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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MAX_TFEB

Z-value: 2.55

Motif logo

Transcription factors associated with MAX_TFEB

Gene Symbol Gene ID Gene Info
ENSG00000125952.14 MYC associated factor X
ENSG00000112561.13 transcription factor EB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFEBhg19_v2_chr6_-_41701581_41701613-0.767.3e-43Click!
MAXhg19_v2_chr14_-_65569186_655692430.385.9e-09Click!

Activity profile of MAX_TFEB motif

Sorted Z-values of MAX_TFEB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58146128 303.08 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr12_-_58146048 295.02 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr4_-_100871506 104.28 ENST00000296417.5
H2A histone family, member Z
chr8_+_98656336 95.75 ENST00000336273.3
metadherin
chr2_+_216176540 89.25 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_-_109703600 88.98 ENST00000512821.1
CD164 molecule, sialomucin
chr20_+_44520009 85.04 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr20_+_44519948 81.98 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr6_-_33385854 81.60 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr2_+_216176761 80.64 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr4_-_99850243 80.55 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr1_+_44440575 80.41 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr4_-_47465666 78.60 ENST00000381571.4
COMM domain containing 8
chr2_-_10587897 76.21 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr19_+_5681153 71.74 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chrX_-_100662881 70.74 ENST00000218516.3
galactosidase, alpha
chr14_+_20923350 66.08 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr3_+_158519654 65.50 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr6_-_33385655 64.53 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr6_-_109703663 61.35 ENST00000368961.5
CD164 molecule, sialomucin
chr8_+_98656693 60.68 ENST00000519934.1
metadherin
chr1_-_183604794 58.47 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
actin related protein 2/3 complex, subunit 5, 16kDa
chr6_+_160390102 57.23 ENST00000356956.1
insulin-like growth factor 2 receptor
chr12_-_2986107 57.17 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr6_-_33385823 56.19 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr1_+_33116765 54.97 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
retinoblastoma binding protein 4
chr17_-_46688334 54.87 ENST00000239165.7
homeobox B7
chr19_+_8509842 54.26 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
heterogeneous nuclear ribonucleoprotein M
chr5_+_65440032 54.22 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr9_-_34048873 51.92 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
ubiquitin associated protein 2
chr11_-_64014379 51.55 ENST00000309318.3
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr10_-_120840309 50.34 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr12_-_56709786 49.98 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
Uncharacterized protein
canopy FGF signaling regulator 2
chrX_+_23685653 48.81 ENST00000379331.3
peroxiredoxin 4
chr6_-_33385870 48.34 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr12_+_56110247 48.13 ENST00000551926.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr21_-_46237883 47.70 ENST00000397893.3
small ubiquitin-like modifier 3
chr3_+_127317066 47.48 ENST00000265056.7
minichromosome maintenance complex component 2
chr1_+_33116743 46.47 ENST00000414241.3
ENST00000373493.5
retinoblastoma binding protein 4
chr19_+_47634039 46.44 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr10_+_51827648 46.44 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
family with sequence similarity 21, member A
chr5_+_110074685 45.72 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr6_-_109703634 45.48 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164 molecule, sialomucin
chr11_-_47664072 45.11 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
mitochondrial carrier 2
chr12_-_56709674 44.51 ENST00000551286.1
ENST00000549318.1
canopy FGF signaling regulator 2
Uncharacterized protein
chr17_+_49337881 44.23 ENST00000225298.7
UTP18 small subunit (SSU) processome component homolog (yeast)
chr5_+_122110691 44.16 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr6_+_30689350 44.01 ENST00000330914.3
tubulin, beta class I
chr1_-_222885770 43.44 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr1_-_51425902 43.12 ENST00000396153.2
Fas (TNFRSF6) associated factor 1
chr10_+_70883908 42.75 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
vacuolar protein sorting 26 homolog A (S. pombe)
chr20_+_48552908 42.05 ENST00000244061.2
ring finger protein 114
chr18_+_3247413 41.54 ENST00000579226.1
ENST00000217652.3
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_-_78148324 41.26 ENST00000370801.3
ENST00000433749.1
zinc finger, ZZ-type containing 3
chr7_+_100464760 39.84 ENST00000200457.4
thyroid hormone receptor interactor 6
chr15_-_72668805 39.25 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr21_-_38445470 38.71 ENST00000399098.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr11_+_63706444 38.66 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr6_-_43197189 38.59 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chrX_+_100663243 38.06 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_+_36562132 37.91 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chr7_-_99699538 37.80 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr12_-_56710118 37.68 ENST00000273308.4
canopy FGF signaling regulator 2
chr18_+_3247779 37.57 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr6_+_30689401 37.55 ENST00000396389.1
ENST00000396384.1
tubulin, beta class I
chr5_+_133707252 37.48 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr3_-_113465065 37.35 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_-_44223138 36.96 ENST00000260665.7
leucine-rich pentatricopeptide repeat containing
chr17_+_49230897 36.84 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chrX_+_23685563 36.49 ENST00000379341.4
peroxiredoxin 4
chr1_-_51425772 36.27 ENST00000371778.4
Fas (TNFRSF6) associated factor 1
chr19_+_12848299 35.99 ENST00000357332.3
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr1_-_155232221 35.83 ENST00000355379.3
secretory carrier membrane protein 3
chr20_+_31407692 35.75 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chr1_+_32479430 35.62 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chr8_+_98788003 35.44 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr2_-_10588630 35.34 ENST00000234111.4
ornithine decarboxylase 1
chr17_-_47492164 35.27 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
prohibitin
chr1_-_3816779 35.15 ENST00000361605.3
chromosome 1 open reading frame 174
chr8_+_55047763 35.14 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr14_+_35591928 35.06 ENST00000605870.1
ENST00000557404.3
KIAA0391
chr7_+_150759634 34.72 ENST00000392826.2
ENST00000461735.1
solute carrier family 4 (anion exchanger), member 2
chr12_+_72148614 34.65 ENST00000261263.3
RAB21, member RAS oncogene family
chr21_-_38445011 34.36 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_-_33385902 34.34 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr1_-_154600421 34.24 ENST00000368471.3
ENST00000292205.5
adenosine deaminase, RNA-specific
chr5_+_172410757 34.15 ENST00000519374.1
ENST00000519911.1
ENST00000265093.4
ENST00000517669.1
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr1_-_28559502 34.10 ENST00000263697.4
DnaJ (Hsp40) homolog, subfamily C, member 8
chr11_+_114310102 33.73 ENST00000265881.5
RNA exonuclease 2
chrX_+_48432892 33.66 ENST00000376759.3
ENST00000430348.2
RNA binding motif (RNP1, RRM) protein 3
chr2_-_26101374 33.65 ENST00000435504.4
additional sex combs like 2 (Drosophila)
chrX_+_48433326 33.34 ENST00000376755.1
RNA binding motif (RNP1, RRM) protein 3
chr1_+_42921761 32.93 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr17_-_7218403 32.76 ENST00000570780.1
G protein pathway suppressor 2
chr17_+_7476136 32.70 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr19_+_50180317 32.65 ENST00000534465.1
protein arginine methyltransferase 1
chr11_+_65770227 32.49 ENST00000527348.1
barrier to autointegration factor 1
chr5_+_159848854 32.37 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr16_+_88923494 32.29 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
trafficking protein particle complex 2-like
chr15_-_65281775 31.91 ENST00000433215.2
ENST00000558415.1
ENST00000557795.1
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr12_-_65153175 31.72 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
glucosamine (N-acetyl)-6-sulfatase
chr15_+_45315302 31.67 ENST00000267814.9
sorbitol dehydrogenase
chr12_+_57624085 31.48 ENST00000553474.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_155232047 31.24 ENST00000302631.3
secretory carrier membrane protein 3
chr3_-_195163803 31.19 ENST00000326793.6
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr12_+_56109926 31.13 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr3_+_140660743 31.12 ENST00000453248.2
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr2_+_113403434 31.12 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chrX_+_41192595 31.04 ENST00000399959.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr22_-_39096661 30.61 ENST00000216039.5
Josephin domain containing 1
chr1_-_110950564 30.45 ENST00000256644.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr19_+_41768401 30.24 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr10_+_112327425 30.00 ENST00000361804.4
structural maintenance of chromosomes 3
chrX_-_100872911 29.71 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
armadillo repeat containing, X-linked 6
chr1_+_43148625 29.60 ENST00000436427.1
Y box binding protein 1
chr21_-_38445443 29.51 ENST00000360525.4
phosphatidylinositol glycan anchor biosynthesis, class P
chr17_-_7137857 29.21 ENST00000005340.5
dishevelled segment polarity protein 2
chr14_-_35591433 28.91 ENST00000261475.5
ENST00000555644.1
protein phosphatase 2, regulatory subunit B'', gamma
chr21_-_38445297 28.87 ENST00000430792.1
ENST00000399103.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr22_+_20105259 28.78 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr12_-_76953573 28.71 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr1_-_8939265 28.51 ENST00000489867.1
enolase 1, (alpha)
chr1_-_68962805 28.40 ENST00000370966.5
DEP domain containing 1
chr7_+_73868220 28.14 ENST00000455841.2
GTF2I repeat domain containing 1
chr6_-_7313381 28.04 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr21_-_46238034 27.92 ENST00000332859.6
small ubiquitin-like modifier 3
chr11_+_114310164 27.85 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr11_-_61560254 27.71 ENST00000543510.1
transmembrane protein 258
chr3_+_33840050 27.65 ENST00000457054.2
ENST00000413073.1
programmed cell death 6 interacting protein
chr5_+_34656569 27.64 ENST00000428746.2
retinoic acid induced 14
chr11_+_114310237 27.62 ENST00000539119.1
RNA exonuclease 2
chr2_-_26101314 27.59 ENST00000336112.4
ENST00000272341.4
additional sex combs like 2 (Drosophila)
chr2_-_198299726 27.58 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
splicing factor 3b, subunit 1, 155kDa
chr1_-_39325431 27.57 ENST00000373001.3
Ras-related GTP binding C
chr12_-_76477707 27.54 ENST00000551992.1
nucleosome assembly protein 1-like 1
chr13_+_113951607 27.52 ENST00000397181.3
lysosomal-associated membrane protein 1
chr10_-_43903217 27.51 ENST00000357065.4
heterogeneous nuclear ribonucleoprotein F
chr11_-_122931881 27.43 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr12_+_57624119 27.37 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_13049413 27.11 ENST00000316448.5
ENST00000588454.1
calreticulin
chr4_-_2935674 27.11 ENST00000514800.1
major facilitator superfamily domain containing 10
chr19_-_4670345 26.96 ENST00000599630.1
ENST00000262947.3
chromosome 19 open reading frame 10
chr15_-_65282232 26.47 ENST00000416889.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr5_+_126112794 26.33 ENST00000261366.5
ENST00000395354.1
lamin B1
chr6_+_158589374 26.32 ENST00000607778.1
general transcription factor IIH, polypeptide 5
chr4_+_57302297 26.30 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr7_+_100271355 26.26 ENST00000436220.1
ENST00000424361.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr21_-_40720974 26.07 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr2_+_131100423 25.99 ENST00000409935.1
ENST00000409649.1
ENST00000428740.1
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr11_-_61560053 25.90 ENST00000537328.1
transmembrane protein 258
chr19_+_1275917 25.90 ENST00000469144.1
chromosome 19 open reading frame 24
chr19_-_8386238 25.81 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr3_+_133292851 25.70 ENST00000503932.1
CDV3 homolog (mouse)
chr8_+_22224760 25.39 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
solute carrier family 39 (zinc transporter), member 14
chrX_+_131157322 25.32 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr20_+_35202909 25.26 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr12_+_53645870 25.17 ENST00000329548.4
major facilitator superfamily domain containing 5
chr7_+_100271446 25.08 ENST00000419828.1
ENST00000427895.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_-_43638168 25.01 ENST00000431635.2
EBNA1 binding protein 2
chr2_+_198365095 24.95 ENST00000409468.1
heat shock 10kDa protein 1
chr17_+_49243639 24.93 ENST00000512737.1
ENST00000503064.1
NME1-NME2 readthrough
chr13_+_27998681 24.72 ENST00000381140.4
general transcription factor IIIA
chr1_+_26798955 24.68 ENST00000361427.5
high mobility group nucleosomal binding domain 2
chr5_+_34656331 24.68 ENST00000265109.3
retinoic acid induced 14
chr9_-_19127474 24.67 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
perilipin 2
chr15_-_65282274 24.37 ENST00000204566.2
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr9_+_117350009 24.30 ENST00000374050.3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr12_+_104359576 24.23 ENST00000392872.3
ENST00000436021.2
thymine-DNA glycosylase
chr14_-_54955721 24.20 ENST00000554908.1
glia maturation factor, beta
chr19_+_50180507 24.10 ENST00000454376.2
ENST00000524771.1
protein arginine methyltransferase 1
chr3_+_127323739 24.04 ENST00000491422.1
minichromosome maintenance complex component 2
chr8_-_144679296 24.04 ENST00000317198.6
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr18_+_12947981 23.59 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr2_-_98612350 23.57 ENST00000186436.5
transmembrane protein 131
chr7_+_150065879 23.57 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
replication initiator 1
zinc finger protein 775
chr19_+_1067271 23.50 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr3_+_52719936 23.45 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr21_-_46237959 23.23 ENST00000397898.3
ENST00000411651.2
small ubiquitin-like modifier 3
chr8_+_22224811 23.16 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr12_+_57623869 22.83 ENST00000414700.3
ENST00000557703.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr20_-_61847586 22.83 ENST00000370339.3
YTH domain family, member 1
chr4_-_83295103 22.79 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr7_+_12726474 22.73 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ADP-ribosylation factor-like 4A
chr15_+_75628394 22.65 ENST00000564815.1
ENST00000338995.6
COMM domain containing 4
chr5_+_133706865 22.63 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chr4_-_54930790 22.57 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr11_-_85779971 22.47 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chr19_+_10765003 22.42 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr11_-_64013663 22.34 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_+_131157290 22.33 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr15_+_75628232 22.32 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4
chr15_+_44084503 22.25 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr10_-_99258135 22.19 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr10_+_75910960 22.18 ENST00000539909.1
ENST00000286621.2
adenosine kinase
chr10_+_81107271 22.15 ENST00000448165.1
peptidylprolyl isomerase F
chr17_+_30677136 21.99 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
zinc finger protein 207
chr19_-_10530784 21.99 ENST00000593124.1
cell division cycle 37
chr10_+_124913930 21.95 ENST00000368858.5
BUB3 mitotic checkpoint protein
chr21_-_40720995 21.95 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr19_+_797443 21.88 ENST00000394601.4
ENST00000589575.1
polypyrimidine tract binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MAX_TFEB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
119.6 598.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
42.5 169.9 GO:0046452 dihydrofolate metabolic process(GO:0046452)
27.9 111.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
22.0 66.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
20.0 60.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
19.8 178.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
17.5 122.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
17.1 85.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
16.8 50.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
15.2 45.7 GO:0090149 mitochondrial membrane fission(GO:0090149)
14.9 44.7 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
14.7 132.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
14.6 43.8 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
14.4 57.6 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
13.8 27.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
13.7 41.0 GO:0044209 AMP salvage(GO:0044209)
13.6 54.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
12.9 51.7 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
12.8 38.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
12.4 61.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
12.4 74.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
11.9 35.8 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
11.9 35.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
11.4 34.2 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
10.6 31.7 GO:0006059 hexitol metabolic process(GO:0006059)
10.5 63.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
10.5 104.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
10.5 83.8 GO:0016139 glycoside catabolic process(GO:0016139)
10.4 10.4 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
10.3 31.0 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
10.0 10.0 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
9.9 79.2 GO:0060155 platelet dense granule organization(GO:0060155)
9.8 98.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
9.8 39.1 GO:0006218 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
9.8 48.8 GO:0042256 mature ribosome assembly(GO:0042256)
9.7 48.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
9.6 28.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
9.3 27.9 GO:0061470 T follicular helper cell differentiation(GO:0061470)
9.2 36.6 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
9.1 54.7 GO:2000323 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
8.9 35.6 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
8.1 24.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
8.0 39.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
7.9 15.9 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
7.6 22.8 GO:1901355 response to rapamycin(GO:1901355)
7.3 66.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
7.3 51.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
7.2 7.2 GO:0016071 mRNA metabolic process(GO:0016071)
7.1 49.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
7.0 34.8 GO:0006344 maintenance of chromatin silencing(GO:0006344)
6.9 61.8 GO:1902903 regulation of fibril organization(GO:1902903)
6.8 47.9 GO:1902570 protein localization to nucleolus(GO:1902570)
6.8 20.4 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
6.6 79.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
6.6 131.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
6.3 50.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
6.2 24.6 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
6.0 23.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
6.0 185.6 GO:0090383 phagosome acidification(GO:0090383)
5.9 29.5 GO:0016321 female meiosis chromosome segregation(GO:0016321)
5.8 58.5 GO:0021769 orbitofrontal cortex development(GO:0021769)
5.8 57.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
5.6 16.7 GO:0006166 purine ribonucleoside salvage(GO:0006166)
5.6 61.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
5.3 21.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
5.1 51.0 GO:0015074 DNA integration(GO:0015074)
5.1 35.5 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
5.0 15.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
5.0 15.0 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
4.9 9.8 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
4.8 19.3 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
4.8 19.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
4.7 37.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
4.6 13.8 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
4.5 27.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
4.4 17.8 GO:0048254 snoRNA localization(GO:0048254)
4.4 13.3 GO:0072711 cellular response to hydroxyurea(GO:0072711)
4.4 48.8 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
4.4 44.2 GO:0018202 peptidyl-histidine modification(GO:0018202)
4.2 29.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
4.2 21.1 GO:0006740 NADPH regeneration(GO:0006740)
4.2 50.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
4.1 20.7 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
4.0 15.8 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
3.9 39.4 GO:0045008 depyrimidination(GO:0045008)
3.9 11.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
3.8 42.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
3.8 11.5 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
3.8 188.9 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
3.8 15.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
3.7 11.2 GO:0005997 xylulose metabolic process(GO:0005997)
3.6 28.9 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
3.5 10.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
3.5 21.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
3.5 31.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
3.5 24.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
3.4 10.3 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
3.4 20.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
3.4 44.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
3.3 19.9 GO:0015866 adenine transport(GO:0015853) ADP transport(GO:0015866) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
3.3 33.1 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
3.3 36.1 GO:0030043 actin filament fragmentation(GO:0030043)
3.3 9.8 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
3.3 13.1 GO:0002572 pro-T cell differentiation(GO:0002572)
3.2 189.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
3.2 9.5 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
3.2 9.5 GO:0010587 miRNA catabolic process(GO:0010587)
3.1 9.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
3.1 12.5 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
3.1 9.4 GO:0006014 D-ribose metabolic process(GO:0006014)
3.1 15.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
3.1 9.2 GO:0022604 regulation of cell morphogenesis(GO:0022604)
3.0 18.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
3.0 9.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
3.0 30.3 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
3.0 15.1 GO:0019348 dolichol metabolic process(GO:0019348)
3.0 9.0 GO:0072719 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) cellular response to cisplatin(GO:0072719)
3.0 30.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
2.9 14.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
2.9 14.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.9 8.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
2.8 8.5 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
2.8 19.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.8 16.7 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
2.8 11.0 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
2.7 59.6 GO:0030488 tRNA methylation(GO:0030488)
2.7 10.6 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
2.7 18.6 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
2.6 34.1 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.6 101.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
2.6 38.6 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
2.6 23.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
2.6 5.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
2.5 89.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
2.5 5.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
2.5 12.6 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
2.5 12.6 GO:0006041 glucosamine metabolic process(GO:0006041)
2.5 47.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
2.5 7.4 GO:0051684 maintenance of Golgi location(GO:0051684)
2.4 7.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
2.4 7.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
2.4 14.4 GO:0050685 positive regulation of mRNA processing(GO:0050685)
2.4 7.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
2.4 11.8 GO:0016240 autophagosome docking(GO:0016240)
2.4 4.7 GO:0019087 transformation of host cell by virus(GO:0019087)
2.4 49.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
2.3 15.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
2.3 72.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
2.2 6.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.2 8.9 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
2.2 15.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.1 15.0 GO:0090160 Golgi to lysosome transport(GO:0090160)
2.1 66.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
2.1 10.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.1 12.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
2.1 6.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
2.1 10.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
2.1 27.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
2.1 10.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
2.1 8.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
2.0 6.0 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
2.0 139.2 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
2.0 43.0 GO:0006337 nucleosome disassembly(GO:0006337)
1.9 5.8 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.9 15.3 GO:0044351 macropinocytosis(GO:0044351)
1.9 17.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
1.9 49.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.9 17.1 GO:0051451 myoblast migration(GO:0051451)
1.9 5.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498) positive regulation of protein autoubiquitination(GO:1902499)
1.9 39.4 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.9 31.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
1.9 16.9 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
1.9 29.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
1.9 33.5 GO:0097502 mannosylation(GO:0097502)
1.9 7.4 GO:0072553 terminal button organization(GO:0072553)
1.8 74.0 GO:0097421 liver regeneration(GO:0097421)
1.8 31.2 GO:0036010 protein localization to endosome(GO:0036010)
1.8 7.3 GO:0043335 protein unfolding(GO:0043335)
1.8 12.7 GO:0015936 coenzyme A metabolic process(GO:0015936)
1.8 7.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
1.8 10.6 GO:0006689 ganglioside catabolic process(GO:0006689)
1.8 21.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
1.7 10.2 GO:0032328 alanine transport(GO:0032328)
1.7 30.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
1.7 18.5 GO:0033572 transferrin transport(GO:0033572)
1.7 5.0 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
1.6 9.8 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.6 16.1 GO:0006983 ER overload response(GO:0006983)
1.6 62.7 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
1.6 8.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.6 9.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.6 53.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.5 4.6 GO:0051661 maintenance of centrosome location(GO:0051661)
1.5 18.4 GO:0007379 segment specification(GO:0007379)
1.5 18.4 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
1.5 42.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
1.5 22.6 GO:0038092 nodal signaling pathway(GO:0038092)
1.5 16.3 GO:0090161 Golgi ribbon formation(GO:0090161)
1.5 4.4 GO:0032986 protein-DNA complex disassembly(GO:0032986)
1.5 4.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.4 10.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.4 20.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.4 12.9 GO:0051382 kinetochore assembly(GO:0051382)
1.4 22.9 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
1.4 7.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
1.4 102.4 GO:0006342 chromatin silencing(GO:0006342)
1.4 303.7 GO:0006364 rRNA processing(GO:0006364)
1.4 20.5 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
1.4 13.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
1.4 9.5 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.3 8.1 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
1.3 9.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.3 14.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
1.3 9.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
1.3 81.6 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
1.3 12.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.2 6.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.2 22.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.2 22.0 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
1.2 7.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.2 22.7 GO:0031639 plasminogen activation(GO:0031639)
1.2 45.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
1.2 9.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
1.1 10.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.1 22.8 GO:0045948 positive regulation of translational initiation(GO:0045948)
1.1 1.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.1 76.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
1.1 8.9 GO:0048752 semicircular canal morphogenesis(GO:0048752)
1.1 4.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
1.1 24.0 GO:0009303 rRNA transcription(GO:0009303)
1.1 3.2 GO:0015680 intracellular copper ion transport(GO:0015680)
1.1 1.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
1.1 3.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.0 15.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
1.0 9.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
1.0 30.7 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
1.0 2.0 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.0 12.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
1.0 85.7 GO:0070527 platelet aggregation(GO:0070527)
1.0 5.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.9 19.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.9 24.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.9 6.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.9 35.3 GO:1901998 toxin transport(GO:1901998)
0.9 81.8 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.9 14.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.9 4.4 GO:0007498 mesoderm development(GO:0007498)
0.9 8.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.8 20.3 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.8 38.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.8 47.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.8 87.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.8 23.5 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter(GO:0060260)
0.8 47.4 GO:0031100 organ regeneration(GO:0031100)
0.8 25.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.8 5.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.7 11.2 GO:0000338 protein deneddylation(GO:0000338)
0.7 5.9 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.7 2.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.7 8.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.7 8.0 GO:0051601 exocyst localization(GO:0051601)
0.7 10.7 GO:0006265 DNA topological change(GO:0006265)
0.7 3.4 GO:0050957 equilibrioception(GO:0050957)
0.7 7.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.7 30.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.7 67.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.7 15.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.7 14.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.7 4.6 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.6 3.1 GO:0009650 UV protection(GO:0009650)
0.6 140.7 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.6 16.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.6 4.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.6 1.8 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.6 3.0 GO:0006824 cobalt ion transport(GO:0006824)
0.6 41.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.6 183.7 GO:0010038 response to metal ion(GO:0010038)
0.5 41.9 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.5 2.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.5 5.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.5 9.5 GO:0002021 response to dietary excess(GO:0002021)
0.5 33.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.5 7.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.5 2.5 GO:1901490 positive regulation of mast cell chemotaxis(GO:0060754) regulation of lymphangiogenesis(GO:1901490)
0.5 3.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 1.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.5 6.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 10.3 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.5 23.3 GO:0015701 bicarbonate transport(GO:0015701)
0.5 24.7 GO:0019915 lipid storage(GO:0019915)
0.5 2.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.4 1.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4 5.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.4 67.6 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.4 3.9 GO:1904350 regulation of protein catabolic process in the vacuole(GO:1904350)
0.4 48.2 GO:0006414 translational elongation(GO:0006414)
0.4 35.5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.4 26.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.4 8.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.4 4.6 GO:0050872 white fat cell differentiation(GO:0050872)
0.4 18.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.4 3.5 GO:0007010 cytoskeleton organization(GO:0007010)
0.4 11.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.4 1.2 GO:0070459 prolactin secretion(GO:0070459)
0.4 8.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.4 4.6 GO:0001778 plasma membrane repair(GO:0001778)
0.4 9.0 GO:1902583 intracellular transport of virus(GO:0075733) multi-organism intracellular transport(GO:1902583)
0.4 8.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.4 1.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.4 1.8 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.4 4.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 1.1 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617)
0.3 10.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.3 7.7 GO:0070207 protein homotrimerization(GO:0070207)
0.3 9.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.3 15.1 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.3 21.8 GO:0006334 nucleosome assembly(GO:0006334)
0.3 8.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.3 4.5 GO:0006020 inositol metabolic process(GO:0006020)
0.3 8.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.3 1.8 GO:1904062 regulation of calcium ion transmembrane transport(GO:1903169) regulation of cation transmembrane transport(GO:1904062)
0.3 4.6 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.3 2.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.3 6.6 GO:0006400 tRNA modification(GO:0006400)
0.3 2.3 GO:0010628 positive regulation of gene expression(GO:0010628)
0.2 5.5 GO:0007015 actin filament organization(GO:0007015)
0.2 4.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 11.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 2.2 GO:0007219 Notch signaling pathway(GO:0007219)
0.2 2.6 GO:0007588 excretion(GO:0007588)
0.2 3.5 GO:0003334 keratinocyte development(GO:0003334)
0.2 4.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.2 3.3 GO:0034453 microtubule anchoring(GO:0034453)
0.2 2.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 1.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.6 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.2 4.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.7 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
0.1 3.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 2.3 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.3 GO:0016180 snRNA processing(GO:0016180)
0.1 3.1 GO:0010608 posttranscriptional regulation of gene expression(GO:0010608)
0.1 2.1 GO:0060009 Sertoli cell development(GO:0060009)
0.1 4.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.9 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 6.7 GO:0006401 RNA catabolic process(GO:0006401)
0.1 2.0 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 3.1 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 1.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 12.4 GO:0031424 keratinization(GO:0031424)
0.1 3.1 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.4 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.1 3.0 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.1 1.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 5.9 GO:2001234 negative regulation of apoptotic signaling pathway(GO:2001234)
0.1 2.0 GO:0033198 response to ATP(GO:0033198)
0.1 4.6 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.9 GO:0007100 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.1 4.3 GO:0042246 tissue regeneration(GO:0042246)
0.1 4.2 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.1 0.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 2.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 7.5 GO:0060041 retina development in camera-type eye(GO:0060041)
0.1 2.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 1.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 10.3 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 3.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 4.7 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 9.0 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.3 GO:1903364 positive regulation of cellular protein catabolic process(GO:1903364)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0043585 nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0 0.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.1 GO:0050821 protein stabilization(GO:0050821)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
99.7 598.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
28.2 197.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
24.6 98.3 GO:0033186 CAF-1 complex(GO:0033186)
22.3 156.3 GO:0046581 intercellular canaliculus(GO:0046581)
17.4 104.3 GO:0001740 Barr body(GO:0001740)
13.1 131.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
12.8 51.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
12.6 63.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
12.6 100.9 GO:0070552 BRISC complex(GO:0070552)
12.1 36.4 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
12.0 60.1 GO:0033503 HULC complex(GO:0033503)
11.2 67.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
11.0 44.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
10.5 83.8 GO:0042382 paraspeckles(GO:0042382)
10.5 94.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
10.2 30.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
10.0 30.0 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
9.0 45.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
9.0 44.9 GO:0071986 Ragulator complex(GO:0071986)
8.9 80.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
8.4 67.6 GO:0097208 alveolar lamellar body(GO:0097208)
8.4 109.3 GO:0042555 MCM complex(GO:0042555)
8.3 33.1 GO:0070985 TFIIK complex(GO:0070985)
8.3 123.8 GO:0005641 nuclear envelope lumen(GO:0005641)
8.1 48.5 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
8.0 23.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
8.0 39.8 GO:0045323 interleukin-1 receptor complex(GO:0045323)
7.6 38.2 GO:0034457 Mpp10 complex(GO:0034457)
7.4 67.0 GO:0000439 core TFIIH complex(GO:0000439)
7.4 44.2 GO:0030905 retromer, tubulation complex(GO:0030905)
7.3 80.5 GO:0033391 chromatoid body(GO:0033391)
7.1 35.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
7.0 42.1 GO:0071817 MMXD complex(GO:0071817)
6.8 34.2 GO:0044530 supraspliceosomal complex(GO:0044530)
6.5 32.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
6.4 89.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
6.0 35.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
5.6 16.7 GO:0097447 dendritic tree(GO:0097447)
5.3 37.3 GO:0031415 NatA complex(GO:0031415)
5.0 15.0 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
4.6 82.5 GO:0031083 BLOC-1 complex(GO:0031083)
4.5 81.1 GO:0034709 methylosome(GO:0034709)
4.5 53.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
4.4 43.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
4.4 21.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
4.2 29.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
4.1 16.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
4.1 73.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
4.0 32.2 GO:1990111 spermatoproteasome complex(GO:1990111)
3.9 19.6 GO:0016589 NURF complex(GO:0016589)
3.9 31.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
3.7 147.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
3.6 10.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
3.5 10.6 GO:0005960 glycine cleavage complex(GO:0005960)
3.5 34.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
3.4 20.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
3.4 16.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.4 23.6 GO:0061700 GATOR2 complex(GO:0061700)
3.3 13.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
3.3 112.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
3.2 12.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
3.0 24.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
2.9 55.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.9 17.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.9 42.9 GO:0090543 Flemming body(GO:0090543)
2.8 34.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
2.7 13.6 GO:0005899 insulin receptor complex(GO:0005899)
2.6 10.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.6 23.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
2.6 7.7 GO:0005879 axonemal microtubule(GO:0005879)
2.6 40.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
2.5 12.7 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
2.4 14.7