averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
MAX Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000125952.14	MYC associated factor X
TFEB Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000112561.13	transcription factor EB

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TFEB	hg19_v2_chr6_-_41701581_41701613	-0.76	7.3e-43	Click!
MAX	hg19_v2_chr14_-_65569186_65569243	0.38	5.9e-09	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_58146128 Show fit	303.08	ENST00000551800.1 ENST00000549606.1 ENST00000257904.6	CDK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 4
chr12_-_58146048 Show fit	295.02	ENST00000547281.1 ENST00000546489.1 ENST00000552388.1 ENST00000540325.1 ENST00000312990.6	CDK4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 4
chr4_-_100871506 Show fit	104.28	ENST00000296417.5	H2AFZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H2A histone family, member Z
chr8_+_98656336 Show fit	95.75	ENST00000336273.3	MTDH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	metadherin
chr2_+_216176540 Show fit	89.25	ENST00000236959.9	ATIC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_-_109703600 Show fit	88.98	ENST00000512821.1	CD164 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD164 molecule, sialomucin
chr20_+_44520009 Show fit	85.04	ENST00000607482.1 ENST00000372459.2	CTSA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cathepsin A
chr20_+_44519948 Show fit	81.98	ENST00000354880.5 ENST00000191018.5	CTSA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cathepsin A
chr6_-_33385854 Show fit	81.60	ENST00000488478.1	CUTA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr2_+_216176761 Show fit	80.64	ENST00000540518.1 ENST00000435675.1	ATIC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr4_-_99850243 Show fit	80.55	ENST00000280892.6 ENST00000511644.1 ENST00000504432.1 ENST00000505992.1	EIF4E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 4E
chr1_+_44440575 Show fit	80.41	ENST00000532642.1 ENST00000236067.4 ENST00000471859.2	ATP6V0B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr4_-_47465666 Show fit	78.60	ENST00000381571.4	COMMD8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 8
chr2_-_10587897 Show fit	76.21	ENST00000405333.1 ENST00000443218.1	ODC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ornithine decarboxylase 1
chr19_+_5681153 Show fit	71.74	ENST00000579559.1 ENST00000577222.1	HSD11B1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit RPL36 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (11-beta) dehydrogenase 1-like ribosomal protein L36
chrX_-_100662881 Show fit	70.74	ENST00000218516.3	GLA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	galactosidase, alpha
chr14_+_20923350 Show fit	66.08	ENST00000555414.1 ENST00000216714.3 ENST00000553681.1 ENST00000557344.1 ENST00000398030.4 ENST00000557181.1 ENST00000555839.1 ENST00000553368.1 ENST00000556054.1 ENST00000557054.1 ENST00000557592.1 ENST00000557150.1	APEX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	APEX nuclease (multifunctional DNA repair enzyme) 1
chr3_+_158519654 Show fit	65.50	ENST00000415822.2 ENST00000392813.4 ENST00000264266.8	MFSD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major facilitator superfamily domain containing 1
chr6_-_33385655 Show fit	64.53	ENST00000440279.3 ENST00000607266.1	CUTA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr6_-_109703663 Show fit	61.35	ENST00000368961.5	CD164 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD164 molecule, sialomucin
chr8_+_98656693 Show fit	60.68	ENST00000519934.1	MTDH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	metadherin
chr1_-_183604794 Show fit	58.47	ENST00000367534.1 ENST00000359856.6 ENST00000294742.6	ARPC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 5, 16kDa
chr6_+_160390102 Show fit	57.23	ENST00000356956.1	IGF2R Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 receptor
chr12_-_2986107 Show fit	57.17	ENST00000359843.3 ENST00000342628.2 ENST00000361953.3	FOXM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	forkhead box M1
chr6_-_33385823 Show fit	56.19	ENST00000494751.1 ENST00000374496.3	CUTA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr1_+_33116765 Show fit	54.97	ENST00000544435.1 ENST00000373485.1 ENST00000458695.2 ENST00000490500.1 ENST00000445722.2	RBBP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoblastoma binding protein 4
chr17_-_46688334 Show fit	54.87	ENST00000239165.7	HOXB7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox B7
chr19_+_8509842 Show fit	54.26	ENST00000325495.4 ENST00000600092.1 ENST00000594907.1 ENST00000596984.1 ENST00000601645.1	HNRNPM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein M
chr5_+_65440032 Show fit	54.22	ENST00000334121.6	SREK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	splicing regulatory glutamine/lysine-rich protein 1
chr9_-_34048873 Show fit	51.92	ENST00000449054.1 ENST00000379239.4 ENST00000539807.1 ENST00000379238.1 ENST00000418786.2 ENST00000360802.1 ENST00000412543.1	UBAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin associated protein 2
chr11_-_64014379 Show fit	51.55	ENST00000309318.3	PPP1R14B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr10_-_120840309 Show fit	50.34	ENST00000369144.3	EIF3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit A
chr12_-_56709786 Show fit	49.98	ENST00000547423.1 ENST00000548360.1 ENST00000551475.1	RP11-977G19.10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit CNPY2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein canopy FGF signaling regulator 2
chrX_+_23685653 Show fit	48.81	ENST00000379331.3	PRDX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxiredoxin 4
chr6_-_33385870 Show fit	48.34	ENST00000488034.1	CUTA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr12_+_56110247 Show fit	48.13	ENST00000551926.1	BLOC1S1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	biogenesis of lysosomal organelles complex-1, subunit 1
chr21_-_46237883 Show fit	47.70	ENST00000397893.3	SUMO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 3
chr3_+_127317066 Show fit	47.48	ENST00000265056.7	MCM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 2
chr1_+_33116743 Show fit	46.47	ENST00000414241.3 ENST00000373493.5	RBBP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoblastoma binding protein 4
chr19_+_47634039 Show fit	46.44	ENST00000597808.1 ENST00000413379.3 ENST00000600706.1 ENST00000540850.1 ENST00000598840.1 ENST00000600753.1 ENST00000270225.7 ENST00000392776.3	SAE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SUMO1 activating enzyme subunit 1
chr10_+_51827648 Show fit	46.44	ENST00000351071.6 ENST00000314664.7 ENST00000282633.5	FAM21A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 21, member A
chr5_+_110074685 Show fit	45.72	ENST00000355943.3 ENST00000447245.2	SLC25A46 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25, member 46
chr6_-_109703634 Show fit	45.48	ENST00000324953.5 ENST00000310786.4 ENST00000275080.7 ENST00000413644.2	CD164 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD164 molecule, sialomucin
chr11_-_47664072 Show fit	45.11	ENST00000542981.1 ENST00000530428.1 ENST00000302503.3	MTCH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial carrier 2
chr12_-_56709674 Show fit	44.51	ENST00000551286.1 ENST00000549318.1	CNPY2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit RP11-977G19.10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	canopy FGF signaling regulator 2 Uncharacterized protein
chr17_+_49337881 Show fit	44.23	ENST00000225298.7	UTP18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP18 small subunit (SSU) processome component homolog (yeast)
chr5_+_122110691 Show fit	44.16	ENST00000379516.2 ENST00000505934.1 ENST00000514949.1	SNX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorting nexin 2
chr6_+_30689350 Show fit	44.01	ENST00000330914.3	TUBB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, beta class I
chr1_-_222885770 Show fit	43.44	ENST00000355727.2 ENST00000340020.6	AIDA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	axin interactor, dorsalization associated
chr1_-_51425902 Show fit	43.12	ENST00000396153.2	FAF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fas (TNFRSF6) associated factor 1
chr10_+_70883908 Show fit	42.75	ENST00000263559.6 ENST00000395098.1 ENST00000546041.1 ENST00000541711.1	VPS26A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 26 homolog A (S. pombe)
chr20_+_48552908 Show fit	42.05	ENST00000244061.2	RNF114 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 114
chr18_+_3247413 Show fit	41.54	ENST00000579226.1 ENST00000217652.3	MYL12A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 12A, regulatory, non-sarcomeric
chr1_-_78148324 Show fit	41.26	ENST00000370801.3 ENST00000433749.1	ZZZ3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, ZZ-type containing 3
chr7_+_100464760 Show fit	39.84	ENST00000200457.4	TRIP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 6
chr15_-_72668805 Show fit	39.25	ENST00000268097.5	HEXA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hexosaminidase A (alpha polypeptide)
chr21_-_38445470 Show fit	38.71	ENST00000399098.1	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr11_+_63706444 Show fit	38.66	ENST00000377793.4 ENST00000456907.2 ENST00000539656.1	NAA40 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr6_-_43197189 Show fit	38.59	ENST00000509253.1 ENST00000393987.2 ENST00000230431.6	DNPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chrX_+_100663243 Show fit	38.06	ENST00000316594.5	HNRNPH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_+_36562132 Show fit	37.91	ENST00000373715.6 ENST00000339436.7	SRSF3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 3
chr7_-_99699538 Show fit	37.80	ENST00000343023.6 ENST00000303887.5	MCM7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 7
chr12_-_56710118 Show fit	37.68	ENST00000273308.4	CNPY2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	canopy FGF signaling regulator 2
chr18_+_3247779 Show fit	37.57	ENST00000578611.1 ENST00000583449.1	MYL12A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 12A, regulatory, non-sarcomeric
chr6_+_30689401 Show fit	37.55	ENST00000396389.1 ENST00000396384.1	TUBB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, beta class I
chr5_+_133707252 Show fit	37.48	ENST00000506787.1 ENST00000507277.1	UBE2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2B
chr3_-_113465065 Show fit	37.35	ENST00000497255.1 ENST00000478020.1 ENST00000240922.3 ENST00000493900.1	NAA50 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_-_44223138 Show fit	36.96	ENST00000260665.7	LRPPRC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine-rich pentatricopeptide repeat containing
chr17_+_49230897 Show fit	36.84	ENST00000393196.3 ENST00000336097.3 ENST00000480143.1 ENST00000511355.1 ENST00000013034.3 ENST00000393198.3 ENST00000608447.1 ENST00000393193.2 ENST00000376392.6 ENST00000555572.1	NME1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit NME1-NME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit NME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NME/NM23 nucleoside diphosphate kinase 1 NME1-NME2 readthrough NME/NM23 nucleoside diphosphate kinase 2
chrX_+_23685563 Show fit	36.49	ENST00000379341.4	PRDX4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxiredoxin 4
chr1_-_51425772 Show fit	36.27	ENST00000371778.4	FAF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fas (TNFRSF6) associated factor 1
chr19_+_12848299 Show fit	35.99	ENST00000357332.3	ASNA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr1_-_155232221 Show fit	35.83	ENST00000355379.3	SCAMP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	secretory carrier membrane protein 3
chr20_+_31407692 Show fit	35.75	ENST00000375571.5	MAPRE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule-associated protein, RP/EB family, member 1
chr1_+_32479430 Show fit	35.62	ENST00000327300.7 ENST00000492989.1	KHDRBS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KH domain containing, RNA binding, signal transduction associated 1
chr8_+_98788003 Show fit	35.44	ENST00000521545.2	LAPTM4B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysosomal protein transmembrane 4 beta
chr2_-_10588630 Show fit	35.34	ENST00000234111.4	ODC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ornithine decarboxylase 1
chr17_-_47492164 Show fit	35.27	ENST00000512041.2 ENST00000446735.1 ENST00000504124.1	PHB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prohibitin
chr1_-_3816779 Show fit	35.15	ENST00000361605.3	C1orf174 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 174
chr8_+_55047763 Show fit	35.14	ENST00000260102.4 ENST00000519831.1	MRPL15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L15
chr14_+_35591928 Show fit	35.06	ENST00000605870.1 ENST00000557404.3	KIAA0391 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0391
chr7_+_150759634 Show fit	34.72	ENST00000392826.2 ENST00000461735.1	SLC4A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 4 (anion exchanger), member 2
chr12_+_72148614 Show fit	34.65	ENST00000261263.3	RAB21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB21, member RAS oncogene family
chr21_-_38445011 Show fit	34.36	ENST00000464265.1 ENST00000399102.1	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr6_-_33385902 Show fit	34.34	ENST00000374500.5	CUTA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr1_-_154600421 Show fit	34.24	ENST00000368471.3 ENST00000292205.5	ADAR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenosine deaminase, RNA-specific
chr5_+_172410757 Show fit	34.15	ENST00000519374.1 ENST00000519911.1 ENST00000265093.4 ENST00000517669.1	ATP6V0E1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr1_-_28559502 Show fit	34.10	ENST00000263697.4	DNAJC8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily C, member 8
chr11_+_114310102 Show fit	33.73	ENST00000265881.5	REXO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA exonuclease 2
chrX_+_48432892 Show fit	33.66	ENST00000376759.3 ENST00000430348.2	RBM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif (RNP1, RRM) protein 3
chr2_-_26101374 Show fit	33.65	ENST00000435504.4	ASXL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	additional sex combs like 2 (Drosophila)
chrX_+_48433326 Show fit	33.34	ENST00000376755.1	RBM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif (RNP1, RRM) protein 3
chr1_+_42921761 Show fit	32.93	ENST00000372562.1	PPCS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphopantothenoylcysteine synthetase
chr17_-_7218403 Show fit	32.76	ENST00000570780.1	GPS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein pathway suppressor 2
chr17_+_7476136 Show fit	32.70	ENST00000582169.1 ENST00000578754.1 ENST00000578495.1 ENST00000293831.8 ENST00000380512.5 ENST00000585024.1 ENST00000583802.1 ENST00000577269.1 ENST00000584784.1 ENST00000582746.1	EIF4A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 4A1
chr19_+_50180317 Show fit	32.65	ENST00000534465.1	PRMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein arginine methyltransferase 1
chr11_+_65770227 Show fit	32.49	ENST00000527348.1	BANF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	barrier to autointegration factor 1
chr5_+_159848854 Show fit	32.37	ENST00000517480.1 ENST00000520452.1 ENST00000393964.1	PTTG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pituitary tumor-transforming 1
chr16_+_88923494 Show fit	32.29	ENST00000567895.1 ENST00000301021.3 ENST00000565504.1 ENST00000567312.1 ENST00000568583.1 ENST00000561840.1	TRAPPC2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	trafficking protein particle complex 2-like
chr15_-_65281775 Show fit	31.91	ENST00000433215.2 ENST00000558415.1 ENST00000557795.1	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr12_-_65153175 Show fit	31.72	ENST00000543646.1 ENST00000542058.1 ENST00000258145.3	GNS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosamine (N-acetyl)-6-sulfatase
chr15_+_45315302 Show fit	31.67	ENST00000267814.9	SORD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorbitol dehydrogenase
chr12_+_57624085 Show fit	31.48	ENST00000553474.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_155232047 Show fit	31.24	ENST00000302631.3	SCAMP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	secretory carrier membrane protein 3
chr3_-_195163803 Show fit	31.19	ENST00000326793.6	ACAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr12_+_56109926 Show fit	31.13	ENST00000547076.1	BLOC1S1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	biogenesis of lysosomal organelles complex-1, subunit 1
chr3_+_140660743 Show fit	31.12	ENST00000453248.2	SLC25A36 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr2_+_113403434 Show fit	31.12	ENST00000272542.3	SLC20A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 20 (phosphate transporter), member 1
chrX_+_41192595 Show fit	31.04	ENST00000399959.2	DDX3X Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr22_-_39096661 Show fit	30.61	ENST00000216039.5	JOSD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Josephin domain containing 1
chr1_-_110950564 Show fit	30.45	ENST00000256644.4	LAMTOR5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr19_+_41768401 Show fit	30.24	ENST00000352456.3 ENST00000595018.1 ENST00000597725.1	HNRNPUL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein U-like 1
chr10_+_112327425 Show fit	30.00	ENST00000361804.4	SMC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 3
chrX_-_100872911 Show fit	29.71	ENST00000361910.4 ENST00000539247.1 ENST00000538627.1	ARMCX6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	armadillo repeat containing, X-linked 6
chr1_+_43148625 Show fit	29.60	ENST00000436427.1	YBX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Y box binding protein 1
chr21_-_38445443 Show fit	29.51	ENST00000360525.4	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr17_-_7137857 Show fit	29.21	ENST00000005340.5	DVL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dishevelled segment polarity protein 2
chr14_-_35591433 Show fit	28.91	ENST00000261475.5 ENST00000555644.1	PPP2R3C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B'', gamma
chr21_-_38445297 Show fit	28.87	ENST00000430792.1 ENST00000399103.1	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr22_+_20105259 Show fit	28.78	ENST00000416427.1 ENST00000421656.1 ENST00000423859.1 ENST00000418705.2	RANBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAN binding protein 1
chr12_-_76953573 Show fit	28.71	ENST00000549646.1 ENST00000550628.1 ENST00000553139.1 ENST00000261183.3 ENST00000393250.4	OSBPL8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	oxysterol binding protein-like 8
chr1_-_8939265 Show fit	28.51	ENST00000489867.1	ENO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 1, (alpha)
chr1_-_68962805 Show fit	28.40	ENST00000370966.5	DEPDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEP domain containing 1
chr7_+_73868220 Show fit	28.14	ENST00000455841.2	GTF2IRD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GTF2I repeat domain containing 1
chr6_-_7313381 Show fit	28.04	ENST00000489567.1 ENST00000479365.1 ENST00000462112.1 ENST00000397511.2 ENST00000534851.1 ENST00000474597.1 ENST00000244763.4	SSR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal sequence receptor, alpha
chr21_-_46238034 Show fit	27.92	ENST00000332859.6	SUMO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 3
chr11_+_114310164 Show fit	27.85	ENST00000544196.1 ENST00000539754.1 ENST00000539275.1	REXO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA exonuclease 2
chr11_-_61560254 Show fit	27.71	ENST00000543510.1	TMEM258 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 258
chr3_+_33840050 Show fit	27.65	ENST00000457054.2 ENST00000413073.1	PDCD6IP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	programmed cell death 6 interacting protein
chr5_+_34656569 Show fit	27.64	ENST00000428746.2	RAI14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoic acid induced 14
chr11_+_114310237 Show fit	27.62	ENST00000539119.1	REXO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA exonuclease 2
chr2_-_26101314 Show fit	27.59	ENST00000336112.4 ENST00000272341.4	ASXL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	additional sex combs like 2 (Drosophila)
chr2_-_198299726 Show fit	27.58	ENST00000409915.4 ENST00000487698.1 ENST00000414963.2 ENST00000335508.6	SF3B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	splicing factor 3b, subunit 1, 155kDa
chr1_-_39325431 Show fit	27.57	ENST00000373001.3	RRAGC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras-related GTP binding C
chr12_-_76477707 Show fit	27.54	ENST00000551992.1	NAP1L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleosome assembly protein 1-like 1
chr13_+_113951607 Show fit	27.52	ENST00000397181.3	LAMP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysosomal-associated membrane protein 1
chr10_-_43903217 Show fit	27.51	ENST00000357065.4	HNRNPF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr11_-_122931881 Show fit	27.43	ENST00000526110.1 ENST00000227378.3	HSPA8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 70kDa protein 8
chr12_+_57624119 Show fit	27.37	ENST00000555773.1 ENST00000554975.1 ENST00000449049.3 ENST00000393827.4	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_13049413 Show fit	27.11	ENST00000316448.5 ENST00000588454.1	CALR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calreticulin
chr4_-_2935674 Show fit	27.11	ENST00000514800.1	MFSD10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major facilitator superfamily domain containing 10
chr19_-_4670345 Show fit	26.96	ENST00000599630.1 ENST00000262947.3	C19orf10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 19 open reading frame 10
chr15_-_65282232 Show fit	26.47	ENST00000416889.2	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr5_+_126112794 Show fit	26.33	ENST00000261366.5 ENST00000395354.1	LMNB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lamin B1
chr6_+_158589374 Show fit	26.32	ENST00000607778.1	GTF2H5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIH, polypeptide 5
chr4_+_57302297 Show fit	26.30	ENST00000399688.3 ENST00000512576.1	PAICS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr7_+_100271355 Show fit	26.26	ENST00000436220.1 ENST00000424361.1	GNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr21_-_40720974 Show fit	26.07	ENST00000380748.1	HMGN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group nucleosome binding domain 1
chr2_+_131100423 Show fit	25.99	ENST00000409935.1 ENST00000409649.1 ENST00000428740.1	IMP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr11_-_61560053 Show fit	25.90	ENST00000537328.1	TMEM258 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 258
chr19_+_1275917 Show fit	25.90	ENST00000469144.1	C19orf24 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 19 open reading frame 24
chr19_-_8386238 Show fit	25.81	ENST00000301457.2	NDUFA7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr3_+_133292851 Show fit	25.70	ENST00000503932.1	CDV3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CDV3 homolog (mouse)
chr8_+_22224760 Show fit	25.39	ENST00000359741.5 ENST00000520644.1 ENST00000240095.6	SLC39A14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 39 (zinc transporter), member 14
chrX_+_131157322 Show fit	25.32	ENST00000481105.1 ENST00000354719.6 ENST00000394335.2	MST4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Serine/threonine-protein kinase MST4
chr20_+_35202909 Show fit	25.26	ENST00000558530.1 ENST00000558028.1 ENST00000560025.1	TGIF2-C20orf24 Links Ensembl NCBI GeneCards UniProt NextProt Show fit TGIF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TGIF2-C20orf24 readthrough TGFB-induced factor homeobox 2
chr12_+_53645870 Show fit	25.17	ENST00000329548.4	MFSD5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major facilitator superfamily domain containing 5
chr7_+_100271446 Show fit	25.08	ENST00000419828.1 ENST00000427895.1	GNB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_-_43638168 Show fit	25.01	ENST00000431635.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EBNA1 binding protein 2
chr2_+_198365095 Show fit	24.95	ENST00000409468.1	HSPE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 10kDa protein 1
chr17_+_49243639 Show fit	24.93	ENST00000512737.1 ENST00000503064.1	NME1-NME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NME1-NME2 readthrough
chr13_+_27998681 Show fit	24.72	ENST00000381140.4	GTF3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIIA
chr1_+_26798955 Show fit	24.68	ENST00000361427.5	HMGN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group nucleosomal binding domain 2
chr5_+_34656331 Show fit	24.68	ENST00000265109.3	RAI14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoic acid induced 14
chr9_-_19127474 Show fit	24.67	ENST00000380465.3 ENST00000380464.3 ENST00000411567.1 ENST00000276914.2	PLIN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	perilipin 2
chr15_-_65282274 Show fit	24.37	ENST00000204566.2	SPG21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr9_+_117350009 Show fit	24.30	ENST00000374050.3	ATP6V1G1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr12_+_104359576 Show fit	24.23	ENST00000392872.3 ENST00000436021.2	TDG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymine-DNA glycosylase
chr14_-_54955721 Show fit	24.20	ENST00000554908.1	GMFB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glia maturation factor, beta
chr19_+_50180507 Show fit	24.10	ENST00000454376.2 ENST00000524771.1	PRMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein arginine methyltransferase 1
chr3_+_127323739 Show fit	24.04	ENST00000491422.1	MCM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	minichromosome maintenance complex component 2
chr8_-_144679296 Show fit	24.04	ENST00000317198.6	EEF1D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr18_+_12947981 Show fit	23.59	ENST00000262124.11	SEH1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEH1-like (S. cerevisiae)
chr2_-_98612350 Show fit	23.57	ENST00000186436.5	TMEM131 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 131
chr7_+_150065879 Show fit	23.57	ENST00000397281.2 ENST00000444957.1 ENST00000466559.1 ENST00000489432.2 ENST00000475514.1 ENST00000482680.1 ENST00000488943.1 ENST00000518514.1 ENST00000478789.1	REPIN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit ZNF775 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	replication initiator 1 zinc finger protein 775
chr19_+_1067271 Show fit	23.50	ENST00000536472.1 ENST00000590214.1	HMHA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histocompatibility (minor) HA-1
chr3_+_52719936 Show fit	23.45	ENST00000418458.1 ENST00000394799.2	GNL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein-like 3 (nucleolar)
chr21_-_46237959 Show fit	23.23	ENST00000397898.3 ENST00000411651.2	SUMO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small ubiquitin-like modifier 3
chr8_+_22224811 Show fit	23.16	ENST00000381237.1	SLC39A14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 39 (zinc transporter), member 14
chr12_+_57623869 Show fit	22.83	ENST00000414700.3 ENST00000557703.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr20_-_61847586 Show fit	22.83	ENST00000370339.3	YTHDF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	YTH domain family, member 1
chr4_-_83295103 Show fit	22.79	ENST00000313899.7 ENST00000352301.4 ENST00000509107.1 ENST00000353341.4 ENST00000541060.1	HNRNPD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr7_+_12726474 Show fit	22.73	ENST00000396662.1 ENST00000356797.3 ENST00000396664.2	ARL4A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 4A
chr15_+_75628394 Show fit	22.65	ENST00000564815.1 ENST00000338995.6	COMMD4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 4
chr5_+_133706865 Show fit	22.63	ENST00000265339.2	UBE2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2B
chr4_-_54930790 Show fit	22.57	ENST00000263921.3	CHIC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cysteine-rich hydrophobic domain 2
chr11_-_85779971 Show fit	22.47	ENST00000393346.3	PICALM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol binding clathrin assembly protein
chr19_+_10765003 Show fit	22.42	ENST00000407004.3 ENST00000589998.1 ENST00000589600.1	ILF3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin enhancer binding factor 3, 90kDa
chr11_-_64013663 Show fit	22.34	ENST00000392210.2	PPP1R14B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_+_131157290 Show fit	22.33	ENST00000394334.2	MST4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Serine/threonine-protein kinase MST4
chr15_+_75628232 Show fit	22.32	ENST00000267935.8 ENST00000567195.1	COMMD4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COMM domain containing 4
chr15_+_44084503 Show fit	22.25	ENST00000409960.2 ENST00000409646.1 ENST00000594896.1 ENST00000339624.5 ENST00000409291.1 ENST00000402131.1 ENST00000403425.1 ENST00000430901.1	SERF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small EDRK-rich factor 2
chr10_-_99258135 Show fit	22.19	ENST00000327238.10 ENST00000327277.7 ENST00000355839.6 ENST00000437002.1 ENST00000422685.1	MMS19 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr10_+_75910960 Show fit	22.18	ENST00000539909.1 ENST00000286621.2	ADK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenosine kinase
chr10_+_81107271 Show fit	22.15	ENST00000448165.1	PPIF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peptidylprolyl isomerase F
chr17_+_30677136 Show fit	21.99	ENST00000394670.4 ENST00000321233.6 ENST00000394673.2 ENST00000341711.6 ENST00000579634.1 ENST00000580759.1 ENST00000342555.6 ENST00000577908.1 ENST00000394679.5 ENST00000582165.1	ZNF207 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 207
chr19_-_10530784 Show fit	21.99	ENST00000593124.1	CDC37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 37
chr10_+_124913930 Show fit	21.95	ENST00000368858.5	BUB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BUB3 mitotic checkpoint protein
chr21_-_40720995 Show fit	21.95	ENST00000380749.5	HMGN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group nucleosome binding domain 1
chr19_+_797443 Show fit	21.88	ENST00000394601.4 ENST00000589575.1	PTBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polypyrimidine tract binding protein 1

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
119.6	598.1	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
42.5	169.9	GO:0046452	dihydrofolate metabolic process(GO:0046452)
27.9	111.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
22.0	66.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
20.0	60.1	GO:0010845	positive regulation of reciprocal meiotic recombination(GO:0010845)
19.8	178.0	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
17.5	122.2	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
17.1	85.3	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
16.8	50.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
15.2	45.7	GO:0090149	mitochondrial membrane fission(GO:0090149)
14.9	44.7	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
14.7	132.2	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
14.6	43.8	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
14.4	57.6	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
13.8	27.6	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
13.7	41.0	GO:0044209	AMP salvage(GO:0044209)
13.6	54.3	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
12.9	51.7	GO:0070495	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
12.8	38.3	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
12.4	61.9	GO:0014886	transition between slow and fast fiber(GO:0014886)
12.4	74.3	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
11.9	35.8	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
11.9	35.7	GO:0043490	malate-aspartate shuttle(GO:0043490)
11.4	34.2	GO:1900368	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
10.6	31.7	GO:0006059	hexitol metabolic process(GO:0006059)
10.5	63.2	GO:0090646	mitochondrial tRNA processing(GO:0090646)
10.5	104.8	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
10.5	83.8	GO:0016139	glycoside catabolic process(GO:0016139)
10.4	10.4	GO:2000157	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
10.3	31.0	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
10.0	10.0	GO:0090291	negative regulation of osteoclast proliferation(GO:0090291)
9.9	79.2	GO:0060155	platelet dense granule organization(GO:0060155)
9.8	98.3	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
9.8	39.1	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
9.8	48.8	GO:0042256	mature ribosome assembly(GO:0042256)
9.7	48.5	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
9.6	28.7	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
9.3	27.9	GO:0061470	T follicular helper cell differentiation(GO:0061470)
9.2	36.6	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
9.1	54.7	GO:2000323	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
8.9	35.6	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
8.1	24.2	GO:0006864	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
8.0	39.8	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
7.9	15.9	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
7.6	22.8	GO:1901355	response to rapamycin(GO:1901355)
7.3	66.0	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
7.3	51.3	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
7.2	7.2	GO:0016071	mRNA metabolic process(GO:0016071)
7.1	49.5	GO:0090204	protein localization to nuclear pore(GO:0090204)
7.0	34.8	GO:0006344	maintenance of chromatin silencing(GO:0006344)
6.9	61.8	GO:1902903	regulation of fibril organization(GO:1902903)
6.8	47.9	GO:1902570	protein localization to nucleolus(GO:1902570)
6.8	20.4	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
6.6	79.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
6.6	131.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
6.3	50.4	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
6.2	24.6	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
6.0	23.9	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
6.0	185.6	GO:0090383	phagosome acidification(GO:0090383)
5.9	29.5	GO:0016321	female meiosis chromosome segregation(GO:0016321)
5.8	58.5	GO:0021769	orbitofrontal cortex development(GO:0021769)
5.8	57.7	GO:0071578	zinc II ion transmembrane import(GO:0071578)
5.6	16.7	GO:0006166	purine ribonucleoside salvage(GO:0006166)
5.6	61.2	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
5.3	21.2	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
5.1	51.0	GO:0015074	DNA integration(GO:0015074)
5.1	35.5	GO:2001171	positive regulation of ATP biosynthetic process(GO:2001171)
5.0	15.1	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
5.0	15.0	GO:0031938	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
4.9	9.8	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
4.8	19.3	GO:0046035	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
4.8	19.3	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
4.7	37.3	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
4.6	13.8	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
4.5	27.1	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
4.4	17.8	GO:0048254	snoRNA localization(GO:0048254)
4.4	13.3	GO:0072711	cellular response to hydroxyurea(GO:0072711)
4.4	48.8	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
4.4	44.2	GO:0018202	peptidyl-histidine modification(GO:0018202)
4.2	29.6	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
4.2	21.1	GO:0006740	NADPH regeneration(GO:0006740)
4.2	50.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
4.1	20.7	GO:0009213	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
4.0	15.8	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
3.9	39.4	GO:0045008	depyrimidination(GO:0045008)
3.9	11.7	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
3.8	42.3	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
3.8	11.5	GO:1903674	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
3.8	188.9	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
3.8	15.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
3.7	11.2	GO:0005997	xylulose metabolic process(GO:0005997)
3.6	28.9	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
3.5	10.5	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
3.5	21.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
3.5	31.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
3.5	24.2	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
3.4	10.3	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
3.4	20.7	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
3.4	44.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
3.3	19.9	GO:0015866	adenine transport(GO:0015853) ADP transport(GO:0015866) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
3.3	33.1	GO:0006294	nucleotide-excision repair, preincision complex assembly(GO:0006294)
3.3	36.1	GO:0030043	actin filament fragmentation(GO:0030043)
3.3	9.8	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
3.3	13.1	GO:0002572	pro-T cell differentiation(GO:0002572)
3.2	189.2	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
3.2	9.5	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
3.2	9.5	GO:0010587	miRNA catabolic process(GO:0010587)
3.1	9.4	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
3.1	12.5	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
3.1	9.4	GO:0006014	D-ribose metabolic process(GO:0006014)
3.1	15.6	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
3.1	9.2	GO:0022604	regulation of cell morphogenesis(GO:0022604)
3.0	18.3	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
3.0	9.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
3.0	30.3	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
3.0	15.1	GO:0019348	dolichol metabolic process(GO:0019348)
3.0	9.0	GO:0072719	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) cellular response to cisplatin(GO:0072719)
3.0	30.0	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
2.9	14.7	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
2.9	14.7	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.9	8.6	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
2.8	8.5	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
2.8	19.7	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.8	16.7	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
2.8	11.0	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
2.7	59.6	GO:0030488	tRNA methylation(GO:0030488)
2.7	10.6	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
2.7	18.6	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
2.6	34.1	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.6	101.8	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
2.6	38.6	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
2.6	23.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
2.6	5.1	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
2.5	89.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
2.5	5.1	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
2.5	12.6	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
2.5	12.6	GO:0006041	glucosamine metabolic process(GO:0006041)
2.5	47.5	GO:0042340	keratan sulfate catabolic process(GO:0042340)
2.5	7.4	GO:0051684	maintenance of Golgi location(GO:0051684)
2.4	7.3	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
2.4	7.2	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
2.4	14.4	GO:0050685	positive regulation of mRNA processing(GO:0050685)
2.4	7.1	GO:0032661	regulation of interleukin-18 production(GO:0032661)
2.4	11.8	GO:0016240	autophagosome docking(GO:0016240)
2.4	4.7	GO:0019087	transformation of host cell by virus(GO:0019087)
2.4	49.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
2.3	15.8	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
2.3	72.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.2	6.7	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.2	8.9	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
2.2	15.5	GO:0008295	spermidine biosynthetic process(GO:0008295)
2.1	15.0	GO:0090160	Golgi to lysosome transport(GO:0090160)
2.1	66.3	GO:0032008	positive regulation of TOR signaling(GO:0032008)
2.1	10.6	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.1	12.6	GO:0018206	peptidyl-methionine modification(GO:0018206)
2.1	6.3	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
2.1	10.4	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
2.1	27.0	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
2.1	10.3	GO:2000253	positive regulation of feeding behavior(GO:2000253)
2.1	8.2	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
2.0	6.0	GO:1904245	regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
2.0	139.2	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
2.0	43.0	GO:0006337	nucleosome disassembly(GO:0006337)
1.9	5.8	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.9	15.3	GO:0044351	macropinocytosis(GO:0044351)
1.9	17.1	GO:0002183	cytoplasmic translational initiation(GO:0002183)
1.9	49.3	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.9	17.1	GO:0051451	myoblast migration(GO:0051451)
1.9	5.7	GO:1902498	regulation of protein autoubiquitination(GO:1902498) positive regulation of protein autoubiquitination(GO:1902499)
1.9	39.4	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.9	31.9	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
1.9	16.9	GO:0072257	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.9	29.8	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
1.9	33.5	GO:0097502	mannosylation(GO:0097502)
1.9	7.4	GO:0072553	terminal button organization(GO:0072553)
1.8	74.0	GO:0097421	liver regeneration(GO:0097421)
1.8	31.2	GO:0036010	protein localization to endosome(GO:0036010)
1.8	7.3	GO:0043335	protein unfolding(GO:0043335)
1.8	12.7	GO:0015936	coenzyme A metabolic process(GO:0015936)
1.8	7.2	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
1.8	10.6	GO:0006689	ganglioside catabolic process(GO:0006689)
1.8	21.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
1.7	10.2	GO:0032328	alanine transport(GO:0032328)
1.7	30.6	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
1.7	18.5	GO:0033572	transferrin transport(GO:0033572)
1.7	5.0	GO:0006258	UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
1.6	9.8	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.6	16.1	GO:0006983	ER overload response(GO:0006983)
1.6	62.7	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
1.6	8.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.6	9.5	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
1.6	53.3	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.5	4.6	GO:0051661	maintenance of centrosome location(GO:0051661)
1.5	18.4	GO:0007379	segment specification(GO:0007379)
1.5	18.4	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
1.5	42.9	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
1.5	22.6	GO:0038092	nodal signaling pathway(GO:0038092)
1.5	16.3	GO:0090161	Golgi ribbon formation(GO:0090161)
1.5	4.4	GO:0032986	protein-DNA complex disassembly(GO:0032986)
1.5	4.4	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
1.4	10.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
1.4	20.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
1.4	12.9	GO:0051382	kinetochore assembly(GO:0051382)
1.4	22.9	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
1.4	7.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
1.4	102.4	GO:0006342	chromatin silencing(GO:0006342)
1.4	303.7	GO:0006364	rRNA processing(GO:0006364)
1.4	20.5	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
1.4	13.6	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
1.4	9.5	GO:0015755	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.3	8.1	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
1.3	9.4	GO:0042276	error-prone translesion synthesis(GO:0042276)
1.3	14.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
1.3	9.0	GO:0033484	nitric oxide homeostasis(GO:0033484)
1.3	81.6	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
1.3	12.5	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.2	6.1	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
1.2	22.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.2	22.0	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
1.2	7.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
1.2	22.7	GO:0031639	plasminogen activation(GO:0031639)
1.2	45.8	GO:0046329	negative regulation of JNK cascade(GO:0046329)
1.2	9.4	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
1.1	10.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
1.1	22.8	GO:0045948	positive regulation of translational initiation(GO:0045948)
1.1	1.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.1	76.2	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
1.1	8.9	GO:0048752	semicircular canal morphogenesis(GO:0048752)
1.1	4.4	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
1.1	24.0	GO:0009303	rRNA transcription(GO:0009303)
1.1	3.2	GO:0015680	intracellular copper ion transport(GO:0015680)
1.1	1.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
1.1	3.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.0	15.5	GO:0030050	vesicle transport along actin filament(GO:0030050)
1.0	9.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
1.0	30.7	GO:0006378	mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
1.0	2.0	GO:0032639	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.0	12.1	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
1.0	85.7	GO:0070527	platelet aggregation(GO:0070527)
1.0	5.7	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.9	19.8	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.9	24.1	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.9	6.3	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.9	35.3	GO:1901998	toxin transport(GO:1901998)
0.9	81.8	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.9	14.3	GO:0032836	glomerular basement membrane development(GO:0032836)
0.9	4.4	GO:0007498	mesoderm development(GO:0007498)
0.9	8.5	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.8	20.3	GO:0031055	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.8	38.4	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.8	47.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.8	87.1	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.8	23.5	GO:0060260	regulation of transcription initiation from RNA polymerase II promoter(GO:0060260)
0.8	47.4	GO:0031100	organ regeneration(GO:0031100)
0.8	25.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.8	5.3	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.7	11.2	GO:0000338	protein deneddylation(GO:0000338)
0.7	5.9	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.7	2.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.7	8.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.7	8.0	GO:0051601	exocyst localization(GO:0051601)
0.7	10.7	GO:0006265	DNA topological change(GO:0006265)
0.7	3.4	GO:0050957	equilibrioception(GO:0050957)
0.7	7.4	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.7	30.5	GO:0006446	regulation of translational initiation(GO:0006446)
0.7	67.5	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.7	15.2	GO:0015804	neutral amino acid transport(GO:0015804)
0.7	14.5	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.7	4.6	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.6	3.1	GO:0009650	UV protection(GO:0009650)
0.6	140.7	GO:0000375	RNA splicing, via transesterification reactions(GO:0000375)
0.6	16.2	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.6	4.4	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.6	1.8	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.6	3.0	GO:0006824	cobalt ion transport(GO:0006824)
0.6	41.9	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.6	183.7	GO:0010038	response to metal ion(GO:0010038)
0.5	41.9	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.5	2.7	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.5	5.8	GO:0048251	elastic fiber assembly(GO:0048251)
0.5	9.5	GO:0002021	response to dietary excess(GO:0002021)
0.5	33.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.5	7.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.5	2.5	GO:1901490	positive regulation of mast cell chemotaxis(GO:0060754) regulation of lymphangiogenesis(GO:1901490)
0.5	3.4	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.5	1.4	GO:0000255	allantoin metabolic process(GO:0000255)
0.5	6.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.5	10.3	GO:0051904	melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.5	23.3	GO:0015701	bicarbonate transport(GO:0015701)
0.5	24.7	GO:0019915	lipid storage(GO:0019915)
0.5	2.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.4	1.3	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4	5.4	GO:0043457	regulation of cellular respiration(GO:0043457)
0.4	67.6	GO:0070585	protein localization to mitochondrion(GO:0070585)
0.4	3.9	GO:1904350	regulation of protein catabolic process in the vacuole(GO:1904350)
0.4	48.2	GO:0006414	translational elongation(GO:0006414)
0.4	35.5	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.4	26.5	GO:0043488	regulation of mRNA stability(GO:0043488)
0.4	8.8	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.4	4.6	GO:0050872	white fat cell differentiation(GO:0050872)
0.4	18.4	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.4	3.5	GO:0007010	cytoskeleton organization(GO:0007010)
0.4	11.7	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.4	1.2	GO:0070459	prolactin secretion(GO:0070459)
0.4	8.4	GO:0051290	protein heterotetramerization(GO:0051290)
0.4	4.6	GO:0001778	plasma membrane repair(GO:0001778)
0.4	9.0	GO:1902583	intracellular transport of virus(GO:0075733) multi-organism intracellular transport(GO:1902583)
0.4	8.4	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.4	1.1	GO:0046203	spermidine catabolic process(GO:0046203)
0.4	1.8	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.4	4.2	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4	1.1	GO:0045605	negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617)
0.3	10.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.3	7.7	GO:0070207	protein homotrimerization(GO:0070207)
0.3	9.5	GO:0048246	macrophage chemotaxis(GO:0048246)
0.3	15.1	GO:0031640	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.3	21.8	GO:0006334	nucleosome assembly(GO:0006334)
0.3	8.3	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.3	4.5	GO:0006020	inositol metabolic process(GO:0006020)
0.3	8.1	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.3	1.8	GO:1904062	regulation of calcium ion transmembrane transport(GO:1903169) regulation of cation transmembrane transport(GO:1904062)
0.3	4.6	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.3	2.0	GO:0002115	store-operated calcium entry(GO:0002115)
0.3	6.6	GO:0006400	tRNA modification(GO:0006400)
0.3	2.3	GO:0010628	positive regulation of gene expression(GO:0010628)
0.2	5.5	GO:0007015	actin filament organization(GO:0007015)
0.2	4.8	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.2	11.2	GO:0045454	cell redox homeostasis(GO:0045454)
0.2	2.2	GO:0007219	Notch signaling pathway(GO:0007219)
0.2	2.6	GO:0007588	excretion(GO:0007588)
0.2	3.5	GO:0003334	keratinocyte development(GO:0003334)
0.2	4.6	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.2	3.3	GO:0034453	microtubule anchoring(GO:0034453)
0.2	2.7	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.2	1.1	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.2	0.6	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2	4.4	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.1	0.7	GO:1903421	regulation of synaptic vesicle recycling(GO:1903421)
0.1	3.8	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.1	2.3	GO:0006308	DNA catabolic process(GO:0006308)
0.1	1.3	GO:0016180	snRNA processing(GO:0016180)
0.1	3.1	GO:0010608	posttranscriptional regulation of gene expression(GO:0010608)
0.1	2.1	GO:0060009	Sertoli cell development(GO:0060009)
0.1	4.7	GO:0006270	DNA replication initiation(GO:0006270)
0.1	1.9	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.1	6.7	GO:0006401	RNA catabolic process(GO:0006401)
0.1	2.0	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.1	3.1	GO:0061045	negative regulation of wound healing(GO:0061045)
0.1	1.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	12.4	GO:0031424	keratinization(GO:0031424)
0.1	3.1	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.4	GO:2000117	negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.1	3.0	GO:0055010	ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.1	1.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	5.9	GO:2001234	negative regulation of apoptotic signaling pathway(GO:2001234)
0.1	2.0	GO:0033198	response to ATP(GO:0033198)
0.1	4.6	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	1.9	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1	0.9	GO:0007100	mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.1	4.3	GO:0042246	tissue regeneration(GO:0042246)
0.1	4.2	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.1	0.3	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1	2.5	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	0.6	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	7.5	GO:0060041	retina development in camera-type eye(GO:0060041)
0.1	2.4	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.1	0.5	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	1.9	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.1	1.6	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.5	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0	0.6	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	10.3	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	3.5	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.9	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.0	4.7	GO:0071466	cellular response to xenobiotic stimulus(GO:0071466)
0.0	0.4	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	9.0	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.3	GO:1903364	positive regulation of cellular protein catabolic process(GO:1903364)
0.0	0.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:0043585	nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0	0.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.1	GO:0050821	protein stabilization(GO:0050821)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
99.7	598.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
28.2	197.3	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
24.6	98.3	GO:0033186	CAF-1 complex(GO:0033186)
22.3	156.3	GO:0046581	intercellular canaliculus(GO:0046581)
17.4	104.3	GO:0001740	Barr body(GO:0001740)
13.1	131.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
12.8	51.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
12.6	63.2	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
12.6	100.9	GO:0070552	BRISC complex(GO:0070552)
12.1	36.4	GO:1990298	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
12.0	60.1	GO:0033503	HULC complex(GO:0033503)
11.2	67.4	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
11.0	44.1	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
10.5	83.8	GO:0042382	paraspeckles(GO:0042382)
10.5	94.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
10.2	30.6	GO:0030906	retromer, cargo-selective complex(GO:0030906)
10.0	30.0	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
9.0	45.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
9.0	44.9	GO:0071986	Ragulator complex(GO:0071986)
8.9	80.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
8.4	67.6	GO:0097208	alveolar lamellar body(GO:0097208)
8.4	109.3	GO:0042555	MCM complex(GO:0042555)
8.3	33.1	GO:0070985	TFIIK complex(GO:0070985)
8.3	123.8	GO:0005641	nuclear envelope lumen(GO:0005641)
8.1	48.5	GO:0072589	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
8.0	23.9	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
8.0	39.8	GO:0045323	interleukin-1 receptor complex(GO:0045323)
7.6	38.2	GO:0034457	Mpp10 complex(GO:0034457)
7.4	67.0	GO:0000439	core TFIIH complex(GO:0000439)
7.4	44.2	GO:0030905	retromer, tubulation complex(GO:0030905)
7.3	80.5	GO:0033391	chromatoid body(GO:0033391)
7.1	35.3	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
7.0	42.1	GO:0071817	MMXD complex(GO:0071817)
6.8	34.2	GO:0044530	supraspliceosomal complex(GO:0044530)
6.5	32.6	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
6.4	89.8	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
6.0	35.8	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
5.6	16.7	GO:0097447	dendritic tree(GO:0097447)
5.3	37.3	GO:0031415	NatA complex(GO:0031415)
5.0	15.0	GO:0005656	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
4.6	82.5	GO:0031083	BLOC-1 complex(GO:0031083)
4.5	81.1	GO:0034709	methylosome(GO:0034709)
4.5	53.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
4.4	43.9	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
4.4	21.9	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
4.2	29.6	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
4.1	16.5	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
4.1	73.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
4.0	32.2	GO:1990111	spermatoproteasome complex(GO:1990111)
3.9	19.6	GO:0016589	NURF complex(GO:0016589)
3.9	31.3	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
3.7	147.6	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
3.6	10.7	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
3.5	10.6	GO:0005960	glycine cleavage complex(GO:0005960)
3.5	34.9	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
3.4	20.4	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
3.4	16.9	GO:0071148	TEAD-1-YAP complex(GO:0071148)
3.4	23.6	GO:0061700	GATOR2 complex(GO:0061700)
3.3	13.3	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
3.3	112.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
3.2	12.9	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
3.0	24.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
2.9	55.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
2.9	17.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
2.9	42.9	GO:0090543	Flemming body(GO:0090543)
2.8	34.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
2.7	13.6	GO:0005899	insulin receptor complex(GO:0005899)
2.6	10.5	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
2.6	23.6	GO:0005798	Golgi-associated vesicle(GO:0005798)
2.6	7.7	GO:0005879	axonemal microtubule(GO:0005879)
2.6	40.9	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
2.5	12.7	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
2.4	14.7	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
2.3	9.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
2.3	115.7	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.2	17.8	GO:0070761	pre-snoRNP complex(GO:0070761)
2.2	12.9	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
2.1	44.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
2.1	37.6	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
2.0	16.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
2.0	289.6	GO:0015934	large ribosomal subunit(GO:0015934)
1.9	11.7	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
1.9	5.8	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.9	26.7	GO:0097227	sperm annulus(GO:0097227)
1.9	3.7	GO:0035838	growing cell tip(GO:0035838)
1.8	27.6	GO:0005689	U12-type spliceosomal complex(GO:0005689)
1.8	10.9	GO:0008537	proteasome activator complex(GO:0008537)
1.8	7.2	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
1.8	7.2	GO:0071001	U4/U6 snRNP(GO:0071001)
1.8	12.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
1.8	21.5	GO:0030008	TRAPP complex(GO:0030008)
1.7	20.8	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
1.7	41.9	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
1.7	21.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
1.6	6.3	GO:0032044	DSIF complex(GO:0032044)
1.6	48.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
1.5	12.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.5	7.4	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.5	4.4	GO:1903349	omegasome membrane(GO:1903349)
1.5	33.6	GO:0005685	U1 snRNP(GO:0005685)
1.4	29.7	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.4	16.7	GO:0044615	nuclear pore nuclear basket(GO:0044615)
1.4	15.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
1.4	42.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
1.3	10.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.3	123.0	GO:0017053	transcriptional repressor complex(GO:0017053)
1.2	6.2	GO:0035578	azurophil granule lumen(GO:0035578)
1.2	14.7	GO:0000815	ESCRT III complex(GO:0000815)
1.2	152.5	GO:0000776	kinetochore(GO:0000776)
1.2	9.5	GO:0072546	ER membrane protein complex(GO:0072546)
1.2	161.7	GO:0005840	ribosome(GO:0005840)
1.1	12.5	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
1.1	29.6	GO:0000930	gamma-tubulin complex(GO:0000930)
1.1	3.4	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
1.1	84.8	GO:0005758	mitochondrial intermembrane space(GO:0005758)
1.1	17.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
1.1	21.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
1.0	5.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
1.0	8.8	GO:0097413	Lewy body(GO:0097413)
1.0	62.4	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.9	65.1	GO:0005637	nuclear inner membrane(GO:0005637)
0.9	10.9	GO:0031595	nuclear proteasome complex(GO:0031595)
0.9	5.4	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.9	3.6	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.8	116.4	GO:0043202	lysosomal lumen(GO:0043202)
0.8	8.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.8	4.9	GO:0031082	BLOC complex(GO:0031082)
0.8	40.8	GO:0015030	Cajal body(GO:0015030)
0.8	6.8	GO:0032009	early phagosome(GO:0032009)
0.7	8.1	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.7	11.7	GO:0071141	SMAD protein complex(GO:0071141)
0.7	21.6	GO:0099738	cell cortex region(GO:0099738)
0.7	2.8	GO:0001739	sex chromatin(GO:0001739)
0.7	2.7	GO:0055087	Ski complex(GO:0055087)
0.6	2.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.6	3.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.6	14.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.6	97.5	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.6	7.8	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.5	2.5	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5	38.8	GO:0005643	nuclear pore(GO:0005643)
0.5	23.5	GO:0045171	intercellular bridge(GO:0045171)
0.5	67.5	GO:0005681	spliceosomal complex(GO:0005681)
0.5	38.3	GO:0016459	myosin complex(GO:0016459)
0.5	54.1	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.4	4.7	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.4	34.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.4	11.2	GO:0008180	COP9 signalosome(GO:0008180)
0.4	3.1	GO:0032059	bleb(GO:0032059)
0.4	36.5	GO:0005901	caveola(GO:0005901)
0.4	48.6	GO:0030027	lamellipodium(GO:0030027)
0.4	37.9	GO:0016607	nuclear speck(GO:0016607)
0.4	5.9	GO:0009925	basal plasma membrane(GO:0009925)
0.4	3.2	GO:0030686	90S preribosome(GO:0030686)
0.4	34.5	GO:0070821	tertiary granule membrane(GO:0070821)
0.4	1.8	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.3	38.1	GO:0005903	brush border(GO:0005903)
0.3	2.1	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.3	31.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.3	6.1	GO:0071565	npBAF complex(GO:0071564) nBAF complex(GO:0071565)
0.3	12.2	GO:0045095	keratin filament(GO:0045095)
0.3	5.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.3	5.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.3	3.4	GO:0032420	stereocilium(GO:0032420)
0.3	7.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	22.3	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.2	4.6	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	13.5	GO:0045335	phagocytic vesicle(GO:0045335)
0.2	11.4	GO:0000502	proteasome complex(GO:0000502)
0.2	13.6	GO:0005811	lipid particle(GO:0005811)
0.2	23.9	GO:0016605	PML body(GO:0016605)
0.2	4.6	GO:0031264	death-inducing signaling complex(GO:0031264)
0.2	4.6	GO:0043034	costamere(GO:0043034)
0.2	85.7	GO:0005925	focal adhesion(GO:0005925)
0.2	19.2	GO:0001650	fibrillar center(GO:0001650)
0.2	1.8	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.2	8.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	58.3	GO:0005635	nuclear envelope(GO:0005635)
0.2	2.4	GO:0005771	multivesicular body(GO:0005771)
0.2	1.3	GO:0032039	integrator complex(GO:0032039)
0.2	41.2	GO:0019866	mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.2	3.3	GO:0031519	PcG protein complex(GO:0031519)
0.1	2.0	GO:0030426	growth cone(GO:0030426)
0.1	2.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	310.9	GO:0070062	extracellular exosome(GO:0070062)
0.1	1.3	GO:0032587	ruffle membrane(GO:0032587)
0.1	14.7	GO:0031968	organelle outer membrane(GO:0031968)
0.1	7.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	5.8	GO:0005581	collagen trimer(GO:0005581)
0.1	2.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	5.3	GO:0031225	anchored component of membrane(GO:0031225)
0.1	112.4	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	1.2	GO:0030175	filopodium(GO:0030175)
0.1	0.3	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	1.9	GO:0016235	aggresome(GO:0016235)
0.1	1.5	GO:0001533	cornified envelope(GO:0001533)
0.1	3.7	GO:0031901	early endosome membrane(GO:0031901)
0.1	2.1	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.4	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.4	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.8	GO:0000118	histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
35.4	70.7	GO:0016936	galactoside binding(GO:0016936)
26.8	160.9	GO:0019238	cyclohydrolase activity(GO:0019238)
22.2	177.7	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
22.0	66.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
20.6	82.3	GO:0031871	proteinase activated receptor binding(GO:0031871)
19.2	57.6	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
17.7	53.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
17.5	122.2	GO:0004793	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
16.5	66.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
15.0	613.9	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
14.9	44.7	GO:0004730	pseudouridylate synthase activity(GO:0004730)
13.1	131.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
12.8	38.3	GO:0070364	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
12.2	73.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
10.7	85.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
10.1	80.5	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
9.8	39.1	GO:0004850	uridine phosphorylase activity(GO:0004850)
9.6	28.7	GO:0008859	exoribonuclease II activity(GO:0008859)
9.0	27.0	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
8.8	44.2	GO:1990460	leptin receptor binding(GO:1990460)
8.6	103.5	GO:0031386	protein tag(GO:0031386)
8.6	34.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
8.2	253.6	GO:0051059	NF-kappaB binding(GO:0051059)
8.1	48.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
8.1	24.2	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
7.9	31.7	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
7.8	31.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
7.7	46.4	GO:0044388	ubiquitin activating enzyme activity(GO:0004839) small protein activating enzyme binding(GO:0044388)
7.7	38.7	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
7.6	30.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
7.6	22.7	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
7.5	30.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
7.5	30.0	GO:0036033	mediator complex binding(GO:0036033)
6.9	48.5	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
6.7	40.0	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
6.5	19.6	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
6.5	291.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
6.3	145.6	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
6.2	31.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
5.9	17.8	GO:0030984	kininogen binding(GO:0030984)
5.6	67.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
5.5	32.9	GO:0019776	Atg8 ligase activity(GO:0019776)
5.3	15.9	GO:0033149	FFAT motif binding(GO:0033149)
5.3	15.8	GO:0097322	7SK snRNA binding(GO:0097322)
5.2	57.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
5.2	15.5	GO:0004766	spermidine synthase activity(GO:0004766)
5.2	87.6	GO:0003688	DNA replication origin binding(GO:0003688)
5.1	15.3	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
5.0	15.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
5.0	19.9	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
4.9	19.7	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
4.9	63.8	GO:0043024	ribosomal small subunit binding(GO:0043024)
4.9	14.7	GO:0035500	MH2 domain binding(GO:0035500)
4.8	38.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
4.7	75.7	GO:0004526	ribonuclease P activity(GO:0004526)
4.6	13.8	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
4.3	60.7	GO:1990825	sequence-specific mRNA binding(GO:1990825)
4.3	43.0	GO:1990446	U1 snRNP binding(GO:1990446)
4.2	29.5	GO:0032552	deoxyribonucleotide binding(GO:0032552)
4.1	81.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
4.0	51.7	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
4.0	305.6	GO:0005507	copper ion binding(GO:0005507)
4.0	87.1	GO:0016881	acid-amino acid ligase activity(GO:0016881)
4.0	15.8	GO:0048256	flap endonuclease activity(GO:0048256)
3.8	30.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
3.8	41.7	GO:0008097	5S rRNA binding(GO:0008097)
3.8	82.7	GO:0042609	CD4 receptor binding(GO:0042609)
3.8	26.3	GO:0000182	rDNA binding(GO:0000182)
3.7	18.6	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
3.7	11.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
3.7	33.2	GO:0015288	porin activity(GO:0015288)
3.7	29.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
3.6	7.1	GO:0043398	HLH domain binding(GO:0043398)
3.5	14.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
3.5	10.4	GO:0005047	signal recognition particle binding(GO:0005047)
3.5	10.4	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
3.4	20.7	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
3.4	72.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
3.3	13.0	GO:0004348	glucosylceramidase activity(GO:0004348)
3.2	54.0	GO:0019206	nucleoside kinase activity(GO:0019206)
3.2	44.4	GO:0000339	RNA cap binding(GO:0000339)
3.1	12.5	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
3.1	9.4	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702) oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
3.1	64.8	GO:0032794	GTPase activating protein binding(GO:0032794)
3.0	24.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
3.0	9.0	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
3.0	59.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
2.9	31.9	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
2.9	8.6	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
2.9	17.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
2.7	30.2	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
2.7	91.1	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
2.6	10.6	GO:0004047	aminomethyltransferase activity(GO:0004047)
2.6	28.3	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
2.6	56.5	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
2.5	12.7	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
2.5	9.9	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
2.5	47.0	GO:0005149	interleukin-1 receptor binding(GO:0005149)
2.4	7.2	GO:0004832	valine-tRNA ligase activity(GO:0004832)
2.4	113.2	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
2.3	13.9	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
2.3	11.5	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
2.3	27.1	GO:0019534	toxin transporter activity(GO:0019534)
2.2	44.8	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
2.2	13.0	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
2.2	13.0	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.1	8.4	GO:0032038	myosin II heavy chain binding(GO:0032038)
2.1	29.4	GO:0016018	cyclosporin A binding(GO:0016018)
2.1	14.7	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.1	22.8	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
2.1	10.3	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
2.0	21.6	GO:0051434	BH3 domain binding(GO:0051434)
1.9	9.7	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
1.9	98.8	GO:0016831	carboxy-lyase activity(GO:0016831)
1.9	34.7	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
1.9	11.6	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
1.9	5.8	GO:0070699	type II activin receptor binding(GO:0070699)
1.9	100.6	GO:0003743	translation initiation factor activity(GO:0003743)
1.9	5.6	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
1.8	38.6	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
1.8	18.4	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.8	41.9	GO:0001056	RNA polymerase III activity(GO:0001056)
1.8	7.2	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
1.8	71.4	GO:0048487	beta-tubulin binding(GO:0048487)
1.8	10.7	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
1.8	12.4	GO:0032051	clathrin light chain binding(GO:0032051)
1.8	22.8	GO:0003680	AT DNA binding(GO:0003680)
1.7	42.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
1.7	80.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
1.7	27.7	GO:0017049	GTP-Rho binding(GO:0017049)
1.7	20.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
1.7	15.2	GO:0070883	pre-miRNA binding(GO:0070883)
1.7	31.6	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.6	9.8	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.6	11.2	GO:0001849	complement component C1q binding(GO:0001849)
1.6	14.3	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
1.6	20.4	GO:0035613	RNA stem-loop binding(GO:0035613)
1.6	10.9	GO:0061133	endopeptidase activator activity(GO:0061133)
1.5	6.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
1.5	6.1	GO:0030305	beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
1.5	16.7	GO:0008139	nuclear localization sequence binding(GO:0008139)
1.5	7.5	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.5	40.1	GO:0051010	microtubule plus-end binding(GO:0051010)
1.5	26.3	GO:0043274	phospholipase binding(GO:0043274)
1.5	8.8	GO:0003998	acylphosphatase activity(GO:0003998)
1.4	23.1	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
1.4	8.3	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.4	34.3	GO:0003746	translation elongation factor activity(GO:0003746)
1.4	9.5	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
1.3	25.9	GO:0004697	protein kinase C activity(GO:0004697)
1.2	21.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
1.2	8.7	GO:0000832	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
1.2	41.8	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
1.2	17.8	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
1.2	4.7	GO:0033906	protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
1.2	1.2	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.2	26.8	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
1.2	2.3	GO:0004530	deoxyribonuclease I activity(GO:0004530)
1.2	34.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
1.1	245.3	GO:0003735	structural constituent of ribosome(GO:0003735)
1.1	10.2	GO:0043426	MRF binding(GO:0043426)
1.1	38.5	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
1.1	15.3	GO:0010857	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
1.1	75.5	GO:0019003	GDP binding(GO:0019003)
1.1	31.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
1.0	27.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.0	10.9	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.9	81.4	GO:0032947	protein complex scaffold(GO:0032947)
0.9	13.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.8	9.1	GO:0016413	palmitoyl-CoA hydrolase activity(GO:0016290) O-acetyltransferase activity(GO:0016413)
0.8	5.7	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.8	25.7	GO:0000049	tRNA binding(GO:0000049)
0.8	93.3	GO:0008565	protein transporter activity(GO:0008565)
0.8	7.0	GO:0003993	acid phosphatase activity(GO:0003993)
0.8	6.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.8	4.6	GO:0070513	death domain binding(GO:0070513)
0.7	15.7	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7	8.6	GO:0048156	tau protein binding(GO:0048156)
0.7	13.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7	5.7	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.7	19.6	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.7	4.7	GO:0004046	aminoacylase activity(GO:0004046)
0.7	5.3	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.7	2.0	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.7	4.6	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.6	2.6	GO:0001054	RNA polymerase I activity(GO:0001054)
0.6	17.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.6	10.5	GO:0034185	apolipoprotein binding(GO:0034185)
0.6	15.2	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.6	2.4	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.6	13.5	GO:0070064	proline-rich region binding(GO:0070064)
0.6	5.8	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6	7.2	GO:0008143	poly(A) binding(GO:0008143)
0.5	29.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.5	3.7	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.5	23.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.5	3.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.5	37.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.5	5.5	GO:0097602	cullin family protein binding(GO:0097602)
0.5	15.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.5	13.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.5	15.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.5	32.7	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.5	5.0	GO:0070569	uridylyltransferase activity(GO:0070569)
0.4	13.2	GO:0003727	single-stranded RNA binding(GO:0003727)
0.4	17.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.4	2.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.4	5.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.4	35.8	GO:0001618	virus receptor activity(GO:0001618)
0.4	45.3	GO:0051082	unfolded protein binding(GO:0051082)
0.4	1.1	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.4	1.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.4	2.1	GO:0098821	BMP receptor activity(GO:0098821)
0.3	23.0	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.3	54.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.3	8.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.3	1.6	GO:0000403	Y-form DNA binding(GO:0000403)
0.3	15.0	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.3	15.5	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.3	1.1	GO:0050473	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.3	16.1	GO:0003684	damaged DNA binding(GO:0003684)
0.3	6.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	1.1	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3	8.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3	3.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.3	3.0	GO:0031419	cobalamin binding(GO:0031419)
0.3	41.3	GO:0005178	integrin binding(GO:0005178)
0.3	80.8	GO:0045296	cadherin binding(GO:0045296)
0.3	9.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	0.8	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.2	5.1	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.2	9.5	GO:0008009	chemokine activity(GO:0008009)
0.2	2.0	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2	12.8	GO:0051287	NAD binding(GO:0051287)
0.2	23.2	GO:0047485	protein N-terminus binding(GO:0047485)
0.2	9.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	2.1	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.2	2.0	GO:0048406	nerve growth factor binding(GO:0048406)
0.2	11.9	GO:0008276	protein methyltransferase activity(GO:0008276)
0.2	3.0	GO:0051117	ATPase binding(GO:0051117)
0.2	12.4	GO:0003697	single-stranded DNA binding(GO:0003697)
0.2	1.1	GO:0051425	PTB domain binding(GO:0051425)
0.2	0.7	GO:0031208	POZ domain binding(GO:0031208)
0.2	1.2	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2	1.8	GO:0070566	adenylyltransferase activity(GO:0070566)
0.2	2.0	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	9.7	GO:0051219	phosphoprotein binding(GO:0051219)
0.2	6.2	GO:0030695	GTPase activator activity(GO:0005096) GTPase regulator activity(GO:0030695) nucleoside-triphosphatase regulator activity(GO:0060589)
0.2	162.5	GO:0003723	RNA binding(GO:0003723)
0.1	9.5	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1	0.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	3.6	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	0.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	3.9	GO:0001972	retinoic acid binding(GO:0001972)
0.1	2.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	1.2	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	10.6	GO:0051015	actin filament binding(GO:0051015)
0.1	1.9	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1	4.1	GO:0042826	histone deacetylase binding(GO:0042826)
0.1	2.4	GO:0016504	peptidase activator activity(GO:0016504)
0.1	17.4	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1	3.9	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1	0.6	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.6	GO:0003713	transcription coactivator activity(GO:0003713)
0.1	0.6	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	12.1	GO:0015631	tubulin binding(GO:0015631)
0.1	2.0	GO:0005109	frizzled binding(GO:0005109)
0.1	1.4	GO:0042169	SH2 domain binding(GO:0042169)
0.0	27.8	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	1.8	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	2.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	1.3	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	1.6	GO:0008022	protein C-terminus binding(GO:0008022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
24.6	613.9	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
4.5	13.6	PID S1P S1P2 PATHWAY	S1P2 pathway
3.6	62.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
3.6	500.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
2.4	12.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.3	111.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
2.1	110.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.9	172.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
1.8	103.0	PID ATR PATHWAY	ATR signaling pathway
1.2	131.9	PID CMYB PATHWAY	C-MYB transcription factor network
1.2	87.4	PID ILK PATHWAY	Integrin-linked kinase signaling
1.0	50.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
1.0	62.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
1.0	92.3	PID CDC42 PATHWAY	CDC42 signaling events
1.0	27.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.9	83.1	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.9	21.9	PID IL4 2PATHWAY	IL4-mediated signaling events
0.9	15.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.9	63.8	PID E2F PATHWAY	E2F transcription factor network
0.8	25.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.8	42.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.8	32.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.8	33.1	PID ARF6 PATHWAY	Arf6 signaling events
0.7	25.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.7	14.6	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.7	20.0	PID ATM PATHWAY	ATM pathway
0.6	161.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.6	15.3	PID RHOA PATHWAY	RhoA signaling pathway
0.6	38.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.6	13.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.6	23.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.5	20.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.5	11.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.5	31.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.5	19.5	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.5	9.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	16.9	PID ERBB4 PATHWAY	ErbB4 signaling events
0.4	51.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.4	21.6	PID P73PATHWAY	p73 transcription factor network
0.4	2.5	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.3	4.4	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.3	20.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.3	11.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.3	9.9	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.2	6.1	PID IFNG PATHWAY	IFN-gamma pathway
0.2	2.1	PID BMP PATHWAY	BMP receptor signaling
0.2	19.1	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.2	5.8	PID ALK1 PATHWAY	ALK1 signaling events
0.2	5.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	9.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	5.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	1.7	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	1.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.6	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.6	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.7	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	2.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.0	220.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
9.6	652.0	REACTOME G1 PHASE	Genes involved in G1 Phase
7.8	124.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
7.4	133.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
6.4	185.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
5.7	131.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
5.5	105.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
5.2	47.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
4.9	230.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
4.8	118.9	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
4.1	178.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
4.1	179.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
3.8	34.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
3.7	63.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
3.6	47.1	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
3.6	50.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
3.5	41.9	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
3.1	72.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
2.9	31.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
2.8	59.6	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
2.4	81.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.3	54.1	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
2.2	24.6	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
2.2	51.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
2.1	177.7	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
2.1	104.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
2.0	200.3	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
2.0	320.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
2.0	6.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
1.9	104.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
1.8	27.5	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
1.7	8.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
1.7	163.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
1.7	15.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.5	29.6	REACTOME METABOLISM OF NUCLEOTIDES	Genes involved in Metabolism of nucleotides
1.5	39.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
1.4	28.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
1.4	8.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
1.4	50.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
1.3	21.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
1.3	37.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
1.3	68.9	REACTOME TRANSLATION	Genes involved in Translation
1.2	32.4	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.2	41.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
1.2	32.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.2	19.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
1.1	36.5	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
1.1	32.5	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
1.1	40.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
1.0	8.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
1.0	37.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
1.0	19.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
1.0	35.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.9	37.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.9	78.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.9	17.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.9	11.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.9	64.0	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.9	25.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.8	11.7	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.8	6.6	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.8	135.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.7	54.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.7	5.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.7	14.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.7	18.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.7	28.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.6	46.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.6	27.6	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.6	15.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.6	28.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.6	16.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6	9.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.6	26.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.6	29.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.6	10.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.6	32.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.5	92.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.5	5.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.5	9.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.5	5.5	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.5	10.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.4	29.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.4	9.1	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.4	5.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.4	8.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.4	4.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.4	8.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.4	1.9	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.4	10.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	4.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	4.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	8.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3	8.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.3	5.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.3	2.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3	35.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	21.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.3	6.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.3	3.9	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.3	7.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	2.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.2	5.9	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.2	4.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	4.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2	1.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2	1.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	6.7	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	11.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	9.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	1.9	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	2.2	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
0.1	1.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL