Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for MNT_HEY1_HEY2
Z-value: 2.03
Motif logo
Transcription factors associated with MNT_HEY1_HEY2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MNT
|
ENSG00000070444.10 | MAX network transcriptional repressor |
|
HEY1
|
ENSG00000164683.12 | hes related family bHLH transcription factor with YRPW motif 1 |
|
HEY2
|
ENSG00000135547.4 | hes related family bHLH transcription factor with YRPW motif 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HEY2 | hg19_v2_chr6_+_126070726_126070768 | 0.65 | 4.6e-28 | Click! |
| HEY1 | hg19_v2_chr8_-_80680078_80680101 | 0.29 | 1.1e-05 | Click! |
| MNT | hg19_v2_chr17_-_2304365_2304412 | -0.26 | 9.9e-05 | Click! |
Activity profile of MNT_HEY1_HEY2 motif
Sorted Z-values of MNT_HEY1_HEY2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MNT_HEY1_HEY2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 26.5 | 132.6 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 24.1 | 48.2 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 17.5 | 69.9 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 15.5 | 124.2 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 13.9 | 138.5 | GO:0051610 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 13.3 | 39.9 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 11.7 | 11.7 | GO:0045347 | MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 10.2 | 30.7 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 10.1 | 30.2 | GO:0022007 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 9.7 | 29.0 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 9.2 | 27.6 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 8.6 | 25.7 | GO:1904530 | negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617) |
| 8.3 | 25.0 | GO:0051039 | histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 8.3 | 16.5 | GO:1902263 | apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 8.0 | 8.0 | GO:1900369 | regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) |
| 8.0 | 63.7 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 7.9 | 23.8 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 7.4 | 14.7 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 7.3 | 14.7 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
| 7.3 | 36.4 | GO:0032383 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 7.2 | 28.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 7.2 | 28.6 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 7.0 | 28.0 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
| 6.7 | 6.7 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 6.4 | 19.2 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 6.1 | 18.3 | GO:1903401 | lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transmembrane transport(GO:1903401) L-lysine import into cell(GO:1903410) |
| 6.1 | 18.2 | GO:1902960 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 5.8 | 29.0 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 5.6 | 101.3 | GO:0050812 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 5.6 | 16.8 | GO:0021722 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 5.6 | 22.4 | GO:1904048 | regulation of spontaneous neurotransmitter secretion(GO:1904048) |
| 5.6 | 16.7 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 5.5 | 22.0 | GO:1904379 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 5.5 | 16.4 | GO:0000294 | nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) |
| 5.3 | 144.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 5.3 | 10.6 | GO:0060168 | positive regulation of adenosine receptor signaling pathway(GO:0060168) |
| 5.2 | 15.6 | GO:0036079 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 5.2 | 15.6 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 5.2 | 5.2 | GO:0052803 | histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803) |
| 5.1 | 25.7 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 5.1 | 15.3 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 5.1 | 25.3 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 5.0 | 15.0 | GO:1990523 | negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523) |
| 5.0 | 20.0 | GO:1902075 | cellular response to salt(GO:1902075) |
| 4.9 | 19.6 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 4.9 | 19.4 | GO:1901162 | primary amino compound biosynthetic process(GO:1901162) |
| 4.8 | 24.2 | GO:1903564 | regulation of protein localization to cilium(GO:1903564) |
| 4.6 | 9.3 | GO:0003250 | cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) |
| 4.6 | 13.9 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 4.5 | 75.9 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 4.3 | 30.2 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 4.3 | 25.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 4.2 | 16.9 | GO:0033123 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 4.2 | 25.2 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
| 4.2 | 29.3 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 4.1 | 24.7 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 4.1 | 4.1 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 4.0 | 19.9 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 3.8 | 23.0 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 3.8 | 11.5 | GO:0045643 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 3.8 | 3.8 | GO:0035106 | operant conditioning(GO:0035106) |
| 3.8 | 11.3 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 3.8 | 7.5 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 3.7 | 22.3 | GO:0052551 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 3.7 | 11.1 | GO:0003285 | septum secundum development(GO:0003285) |
| 3.6 | 18.1 | GO:0003431 | growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384) |
| 3.6 | 39.3 | GO:0015886 | heme transport(GO:0015886) |
| 3.5 | 10.6 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
| 3.5 | 10.6 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
| 3.5 | 3.5 | GO:0051885 | positive regulation of anagen(GO:0051885) |
| 3.5 | 24.5 | GO:0019532 | oxalate transport(GO:0019532) |
| 3.5 | 27.7 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 3.4 | 10.3 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 3.4 | 13.7 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 3.4 | 17.0 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 3.4 | 10.1 | GO:0003175 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) negative regulation of transcription by transcription factor localization(GO:0010621) |
| 3.2 | 9.6 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 3.2 | 3.2 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 3.2 | 9.5 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 3.1 | 9.4 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 3.1 | 15.3 | GO:0090650 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 3.0 | 9.1 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 3.0 | 11.9 | GO:0010157 | response to chlorate(GO:0010157) |
| 2.9 | 20.3 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 2.9 | 5.8 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 2.9 | 5.7 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 2.8 | 30.8 | GO:0035751 | regulation of lysosomal lumen pH(GO:0035751) |
| 2.7 | 19.1 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 2.7 | 40.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 2.7 | 8.1 | GO:0036090 | cleavage furrow ingression(GO:0036090) |
| 2.7 | 24.1 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 2.7 | 8.0 | GO:0060437 | lung growth(GO:0060437) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) |
| 2.6 | 10.4 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 2.5 | 4.9 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 2.5 | 32.0 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 2.4 | 22.0 | GO:2000047 | regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 2.4 | 14.3 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 2.4 | 19.0 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 2.4 | 7.1 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 2.4 | 4.7 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 2.3 | 7.0 | GO:0035606 | induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) |
| 2.3 | 6.9 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 2.3 | 20.5 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 2.2 | 31.0 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 2.2 | 4.3 | GO:0007412 | axon target recognition(GO:0007412) |
| 2.1 | 6.4 | GO:1903697 | negative regulation of microvillus assembly(GO:1903697) |
| 2.1 | 21.4 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 2.1 | 8.6 | GO:0009386 | translational attenuation(GO:0009386) |
| 2.1 | 8.5 | GO:0006498 | N-terminal protein lipidation(GO:0006498) |
| 2.1 | 23.0 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 2.1 | 29.0 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 2.1 | 4.1 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 2.1 | 10.3 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 2.0 | 8.0 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 2.0 | 7.9 | GO:0043321 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 2.0 | 5.9 | GO:1900075 | regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) |
| 1.9 | 13.5 | GO:0050893 | sensory processing(GO:0050893) |
| 1.9 | 9.6 | GO:0086053 | SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
| 1.9 | 3.8 | GO:0051026 | chiasma assembly(GO:0051026) |
| 1.9 | 5.6 | GO:0097359 | UDP-glucosylation(GO:0097359) |
| 1.9 | 5.6 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 1.8 | 3.6 | GO:0045646 | regulation of erythrocyte differentiation(GO:0045646) |
| 1.8 | 32.2 | GO:0007141 | male meiosis I(GO:0007141) |
| 1.8 | 26.7 | GO:0014029 | neural crest formation(GO:0014029) |
| 1.8 | 5.3 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
| 1.8 | 23.0 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
| 1.8 | 7.0 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 1.7 | 29.5 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 1.7 | 10.4 | GO:0010734 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 1.7 | 6.9 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
| 1.7 | 6.8 | GO:0021784 | postganglionic parasympathetic fiber development(GO:0021784) |
| 1.7 | 5.1 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 1.7 | 5.1 | GO:0009183 | ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) |
| 1.7 | 10.1 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 1.7 | 5.0 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 1.7 | 8.4 | GO:0071543 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 1.7 | 10.0 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 1.6 | 11.5 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 1.6 | 4.9 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 1.6 | 16.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 1.6 | 8.2 | GO:0030885 | regulation of myeloid dendritic cell activation(GO:0030885) |
| 1.6 | 11.4 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 1.6 | 26.2 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 1.6 | 8.0 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 1.6 | 6.3 | GO:0015808 | L-alanine transport(GO:0015808) |
| 1.6 | 4.7 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 1.6 | 25.3 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 1.6 | 9.4 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 1.6 | 4.7 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 1.5 | 15.3 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 1.5 | 6.1 | GO:2000980 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 1.5 | 6.1 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 1.5 | 4.5 | GO:1901859 | negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) |
| 1.5 | 10.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 1.5 | 10.5 | GO:0002414 | immunoglobulin transcytosis in epithelial cells(GO:0002414) |
| 1.5 | 20.8 | GO:0035878 | nail development(GO:0035878) |
| 1.5 | 1.5 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 1.5 | 11.7 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 1.4 | 8.7 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 1.4 | 47.7 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 1.4 | 2.9 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 1.4 | 5.7 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 1.4 | 7.1 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 1.4 | 9.8 | GO:0045007 | depurination(GO:0045007) |
| 1.4 | 5.6 | GO:2001137 | positive regulation of endocytic recycling(GO:2001137) |
| 1.4 | 37.3 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 1.4 | 20.7 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 1.3 | 4.0 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 1.3 | 5.3 | GO:1904354 | negative regulation of telomere capping(GO:1904354) |
| 1.3 | 6.6 | GO:0009233 | menaquinone metabolic process(GO:0009233) |
| 1.3 | 3.9 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
| 1.3 | 7.7 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 1.3 | 5.1 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 1.3 | 5.1 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 1.3 | 1.3 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 1.3 | 6.4 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 1.3 | 8.8 | GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 1.3 | 15.1 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 1.2 | 2.5 | GO:1901895 | negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 1.2 | 3.7 | GO:0061055 | myotome development(GO:0061055) |
| 1.2 | 18.3 | GO:1903358 | regulation of Golgi organization(GO:1903358) |
| 1.2 | 7.3 | GO:0002865 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of synaptic transmission, GABAergic(GO:0032229) |
| 1.2 | 12.1 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 1.2 | 9.6 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 1.2 | 9.6 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 1.2 | 3.6 | GO:0007497 | posterior midgut development(GO:0007497) |
| 1.2 | 2.4 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
| 1.2 | 21.4 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 1.2 | 9.5 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 1.2 | 8.2 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 1.2 | 8.2 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 1.2 | 13.9 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 1.2 | 1.2 | GO:1902961 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 1.1 | 13.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 1.1 | 13.7 | GO:0006108 | malate metabolic process(GO:0006108) |
| 1.1 | 13.7 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 1.1 | 6.8 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 1.1 | 10.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 1.1 | 4.5 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 1.1 | 11.2 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 1.1 | 16.8 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 1.1 | 25.8 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 1.1 | 2.2 | GO:0006907 | pinocytosis(GO:0006907) |
| 1.1 | 13.4 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 1.1 | 6.6 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 1.1 | 3.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 1.1 | 10.8 | GO:0015781 | pyrimidine nucleotide-sugar transport(GO:0015781) |
| 1.1 | 7.5 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 1.1 | 3.2 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 1.1 | 2.1 | GO:2000824 | negative regulation of androgen receptor activity(GO:2000824) |
| 1.1 | 3.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 1.1 | 12.7 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
| 1.0 | 5.2 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 1.0 | 9.3 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 1.0 | 8.2 | GO:0006531 | aspartate metabolic process(GO:0006531) |
| 1.0 | 4.1 | GO:0007163 | establishment or maintenance of cell polarity(GO:0007163) |
| 1.0 | 19.0 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 1.0 | 3.0 | GO:1901993 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 1.0 | 3.0 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
| 1.0 | 2.0 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 1.0 | 4.9 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 1.0 | 4.9 | GO:0045915 | positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964) |
| 1.0 | 2.9 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 1.0 | 6.7 | GO:2000773 | negative regulation of cellular senescence(GO:2000773) |
| 1.0 | 1.9 | GO:0060748 | tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) |
| 0.9 | 0.9 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) |
| 0.9 | 67.7 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.9 | 8.4 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.9 | 9.4 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
| 0.9 | 8.4 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.9 | 40.6 | GO:0035036 | sperm-egg recognition(GO:0035036) |
| 0.9 | 21.1 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.9 | 2.7 | GO:1990535 | neuron projection maintenance(GO:1990535) |
| 0.9 | 6.2 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.9 | 8.8 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.9 | 1.7 | GO:0070827 | chromatin maintenance(GO:0070827) |
| 0.8 | 4.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.8 | 3.4 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.8 | 7.5 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.8 | 6.7 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.8 | 1.7 | GO:0032966 | negative regulation of collagen biosynthetic process(GO:0032966) |
| 0.8 | 7.4 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.8 | 9.8 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.8 | 3.2 | GO:0042182 | ketone catabolic process(GO:0042182) |
| 0.8 | 2.4 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
| 0.8 | 8.7 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.8 | 6.4 | GO:0006836 | neurotransmitter transport(GO:0006836) |
| 0.8 | 14.2 | GO:0010002 | cardioblast differentiation(GO:0010002) |
| 0.8 | 29.0 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.8 | 6.3 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.8 | 12.5 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
| 0.8 | 14.8 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.8 | 2.3 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
| 0.8 | 3.1 | GO:2001270 | regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.8 | 1.5 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 0.8 | 3.8 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.8 | 18.9 | GO:0007628 | adult walking behavior(GO:0007628) |
| 0.8 | 16.5 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.7 | 45.7 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
| 0.7 | 8.2 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.7 | 2.2 | GO:0097056 | seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056) |
| 0.7 | 4.5 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.7 | 5.2 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.7 | 3.0 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.7 | 20.7 | GO:0040019 | positive regulation of embryonic development(GO:0040019) |
| 0.7 | 0.7 | GO:0060157 | urinary bladder development(GO:0060157) |
| 0.7 | 3.7 | GO:0051122 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
| 0.7 | 2.2 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.7 | 2.9 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.7 | 2.2 | GO:0060174 | limb bud formation(GO:0060174) |
| 0.7 | 15.0 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.7 | 10.7 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 0.7 | 8.6 | GO:0030238 | male sex determination(GO:0030238) |
| 0.7 | 2.8 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.7 | 2.1 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.7 | 2.1 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.7 | 0.7 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.7 | 26.9 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.7 | 2.7 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 0.7 | 68.0 | GO:0007286 | spermatid development(GO:0007286) |
| 0.7 | 8.0 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.7 | 2.0 | GO:0035936 | testosterone secretion(GO:0035936) regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845) |
| 0.6 | 1.9 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.6 | 5.1 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.6 | 14.1 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.6 | 9.0 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.6 | 4.5 |