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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for IRX5

Z-value: 0.82

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Transcription factors associated with IRX5

Gene Symbol Gene ID Gene Info
IRX5
ENSG00000176842.10 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX5hg19_v2_chr16_+_54964740_54964789-0.143.4e-02Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_73563735 13.73 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr14_+_56127989 11.98 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr1_-_197115818 10.89 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr4_-_104119528 9.32 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chrX_+_49294472 8.93 ENST00000361446.5
GAGE12B
G antigen 12B
chrX_-_52258669 7.88 ENST00000441417.1
XAGE1A
X antigen family, member 1A
chrX_+_52513455 7.38 ENST00000446098.1
XAGE1C
X antigen family, member 1C
chr14_+_35747825 7.03 ENST00000540871.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr1_+_220267429 6.70 ENST00000366922.1
ENST00000302637.5
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr3_+_180586536 6.22 ENST00000465551.1
FXR1
fragile X mental retardation, autosomal homolog 1
chrX_+_12809463 6.10 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr6_+_37012607 6.05 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr5_+_169010638 5.69 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr1_-_115124257 5.68 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr16_-_58585513 5.57 ENST00000245138.4
ENST00000567285.1
CNOT1
CCR4-NOT transcription complex, subunit 1
chr12_-_76462713 5.55 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr9_+_42704004 5.48 ENST00000457288.1
CBWD7
COBW domain containing 7
chr7_-_87856280 5.36 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr3_+_158787041 5.32 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr8_-_67976509 5.26 ENST00000518747.1
COPS5
COP9 signalosome subunit 5
chr7_-_87856303 5.10 ENST00000394641.3
SRI
sorcin
chr4_+_113558612 5.09 ENST00000505034.1
ENST00000324052.6
LARP7
La ribonucleoprotein domain family, member 7
chrX_+_52240504 4.88 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chr1_-_241683001 4.87 ENST00000366560.3
FH
fumarate hydratase
chr11_+_114310102 4.79 ENST00000265881.5
REXO2
RNA exonuclease 2
chr1_-_110284384 4.58 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr5_+_96079240 4.55 ENST00000515663.1
CAST
calpastatin
chr8_-_101962777 4.44 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_-_32236002 4.39 ENST00000404530.1
MEMO1
mediator of cell motility 1
chr11_+_114310237 4.34 ENST00000539119.1
REXO2
RNA exonuclease 2
chr12_-_120315074 4.27 ENST00000261833.7
ENST00000392521.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr15_-_63448973 4.06 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr4_+_17616253 3.95 ENST00000237380.7
MED28
mediator complex subunit 28
chr15_-_64665911 3.85 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1
Uncharacterized protein
chr9_-_21202204 3.72 ENST00000239347.3
IFNA7
interferon, alpha 7
chr4_+_122722466 3.72 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
EXOSC9
exosome component 9
chr2_+_201173667 3.61 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr1_-_145826450 3.55 ENST00000462900.2
GPR89A
G protein-coupled receptor 89A
chr14_-_21737551 3.55 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr3_+_52245458 3.53 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr1_-_21377383 3.47 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr12_+_53848549 3.42 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr14_-_23623577 3.27 ENST00000422941.2
ENST00000453702.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr3_-_81792780 3.26 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr14_+_51706886 3.21 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr2_+_160590469 3.14 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr10_-_96829246 3.13 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr6_-_111804393 3.10 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr7_+_77469439 3.09 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr1_+_53480598 3.08 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr1_-_21377447 3.04 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_-_3566627 3.01 ENST00000419924.2
ENST00000270708.7
WRAP73
WD repeat containing, antisense to TP73
chr4_-_143481822 2.94 ENST00000510812.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr15_+_41057818 2.89 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr4_+_69962185 2.75 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr3_-_52713729 2.73 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr4_+_69962212 2.73 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr1_-_227505289 2.72 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr3_-_27498235 2.71 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_-_142232071 2.63 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr2_+_58655461 2.58 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr12_-_100486668 2.57 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L
UHRF1 binding protein 1-like
chr1_+_155579979 2.55 ENST00000452804.2
ENST00000538143.1
ENST00000245564.2
ENST00000368341.4
MSTO1
misato 1, mitochondrial distribution and morphology regulator
chr2_-_183106641 2.38 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_+_116502527 2.33 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr3_+_12392971 2.29 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr3_-_168865522 2.26 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr1_-_3566590 2.23 ENST00000424367.1
ENST00000378322.3
WRAP73
WD repeat containing, antisense to TP73
chr19_-_50266580 2.18 ENST00000246801.3
TSKS
testis-specific serine kinase substrate
chr7_-_16844611 2.09 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr6_-_111804905 2.07 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr2_-_88125471 2.03 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr4_+_75480629 1.99 ENST00000380846.3
AREGB
amphiregulin B
chr9_+_71819927 1.94 ENST00000535702.1
TJP2
tight junction protein 2
chr19_-_22379753 1.94 ENST00000397121.2
ZNF676
zinc finger protein 676
chr6_+_22569784 1.93 ENST00000510882.2
HDGFL1
hepatoma derived growth factor-like 1
chrX_-_15353629 1.93 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr9_+_71820057 1.88 ENST00000539225.1
TJP2
tight junction protein 2
chr21_-_34185944 1.82 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr15_-_44116873 1.78 ENST00000267812.3
MFAP1
microfibrillar-associated protein 1
chr2_-_231989808 1.70 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr4_+_76995855 1.69 ENST00000355810.4
ENST00000349321.3
ART3
ADP-ribosyltransferase 3
chr7_-_41742697 1.58 ENST00000242208.4
INHBA
inhibin, beta A
chr16_+_31539197 1.58 ENST00000564707.1
AHSP
alpha hemoglobin stabilizing protein
chr6_+_42584847 1.55 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_62190793 1.54 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr17_+_75447326 1.53 ENST00000591088.1
SEPT9
septin 9
chr10_-_35379524 1.48 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
CUL2
cullin 2
chr19_+_35849362 1.46 ENST00000327809.4
FFAR3
free fatty acid receptor 3
chr15_+_49170083 1.39 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr14_+_96722539 1.39 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr9_-_125667618 1.37 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr10_-_14050522 1.34 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr1_+_145524891 1.31 ENST00000369304.3
ITGA10
integrin, alpha 10
chrX_+_108779004 1.29 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr8_+_67976593 1.28 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr2_-_88427568 1.26 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr9_-_21166659 1.23 ENST00000380225.1
IFNA21
interferon, alpha 21
chr18_+_616672 1.23 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr3_-_46068969 1.22 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr1_+_113010056 1.20 ENST00000369686.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr2_+_173686303 1.18 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr21_-_34185989 1.17 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr15_-_56757329 1.14 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr3_+_173116225 1.07 ENST00000457714.1
NLGN1
neuroligin 1
chr4_+_75310851 1.06 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr9_+_105757590 1.05 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr7_+_66386204 1.04 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chr1_+_196857144 1.03 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4
chr1_+_10509971 0.97 ENST00000320498.4
CORT
cortistatin
chr15_+_66585879 0.92 ENST00000319212.4
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chr4_+_41361616 0.91 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr12_-_25102252 0.89 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr1_+_196743943 0.86 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr17_+_3379284 0.84 ENST00000263080.2
ASPA
aspartoacylase
chr14_+_22386325 0.82 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr22_-_24096562 0.73 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr16_+_87636474 0.71 ENST00000284262.2
JPH3
junctophilin 3
chr14_+_22993296 0.68 ENST00000390517.1
TRAJ20
T cell receptor alpha joining 20
chr21_-_34186006 0.68 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr4_+_70146217 0.61 ENST00000335568.5
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr16_+_31539183 0.61 ENST00000302312.4
AHSP
alpha hemoglobin stabilizing protein
chr10_+_96698406 0.58 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr3_-_72897545 0.57 ENST00000325599.8
SHQ1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr10_+_118350468 0.56 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1
pancreatic lipase-related protein 1
chr4_-_100356844 0.56 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_58018269 0.55 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chrY_+_23698778 0.53 ENST00000303902.5
RBMY1A1
RNA binding motif protein, Y-linked, family 1, member A1
chr1_+_67632083 0.52 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr8_+_27947746 0.51 ENST00000521015.1
ENST00000521570.1
ELP3
elongator acetyltransferase complex subunit 3
chr5_-_64064508 0.49 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr6_-_154677900 0.48 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr1_+_87012753 0.48 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr10_+_118350522 0.46 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1
pancreatic lipase-related protein 1
chr17_-_42327236 0.43 ENST00000399246.2
AC003102.1
AC003102.1
chr2_+_191792376 0.42 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr17_-_67264947 0.40 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr3_+_186383741 0.39 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr3_-_9994021 0.38 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr1_-_201438282 0.37 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr6_+_26217159 0.36 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr12_+_5541267 0.35 ENST00000423158.3
NTF3
neurotrophin 3
chr1_-_114355083 0.34 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr12_-_10282742 0.34 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr11_-_89653576 0.32 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr4_-_75695366 0.31 ENST00000512743.1
BTC
betacellulin
chr6_+_29429217 0.30 ENST00000396792.2
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr1_+_196743912 0.29 ENST00000367425.4
CFHR3
complement factor H-related 3
chr6_+_146920116 0.27 ENST00000367493.3
ADGB
androglobin
chr13_-_46716969 0.26 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_138790348 0.25 ENST00000414978.1
ENST00000519895.1
MCF2
MCF.2 cell line derived transforming sequence
chr14_+_72052983 0.23 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr8_-_108510224 0.20 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr16_-_20709066 0.18 ENST00000520010.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr8_+_125463048 0.17 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr17_+_41561317 0.16 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr12_-_102224704 0.16 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr6_-_26216872 0.14 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr21_+_38792602 0.12 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr11_-_104905840 0.10 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr13_+_24844819 0.09 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr18_+_6729725 0.08 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chrX_-_33229636 0.08 ENST00000357033.4
DMD
dystrophin
chrX_+_99899180 0.07 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr1_-_116383738 0.05 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr12_-_21757774 0.05 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr3_+_171561127 0.03 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr11_+_22688150 0.02 ENST00000454584.2
GAS2
growth arrest-specific 2

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
1.8 10.9 GO:0051661 maintenance of centrosome location(GO:0051661)
1.6 4.9 GO:0006106 fumarate metabolic process(GO:0006106)
1.6 9.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
1.5 10.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.2 6.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
1.0 2.9 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.9 3.7 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.9 4.6 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.8 0.8 GO:0006533 aspartate catabolic process(GO:0006533)
0.8 5.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.6 3.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.6 2.3 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5 1.6 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5 5.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.5 1.4 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.4 3.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.4 3.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.4 1.5 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4 1.1 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3 7.3 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.3 1.7 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 4.6 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3 6.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 9.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.3 4.4 GO:0090168 Golgi reassembly(GO:0090168)
0.3 4.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3 3.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 1.5 GO:0071233 cellular response to leucine(GO:0071233)
0.2 5.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 5.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 6.2 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 3.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.2 12.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.2 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.2 0.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 5.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 3.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.2 4.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.1 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.9 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.6 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 2.7 GO:0060117 auditory receptor cell development(GO:0060117)
0.1 2.6 GO:0048311 mitochondrion distribution(GO:0048311)
0.1 2.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 2.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 0.5 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 1.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 3.1 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 5.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.4 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 3.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 2.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 6.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 8.5 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 2.3 GO:0015695 organic cation transport(GO:0015695)
0.1 2.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 2.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1 3.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 12.0 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 3.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.9 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.5 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 4.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 3.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.8 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 1.0 GO:0006629 lipid metabolic process(GO:0006629)
0.0 0.3 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 1.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 3.3 GO:0032886 regulation of microtubule-based process(GO:0032886)
0.0 1.4 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 2.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 10.9 GO:0036449 microtubule minus-end(GO:0036449)
1.5 6.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
1.5 10.5 GO:0044326 dendritic spine neck(GO:0044326)
1.3 15.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.6 7.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.6 5.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.5 1.6 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 1.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.4 4.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 5.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 5.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.4 1.1 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.3 4.9 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3 3.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 6.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 1.5 GO:0030891 VCB complex(GO:0030891)
0.2 5.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 1.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.2 1.3 GO:0045179 apical cortex(GO:0045179)
0.2 2.2 GO:0005833 hemoglobin complex(GO:0005833)
0.2 2.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.5 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 5.8 GO:0043034 costamere(GO:0043034)
0.1 4.0 GO:0016592 mediator complex(GO:0016592)
0.1 3.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 9.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.7 GO:0090544 BAF-type complex(GO:0090544)
0.1 2.7 GO:0032420 stereocilium(GO:0032420)
0.1 3.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 12.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.5 GO:0031105 septin complex(GO:0031105)
0.1 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 4.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 7.0 GO:0005814 centriole(GO:0005814)
0.1 3.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 4.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 11.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 6.9 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.4 GO:0036019 endolysosome(GO:0036019)
0.0 1.1 GO:0036126 sperm flagellum(GO:0036126)
0.0 2.1 GO:0042641 actomyosin(GO:0042641)
0.0 8.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 6.0 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.5 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 15.0 GO:0043515 kinetochore binding(GO:0043515)
2.2 6.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.2 3.5 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.0 3.1 GO:0070538 oleic acid binding(GO:0070538)
1.0 6.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.0 2.9 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.8 4.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.7 3.7 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.6 2.9 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.6 3.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.6 6.2 GO:0002151 G-quadruplex RNA binding(GO:0002151) RNA strand annealing activity(GO:0033592)
0.5 1.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 5.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.5 19.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.5 1.4 GO:0004947 bradykinin receptor activity(GO:0004947)
0.4 2.2 GO:0030492 hemoglobin binding(GO:0030492)
0.4 5.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 2.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 1.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 1.5 GO:0070728 leucine binding(GO:0070728)
0.3 6.5 GO:0000339 RNA cap binding(GO:0000339)
0.3 2.3 GO:0050692 DBD domain binding(GO:0050692)
0.3 3.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 10.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 5.2 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.3 4.6 GO:0043295 glutathione binding(GO:0043295)
0.3 1.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 4.1 GO:0008494 translation activator activity(GO:0008494)
0.2 7.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 12.0 GO:0019894 kinesin binding(GO:0019894)
0.2 2.3 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 6.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 3.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 2.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.9 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.6 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.1 0.5 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 3.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 3.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 15.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.3 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.7 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 10.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0030552 cAMP binding(GO:0030552)
0.0 3.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 2.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 4.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 4.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 5.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 3.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 4.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3 6.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 4.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 6.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 4.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 2.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 3.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 3.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 5.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 2.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 7.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 3.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 6.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 3.3 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 4.8 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 3.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 5.1 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.5 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions