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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MEIS1

Z-value: 1.04

Motif logo

Transcription factors associated with MEIS1

Gene Symbol Gene ID Gene Info
ENSG00000143995.15 Meis homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEIS1hg19_v2_chr2_+_66662690_66662711-0.134.9e-02Click!

Activity profile of MEIS1 motif

Sorted Z-values of MEIS1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_183892635 11.03 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
adaptor-related protein complex 2, mu 1 subunit
chr17_-_29648761 10.80 ENST00000247270.3
ENST00000462804.2
ecotropic viral integration site 2A
chr10_+_54074033 10.01 ENST00000373970.3
dickkopf WNT signaling pathway inhibitor 1
chr2_+_201170770 9.27 ENST00000409988.3
ENST00000409385.1
spermatogenesis associated, serine-rich 2-like
chr1_-_113247543 9.22 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr3_+_159570722 9.11 ENST00000482804.1
schwannomin interacting protein 1
chr1_+_26605618 8.72 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr16_+_75600247 8.67 ENST00000037243.2
ENST00000565057.1
ENST00000563744.1
GABA(A) receptor-associated protein-like 2
chr11_+_35198243 8.51 ENST00000528455.1
CD44 molecule (Indian blood group)
chr4_+_88896819 7.91 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr2_+_201936707 7.89 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr5_-_175843569 7.81 ENST00000310418.4
ENST00000345807.2
clathrin, light chain B
chr12_-_56694142 7.77 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chr8_-_120651020 7.41 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr3_-_49066811 6.87 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr1_+_169079823 6.81 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr20_+_44036900 6.63 ENST00000443296.1
dysbindin (dystrobrevin binding protein 1) domain containing 2
chrX_+_118602363 6.62 ENST00000317881.8
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr17_+_49243176 6.57 ENST00000513177.1
NME1-NME2 readthrough
chr1_+_87797351 6.44 ENST00000370542.1
LIM domain only 4
chr2_-_175870085 6.38 ENST00000409156.3
chimerin 1
chr8_-_54755459 6.28 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr8_-_54755789 6.27 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr1_+_155657737 6.26 ENST00000471642.2
ENST00000471214.1
death associated protein 3
chr11_-_122929699 6.17 ENST00000526686.1
heat shock 70kDa protein 8
chr3_-_127541194 6.13 ENST00000453507.2
monoglyceride lipase
chrX_-_13835461 6.10 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr22_-_43355858 6.04 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
protein kinase C and casein kinase substrate in neurons 2
chr12_-_118498958 5.91 ENST00000315436.3
WD repeat and SOCS box containing 2
chr7_+_98923505 5.89 ENST00000432884.2
ENST00000262942.5
actin related protein 2/3 complex, subunit 1A, 41kDa
chr1_+_165796753 5.78 ENST00000367879.4
uridine-cytidine kinase 2
chr7_+_149571045 5.73 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATPase, H+ transporting V0 subunit e2
chr3_+_158787041 5.60 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chrX_+_51636629 5.60 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
melanoma antigen family D, 1
chr2_-_170681324 5.58 ENST00000409340.1
methyltransferase like 5
chr11_-_64052111 5.57 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BCL2-associated agonist of cell death
chr18_-_21891460 5.57 ENST00000357041.4
oxysterol binding protein-like 1A
chr16_+_31044413 5.54 ENST00000394998.1
syntaxin 4
chr5_+_49962495 5.51 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr16_+_4674814 5.49 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr1_+_156163880 5.49 ENST00000359511.4
ENST00000423538.2
solute carrier family 25, member 44
chr17_-_79481666 5.46 ENST00000575659.1
actin, gamma 1
chr19_-_47353547 5.42 ENST00000601498.1
adaptor-related protein complex 2, sigma 1 subunit
chr2_+_172544294 5.41 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
dynein, cytoplasmic 1, intermediate chain 2
chr1_+_10271674 5.41 ENST00000377086.1
kinesin family member 1B
chr16_-_67493110 5.36 ENST00000602876.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr1_+_171810606 5.32 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
dynamin 3
chr16_+_31044812 5.30 ENST00000313843.3
syntaxin 4
chr8_+_11666649 5.26 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr6_+_63921351 5.24 ENST00000370659.1
FK506 binding protein 1C
chr12_-_76462713 5.24 ENST00000552056.1
nucleosome assembly protein 1-like 1
chr12_-_118810688 5.23 ENST00000542532.1
ENST00000392533.3
TAO kinase 3
chr3_-_47934234 5.23 ENST00000420772.2
microtubule-associated protein 4
chr2_+_201170596 5.10 ENST00000439084.1
ENST00000409718.1
spermatogenesis associated, serine-rich 2-like
chr5_+_92919043 4.90 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr6_+_39760783 4.90 ENST00000398904.2
ENST00000538976.1
dishevelled associated activator of morphogenesis 2
chr12_-_123756781 4.83 ENST00000544658.1
cyclin-dependent kinase 2 associated protein 1
chr15_-_34394008 4.83 ENST00000527822.1
ENST00000528949.1
ER membrane protein complex subunit 7
chr16_+_14927538 4.79 ENST00000287667.7
NODAL modulator 1
chrX_-_92928557 4.74 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr5_-_175843524 4.70 ENST00000502877.1
clathrin, light chain B
chr17_+_1944790 4.70 ENST00000575162.1
diphthamide biosynthesis 1
chr12_+_79439405 4.64 ENST00000552744.1
synaptotagmin I
chr9_-_124922021 4.61 ENST00000537618.1
ENST00000373768.3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr1_-_155211017 4.59 ENST00000536770.1
ENST00000368373.3
glucosidase, beta, acid
chr11_+_35198118 4.59 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44 molecule (Indian blood group)
chr13_-_67802549 4.59 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr1_-_154909329 4.58 ENST00000368467.3
phosphomevalonate kinase
chr8_-_102216925 4.58 ENST00000517844.1
zinc finger protein 706
chr17_+_38137050 4.52 ENST00000264639.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr14_+_90722839 4.50 ENST00000261303.8
ENST00000553835.1
proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr11_+_35211429 4.47 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44 molecule (Indian blood group)
chr22_-_39096661 4.45 ENST00000216039.5
Josephin domain containing 1
chr3_-_58419537 4.42 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
pyruvate dehydrogenase (lipoamide) beta
chr14_-_58893832 4.39 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chrX_+_155110956 4.38 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr14_+_104029278 4.37 ENST00000472726.2
ENST00000409074.2
ENST00000440963.1
ENST00000556253.2
ENST00000247618.4
Kinesin light chain 1
apoptogenic 1, mitochondrial
chr17_-_76899275 4.35 ENST00000322630.2
ENST00000586713.1
Protein DDC8 homolog
chr17_+_38137073 4.30 ENST00000541736.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr14_+_58666824 4.29 ENST00000254286.4
actin-related protein 10 homolog (S. cerevisiae)
chr8_+_61429728 4.28 ENST00000529579.1
RAB2A, member RAS oncogene family
chr2_-_2334888 4.27 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr6_-_46293378 4.25 ENST00000330430.6
regulator of calcineurin 2
chr11_+_35211511 4.24 ENST00000524922.1
CD44 molecule (Indian blood group)
chr6_-_75960024 4.23 ENST00000370081.2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr6_-_33385854 4.23 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr9_+_71820057 4.23 ENST00000539225.1
tight junction protein 2
chr18_+_3449695 4.21 ENST00000343820.5
TGFB-induced factor homeobox 1
chr4_-_102268628 4.21 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
protein phosphatase 3, catalytic subunit, alpha isozyme
chr15_-_34394119 4.21 ENST00000256545.4
ER membrane protein complex subunit 7
chr5_+_122110691 4.20 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr9_+_71819927 4.19 ENST00000535702.1
tight junction protein 2
chr2_+_219081817 4.13 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
actin related protein 2/3 complex, subunit 2, 34kDa
chr8_-_120685608 4.13 ENST00000427067.2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr17_-_53809473 4.10 ENST00000575734.1
transmembrane protein 100
chr1_-_161087802 4.09 ENST00000368010.3
prefoldin subunit 2
chr4_+_41614909 4.01 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr22_+_41258250 3.97 ENST00000544094.1
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr14_+_24540731 3.97 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
copine VI (neuronal)
chr2_+_102456277 3.96 ENST00000421882.1
mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_47082408 3.95 ENST00000518022.1
ENST00000276052.6
cyclin-dependent kinase 16
chr5_+_140864649 3.94 ENST00000306593.1
protocadherin gamma subfamily C, 4
chr12_+_12870055 3.94 ENST00000228872.4
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr14_+_24540046 3.92 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
copine VI (neuronal)
chrX_+_70503037 3.91 ENST00000535149.1
non-POU domain containing, octamer-binding
chr5_+_125758865 3.91 ENST00000542322.1
ENST00000544396.1
GRAM domain containing 3
chr8_-_141931287 3.89 ENST00000517887.1
protein tyrosine kinase 2
chr12_+_19358228 3.88 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr11_-_31832862 3.88 ENST00000379115.4
paired box 6
chr8_-_18744528 3.87 ENST00000523619.1
pleckstrin and Sec7 domain containing 3
chr15_+_80364901 3.82 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr5_+_125758813 3.75 ENST00000285689.3
ENST00000515200.1
GRAM domain containing 3
chr20_+_4666882 3.75 ENST00000379440.4
ENST00000430350.2
prion protein
chr11_-_31832785 3.74 ENST00000241001.8
paired box 6
chr5_+_32585605 3.72 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1 homolog (S. cerevisiae)
chr3_+_35722487 3.71 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr7_+_95401851 3.70 ENST00000447467.2
dynein, cytoplasmic 1, intermediate chain 1
chr7_+_94285637 3.69 ENST00000482108.1
ENST00000488574.1
paternally expressed 10
chr6_+_30297306 3.69 ENST00000420746.1
ENST00000513556.1
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr11_+_71938925 3.66 ENST00000538751.1
inositol polyphosphate phosphatase-like 1
chr6_-_33385655 3.66 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr17_-_685493 3.62 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
glyoxalase domain containing 4
chr3_+_184033135 3.61 ENST00000424196.1
eukaryotic translation initiation factor 4 gamma, 1
chr15_-_37390482 3.61 ENST00000559085.1
ENST00000397624.3
Meis homeobox 2
chr3_-_12705600 3.60 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
v-raf-1 murine leukemia viral oncogene homolog 1
chr5_-_150466692 3.60 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNFAIP3 interacting protein 1
chr6_+_111195973 3.58 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
adenosylmethionine decarboxylase 1
chr1_-_43638168 3.56 ENST00000431635.2
EBNA1 binding protein 2
chr12_-_123756687 3.56 ENST00000261692.2
cyclin-dependent kinase 2 associated protein 1
chr15_-_37392086 3.53 ENST00000561208.1
Meis homeobox 2
chr12_-_76953573 3.53 ENST00000549646.1
ENST00000550628.1
ENST00000553139.1
ENST00000261183.3
ENST00000393250.4
oxysterol binding protein-like 8
chr1_-_193075180 3.50 ENST00000367440.3
glutaredoxin 2
chr17_+_66245341 3.49 ENST00000577985.1
archaelysin family metallopeptidase 2
chrX_+_150148976 3.48 ENST00000419110.1
high mobility group box 3
chr4_-_102268484 3.47 ENST00000394853.4
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_127541679 3.46 ENST00000265052.5
monoglyceride lipase
chr5_+_140810132 3.45 ENST00000252085.3
protocadherin gamma subfamily A, 12
chr11_+_4116054 3.45 ENST00000423050.2
ribonucleotide reductase M1
chr3_+_130569429 3.44 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr20_+_36405665 3.41 ENST00000373469.1
catenin, beta like 1
chr2_-_220119280 3.40 ENST00000392088.2
tubulin, alpha 4a
chr14_+_24701819 3.39 ENST00000560139.1
ENST00000559910.1
guanosine monophosphate reductase 2
chr3_-_58613323 3.36 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr11_+_65686952 3.34 ENST00000527119.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr14_+_90722886 3.32 ENST00000543772.2
proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr16_+_4674787 3.32 ENST00000262370.7
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr22_+_42017987 3.31 ENST00000405506.1
X-ray repair complementing defective repair in Chinese hamster cells 6
chr12_+_28410128 3.31 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr1_+_15736359 3.27 ENST00000375980.4
EF-hand domain family, member D2
chr3_+_130569592 3.25 ENST00000533801.2
ATPase, Ca++ transporting, type 2C, member 1
chr16_-_67514982 3.24 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr17_-_39684550 3.23 ENST00000455635.1
ENST00000361566.3
keratin 19
chrX_-_47004437 3.22 ENST00000276062.8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr16_-_66968055 3.19 ENST00000568572.1
family with sequence similarity 96, member B
chr11_-_31832581 3.16 ENST00000379111.2
paired box 6
chr17_-_685559 3.13 ENST00000301329.6
glyoxalase domain containing 4
chr9_+_87285539 3.11 ENST00000359847.3
neurotrophic tyrosine kinase, receptor, type 2
chr18_+_3449821 3.11 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr14_-_102552659 3.09 ENST00000441629.2
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr20_+_33104199 3.09 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
dynein, light chain, roadblock-type 1
chr16_-_18573396 3.09 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NODAL modulator 2
chr2_-_98280383 3.08 ENST00000289228.5
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr6_-_84418860 3.07 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr4_-_100871506 3.06 ENST00000296417.5
H2A histone family, member Z
chr12_+_113344755 3.05 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr17_-_73389854 3.05 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
growth factor receptor-bound protein 2
chr14_-_71107921 3.03 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr1_-_21948906 3.02 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr1_+_40506392 3.02 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr11_+_74660278 3.02 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_-_155211065 3.02 ENST00000427500.3
glucosidase, beta, acid
chr6_-_33385823 3.01 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr1_-_201476274 3.00 ENST00000340006.2
cysteine and glycine-rich protein 1
chr11_+_4116005 3.00 ENST00000300738.5
ribonucleotide reductase M1
chr7_-_102213030 2.99 ENST00000511313.1
ENST00000513438.1
ENST00000513506.1
polymerase (RNA) II (DNA directed) polypeptide J3
chr12_+_75874460 2.98 ENST00000266659.3
GLI pathogenesis-related 1
chr10_+_114709999 2.97 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_-_103876965 2.96 ENST00000337198.5
antizyme inhibitor 1
chr7_-_102119342 2.96 ENST00000393794.3
ENST00000292614.5
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr6_-_84418841 2.95 ENST00000369694.2
ENST00000195649.6
synaptosomal-associated protein, 91kDa
chr6_-_41909191 2.94 ENST00000512426.1
ENST00000372987.4
cyclin D3
chr2_-_56150910 2.93 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EGF containing fibulin-like extracellular matrix protein 1
chr18_+_3451584 2.93 ENST00000551541.1
TGFB-induced factor homeobox 1
chr16_+_56691838 2.92 ENST00000394501.2
metallothionein 1F
chr1_+_244214577 2.91 ENST00000358704.4
zinc finger and BTB domain containing 18
chr16_+_56691606 2.91 ENST00000334350.6
metallothionein 1F
chr17_-_73150599 2.91 ENST00000392566.2
ENST00000581874.1
hematological and neurological expressed 1
chr12_+_8234807 2.91 ENST00000339754.5
NECAP endocytosis associated 1
chr11_-_36310958 2.91 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMM domain containing 9
chr7_-_137028534 2.90 ENST00000348225.2
pleiotrophin
chr8_-_13372395 2.90 ENST00000276297.4
ENST00000511869.1
deleted in liver cancer 1
chr16_+_56691911 2.89 ENST00000568475.1
metallothionein 1F
chr9_-_136004782 2.88 ENST00000393157.3
ral guanine nucleotide dissociation stimulator
chr14_+_23340822 2.88 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr7_-_137028498 2.88 ENST00000393083.2
pleiotrophin
chr5_-_176057365 2.85 ENST00000310112.3
synuclein, beta
chr19_-_43702231 2.83 ENST00000597374.1
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr10_-_75012360 2.83 ENST00000416782.2
ENST00000372945.3
ENST00000372940.3
mitochondrial ribosomal protein S16
chr2_+_201173667 2.80 ENST00000409755.3
spermatogenesis associated, serine-rich 2-like
chr17_-_73389737 2.79 ENST00000392563.1
growth factor receptor-bound protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
3.3 10.0 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
2.7 13.6 GO:0003322 pancreatic A cell development(GO:0003322)
2.6 7.9 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
2.6 20.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.6 7.7 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
2.0 11.9 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.9 5.8 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
1.9 5.7 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.9 7.6 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
1.8 5.4 GO:1904647 response to rotenone(GO:1904647)
1.8 5.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.7 6.8 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
1.5 4.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.5 4.6 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.5 4.4 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
1.4 5.8 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
1.4 5.6 GO:0052330 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of type B pancreatic cell development(GO:2000078)
1.4 1.4 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
1.4 9.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.3 8.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.3 1.3 GO:0006097 glyoxylate cycle(GO:0006097)
1.3 6.6 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.2 6.2 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.2 3.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
1.2 3.6 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.2 13.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.2 3.6 GO:0006597 spermine biosynthetic process(GO:0006597)
1.1 6.9 GO:0006177 GMP biosynthetic process(GO:0006177)
1.1 6.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
1.1 7.8 GO:0016129 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
1.1 3.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.1 3.3 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
1.0 3.0 GO:0006172 ADP biosynthetic process(GO:0006172)
1.0 4.0 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
1.0 3.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
1.0 9.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
1.0 4.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.0 11.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.0 3.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.9 4.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.9 3.8 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.9 16.9 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.9 5.2 GO:0051012 microtubule sliding(GO:0051012)
0.9 8.7 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.8 28.7 GO:0090383 phagosome acidification(GO:0090383)
0.8 14.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.8 4.9 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.8 2.4 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.8 4.0 GO:0006740 NADPH regeneration(GO:0006740)
0.8 5.6 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.8 2.4 GO:0046680 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.8 2.4 GO:0098923 NMDA glutamate receptor clustering(GO:0097114) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.8 3.1 GO:0043335 protein unfolding(GO:0043335)
0.8 6.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.8 6.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.7 3.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.7 2.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.7 10.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.7 2.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.7 2.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.7 2.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.7 2.1 GO:0031627 telomeric loop formation(GO:0031627) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.7 2.8 GO:2000035 regulation of stem cell division(GO:2000035)
0.7 6.1 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.7 2.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7 2.7 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.7 1.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.7 2.0 GO:0019417 sulfur oxidation(GO:0019417)
0.6 1.9 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.6 1.9 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.6 1.9 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.6 1.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.6 3.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.6 6.0 GO:0070836 caveola assembly(GO:0070836)
0.6 1.8 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.6 4.7 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.6 0.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.6 2.9 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.6 5.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.6 4.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6 2.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.6 5.6 GO:0042659 regulation of cell fate specification(GO:0042659)
0.6 2.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 3.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.5 5.5 GO:0042262 DNA protection(GO:0042262)
0.5 1.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.5 12.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.5 1.1 GO:0003162 atrioventricular node development(GO:0003162)
0.5 4.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.5 2.7 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.5 2.6 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.5 2.6 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.5 1.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.5 1.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.5 4.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.5 3.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.5 1.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.5 3.9 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.5 6.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.5 2.4 GO:0030070 insulin processing(GO:0030070)
0.5 4.3 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.5 1.9 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.5 1.4 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.5 2.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.5 1.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 1.9 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.5 4.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.5 1.4 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.4 2.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.4 5.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 2.6 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.4 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.4 1.7 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.4 1.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.4 3.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 2.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 4.6 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.4 0.8 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 1.5 GO:0019046 release from viral latency(GO:0019046)
0.4 1.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.4 2.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.4 8.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.4 1.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.4 2.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 1.8 GO:1903273 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.3 2.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 1.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 6.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 3.6 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.3 8.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 5.2 GO:0043248 proteasome assembly(GO:0043248)
0.3 1.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.3 1.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 6.9 GO:0071294 cellular response to zinc ion(GO:0071294)
0.3 7.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 0.9 GO:0006106 fumarate metabolic process(GO:0006106)
0.3 12.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.3 0.3 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 3.7 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 2.5 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.3 6.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.3 4.9 GO:0000338 protein deneddylation(GO:0000338)
0.3 3.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.3 15.2 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 17.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 1.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 4.4 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.3 0.6 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.3 1.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 2.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.3 7.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.3 1.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 1.1 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 0.8 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 1.1 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 1.5 GO:0035803 egg coat formation(GO:0035803)
0.3 1.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 0.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 2.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 1.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 19.8 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.2 1.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 2.4 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.2 3.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 0.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 1.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2 1.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.2 2.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 3.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 0.7 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2 4.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2 5.9 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.2 1.1 GO:0015692 lead ion transport(GO:0015692)
0.2 1.5 GO:0030091 protein repair(GO:0030091)
0.2 0.6 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 1.5 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.9 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.2 0.6 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 3.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.2 3.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 1.2 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.2 0.6 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) apoptotic process involved in luteolysis(GO:0061364)
0.2 0.8 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 3.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 2.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 1.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.4 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.2 0.6 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) interleukin-5-mediated signaling pathway(GO:0038043)
0.2 1.0 GO:0015722 canalicular bile acid transport(GO:0015722) glycerol transport(GO:0015793) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.2 1.0 GO:2000630 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) positive regulation of miRNA metabolic process(GO:2000630)
0.2 0.8 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 3.7 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.2 1.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 4.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 4.4 GO:0030033 microvillus assembly(GO:0030033)
0.2 2.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 0.8 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 4.7 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2 4.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 1.8 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 3.9 GO:0003094 glomerular filtration(GO:0003094)
0.2 1.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.5 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.2 0.7 GO:0034201 response to oleic acid(GO:0034201)
0.2 1.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 1.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 1.0 GO:0043316 cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
0.2 2.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 11.8 GO:0007632 visual behavior(GO:0007632)
0.2 0.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 5.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.0 GO:0070458 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) cellular detoxification of nitrogen compound(GO:0070458)
0.2 4.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 2.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 1.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 5.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 0.5 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 0.6 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 1.7 GO:1903204 cellular response to hydroperoxide(GO:0071447) negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.2 6.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 3.0 GO:0006465 signal peptide processing(GO:0006465)
0.2 1.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.5 GO:0051451 myoblast migration(GO:0051451)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 1.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 9.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.1 2.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 10.6 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 3.7 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.7 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:1902988 neurofibrillary tangle assembly(GO:1902988)
0.1 0.5 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1 3.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 7.7 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.9 GO:0036010 protein localization to endosome(GO:0036010)
0.1 1.4 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 0.9 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.5 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.4 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 2.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 5.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.0 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 1.1 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1 0.2 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 2.4 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 1.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 2.1 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 0.6 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 4.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.6 GO:0071105 response to interleukin-11(GO:0071105)
0.1 1.2 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.2 GO:0072553 terminal button organization(GO:0072553)
0.1 0.9 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 2.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 5.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.7 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 2.5 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 4.3 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.1 2.9 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 1.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 3.0 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 4.1 GO:0051495 positive regulation of cytoskeleton organization(GO:0051495)
0.1 1.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 2.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 2.2 GO:0008038 neuron recognition(GO:0008038)
0.1 3.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.9 GO:0060004 reflex(GO:0060004)
0.1 5.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.5 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.9 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 1.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.6 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 4.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 0.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.1 1.2 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 1.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.0 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.1 2.5 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1 1.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 2.2 GO:0007566 embryo implantation(GO:0007566)
0.1 0.2 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1 0.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0032971 diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011) regulation of muscle filament sliding(GO:0032971) regulation of muscle filament sliding speed(GO:0032972)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.4 GO:0031648 protein destabilization(GO:0031648)
0.0 2.0 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0 1.6 GO:0043620 regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 2.4 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 1.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 5.4 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.0 GO:0071363 cellular response to growth factor stimulus(GO:0071363)
0.0 1.1 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0034199 activation of protein kinase A activity(GO:0034199) gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.0 2.3 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.9 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.2 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 3.2 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 1.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.8 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 7.9 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.8 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 3.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 1.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 2.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0048003 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.3 GO:0048839 inner ear development(GO:0048839)
0.0 0.1 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.6 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.3 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 2.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 21.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
2.5 12.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.3 6.8 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.7 6.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
1.6 9.8 GO:0071817 MMXD complex(GO:0071817)
1.6 6.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.4 14.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
1.3 3.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
1.2 4.6 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.2 17.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
1.2 9.2 GO:0000322 storage vacuole(GO:0000322)
1.2 10.4 GO:0005955 calcineurin complex(GO:0005955)
1.1 5.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.1 16.9 GO:0036020 endolysosome membrane(GO:0036020)
1.0 9.0 GO:0072546 ER membrane protein complex(GO:0072546)
1.0 14.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.0 5.9 GO:1902560 GMP reductase complex(GO:1902560)
1.0 5.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.9 6.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.7 5.1 GO:0016272 prefoldin complex(GO:0016272)
0.7 7.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.7 2.1 GO:0019034 viral replication complex(GO:0019034)
0.7 4.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.7 3.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.6 4.9 GO:0042382 paraspeckles(GO:0042382)
0.6 9.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.6 7.4 GO:0005869 dynactin complex(GO:0005869)
0.6 17.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.6 6.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.5 1.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5 2.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.5 3.2 GO:1990357 terminal web(GO:1990357)
0.5 2.7 GO:0033503 HULC complex(GO:0033503)
0.5 3.1 GO:0001740 Barr body(GO:0001740)
0.5 2.0 GO:0070695 FHF complex(GO:0070695)
0.5 2.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.5 3.0 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.5 2.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 1.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 16.8 GO:0000421 autophagosome membrane(GO:0000421)
0.4 7.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 4.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.4 3.1 GO:0032584 growth cone membrane(GO:0032584)
0.4 3.0 GO:0005787 signal peptidase complex(GO:0005787)
0.4 8.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 1.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 5.4 GO:0097433 dense body(GO:0097433)
0.4 1.2 GO:0097441 basilar dendrite(GO:0097441)
0.4 2.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.4 1.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.4 2.7 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.4 3.8 GO:0097255 R2TP complex(GO:0097255)
0.4 2.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 7.1 GO:0001891 phagocytic cup(GO:0001891)
0.4 2.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 11.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 5.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 9.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 4.6 GO:0044754 autolysosome(GO:0044754)
0.3 10.9 GO:0032420 stereocilium(GO:0032420)
0.3 4.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 2.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.3 1.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.3 1.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.3 2.7 GO:0044327 dendritic spine head(GO:0044327)
0.3 6.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 1.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.3 2.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 3.1 GO:0016342 catenin complex(GO:0016342)
0.3 15.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 1.5 GO:0008537 proteasome activator complex(GO:0008537)
0.2 2.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 2.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 6.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 1.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 2.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 2.8 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 2.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 2.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 1.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.1 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.9 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.2 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 2.1 GO:0070187 telosome(GO:0070187)
0.2 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 5.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 3.1 GO:0000974 Prp19 complex(GO:0000974)
0.2 2.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 2.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.7 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 2.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 0.9 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 7.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 2.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.2 3.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 3.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 3.6 GO:0031143 pseudopodium(GO:0031143)
0.1 12.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.3 GO:0030897 HOPS complex(GO:0030897)
0.1 1.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 5.8 GO:1904115 axon cytoplasm(GO:1904115)
0.1 4.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 11.0 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 19.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.5 GO:0031968 organelle outer membrane(GO:0031968)
0.1 3.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 6.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 5.4 GO:0030315 T-tubule(GO:0030315)
0.1 2.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 25.3 GO:0030027 lamellipodium(GO:0030027)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 1.0 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 4.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 13.4 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 8.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 7.5 GO:0016020 membrane(GO:0016020)
0.1 1.8 GO:0000145 exocyst(GO:0000145)
0.1 8.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 13.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 5.1 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 12.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 2.3 GO:0005771 multivesicular body(GO:0005771)
0.1 8.7 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.0 GO:0031201 SNARE complex(GO:0031201)
0.1 0.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.1 GO:0034709 methylosome(GO:0034709)
0.1 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 3.2 GO:0008021 synaptic vesicle(GO:0008021)
0.1 6.1 GO:0005903 brush border(GO:0005903)
0.1 6.7 GO:0005923 bicellular tight junction(GO:0005923)
0.1 2.6 GO:0000502 proteasome complex(GO:0000502)
0.1 3.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 4.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 3.9 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 31.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0035631 IkappaB kinase complex(GO:0008385) CD40 receptor complex(GO:0035631)
0.0 5.5 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 4.0 GO:0005770 late endosome(GO:0005770)
0.0 3.3 GO:0031252 cell leading edge(GO:0031252)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 2.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.2 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 7.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.1 GO:0016234 inclusion body(GO:0016234)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 4.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.0 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0043196 varicosity(GO:0043196)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.7 10.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.9 7.6 GO:0004348 glucosylceramidase activity(GO:0004348)
1.7 6.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.7 6.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.6 6.4 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.6 7.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.4 5.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.4 8.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.4 11.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.3 5.3 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
1.2 14.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.1 3.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
1.1 4.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
1.0 10.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
1.0 5.9 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.9 24.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.9 3.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.9 4.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.9 20.1 GO:0046961 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.8 4.2 GO:1990460 leptin receptor binding(GO:1990460)
0.8 5.8 GO:0004849 uridine kinase activity(GO:0004849)
0.8 2.5 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.8 2.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.8 22.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 9.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.7 2.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.7 7.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.7 2.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.7 4.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 3.5 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.7 14.7 GO:0050811 GABA receptor binding(GO:0050811)
0.7 3.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.7 2.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.6 8.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.6 1.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.6 3.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.6 3.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.6 6.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.6 14.3 GO:0031402 sodium ion binding(GO:0031402)
0.6 3.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 7.5 GO:0005167 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.6 2.3 GO:0017040 ceramidase activity(GO:0017040)
0.6 13.8 GO:0045503 dynein light chain binding(GO:0045503)
0.5 9.1 GO:0008432 JUN kinase binding(GO:0008432)
0.5 1.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.5 1.5 GO:0033149 FFAT motif binding(GO:0033149)
0.5 1.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 2.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.5 6.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.5 1.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.5 3.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.9 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.5 13.4 GO:0070410 co-SMAD binding(GO:0070410)
0.5 2.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 1.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.4 2.7 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.4 3.9 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.4 6.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 1.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 5.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 1.7 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.4 2.5 GO:0001849 complement component C1q binding(GO:0001849)
0.4 2.4 GO:1990254 keratin filament binding(GO:1990254)
0.4 1.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.4 1.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.4 3.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 3.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 4.6 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4 5.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.4 2.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.4 2.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.4 2.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.4 6.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 2.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 5.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 2.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.3 1.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 5.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 2.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 3.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 11.5 GO:0070412 R-SMAD binding(GO:0070412)
0.3 2.6 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 11.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 3.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.3 1.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.3 0.9 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.3 2.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 1.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 1.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 8.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 5.9 GO:0001055 RNA polymerase II activity(GO:0001055)
0.3 1.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 8.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 3.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 0.5 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 3.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 4.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 1.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 6.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 14.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 6.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 2.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 6.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.0 GO:0015265 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.2 0.7 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 1.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 2.9 GO:1903136 cuprous ion binding(GO:1903136)
0.2 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 3.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 3.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 18.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 1.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 5.4 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.2 0.6 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 1.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 0.9 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.2 0.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 5.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 1.6 GO:0051425 PTB domain binding(GO:0051425)
0.2 2.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.6 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 0.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 0.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 2.3 GO:0031386 protein tag(GO:0031386)
0.2 0.8 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 0.4 GO:0031013 troponin I binding(GO:0031013)
0.2 4.7 GO:0005521 lamin binding(GO:0005521)
0.2 6.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 2.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 5.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.1 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 1.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 3.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 4.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 1.5 GO:0032190 acrosin binding(GO:0032190)
0.2 1.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 4.6 GO:0030276 clathrin binding(GO:0030276)
0.2 0.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 26.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 7.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 3.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 5.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.6 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 2.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 1.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 6.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 13.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 3.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.4 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 4.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 4.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 2.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.2 GO:0001848 complement binding(GO:0001848)
0.1 5.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 7.1 GO:0005507 copper ion binding(GO:0005507)
0.1 3.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 5.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 2.1 GO:0008242 omega peptidase activity(GO:0008242)
0.1 4.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.9 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.9 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.9 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.1 0.6 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 3.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.1 GO:0089720 caspase binding(GO:0089720)
0.1 1.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 2.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 10.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 22.8 GO:0003924 GTPase activity(GO:0003924)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.0 GO:0043295 glutathione binding(GO:0043295)
0.1 2.0 GO:0071949 FAD binding(GO:0071949)
0.1 1.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.8 GO:0019864 IgG binding(GO:0019864)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 2.2 GO:0019894 kinesin binding(GO:0019894)
0.1 3.6 GO:0000149 SNARE binding(GO:0000149)
0.1 11.0 GO:0051015 actin filament binding(GO:0051015)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 1.3 GO:0000339 RNA cap binding(GO:0000339)
0.1 2.2 GO:0050699 WW domain binding(GO:0050699)
0.1 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.5 GO:0005123 death receptor binding(GO:0005123)
0.1 1.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 2.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 4.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.3 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.9 GO:0008233 peptidase activity(GO:0008233)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 8.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 2.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 6.8 GO:0045296 cadherin binding(GO:0045296)
0.0 5.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 3.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.0 GO:0016791 phosphatase activity(GO:0016791)
0.0 1.4 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.2 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 3.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 23.2 PID ARF 3PATHWAY Arf1 pathway
0.7 23.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6 25.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.4 4.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 4.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.3 9.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 1.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.3 8.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 10.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 9.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.3 9.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 24.1 PID CDC42 PATHWAY CDC42 signaling events
0.2 19.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 6.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 3.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 6.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 8.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 4.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 7.8 PID MYC PATHWAY C-MYC pathway
0.2 8.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 18.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 1.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 9.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 5.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 4.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 4.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 6.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 6.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.4 PID ATR PATHWAY ATR signaling pathway
0.1 8.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 4.9 PID P53 REGULATION PATHWAY p53 pathway
0.1 4.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.3 PID E2F PATHWAY E2F transcription factor network
0.1 2.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 26.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.9 16.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.8 14.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.8 21.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.6 1.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.6 19.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.5 12.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.5 9.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.5 16.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 8.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5 5.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 41.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.4 12.8 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.4 12.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.4 6.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 4.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.4 3.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 22.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 13.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 3.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3 6.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 4.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 10.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.3 3.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 12.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 9.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 3.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 10.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 1.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 6.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 3.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 8.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 2.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 2.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 0.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2 3.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 4.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 8.9 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.2 2.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 10.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 2.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 2.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 3.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 3.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 5.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 7.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 3.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 6.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 3.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 15.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 11.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 6.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 3.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 4.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 4.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 6.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.6 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 3.4 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 1.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 3.0 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 1.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1 3.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 2.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 6.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 0.5 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.1 2.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.0 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 1.3 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle