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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for IRF7

Z-value: 1.50

Motif logo

Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_615728-0.291.2e-05Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_55237484 29.08 ENST00000394609.2
reticulon 4
chr2_-_151344172 28.03 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr12_+_19358228 27.27 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr4_+_41614909 24.42 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chrX_+_102631248 23.52 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102883620 22.61 ENST00000372626.3
transcription elongation factor A (SII)-like 1
chrX_+_103031421 20.71 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr12_-_50616382 20.62 ENST00000552783.1
LIM domain and actin binding 1
chrX_+_103031758 19.83 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr12_-_118498958 18.44 ENST00000315436.3
WD repeat and SOCS box containing 2
chr11_+_19799327 17.49 ENST00000540292.1
neuron navigator 2
chr10_+_91152303 17.09 ENST00000371804.3
interferon-induced protein with tetratricopeptide repeats 1
chr3_-_47950745 15.75 ENST00000429422.1
microtubule-associated protein 4
chr1_+_948803 15.46 ENST00000379389.4
ISG15 ubiquitin-like modifier
chr12_-_50616122 13.44 ENST00000552823.1
ENST00000552909.1
LIM domain and actin binding 1
chr12_-_26278030 13.44 ENST00000242728.4
basic helix-loop-helix family, member e41
chr5_+_140749803 13.42 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr15_+_65843130 13.41 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr15_+_80733570 13.28 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
aryl-hydrocarbon receptor nuclear translocator 2
chr9_-_36276966 13.18 ENST00000543356.2
ENST00000396594.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr8_+_80523321 12.91 ENST00000518111.1
stathmin-like 2
chr17_-_76975925 12.86 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
lectin, galactoside-binding, soluble, 3 binding protein
chr11_+_9406169 12.85 ENST00000379719.3
ENST00000527431.1
importin 7
chr7_+_75931861 12.67 ENST00000248553.6
heat shock 27kDa protein 1
chrX_-_13835461 12.42 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr14_-_69446034 11.92 ENST00000193403.6
actinin, alpha 1
chr1_-_149900122 11.91 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr14_-_102552659 11.90 ENST00000441629.2
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr8_+_26150628 11.84 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr4_+_41614720 11.76 ENST00000509277.1
LIM and calponin homology domains 1
chr11_+_69455855 11.45 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr5_+_140734570 11.43 ENST00000571252.1
protocadherin gamma subfamily A, 4
chr18_-_21977748 11.19 ENST00000399441.4
ENST00000319481.3
oxysterol binding protein-like 1A
chr21_-_27542972 11.18 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
amyloid beta (A4) precursor protein
chr14_+_58711539 10.90 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr14_-_69445968 10.87 ENST00000438964.2
actinin, alpha 1
chr14_+_73563735 10.84 ENST00000532192.1
RNA binding motif protein 25
chr9_+_33264861 10.67 ENST00000223500.8
charged multivesicular body protein 5
chr8_+_132916318 10.63 ENST00000254624.5
ENST00000522709.1
EFR3 homolog A (S. cerevisiae)
chr4_-_176923483 10.34 ENST00000280187.7
ENST00000512509.1
glycoprotein M6A
chr1_-_246357029 10.19 ENST00000391836.2
SET and MYND domain containing 3
chrX_+_102883887 10.15 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chr15_+_96875657 10.02 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr3_-_114035026 9.94 ENST00000570269.1
RP11-553L6.5
chr20_+_10199468 9.72 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chrX_-_13835147 9.62 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr12_-_54652060 9.43 ENST00000552562.1
chromobox homolog 5
chr9_+_33265011 9.39 ENST00000419016.2
charged multivesicular body protein 5
chr11_-_119293872 9.39 ENST00000524970.1
Thy-1 cell surface antigen
chr14_-_70883708 9.20 ENST00000256366.4
synaptojanin 2 binding protein
chr15_-_37393406 9.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr5_-_146461027 9.10 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
protein phosphatase 2, regulatory subunit B, beta
chr4_+_113739244 9.10 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ankyrin 2, neuronal
chr1_+_165796753 8.92 ENST00000367879.4
uridine-cytidine kinase 2
chr11_-_111794446 8.77 ENST00000527950.1
crystallin, alpha B
chr10_-_95242044 8.57 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chrX_-_20236970 8.51 ENST00000379548.4
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr7_-_123197733 8.49 ENST00000470123.1
ENST00000471770.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr9_-_21187598 8.49 ENST00000421715.1
interferon, alpha 4
chr1_-_21377383 8.41 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr2_-_37384175 8.21 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
eukaryotic translation initiation factor 2-alpha kinase 2
chr10_-_95241951 8.15 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr1_-_21377447 8.11 ENST00000374937.3
ENST00000264211.8
eukaryotic translation initiation factor 4 gamma, 3
chrX_+_21958674 8.04 ENST00000404933.2
spermine synthase
chr1_+_84630645 8.03 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_55352834 7.86 ENST00000371269.3
24-dehydrocholesterol reductase
chr4_-_87281224 7.86 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr7_-_134143841 7.84 ENST00000285930.4
aldo-keto reductase family 1, member B1 (aldose reductase)
chr8_+_85618155 7.78 ENST00000523850.1
ENST00000521376.1
RALY RNA binding protein-like
chrX_+_77154935 7.74 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chrX_+_146993534 7.68 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
fragile X mental retardation 1
chr17_-_47723943 7.41 ENST00000510476.1
ENST00000503676.1
speckle-type POZ protein
chrX_-_102941596 7.38 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
mortality factor 4 like 2
chr17_-_65362678 7.35 ENST00000357146.4
ENST00000356126.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chrX_+_21958814 7.23 ENST00000379404.1
ENST00000415881.2
spermine synthase
chrX_+_146993449 7.19 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
fragile X mental retardation 1
chr15_+_78832747 7.13 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
proteasome (prosome, macropain) subunit, alpha type, 4
chrX_+_56590002 7.08 ENST00000338222.5
ubiquilin 2
chr14_+_90864504 7.02 ENST00000544280.2
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_84630053 6.98 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_92919043 6.95 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr12_+_79258547 6.91 ENST00000457153.2
synaptotagmin I
chr18_+_12947981 6.90 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr2_-_55277692 6.82 ENST00000394611.2
reticulon 4
chr8_+_109455845 6.73 ENST00000220853.3
ER membrane protein complex subunit 2
chr15_+_96876340 6.72 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr6_+_63921351 6.71 ENST00000370659.1
FK506 binding protein 1C
chr9_-_21305312 6.66 ENST00000259555.4
interferon, alpha 5
chr10_+_91092241 6.59 ENST00000371811.4
interferon-induced protein with tetratricopeptide repeats 3
chrX_+_119737806 6.51 ENST00000371317.5
malignant T cell amplified sequence 1
chr4_-_87281196 6.47 ENST00000359221.3
mitogen-activated protein kinase 10
chr11_-_33757950 6.46 ENST00000533403.1
ENST00000528700.1
ENST00000527577.1
ENST00000395850.3
ENST00000351554.3
CD59 molecule, complement regulatory protein
chr11_-_321050 6.41 ENST00000399808.4
interferon induced transmembrane protein 3
chr9_-_21228221 6.30 ENST00000413767.2
interferon, alpha 17
chr4_-_139163491 6.29 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr7_+_134576151 6.23 ENST00000393118.2
caldesmon 1
chr11_+_46402297 6.15 ENST00000405308.2
midkine (neurite growth-promoting factor 2)
chrX_-_34675391 6.07 ENST00000275954.3
transmembrane protein 47
chr7_+_112063192 6.06 ENST00000005558.4
interferon-related developmental regulator 1
chr1_-_154580616 6.05 ENST00000368474.4
adenosine deaminase, RNA-specific
chr8_+_54764346 5.97 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr9_-_21202204 5.86 ENST00000239347.3
interferon, alpha 7
chr6_+_151561506 5.85 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr3_+_141106643 5.79 ENST00000514251.1
zinc finger and BTB domain containing 38
chr14_-_54908043 5.79 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr5_-_11589131 5.72 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chrX_-_48980098 5.68 ENST00000156109.5
G patch domain and KOW motifs
chr7_+_55177416 5.63 ENST00000450046.1
ENST00000454757.2
epidermal growth factor receptor
chr10_+_94352956 5.61 ENST00000260731.3
kinesin family member 11
chr2_-_190044480 5.59 ENST00000374866.3
collagen, type V, alpha 2
chr7_-_93519471 5.54 ENST00000451238.1
tissue factor pathway inhibitor 2
chr3_-_197026152 5.52 ENST00000419354.1
discs, large homolog 1 (Drosophila)
chr14_-_21924209 5.47 ENST00000557364.1
chromodomain helicase DNA binding protein 8
chr2_+_120687335 5.45 ENST00000544261.1
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr10_-_91174215 5.40 ENST00000371837.1
lipase A, lysosomal acid, cholesterol esterase
chr1_-_103574024 5.35 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
collagen, type XI, alpha 1
chr13_-_46543805 5.33 ENST00000378921.2
zinc finger CCCH-type containing 13
chr6_+_151561085 5.33 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr7_+_100797678 5.23 ENST00000337619.5
adaptor-related protein complex 1, sigma 1 subunit
chr10_+_95517660 5.22 ENST00000371413.3
leucine-rich, glioma inactivated 1
chr1_+_155829286 5.22 ENST00000368324.4
synaptotagmin XI
chr11_+_57480046 5.15 ENST00000378312.4
ENST00000278422.4
thioredoxin-related transmembrane protein 2
chr12_+_12878829 5.11 ENST00000326765.6
apolipoprotein L domain containing 1
chr15_+_42694573 5.10 ENST00000397200.4
ENST00000569827.1
calpain 3, (p94)
chrX_+_100878079 5.09 ENST00000471229.2
armadillo repeat containing, X-linked 3
chr17_+_3379284 5.05 ENST00000263080.2
aspartoacylase
chr16_-_4850471 5.05 ENST00000592019.1
ENST00000586153.1
rogdi homolog (Drosophila)
chr5_+_34915444 5.04 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr9_-_140353748 4.96 ENST00000371472.2
ENST00000371475.3
ENST00000265663.7
ENST00000437259.1
ENST00000392812.4
ENST00000371474.3
ENST00000371473.3
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr6_-_116601044 4.96 ENST00000368608.3
TSPY-like 1
chr4_-_77135046 4.95 ENST00000264896.2
scavenger receptor class B, member 2
chr12_+_15699286 4.95 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
protein tyrosine phosphatase, receptor type, O
chr5_-_11588907 4.94 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chrX_+_23682379 4.92 ENST00000379349.1
peroxiredoxin 4
chr11_+_46402583 4.89 ENST00000359803.3
midkine (neurite growth-promoting factor 2)
chr7_-_30066233 4.88 ENST00000222803.5
FK506 binding protein 14, 22 kDa
chr17_+_41363854 4.71 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
transmembrane protein 106A
chr14_-_35099315 4.69 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
sorting nexin 6
chr10_+_95517566 4.67 ENST00000542308.1
leucine-rich, glioma inactivated 1
chr7_+_100797726 4.67 ENST00000429457.1
adaptor-related protein complex 1, sigma 1 subunit
chrX_-_99891796 4.66 ENST00000373020.4
tetraspanin 6
chr7_-_42971759 4.63 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
proteasome (prosome, macropain) subunit, alpha type, 2
chr11_-_117186946 4.62 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr9_-_13175823 4.58 ENST00000545857.1
multiple PDZ domain protein
chr11_+_27062272 4.57 ENST00000529202.1
ENST00000533566.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr10_+_95517616 4.54 ENST00000371418.4
leucine-rich, glioma inactivated 1
chr8_+_101162812 4.52 ENST00000353107.3
ENST00000522439.1
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr13_-_30424821 4.48 ENST00000380680.4
ubiquitin-like 3
chr11_+_47600562 4.47 ENST00000263774.4
ENST00000529276.1
ENST00000528192.1
ENST00000530295.1
ENST00000534208.1
ENST00000534716.2
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
chr7_+_121513143 4.43 ENST00000393386.2
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chrX_+_80457442 4.41 ENST00000373212.5
SH3 domain binding glutamic acid-rich protein like
chr4_+_113568207 4.35 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr18_+_3451646 4.34 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGFB-induced factor homeobox 1
chr3_-_194393206 4.33 ENST00000265245.5
large 60S subunit nuclear export GTPase 1
chr20_-_33999766 4.28 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
ubiquinol-cytochrome c reductase complex assembly factor 1
chr3_+_154797877 4.28 ENST00000462745.1
ENST00000493237.1
membrane metallo-endopeptidase
chr21_-_35281399 4.28 ENST00000418933.1
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr15_+_80364901 4.18 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr8_+_97597148 4.17 ENST00000521590.1
syndecan 2
chr11_+_46402744 4.16 ENST00000533952.1
midkine (neurite growth-promoting factor 2)
chr3_-_42306248 4.16 ENST00000334681.5
cholecystokinin
chr19_+_17378278 4.14 ENST00000596335.1
ENST00000601436.1
ENST00000595632.1
BRISC and BRCA1 A complex member 1
chr9_-_21995300 4.13 ENST00000498628.2
cyclin-dependent kinase inhibitor 2A
chr6_-_131291572 4.07 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr20_-_3767324 4.03 ENST00000379751.4
centromere protein B, 80kDa
chr2_-_37899323 3.96 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr12_+_113376157 3.94 ENST00000228928.7
2'-5'-oligoadenylate synthetase 3, 100kDa
chr3_+_119316689 3.90 ENST00000273371.4
phospholipase A1 member A
chr12_-_51422017 3.84 ENST00000394904.3
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chrX_-_100914781 3.83 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
armadillo repeat containing, X-linked 2
chr9_+_21409146 3.80 ENST00000380205.1
interferon, alpha 8
chr18_+_3451584 3.78 ENST00000551541.1
TGFB-induced factor homeobox 1
chr10_+_115439630 3.76 ENST00000369318.3
caspase 7, apoptosis-related cysteine peptidase
chr11_+_35211429 3.74 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr17_-_46682321 3.70 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr14_-_100841670 3.70 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
tryptophanyl-tRNA synthetase
chr14_-_24615805 3.65 ENST00000560410.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr10_+_115439699 3.64 ENST00000369315.1
caspase 7, apoptosis-related cysteine peptidase
chr13_+_29233218 3.63 ENST00000380842.4
proteasome maturation protein
chr10_+_115439282 3.62 ENST00000369321.2
ENST00000345633.4
caspase 7, apoptosis-related cysteine peptidase
chr20_-_48732472 3.60 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
ubiquitin-conjugating enzyme E2 variant 1
chr17_-_38978847 3.60 ENST00000269576.5
keratin 10
chr20_+_25388293 3.59 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr18_+_3262954 3.58 ENST00000584539.1
myosin, light chain 12B, regulatory
chr9_-_32526299 3.56 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_-_48782259 3.55 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRY-like
chr2_-_188419200 3.53 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_+_17378159 3.52 ENST00000598188.1
ENST00000359435.4
ENST00000599474.1
ENST00000599057.1
ENST00000601043.1
ENST00000447614.2
BRISC and BRCA1 A complex member 1
chr1_-_94374946 3.52 ENST00000370238.3
glutamate-cysteine ligase, modifier subunit
chr12_-_27090896 3.51 ENST00000539625.1
ENST00000538727.1
asunder spermatogenesis regulator
chr2_+_169312350 3.51 ENST00000305747.6
ceramide synthase 6
chr13_+_53216565 3.50 ENST00000357495.2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr12_+_27863706 3.49 ENST00000081029.3
ENST00000538315.1
ENST00000542791.1
mitochondrial ribosomal protein S35
chr15_+_91643442 3.49 ENST00000394232.1
synaptic vesicle glycoprotein 2B
chr15_-_41624685 3.48 ENST00000560640.1
ENST00000220514.3
Opa interacting protein 5
chr16_+_14726672 3.46 ENST00000261658.2
ENST00000563971.1
bifunctional apoptosis regulator
chr12_-_58165870 3.45 ENST00000257848.7
methyltransferase like 1
chr19_+_30863271 3.44 ENST00000355537.3
zinc finger protein 536
chr15_+_63354769 3.42 ENST00000558910.1
tropomyosin 1 (alpha)
chr1_-_115300579 3.39 ENST00000358528.4
ENST00000525132.1
cold shock domain containing E1, RNA-binding

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
5.1 15.3 GO:0006597 spermine biosynthetic process(GO:0006597)
4.4 17.5 GO:0021564 vagus nerve development(GO:0021564)
4.2 16.7 GO:0009956 radial pattern formation(GO:0009956)
4.0 48.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
4.0 11.9 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
3.2 12.7 GO:0099640 axo-dendritic protein transport(GO:0099640)
3.1 9.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
3.1 12.3 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
3.0 14.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
3.0 11.9 GO:0043335 protein unfolding(GO:0043335)
2.9 14.5 GO:0097338 response to clozapine(GO:0097338)
2.6 15.7 GO:0051012 microtubule sliding(GO:0051012)
2.6 7.8 GO:0006059 hexitol metabolic process(GO:0006059) response to methylglyoxal(GO:0051595)
2.6 10.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
2.5 15.3 GO:0030421 defecation(GO:0030421)
2.3 6.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
2.3 38.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
2.2 11.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
2.2 8.9 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
2.2 22.0 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.2 6.5 GO:0002188 translation reinitiation(GO:0002188)
2.0 6.1 GO:0007518 myoblast fate determination(GO:0007518)
2.0 6.0 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
1.9 9.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.9 5.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.8 14.3 GO:0007258 JUN phosphorylation(GO:0007258)
1.7 5.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
1.7 6.7 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.7 5.0 GO:0006533 aspartate catabolic process(GO:0006533)
1.7 6.6 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.6 4.9 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
1.6 32.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
1.6 6.5 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
1.6 7.9 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
1.5 16.7 GO:0001778 plasma membrane repair(GO:0001778)
1.4 5.6 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.4 11.0 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.3 20.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
1.3 5.0 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
1.2 7.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.2 4.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.2 8.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
1.2 5.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
1.1 9.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.1 3.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.1 25.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
1.1 5.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.1 6.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.1 4.3 GO:0071492 cellular response to UV-A(GO:0071492)
1.0 7.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
1.0 11.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.0 9.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
1.0 13.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
1.0 3.0 GO:0006624 vacuolar protein processing(GO:0006624)
1.0 3.0 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
1.0 4.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.9 2.8 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.9 22.8 GO:0030220 platelet formation(GO:0030220)
0.9 3.6 GO:0043248 proteasome assembly(GO:0043248)
0.9 3.6 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.9 2.7 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.9 3.5 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.9 5.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.8 5.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.8 13.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.8 2.4 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.8 5.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.8 2.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.8 6.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.8 5.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.7 11.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 3.7 GO:1903588 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.7 2.9 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.7 6.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.7 2.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.7 2.1 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.7 10.2 GO:0006999 nuclear pore organization(GO:0006999)
0.7 2.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.7 4.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.6 1.9 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.6 4.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.6 11.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.6 4.2 GO:0008218 bioluminescence(GO:0008218)
0.6 35.0 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.6 2.9 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.6 2.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.6 2.3 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.6 4.4 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.5 4.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.5 4.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.5 5.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.5 8.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.5 6.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.5 4.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 5.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.4 3.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.4 6.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 1.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 3.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 2.1 GO:0015692 lead ion transport(GO:0015692)
0.4 2.5 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.4 1.3 GO:0086044 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.4 3.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 4.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 2.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 8.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.4 1.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.4 7.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 2.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 10.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 3.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 3.6 GO:0042118 endothelial cell activation(GO:0042118)
0.3 6.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 4.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 1.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 3.3 GO:0006554 lysine catabolic process(GO:0006554)
0.3 3.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.3 5.6 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 4.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 0.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.3 2.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.3 7.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.3 12.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.3 2.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.3 1.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 11.5 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.3 5.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.3 1.6 GO:0070383 DNA cytosine deamination(GO:0070383)
0.3 6.2 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.3 1.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.3 0.8 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.3 29.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 2.4 GO:0034214 protein hexamerization(GO:0034214)
0.3 2.6 GO:0060013 righting reflex(GO:0060013)
0.3 0.3 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.3 1.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 12.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.2 6.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 10.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.2 1.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 5.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.2 3.0 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)
0.2 1.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 0.7 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 2.9 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 13.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 2.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.2 2.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 9.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.2 1.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 15.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 2.4 GO:0051601 exocyst localization(GO:0051601)
0.2 0.6 GO:0071314 cellular response to cocaine(GO:0071314)
0.2 11.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 4.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.6 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.2 1.6 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 0.8 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.2 1.1 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 2.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.7 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.2 0.5 GO:1901524 regulation of macromitophagy(GO:1901524) positive regulation of macromitophagy(GO:1901526) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2 1.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 6.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 10.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 7.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 0.8 GO:0051552 flavone metabolic process(GO:0051552)
0.2 33.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.2 3.1 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.3 GO:0060437 lung growth(GO:0060437)
0.2 3.8 GO:0001783 B cell apoptotic process(GO:0001783)
0.2 1.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.0 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 5.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.3 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.1 1.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.1 2.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 4.5 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1 1.6 GO:0071285 cellular response to lithium ion(GO:0071285) establishment of integrated proviral latency(GO:0075713)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 6.1 GO:0008542 visual learning(GO:0008542)
0.1 1.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 3.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.5 GO:0030070 insulin processing(GO:0030070)
0.1 0.5 GO:1904141 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 4.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 2.8 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 3.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 1.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.8 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 2.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 3.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 5.8 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.1 9.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.1 8.4 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.1 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 32.3 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.1 0.2 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 1.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 1.7 GO:0043276 anoikis(GO:0043276)
0.1 5.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 9.9 GO:0007411 axon guidance(GO:0007411)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 2.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 5.8 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 1.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 2.5 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.7 GO:0021549 cerebellum development(GO:0021549)
0.0 0.4 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 2.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 1.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)
0.0 0.4 GO:0033189 response to vitamin A(GO:0033189)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 4.6 GO:0043687 post-translational protein modification(GO:0043687)
0.0 3.9 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 14.9 GO:0019034 viral replication complex(GO:0019034)
2.4 9.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.4 2.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
2.1 25.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
2.0 7.8 GO:0097454 Schwann cell microvillus(GO:0097454)
1.9 38.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.9 5.6 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
1.9 5.6 GO:0005588 collagen type V trimer(GO:0005588)
1.7 6.9 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.6 11.2 GO:1990812 growth cone filopodium(GO:1990812)
1.5 16.7 GO:0005614 interstitial matrix(GO:0005614)
1.5 4.4 GO:0072534 perineuronal net(GO:0072534)
1.5 22.1 GO:0005916 fascia adherens(GO:0005916)
1.4 9.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.3 5.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.2 6.0 GO:0044530 supraspliceosomal complex(GO:0044530)
1.1 3.4 GO:0018444 translation release factor complex(GO:0018444)
1.0 6.1 GO:0008537 proteasome activator complex(GO:0008537)
1.0 15.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.0 6.9 GO:0061700 GATOR2 complex(GO:0061700)
1.0 13.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.0 7.7 GO:0070552 BRISC complex(GO:0070552)
0.9 4.7 GO:0097422 tubular endosome(GO:0097422)
0.9 3.6 GO:0000811 GINS complex(GO:0000811)
0.9 6.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.8 2.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.8 16.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 6.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.7 25.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 7.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.7 3.6 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.7 12.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 13.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 3.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.7 6.7 GO:0097255 R2TP complex(GO:0097255)
0.7 6.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.7 7.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 9.2 GO:0030478 actin cap(GO:0030478)
0.6 6.6 GO:0016600 flotillin complex(GO:0016600)
0.6 5.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 3.0 GO:0033503 HULC complex(GO:0033503)
0.6 5.3 GO:0005915 zonula adherens(GO:0005915)
0.6 2.8 GO:0071797 LUBAC complex(GO:0071797)
0.5 14.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 11.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.5 10.3 GO:0044295 axonal growth cone(GO:0044295)
0.5 7.0 GO:0097512 cardiac myofibril(GO:0097512)
0.5 5.5 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 7.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.4 6.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.4 35.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 1.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 2.1 GO:0070826 paraferritin complex(GO:0070826)
0.4 11.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.4 5.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 2.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3 4.2 GO:0043203 axon hillock(GO:0043203)
0.3 5.8 GO:0032059 bleb(GO:0032059)
0.3 1.7 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 2.3 GO:0000813 ESCRT I complex(GO:0000813)
0.3 11.9 GO:0031430 M band(GO:0031430)
0.3 4.1 GO:0008091 spectrin(GO:0008091)
0.3 12.7 GO:1904115 axon cytoplasm(GO:1904115)
0.3 3.5 GO:0010369 chromocenter(GO:0010369)
0.3 1.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.3 2.3 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.3 4.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 3.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 4.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 6.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 3.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 12.6 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.2 16.4 GO:0072686 mitotic spindle(GO:0072686)
0.2 2.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 39.8 GO:0043209 myelin sheath(GO:0043209)
0.2 2.8 GO:0035102 PRC1 complex(GO:0035102)
0.2 2.4 GO:0005686 U2 snRNP(GO:0005686)
0.2 1.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.9 GO:0031905 early endosome lumen(GO:0031905)
0.2 5.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 2.5 GO:0001533 cornified envelope(GO:0001533)
0.2 11.4 GO:0005643 nuclear pore(GO:0005643)
0.2 2.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 3.6 GO:0099738 cell cortex region(GO:0099738)
0.2 5.6 GO:0005871 kinesin complex(GO:0005871)
0.2 0.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 1.3 GO:0042382 paraspeckles(GO:0042382)
0.1 8.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 7.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 4.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.8 GO:0070822 Sin3-type complex(GO:0070822)
0.1 7.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 8.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 6.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.7 GO:0005901 caveola(GO:0005901)
0.1 2.9 GO:0030686 90S preribosome(GO:0030686)
0.1 24.4 GO:0005770 late endosome(GO:0005770)
0.1 15.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 13.7 GO:0043204 perikaryon(GO:0043204)
0.1 2.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 7.1 GO:0005776 autophagosome(GO:0005776)
0.1 4.3 GO:0015030 Cajal body(GO:0015030)
0.1 3.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 2.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 13.7 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 3.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 3.1 GO:0042641 actomyosin(GO:0042641)
0.1 7.8 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.9 GO:0030425 dendrite(GO:0030425)
0.1 4.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 8.1 GO:0005840 ribosome(GO:0005840)
0.0 2.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 16.1 GO:0005925 focal adhesion(GO:0005925)
0.0 2.7 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 8.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 2.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.2 GO:0005874 microtubule(GO:0005874)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
3.4 40.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.0 14.9 GO:0034046 poly(G) binding(GO:0034046)
2.7 8.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
2.7 27.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
2.4 14.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.3 32.7 GO:0005132 type I interferon receptor binding(GO:0005132)
1.5 4.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.5 13.4 GO:0043426 MRF binding(GO:0043426)
1.4 6.9 GO:0030348 syntaxin-3 binding(GO:0030348)
1.3 10.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.3 15.5 GO:0031386 protein tag(GO:0031386)
1.3 8.9 GO:0004849 uridine kinase activity(GO:0004849)
1.2 11.9 GO:0030911 TPR domain binding(GO:0030911)
1.2 9.4 GO:0034235 GPI anchor binding(GO:0034235)
1.2 5.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
1.1 4.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.1 10.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.1 5.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.1 6.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
1.1 11.2 GO:0051425 PTB domain binding(GO:0051425)
1.1 13.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
1.1 5.4 GO:0004771 sterol esterase activity(GO:0004771)
1.0 7.0 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
1.0 2.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.9 12.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.9 15.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.9 3.6 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.9 3.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.9 7.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.9 6.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.9 5.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.8 18.6 GO:0000339 RNA cap binding(GO:0000339)
0.8 3.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.8 4.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.8 2.3 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.8 19.2 GO:0017166 vinculin binding(GO:0017166)
0.7 32.8 GO:0050699 WW domain binding(GO:0050699)
0.7 5.0 GO:0004046 aminoacylase activity(GO:0004046)
0.7 32.3 GO:0003785 actin monomer binding(GO:0003785)
0.7 2.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 11.8 GO:0048156 tau protein binding(GO:0048156)
0.6 4.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.6 7.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.6 3.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.6 2.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6 2.8 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.6 3.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.5 16.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 14.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.5 5.5 GO:0097016 L27 domain binding(GO:0097016)
0.5 2.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.5 2.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 12.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 12.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 11.4 GO:0070064 proline-rich region binding(GO:0070064)
0.4 3.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.4 0.9 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.4 3.5 GO:0089720 caspase binding(GO:0089720)
0.4 2.1 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.4 4.1 GO:0042731 PH domain binding(GO:0042731)
0.4 4.0 GO:0019237 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.4 5.6 GO:0031432 titin binding(GO:0031432)
0.4 3.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 1.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4 5.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 4.2 GO:0034452 dynactin binding(GO:0034452)
0.4 5.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 6.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 9.2 GO:0005523 tropomyosin binding(GO:0005523)
0.3 1.4 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.3 10.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 8.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 1.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 1.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 13.6 GO:0030507 spectrin binding(GO:0030507)
0.3 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.6 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 7.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 2.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 5.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.3 12.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 7.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 5.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 8.9 GO:0015248 sterol transporter activity(GO:0015248)
0.3 1.0 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.3 3.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 6.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 4.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 13.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.0 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 3.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 2.9 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 4.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 8.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 3.3 GO:0043495 protein anchor(GO:0043495)
0.2 15.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 6.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 3.9 GO:0005521 lamin binding(GO:0005521)
0.2 5.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 12.6 GO:0035064 methylated histone binding(GO:0035064)
0.2 6.5 GO:0001848 complement binding(GO:0001848)
0.2 6.6 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 8.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 3.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 5.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 6.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 74.2 GO:0045296 cadherin binding(GO:0045296)
0.2 1.3 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.2 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 13.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 5.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 12.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 4.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 18.6 GO:0004386 helicase activity(GO:0004386)
0.1 4.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.1 GO:0034236 cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.5 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 4.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.6 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1 3.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 10.2 GO:0005262 calcium channel activity(GO:0005262)
0.1 7.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 1.0 GO:0036122 BMP binding(GO:0036122)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 25.6 GO:0003924 GTPase activity(GO:0003924)
0.1 1.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 6.7 GO:0008565 protein transporter activity(GO:0008565)
0.1 2.9 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 11.8 GO:0008017 microtubule binding(GO:0008017)
0.1 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 4.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.4 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 4.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 18.8 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 2.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 9.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 3.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.0 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.0 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 104.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.9 59.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.8 18.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 11.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.4 8.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4 20.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 27.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.3 8.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 20.3 PID AURORA B PATHWAY Aurora B signaling
0.3 12.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 12.2 PID ATR PATHWAY ATR signaling pathway
0.2 5.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 2.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 3.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 6.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 7.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 6.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.2 14.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 8.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 5.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 10.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 11.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.5 PID MYC PATHWAY C-MYC pathway
0.1 4.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 11.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.2 PID FGF PATHWAY FGF signaling pathway
0.1 6.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 1.8 ST GA13 PATHWAY G alpha 13 Pathway
0.1 1.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 6.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.6 PID ATM PATHWAY ATM pathway
0.1 2.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 2.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.8 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 5.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 36.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.8 18.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.8 22.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.8 17.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.8 10.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8 43.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.7 14.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.7 11.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.6 18.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.6 15.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 65.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.5 15.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5 43.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.4 27.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.4 6.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 6.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 8.7 REACTOME KINESINS Genes involved in Kinesins
0.3 24.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3 2.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 8.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 15.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 5.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.3 8.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 7.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 8.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 20.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 3.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 11.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 8.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 12.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 6.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 7.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 1.9 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.2 4.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 6.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 4.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.2 1.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 2.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 4.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 7.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 7.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 7.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 4.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 3.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 2.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 3.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates