averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
IRF2 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000168310.6	interferon regulatory factor 2
STAT2 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000170581.9	signal transducer and activator of transcription 2
IRF8 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000140968.6	interferon regulatory factor 8
IRF1 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000125347.9	interferon regulatory factor 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
IRF1	hg19_v2_chr5_-_131826457_131826514	0.77	3.1e-44	Click!
IRF2	hg19_v2_chr4_-_185395672_185395734	0.72	1.2e-36	Click!
IRF8	hg19_v2_chr16_+_85942594_85942635	0.56	1.6e-19	Click!
STAT2	hg19_v2_chr12_-_56753858_56753930	0.02	8.1e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_+_32821924 Show fit	199.84	ENST00000374859.2 ENST00000453265.2	PSMB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 9
chr1_+_948803 Show fit	165.30	ENST00000379389.4	ISG15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ISG15 ubiquitin-like modifier
chr16_-_67970990 Show fit	147.63	ENST00000358514.4	PSMB10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 10
chr11_-_615942 Show fit	126.93	ENST00000397562.3 ENST00000330243.5 ENST00000397570.1 ENST00000397574.2	IRF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon regulatory factor 7
chr6_-_33282163 Show fit	109.81	ENST00000434618.2 ENST00000456592.2	TAPBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAP binding protein (tapasin)
chr21_+_42733870 Show fit	106.90	ENST00000330714.3 ENST00000436410.1 ENST00000435611.1	MX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myxovirus (influenza virus) resistance 2 (mouse)
chr6_+_32811885 Show fit	105.61	ENST00000458296.1 ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1	TAPSAR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit PSMB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9
chr6_-_32811771 Show fit	104.75	ENST00000395339.3 ENST00000374882.3	PSMB8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 8
chr19_-_17516449 Show fit	98.27	ENST00000252593.6	BST2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	bone marrow stromal cell antigen 2
chr1_+_158979792 Show fit	95.71	ENST00000359709.3 ENST00000430894.2	IFI16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon, gamma-inducible protein 16
chr1_+_158979680 Show fit	92.83	ENST00000368131.4 ENST00000340979.6	IFI16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon, gamma-inducible protein 16
chr1_+_158979686 Show fit	92.43	ENST00000368132.3 ENST00000295809.7	IFI16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon, gamma-inducible protein 16
chr11_-_615570 Show fit	89.81	ENST00000525445.1 ENST00000348655.6 ENST00000397566.1	IRF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon regulatory factor 7
chr19_+_1077393 Show fit	89.17	ENST00000590577.1	HMHA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histocompatibility (minor) HA-1
chr1_+_174843548 Show fit	87.50	ENST00000478442.1 ENST00000465412.1	RABGAP1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB GTPase activating protein 1-like
chr2_-_231084820 Show fit	87.29	ENST00000258382.5 ENST00000338556.3	SP110 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SP110 nuclear body protein
chr7_+_74188309 Show fit	85.50	ENST00000289473.4 ENST00000433458.1	NCF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neutrophil cytosolic factor 1
chr6_-_32821599 Show fit	82.69	ENST00000354258.4	TAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr21_+_42792442 Show fit	77.84	ENST00000398600.2	MX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr10_-_91174215 Show fit	76.32	ENST00000371837.1	LIPA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lipase A, lysosomal acid, cholesterol esterase
chr1_+_79086088 Show fit	74.45	ENST00000370751.5 ENST00000342282.3	IFI44L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon-induced protein 44-like
chr1_+_79115503 Show fit	68.63	ENST00000370747.4 ENST00000438486.1 ENST00000545124.1	IFI44 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon-induced protein 44
chr14_+_58711539 Show fit	67.56	ENST00000216455.4 ENST00000412908.2 ENST00000557508.1	PSMA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 3
chr11_+_5710919 Show fit	65.61	ENST00000379965.3 ENST00000425490.1	TRIM22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 22
chr6_+_26365443 Show fit	65.00	ENST00000527422.1 ENST00000356386.2 ENST00000396934.3 ENST00000377708.2 ENST00000396948.1 ENST00000508906.2	BTN3A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin, subfamily 3, member A2
chr6_+_6588902 Show fit	61.35	ENST00000230568.4	LY86 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte antigen 86
chr6_+_26440700 Show fit	59.85	ENST00000494393.1 ENST00000482451.1 ENST00000244519.2 ENST00000339789.4 ENST00000471353.1 ENST00000361232.3 ENST00000487627.1 ENST00000496719.1 ENST00000490254.1 ENST00000487272.1	BTN3A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin, subfamily 3, member A3
chr2_+_201981527 Show fit	59.52	ENST00000441224.1	CFLAR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CASP8 and FADD-like apoptosis regulator
chr2_-_231084659 Show fit	59.29	ENST00000258381.6 ENST00000358662.4 ENST00000455674.1 ENST00000392048.3	SP110 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SP110 nuclear body protein
chr12_+_25205446 Show fit	58.58	ENST00000557489.1 ENST00000354454.3 ENST00000536173.1	LRMP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphoid-restricted membrane protein
chr2_-_231084617 Show fit	58.00	ENST00000409815.2	SP110 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SP110 nuclear body protein
chr16_-_88851618 Show fit	56.96	ENST00000301015.9	PIEZO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	piezo-type mechanosensitive ion channel component 1
chr12_-_49319265 Show fit	56.70	ENST00000552878.1 ENST00000453172.2	FKBP11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FK506 binding protein 11, 19 kDa
chr12_-_49318715 Show fit	55.78	ENST00000444214.2	FKBP11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FK506 binding protein 11, 19 kDa
chr3_-_49851313 Show fit	55.60	ENST00000333486.3	UBA7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-like modifier activating enzyme 7
chr13_+_50070077 Show fit	55.38	ENST00000378319.3 ENST00000426879.1	PHF11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PHD finger protein 11
chr15_+_45003675 Show fit	54.91	ENST00000558401.1 ENST00000559916.1 ENST00000544417.1	B2M Links Ensembl NCBI GeneCards UniProt NextProt Show fit	beta-2-microglobulin
chr4_+_147096837 Show fit	54.82	ENST00000296581.5 ENST00000502781.1	LSM6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_+_24605361 Show fit	54.82	ENST00000206451.6 ENST00000559123.1	PSME1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr12_+_113416191 Show fit	54.61	ENST00000342315.4 ENST00000392583.2	OAS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr14_+_24605389 Show fit	54.55	ENST00000382708.3 ENST00000561435.1	PSME1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr14_-_100841930 Show fit	53.66	ENST00000555031.1 ENST00000553395.1 ENST00000553545.1 ENST00000344102.5 ENST00000556338.1 ENST00000392882.2 ENST00000553934.1	WARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tryptophanyl-tRNA synthetase
chr11_-_57335280 Show fit	53.58	ENST00000287156.4	UBE2L6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2L 6
chr13_+_50070491 Show fit	53.48	ENST00000496612.1 ENST00000357596.3 ENST00000485919.1 ENST00000442195.1	PHF11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PHD finger protein 11
chr2_-_152146385 Show fit	52.52	ENST00000414946.1 ENST00000243346.5	NMI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	N-myc (and STAT) interactor
chr14_-_100841670 Show fit	51.94	ENST00000557297.1 ENST00000555813.1 ENST00000557135.1 ENST00000556698.1 ENST00000554509.1 ENST00000555410.1	WARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tryptophanyl-tRNA synthetase
chr15_+_89182178 Show fit	51.77	ENST00000559876.1	ISG20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon stimulated exonuclease gene 20kDa
chr1_-_154580616 Show fit	49.69	ENST00000368474.4	ADAR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenosine deaminase, RNA-specific
chr11_-_104905840 Show fit	49.21	ENST00000526568.1 ENST00000393136.4 ENST00000531166.1 ENST00000534497.1 ENST00000527979.1 ENST00000446369.1 ENST00000353247.5 ENST00000528974.1 ENST00000533400.1 ENST00000525825.1 ENST00000436863.3	CASP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	caspase 1, apoptosis-related cysteine peptidase
chr6_-_31324943 Show fit	49.20	ENST00000412585.2 ENST00000434333.1	HLA-B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, B
chr12_+_113344755 Show fit	48.62	ENST00000550883.1	OAS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_191878874 Show fit	48.34	ENST00000392322.3 ENST00000392323.2 ENST00000424722.1 ENST00000361099.3	STAT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducer and activator of transcription 1, 91kDa
chr20_+_388935 Show fit	48.27	ENST00000382181.2 ENST00000400247.3	RBCK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RanBP-type and C3HC4-type zinc finger containing 1
chr11_-_104972158 Show fit	47.92	ENST00000598974.1 ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1	CASP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit CARD16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit CARD17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17
chr19_+_18284477 Show fit	47.48	ENST00000407280.3	IFI30 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon, gamma-inducible protein 30
chr15_+_89181974 Show fit	46.67	ENST00000306072.5	ISG20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon stimulated exonuclease gene 20kDa
chr4_-_185395672 Show fit	46.43	ENST00000393593.3	IRF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon regulatory factor 2
chr8_+_144640477 Show fit	46.15	ENST00000262580.4	GSDMD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	gasdermin D
chr1_+_12227035 Show fit	46.04	ENST00000376259.3 ENST00000536782.1	TNFRSF1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor receptor superfamily, member 1B
chr16_-_31214051 Show fit	45.49	ENST00000350605.4	PYCARD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PYD and CARD domain containing
chr1_-_151319710 Show fit	43.22	ENST00000290524.4 ENST00000437327.1 ENST00000452513.2 ENST00000368870.2 ENST00000452671.2	RFX5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulatory factor X, 5 (influences HLA class II expression)
chr3_-_49142178 Show fit	43.20	ENST00000452739.1 ENST00000414533.1 ENST00000417025.1	QARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaminyl-tRNA synthetase
chrX_+_123095546 Show fit	42.53	ENST00000371157.3 ENST00000371145.3 ENST00000371144.3	STAG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stromal antigen 2
chr3_-_49142504 Show fit	41.70	ENST00000306125.6 ENST00000420147.2	QARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaminyl-tRNA synthetase
chr11_+_63304273 Show fit	40.67	ENST00000439013.2 ENST00000255688.3	RARRES3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoic acid receptor responder (tazarotene induced) 3
chr19_+_10196781 Show fit	38.71	ENST00000253110.11	C19orf66 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 19 open reading frame 66
chr5_-_95158375 Show fit	38.59	ENST00000512469.2 ENST00000379979.4 ENST00000505427.1 ENST00000508780.1	GLRX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaredoxin (thioltransferase)
chr17_+_46908350 Show fit	38.00	ENST00000258947.3 ENST00000509507.1 ENST00000448105.2 ENST00000570513.1 ENST00000509415.1 ENST00000513119.1 ENST00000416445.2 ENST00000508679.1 ENST00000505071.1	CALCOCO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium binding and coiled-coil domain 2
chrX_+_37639264 Show fit	37.66	ENST00000378588.4	CYBB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome b-245, beta polypeptide
chr1_+_179050512 Show fit	34.86	ENST00000367627.3	TOR3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	torsin family 3, member A
chr20_+_388679 Show fit	34.67	ENST00000356286.5 ENST00000475269.1	RBCK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_158801095 Show fit	34.59	ENST00000368141.4	MNDA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myeloid cell nuclear differentiation antigen
chr21_+_42798094 Show fit	34.58	ENST00000398598.3 ENST00000455164.2 ENST00000424365.1	MX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr1_-_89531041 Show fit	34.47	ENST00000370473.4	GBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanylate binding protein 1, interferon-inducible
chr2_-_191878681 Show fit	34.37	ENST00000409465.1	STAT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducer and activator of transcription 1, 91kDa
chr16_+_12058961 Show fit	34.10	ENST00000053243.1	TNFRSF17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor receptor superfamily, member 17
chr2_+_231280908 Show fit	33.74	ENST00000427101.2 ENST00000432979.1	SP100 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SP100 nuclear antigen
chr2_+_120687335 Show fit	33.70	ENST00000544261.1	PTPN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr18_+_3262954 Show fit	32.51	ENST00000584539.1	MYL12B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 12B, regulatory
chr4_+_37892682 Show fit	31.49	ENST00000508802.1 ENST00000261439.4 ENST00000402522.1	TBC1D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr5_-_95158644 Show fit	31.48	ENST00000237858.6	GLRX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaredoxin (thioltransferase)
chr17_+_25958174 Show fit	31.12	ENST00000313648.6 ENST00000577392.1 ENST00000584661.1 ENST00000413914.2	LGALS9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lectin, galactoside-binding, soluble, 9
chr16_+_12059050 Show fit	30.85	ENST00000396495.3	TNFRSF17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor receptor superfamily, member 17
chr15_+_89182156 Show fit	30.09	ENST00000379224.5	ISG20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon stimulated exonuclease gene 20kDa
chr12_+_25205666 Show fit	29.97	ENST00000547044.1	LRMP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphoid-restricted membrane protein
chr6_-_41909191 Show fit	29.60	ENST00000512426.1 ENST00000372987.4	CCND3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D3
chr12_-_10022735 Show fit	28.50	ENST00000228438.2	CLEC2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	C-type lectin domain family 2, member B
chr20_-_5100591 Show fit	28.47	ENST00000379143.5	PCNA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proliferating cell nuclear antigen
chr15_+_78832747 Show fit	28.41	ENST00000560217.1 ENST00000044462.7 ENST00000559082.1 ENST00000559948.1 ENST00000413382.2 ENST00000559146.1 ENST00000558281.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr2_+_201981119 Show fit	28.27	ENST00000395148.2	CFLAR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CASP8 and FADD-like apoptosis regulator
chr12_+_6561190 Show fit	28.10	ENST00000544021.1 ENST00000266556.7	TAPBPL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAP binding protein-like
chr16_+_12059091 Show fit	27.90	ENST00000562385.1	TNFRSF17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor receptor superfamily, member 17
chr6_-_159239257 Show fit	27.88	ENST00000337147.7 ENST00000392177.4	EZR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ezrin
chr12_+_94542459 Show fit	27.80	ENST00000258526.4	PLXNC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	plexin C1
chr5_+_49962495 Show fit	27.73	ENST00000515175.1	PARP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	poly (ADP-ribose) polymerase family, member 8
chr5_+_96212185 Show fit	27.52	ENST00000379904.4	ERAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	endoplasmic reticulum aminopeptidase 2
chr3_+_63898275 Show fit	26.98	ENST00000538065.1	ATXN7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ataxin 7
chr3_-_146262488 Show fit	26.32	ENST00000487389.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr12_+_25205568 Show fit	26.11	ENST00000548766.1 ENST00000556887.1	LRMP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphoid-restricted membrane protein
chr12_+_113344811 Show fit	26.10	ENST00000551241.1 ENST00000553185.1 ENST00000550689.1	OAS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr5_+_96211643 Show fit	26.01	ENST00000437043.3 ENST00000510373.1	ERAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	endoplasmic reticulum aminopeptidase 2
chr9_-_100881466 Show fit	25.97	ENST00000341469.2 ENST00000342043.3 ENST00000375098.3	TRIM14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 14
chr5_-_142783694 Show fit	25.74	ENST00000394466.2	NR3C1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_35452104 Show fit	25.73	ENST00000216774.6 ENST00000546080.1	SRP54 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal recognition particle 54kDa
chr11_-_4414880 Show fit	25.57	ENST00000254436.7 ENST00000543625.1	TRIM21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 21
chr10_+_91087651 Show fit	25.53	ENST00000371818.4	IFIT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon-induced protein with tetratricopeptide repeats 3
chr1_-_111746966 Show fit	25.32	ENST00000369752.5	DENND2D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DENN/MADD domain containing 2D
chr2_+_201994569 Show fit	25.27	ENST00000457277.1	CFLAR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CASP8 and FADD-like apoptosis regulator
chr14_-_24615805 Show fit	25.18	ENST00000560410.1	PSME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_-_67169253 Show fit	25.12	ENST00000527663.1 ENST00000312989.7	PPP1CA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, catalytic subunit, alpha isozyme
chr6_+_37400974 Show fit	24.53	ENST00000455891.1 ENST00000373451.4	CMTR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cap methyltransferase 1
chr3_-_172241250 Show fit	24.39	ENST00000420541.2 ENST00000241261.2	TNFSF10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor (ligand) superfamily, member 10
chr3_-_30936153 Show fit	24.11	ENST00000454381.3 ENST00000282538.5	GADL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate decarboxylase-like 1
chr14_+_24630465 Show fit	23.98	ENST00000557894.1 ENST00000559284.1 ENST00000560275.1	IRF9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon regulatory factor 9
chr3_-_146262365 Show fit	23.86	ENST00000448787.2	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr14_+_35452169 Show fit	23.75	ENST00000555557.1	SRP54 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal recognition particle 54kDa
chr16_+_29831715 Show fit	23.67	ENST00000563915.1 ENST00000357402.5	MVP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major vault protein
chr11_-_60719213 Show fit	23.57	ENST00000227880.3	SLC15A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 15 (oligopeptide transporter), member 3
chr6_+_25963020 Show fit	23.31	ENST00000357085.3	TRIM38 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 38
chr18_+_48405463 Show fit	23.16	ENST00000382927.3	ME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	malic enzyme 2, NAD(+)-dependent, mitochondrial
chr11_+_1874200 Show fit	22.96	ENST00000311604.3	LSP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte-specific protein 1
chr12_-_53594227 Show fit	22.83	ENST00000550743.2	ITGB7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, beta 7
chr3_-_121379739 Show fit	22.76	ENST00000428394.2 ENST00000314583.3	HCLS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hematopoietic cell-specific Lyn substrate 1
chr14_+_73563735 Show fit	22.76	ENST00000532192.1	RBM25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein 25
chr16_-_75681522 Show fit	22.75	ENST00000568378.1 ENST00000568682.1 ENST00000570215.1 ENST00000319410.5 ENST00000302445.3	KARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysyl-tRNA synthetase
chr16_+_29831757 Show fit	22.71	ENST00000452209.2 ENST00000395353.1 ENST00000566066.1 ENST00000563558.1	MVP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major vault protein
chrX_+_37639302 Show fit	22.61	ENST00000545017.1 ENST00000536160.1	CYBB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome b-245, beta polypeptide
chr17_+_6659153 Show fit	22.57	ENST00000441631.1 ENST00000438512.1 ENST00000346752.4 ENST00000361842.3	XAF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	XIAP associated factor 1
chr7_-_138794081 Show fit	22.47	ENST00000464606.1	ZC3HAV1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type, antiviral 1
chr2_+_201994208 Show fit	22.23	ENST00000440180.1	CFLAR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CASP8 and FADD-like apoptosis regulator
chr15_-_80263506 Show fit	21.81	ENST00000335661.6	BCL2A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-related protein A1
chr12_-_31479045 Show fit	21.74	ENST00000539409.1 ENST00000395766.1	FAM60A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 60, member A
chr5_-_149792295 Show fit	21.60	ENST00000518797.1 ENST00000524315.1 ENST00000009530.7 ENST00000377795.3	CD74 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD74 molecule, major histocompatibility complex, class II invariant chain
chr12_+_113344582 Show fit	21.60	ENST00000202917.5 ENST00000445409.2 ENST00000452357.2	OAS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr18_+_48405419 Show fit	21.49	ENST00000321341.5	ME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	malic enzyme 2, NAD(+)-dependent, mitochondrial
chr1_-_25291475 Show fit	21.43	ENST00000338888.3 ENST00000399916.1	RUNX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	runt-related transcription factor 3
chr3_-_146262428 Show fit	21.30	ENST00000486631.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr6_-_32920794 Show fit	21.18	ENST00000395305.3 ENST00000395303.3 ENST00000374843.4 ENST00000429234.1	HLA-DMA Links Ensembl NCBI GeneCards UniProt NextProt Show fit XXbac-BPG181M17.5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DM alpha Uncharacterized protein
chr2_+_201994042 Show fit	21.15	ENST00000417748.1	CFLAR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CASP8 and FADD-like apoptosis regulator
chr22_+_39436862 Show fit	21.08	ENST00000381565.2 ENST00000452957.2	APOBEC3F Links Ensembl NCBI GeneCards UniProt NextProt Show fit APOBEC3G Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr3_+_151986709 Show fit	21.08	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscleblind-like splicing regulator 1
chr1_-_27998689 Show fit	21.00	ENST00000339145.4 ENST00000362020.4 ENST00000361157.6	IFI6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon, alpha-inducible protein 6
chr4_-_103748271 Show fit	20.85	ENST00000343106.5	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr2_+_202122703 Show fit	20.82	ENST00000447616.1 ENST00000358485.4	CASP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	caspase 8, apoptosis-related cysteine peptidase
chr6_+_29691198 Show fit	20.77	ENST00000440587.2 ENST00000434407.2	HLA-F Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, F
chr5_-_96143602 Show fit	20.55	ENST00000443439.2 ENST00000503921.1 ENST00000508227.1 ENST00000507154.1	ERAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	endoplasmic reticulum aminopeptidase 1
chr1_+_165864800 Show fit	20.47	ENST00000469256.2	UCK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	uridine-cytidine kinase 2
chr10_+_91152303 Show fit	20.46	ENST00000371804.3	IFIT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon-induced protein with tetratricopeptide repeats 1
chr2_+_86669118 Show fit	20.30	ENST00000427678.1 ENST00000542128.1	KDM3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 3A
chr6_+_26402465 Show fit	20.29	ENST00000476549.2 ENST00000289361.6 ENST00000450085.2 ENST00000425234.2 ENST00000427334.1 ENST00000506698.1	BTN3A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin, subfamily 3, member A1
chr6_+_29691056 Show fit	20.16	ENST00000414333.1 ENST00000334668.4 ENST00000259951.7	HLA-F Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, F
chr17_-_40264692 Show fit	20.14	ENST00000591220.1 ENST00000251642.3	DHX58 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEXH (Asp-Glu-X-His) box polypeptide 58
chr2_+_231191875 Show fit	20.11	ENST00000444636.1 ENST00000415673.2 ENST00000243810.6 ENST00000396563.4	SP140L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SP140 nuclear body protein-like
chr19_+_49838653 Show fit	19.98	ENST00000598095.1 ENST00000426897.2 ENST00000323906.4 ENST00000535669.2 ENST00000597602.1 ENST00000595660.1	CD37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD37 molecule
chr11_-_14358620 Show fit	19.92	ENST00000531421.1	RRAS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	related RAS viral (r-ras) oncogene homolog 2
chr11_+_5646213 Show fit	19.83	ENST00000429814.2	TRIM34 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 34
chr5_+_118690466 Show fit	19.51	ENST00000503646.1	TNFAIP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor, alpha-induced protein 8
chr14_-_35099315 Show fit	19.50	ENST00000396526.3 ENST00000396534.3 ENST00000355110.5 ENST00000557265.1	SNX6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorting nexin 6
chr2_+_85811525 Show fit	19.36	ENST00000306384.4	VAMP5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vesicle-associated membrane protein 5
chr2_+_86668464 Show fit	19.31	ENST00000409064.1	KDM3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 3A
chr3_+_152017181 Show fit	19.04	ENST00000498502.1 ENST00000324196.5 ENST00000545754.1 ENST00000357472.3	MBNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscleblind-like splicing regulator 1
chr14_+_91580777 Show fit	18.79	ENST00000525393.2 ENST00000428926.2 ENST00000517362.1	C14orf159 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 159
chr4_-_83765613 Show fit	18.75	ENST00000503937.1	SEC31A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC31 homolog A (S. cerevisiae)
chr17_+_18380051 Show fit	18.38	ENST00000581545.1 ENST00000582333.1 ENST00000328114.6 ENST00000412421.2 ENST00000583322.1 ENST00000584941.1	LGALS9C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lectin, galactoside-binding, soluble, 9C
chr1_+_165864821 Show fit	18.36	ENST00000470820.1	UCK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	uridine-cytidine kinase 2
chr6_-_170862322 Show fit	18.32	ENST00000262193.6	PSMB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 1
chr14_+_91581011 Show fit	18.30	ENST00000523894.1 ENST00000522322.1 ENST00000523771.1	C14orf159 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 159
chr13_+_53216565 Show fit	18.21	ENST00000357495.2	HNRNPA1L2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein A1-like 2
chr17_-_5342380 Show fit	18.01	ENST00000225698.4	C1QBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, q subcomponent binding protein
chr6_-_26056695 Show fit	17.79	ENST00000343677.2	HIST1H1C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone cluster 1, H1c
chr3_-_146262352 Show fit	17.36	ENST00000462666.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr3_-_146262637 Show fit	17.35	ENST00000472349.1 ENST00000342435.4	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr6_-_31239846 Show fit	17.25	ENST00000415537.1 ENST00000376228.5 ENST00000383329.3	HLA-C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, C
chr4_-_103747011 Show fit	17.19	ENST00000350435.7	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr11_-_73687997 Show fit	17.19	ENST00000545212.1	UCP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	uncoupling protein 2 (mitochondrial, proton carrier)
chr4_-_103746683 Show fit	16.88	ENST00000504211.1 ENST00000508476.1	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr11_+_60223225 Show fit	16.76	ENST00000524807.1 ENST00000345732.4	MS4A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane-spanning 4-domains, subfamily A, member 1
chr14_+_91580732 Show fit	16.75	ENST00000519019.1 ENST00000523816.1 ENST00000517518.1	C14orf159 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 159
chr1_+_64058939 Show fit	16.73	ENST00000371084.3	PGM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoglucomutase 1
chr1_-_153919128 Show fit	16.68	ENST00000361217.4	DENND4B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DENN/MADD domain containing 4B
chr11_-_65381643 Show fit	16.61	ENST00000309100.3 ENST00000529839.1 ENST00000526293.1	MAP3K11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase kinase kinase 11
chr3_-_167452262 Show fit	16.53	ENST00000487947.2	PDCD10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	programmed cell death 10
chr1_-_19426149 Show fit	16.45	ENST00000429347.2	UBR4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin protein ligase E3 component n-recognin 4
chr12_+_75874460 Show fit	16.36	ENST00000266659.3	GLIPR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GLI pathogenesis-related 1
chr11_+_313503 Show fit	16.35	ENST00000528780.1 ENST00000328221.5	IFITM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon induced transmembrane protein 1
chr11_+_60223312 Show fit	16.14	ENST00000532491.1 ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1	MS4A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane-spanning 4-domains, subfamily A, member 1
chr1_+_158149737 Show fit	16.00	ENST00000368171.3	CD1D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD1d molecule
chr22_-_36556821 Show fit	15.91	ENST00000531095.1 ENST00000397293.2 ENST00000349314.2	APOL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein L, 3
chr3_-_146262293 Show fit	15.71	ENST00000448205.1	PLSCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 1
chr2_-_225434538 Show fit	15.71	ENST00000409096.1	CUL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cullin 3
chr17_+_41158742 Show fit	15.65	ENST00000415816.2 ENST00000438323.2	IFI35 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon-induced protein 35
chr11_-_67169265 Show fit	15.24	ENST00000358239.4 ENST00000376745.4	PPP1CA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, catalytic subunit, alpha isozyme
chrX_+_80457442 Show fit	15.18	ENST00000373212.5	SH3BGRL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 domain binding glutamic acid-rich protein like
chr3_+_38179969 Show fit	15.11	ENST00000396334.3 ENST00000417037.2 ENST00000424893.1 ENST00000495303.1 ENST00000443433.2 ENST00000421516.1	MYD88 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myeloid differentiation primary response 88
chr5_+_133861790 Show fit	15.03	ENST00000395003.1	PHF15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	jade family PHD finger 2
chr16_+_50776021 Show fit	14.98	ENST00000566679.2 ENST00000564634.1 ENST00000398568.2	CYLD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cylindromatosis (turban tumor syndrome)
chrX_-_20236970 Show fit	14.97	ENST00000379548.4	RPS6KA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S6 kinase, 90kDa, polypeptide 3
chrX_+_70503037 Show fit	14.97	ENST00000535149.1	NONO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	non-POU domain containing, octamer-binding
chr10_+_51572408 Show fit	14.95	ENST00000374082.1	NCOA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor coactivator 4
chr9_-_32526184 Show fit	14.92	ENST00000545044.1 ENST00000379868.1	DDX58 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
44.8	223.8	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
42.8	128.5	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
34.3	274.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
32.8	98.3	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
28.3	84.9	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
28.1	28.1	GO:0002590	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
25.4	101.6	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
21.6	280.9	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
21.1	105.6	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
20.7	82.7	GO:0072308	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
19.9	219.3	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
19.0	57.0	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
17.5	52.5	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
16.6	49.7	GO:1900369	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
16.5	49.5	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
15.4	46.2	GO:0035915	pore formation in membrane of other organism(GO:0035915)
15.2	121.9	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
15.2	152.2	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
15.2	45.5	GO:0002585	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
13.8	69.0	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
13.2	39.6	GO:0007290	spermatid nucleus elongation(GO:0007290)
12.1	60.3	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
11.8	11.8	GO:0034165	regulation of toll-like receptor 9 signaling pathway(GO:0034163) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
11.6	46.3	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
11.5	46.1	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
11.5	103.4	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
11.2	67.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
11.1	89.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
10.4	1007.3	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
10.1	40.4	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
9.7	38.8	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
9.5	47.3	GO:0002905	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
9.0	27.0	GO:0039516	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
8.8	70.3	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
7.8	54.6	GO:0018377	protein myristoylation(GO:0018377)
7.8	31.2	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
7.6	22.8	GO:0002276	basophil activation involved in immune response(GO:0002276)
7.3	22.0	GO:1990108	protein linear deubiquitination(GO:1990108)
7.1	28.5	GO:1902990	leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
6.9	27.6	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
6.8	20.5	GO:0051097	negative regulation of helicase activity(GO:0051097)
6.7	6.7	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
6.6	39.7	GO:1901098	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
6.6	32.9	GO:0072642	positive regulation of interferon-beta secretion(GO:0035549) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
6.4	44.6	GO:1902031	regulation of NADP metabolic process(GO:1902031)
5.9	293.4	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
5.7	22.8	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
5.3	21.2	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
4.9	24.5	GO:0080009	mRNA methylation(GO:0080009)
4.9	24.5	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
4.6	36.5	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
4.5	49.0	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
4.4	35.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
4.4	35.2	GO:0035457	cellular response to interferon-alpha(GO:0035457)
4.3	17.4	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
4.3	13.0	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
4.1	12.3	GO:0045062	extrathymic T cell selection(GO:0045062)
4.0	16.0	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
4.0	23.8	GO:0070383	DNA cytosine deamination(GO:0070383)
3.9	15.7	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
3.9	19.5	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
3.9	70.1	GO:0045838	positive regulation of membrane potential(GO:0045838)
3.8	46.0	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
3.8	15.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
3.7	43.9	GO:0035455	response to interferon-alpha(GO:0035455)
3.6	10.9	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
3.6	10.9	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
3.6	82.8	GO:0072643	interferon-gamma secretion(GO:0072643)
3.6	14.3	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
3.3	23.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
3.3	23.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
3.2	12.8	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
3.1	12.4	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
2.9	8.8	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
2.9	11.7	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
2.9	8.7	GO:1903028	positive regulation of opsonization(GO:1903028)
2.9	20.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
2.8	2.8	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
2.8	25.1	GO:0016584	nucleosome positioning(GO:0016584)
2.8	16.7	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
2.7	8.1	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
2.7	10.8	GO:0090527	actin filament reorganization(GO:0090527)
2.6	15.9	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
2.6	7.9	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
2.6	10.4	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
2.6	46.4	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
2.5	7.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
2.5	7.4	GO:0032621	central nervous system myelin formation(GO:0032289) interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661) toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
2.5	17.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
2.5	12.3	GO:0006741	NADP biosynthetic process(GO:0006741)
2.4	116.1	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
2.4	16.6	GO:0007256	activation of JNKK activity(GO:0007256)
2.4	9.4	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
2.3	106.5	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
2.2	29.1	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
2.2	10.9	GO:0033625	positive regulation of integrin activation(GO:0033625)
2.2	8.7	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
2.2	6.5	GO:0007518	myoblast fate determination(GO:0007518)
2.1	10.7	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
2.1	4.1	GO:0042256	mature ribosome assembly(GO:0042256)
2.0	13.9	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
2.0	4.0	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
1.9	5.8	GO:0045918	negative regulation of cytolysis(GO:0045918)
1.9	7.8	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
1.9	15.5	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.9	5.8	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
1.9	3.8	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
1.9	5.6	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
1.8	3.6	GO:0006059	hexitol metabolic process(GO:0006059)
1.8	5.4	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.8	34.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
1.8	5.4	GO:0071283	cellular response to iron(III) ion(GO:0071283)
1.8	32.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
1.8	3.6	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
1.8	10.6	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.7	6.9	GO:0016554	cytidine to uridine editing(GO:0016554)
1.7	39.1	GO:0016578	histone deubiquitination(GO:0016578)
1.7	76.3	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
1.7	5.0	GO:2000653	regulation of genetic imprinting(GO:2000653)
1.7	9.9	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152) positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.7	5.0	GO:1903925	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.6	95.2	GO:0002260	lymphocyte homeostasis(GO:0002260)
1.6	8.2	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.6	19.6	GO:0010623	programmed cell death involved in cell development(GO:0010623)
1.6	14.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
1.6	19.4	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
1.6	9.4	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
1.6	14.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.5	7.7	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.5	63.1	GO:0006536	glutamate metabolic process(GO:0006536)
1.5	5.9	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.5	7.3	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
1.5	2.9	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
1.5	2.9	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
1.5	2.9	GO:0072300	positive regulation of metanephric glomerulus development(GO:0072300)
1.4	5.8	GO:0005986	sucrose biosynthetic process(GO:0005986)
1.4	53.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
1.4	114.2	GO:0031338	regulation of vesicle fusion(GO:0031338)
1.4	18.5	GO:0019388	galactose catabolic process(GO:0019388)
1.4	15.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
1.4	6.8	GO:0070836	caveola assembly(GO:0070836)
1.4	13.5	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
1.3	4.0	GO:0002384	hepatic immune response(GO:0002384)
1.3	4.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
1.3	6.7	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
1.3	140.8	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
1.3	3.8	GO:0021569	rhombomere 3 development(GO:0021569)
1.2	13.7	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
1.2	26.0	GO:0032897	negative regulation of viral transcription(GO:0032897)
1.2	100.3	GO:0006906	vesicle fusion(GO:0006906)
1.2	4.8	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
1.2	3.6	GO:0071492	cellular response to UV-A(GO:0071492)
1.2	4.7	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
1.2	6.9	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
1.1	21.8	GO:0008053	mitochondrial fusion(GO:0008053)
1.1	6.8	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
1.1	3.3	GO:2000391	positive regulation of neutrophil extravasation(GO:2000391) positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.0	1.0	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
1.0	3.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
1.0	5.1	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.0	1.0	GO:0048087	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of developmental pigmentation(GO:0048087) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
1.0	2.9	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
1.0	4.8	GO:0097338	response to clozapine(GO:0097338)
1.0	7.6	GO:0090344	negative regulation of cell aging(GO:0090344)
0.9	18.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.9	0.9	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.9	8.1	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.9	10.6	GO:1904896	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.9	3.5	GO:0043335	protein unfolding(GO:0043335)
0.9	10.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.9	4.3	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.9	11.1	GO:0016180	snRNA processing(GO:0016180)
0.9	5.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.8	7.5	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.8	5.8	GO:1902416	positive regulation of mRNA binding(GO:1902416)
0.8	4.9	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.8	14.6	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.8	4.0	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.8	5.6	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.8	28.6	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.8	11.9	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.8	6.2	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.8	12.2	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.8	7.7	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.8	7.6	GO:0015886	heme transport(GO:0015886)
0.8	3.8	GO:1902952	positive regulation of dendritic spine maintenance(GO:1902952)
0.8	6.0	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.8	3.0	GO:0043248	proteasome assembly(GO:0043248)
0.7	14.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.7	5.2	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.7	2.2	GO:0048075	positive regulation of eye pigmentation(GO:0048075)
0.7	2.2	GO:2001045	closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.7	37.5	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.7	15.1	GO:0006828	manganese ion transport(GO:0006828)
0.7	7.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.7	3.6	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.7	15.0	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.7	2.8	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.7	3.4	GO:0006581	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.7	11.6	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.7	5.4	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.6	5.2	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.6	3.8	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.6	16.1	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.6	3.0	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.6	1.7	GO:0070842	aggresome assembly(GO:0070842)
0.6	1.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.6	14.9	GO:0003094	glomerular filtration(GO:0003094)
0.6	10.8	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.6	11.9	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.6	27.7	GO:0006298	mismatch repair(GO:0006298)
0.6	29.8	GO:0051205	protein insertion into membrane(GO:0051205)
0.6	3.3	GO:1990441	negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.6	3.9	GO:0097319	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.6	4.4	GO:0015867	ADP transport(GO:0015866) ATP transport(GO:0015867) adenine nucleotide transport(GO:0051503)
0.5	4.9	GO:0071763	nuclear membrane organization(GO:0071763)
0.5	10.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.5	7.3	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.5	9.4	GO:0006622	protein targeting to lysosome(GO:0006622)
0.5	0.5	GO:1990791	dorsal root ganglion development(GO:1990791)
0.5	2.0	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5	10.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.5	6.3	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.5	6.3	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.5	10.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.5	1.9	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.5	30.2	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.4	1.3	GO:0009726	detection of endogenous stimulus(GO:0009726)
0.4	4.3	GO:0038092	nodal signaling pathway(GO:0038092)
0.4	4.8	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.4	6.8	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.4	12.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.4	2.4	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.4	1.2	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.4	1.2	GO:0070541	response to platinum ion(GO:0070541)
0.4	1.5	GO:0070874	negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.4	2.6	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.4	2.6	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.4	4.1	GO:0033227	dsRNA transport(GO:0033227)
0.4	3.3	GO:0021815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.4	1.8	GO:0002115	store-operated calcium entry(GO:0002115)
0.3	10.1	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.3	35.0	GO:0043484	regulation of RNA splicing(GO:0043484)
0.3	13.0	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.3	2.7	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3	9.0	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.3	1.0	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.3	6.1	GO:0032418	lysosome localization(GO:0032418)
0.3	5.1	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.3	0.6	GO:1904252	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.3	1.2	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3	3.3	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.3	5.7	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3	45.1	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.3	1.8	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.3	2.6	GO:0001783	B cell apoptotic process(GO:0001783)
0.3	0.6	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.3	1.1	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.3	3.7	GO:0043583	ear development(GO:0043583) inner ear development(GO:0048839)
0.3	5.3	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.3	0.8	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3	6.1	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.3	1.9	GO:0006105	succinate metabolic process(GO:0006105)
0.3	6.6	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3	1.4	GO:0036258	multivesicular body organization(GO:0036257) multivesicular body assembly(GO:0036258)
0.3	6.3	GO:0014904	myotube cell development(GO:0014904)
0.3	0.8	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.3	1.0	GO:0090309	regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3	2.8	GO:0072520	seminiferous tubule development(GO:0072520)
0.3	4.3	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3	8.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.2	1.7	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.2	13.9	GO:0043966	histone H3 acetylation(GO:0043966)
0.2	3.5	GO:0051639	actin filament network formation(GO:0051639)
0.2	6.3	GO:0006491	N-glycan processing(GO:0006491)
0.2	10.5	GO:0051972	regulation of telomerase activity(GO:0051972)
0.2	7.5	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.2	6.6	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.2	15.8	GO:0002456	T cell mediated immunity(GO:0002456)
0.2	11.2	GO:0045576	mast cell activation(GO:0045576)
0.2	3.0	GO:0003014	renal system process(GO:0003014)
0.2	29.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2	6.5	GO:2001240	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.2	8.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2	5.5	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.2	2.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2	5.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2	2.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.2	12.5	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	5.6	GO:0043171	peptide catabolic process(GO:0043171)
0.2	3.0	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.2	1.0	GO:0051012	microtubule sliding(GO:0051012)
0.2	4.9	GO:0000724	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.2	3.1	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2	8.4	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2	0.5	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.2	0.5	GO:0001897	cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1	3.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	9.9	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1	0.3	GO:0071698	olfactory placode formation(GO:0030910) ureteric bud formation(GO:0060676) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) mesonephric tubule formation(GO:0072172) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	7.1	GO:0006968	cellular defense response(GO:0006968)
0.1	1.6	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1	0.6	GO:0006574	valine catabolic process(GO:0006574)
0.1	11.5	GO:0008652	cellular amino acid biosynthetic process(GO:0008652)
0.1	0.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	1.2	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.1	8.3	GO:0006413	translational initiation(GO:0006413)
0.1	0.7	GO:0001712	ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1	5.4	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.1	53.9	GO:0016032	viral process(GO:0016032)
0.1	1.6	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.7	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	3.1	GO:0006342	chromatin silencing(GO:0006342)
0.1	1.3	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.1	2.6	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.1	1.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	2.2	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.1	0.5	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.1	1.1	GO:0033151	V(D)J recombination(GO:0033151)
0.1	2.5	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	1.5	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	4.0	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	0.2	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1	0.5	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.1	9.7	GO:0008360	regulation of cell shape(GO:0008360)
0.1	4.1	GO:0030641	regulation of cellular pH(GO:0030641)
0.1	2.7	GO:0048477	oogenesis(GO:0048477)
0.1	3.2	GO:0006400	tRNA modification(GO:0006400)
0.1	3.6	GO:0030193	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0	0.7	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.7	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0	0.1	GO:0005988	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0	2.0	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	3.2	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.0	3.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	1.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.4	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.2	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.2	GO:0043473	pigmentation(GO:0043473)
0.0	0.5	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	1.2	GO:0015992	proton transport(GO:0015992)
0.0	1.0	GO:0030574	collagen catabolic process(GO:0030574)
0.0	2.4	GO:0000086	G2/M transition of mitotic cell cycle(GO:0000086)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
69.7	557.8	GO:1990111	spermatoproteasome complex(GO:1990111)
30.6	183.7	GO:0042825	TAP complex(GO:0042825)
24.4	146.4	GO:0008537	proteasome activator complex(GO:0008537)
23.8	142.6	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
17.8	89.1	GO:0071797	LUBAC complex(GO:0071797)
11.8	129.6	GO:0042612	MHC class I protein complex(GO:0042612)
11.5	34.5	GO:0044393	microspike(GO:0044393)
10.7	85.5	GO:0032010	phagolysosome(GO:0032010)
9.9	49.7	GO:0044530	supraspliceosomal complex(GO:0044530)
9.7	116.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
9.6	173.1	GO:0097342	ripoptosome(GO:0097342)
9.5	28.5	GO:0070557	PCNA-p21 complex(GO:0070557)
7.0	21.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
6.7	53.9	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
6.2	130.3	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
6.2	49.5	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
5.7	22.8	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
5.7	34.0	GO:0030905	retromer, tubulation complex(GO:0030905)
5.6	39.0	GO:0030870	Mre11 complex(GO:0030870)
5.0	54.8	GO:0005688	U6 snRNP(GO:0005688)
5.0	14.9	GO:0071751	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
4.6	59.8	GO:0043020	NADPH oxidase complex(GO:0043020)
4.3	34.1	GO:0043196	varicosity(GO:0043196)
4.0	40.5	GO:0042587	glycogen granule(GO:0042587)
4.0	32.1	GO:0070552	BRISC complex(GO:0070552)
3.7	11.2	GO:0036398	TCR signalosome(GO:0036398)
3.2	29.0	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
3.1	21.6	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
3.0	14.8	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
2.9	202.5	GO:0015030	Cajal body(GO:0015030)
2.9	14.4	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.8	205.2	GO:0035577	azurophil granule membrane(GO:0035577)
2.8	8.4	GO:1990622	CHOP-ATF3 complex(GO:1990622)
2.6	7.7	GO:0005674	transcription factor TFIIF complex(GO:0005674)
2.5	7.4	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.5	27.0	GO:0035631	CD40 receptor complex(GO:0035631)
2.4	7.3	GO:0031213	RSF complex(GO:0031213)
2.4	28.9	GO:0044754	autolysosome(GO:0044754)
2.4	7.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
2.2	4.4	GO:0042824	MHC class I peptide loading complex(GO:0042824)
2.0	8.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
1.9	15.0	GO:0042382	paraspeckles(GO:0042382)
1.8	60.5	GO:0031258	lamellipodium membrane(GO:0031258)
1.8	3.6	GO:0097454	Schwann cell microvillus(GO:0097454)
1.8	8.9	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
1.7	15.7	GO:0005827	polar microtubule(GO:0005827)
1.7	11.6	GO:0072487	MSL complex(GO:0072487)
1.5	10.7	GO:0002178	palmitoyltransferase complex(GO:0002178)
1.4	13.9	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.3	162.6	GO:0005643	nuclear pore(GO:0005643)
1.3	12.6	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
1.3	5.0	GO:0070985	TFIIK complex(GO:0070985)
1.2	11.1	GO:0032039	integrator complex(GO:0032039)
1.2	3.5	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.1	10.3	GO:0072546	ER membrane protein complex(GO:0072546)
1.1	7.9	GO:0070765	gamma-secretase complex(GO:0070765)
1.1	30.2	GO:0070822	Sin3-type complex(GO:0070822)
1.1	7.7	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
1.1	38.0	GO:0000421	autophagosome membrane(GO:0000421)
1.1	21.2	GO:0042611	MHC protein complex(GO:0042611)
1.0	8.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
1.0	4.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.0	5.0	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.9	4.7	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.9	26.9	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.9	59.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.8	7.4	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.8	18.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.8	8.2	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.8	9.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.8	338.1	GO:0016607	nuclear speck(GO:0016607)
0.7	8.9	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.7	15.5	GO:0030686	90S preribosome(GO:0030686)
0.7	13.2	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.7	21.0	GO:0032839	dendrite cytoplasm(GO:0032839)
0.7	32.5	GO:0099738	cell cortex region(GO:0099738)
0.7	4.9	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.7	2.0	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.6	1.9	GO:0005588	collagen type V trimer(GO:0005588)
0.6	17.8	GO:0005719	nuclear euchromatin(GO:0005719)
0.6	5.6	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.6	3.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.6	10.3	GO:0045277	respiratory chain complex IV(GO:0045277)
0.6	57.1	GO:0035578	azurophil granule lumen(GO:0035578)
0.6	14.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.6	13.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.6	100.5	GO:0000775	chromosome, centromeric region(GO:0000775)
0.6	8.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6	4.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.6	10.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6	11.8	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.6	179.4	GO:0031965	nuclear membrane(GO:0031965)
0.5	2.2	GO:0031085	BLOC-3 complex(GO:0031085)
0.5	10.9	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.5	232.7	GO:0010008	endosome membrane(GO:0010008)
0.5	27.3	GO:0001772	immunological synapse(GO:0001772)
0.5	1.9	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5	64.6	GO:0001650	fibrillar center(GO:0001650)
0.5	19.3	GO:0097542	ciliary tip(GO:0097542)
0.5	1.4	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.4	1.8	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.4	4.8	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.4	11.9	GO:0005776	autophagosome(GO:0005776)
0.4	76.6	GO:0005769	early endosome(GO:0005769)
0.4	3.8	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4	5.4	GO:0005577	fibrinogen complex(GO:0005577)
0.4	3.3	GO:0044327	dendritic spine head(GO:0044327)
0.4	4.8	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.4	6.3	GO:0000786	nucleosome(GO:0000786)
0.4	5.4	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.4	28.9	GO:1904724	tertiary granule lumen(GO:1904724)
0.4	24.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.4	17.7	GO:0005801	cis-Golgi network(GO:0005801)
0.4	10.5	GO:0005876	spindle microtubule(GO:0005876)
0.4	30.1	GO:0016363	nuclear matrix(GO:0016363)
0.4	172.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.4	14.0	GO:0016235	aggresome(GO:0016235)
0.3	2.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3	8.5	GO:0000118	histone deacetylase complex(GO:0000118)
0.3	7.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.3	4.8	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3	83.6	GO:0000790	nuclear chromatin(GO:0000790)
0.3	4.5	GO:0032059	bleb(GO:0032059)
0.3	0.3	GO:0061702	inflammasome complex(GO:0061702)
0.3	6.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.3	3.4	GO:0043083	synaptic cleft(GO:0043083)
0.3	31.5	GO:0005923	bicellular tight junction(GO:0005923)
0.2	6.2	GO:0005840	ribosome(GO:0005840)
0.2	2.8	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2	3.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	1.6	GO:0033269	internode region of axon(GO:0033269)
0.2	1.1	GO:0097149	centralspindlin complex(GO:0097149)
0.2	23.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.2	3.1	GO:0031105	septin complex(GO:0031105)
0.2	3.0	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.2	2.3	GO:0032993	protein-DNA complex(GO:0032993)
0.2	7.8	GO:0008023	transcription elongation factor complex(GO:0008023)
0.2	7.8	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	23.8	GO:0031225	anchored component of membrane(GO:0031225)
0.2	3.5	GO:0031143	pseudopodium(GO:0031143)
0.2	4.2	GO:0035580	specific granule lumen(GO:0035580)
0.2	1.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.2	20.9	GO:0005802	trans-Golgi network(GO:0005802)
0.2	16.3	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.2	5.9	GO:0031201	SNARE complex(GO:0031201)
0.2	42.6	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2	6.9	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.2	10.5	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.2	2.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.2	1.6	GO:0043296	apical junction complex(GO:0043296)
0.2	11.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	16.0	GO:0005635	nuclear envelope(GO:0005635)
0.2	0.6	GO:0035253	ciliary rootlet(GO:0035253)
0.1	11.7	GO:0005814	centriole(GO:0005814)
0.1	1.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	8.2	GO:0016605	PML body(GO:0016605)
0.1	1.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	51.5	GO:0000139	Golgi membrane(GO:0000139)
0.1	15.2	GO:0031968	mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.1	7.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	13.0	GO:0001726	ruffle(GO:0001726)
0.1	99.5	GO:0005739	mitochondrion(GO:0005739)
0.1	0.5	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	1.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.1	5.3	GO:0005604	basement membrane(GO:0005604)
0.1	10.2	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.1	3.7	GO:0000922	spindle pole(GO:0000922)
0.0	99.8	GO:0005654	nucleoplasm(GO:0005654)
0.0	8.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0031082	BLOC complex(GO:0031082)
0.0	1.0	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
42.8	128.5	GO:0008859	exoribonuclease II activity(GO:0008859)
38.2	228.9	GO:0046979	TAP2 binding(GO:0046979)
28.3	84.9	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
23.4	703.1	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
21.1	105.6	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
20.9	146.4	GO:0061133	endopeptidase activator activity(GO:0061133)
15.3	76.3	GO:0004771	sterol esterase activity(GO:0004771)
15.2	45.5	GO:0032090	Pyrin domain binding(GO:0032090)
13.8	165.3	GO:0031386	protein tag(GO:0031386)
13.4	40.1	GO:0001069	regulatory region RNA binding(GO:0001069)
12.6	63.1	GO:0047820	D-glutamate cyclase activity(GO:0047820)
11.1	121.9	GO:0017128	phospholipid scramblase activity(GO:0017128)
10.4	31.1	GO:0048030	disaccharide binding(GO:0048030)
9.9	308.3	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
9.9	49.5	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
9.5	57.0	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
9.3	55.6	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
8.9	53.4	GO:0042296	ISG15 transferase activity(GO:0042296)
8.5	85.5	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
8.3	82.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
7.9	23.6	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
7.4	44.6	GO:0008948	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
7.4	29.6	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
7.1	28.5	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
7.0	35.2	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
7.0	70.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
6.4	25.7	GO:0004000	adenosine deaminase activity(GO:0004000)
6.0	24.1	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
6.0	18.0	GO:0030984	kininogen binding(GO:0030984)
5.9	29.5	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
5.8	46.1	GO:0070087	chromo shadow domain binding(GO:0070087)
5.5	38.8	GO:0004849	uridine kinase activity(GO:0004849)
5.4	21.5	GO:0005151	interleukin-1, Type II receptor binding(GO:0005151)
5.1	46.2	GO:1901612	cardiolipin binding(GO:1901612)
4.9	24.5	GO:0008174	mRNA methyltransferase activity(GO:0008174)
4.2	16.6	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
4.1	103.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
4.0	16.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
3.9	15.7	GO:0031208	POZ domain binding(GO:0031208)
3.9	113.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
3.9	19.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
3.8	22.6	GO:0061649	ubiquitinated histone binding(GO:0061649)
3.5	42.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
3.3	20.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
3.3	59.8	GO:0019864	IgG binding(GO:0019864)
3.3	16.4	GO:0042289	MHC class II protein binding(GO:0042289)
3.1	9.3	GO:0098770	FBXO family protein binding(GO:0098770)
3.1	18.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
3.0	8.9	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
2.9	14.5	GO:1990460	leptin receptor binding(GO:1990460)
2.9	49.0	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
2.9	17.2	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
2.7	8.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
2.6	7.9	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
2.5	7.5	GO:0032184	SUMO polymer binding(GO:0032184)
2.4	266.0	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
2.4	33.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
2.4	7.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
2.3	6.8	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
2.2	91.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
2.2	8.8	GO:0097001	ceramide binding(GO:0097001)
2.2	22.0	GO:1990380	Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
2.2	65.3	GO:0023026	MHC class II protein complex binding(GO:0023026)
2.1	39.6	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
1.9	5.8	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
1.9	40.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
1.8	7.3	GO:0004074	biliverdin reductase activity(GO:0004074)
1.8	29.1	GO:0032036	myosin heavy chain binding(GO:0032036)
1.8	296.0	GO:0001047	core promoter binding(GO:0001047)
1.8	16.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
1.8	19.5	GO:0034452	dynactin binding(GO:0034452)
1.7	34.9	GO:0044548	S100 protein binding(GO:0044548)
1.7	8.7	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
1.7	5.1	GO:0004531	deoxyribonuclease II activity(GO:0004531)
1.7	40.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
1.7	9.9	GO:0035800	deubiquitinase activator activity(GO:0035800)
1.6	13.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
1.6	27.3	GO:0017154	semaphorin receptor activity(GO:0017154)
1.6	16.0	GO:0030882	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
1.6	15.5	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.4	5.8	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.4	7.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
1.4	8.5	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
1.4	20.3	GO:0031996	thioesterase binding(GO:0031996)
1.3	4.0	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.3	5.4	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
1.3	40.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.2	15.9	GO:0015279	store-operated calcium channel activity(GO:0015279)
1.1	22.8	GO:0070566	adenylyltransferase activity(GO:0070566)
1.1	14.6	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
1.1	4.5	GO:0055077	gap junction hemi-channel activity(GO:0055077)
1.1	8.9	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
1.1	6.6	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
1.1	21.8	GO:0051400	BH domain binding(GO:0051400)
1.1	36.9	GO:0051879	Hsp90 protein binding(GO:0051879)
1.1	7.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.0	7.3	GO:0001849	complement component C1q binding(GO:0001849)
1.0	13.6	GO:0005123	death receptor binding(GO:0005123)
1.0	10.4	GO:0048019	receptor antagonist activity(GO:0048019)
1.0	8.1	GO:0089720	caspase binding(GO:0089720)
1.0	3.0	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
1.0	3.0	GO:0033149	FFAT motif binding(GO:0033149)
0.9	14.1	GO:0048156	tau protein binding(GO:0048156)
0.9	34.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.9	47.0	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.8	42.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.8	6.7	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.8	11.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.8	3.3	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.8	22.6	GO:0042605	peptide antigen binding(GO:0042605)
0.8	12.0	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.8	5.5	GO:0008732	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.8	5.4	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.8	13.7	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.8	7.6	GO:0015232	heme transporter activity(GO:0015232)
0.8	12.8	GO:0005522	profilin binding(GO:0005522)
0.7	7.9	GO:0033592	RNA strand annealing activity(GO:0033592)
0.7	5.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.7	10.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.7	7.8	GO:0042834	peptidoglycan binding(GO:0042834)
0.7	2.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.7	4.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7	7.4	GO:0019211	phosphatase activator activity(GO:0019211)
0.7	1.3	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.7	4.0	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7	4.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.6	1.9	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.6	6.9	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.6	11.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.6	17.4	GO:0008143	poly(A) binding(GO:0008143)
0.6	18.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.6	0.6	GO:0099609	microtubule lateral binding(GO:0099609)
0.6	96.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.6	4.7	GO:0016778	diphosphotransferase activity(GO:0016778)
0.6	44.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.6	22.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.6	4.0	GO:0019863	IgE binding(GO:0019863)
0.6	190.8	GO:0003924	GTPase activity(GO:0003924)
0.6	3.3	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.6	3.9	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.6	4.4	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.5	23.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.5	7.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5	27.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.5	7.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.5	11.9	GO:0001968	fibronectin binding(GO:0001968)
0.5	10.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5	7.2	GO:0031491	nucleosome binding(GO:0031491)
0.4	17.5	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.4	25.9	GO:0035064	methylated histone binding(GO:0035064)
0.4	8.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.4	21.9	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.4	20.2	GO:0050681	androgen receptor binding(GO:0050681)
0.4	1.6	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.4	10.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4	4.7	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.4	2.9	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.4	6.8	GO:0070300	phosphatidic acid binding(GO:0070300)
0.4	8.6	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.4	10.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.4	12.8	GO:0004407	histone deacetylase activity(GO:0004407)
0.4	2.8	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.4	18.2	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3	2.8	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.3	1.0	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.3	34.6	GO:0043130	ubiquitin binding(GO:0043130)
0.3	2.9	GO:0035325	Toll-like receptor binding(GO:0035325)
0.3	17.8	GO:0031490	chromatin DNA binding(GO:0031490)
0.3	6.0	GO:0050811	GABA receptor binding(GO:0050811)
0.3	4.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3	63.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.3	13.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.3	3.4	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3	10.6	GO:0005319	lipid transporter activity(GO:0005319)
0.3	1.6	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.3	36.9	GO:0019903	protein phosphatase binding(GO:0019903)
0.3	3.2	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.3	0.8	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.3	10.2	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.3	38.6	GO:0003823	antigen binding(GO:0003823)
0.3	3.0	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	15.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.2	4.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.2	8.2	GO:0043531	ADP binding(GO:0043531)
0.2	2.7	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2	8.7	GO:0019894	kinesin binding(GO:0019894)
0.2	10.1	GO:0016831	carboxy-lyase activity(GO:0016831)
0.2	5.9	GO:0051010	microtubule plus-end binding(GO:0051010)
0.2	1.1	GO:0015086	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2	5.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	10.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.2	40.7	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2	1.2	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.2	2.5	GO:0008252	nucleotidase activity(GO:0008252)
0.2	2.1	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.2	4.9	GO:0001671	ATPase activator activity(GO:0001671)
0.2	22.5	GO:0017124	SH3 domain binding(GO:0017124)
0.2	3.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.2	5.0	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2	6.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	6.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2	6.6	GO:0031072	heat shock protein binding(GO:0031072)
0.1	0.6	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	1.7	GO:0070628	proteasome binding(GO:0070628)
0.1	2.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.1	2.8	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	7.4	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	2.0	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	49.3	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	24.4	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	5.7	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	1.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	23.2	GO:0030246	carbohydrate binding(GO:0030246)
0.1	2.5	GO:0003951	NAD+ kinase activity(GO:0003951)
0.1	0.7	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	5.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	6.1	GO:0001618	virus receptor activity(GO:0001618)
0.1	1.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.7	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	1.6	GO:0004697	protein kinase C activity(GO:0004697)
0.1	1.7	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	1.3	GO:0044390	ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	1.8	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	1.8	GO:0051082	unfolded protein binding(GO:0051082)
0.0	1.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	7.4	GO:0003712	transcription cofactor activity(GO:0003712)
0.0	0.6	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.5	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.7	GO:0019902	phosphatase binding(GO:0019902)
0.0	1.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.2	GO:0031402	sodium ion binding(GO:0031402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.7	94.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
6.0	179.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
3.4	92.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
2.8	116.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
2.5	193.5	PID RAC1 PATHWAY	RAC1 signaling pathway
1.7	270.5	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
1.6	44.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.5	35.6	PID TRAIL PATHWAY	TRAIL signaling pathway
1.5	53.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
1.5	26.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.5	31.9	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.4	76.9	PID AURORA B PATHWAY	Aurora B signaling
1.2	79.1	PID PLK1 PATHWAY	PLK1 signaling events
1.2	68.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
1.0	30.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
1.0	37.7	PID ALK1 PATHWAY	ALK1 signaling events
0.9	22.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.9	68.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.9	39.9	PID RHOA PATHWAY	RhoA signaling pathway
0.8	37.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.8	7.3	ST STAT3 PATHWAY	STAT3 Pathway
0.8	28.5	PID BARD1 PATHWAY	BARD1 signaling events
0.7	15.0	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.7	19.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.6	103.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.6	5.0	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6	20.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.6	20.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.5	12.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.5	21.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.5	1.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.4	10.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.4	10.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	13.1	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.3	2.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	47.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	19.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.3	12.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	24.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.2	11.9	PID E2F PATHWAY	E2F transcription factor network
0.2	5.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	17.1	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	9.0	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.4	PID AURORA A PATHWAY	Aurora A signaling
0.1	4.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	3.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	3.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	2.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	2.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	1.9	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	4.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	3.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	1.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	2.4	PID P73PATHWAY	p73 transcription factor network
0.0	0.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.8	231.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
17.0	170.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
11.6	855.2	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
10.1	808.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
7.6	143.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
7.0	203.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
6.6	235.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
5.2	244.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
4.9	82.8	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
4.5	66.9	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
3.6	53.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
2.4	28.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
2.3	21.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
2.2	70.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.1	40.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.0	36.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
1.4	17.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
1.3	36.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.2	35.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.1	27.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
1.1	16.8	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
1.1	38.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
1.1	9.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
1.0	21.8	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.0	20.5	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.9	17.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.9	18.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.9	41.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.9	20.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.8	83.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.8	43.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.8	60.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.7	25.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.7	10.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.7	31.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.7	14.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.7	34.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.7	6.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.6	11.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.6	114.5	REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	Genes involved in Class I MHC mediated antigen processing & presentation
0.6	16.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.6	14.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.6	46.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.6	5.0	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.5	66.4	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5	21.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.5	5.6	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.5	4.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.5	36.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.5	7.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.5	29.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.5	35.6	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.4	6.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.4	27.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.4	6.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.4	47.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.4	62.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.4	8.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.4	19.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3	11.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.3	3.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3	36.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.3	7.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.3	9.8	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.3	9.3	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.3	7.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	15.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	5.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2	4.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	22.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.2	4.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	5.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	1.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.2	3.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	8.6	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.2	5.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	3.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.2	6.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	7.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2	6.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	3.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	10.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	5.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	13.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	2.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	1.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	1.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.6	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	1.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.7	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism