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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for HSFY2

Z-value: 1.08

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Transcription factors associated with HSFY2

Gene Symbol Gene ID Gene Info
ENSG00000169953.11 heat shock transcription factor Y-linked 2

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_30327063 19.65 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr2_-_169769787 19.47 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr13_+_37581115 17.12 ENST00000481013.1
exosome component 8
chr1_-_197115818 16.19 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr3_-_185641681 15.26 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chrX_+_155110956 13.92 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr8_+_22224811 13.48 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr3_-_52569023 12.30 ENST00000307076.4
5'-nucleotidase domain containing 2
chr2_+_201170770 11.83 ENST00000409988.3
ENST00000409385.1
spermatogenesis associated, serine-rich 2-like
chr4_-_100871506 11.70 ENST00000296417.5
H2A histone family, member Z
chr5_+_159848854 11.09 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr2_+_74056147 10.55 ENST00000394070.2
ENST00000536064.1
STAM binding protein
chr14_+_20923350 10.46 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr21_-_40720995 10.35 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr1_-_150207017 10.07 ENST00000369119.3
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr10_+_17272608 9.95 ENST00000421459.2
vimentin
chr15_+_41624892 9.82 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
nucleolar and spindle associated protein 1
chr2_-_10952832 9.79 ENST00000540494.1
protein disulfide isomerase family A, member 6
chr2_+_201170596 9.60 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr21_-_40720974 9.59 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr3_-_146262365 9.28 ENST00000448787.2
phospholipid scramblase 1
chr12_+_66217911 8.99 ENST00000403681.2
high mobility group AT-hook 2
chr11_+_101983176 8.98 ENST00000524575.1
Yes-associated protein 1
chr1_-_149900122 8.92 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr4_+_113558272 8.72 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr3_-_146262428 8.66 ENST00000486631.1
phospholipid scramblase 1
chr16_-_50402836 8.66 ENST00000394688.3
bromodomain containing 7
chr5_+_76114758 8.61 ENST00000514165.1
ENST00000296677.4
coagulation factor II (thrombin) receptor-like 1
chr1_+_155583012 8.59 ENST00000462250.2
misato 1, mitochondrial distribution and morphology regulator
chr12_-_50419177 8.58 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
Rac GTPase activating protein 1
chr1_-_193029192 8.44 ENST00000417752.1
ENST00000367452.4
ubiquitin carboxyl-terminal hydrolase L5
chr16_-_50402690 8.44 ENST00000394689.2
bromodomain containing 7
chr8_+_104310661 8.33 ENST00000522566.1
frizzled family receptor 6
chr1_+_111991474 8.17 ENST00000369722.3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr2_+_74056066 8.10 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAM binding protein
chr17_+_1733276 8.08 ENST00000254719.5
replication protein A1, 70kDa
chr17_-_8113542 8.03 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr17_-_46178741 7.99 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr11_-_77850629 7.92 ENST00000376156.3
ENST00000525870.1
ENST00000530454.1
ENST00000525755.1
ENST00000527099.1
ENST00000525761.1
ENST00000299626.5
ALG8, alpha-1,3-glucosyltransferase
chr18_+_12308046 7.87 ENST00000317702.5
tubulin, beta 6 class V
chrX_+_49028265 7.81 ENST00000376322.3
ENST00000376327.5
proteolipid protein 2 (colonic epithelium-enriched)
chr17_-_38574169 7.77 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr22_+_42017987 7.75 ENST00000405506.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr2_+_27851863 7.74 ENST00000264718.3
ENST00000610189.1
GPN-loop GTPase 1
chr3_-_146262352 7.73 ENST00000462666.1
phospholipid scramblase 1
chr1_-_94344754 7.14 ENST00000436063.2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr17_+_18625336 7.03 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
tripartite motif containing 16-like
chr8_+_48920960 6.95 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr15_-_41624685 6.85 ENST00000560640.1
ENST00000220514.3
Opa interacting protein 5
chr2_+_39005336 6.85 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr5_+_65440032 6.80 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr1_-_89458415 6.80 ENST00000321792.5
ENST00000370491.3
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr2_+_192141611 6.70 ENST00000392316.1
myosin IB
chr2_+_219110149 6.69 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chr2_+_27435734 6.69 ENST00000419744.1
all-trans retinoic acid-induced differentiation factor
chr8_-_74206673 6.62 ENST00000396465.1
ribosomal protein L7
chr14_+_39583427 6.60 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chr2_+_201754050 6.55 ENST00000426253.1
ENST00000416651.1
ENST00000454952.1
ENST00000409020.1
ENST00000359683.4
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr8_-_66546439 6.37 ENST00000276569.3
armadillo repeat containing 1
chr8_-_74206133 6.26 ENST00000352983.2
ribosomal protein L7
chr17_-_7590745 6.26 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
tumor protein p53
chr3_-_146262293 6.24 ENST00000448205.1
phospholipid scramblase 1
chr1_-_110950255 6.20 ENST00000483260.1
ENST00000474861.2
ENST00000602318.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr13_+_53030107 6.13 ENST00000490903.1
ENST00000480747.1
cytoskeleton associated protein 2
chr10_-_27443294 6.02 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
YME1-like 1 ATPase
chr16_+_81040103 5.99 ENST00000305850.5
ENST00000299572.5
centromere protein N
chr19_+_57874835 5.95 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr5_-_37371278 5.89 ENST00000231498.3
nucleoporin 155kDa
chrX_-_53461288 5.85 ENST00000375298.4
ENST00000375304.5
hydroxysteroid (17-beta) dehydrogenase 10
chr7_-_93520259 5.82 ENST00000222543.5
tissue factor pathway inhibitor 2
chr4_-_106629796 5.74 ENST00000416543.1
ENST00000515819.1
ENST00000420368.2
ENST00000503746.1
ENST00000340139.5
ENST00000433009.1
integrator complex subunit 12
chr7_-_7679633 5.74 ENST00000401447.1
replication protein A3, 14kDa
chr3_+_23847394 5.63 ENST00000306627.3
ubiquitin-conjugating enzyme E2E 1
chr2_-_136633940 5.61 ENST00000264156.2
minichromosome maintenance complex component 6
chr15_+_48623600 5.58 ENST00000558813.1
ENST00000331200.3
ENST00000558472.1
deoxyuridine triphosphatase
chr12_+_75874460 5.57 ENST00000266659.3
GLI pathogenesis-related 1
chr1_+_158900568 5.51 ENST00000458222.1
pyrin and HIN domain family, member 1
chr4_-_104119528 5.41 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr12_-_6961050 5.32 ENST00000538862.2
cell division cycle associated 3
chr2_-_84686552 5.30 ENST00000393868.2
succinate-CoA ligase, alpha subunit
chr1_-_6453426 5.28 ENST00000545482.1
acyl-CoA thioesterase 7
chr7_-_93520191 5.16 ENST00000545378.1
tissue factor pathway inhibitor 2
chr1_+_202830876 5.13 ENST00000456105.2
RP11-480I12.7
chr1_+_19578033 5.10 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr10_+_12238171 5.09 ENST00000378900.2
ENST00000442050.1
cell division cycle 123
chr18_+_3247779 5.00 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_10658489 5.00 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr3_-_148804275 4.88 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr2_-_55496344 4.87 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr18_+_9103957 4.86 ENST00000400033.1
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr6_-_114292449 4.81 ENST00000519065.1
histone deacetylase 2
chr18_+_57567180 4.81 ENST00000316660.6
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr16_+_31483374 4.76 ENST00000394863.3
transforming growth factor beta 1 induced transcript 1
chr19_-_16770915 4.73 ENST00000593459.1
ENST00000358726.6
ENST00000597711.1
ENST00000487416.2
Small integral membrane protein 7; Uncharacterized protein
small integral membrane protein 7
chr1_-_11159887 4.66 ENST00000544779.1
ENST00000304457.7
ENST00000376936.4
exosome component 10
chr12_+_117013656 4.59 ENST00000556529.1
microtubule-associated protein 1 light chain 3 beta 2
chrX_-_15511438 4.55 ENST00000380420.5
pirin (iron-binding nuclear protein)
chr4_+_113558612 4.54 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr6_-_131291572 4.54 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr2_+_201754135 4.54 ENST00000409357.1
ENST00000409129.2
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr19_-_8070474 4.53 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1
chr19_-_291133 4.53 ENST00000327790.3
phosphatidic acid phosphatase type 2C
chr3_-_149093499 4.49 ENST00000472441.1
transmembrane 4 L six family member 1
chr1_+_214776516 4.48 ENST00000366955.3
centromere protein F, 350/400kDa
chr11_+_118955583 4.47 ENST00000278715.3
ENST00000536813.1
ENST00000537841.1
ENST00000542729.1
ENST00000546302.1
ENST00000442944.2
ENST00000544387.1
ENST00000543090.1
hydroxymethylbilane synthase
chr15_-_85259294 4.39 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr12_+_75874984 4.38 ENST00000550491.1
GLI pathogenesis-related 1
chr5_-_122372354 4.38 ENST00000306442.4
peptidylprolyl isomerase C (cyclophilin C)
chr8_-_80942467 4.37 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
mitochondrial ribosomal protein S28
chr2_-_1748214 4.36 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
peroxidasin homolog (Drosophila)
chr14_+_96722539 4.36 ENST00000553356.1
bradykinin receptor B1
chr15_-_72523454 4.31 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
pyruvate kinase, muscle
chr19_+_36705504 4.31 ENST00000456324.1
zinc finger protein 146
chr11_-_62439012 4.30 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
chromosome 11 open reading frame 48
chr14_+_35761580 4.29 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_-_50154921 4.27 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr10_+_35416223 4.26 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr1_+_93297622 4.18 ENST00000315741.5
ribosomal protein L5
chr11_+_58910295 4.16 ENST00000420244.1
family with sequence similarity 111, member A
chr3_+_100428316 4.15 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr9_+_128024067 4.15 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GTPase activating protein and VPS9 domains 1
chrX_-_109590174 4.14 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr13_+_29233218 4.12 ENST00000380842.4
proteasome maturation protein
chr10_+_45495898 4.11 ENST00000298299.3
zinc finger protein 22
chr20_+_34129770 4.09 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC and golgi 3
chr10_+_13203543 4.08 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
minichromosome maintenance complex component 10
chr6_-_42185583 4.07 ENST00000053468.3
mitochondrial ribosomal protein S10
chr5_-_81574160 4.04 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
ribosomal protein S23
chr6_+_63921351 4.02 ENST00000370659.1
FK506 binding protein 1C
chr2_+_209130965 4.00 ENST00000392202.3
ENST00000264380.4
ENST00000407449.1
ENST00000308862.6
phosphoinositide kinase, FYVE finger containing
chr1_-_245027833 3.97 ENST00000444376.2
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr12_+_22778009 3.95 ENST00000266517.4
ENST00000335148.3
ethanolamine kinase 1
chr15_-_85259330 3.94 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr6_-_52149475 3.93 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
minichromosome maintenance complex component 3
chr6_+_150070857 3.93 ENST00000544496.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_-_151735937 3.88 ENST00000368829.3
ENST00000368830.3
mitochondrial ribosomal protein L9
chr14_+_35761540 3.87 ENST00000261479.4
proteasome (prosome, macropain) subunit, alpha type, 6
chr3_-_52804872 3.86 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NIMA-related kinase 4
chr12_+_75874580 3.85 ENST00000456650.3
GLI pathogenesis-related 1
chr10_-_71930222 3.82 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1 homolog A (S. cerevisiae)
chr6_+_160211481 3.81 ENST00000367034.4
mitochondrial ribosomal protein L18
chr1_-_245027766 3.78 ENST00000283179.9
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_-_19746236 3.78 ENST00000375144.1
capping protein (actin filament) muscle Z-line, beta
chr6_-_79944336 3.76 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr3_+_100428188 3.75 ENST00000418917.2
ENST00000490574.1
TRK-fused gene
chr1_-_39339777 3.74 ENST00000397572.2
MYC binding protein
chr14_-_45603657 3.73 ENST00000396062.3
FK506 binding protein 3, 25kDa
chr1_-_26232522 3.73 ENST00000399728.1
stathmin 1
chr13_+_25875785 3.73 ENST00000381747.3
nucleoporin like 1
chr3_+_124449213 3.68 ENST00000232607.2
ENST00000536109.1
ENST00000538242.1
ENST00000413078.2
uridine monophosphate synthetase
chr15_-_85259384 3.64 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr2_-_70520539 3.62 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr2_+_27651478 3.61 ENST00000379852.3
nuclear receptor binding protein 1
chr10_+_75757863 3.61 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
vinculin
chr7_-_35077653 3.61 ENST00000310974.4
dpy-19-like 1 (C. elegans)
chr1_+_144173162 3.60 ENST00000356801.6
neuroblastoma breakpoint family, member 8
chr10_-_101825151 3.60 ENST00000441382.1
carboxypeptidase N, polypeptide 1
chr5_+_271733 3.57 ENST00000264933.4
programmed cell death 6
chr16_-_11876408 3.57 ENST00000396516.2
zinc finger CCCH-type containing 7A
chr14_-_75536182 3.51 ENST00000555463.1
acylphosphatase 1, erythrocyte (common) type
chr1_+_21766588 3.50 ENST00000454000.2
ENST00000318220.6
ENST00000318249.5
neuroblastoma breakpoint family, member 3
chr1_+_10490779 3.49 ENST00000477755.1
apoptosis-inducing, TAF9-like domain 1
chr7_+_79764104 3.49 ENST00000351004.3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr12_-_9102549 3.48 ENST00000000412.3
mannose-6-phosphate receptor (cation dependent)
chr15_+_63340553 3.47 ENST00000334895.5
tropomyosin 1 (alpha)
chr6_+_26458171 3.46 ENST00000493173.1
ENST00000541522.1
ENST00000429381.1
ENST00000469185.1
butyrophilin, subfamily 2, member A1
chr17_+_57784997 3.45 ENST00000537567.1
ENST00000539763.1
ENST00000587945.1
ENST00000536180.1
ENST00000589823.2
ENST00000592106.1
ENST00000591315.1
ENST00000545362.1
vacuole membrane protein 1
chr3_+_25831567 3.41 ENST00000280701.3
ENST00000420173.2
3-oxoacyl-ACP synthase, mitochondrial
chr1_-_6453399 3.41 ENST00000608083.1
acyl-CoA thioesterase 7
chr16_-_81040415 3.38 ENST00000564174.1
ENST00000562713.1
ENST00000570195.1
ENST00000565925.1
ENST00000565108.1
ENST00000565650.1
ENST00000486645.1
C-x(9)-C motif containing 2
chr16_-_18801582 3.33 ENST00000565420.1
ribosomal protein S15a
chr15_+_49170083 3.30 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr6_+_26458152 3.30 ENST00000312541.5
butyrophilin, subfamily 2, member A1
chr12_+_22778116 3.28 ENST00000538218.1
ethanolamine kinase 1
chr17_-_78120936 3.28 ENST00000576547.1
ENST00000269349.3
eukaryotic translation initiation factor 4A3
chr11_-_89956227 3.25 ENST00000457199.2
ENST00000530765.1
cysteine and histidine-rich domain (CHORD) containing 1
chr4_+_79472673 3.23 ENST00000264908.6
annexin A3
chr8_-_42065075 3.20 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
plasminogen activator, tissue
chr17_+_79968655 3.20 ENST00000583744.1
alveolar soft part sarcoma chromosome region, candidate 1
chr8_-_42065187 3.16 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
plasminogen activator, tissue
chr20_+_1099233 3.16 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr1_+_158979686 3.16 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr2_+_109237717 3.12 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr11_+_65627865 3.11 ENST00000308110.4
MUS81 structure-specific endonuclease subunit
chr1_-_77685084 3.11 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
phosphatidylinositol glycan anchor biosynthesis, class K
chr1_-_89458287 3.10 ENST00000370485.2
cysteine conjugate-beta lyase 2
chr19_+_36630855 3.10 ENST00000589146.1
calpain, small subunit 1
chr3_-_165555200 3.09 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr16_-_18801643 3.06 ENST00000322989.4
ENST00000563390.1
ribosomal protein S15a
chr10_+_76969909 3.05 ENST00000298468.5
ENST00000543351.1
voltage-dependent anion channel 2
chr17_-_46682321 3.05 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr17_-_60142609 3.02 ENST00000397786.2
mediator complex subunit 13
chr15_-_80263506 3.01 ENST00000335661.6
BCL2-related protein A1
chr1_+_158979680 2.99 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr20_+_814377 2.99 ENST00000304189.2
ENST00000381939.1
family with sequence similarity 110, member A
chr15_-_85259360 2.97 ENST00000559729.1
SEC11 homolog A (S. cerevisiae)
chr11_-_33774944 2.96 ENST00000532057.1
ENST00000531080.1
F-box protein 3
chr17_-_73043046 2.94 ENST00000301587.4
ENST00000344546.4
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
chr6_+_52535878 2.88 ENST00000211314.4
transmembrane protein 14A
chr1_-_169337176 2.87 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.9 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
4.3 17.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
4.0 31.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
3.8 15.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
3.5 10.5 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
3.0 5.9 GO:0071029 nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
2.9 8.6 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
2.8 11.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
2.7 8.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
2.6 7.7 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
2.4 12.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
2.2 13.1 GO:0051661 maintenance of centrosome location(GO:0051661)
2.1 6.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
2.1 8.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
2.0 5.9 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
1.9 5.6 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
1.5 5.9 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
1.5 7.3 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.4 13.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.4 4.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.3 3.8 GO:0035928 rRNA import into mitochondrion(GO:0035928)
1.3 1.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
1.2 3.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.2 3.6 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.1 7.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.1 3.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
1.1 14.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
1.1 3.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.1 12.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.0 4.2 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.0 3.1 GO:0014016 neuroblast differentiation(GO:0014016)
1.0 3.0 GO:0035978 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
1.0 6.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.0 9.0 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
1.0 5.9 GO:0006344 maintenance of chromatin silencing(GO:0006344)
1.0 9.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
1.0 7.8 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.9 9.9 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.9 5.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.9 3.6 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.9 2.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.9 3.5 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.8 2.5 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.8 3.8 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.7 3.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.7 2.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.7 2.2 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.7 3.6 GO:0030070 insulin processing(GO:0030070)
0.7 4.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.7 5.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.7 2.8 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.7 19.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.7 4.8 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.7 6.1 GO:0030091 protein repair(GO:0030091)
0.7 2.0 GO:1990523 bone regeneration(GO:1990523)
0.7 9.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.6 10.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.6 9.5 GO:0048311 mitochondrion distribution(GO:0048311)
0.6 8.0 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.6 4.9 GO:0032790 ribosome disassembly(GO:0032790)
0.6 3.6 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.6 4.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.6 1.2 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.6 10.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.6 18.1 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.6 1.7 GO:0048382 mesendoderm development(GO:0048382)
0.6 12.4 GO:0006465 signal peptide processing(GO:0006465)
0.6 8.4 GO:0016180 snRNA processing(GO:0016180)
0.6 5.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 19.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.5 1.5 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.5 4.5 GO:0051382 kinetochore assembly(GO:0051382)
0.5 8.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.5 2.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.4 3.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 2.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.4 1.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4 22.3 GO:0043486 histone exchange(GO:0043486)
0.4 10.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.4 3.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 7.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 1.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.4 1.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.4 17.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.4 1.6 GO:0046209 nitric oxide biosynthetic process(GO:0006809) nitric oxide metabolic process(GO:0046209)
0.4 2.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.4 18.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.4 3.9 GO:0001302 replicative cell aging(GO:0001302)
0.4 2.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.4 1.5 GO:0030242 pexophagy(GO:0030242)
0.4 1.5 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.4 2.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 1.1 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.3 3.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.3 11.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 4.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 11.0 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.3 1.9 GO:0035803 egg coat formation(GO:0035803)
0.3 6.7 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.3 1.9 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.3 11.1 GO:0045143 homologous chromosome segregation(GO:0045143)
0.3 4.5 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.3 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 0.8 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.3 4.3 GO:0043248 proteasome assembly(GO:0043248)
0.3 2.9 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.3 12.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 2.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 4.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 6.6 GO:0031639 plasminogen activation(GO:0031639)
0.2 0.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 12.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.2 1.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 7.5 GO:0006270 DNA replication initiation(GO:0006270)
0.2 4.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 4.0 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 2.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 2.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 9.5 GO:0006301 postreplication repair(GO:0006301)
0.2 0.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 11.0 GO:0030224 monocyte differentiation(GO:0030224)
0.2 2.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 1.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 3.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.8 GO:0071233 cellular response to leucine(GO:0071233)
0.2 17.7 GO:0007052 mitotic spindle organization(GO:0007052)
0.2 2.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.2 6.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.2 1.6 GO:0051964 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.2 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.2 12.3 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 1.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.2 10.7 GO:0006342 chromatin silencing(GO:0006342)
0.2 5.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 12.4 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.2 6.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.2 2.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 0.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.6 GO:0015808 L-alanine transport(GO:0015808)
0.2 0.9 GO:0060501 negative regulation of keratinocyte differentiation(GO:0045617) positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 5.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 4.0 GO:0032288 myelin assembly(GO:0032288)
0.1 5.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 3.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.8 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.5 GO:2000232 regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232)
0.1 1.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 6.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 8.3 GO:0090114 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.1 3.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 2.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 1.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.7 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.3 GO:0045116 protein neddylation(GO:0045116)
0.1 2.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 1.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.9 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 9.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 2.5 GO:0018126 protein hydroxylation(GO:0018126)
0.1 3.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 1.4 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1 3.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.7 GO:0032808 lacrimal gland development(GO:0032808)
0.1 2.0 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 3.8 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 1.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.0 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 1.8 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 4.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.5 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 5.0 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.4 GO:0032259 methylation(GO:0032259)
0.1 3.1 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 2.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 1.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.0 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:0031929 TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
0.1 3.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 4.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 2.6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 3.2 GO:0021766 hippocampus development(GO:0021766)
0.0 3.8 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 3.2 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 1.9 GO:0048858 cell projection morphogenesis(GO:0048858)
0.0 0.9 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.4 GO:0003018 vascular process in circulatory system(GO:0003018) regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.0 1.4 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 3.2 GO:0042476 odontogenesis(GO:0042476)
0.0 0.8 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.5 GO:0006874 cellular calcium ion homeostasis(GO:0006874) calcium ion homeostasis(GO:0055074) cellular divalent inorganic cation homeostasis(GO:0072503)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 3.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.1 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.5 GO:0007369 gastrulation(GO:0007369)
0.0 1.5 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.6 GO:0030001 metal ion transport(GO:0030001)
0.0 0.3 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 1.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 1.0 GO:0034101 erythrocyte homeostasis(GO:0034101)
0.0 1.3 GO:0022617 extracellular matrix disassembly(GO:0022617)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.5 GO:0031262 Ndc80 complex(GO:0031262)
2.6 7.8 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
2.3 6.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
2.3 16.2 GO:0036449 microtubule minus-end(GO:0036449)
2.2 6.7 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
2.1 14.9 GO:0005787 signal peptidase complex(GO:0005787)
2.1 23.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.8 7.3 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
1.8 9.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.8 10.6 GO:0001740 Barr body(GO:0001740)
1.7 8.6 GO:0097149 centralspindlin complex(GO:0097149)
1.7 13.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.6 19.7 GO:0043203 axon hillock(GO:0043203)
1.6 7.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.5 5.9 GO:0044611 nuclear pore inner ring(GO:0044611)
1.3 13.4 GO:1990023 mitotic spindle midzone(GO:1990023)
1.3 6.5 GO:0001940 male pronucleus(GO:0001940)
1.2 6.2 GO:0071986 Ragulator complex(GO:0071986)
1.2 5.9 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
1.0 3.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
1.0 4.9 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.9 8.4 GO:0032039 integrator complex(GO:0032039)
0.9 13.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.9 4.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.8 13.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.8 7.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.8 9.1 GO:0042555 MCM complex(GO:0042555)
0.7 2.2 GO:0070939 Dsl1p complex(GO:0070939)
0.7 8.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.7 12.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.6 17.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.6 11.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6 4.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 2.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5 3.8 GO:0071203 WASH complex(GO:0071203)
0.5 12.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.5 4.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 4.1 GO:0031298 replication fork protection complex(GO:0031298)
0.5 9.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 1.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.5 17.1 GO:0090544 BAF-type complex(GO:0090544)
0.4 3.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 2.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.4 1.3 GO:1903349 omegasome membrane(GO:1903349)
0.4 8.2 GO:0000812 Swr1 complex(GO:0000812)
0.4 13.5 GO:0000421 autophagosome membrane(GO:0000421)
0.3 4.5 GO:0008091 spectrin(GO:0008091)
0.3 8.6 GO:0031143 pseudopodium(GO:0031143)
0.3 8.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 2.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 3.6 GO:0005916 fascia adherens(GO:0005916)
0.3 2.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.3 3.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 3.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 8.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.3 19.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 2.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 2.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 17.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 3.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.1 GO:0033503 HULC complex(GO:0033503)
0.2 1.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 4.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 3.5 GO:0032059 bleb(GO:0032059)
0.2 3.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 4.3 GO:0005839 proteasome core complex(GO:0005839)
0.2 7.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 1.0 GO:0033263 CORVET complex(GO:0033263)
0.2 3.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 2.0 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 9.8 GO:0005876 spindle microtubule(GO:0005876)
0.2 12.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 6.3 GO:0005657 replication fork(GO:0005657)
0.2 1.0 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 2.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.4 GO:0034709 methylosome(GO:0034709)
0.1 1.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 11.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 31.1 GO:0005840 ribosome(GO:0005840)
0.1 0.4 GO:0031090 organelle membrane(GO:0031090)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 7.4 GO:0015030 Cajal body(GO:0015030)
0.1 2.8 GO:0046930 pore complex(GO:0046930)
0.1 2.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.2 GO:0031588 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.7 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.0 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.8 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 61.9 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.0 GO:0099738 cell cortex region(GO:0099738)
0.1 6.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 2.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 24.2 GO:1990904 ribonucleoprotein complex(GO:1990904)
0.0 4.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 5.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0005813 centrosome(GO:0005813)
0.0 2.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 20.3 GO:0005730 nucleolus(GO:0005730)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 6.2 GO:0005874 microtubule(GO:0005874)
0.0 4.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.6 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
3.6 10.8 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
3.5 10.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
2.8 30.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
2.6 7.8 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.0 6.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.9 13.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
1.9 5.6 GO:0004170 dUTP diphosphatase activity(GO:0004170)
1.8 5.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.8 3.5 GO:0003998 acylphosphatase activity(GO:0003998)
1.7 9.9 GO:1990254 keratin filament binding(GO:1990254)
1.6 4.7 GO:0004947 bradykinin receptor activity(GO:0004947)
1.4 8.6 GO:0015057 thrombin receptor activity(GO:0015057)
1.4 5.4 GO:0043515 kinetochore binding(GO:0043515)
1.1 12.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.1 10.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.1 4.3 GO:0004743 pyruvate kinase activity(GO:0004743)
1.0 3.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.9 5.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.9 41.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.9 8.0 GO:0035174 histone serine kinase activity(GO:0035174)
0.9 8.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.9 4.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.9 8.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.8 3.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.8 3.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.7 8.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.7 2.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.7 4.0 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.6 2.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.6 26.7 GO:0004532 exoribonuclease activity(GO:0004532)
0.6 8.0 GO:0008097 5S rRNA binding(GO:0008097)
0.6 11.6 GO:0070628 proteasome binding(GO:0070628)
0.5 3.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.5 2.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 4.9 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.5 3.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.5 4.8 GO:0048495 Roundabout binding(GO:0048495)
0.5 7.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.5 7.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 17.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.5 4.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.5 9.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.5 4.5 GO:0042731 PH domain binding(GO:0042731)
0.4 18.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.4 11.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 7.8 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.4 6.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 4.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 9.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 8.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 7.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 1.1 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 4.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 3.1 GO:0015288 porin activity(GO:0015288)
0.3 14.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 1.9 GO:0030492 hemoglobin binding(GO:0030492)
0.3 9.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 4.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 3.6 GO:0089720 caspase binding(GO:0089720)
0.3 1.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 2.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.7 GO:0098821 BMP receptor activity(GO:0098821)
0.3 2.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 8.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 3.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 3.0 GO:0004312 fatty acid synthase activity(GO:0004312)
0.2 4.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 6.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 9.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 3.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.2 7.8 GO:0019956 chemokine binding(GO:0019956)
0.2 4.1 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.9 GO:0032190 acrosin binding(GO:0032190)
0.2 5.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 8.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 3.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 10.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 2.0 GO:0031013 troponin I binding(GO:0031013)
0.2 5.7 GO:0070064 proline-rich region binding(GO:0070064)
0.2 5.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 0.5 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.2 1.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 0.6 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.2 0.8 GO:0070728 leucine binding(GO:0070728)
0.2 3.0 GO:0051400 BH domain binding(GO:0051400)
0.1 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 9.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 3.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 3.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 19.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 3.3 GO:0043531 ADP binding(GO:0043531)
0.1 24.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.2 GO:0008603 cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 3.5 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.7 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 1.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.4 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 10.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.4 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.1 3.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 7.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 6.2 GO:0032947 protein complex scaffold(GO:0032947)
0.1 5.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 10.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 19.8 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 3.7 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) dynein intermediate chain binding(GO:0045505)
0.1 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 3.4 GO:0030145 manganese ion binding(GO:0030145)
0.1 2.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 4.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 7.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 42.1 GO:0003723 RNA binding(GO:0003723)
0.0 4.1 GO:0051015 actin filament binding(GO:0051015)
0.0 3.5 GO:0008201 heparin binding(GO:0008201)
0.0 7.5 GO:0003924 GTPase activity(GO:0003924)
0.0 1.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0019239 deaminase activity(GO:0019239)
0.0 0.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 31.3 PID AURORA A PATHWAY Aurora A signaling
0.5 3.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.4 22.3 PID AURORA B PATHWAY Aurora B signaling
0.3 8.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 7.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 18.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 10.2 ST GA12 PATHWAY G alpha 12 Pathway
0.2 2.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 3.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 11.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 9.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 7.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 6.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 5.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 7.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 12.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 7.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.0 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.9 PID E2F PATHWAY E2F transcription factor network
0.0 2.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 7.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 18.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.2 13.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.1 18.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.7 4.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.7 9.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.6 9.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.6 10.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.5 5.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.5 11.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.5 29.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.4 11.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 11.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 7.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.4 11.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.4 17.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 24.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 41.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 9.1 REACTOME KINESINS Genes involved in Kinesins
0.3 7.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 23.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 9.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 2.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.3 7.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 9.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 4.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 8.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 5.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 9.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 3.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 4.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 4.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 4.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 5.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 4.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 24.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 10.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 4.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 3.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 7.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 4.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 6.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 7.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.4 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 7.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 11.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 3.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 4.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC