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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for IKZF2

Z-value: 0.78

Motif logo

Transcription factors associated with IKZF2

Gene Symbol Gene ID Gene Info
ENSG00000030419.12 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2hg19_v2_chr2_-_214014959_2140150580.111.2e-01Click!

Activity profile of IKZF2 motif

Sorted Z-values of IKZF2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_189839046 9.08 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr5_-_42811986 8.26 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr5_-_42812143 7.86 ENST00000514985.1
selenoprotein P, plasma, 1
chr1_-_57045228 7.24 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr12_-_91573316 6.87 ENST00000393155.1
decorin
chr12_-_91573249 6.86 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr12_-_91573132 6.82 ENST00000550563.1
ENST00000546370.1
decorin
chrX_+_73164149 5.77 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX transcript, XIST activator (non-protein coding)
chrX_+_133733457 5.57 ENST00000440614.1
RP11-308B5.2
chr18_-_53070913 5.48 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr4_+_158141806 5.48 ENST00000393815.2
glutamate receptor, ionotropic, AMPA 2
chr4_+_158141843 5.14 ENST00000509417.1
ENST00000296526.7
glutamate receptor, ionotropic, AMPA 2
chr4_+_158141899 5.12 ENST00000264426.9
ENST00000506284.1
glutamate receptor, ionotropic, AMPA 2
chr3_-_18480260 5.10 ENST00000454909.2
SATB homeobox 1
chr8_-_19459993 4.68 ENST00000454498.2
ENST00000520003.1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr6_-_152639479 4.61 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr3_-_18466026 4.54 ENST00000417717.2
SATB homeobox 1
chr8_+_80523962 4.35 ENST00000518491.1
stathmin-like 2
chr8_+_80523321 4.19 ENST00000518111.1
stathmin-like 2
chr4_-_71532339 4.01 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_190044480 3.84 ENST00000374866.3
collagen, type V, alpha 2
chr3_-_114035026 3.73 ENST00000570269.1
RP11-553L6.5
chr17_-_6915646 3.63 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chrX_+_55478538 3.62 ENST00000342972.1
melanoma antigen family H, 1
chr4_-_153303658 3.46 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chrX_+_103031758 3.39 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chrX_+_103031421 3.37 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr12_-_6580094 3.34 ENST00000361716.3
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr3_+_238273 3.02 ENST00000256509.2
cell adhesion molecule L1-like
chr6_+_31637944 2.99 ENST00000375864.4
lymphocyte antigen 6 complex, locus G5B
chr4_-_83765613 2.90 ENST00000503937.1
SEC31 homolog A (S. cerevisiae)
chr18_-_21852143 2.90 ENST00000399443.3
oxysterol binding protein-like 1A
chr5_-_16509101 2.84 ENST00000399793.2
family with sequence similarity 134, member B
chr4_+_39184024 2.67 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WD repeat domain 19
chr2_-_136288113 2.61 ENST00000401392.1
zinc finger, RAN-binding domain containing 3
chr8_-_17942432 2.59 ENST00000381733.4
ENST00000314146.10
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr10_-_98031310 2.58 ENST00000427367.2
ENST00000413476.2
B-cell linker
chr3_+_10068095 2.56 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr10_-_79789291 2.52 ENST00000372371.3
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr2_+_190722119 2.52 ENST00000452382.1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr1_+_168148273 2.48 ENST00000367830.3
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr18_-_53089723 2.47 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chrX_+_135230712 2.46 ENST00000535737.1
four and a half LIM domains 1
chrX_+_80457442 2.44 ENST00000373212.5
SH3 domain binding glutamic acid-rich protein like
chr14_-_106926724 2.43 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr14_-_60337684 2.42 ENST00000267484.5
reticulon 1
chr4_+_26322409 2.42 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
recombination signal binding protein for immunoglobulin kappa J region
chr2_-_127963343 2.40 ENST00000335247.7
cytochrome P450, family 27, subfamily C, polypeptide 1
chr10_-_98031265 2.37 ENST00000224337.5
ENST00000371176.2
B-cell linker
chr1_-_203151933 2.31 ENST00000404436.2
chitinase 3-like 1 (cartilage glycoprotein-39)
chr8_+_26240414 2.31 ENST00000380629.2
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr7_+_138482695 2.30 ENST00000422794.2
ENST00000397602.3
ENST00000442682.2
ENST00000458494.1
ENST00000413208.1
transmembrane protein 213
chr4_+_26322185 2.27 ENST00000361572.6
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_33891362 2.21 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr15_-_34880646 2.20 ENST00000543376.1
golgin A8 family, member A
chr1_+_101185290 2.17 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
vascular cell adhesion molecule 1
chr4_+_124320665 2.16 ENST00000394339.2
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr8_-_82024290 2.15 ENST00000220597.4
phosphoprotein associated with glycosphingolipid microdomains 1
chr4_-_89978299 2.08 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
family with sequence similarity 13, member A
chr4_-_153456153 2.08 ENST00000603548.1
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr14_-_45431091 2.02 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
kelch-like family member 28
chr14_+_45431379 1.97 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
family with sequence similarity 179, member B
chr9_+_2159850 1.96 ENST00000416751.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_158979680 1.95 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr10_+_105036909 1.91 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr1_+_158979686 1.86 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr13_+_58206655 1.84 ENST00000377918.3
protocadherin 17
chr15_-_20193370 1.81 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr6_-_128841503 1.81 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr10_+_48189612 1.81 ENST00000453919.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr20_+_44509857 1.77 ENST00000372523.1
ENST00000372520.1
zinc finger, SWIM-type containing 1
chrX_+_135251783 1.76 ENST00000394153.2
four and a half LIM domains 1
chr11_-_72385437 1.75 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
phosphodiesterase 2A, cGMP-stimulated
chr1_+_104198377 1.73 ENST00000370083.4
amylase, alpha 1A (salivary)
chr9_-_36401155 1.72 ENST00000377885.2
ring finger protein 38
chr6_+_147830063 1.64 ENST00000367474.1
sterile alpha motif domain containing 5
chr8_+_97597148 1.61 ENST00000521590.1
syndecan 2
chr14_-_106552755 1.60 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr3_-_183273477 1.60 ENST00000341319.3
kelch-like family member 6
chr13_-_38172863 1.59 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr16_+_28763108 1.58 ENST00000357796.3
ENST00000550983.1
nuclear pore complex interacting protein family, member B9
chr1_+_158979792 1.58 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr4_+_176986978 1.55 ENST00000508596.1
ENST00000393643.2
WD repeat domain 17
chr4_-_153274078 1.54 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr14_-_107114267 1.52 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr6_+_32605195 1.52 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chrX_+_135252050 1.50 ENST00000449474.1
ENST00000345434.3
four and a half LIM domains 1
chrX_-_43741594 1.50 ENST00000536181.1
ENST00000378069.4
monoamine oxidase B
chr8_+_85095553 1.49 ENST00000521268.1
RALY RNA binding protein-like
chrX_+_45364633 1.48 ENST00000435394.1
ENST00000609127.1
RP11-245M24.1
chr4_-_74486347 1.47 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_158733692 1.47 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chrX_-_102941596 1.46 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
mortality factor 4 like 2
chr10_-_47239738 1.45 ENST00000413193.2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr6_+_43149903 1.42 ENST00000252050.4
ENST00000354495.3
ENST00000372647.2
cullin 9
chr9_+_124062071 1.41 ENST00000373818.4
gelsolin
chr2_+_102508955 1.39 ENST00000414004.2
FLJ20373
chr5_-_111091948 1.39 ENST00000447165.2
neuronal regeneration related protein
chr4_-_74486217 1.33 ENST00000335049.5
ENST00000307439.5
Ras association (RalGDS/AF-6) domain family member 6
chr2_-_174830430 1.30 ENST00000310015.6
ENST00000455789.2
Sp3 transcription factor
chr10_-_112678976 1.30 ENST00000448814.1
BBSome interacting protein 1
chr9_-_91793675 1.30 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr19_+_48773337 1.28 ENST00000595607.1
zinc finger protein 114
chr9_-_139334247 1.28 ENST00000371712.3
inositol polyphosphate-5-phosphatase, 72 kDa
chr8_+_9046503 1.23 ENST00000512942.2
RP11-10A14.5
chr8_+_85095769 1.23 ENST00000518566.1
RALY RNA binding protein-like
chr16_-_28374829 1.20 ENST00000532254.1
nuclear pore complex interacting protein family, member B6
chr15_+_43885252 1.19 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr20_+_4702548 1.19 ENST00000305817.2
prion protein 2 (dublet)
chr13_-_46756351 1.18 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr15_+_43985084 1.17 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr15_+_43985725 1.16 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr2_-_225434538 1.13 ENST00000409096.1
cullin 3
chr12_+_62860581 1.11 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
MON2 homolog (S. cerevisiae)
chr16_+_89334512 1.11 ENST00000602042.1
AC137932.1
chrX_+_100805496 1.10 ENST00000372829.3
armadillo repeat containing, X-linked 1
chr17_+_46537697 1.10 ENST00000579972.1
RP11-433M22.2
chr13_+_20532848 1.10 ENST00000382874.2
zinc finger, MYM-type 2
chr6_+_32605134 1.08 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr8_-_9760839 1.06 ENST00000519461.1
ENST00000517675.1
long intergenic non-protein coding RNA 599
chr1_-_169599314 1.05 ENST00000367786.2
ENST00000458599.2
ENST00000367795.2
ENST00000263686.6
selectin P (granule membrane protein 140kDa, antigen CD62)
chr11_-_108093329 1.04 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr1_-_169599353 1.04 ENST00000367793.2
ENST00000367794.2
ENST00000367792.2
ENST00000367791.2
ENST00000367788.2
selectin P (granule membrane protein 140kDa, antigen CD62)
chrX_-_133119476 1.03 ENST00000543339.1
glypican 3
chr8_+_39770803 1.02 ENST00000518237.1
indoleamine 2,3-dioxygenase 1
chr14_+_64970662 1.02 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chrX_+_100663243 1.02 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr11_+_11863579 1.02 ENST00000399455.2
ubiquitin specific peptidase 47
chr17_+_7792101 1.01 ENST00000358181.4
ENST00000330494.7
chromodomain helicase DNA binding protein 3
chr18_+_43914159 1.00 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
ring finger protein 165
chr1_-_216978709 0.98 ENST00000360012.3
estrogen-related receptor gamma
chr14_-_106668095 0.98 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr10_+_112679301 0.98 ENST00000265277.5
ENST00000369452.4
soc-2 suppressor of clear homolog (C. elegans)
chr12_+_26348246 0.95 ENST00000422622.2
sarcospan
chr14_-_90798418 0.95 ENST00000354366.3
NRDE-2, necessary for RNA interference, domain containing
chr14_+_56078695 0.95 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr2_+_98330009 0.94 ENST00000264972.5
zeta-chain (TCR) associated protein kinase 70kDa
chr2_+_27301435 0.94 ENST00000380320.4
elastin microfibril interfacer 1
chr10_-_116444371 0.92 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr2_-_24583168 0.91 ENST00000361999.3
intersectin 2
chr6_-_143266297 0.91 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr16_-_33647696 0.90 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein
chr11_+_71903169 0.90 ENST00000393676.3
folate receptor 1 (adult)
chr14_-_106610852 0.89 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr12_-_104443890 0.88 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
glycosyltransferase 8 domain containing 2
chr14_-_64970494 0.88 ENST00000608382.1
zinc finger and BTB domain containing 25
chr12_+_26348429 0.86 ENST00000242729.2
sarcospan
chr10_-_79398250 0.86 ENST00000286627.5
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_-_43709703 0.85 ENST00000599391.1
ENST00000244295.9
pregnancy specific beta-1-glycoprotein 4
chr1_+_40627038 0.84 ENST00000372771.4
rearranged L-myc fusion
chrX_+_135251835 0.83 ENST00000456445.1
four and a half LIM domains 1
chr12_-_118796910 0.82 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr14_+_32546274 0.82 ENST00000396582.2
Rho GTPase activating protein 5
chr13_+_20532900 0.80 ENST00000382871.2
zinc finger, MYM-type 2
chr20_-_45981138 0.80 ENST00000446994.2
zinc finger, MYND-type containing 8
chr4_-_77997126 0.79 ENST00000537948.1
ENST00000507788.1
ENST00000237654.4
cyclin I
chr2_+_33661382 0.78 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chrX_-_33229636 0.77 ENST00000357033.4
dystrophin
chr21_-_28338732 0.77 ENST00000284987.5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_+_136289030 0.76 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3H domain containing 1
chr9_+_706842 0.75 ENST00000382293.3
KN motif and ankyrin repeat domains 1
chr8_-_18541603 0.75 ENST00000428502.2
pleckstrin and Sec7 domain containing 3
chr12_+_26348582 0.74 ENST00000535504.1
sarcospan
chr17_+_27047244 0.74 ENST00000394938.4
ENST00000394935.3
ENST00000355731.4
ribosomal protein L23a
chr5_-_34043310 0.72 ENST00000231338.7
C1q and tumor necrosis factor related protein 3
chr19_+_30863271 0.71 ENST00000355537.3
zinc finger protein 536
chr17_+_55055466 0.70 ENST00000262288.3
ENST00000572710.1
ENST00000575395.1
serine carboxypeptidase 1
chr1_+_24019099 0.70 ENST00000443624.1
ENST00000458455.1
ribosomal protein L11
chr2_+_48796120 0.68 ENST00000394754.1
STON1-GTF2A1L readthrough
chr4_+_68424434 0.67 ENST00000265404.2
ENST00000396225.1
signal transducing adaptor family member 1
chr4_+_144434584 0.67 ENST00000283131.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr3_-_16646949 0.67 ENST00000399444.2
deleted in azoospermia-like
chr7_+_73442487 0.67 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
elastin
chr2_-_216257849 0.65 ENST00000456923.1
fibronectin 1
chr2_+_187350883 0.65 ENST00000337859.6
zinc finger CCCH-type containing 15
chr13_-_99959641 0.65 ENST00000376414.4
G protein-coupled receptor 183
chr1_+_9711781 0.64 ENST00000536656.1
ENST00000377346.4
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr9_+_92219919 0.64 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr12_+_122459757 0.63 ENST00000261822.4
B-cell CLL/lymphoma 7A
chr12_-_26278030 0.63 ENST00000242728.4
basic helix-loop-helix family, member e41
chr5_+_32710736 0.62 ENST00000415685.2
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr12_-_80328949 0.62 ENST00000450142.2
protein phosphatase 1, regulatory subunit 12A
chr20_+_57209828 0.62 ENST00000598340.1
HCG1785561; MGC4294 protein; Uncharacterized protein
chr6_-_131384373 0.62 ENST00000392427.3
ENST00000525271.1
ENST00000527411.1
erythrocyte membrane protein band 4.1-like 2
chr9_-_6015607 0.60 ENST00000259569.5
RAN binding protein 6
chr6_+_32944119 0.59 ENST00000606059.1
bromodomain containing 2
chr6_-_131384412 0.58 ENST00000445890.2
ENST00000368128.2
ENST00000337057.3
erythrocyte membrane protein band 4.1-like 2
chr1_+_111682058 0.58 ENST00000545121.1
choline/ethanolamine phosphotransferase 1
chr7_-_74221288 0.57 ENST00000451013.2
GTF2I repeat domain containing 2
chr12_-_118797475 0.57 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr7_+_73442457 0.55 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
elastin
chr19_-_43421989 0.55 ENST00000292125.2
ENST00000187910.2
pregnancy specific beta-1-glycoprotein 6
chrX_+_48660287 0.54 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
histone deacetylase 6
chr8_-_101964231 0.53 ENST00000521309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr4_-_120243545 0.53 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr5_+_32711419 0.52 ENST00000265074.8
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr6_-_131384347 0.52 ENST00000530481.1
erythrocyte membrane protein band 4.1-like 2
chr4_-_109088940 0.52 ENST00000438313.2
lymphoid enhancer-binding factor 1
chrX_+_21874105 0.51 ENST00000429584.2
YY2 transcription factor
chr19_-_43269809 0.51 ENST00000406636.3
ENST00000404209.4
ENST00000306511.4
pregnancy specific beta-1-glycoprotein 8

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.7 20.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.6 4.7 GO:1901297 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
1.4 7.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.2 4.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
1.1 9.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.0 3.8 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.9 2.7 GO:0061055 myotome development(GO:0061055)
0.7 2.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.6 9.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.6 1.8 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.5 1.6 GO:1990523 bone regeneration(GO:1990523)
0.5 4.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.4 2.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 6.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.4 2.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.4 2.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.3 15.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 0.9 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.3 0.9 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.3 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.3 1.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.3 1.4 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.3 1.8 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.3 1.0 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.3 1.0 GO:0036269 swimming behavior(GO:0036269)
0.3 1.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.3 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 2.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 1.6 GO:0008218 bioluminescence(GO:0008218)
0.2 0.7 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.2 1.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.2 0.7 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.6 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.2 1.5 GO:0010269 response to selenium ion(GO:0010269)
0.2 0.6 GO:0060374 mast cell differentiation(GO:0060374)
0.2 2.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 0.5 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.2 0.7 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 3.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 2.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.2 1.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.2 0.9 GO:0043366 beta selection(GO:0043366)
0.1 2.4 GO:0042574 retinal metabolic process(GO:0042574)
0.1 2.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.4 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 1.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.8 GO:1902952 regulation of postsynaptic density protein 95 clustering(GO:1902897) positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.4 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 2.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.6 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 1.8 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 6.6 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.1 2.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 7.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 5.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.5 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 1.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.7 GO:0007135 meiosis II(GO:0007135)
0.1 1.6 GO:0002467 germinal center formation(GO:0002467)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 2.6 GO:0035640 exploration behavior(GO:0035640)
0.1 0.9 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 1.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0015074 DNA integration(GO:0015074)
0.1 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 1.0 GO:0090168 Golgi reassembly(GO:0090168)
0.1 2.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.0 2.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 2.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.7 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:1990936 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.7 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 4.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.7 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.6 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 7.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 2.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0097484 dendrite extension(GO:0097484)
0.0 0.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.5 GO:0034694 response to prostaglandin(GO:0034694)
0.0 1.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 1.7 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.0 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.5 20.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.3 3.8 GO:0005588 collagen type V trimer(GO:0005588)
1.0 7.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.0 9.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.9 4.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.7 2.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4 2.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 4.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 2.5 GO:0032389 MutLalpha complex(GO:0032389)
0.3 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.2 8.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 1.6 GO:0034464 BBSome(GO:0034464)
0.2 1.7 GO:0071953 elastic fiber(GO:0071953)
0.2 7.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 1.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.9 GO:0005883 neurofilament(GO:0005883)
0.1 2.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.1 GO:0005827 polar microtubule(GO:0005827)
0.1 2.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.7 GO:0008091 spectrin(GO:0008091)
0.1 3.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.9 GO:0043596 nuclear replication fork(GO:0043596)
0.1 1.4 GO:0030478 actin cap(GO:0030478)
0.1 3.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.5 GO:1990130 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 3.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.5 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 8.2 GO:0030426 growth cone(GO:0030426)
0.0 3.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 1.4 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 5.1 GO:0043209 myelin sheath(GO:0043209)
0.0 3.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.5 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.5 GO:0005929 cilium(GO:0005929)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
1.3 15.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.9 7.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.7 2.1 GO:0042806 fucose binding(GO:0042806)
0.7 9.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 2.6 GO:0017040 ceramidase activity(GO:0017040)
0.6 8.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 2.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.6 6.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 3.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 1.7 GO:0016160 amylase activity(GO:0016160)
0.4 4.7 GO:0000150 recombinase activity(GO:0000150)
0.4 7.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 1.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.3 0.9 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.3 1.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 21.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.1 GO:0031208 POZ domain binding(GO:0031208)
0.3 2.6 GO:0036310 annealing helicase activity(GO:0036310)
0.3 1.0 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3 1.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 6.9 GO:0005521 lamin binding(GO:0005521)
0.2 0.9 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 2.3 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.2 1.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 2.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.4 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.7 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 1.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 1.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 7.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 11.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 2.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 3.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 2.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 5.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 11.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 3.0 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 3.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 3.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 19.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 17.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 12.9 NABA COLLAGENS Genes encoding collagen proteins
0.2 2.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 7.1 PID MYC PATHWAY C-MYC pathway
0.1 4.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 8.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 8.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.6 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 3.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 3.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.7 PID FGF PATHWAY FGF signaling pathway
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 4.4 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 0.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8 25.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.7 15.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4 4.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 7.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 12.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 5.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 4.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 1.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 5.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 7.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 10.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 3.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 4.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 2.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription