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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MAFK

Z-value: 1.42

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Transcription factors associated with MAFK

Gene Symbol Gene ID Gene Info
ENSG00000198517.5 MAF bZIP transcription factor K

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFKhg19_v2_chr7_+_1570322_15703600.291.2e-05Click!

Activity profile of MAFK motif

Sorted Z-values of MAFK motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89459813 34.31 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr6_+_33043703 25.13 ENST00000418931.2
ENST00000535465.1
major histocompatibility complex, class II, DP beta 1
chr2_+_90060377 17.51 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr6_+_32709119 15.00 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr12_-_15103621 14.55 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr10_+_5135981 13.83 ENST00000380554.3
aldo-keto reductase family 1, member C3
chr3_-_121379739 13.62 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr22_+_23237555 12.93 ENST00000390321.2
immunoglobulin lambda constant 1 (Mcg marker)
chr1_+_158801095 12.47 ENST00000368141.4
myeloid cell nuclear differentiation antigen
chr12_+_69742121 12.34 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
lysozyme
chr22_+_23248512 12.05 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr2_-_89327228 11.86 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr2_-_89385283 11.75 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr1_+_117297007 11.48 ENST00000369478.3
ENST00000369477.1
CD2 molecule
chr2_+_89184868 11.04 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr2_-_89619904 10.89 ENST00000498574.1
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr2_+_89952792 10.38 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr4_+_69962212 10.18 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_-_71532339 10.02 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_-_106174960 9.67 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr4_+_69962185 9.60 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr13_-_46756351 9.58 ENST00000323076.2
lymphocyte cytosolic protein 1 (L-plastin)
chr15_-_20170354 9.58 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr4_+_70861647 9.48 ENST00000246895.4
ENST00000381060.2
statherin
chr10_-_5060201 9.21 ENST00000407674.1
aldo-keto reductase family 1, member C2
chr5_-_95158644 9.20 ENST00000237858.6
glutaredoxin (thioltransferase)
chr14_-_107114267 8.99 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr1_+_198608146 8.53 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr13_+_31309645 8.02 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chr1_-_169680745 8.01 ENST00000236147.4
selectin L
chr2_+_89999259 7.76 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr2_+_90211643 7.73 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr10_-_5060147 7.67 ENST00000604507.1
aldo-keto reductase family 1, member C2
chr1_-_158656488 7.64 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr11_-_5248294 7.54 ENST00000335295.4
hemoglobin, beta
chr2_-_89278535 7.20 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr3_+_122044084 7.09 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr13_-_46716969 7.08 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_106518922 7.03 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr14_-_106994333 6.91 ENST00000390624.2
immunoglobulin heavy variable 3-48
chr14_-_106963409 6.89 ENST00000390621.2
immunoglobulin heavy variable 1-45
chr2_+_89890533 6.88 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chrX_+_128913906 6.87 ENST00000356892.3
SAM and SH3 domain containing 3
chr6_-_52628271 6.76 ENST00000493422.1
glutathione S-transferase alpha 2
chr6_+_6588316 6.61 ENST00000379953.2
lymphocyte antigen 86
chr2_+_90153696 6.61 ENST00000417279.2
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr11_+_57365150 6.57 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chrY_+_2709527 6.56 ENST00000250784.8
ribosomal protein S4, Y-linked 1
chr14_+_21423611 6.56 ENST00000304625.2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr2_-_89247338 6.36 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr6_-_49712147 6.31 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr19_-_54784937 6.22 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr2_+_89998789 6.22 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr5_+_54398463 6.15 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr4_+_74275057 6.13 ENST00000511370.1
albumin
chr2_+_90458201 6.11 ENST00000603238.1
Uncharacterized protein
chr6_-_25042231 6.07 ENST00000510784.2
family with sequence similarity 65, member B
chr2_+_89975669 5.83 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chrX_-_107018969 5.80 ENST00000372383.4
TSC22 domain family, member 3
chr11_-_85376121 5.76 ENST00000527447.1
CREB/ATF bZIP transcription factor
chr1_-_89591749 5.73 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr6_+_32812568 5.71 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr17_-_42327236 5.70 ENST00000399246.2
AC003102.1
chr4_+_102734967 5.67 ENST00000444316.2
B-cell scaffold protein with ankyrin repeats 1
chr4_-_100212132 5.65 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr14_-_106692191 5.53 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr14_-_106967788 5.47 ENST00000390622.2
immunoglobulin heavy variable 1-46
chr11_+_60223225 5.45 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr7_+_150264365 5.45 ENST00000255945.2
ENST00000461940.1
GTPase, IMAP family member 4
chr16_+_33020496 5.36 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr1_-_153113927 5.29 ENST00000368752.4
small proline-rich protein 2B
chr9_-_137809718 5.29 ENST00000371806.3
ficolin (collagen/fibrinogen domain containing) 1
chr12_+_51318513 5.29 ENST00000332160.4
methyltransferase like 7A
chr8_-_134072593 5.27 ENST00000427060.2
Src-like-adaptor
chr1_+_26856236 5.22 ENST00000374168.2
ENST00000374166.4
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr10_+_5005445 5.11 ENST00000380872.4
aldo-keto reductase family 1, member C1
chr4_-_70080449 5.10 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chr11_-_62752162 4.99 ENST00000458333.2
ENST00000421062.2
solute carrier family 22 (organic anion transporter), member 6
chr7_+_50344289 4.98 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKAROS family zinc finger 1 (Ikaros)
chr4_+_70146217 4.95 ENST00000335568.5
ENST00000511240.1
UDP glucuronosyltransferase 2 family, polypeptide B28
chr9_-_5833027 4.84 ENST00000339450.5
endoplasmic reticulum metallopeptidase 1
chr17_-_64216748 4.82 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_207095324 4.81 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr10_-_5046042 4.74 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr21_+_10862622 4.71 ENST00000302092.5
ENST00000559480.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr7_+_139528952 4.66 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr14_-_106866934 4.62 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr6_-_49712123 4.57 ENST00000263045.4
cysteine-rich secretory protein 3
chr2_-_231090344 4.51 ENST00000540870.1
ENST00000416610.1
SP110 nuclear body protein
chr12_-_10282836 4.51 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr14_-_75593708 4.44 ENST00000557673.1
ENST00000238616.5
NIMA-related kinase 9
chr1_-_47407136 4.44 ENST00000462347.1
ENST00000371905.1
ENST00000310638.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chrX_+_123480194 4.42 ENST00000371139.4
SH2 domain containing 1A
chr14_-_107078851 4.37 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr14_-_106610852 4.37 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr1_+_111682058 4.37 ENST00000545121.1
choline/ethanolamine phosphotransferase 1
chr12_+_56435637 4.36 ENST00000356464.5
ENST00000552361.1
ribosomal protein S26
chr7_+_80267973 4.35 ENST00000394788.3
ENST00000447544.2
CD36 molecule (thrombospondin receptor)
chr4_+_69681710 4.34 ENST00000265403.7
ENST00000458688.2
UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_+_54359854 4.34 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
deiodinase, iodothyronine, type I
chr3_+_111260954 4.34 ENST00000283285.5
CD96 molecule
chr11_+_63304273 4.31 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr8_+_1993152 4.29 ENST00000262113.4
myomesin 2
chr12_-_71533055 4.25 ENST00000552128.1
tetraspanin 8
chr19_-_54876414 4.25 ENST00000474878.1
ENST00000348231.4
leukocyte-associated immunoglobulin-like receptor 1
chr2_-_89568263 4.22 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr14_-_106725723 4.20 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr7_+_139529040 4.20 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr6_+_31582961 4.16 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr12_-_7656357 4.16 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163 molecule
chr1_+_119911425 4.13 ENST00000361035.4
ENST00000325945.3
hydroxyacid oxidase 2 (long chain)
chrY_+_22737678 4.06 ENST00000382772.3
eukaryotic translation initiation factor 1A, Y-linked
chr18_+_21693306 4.06 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr11_+_65647280 4.04 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
cathepsin W
chr2_-_89521942 4.04 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr2_+_234959323 3.99 ENST00000373368.1
ENST00000168148.3
secreted phosphoprotein 2, 24kDa
chr2_+_8822113 3.99 ENST00000396290.1
ENST00000331129.3
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr6_-_52668605 3.97 ENST00000334575.5
glutathione S-transferase alpha 1
chr14_-_106573756 3.97 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr21_+_39628852 3.88 ENST00000398938.2
potassium inwardly-rectifying channel, subfamily J, member 15
chr18_+_29171689 3.85 ENST00000237014.3
transthyretin
chr3_+_186383741 3.83 ENST00000232003.4
histidine-rich glycoprotein
chr3_+_186330712 3.81 ENST00000411641.2
ENST00000273784.5
alpha-2-HS-glycoprotein
chr1_+_158978768 3.80 ENST00000447473.2
interferon, gamma-inducible protein 16
chr5_+_156696362 3.77 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr17_-_76124711 3.77 ENST00000306591.7
ENST00000590602.1
transmembrane channel-like 6
chr1_-_12677714 3.76 ENST00000376223.2
dehydrogenase/reductase (SDR family) member 3
chr2_+_203499901 3.75 ENST00000303116.6
ENST00000392238.2
family with sequence similarity 117, member B
chrX_+_153627231 3.74 ENST00000406022.2
ribosomal protein L10
chr4_-_100356291 3.70 ENST00000476959.1
ENST00000482593.1
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_59633951 3.69 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr2_+_231090433 3.67 ENST00000486687.2
ENST00000350136.5
ENST00000392045.3
ENST00000417495.3
ENST00000343805.6
ENST00000420434.3
SP140 nuclear body protein
chr14_+_22919081 3.66 ENST00000390473.1
T cell receptor delta joining 1
chr1_+_153004800 3.62 ENST00000392661.3
small proline-rich protein 1B
chr22_+_21133469 3.61 ENST00000406799.1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr10_+_51576285 3.60 ENST00000443446.1
nuclear receptor coactivator 4
chr11_-_6462210 3.60 ENST00000265983.3
hemopexin
chr17_-_19648683 3.58 ENST00000573368.1
ENST00000457500.2
aldehyde dehydrogenase 3 family, member A1
chr8_+_27168988 3.57 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
protein tyrosine kinase 2 beta
chr4_-_46911248 3.57 ENST00000355591.3
ENST00000505102.1
cytochrome c oxidase subunit VIIb2
chr1_+_171217622 3.52 ENST00000433267.1
ENST00000367750.3
flavin containing monooxygenase 1
chr19_-_10491234 3.51 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
tyrosine kinase 2
chr5_+_54320078 3.51 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr11_-_57335750 3.48 ENST00000340573.4
ubiquitin-conjugating enzyme E2L 6
chr11_-_114466477 3.46 ENST00000375478.3
neurexophilin and PC-esterase domain family, member 4
chr16_+_30211181 3.45 ENST00000395138.2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr19_+_42388437 3.42 ENST00000378152.4
ENST00000337665.4
Rho guanine nucleotide exchange factor (GEF) 1
chr9_-_116840728 3.41 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr8_+_94241867 3.40 ENST00000598428.1
Uncharacterized protein
chr1_+_104198377 3.40 ENST00000370083.4
amylase, alpha 1A (salivary)
chr3_+_111260856 3.39 ENST00000352690.4
CD96 molecule
chr6_+_42584847 3.37 ENST00000372883.3
ubiquitin protein ligase E3 component n-recognin 2
chrY_+_22737604 3.36 ENST00000361365.2
eukaryotic translation initiation factor 1A, Y-linked
chr6_+_131894284 3.35 ENST00000368087.3
ENST00000356962.2
arginase 1
chr14_-_106878083 3.33 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr9_-_116837249 3.33 ENST00000466610.2
alpha-1-microglobulin/bikunin precursor
chr2_+_114163945 3.29 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr17_+_56315936 3.25 ENST00000543544.1
lactoperoxidase
chr14_-_23426322 3.25 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr14_-_23426270 3.24 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr8_+_1993173 3.22 ENST00000523438.1
myomesin 2
chr21_+_39628655 3.22 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr10_+_73079000 3.22 ENST00000373189.5
solute carrier family 29 (equilibrative nucleoside transporter), member 3
chr11_-_58345569 3.21 ENST00000528954.1
ENST00000528489.1
leupaxin
chr11_-_104817919 3.19 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr16_+_32077386 3.19 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr9_-_123676827 3.18 ENST00000546084.1
TNF receptor-associated factor 1
chr13_-_99959641 3.17 ENST00000376414.4
G protein-coupled receptor 183
chr1_+_6640108 3.17 ENST00000377674.4
ENST00000488936.1
zinc finger and BTB domain containing 48
chr13_-_107220455 3.16 ENST00000400198.3
arginine and glutamate rich 1
chr4_-_48082192 3.14 ENST00000507351.1
TXK tyrosine kinase
chr1_-_207095212 3.13 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr5_+_140207536 3.13 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr6_-_41909561 3.07 ENST00000372991.4
cyclin D3
chr14_-_23426337 3.07 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr1_-_146054494 3.06 ENST00000401009.2
neuroblastoma breakpoint family, member 11
chr7_-_36764004 3.05 ENST00000431169.1
acyloxyacyl hydrolase (neutrophil)
chr11_-_57283159 3.03 ENST00000533263.1
ENST00000278426.3
solute carrier family 43 (amino acid system L transporter), member 1
chr7_-_36634181 3.02 ENST00000538464.1
acyloxyacyl hydrolase (neutrophil)
chr12_+_10460549 3.02 ENST00000543420.1
ENST00000543777.1
killer cell lectin-like receptor subfamily D, member 1
chr22_+_23154239 3.01 ENST00000390315.2
immunoglobulin lambda variable 3-10
chr17_-_76124812 3.00 ENST00000592063.1
ENST00000589271.1
ENST00000322933.4
ENST00000589553.1
transmembrane channel-like 6
chr1_+_43291220 3.00 ENST00000372514.3
erythroblast membrane-associated protein (Scianna blood group)
chr1_+_90460661 2.97 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
zinc finger protein 326
chr13_-_99910673 2.96 ENST00000397473.2
ENST00000397470.2
G protein-coupled receptor 18
chr9_-_95640218 2.95 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
zinc finger protein 484
chr16_+_32063311 2.95 ENST00000426099.1
AC142381.1
chr16_-_67970990 2.95 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr17_+_56315787 2.95 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr2_+_234602305 2.94 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr14_+_20937538 2.94 ENST00000361505.5
ENST00000553591.1
purine nucleoside phosphorylase
chr4_-_110723194 2.93 ENST00000394635.3
complement factor I
chrX_+_153626708 2.92 ENST00000436473.1
ENST00000344746.4
ENST00000458500.1
ribosomal protein L10
chr2_-_43823119 2.92 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
thyroid adenoma associated
chr17_-_62084241 2.91 ENST00000449662.2
intercellular adhesion molecule 2
chr2_-_43823093 2.87 ENST00000405006.4
thyroid adenoma associated
chr12_-_113772835 2.84 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr11_+_116700600 2.81 ENST00000227667.3
apolipoprotein C-III
chr11_+_118175132 2.80 ENST00000361763.4
CD3e molecule, epsilon (CD3-TCR complex)
chr9_-_95244781 2.79 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFK

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 42.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
3.6 14.5 GO:0071461 cellular response to redox state(GO:0071461)
2.6 7.7 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
2.5 12.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
2.3 2.3 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
2.3 6.8 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
2.0 4.0 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
1.9 7.8 GO:0003095 pressure natriuresis(GO:0003095)
1.9 11.5 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
1.9 7.5 GO:0030185 nitric oxide transport(GO:0030185)
1.8 5.3 GO:0060621 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.8 5.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.7 8.5 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
1.7 6.7 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.7 5.0 GO:0097254 renal tubular secretion(GO:0097254)
1.6 4.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.6 6.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
1.5 1.5 GO:0006711 estrogen catabolic process(GO:0006711)
1.5 222.1 GO:0006958 complement activation, classical pathway(GO:0006958)
1.5 4.4 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
1.4 5.8 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.2 6.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.2 3.6 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
1.2 9.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.2 26.5 GO:0052695 cellular glucuronidation(GO:0052695)
1.1 3.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.1 5.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
1.1 9.5 GO:0046541 saliva secretion(GO:0046541)
1.0 16.7 GO:0051639 actin filament network formation(GO:0051639)
1.0 2.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.0 6.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
1.0 12.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.0 2.9 GO:0070637 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
1.0 3.8 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.9 2.8 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.9 2.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.9 2.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.9 0.9 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.9 8.0 GO:2001300 lipoxin metabolic process(GO:2001300)
0.9 6.2 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.9 3.6 GO:0035995 detection of muscle stretch(GO:0035995)
0.8 4.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.8 5.8 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8 3.3 GO:0007525 somatic muscle development(GO:0007525)
0.8 6.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.8 4.9 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.8 5.6 GO:0006069 ethanol oxidation(GO:0006069)
0.8 13.6 GO:0045651 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of macrophage differentiation(GO:0045651)
0.8 2.3 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.7 6.7 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.7 5.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.7 2.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.7 2.2 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.7 2.2 GO:0051697 protein delipidation(GO:0051697)
0.7 2.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.7 2.1 GO:1903969 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) regulation of response to macrophage colony-stimulating factor(GO:1903969) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.7 6.2 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.7 5.4 GO:0070995 NADPH oxidation(GO:0070995)
0.7 6.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.7 3.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.7 2.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.7 3.3 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.7 2.0 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.6 2.6 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.6 0.6 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.6 0.6 GO:0016569 covalent chromatin modification(GO:0016569)
0.6 14.6 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.6 3.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.6 1.9 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.6 4.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.6 1.8 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.6 6.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.6 1.8 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.6 3.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.6 87.4 GO:0002377 immunoglobulin production(GO:0002377)
0.6 1.2 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.6 1.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6 3.4 GO:0071233 cellular response to leucine(GO:0071233)
0.6 2.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.5 0.5 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.5 3.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.5 3.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 8.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 3.6 GO:0008218 bioluminescence(GO:0008218)
0.5 3.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.5 2.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.5 2.0 GO:0048807 ectoderm and mesoderm interaction(GO:0007499) female genitalia morphogenesis(GO:0048807)
0.5 3.4 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.5 2.4 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.5 2.4 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.5 1.4 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.5 3.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 3.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 2.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.5 0.9 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.5 2.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.4 5.8 GO:0042832 defense response to protozoan(GO:0042832)
0.4 3.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 1.3 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.4 3.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.4 1.7 GO:0072553 terminal button organization(GO:0072553)
0.4 1.7 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.4 7.6 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.4 2.5 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.4 24.6 GO:0018149 peptide cross-linking(GO:0018149)
0.4 4.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.4 3.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4 2.8 GO:0002118 aggressive behavior(GO:0002118)
0.4 11.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.4 40.4 GO:0031295 T cell costimulation(GO:0031295)
0.4 2.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 1.2 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.4 2.3 GO:0001781 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.4 1.5 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.4 1.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619) positive regulation of sarcomere organization(GO:0060298)
0.4 4.2 GO:0006824 cobalt ion transport(GO:0006824)
0.4 4.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.4 1.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.4 3.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 0.7 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.4 1.1 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) membrane depolarization during bundle of His cell action potential(GO:0086048)
0.4 1.1 GO:0035900 response to isolation stress(GO:0035900)
0.4 3.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 1.4 GO:0042320 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) negative regulation of urine volume(GO:0035811) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.3 2.0 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.3 9.1 GO:0042572 retinol metabolic process(GO:0042572)
0.3 3.0 GO:0015886 heme transport(GO:0015886)
0.3 1.0 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.3 6.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.3 2.0 GO:0070383 DNA cytosine deamination(GO:0070383)
0.3 1.6 GO:0006574 valine catabolic process(GO:0006574)
0.3 1.3 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.3 2.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.3 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3 1.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 5.9 GO:0005513 detection of calcium ion(GO:0005513)
0.3 3.8 GO:0018065 protein-cofactor linkage(GO:0018065)
0.3 0.6 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.3 2.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3 0.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.3 1.5 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 4.5 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.3 1.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.3 10.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 2.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.3 2.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 1.9 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.3 1.1 GO:0070627 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 1.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 0.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 2.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 2.7 GO:0032264 IMP salvage(GO:0032264)
0.3 2.1 GO:0015705 iodide transport(GO:0015705)
0.3 4.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.3 1.3 GO:0034201 response to oleic acid(GO:0034201)
0.3 3.3 GO:0031268 pseudopodium organization(GO:0031268)
0.3 7.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 1.0 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.3 2.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.3 0.8 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.2 5.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.2 4.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 0.7 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.2 0.7 GO:1904404 response to vitamin B1(GO:0010266) cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 1.9 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.9 GO:0002252 immune effector process(GO:0002252)
0.2 4.4 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.7 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.1 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 1.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 10.7 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.2 0.4 GO:0006956 complement activation(GO:0006956)
0.2 9.0 GO:0010107 potassium ion import(GO:0010107)
0.2 0.8 GO:0010002 cardioblast differentiation(GO:0010002)
0.2 1.8 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.4 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.2 1.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.2 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.2 2.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.2 GO:0016925 protein sumoylation(GO:0016925)
0.2 1.9 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.2 2.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 1.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.2 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 2.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2 3.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 1.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.2 24.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 1.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 2.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 1.3 GO:0032790 ribosome disassembly(GO:0032790)
0.2 2.4 GO:0006449 regulation of translational termination(GO:0006449)
0.2 4.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.2 2.6 GO:0019835 cytolysis(GO:0019835)
0.2 1.8 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 5.0 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.1 0.7 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.4 GO:0051685 maintenance of ER location(GO:0051685)
0.1 1.7 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 1.6 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 2.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.0 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.6 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.4 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 1.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 4.8 GO:0033198 response to ATP(GO:0033198)
0.1 1.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.8 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 2.2 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 1.7 GO:0097186 amelogenesis(GO:0097186)
0.1 1.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 2.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 2.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.9 GO:0010506 regulation of autophagy(GO:0010506)
0.1 0.7 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1 1.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.4 GO:0015074 DNA integration(GO:0015074)
0.1 1.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 1.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.4 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.2 GO:0003285 septum secundum development(GO:0003285)
0.1 3.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.7 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 1.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.3 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 2.0 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.4 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.1 1.0 GO:0000733 DNA strand renaturation(GO:0000733) t-circle formation(GO:0090656)
0.1 1.0 GO:0006600 creatine metabolic process(GO:0006600)
0.1 5.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 1.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 2.0 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 1.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 1.3 GO:0006068 ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.1 4.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.4 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 1.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 1.0 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.9 GO:0042100 B cell proliferation(GO:0042100)
0.1 1.1 GO:0006465 signal peptide processing(GO:0006465)
0.1 3.2 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 0.9 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 2.0 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 4.2 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.9 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 0.2 GO:0042737 drug catabolic process(GO:0042737)
0.1 1.0 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 2.0 GO:0050832 defense response to fungus(GO:0050832)
0.1 0.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 4.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 7.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 2.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 4.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.7 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 1.3 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.3 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 0.3 GO:1990481 tRNA pseudouridine synthesis(GO:0031119) mRNA pseudouridine synthesis(GO:1990481)
0.1 0.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.4 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.4 GO:0071104 response to interleukin-9(GO:0071104)
0.1 2.9 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.7 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.1 0.8 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.1 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.7 GO:0051923 sulfation(GO:0051923)
0.1 7.4 GO:0006413 translational initiation(GO:0006413)
0.1 2.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.4 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.8 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 5.0 GO:0030218 erythrocyte differentiation(GO:0030218)
0.1 0.6 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 2.4 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.4 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.1 1.3 GO:0097484 dendrite extension(GO:0097484)
0.1 0.9 GO:0017156 synaptic vesicle exocytosis(GO:0016079) calcium ion regulated exocytosis(GO:0017156)
0.1 0.8 GO:0046688 response to copper ion(GO:0046688)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.6 GO:0070875 positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.2 GO:0021983 pituitary gland development(GO:0021983)
0.0 1.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098) calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.9 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 1.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.9 GO:0051646 mitochondrion localization(GO:0051646)
0.0 1.3 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 1.7 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 1.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.2 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 2.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.9 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0008272 sulfate transport(GO:0008272)
0.0 0.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.1 GO:0001947 heart looping(GO:0001947)
0.0 1.0 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099) citrate metabolic process(GO:0006101)
0.0 0.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.0 1.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.6 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 1.3 GO:0006826 iron ion transport(GO:0006826)
0.0 3.5 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.4 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.1 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 1.4 GO:0071222 cellular response to lipopolysaccharide(GO:0071222)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.7 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.6 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.8 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 0.1 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.8 GO:0042303 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.9 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.4 GO:0046849 bone remodeling(GO:0046849)
0.0 1.0 GO:0007586 digestion(GO:0007586)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0001895 retina homeostasis(GO:0001895)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
2.0 42.2 GO:0042613 MHC class II protein complex(GO:0042613)
1.9 7.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.5 71.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.5 4.4 GO:0061673 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
1.1 20.8 GO:0001891 phagocytic cup(GO:0001891)
1.1 7.6 GO:0032437 cuticular plate(GO:0032437)
1.1 8.7 GO:1990111 spermatoproteasome complex(GO:1990111)
1.1 6.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.1 9.6 GO:0070652 HAUS complex(GO:0070652)
1.0 3.0 GO:0044609 DBIRD complex(GO:0044609)
1.0 5.9 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.9 5.3 GO:0034366 intermediate-density lipoprotein particle(GO:0034363) spherical high-density lipoprotein particle(GO:0034366)
0.8 5.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.8 14.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.8 134.4 GO:0072562 blood microparticle(GO:0072562)
0.6 3.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.6 1.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.6 1.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.6 1.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.5 13.1 GO:0032982 myosin filament(GO:0032982)
0.5 2.5 GO:0005579 membrane attack complex(GO:0005579)
0.5 4.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.4 41.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.4 1.9 GO:0000801 central element(GO:0000801)
0.4 5.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 1.7 GO:0071546 pi-body(GO:0071546)
0.3 3.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 0.9 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 4.3 GO:0036038 MKS complex(GO:0036038)
0.3 16.1 GO:0001533 cornified envelope(GO:0001533)
0.3 1.2 GO:0030314 junctional membrane complex(GO:0030314)
0.3 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 4.8 GO:0005859 muscle myosin complex(GO:0005859)
0.3 20.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 3.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 1.3 GO:0070826 paraferritin complex(GO:0070826)
0.3 3.6 GO:0044754 autolysosome(GO:0044754)
0.3 1.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.3 2.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 4.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 3.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 3.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 7.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 13.5 GO:0035580 specific granule lumen(GO:0035580)
0.2 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 1.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 2.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 2.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 2.0 GO:0044327 dendritic spine head(GO:0044327)
0.2 2.9 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 0.6 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.1 GO:0005787 signal peptidase complex(GO:0005787)
0.1 6.1 GO:0002102 podosome(GO:0002102)
0.1 37.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.6 GO:0000811 GINS complex(GO:0000811)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 14.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 3.5 GO:0031143 pseudopodium(GO:0031143)
0.1 1.0 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 2.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.7 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 5.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 2.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.8 GO:0001740 Barr body(GO:0001740)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 3.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 2.0 GO:0031902 late endosome membrane(GO:0031902)
0.1 3.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.3 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 3.6 GO:0005902 microvillus(GO:0005902)
0.1 104.7 GO:0005615 extracellular space(GO:0005615)
0.1 5.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 1.7 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 2.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.6 GO:0000791 euchromatin(GO:0000791)
0.1 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 2.3 GO:0016459 myosin complex(GO:0016459)
0.1 5.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.7 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 3.5 GO:0016605 PML body(GO:0016605)
0.0 3.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 2.4 GO:0030426 growth cone(GO:0030426)
0.0 1.3 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 5.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.0 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 40.6 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
3.4 10.3 GO:0046848 hydroxyapatite binding(GO:0046848)
3.0 8.9 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
2.8 8.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
2.7 8.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
2.1 12.3 GO:0003796 lysozyme activity(GO:0003796)
1.9 7.8 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.7 10.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.6 1.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.6 6.2 GO:0023029 MHC class Ib protein binding(GO:0023029)
1.6 6.2 GO:0019862 IgA binding(GO:0019862)
1.5 4.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
1.5 81.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.5 14.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.3 6.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.3 227.3 GO:0003823 antigen binding(GO:0003823)
1.3 5.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.3 6.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
1.3 4.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.3 18.2 GO:0032395 MHC class II receptor activity(GO:0032395)
1.3 7.5 GO:0030492 hemoglobin binding(GO:0030492)
1.2 3.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.2 11.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.1 8.0 GO:0043208 glycosphingolipid binding(GO:0043208)
1.1 6.6 GO:0004522 ribonuclease A activity(GO:0004522)
1.1 4.4 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
1.0 2.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.9 2.7 GO:0097001 ceramide binding(GO:0097001)
0.9 2.6 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.9 33.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.9 2.6 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.8 3.4 GO:0016160 amylase activity(GO:0016160)
0.8 2.4 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.8 2.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.7 2.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.7 4.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.7 2.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.7 3.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.7 2.1 GO:0097677 STAT family protein binding(GO:0097677)
0.7 6.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.7 2.0 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.7 6.6 GO:0015232 heme transporter activity(GO:0015232)
0.7 3.3 GO:0070728 leucine binding(GO:0070728)
0.7 2.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.6 5.8 GO:0043426 MRF binding(GO:0043426)
0.6 3.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 3.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.6 5.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 3.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.6 13.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.6 3.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.6 3.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.6 5.7 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.6 6.7 GO:0033691 sialic acid binding(GO:0033691)
0.5 1.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.5 2.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 1.5 GO:0005174 CD40 receptor binding(GO:0005174)
0.5 1.9 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.5 6.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.5 3.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 2.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.5 1.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.5 2.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.5 2.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.5 3.2 GO:0008142 oxysterol binding(GO:0008142)
0.4 1.8 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.4 4.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.4 8.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 2.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 4.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.4 1.3 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.4 1.7 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.4 5.8 GO:0050700 CARD domain binding(GO:0050700)
0.4 2.8 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.4 2.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.4 2.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.4 3.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.4 2.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.4 1.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.4 6.1 GO:0015643 toxic substance binding(GO:0015643)
0.4 1.9 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.4 3.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 1.1 GO:0005549 odorant binding(GO:0005549)
0.4 1.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 1.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.4 2.9 GO:0004064 arylesterase activity(GO:0004064)
0.4 1.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4 1.5 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.4 1.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.4 1.8 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.4 2.5 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 1.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 0.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.3 2.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.3 2.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 25.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 0.9 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 2.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 3.5 GO:0005131 growth hormone receptor binding(GO:0005131)
0.3 1.7 GO:0004447 iodide peroxidase activity(GO:0004447)
0.3 1.7 GO:0089720 caspase binding(GO:0089720)
0.3 2.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 1.4 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 5.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.3 1.3 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 2.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.0 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.2 1.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 3.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.7 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 2.8 GO:0042608 T cell receptor binding(GO:0042608)
0.2 2.1 GO:0031433 telethonin binding(GO:0031433)
0.2 3.7 GO:0019864 IgG binding(GO:0019864)
0.2 1.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 1.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 3.2 GO:0031996 thioesterase binding(GO:0031996)
0.2 3.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 0.6 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 1.0 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.2 1.0 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 4.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 0.6 GO:0043398 HLH domain binding(GO:0043398)
0.2 2.3 GO:0070064 proline-rich region binding(GO:0070064)
0.2 0.6 GO:0001847 opsonin receptor activity(GO:0001847)
0.2 0.6 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 2.1 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.8 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 2.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 5.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 4.6 GO:0031489 myosin V binding(GO:0031489)
0.2 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.7 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 4.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.0 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.2 3.0 GO:0070403 NAD+ binding(GO:0070403)
0.2 4.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.9 GO:0043532 angiostatin binding(GO:0043532)
0.2 1.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 3.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.4 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 2.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 2.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 3.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 3.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0004040 amidase activity(GO:0004040)
0.1 3.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 2.1 GO:0005522 profilin binding(GO:0005522)
0.1 2.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.2 GO:0016918 retinal binding(GO:0016918)
0.1 1.0 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.0 GO:0000182 rDNA binding(GO:0000182)
0.1 4.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 2.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.5 GO:0004601 peroxidase activity(GO:0004601)
0.1 4.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 11.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.5 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 4.3 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.1 14.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 2.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 6.9 GO:0019843 rRNA binding(GO:0019843)
0.1 21.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.8 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 6.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 1.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 16.2 GO:0051015 actin filament binding(GO:0051015)
0.1 1.3 GO:0008494 translation activator activity(GO:0008494)
0.1 1.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 6.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 3.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 12.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 5.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 5.0 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 3.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 5.3 GO:0005518 collagen binding(GO:0005518)
0.1 3.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 2.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 8.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 1.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.0 GO:0008483 transaminase activity(GO:0008483)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.9 GO:0030276 clathrin binding(GO:0030276)
0.0 5.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 9.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.4 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.0 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 1.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) D1 dopamine receptor binding(GO:0031748)
0.0 0.9 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 3.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 9.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 17.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 2.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 11.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 7.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 1.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 3.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 8.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 11.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 11.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 6.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 5.4 PID BCR 5PATHWAY BCR signaling pathway
0.1 25.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 17.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.8 PID BMP PATHWAY BMP receptor signaling
0.1 10.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.1 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 6.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 6.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.7 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 6.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 0.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 5.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 5.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 4.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 4.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 53.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.7 44.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.3 10.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.0 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5 8.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.5 11.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 34.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 8.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 3.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 19.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.3 9.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 2.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 3.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 6.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 18.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 5.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 3.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 1.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 4.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 5.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 2.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 3.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 2.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 17.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 7.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 6.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 6.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 11.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 17.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 4.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 2.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 0.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 1.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 8.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.4 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 1.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 4.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 5.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 17.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 9.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 4.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 2.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.3 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 2.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.6 REACTOME OPSINS Genes involved in Opsins
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 4.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.6 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 5.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling