2.29 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr2_+_86669118 2.28 ENST00000427678.1
ENST00000542128.1
KDM3A
lysine (K)-specific demethylase 3A
chr9_-_21187598 2.25 ENST00000421715.1
IFNA4
interferon, alpha 4
chr8_+_104033277 2.24 ENST00000518857.1
ENST00000395862.3
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr14_-_21492113 2.17 ENST00000554094.1
NDRG2
NDRG family member 2
chr5_-_111093167 2.13 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr20_+_57414743 2.13 ENST00000313949.7
GNAS
GNAS complex locus
chr2_+_70121075 2.11 ENST00000409116.1
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr2_-_225811747 2.03 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr10_+_45495898 2.01 ENST00000298299.3
ZNF22
zinc finger protein 22
chr2_+_207630081 2.01 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr4_+_70916119 1.98 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr2_+_106468204 1.97 ENST00000425756.1
ENST00000393349.2
NCK2
NCK adaptor protein 2
chr9_+_2029019 1.95 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_140227048 1.95 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr11_-_128894053 1.93 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr10_-_73848086 1.88 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_+_69681710 1.87 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr10_+_115614370 1.87 ENST00000369301.3
NHLRC2
NHL repeat containing 2
chr10_-_73848531 1.84 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr16_+_56485402 1.81 ENST00000566157.1
ENST00000562150.1
ENST00000561646.1
ENST00000568397.1
OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr1_-_212004090 1.80 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr2_-_86850949 1.79 ENST00000237455.4
RNF103
ring finger protein 103
chr17_+_55162453 1.71 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr7_+_102937869 1.67 ENST00000249269.4
ENST00000428154.1
ENST00000420236.2
PMPCB
peptidase (mitochondrial processing) beta
chr12_+_20963647 1.63 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr20_+_57414795 1.61 ENST00000371098.2
ENST00000371075.3
GNAS
GNAS complex locus
chr1_-_19426149 1.59 ENST00000429347.2
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr17_-_9862772 1.56 ENST00000580865.1
ENST00000583882.1
GAS7
growth arrest-specific 7
chr16_+_22501658 1.52 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr9_-_179018 1.48 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr14_+_78174414 1.48 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SLIRP
SRA stem-loop interacting RNA binding protein
chr8_-_17579726 1.47 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr9_-_69262509 1.42 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr2_+_161993412 1.36 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr20_-_23860373 1.35 ENST00000304710.4
CST5
cystatin D
chr9_+_70856899 1.34 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chr9_+_131549610 1.30 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr6_-_109702885 1.28 ENST00000504373.1
CD164
CD164 molecule, sialomucin
chr2_-_17981462 1.28 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chrX_-_16887963 1.27 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr22_-_32651326 1.24 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr13_-_52027134 1.22 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chrX_+_120181457 1.21 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr12_-_124118296 1.20 ENST00000424014.2
ENST00000537073.1
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr15_-_55541227 1.18 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr3_+_138340049 1.17 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr7_-_22539771 1.17 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr12_-_10605929 1.16 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr12_-_110906027 1.15 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN3
GPN-loop GTPase 3
chr5_-_145562147 1.13 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr1_+_35734562 1.12 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr7_-_44122063 1.11 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM
polymerase (DNA directed), mu
chr12_+_20963632 1.09 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr4_+_71248795 1.06 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr4_-_103749313 1.05 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr9_+_103947311 1.04 ENST00000395056.2
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr9_-_70490107 1.04 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr4_+_155484103 1.02 ENST00000302068.4
FGB
fibrinogen beta chain
chr1_+_81771806 1.01 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr11_+_125496619 0.99 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr11_+_43333513 0.98 ENST00000534695.1
ENST00000455725.2
ENST00000531273.1
ENST00000420461.2
ENST00000378852.3
ENST00000534600.1
API5
apoptosis inhibitor 5
chr2_+_114195268 0.98 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr10_-_96829246 0.98 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr19_-_48894104 0.96 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr2_+_109204909 0.96 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_+_112709804 0.94 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr5_-_125930929 0.93 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr8_-_30670384 0.93 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr11_+_22688150 0.92 ENST00000454584.2
GAS2
growth arrest-specific 2
chr3_+_69812701 0.88 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr18_+_34124507 0.88 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr13_+_33160553 0.87 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr5_-_42812143 0.84 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr1_+_146714291 0.74 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr1_+_47603109 0.74 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr10_-_115614127 0.73 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr16_+_28505955 0.72 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
APOBR
apolipoprotein B receptor
chr6_+_13272904 0.71 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr2_+_103035102 0.71 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr5_-_135290705 0.69 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr4_-_103749105 0.67 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_+_73498898 0.67 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr2_+_202047596 0.66 ENST00000286186.6
ENST00000360132.3
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr19_+_21106081 0.65 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
ZNF85
zinc finger protein 85
chr2_+_109271481 0.64 ENST00000542845.1
ENST00000393314.2
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_8723918 0.63 ENST00000454224.1
AC011747.4
AC011747.4
chr11_+_89764274 0.62 ENST00000448984.1
ENST00000432771.1
TRIM49C
tripartite motif containing 49C
chr11_-_89541743 0.61 ENST00000329758.1
TRIM49
tripartite motif containing 49
chr2_-_70475701 0.59 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr9_+_131549483 0.59 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chr12_-_10573149 0.55 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3
killer cell lectin-like receptor subfamily C, member 3
chr3_-_38992052 0.55 ENST00000302328.3
ENST00000450244.1
ENST00000444237.2
SCN11A
sodium channel, voltage-gated, type XI, alpha subunit
chr12_-_104234966 0.55 ENST00000392876.3
NT5DC3
5'-nucleotidase domain containing 3
chr5_+_175288631 0.54 ENST00000509837.1
CPLX2
complexin 2
chr15_+_52155001 0.54 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr19_+_30433372 0.53 ENST00000312051.6
URI1
URI1, prefoldin-like chaperone
chr11_+_125496400 0.52 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr11_+_114310102 0.51 ENST00000265881.5
REXO2
RNA exonuclease 2
chrY_-_6740649 0.51 ENST00000383036.1
ENST00000383037.4
AMELY
amelogenin, Y-linked
chr4_+_88529681 0.50 ENST00000399271.1
DSPP
dentin sialophosphoprotein
chrX_+_41193407 0.50 ENST00000457138.2
ENST00000441189.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr17_-_40288449 0.50 ENST00000552162.1
ENST00000550504.1
RAB5C
RAB5C, member RAS oncogene family
chr19_-_54850417 0.49 ENST00000291759.4
LILRA4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
chr2_+_233390890 0.45 ENST00000258385.3
ENST00000536614.1
ENST00000457943.2
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr6_+_166945369 0.45 ENST00000598601.1
Z98049.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr2_+_109237717 0.45 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr15_-_90222642 0.44 ENST00000430628.2
PLIN1
perilipin 1
chr8_-_110986918 0.44 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr9_-_104198042 0.43 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr12_-_21757774 0.43 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr2_-_231989808 0.43 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr15_-_90222610 0.42 ENST00000300055.5
PLIN1
perilipin 1
chr12_-_27167233 0.41 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3
transmembrane 7 superfamily member 3
chrX_+_43515467 0.41 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr12_-_8803128 0.40 ENST00000543467.1
MFAP5
microfibrillar associated protein 5
chr12_-_11091862 0.39 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chrX_+_65382433 0.38 ENST00000374727.3
HEPH
hephaestin
chr7_+_141811539 0.38 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chr8_-_93029865 0.38 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_155484155 0.36 ENST00000509493.1
FGB
fibrinogen beta chain
chr17_+_58018269 0.34 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr5_-_16738451 0.34 ENST00000274203.9
ENST00000515803.1
MYO10
myosin X
chr4_-_69536346 0.33 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr6_-_88876058 0.33 ENST00000369501.2
CNR1
cannabinoid receptor 1 (brain)
chr4_-_103748880 0.33 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_+_71226468 0.31 ENST00000226460.4
SMR3A
submaxillary gland androgen regulated protein 3A

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
1.9 5.8 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.5 7.6 GO:1990034 calcium ion export from cell(GO:1990034)
1.3 5.3 GO:0021564 vagus nerve development(GO:0021564)
1.3 5.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
1.1 3.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.0 9.6 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 2.4 GO:0002188 translation reinitiation(GO:0002188)
0.8 6.8 GO:0003190 atrioventricular valve formation(GO:0003190)
0.8 2.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.7 4.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.7 2.7 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.6 3.2 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.6 2.3 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.5 3.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.5 2.6 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.4 3.0 GO:0008218 bioluminescence(GO:0008218)
0.4 1.3 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.4 5.5 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.4 2.5 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.4 3.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.4 2.0 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.4 9.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4 1.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4 2.7 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.4 1.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.4 12.1 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.4 1.5 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.4 5.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.4 2.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 2.0 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.3 4.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 2.8 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 1.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 1.7 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 1.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 2.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.2 GO:0033216 ferric iron import(GO:0033216)
0.2 4.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 1.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 6.4 GO:0090383 phagosome acidification(GO:0090383)
0.2 1.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 2.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 6.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 3.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 3.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 4.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2 22.0 GO:0030183 B cell differentiation(GO:0030183)
0.1 6.1 GO:0050832 defense response to fungus(GO:0050832)
0.1 6.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 2.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.9 GO:0042426 choline catabolic process(GO:0042426)
0.1 4.1 GO:0051642 centrosome localization(GO:0051642)
0.1 1.0 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 1.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.3 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 1.7 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.8 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 4.2 GO:0061512 protein localization to cilium(GO:0061512)
0.1 2.4 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 2.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 2.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.4 GO:0044320 cellular response to leptin stimulus(GO:0044320)
0.1 3.5 GO:0061458 reproductive system development(GO:0061458)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 2.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.2 GO:0016180 snRNA processing(GO:0016180)
0.1 0.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 6.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.2 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.7 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 6.2 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.7 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 5.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 2.5 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 3.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 1.2 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 1.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.5 GO:0034505 tooth mineralization(GO:0034505)
0.0 2.7 GO:0007498 mesoderm development(GO:0007498)
0.0 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.7 GO:0042476 odontogenesis(GO:0042476)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 1.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 4.1 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 2.7 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.8 5.7 GO:0070852 cell body fiber(GO:0070852)
0.8 9.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.8 3.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.7 5.5 GO:0070761 pre-snoRNP complex(GO:0070761)
0.6 4.3 GO:0036449 microtubule minus-end(GO:0036449)
0.5 2.5 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.5 5.3 GO:0005614 interstitial matrix(GO:0005614)
0.5 10.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 7.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 1.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 6.8 GO:0044295 axonal growth cone(GO:0044295)
0.3 2.6 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.3 3.3 GO:0000815 ESCRT III complex(GO:0000815)
0.2 4.7 GO:0031045 dense core granule(GO:0031045)
0.2 6.3 GO:0035371 microtubule plus-end(GO:0035371)
0.2 4.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.2 3.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 2.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 1.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 4.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.3 GO:0031265 death-inducing signaling complex(GO:0031264) CD95 death-inducing signaling complex(GO:0031265)
0.1 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 4.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.6 GO:0097165 nuclear stress granule(GO:0097165)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.5 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.1 1.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 5.3 GO:1904724 specific granule lumen(GO:0035580) tertiary granule lumen(GO:1904724)
0.1 3.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 6.7 GO:0043197 dendritic spine(GO:0043197)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 4.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.7 GO:0042627 chylomicron(GO:0042627)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 24.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 8.6 GO:0045121 membrane raft(GO:0045121)
0.0 1.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 4.3 GO:0030027 lamellipodium(GO:0030027)
0.0 3.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 5.5 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.7 GO:0005874 microtubule(GO:0005874)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.7 GO:0005929 cilium(GO:0005929)
0.0 1.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.9 5.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.1 6.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.9 9.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.6 3.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 2.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.4 4.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 5.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4 1.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.3 3.7 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 6.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.3 1.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 1.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 2.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 5.7 GO:0070628 proteasome binding(GO:0070628)
0.3 4.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 7.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 2.6 GO:0051425 PTB domain binding(GO:0051425)
0.2 12.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 1.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.2 1.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.2 1.3 GO:0005499 vitamin D binding(GO:0005499)
0.2 6.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 2.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 4.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 1.0 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.2 2.3 GO:0035240 dopamine binding(GO:0035240)
0.2 1.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 2.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 2.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 3.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 4.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 3.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.0 GO:0008483 transaminase activity(GO:0008483)
0.1 3.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 2.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.2 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.4 GO:0043022 ribosome binding(GO:0043022)
0.0 1.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 2.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 3.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 6.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 7.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 5.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 21.0 GO:0008270 zinc ion binding(GO:0008270)
0.0 14.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 5.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 5.9 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 3.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 3.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.3 GO:0002020 protease binding(GO:0002020)
0.0 3.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0016248 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.4 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 7.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 1.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.5 PID MYC PATHWAY C-MYC pathway
0.1 3.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 10.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID ARF 3PATHWAY Arf1 pathway
0.0 3.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 5.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 10.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 19.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 6.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 9.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 5.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 8.9 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.1 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 5.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 4.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 2.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 3.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 7.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 3.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 9.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits