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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MNT_HEY1_HEY2

Z-value: 2.03

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Transcription factors associated with MNT_HEY1_HEY2

Gene Symbol Gene ID Gene Info
MNT
ENSG00000070444.10 MAX network transcriptional repressor
HEY1
ENSG00000164683.12 hes related family bHLH transcription factor with YRPW motif 1
HEY2
ENSG00000135547.4 hes related family bHLH transcription factor with YRPW motif 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HEY2hg19_v2_chr6_+_126070726_1260707680.654.6e-28Click!
HEY1hg19_v2_chr8_-_80680078_806801010.291.1e-05Click!
MNThg19_v2_chr17_-_2304365_2304412-0.269.9e-05Click!

Activity profile of MNT_HEY1_HEY2 motif

Sorted Z-values of MNT_HEY1_HEY2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_154193009 91.05 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43
chromosome 1 open reading frame 43
chr1_+_11866270 82.57 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr1_-_11866034 73.15 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_13956497 63.91 ENST00000398361.3
GPM6B
glycoprotein M6B
chr1_+_11866207 61.48 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr22_+_40390930 61.00 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr1_-_11865982 59.46 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr2_-_38604398 59.32 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
ATL2
atlastin GTPase 2
chr4_+_76439665 58.46 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6
THAP domain containing 6
chr16_+_66914264 56.41 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chrX_-_13956737 56.17 ENST00000454189.2
GPM6B
glycoprotein M6B
chr1_-_241520525 55.95 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr4_+_128651530 53.61 ENST00000281154.4
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr19_-_5340730 48.17 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr9_+_74526384 46.69 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr5_-_131132614 46.23 ENST00000307968.7
ENST00000307954.8
FNIP1
folliculin interacting protein 1
chr12_+_130554803 44.36 ENST00000535487.1
RP11-474D1.2
RP11-474D1.2
chr1_-_241520385 40.97 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr15_+_75118888 40.84 ENST00000395018.4
CPLX3
complexin 3
chr16_+_6533380 40.60 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_203499901 40.53 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr22_-_36903101 40.25 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr19_-_10764509 40.16 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr22_-_36903069 39.35 ENST00000216187.6
ENST00000423980.1
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr7_+_72742178 37.11 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr12_-_122751002 35.93 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr14_-_81687197 35.19 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr1_-_52831796 35.00 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
CC2D1B
coiled-coil and C2 domain containing 1B
chr7_+_72742162 33.01 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr11_-_66336060 32.71 ENST00000310325.5
CTSF
cathepsin F
chr14_-_81687575 32.61 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr6_+_31865552 31.98 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr15_-_83316254 31.76 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr11_+_125774362 31.28 ENST00000530414.1
ENST00000530129.2
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr5_+_55033845 31.09 ENST00000353507.5
ENST00000514278.2
ENST00000505374.1
ENST00000506511.1
DDX4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr1_+_154193325 30.96 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr11_-_116968987 30.61 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chrX_+_153524024 30.23 ENST00000369915.3
ENST00000217905.7
TKTL1
transketolase-like 1
chrX_+_38420783 29.72 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr11_+_125774258 29.48 ENST00000263576.6
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr11_+_65479702 29.21 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5
K(lysine) acetyltransferase 5
chr19_+_2977444 29.04 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr1_+_233086326 29.02 ENST00000366628.5
ENST00000366627.4
NTPCR
nucleoside-triphosphatase, cancer-related
chr11_-_66725837 29.00 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chr20_+_44657845 28.64 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr17_-_6915646 28.35 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr8_-_67341208 27.92 ENST00000499642.1
RP11-346I3.4
RP11-346I3.4
chr22_+_41777927 27.76 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr8_+_95908041 27.69 ENST00000396113.1
ENST00000519136.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr22_+_24891210 27.65 ENST00000382760.2
UPB1
ureidopropionase, beta
chr5_-_133706695 27.62 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr9_+_139871948 27.32 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr12_+_58013693 26.87 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10
chr2_-_68384603 26.35 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92
WD repeat domain 92
chr17_+_17942684 25.76 ENST00000376345.3
GID4
GID complex subunit 4
chr4_-_5891918 25.74 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr12_+_50355647 25.28 ENST00000293599.6
AQP5
aquaporin 5
chr16_+_4897632 25.11 ENST00000262376.6
UBN1
ubinuclein 1
chr10_+_104474207 25.11 ENST00000602831.1
ENST00000369893.5
SFXN2
sideroflexin 2
chr11_-_777467 24.92 ENST00000397472.2
ENST00000524550.1
ENST00000319863.8
ENST00000526325.1
ENST00000442059.2
PDDC1
Parkinson disease 7 domain containing 1
chr19_+_5681011 24.72 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr16_-_4588469 24.62 ENST00000588381.1
ENST00000563332.2
CDIP1
cell death-inducing p53 target 1
chr2_+_17721920 24.60 ENST00000295156.4
VSNL1
visinin-like 1
chr11_-_61684962 24.57 ENST00000394836.2
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr17_-_2614927 24.14 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr1_+_9599540 23.76 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr19_+_41903709 23.40 ENST00000542943.1
ENST00000457836.2
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr19_-_49137790 23.37 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr17_-_41465674 23.12 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910
long intergenic non-protein coding RNA 910
chr11_-_64511789 23.09 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_47164386 23.03 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr19_-_46974741 22.90 ENST00000313683.10
ENST00000602246.1
PNMAL1
paraneoplastic Ma antigen family-like 1
chr10_-_120514720 22.60 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr16_-_4897266 22.57 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr17_+_17942594 22.54 ENST00000268719.4
GID4
GID complex subunit 4
chr2_+_173420697 22.41 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr19_-_46974664 22.33 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr17_-_7137582 22.10 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr7_+_97361218 22.01 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr3_-_57678772 21.99 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr14_-_92572894 21.96 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr3_-_45883558 21.31 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr11_+_9595180 21.30 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr1_-_113498616 21.28 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr9_-_139922726 20.83 ENST00000265662.5
ENST00000371605.3
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr20_+_42839600 20.72 ENST00000439943.1
ENST00000437730.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr18_+_23806437 20.52 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr16_+_84178874 20.22 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr12_+_54332535 19.92 ENST00000243056.3
HOXC13
homeobox C13
chr19_-_49137762 19.86 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr18_-_21977748 19.79 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr2_-_220042825 19.78 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr20_+_42839722 19.64 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr9_+_6757634 19.47 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr1_-_15911510 19.45 ENST00000375826.3
AGMAT
agmatine ureohydrolase (agmatinase)
chr17_+_76311791 19.40 ENST00000586321.1
AC061992.2
AC061992.2
chr19_-_12833361 19.13 ENST00000592287.1
TNPO2
transportin 2
chr8_+_142402089 18.98 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr7_+_148959262 18.88 ENST00000434415.1
ZNF783
zinc finger family member 783
chr18_+_9136758 18.64 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr2_-_50574856 18.58 ENST00000342183.5
NRXN1
neurexin 1
chr11_-_9781068 18.39 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr5_+_149737202 18.39 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr12_-_114404111 18.27 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RBM19
RNA binding motif protein 19
chr11_+_121322832 18.18 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr7_-_50132801 18.18 ENST00000419417.1
ZPBP
zona pellucida binding protein
chr11_-_125366089 17.97 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr7_-_50132860 17.93 ENST00000046087.2
ZPBP
zona pellucida binding protein
chr7_+_97361388 17.84 ENST00000350485.4
ENST00000346867.4
TAC1
tachykinin, precursor 1
chr1_-_151319283 17.79 ENST00000392746.3
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chrX_+_102469997 17.41 ENST00000372695.5
ENST00000372691.3
BEX4
brain expressed, X-linked 4
chr16_+_11762270 17.40 ENST00000329565.5
SNN
stannin
chr2_+_10183651 17.27 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr5_-_131132658 17.21 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr3_+_147127142 17.10 ENST00000282928.4
ZIC1
Zic family member 1
chr7_-_103629963 17.06 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr2_-_220083671 17.05 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr9_+_130159504 17.03 ENST00000373352.1
ENST00000373360.3
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr5_-_172198190 17.03 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr15_-_83316711 16.83 ENST00000568128.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr9_+_131709966 16.81 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr17_+_30813576 16.80 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr2_-_220083692 16.73 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr7_+_2559399 16.68 ENST00000222725.5
ENST00000359574.3
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_111878483 16.50 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr12_-_54020107 16.40 ENST00000588232.1
ENST00000548446.2
ENST00000420353.2
ENST00000591397.1
ENST00000415113.1
ATF7
activating transcription factor 7
chr18_+_56530794 16.28 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr3_+_33318914 16.27 ENST00000484457.1
ENST00000538892.1
ENST00000538181.1
ENST00000446237.3
ENST00000507198.1
FBXL2
F-box and leucine-rich repeat protein 2
chr18_-_13726510 16.27 ENST00000322247.3
ENST00000592976.1
ENST00000402563.1
ENST00000591269.1
FAM210A
family with sequence similarity 210, member A
chrX_-_102319092 16.26 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr6_-_99873145 16.21 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr6_-_35109080 16.21 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
TCP11
t-complex 11, testis-specific
chr9_+_17135016 16.21 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr16_-_70719925 16.21 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr8_-_110656995 16.06 ENST00000276646.9
ENST00000533065.1
SYBU
syntabulin (syntaxin-interacting)
chr9_-_100684845 15.68 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr18_-_21017817 15.63 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
TMEM241
transmembrane protein 241
chr20_+_30946106 15.62 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr12_-_45270151 15.57 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr9_-_139922631 15.54 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr14_+_96505659 15.51 ENST00000555004.1
C14orf132
chromosome 14 open reading frame 132
chr12_+_117176090 15.45 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
RNFT2
ring finger protein, transmembrane 2
chr12_-_45270077 15.44 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr9_-_135819987 15.42 ENST00000298552.3
ENST00000403810.1
TSC1
tuberous sclerosis 1
chr17_+_73975292 15.36 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chr13_+_42031679 15.34 ENST00000379359.3
RGCC
regulator of cell cycle
chr6_-_39197226 15.32 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr13_+_103451399 15.30 ENST00000257336.1
ENST00000448849.2
BIVM
basic, immunoglobulin-like variable motif containing
chr3_+_50712672 15.29 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr9_+_130159409 15.18 ENST00000373371.3
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr7_-_44365020 15.17 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr15_-_83316087 15.08 ENST00000568757.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr4_+_176986978 15.07 ENST00000508596.1
ENST00000393643.2
WDR17
WD repeat domain 17
chr2_+_17721230 15.05 ENST00000457525.1
VSNL1
visinin-like 1
chr7_+_72848092 14.98 ENST00000344575.3
FZD9
frizzled family receptor 9
chr17_-_74722672 14.94 ENST00000397625.4
ENST00000445478.2
JMJD6
jumonji domain containing 6
chr1_+_92414928 14.89 ENST00000362005.3
ENST00000370389.2
ENST00000399546.2
ENST00000423434.1
ENST00000394530.3
ENST00000440509.1
BRDT
bromodomain, testis-specific
chrX_-_48433275 14.88 ENST00000376775.2
AC115618.1
Uncharacterized protein; cDNA FLJ26048 fis, clone PRS02384
chr11_+_7534999 14.82 ENST00000528947.1
ENST00000299492.4
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_150229554 14.80 ENST00000369111.4
CA14
carbonic anhydrase XIV
chrX_-_107979616 14.78 ENST00000372129.2
IRS4
insulin receptor substrate 4
chr10_-_75634219 14.74 ENST00000305762.7
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr6_-_151773232 14.74 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr6_+_127587755 14.66 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr19_-_48018203 14.65 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr6_-_84937314 14.64 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr7_+_43152191 14.60 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr3_-_42306248 14.57 ENST00000334681.5
CCK
cholecystokinin
chr10_-_44070016 14.56 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
ZNF239
zinc finger protein 239
chrX_+_11776410 14.55 ENST00000361672.2
MSL3
male-specific lethal 3 homolog (Drosophila)
chr19_-_12833164 14.54 ENST00000356861.5
TNPO2
transportin 2
chr21_+_35747773 14.51 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
SMIM11
small integral membrane protein 11
chr17_+_48172639 14.51 ENST00000503176.1
ENST00000503614.1
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr7_-_44365216 14.50 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr6_-_35109145 14.44 ENST00000373974.4
ENST00000244645.3
TCP11
t-complex 11, testis-specific
chr19_-_45909585 14.42 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr14_-_93799360 14.41 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTBD7
BTB (POZ) domain containing 7
chr10_-_11653753 14.34 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr22_-_38577782 14.19 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr17_-_34890709 14.14 ENST00000544606.1
MYO19
myosin XIX
chr12_+_54674482 14.06 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1
chr2_-_220108309 14.01 ENST00000409640.1
GLB1L
galactosidase, beta 1-like
chr11_+_67159416 13.92 ENST00000307980.2
ENST00000544620.1
RAD9A
RAD9 homolog A (S. pombe)
chr10_+_49514698 13.87 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr17_-_37309480 13.86 ENST00000539608.1
PLXDC1
plexin domain containing 1
chr19_-_18632861 13.83 ENST00000262809.4
ELL
elongation factor RNA polymerase II
chrX_-_153523462 13.82 ENST00000361930.3
ENST00000369926.1
TEX28
testis expressed 28
chr15_-_64126084 13.79 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HERC1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr9_-_131709858 13.79 ENST00000372586.3
DOLK
dolichol kinase
chr22_-_38577731 13.77 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr12_-_123849374 13.76 ENST00000602398.1
ENST00000602750.1
SBNO1
strawberry notch homolog 1 (Drosophila)
chr13_-_36788718 13.75 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr10_-_6019455 13.60 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr22_+_18593446 13.60 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr13_+_35516390 13.53 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr7_-_22396533 13.51 ENST00000344041.6
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chrX_+_54556633 13.42 ENST00000336470.4
ENST00000360845.2
GNL3L
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr3_+_10857885 13.36 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr21_+_34697258 13.34 ENST00000442071.1
ENST00000442357.2
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr10_-_99447024 13.33 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MNT_HEY1_HEY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
26.5 132.6 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
24.1 48.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
17.5 69.9 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
15.5 124.2 GO:0034587 piRNA metabolic process(GO:0034587)
13.9 138.5 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
13.3 39.9 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
11.7 11.7 GO:0045347 MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
10.2 30.7 GO:1902490 regulation of sperm capacitation(GO:1902490)
10.1 30.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
9.7 29.0 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
9.2 27.6 GO:0019482 beta-alanine metabolic process(GO:0019482)
8.6 25.7 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
8.3 25.0 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
8.3 16.5 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
8.0 8.0 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
8.0 63.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
7.9 23.8 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
7.4 14.7 GO:0070129 regulation of mitochondrial translation(GO:0070129)
7.3 14.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
7.3 36.4 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
7.2 28.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
7.2 28.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
7.0 28.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
6.7 6.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
6.4 19.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
6.1 18.3 GO:1903401 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transmembrane transport(GO:1903401) L-lysine import into cell(GO:1903410)
6.1 18.2 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
5.8 29.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
5.6 101.3 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
5.6 16.8 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
5.6 22.4 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
5.6 16.7 GO:0014807 regulation of somitogenesis(GO:0014807)
5.5 22.0 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
5.5 16.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
5.3 144.4 GO:0006884 cell volume homeostasis(GO:0006884)
5.3 10.6 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
5.2 15.6 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
5.2 15.6 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
5.2 5.2 GO:0052803 histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
5.1 25.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
5.1 15.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
5.1 25.3 GO:0015670 carbon dioxide transport(GO:0015670)
5.0 15.0 GO:1990523 negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523)
5.0 20.0 GO:1902075 cellular response to salt(GO:1902075)
4.9 19.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
4.9 19.4 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
4.8 24.2 GO:1903564 regulation of protein localization to cilium(GO:1903564)
4.6 9.3 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
4.6 13.9 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
4.5 75.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
4.3 30.2 GO:0006772 thiamine metabolic process(GO:0006772)
4.3 25.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
4.2 16.9 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
4.2 25.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
4.2 29.3 GO:0071494 cellular response to UV-C(GO:0071494)
4.1 24.7 GO:1990504 dense core granule exocytosis(GO:1990504)
4.1 4.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
4.0 19.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
3.8 23.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
3.8 11.5 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
3.8 3.8 GO:0035106 operant conditioning(GO:0035106)
3.8 11.3 GO:0019858 cytosine metabolic process(GO:0019858)
3.8 7.5 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
3.7 22.3 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
3.7 11.1 GO:0003285 septum secundum development(GO:0003285)
3.6 18.1 GO:0003431 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384)
3.6 39.3 GO:0015886 heme transport(GO:0015886)
3.5 10.6 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
3.5 10.6 GO:0003358 noradrenergic neuron development(GO:0003358)
3.5 3.5 GO:0051885 positive regulation of anagen(GO:0051885)
3.5 24.5 GO:0019532 oxalate transport(GO:0019532)
3.5 27.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
3.4 10.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
3.4 13.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
3.4 17.0 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
3.4 10.1 GO:0003175 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) negative regulation of transcription by transcription factor localization(GO:0010621)
3.2 9.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
3.2 3.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
3.2 9.5 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
3.1 9.4 GO:0045773 positive regulation of axon extension(GO:0045773)
3.1 15.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
3.0 9.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
3.0 11.9 GO:0010157 response to chlorate(GO:0010157)
2.9 20.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
2.9 5.8 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
2.9 5.7 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
2.8 30.8 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
2.7 19.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
2.7 40.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
2.7 8.1 GO:0036090 cleavage furrow ingression(GO:0036090)
2.7 24.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
2.7 8.0 GO:0060437 lung growth(GO:0060437) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.6 10.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
2.5 4.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
2.5 32.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
2.4 22.0 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
2.4 14.3 GO:0098535 de novo centriole assembly(GO:0098535)
2.4 19.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
2.4 7.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
2.4 4.7 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
2.3 7.0 GO:0035606 induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
2.3 6.9 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
2.3 20.5 GO:0036158 outer dynein arm assembly(GO:0036158)
2.2 31.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
2.2 4.3 GO:0007412 axon target recognition(GO:0007412)
2.1 6.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
2.1 21.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
2.1 8.6 GO:0009386 translational attenuation(GO:0009386)
2.1 8.5 GO:0006498 N-terminal protein lipidation(GO:0006498)
2.1 23.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
2.1 29.0 GO:0007130 synaptonemal complex assembly(GO:0007130)
2.1 4.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
2.1 10.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
2.0 8.0 GO:0000255 allantoin metabolic process(GO:0000255)
2.0 7.9 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
2.0 5.9 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.9 13.5 GO:0050893 sensory processing(GO:0050893)
1.9 9.6 GO:0086053 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.9 3.8 GO:0051026 chiasma assembly(GO:0051026)
1.9 5.6 GO:0097359 UDP-glucosylation(GO:0097359)
1.9 5.6 GO:0032053 ciliary basal body organization(GO:0032053)
1.8 3.6 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
1.8 32.2 GO:0007141 male meiosis I(GO:0007141)
1.8 26.7 GO:0014029 neural crest formation(GO:0014029)
1.8 5.3 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
1.8 23.0 GO:0045351 type I interferon biosynthetic process(GO:0045351)
1.8 7.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.7 29.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
1.7 10.4 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.7 6.9 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.7 6.8 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
1.7 5.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.7 5.1 GO:0009183 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
1.7 10.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.7 5.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.7 8.4 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.7 10.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.6 11.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.6 4.9 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.6 16.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.6 8.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
1.6 11.4 GO:0048318 axial mesoderm development(GO:0048318)
1.6 26.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.6 8.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.6 6.3 GO:0015808 L-alanine transport(GO:0015808)
1.6 4.7 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.6 25.3 GO:0045475 locomotor rhythm(GO:0045475)
1.6 9.4 GO:0018095 protein polyglutamylation(GO:0018095)
1.6 4.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
1.5 15.3 GO:0030322 stabilization of membrane potential(GO:0030322)
1.5 6.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.5 6.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.5 4.5 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.5 10.5 GO:0007256 activation of JNKK activity(GO:0007256)
1.5 10.5 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.5 20.8 GO:0035878 nail development(GO:0035878)
1.5 1.5 GO:0006543 glutamine catabolic process(GO:0006543)
1.5 11.7 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.4 8.7 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
1.4 47.7 GO:0090140 regulation of mitochondrial fission(GO:0090140)
1.4 2.9 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.4 5.7 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
1.4 7.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
1.4 9.8 GO:0045007 depurination(GO:0045007)
1.4 5.6 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
1.4 37.3 GO:0000729 DNA double-strand break processing(GO:0000729)
1.4 20.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
1.3 4.0 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.3 5.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
1.3 6.6 GO:0009233 menaquinone metabolic process(GO:0009233)
1.3 3.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
1.3 7.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.3 5.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.3 5.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.3 1.3 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
1.3 6.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.3 8.8 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.3 15.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
1.2 2.5 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.2 3.7 GO:0061055 myotome development(GO:0061055)
1.2 18.3 GO:1903358 regulation of Golgi organization(GO:1903358)
1.2 7.3 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of synaptic transmission, GABAergic(GO:0032229)
1.2 12.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
1.2 9.6 GO:1901525 negative regulation of macromitophagy(GO:1901525)
1.2 9.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.2 3.6 GO:0007497 posterior midgut development(GO:0007497)
1.2 2.4 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.2 21.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.2 9.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.2 8.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.2 8.2 GO:0055089 fatty acid homeostasis(GO:0055089)
1.2 13.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.2 1.2 GO:1902961 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.1 13.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.1 13.7 GO:0006108 malate metabolic process(GO:0006108)
1.1 13.7 GO:0006657 CDP-choline pathway(GO:0006657)
1.1 6.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.1 10.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.1 4.5 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
1.1 11.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.1 16.8 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.1 25.8 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
1.1 2.2 GO:0006907 pinocytosis(GO:0006907)
1.1 13.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
1.1 6.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.1 3.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.1 10.8 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
1.1 7.5 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.1 3.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.1 2.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
1.1 3.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.1 12.7 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
1.0 5.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
1.0 9.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.0 8.2 GO:0006531 aspartate metabolic process(GO:0006531)
1.0 4.1 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
1.0 19.0 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
1.0 3.0 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.0 3.0 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
1.0 2.0 GO:0031133 regulation of axon diameter(GO:0031133)
1.0 4.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.0 4.9 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.0 2.9 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.0 6.7 GO:2000773 negative regulation of cellular senescence(GO:2000773)
1.0 1.9 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.9 0.9 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.9 67.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.9 8.4 GO:0070459 prolactin secretion(GO:0070459)
0.9 9.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.9 8.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.9 40.6 GO:0035036 sperm-egg recognition(GO:0035036)
0.9 21.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.9 2.7 GO:1990535 neuron projection maintenance(GO:1990535)
0.9 6.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.9 8.8 GO:0015889 cobalamin transport(GO:0015889)
0.9 1.7 GO:0070827 chromatin maintenance(GO:0070827)
0.8 4.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.8 3.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.8 7.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.8 6.7 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.8 1.7 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.8 7.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.8 9.8 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.8 3.2 GO:0042182 ketone catabolic process(GO:0042182)
0.8 2.4 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.8 8.7 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.8 6.4 GO:0006836 neurotransmitter transport(GO:0006836)
0.8 14.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.8 29.0 GO:0030517 negative regulation of axon extension(GO:0030517)
0.8 6.3 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8 12.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.8 14.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.8 2.3 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.8 3.1 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.8 1.5 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.8 3.8 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.8 18.9 GO:0007628 adult walking behavior(GO:0007628)
0.8 16.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.7 45.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.7 8.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.7 2.2 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.7 4.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.7 5.2 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.7 3.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.7 20.7 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.7 0.7 GO:0060157 urinary bladder development(GO:0060157)
0.7 3.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.7 2.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.7 2.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.7 2.2 GO:0060174 limb bud formation(GO:0060174)
0.7 15.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.7 10.7 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.7 8.6 GO:0030238 male sex determination(GO:0030238)
0.7 2.8 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.7 2.1 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.7 2.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.7 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.7 26.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.7 2.7 GO:0042412 taurine biosynthetic process(GO:0042412)
0.7 68.0 GO:0007286 spermatid development(GO:0007286)
0.7 8.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.7 2.0 GO:0035936 testosterone secretion(GO:0035936) regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.6 1.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.6 5.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.6 14.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.6 9.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.6 4.5 GO:0060068 vagina development(GO:0060068)
0.6 2.5 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.6 12.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.6 5.0 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6 1.9 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.6 1.9 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.6 1.8 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.6 11.0 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.6 7.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.6 4.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.6 3.0 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.6 4.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6 15.7 GO:0097178 ruffle assembly(GO:0097178)
0.6 5.4 GO:0006069 ethanol oxidation(GO:0006069)
0.6 4.2 GO:0070375 ERK5 cascade(GO:0070375)
0.6 13.8 GO:0016578 histone deubiquitination(GO:0016578)
0.6 3.0 GO:0016236 macroautophagy(GO:0016236)
0.6 4.8 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.6 12.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.6 2.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.6 10.6 GO:0060736 prostate gland growth(GO:0060736)
0.6 1.8 GO:0070781 response to biotin(GO:0070781)
0.6 2.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.6 6.4 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.6 8.1 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.6 2.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.6 2.3 GO:1990403 embryonic brain development(GO:1990403)
0.6 20.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.6 1.7 GO:0060718 negative regulation of cytokinesis(GO:0032466) chorionic trophoblast cell differentiation(GO:0060718)
0.6 3.4 GO:1903760 regulation of potassium ion export(GO:1902302) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.6 3.4 GO:0035799 ureter maturation(GO:0035799)
0.6 1.1 GO:1902623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.6 2.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031) positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.6 39.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.6 1.1 GO:0060290 transdifferentiation(GO:0060290)
0.5 2.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.5 1.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.5 2.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.5 2.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.5 9.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.5 1.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.5 3.8 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 1.6 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.5 8.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.5 1.6 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.5 13.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.5 2.0 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.5 3.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.5 11.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.5 7.6 GO:0015671 oxygen transport(GO:0015671)
0.5 1.0 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.5 11.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.5 36.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 10.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.5 4.4 GO:0048820 hair follicle maturation(GO:0048820)
0.5 1.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.5 25.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.5 3.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.5 2.9 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.5 17.0 GO:0014047 glutamate secretion(GO:0014047)
0.5 2.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.5 11.8 GO:0097503 sialylation(GO:0097503)
0.5 5.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 3.6 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.4 4.0 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.4 8.9 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4 1.3 GO:0061333 renal tubule morphogenesis(GO:0061333) nephron epithelium development(GO:0072009) nephron morphogenesis(GO:0072028)
0.4 16.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.4 1.8 GO:0043473 pigmentation(GO:0043473)
0.4 11.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.4 1.7 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.4 8.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 14.0 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.4 6.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.4 28.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.4 6.7 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.4 1.3 GO:0021553 olfactory nerve development(GO:0021553)
0.4 2.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 13.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 7.4 GO:0050919 negative chemotaxis(GO:0050919)
0.4 5.7 GO:0001935 endothelial cell proliferation(GO:0001935)
0.4 1.6 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.4 2.5 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.4 2.9 GO:0042426 choline catabolic process(GO:0042426)
0.4 4.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 5.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 4.0 GO:0042634 regulation of hair cycle(GO:0042634)
0.4 5.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.4 1.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 7.6 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.4 7.6 GO:0071420 cellular response to histamine(GO:0071420)
0.4 2.3 GO:0043366 beta selection(GO:0043366)
0.4 1.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.4 2.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.4 3.7 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.4 26.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.4 3.7 GO:0035330 regulation of hippo signaling(GO:0035330)
0.4 4.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.4 5.8 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.4 17.0 GO:0048477 oogenesis(GO:0048477)
0.4 2.1 GO:0018343 protein farnesylation(GO:0018343)
0.4 14.8 GO:0042073 intraciliary transport(GO:0042073)
0.4 2.5 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.4 3.5 GO:0099612 protein localization to axon(GO:0099612)
0.3 8.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.3 11.8 GO:0030279 negative regulation of ossification(GO:0030279)
0.3 6.5 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.3 1.4 GO:0071630 trophectodermal cellular morphogenesis(GO:0001831) nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3 6.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.3 0.7 GO:0043132 NAD transport(GO:0043132)
0.3 1.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.3 3.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 4.2 GO:0036376 sodium ion export from cell(GO:0036376)
0.3 7.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.3 6.7 GO:0030488 tRNA methylation(GO:0030488)
0.3 5.5 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.3 0.6 GO:0060574 columnar/cuboidal epithelial cell maturation(GO:0002069) intestinal epithelial cell maturation(GO:0060574)
0.3 0.9 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.3 1.6 GO:1901160 serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.3 9.0 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.3 0.3 GO:1903416 response to glycoside(GO:1903416)
0.3 5.8 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.3 4.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 4.0 GO:0009584 detection of visible light(GO:0009584)
0.3 6.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.3 13.6 GO:1903146 regulation of mitophagy(GO:1903146)
0.3 1.2 GO:0030432 peristalsis(GO:0030432)
0.3 3.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.3 1.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 1.8 GO:0051597 response to methylmercury(GO:0051597)
0.3 1.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 6.9 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.3 0.6 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of neurotransmitter transport(GO:0051590) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.3 0.6 GO:0060324 face development(GO:0060324)
0.3 11.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.3 5.0 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3 5.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 14.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3 4.5 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.3 3.2 GO:0030509 BMP signaling pathway(GO:0030509)
0.3 13.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.3 2.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.3 1.6 GO:0008343 adult feeding behavior(GO:0008343)
0.3 1.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.3 3.1 GO:0048265 response to pain(GO:0048265)
0.3 1.3 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.2 10.7 GO:0030500 regulation of bone mineralization(GO:0030500)
0.2 2.7 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.2 2.2 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.2 3.6 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2 2.4 GO:0001553 luteinization(GO:0001553)
0.2 3.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 4.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.2 9.9 GO:0006513 protein monoubiquitination(GO:0006513)
0.2 4.8 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.2 5.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.2 2.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 3.7 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.2 4.5 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2 3.6 GO:0001502 cartilage condensation(GO:0001502)
0.2 5.3 GO:0007520 myoblast fusion(GO:0007520)
0.2 5.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 5.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 2.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 8.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 0.8 GO:0000076 DNA replication checkpoint(GO:0000076)
0.2 4.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 0.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 4.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 2.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 0.4 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.2 4.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.2 2.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.2 2.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 10.1 GO:0019233 sensory perception of pain(GO:0019233)
0.2 32.4 GO:0007601 visual perception(GO:0007601)
0.2 1.3 GO:0044266 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.2 2.0 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2 18.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2 8.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.2 4.3 GO:0072337 modified amino acid transport(GO:0072337)
0.2 0.5 GO:0019448 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.2 0.7 GO:0045003 meiotic DNA recombinase assembly(GO:0000707) DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.2 3.5 GO:0007099 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.2 3.6 GO:0006400 tRNA modification(GO:0006400)
0.2 12.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 2.4 GO:0060384 innervation(GO:0060384)
0.2 1.2 GO:0016322 neuron remodeling(GO:0016322)
0.2 2.4 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.6 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.2 1.1 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2 1.9 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.2 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 2.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 3.1 GO:0031648 protein destabilization(GO:0031648)
0.2 2.3 GO:0048483 autonomic nervous system development(GO:0048483)
0.2 0.3 GO:0035814 negative regulation of urine volume(GO:0035811) negative regulation of renal sodium excretion(GO:0035814)
0.1 1.8 GO:0007097 nuclear migration(GO:0007097)
0.1 2.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.6 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 1.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 1.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 5.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.1 GO:0072708 response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709)
0.1 1.9 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.6 GO:0015791 polyol transport(GO:0015791)
0.1 0.9 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.9 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1 1.7 GO:0042737 drug catabolic process(GO:0042737)
0.1 0.5 GO:0071389 cellular response to corticosterone stimulus(GO:0071386) cellular response to mineralocorticoid stimulus(GO:0071389)
0.1 2.5 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 1.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 65.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 2.0 GO:0043030 regulation of macrophage activation(GO:0043030)
0.1 1.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 3.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 3.2 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 4.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.3 GO:1990173 establishment of protein localization to telomere(GO:0070200) regulation of establishment of protein localization to telomere(GO:0070203) scaRNA localization to Cajal body(GO:0090666) protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 1.8 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1 2.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.3 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 2.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 1.1 GO:0032196 transposition(GO:0032196)
0.1 5.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.5 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.1 1.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.8 GO:0015074 DNA integration(GO:0015074)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.0 GO:0042552 myelination(GO:0042552)
0.1 0.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 2.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.6 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 1.6 GO:1904029 regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.4 GO:0071875 adrenergic receptor signaling pathway(GO:0071875) adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.7 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 1.6 GO:1901998 toxin transport(GO:1901998)
0.1 1.6 GO:0097576 vacuole fusion(GO:0097576)
0.1 0.9 GO:0030220 platelet formation(GO:0030220)
0.1 1.3 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.1 0.7 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.3 GO:0021892 cerebral cortex GABAergic interneuron differentiation(GO:0021892) cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 1.2 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.9 GO:0070849 response to epidermal growth factor(GO:0070849)
0.1 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 10.8 GO:0006470 protein dephosphorylation(GO:0006470)
0.1 0.1 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 2.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 23.7 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 2.2 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.9 GO:0030282 bone mineralization(GO:0030282)
0.0 0.8 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.2 GO:0003341 cilium movement(GO:0003341)
0.0 0.5 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 38.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
9.5 28.6 GO:0043198 dendritic shaft(GO:0043198)
9.2 36.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
8.6 42.9 GO:0071546 pi-body(GO:0071546)
8.5 67.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
8.3 66.7 GO:0033391 chromatoid body(GO:0033391)
7.0 7.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
6.3 75.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
6.0 23.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
4.7 23.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
4.2 16.8 GO:0044611 nuclear pore inner ring(GO:0044611)
4.2 16.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
4.1 24.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
3.9 51.2 GO:0030897 HOPS complex(GO:0030897)
3.8 11.5 GO:0019034 viral replication complex(GO:0019034)
3.8 19.2 GO:0033263 CORVET complex(GO:0033263)
3.7 14.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
3.7 11.0 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
3.5 13.9 GO:0030896 checkpoint clamp complex(GO:0030896)
3.3 10.0 GO:0044305 calyx of Held(GO:0044305)
3.3 13.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
3.3 19.9 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
3.2 16.2 GO:0089701 U2AF(GO:0089701)
3.2 22.4 GO:0044326 dendritic spine neck(GO:0044326)
3.1 101.0 GO:0000795 synaptonemal complex(GO:0000795)
2.8 13.8 GO:0070847 core mediator complex(GO:0070847)
2.7 5.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
2.6 23.6 GO:0005827 polar microtubule(GO:0005827)
2.6 43.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
2.6 20.5 GO:0036157 outer dynein arm(GO:0036157)
2.5 17.3 GO:0035371 microtubule plus-end(GO:0035371)
2.5 41.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
2.3 23.3 GO:0097433 dense body(GO:0097433)
2.3 11.6 GO:0044308 axonal spine(GO:0044308)
2.3 6.9 GO:0098536 deuterosome(GO:0098536)
2.3 11.3 GO:0044530 supraspliceosomal complex(GO:0044530)
2.2 13.3 GO:0032444 activin responsive factor complex(GO:0032444)
2.1 8.5 GO:0035838 growing cell tip(GO:0035838)
2.1 14.6 GO:0072487 MSL complex(GO:0072487)
2.0 14.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.9 5.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.9 13.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.9 3.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.8 12.7 GO:0001520 outer dense fiber(GO:0001520)
1.8 22.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.7 5.2 GO:0000439 core TFIIH complex(GO:0000439)
1.7 32.5 GO:0097225 sperm midpiece(GO:0097225)
1.7 11.8 GO:1990635 proximal dendrite(GO:1990635)
1.7 90.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.6 7.9 GO:0032389 MutLalpha complex(GO:0032389)
1.6 25.1 GO:0031045 dense core granule(GO:0031045)
1.6 1.6 GO:1990769 proximal neuron projection(GO:1990769)
1.6 18.7 GO:0043203 axon hillock(GO:0043203)
1.5 4.5 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.4 9.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.4 38.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
1.3 7.9 GO:0032010 phagolysosome(GO:0032010)
1.3 9.1 GO:0097452 GAIT complex(GO:0097452)
1.3 8.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
1.2 30.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.2 1.2 GO:0036020 endolysosome membrane(GO:0036020)
1.2 5.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.1 9.0 GO:0044294 dendritic growth cone(GO:0044294)
1.1 20.0 GO:0005922 connexon complex(GO:0005922)
1.1 2.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
1.1 19.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.0 10.3 GO:0070938 contractile ring(GO:0070938)
1.0 5.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.0 8.6 GO:0042788 polysomal ribosome(GO:0042788)
0.9 10.2 GO:0000243 commitment complex(GO:0000243)
0.9 7.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.9 4.6 GO:0036128 CatSper complex(GO:0036128)
0.9 15.4 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.9 8.0 GO:0032039 integrator complex(GO:0032039)
0.9 43.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.8 3.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.8 5.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 14.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.8 20.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.8 11.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.7 37.0 GO:0016235 aggresome(GO:0016235)
0.7 41.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.7 18.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.7 3.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.7 15.3 GO:0031143 pseudopodium(GO:0031143)
0.7 13.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.7 5.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.6 10.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 3.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.6 6.2 GO:0042587 glycogen granule(GO:0042587)
0.6 3.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 4.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.6 5.9 GO:0044327 dendritic spine head(GO:0044327)
0.6 2.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.6 13.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 8.8 GO:0016461 unconventional myosin complex(GO:0016461)
0.5 4.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 1.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.5 15.0 GO:0031527 filopodium membrane(GO:0031527)
0.5 13.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.5 8.3 GO:0043235 receptor complex(GO:0043235)
0.5 4.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 6.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 12.9 GO:0002080 acrosomal membrane(GO:0002080)
0.5 3.8 GO:0035976 AP1 complex(GO:0035976)
0.5 1.9 GO:0045179 apical cortex(GO:0045179)
0.5 50.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.5 3.7 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.5 1.8 GO:0043293 apoptosome(GO:0043293)
0.4 10.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 45.7 GO:0005814 centriole(GO:0005814)
0.4 2.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 7.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 6.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 12.7 GO:0016592 mediator complex(GO:0016592)
0.4 12.7 GO:0042101 T cell receptor complex(GO:0042101)
0.4 15.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.4 3.5 GO:0060077 inhibitory synapse(GO:0060077)
0.4 13.8 GO:0009925 basal plasma membrane(GO:0009925)
0.4 1.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.4 13.0 GO:0048786 presynaptic active zone(GO:0048786)
0.4 10.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.3 1.4 GO:0032279 asymmetric synapse(GO:0032279)
0.3 5.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 25.0 GO:0016459 myosin complex(GO:0016459)
0.3 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 9.6 GO:0032590 dendrite membrane(GO:0032590)
0.3 3.4 GO:0033268 node of Ranvier(GO:0033268)
0.3 44.5 GO:0055037 recycling endosome(GO:0055037)
0.3 6.9 GO:0044306 neuron projection terminus(GO:0044306)
0.3 1.8 GO:0061617 MICOS complex(GO:0061617)
0.3 18.7 GO:0005802 trans-Golgi network(GO:0005802)
0.3 16.8 GO:0030175 filopodium(GO:0030175)
0.3 14.2 GO:0005801 cis-Golgi network(GO:0005801)
0.3 3.0 GO:0043083 synaptic cleft(GO:0043083)
0.3 3.2 GO:0031082 BLOC complex(GO:0031082)
0.3 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 0.8 GO:0070876 SOSS complex(GO:0070876)
0.2 5.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 14.8 GO:0005770 late endosome(GO:0005770)
0.2 1.4 GO:0043196 varicosity(GO:0043196)
0.2 4.5 GO:0097546 ciliary base(GO:0097546)
0.2 7.7 GO:0030315 T-tubule(GO:0030315)
0.2 1.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 10.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 9.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 3.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 43.4 GO:0001726 ruffle(GO:0001726)
0.2 2.9 GO:0005652 nuclear lamina(GO:0005652)
0.2 2.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 13.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 4.8 GO:0005929 cilium(GO:0005929)
0.2 1.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 129.7 GO:0045202 synapse(GO:0045202)
0.2 2.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 4.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 1.9 GO:0044447 axoneme part(GO:0044447)
0.2 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 9.9 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 2.2 GO:0034451 centriolar satellite(GO:0034451)
0.2 4.9 GO:0070461 SAGA-type complex(GO:0070461)
0.2 16.5 GO:0005903 brush border(GO:0005903)
0.2 1.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 1.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 14.8 GO:0031514 motile cilium(GO:0031514)
0.2 38.4 GO:0045121 membrane raft(GO:0045121)
0.1 1.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 16.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 2.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 4.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.7 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 2.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 14.5 GO:0034399 nuclear periphery(GO:0034399)
0.1 21.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.5 GO:0005795 Golgi stack(GO:0005795)
0.1 1.0 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 3.6 GO:0042383 sarcolemma(GO:0042383)
0.1 2.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 4.9 GO:0043204 perikaryon(GO:0043204)
0.1 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.1 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 10.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.3 GO:0000346 transcription export complex(GO:0000346)
0.1 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 27.0 GO:0016607 nuclear speck(GO:0016607)
0.1 14.6 GO:0043025 neuronal cell body(GO:0043025)
0.1 0.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 24.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.4 GO:0030424 axon(GO:0030424)
0.1 2.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 27.8 GO:0005815 microtubule organizing center(GO:0005815)
0.1 4.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 3.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 4.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 65.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
26.5 132.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
15.9 63.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
13.1 39.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
11.5 68.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
10.1 30.2 GO:0004802 transketolase activity(GO:0004802)
9.7 29.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
9.2 36.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
8.8 96.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
7.9 23.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
7.8 23.4 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
7.6 167.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
7.5 22.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
6.8 20.5 GO:0034584 piRNA binding(GO:0034584)
6.8 27.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
6.1 18.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
6.0 48.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
5.7 17.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
5.7 17.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
5.6 16.8 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
5.2 15.6 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
4.7 19.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
4.7 14.1 GO:0019961 interferon binding(GO:0019961)
4.6 23.0 GO:0070097 delta-catenin binding(GO:0070097)
4.4 39.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
4.3 25.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
4.2 16.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
4.1 24.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
4.0 12.0 GO:0004103 choline kinase activity(GO:0004103)
3.8 11.5 GO:0005137 interleukin-5 receptor binding(GO:0005137)
3.8 11.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
3.8 11.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
3.7 58.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
3.7 11.0 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
3.6 7.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
3.5 10.6 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
3.5 17.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
3.5 27.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
3.4 20.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
3.4 20.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
3.4 10.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
3.3 9.8 GO:0061663 NEDD8 ligase activity(GO:0061663)
3.2 16.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
3.2 9.6 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
3.2 9.6 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
3.2 28.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
3.1 24.7 GO:0004565 beta-galactosidase activity(GO:0004565)
3.1 30.8 GO:0009374 biotin binding(GO:0009374)
3.1 12.3 GO:0035939 microsatellite binding(GO:0035939)
2.9 11.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.9 8.8 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.9 31.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.8 13.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.7 8.2 GO:0098770 FBXO family protein binding(GO:0098770)
2.7 8.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
2.7 13.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.7 8.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
2.7 26.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
2.7 8.0 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
2.7 10.6 GO:0031685 adenosine receptor binding(GO:0031685)
2.7 10.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
2.6 12.9 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
2.5 4.9 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
2.5 4.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
2.5 9.8 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.4 7.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
2.4 40.8 GO:0019992 diacylglycerol binding(GO:0019992)
2.3 30.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
2.3 13.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
2.3 32.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
2.2 60.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
2.1 10.7 GO:0061665 SUMO ligase activity(GO:0061665)
2.1 27.3 GO:0031005 filamin binding(GO:0031005)
2.0 8.1 GO:0004461 lactose synthase activity(GO:0004461)
2.0 4.0 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
2.0 3.9 GO:0070888 E-box binding(GO:0070888)
2.0 19.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.9 9.7 GO:0031893 vasopressin receptor binding(GO:0031893)
1.9 9.6 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.9 5.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.9 5.6 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
1.8 29.2 GO:0097109 neuroligin family protein binding(GO:0097109)
1.8 29.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.8 9.0 GO:0097108 hedgehog family protein binding(GO:0097108)
1.8 25.2 GO:0008179 adenylate cyclase binding(GO:0008179)
1.8 7.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.8 7.0 GO:0019770 IgG receptor activity(GO:0019770)
1.7 7.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.7 3.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.7 24.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
1.7 5.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.7 24.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.7 5.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
1.7 8.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
1.7 6.7 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
1.7 18.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.7 8.4 GO:0052844 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
1.6 16.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.6 4.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.6 64.5 GO:0017025 TBP-class protein binding(GO:0017025)
1.5 15.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.5 18.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.5 3.0 GO:0032767 copper-dependent protein binding(GO:0032767)
1.5 4.5 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.5 7.5 GO:0004995 tachykinin receptor activity(GO:0004995)
1.5 4.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.5 17.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.5 25.1 GO:0015250 water channel activity(GO:0015250)
1.4 8.6 GO:0032407 MutSalpha complex binding(GO:0032407)
1.4 4.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
1.4 6.9 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
1.4 11.0 GO:0004957 prostaglandin E receptor activity(GO:0004957)
1.4 39.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.3 30.9 GO:0004383 guanylate cyclase activity(GO:0004383)
1.3 8.0 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
1.3 18.7 GO:0004065 arylsulfatase activity(GO:0004065)
1.3 8.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.2 13.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.2 37.2 GO:0017075 syntaxin-1 binding(GO:0017075)
1.2 4.9 GO:0008384 IkappaB kinase activity(GO:0008384)
1.2 34.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.2 9.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.2 4.7 GO:0070087 chromo shadow domain binding(GO:0070087)
1.1 5.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.1 28.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.1 3.3 GO:1904288 BAT3 complex binding(GO:1904288)
1.1 40.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.1 4.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.1 2.2 GO:0034511 U3 snoRNA binding(GO:0034511)
1.1 2.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
1.1 20.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
1.1 3.2 GO:0070538 oleic acid binding(GO:0070538)
1.1 12.7 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
1.0 10.4 GO:0005243 gap junction channel activity(GO:0005243)
1.0 20.5 GO:0045504 dynein heavy chain binding(GO:0045504)
1.0 11.1 GO:0051525 NFAT protein binding(GO:0051525)
1.0 5.0 GO:0008420 CTD phosphatase activity(GO:0008420)
1.0 4.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
1.0 5.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.0 8.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.0 2.9 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.0 3.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.0 4.8 GO:0008174 mRNA methyltransferase activity(GO:0008174)
1.0 2.9 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.9 10.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.9 5.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.9 31.3 GO:0070840 dynein complex binding(GO:0070840)
0.9 33.0 GO:0005109 frizzled binding(GO:0005109)
0.9 3.7 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.9 13.5 GO:0015643 toxic substance binding(GO:0015643)
0.9 48.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.9 11.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.9 15.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.9 3.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 17.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.9 14.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.8 2.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.8 2.5 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.8 10.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.8 55.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.8 29.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.8 79.0 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.8 15.9 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.7 13.5 GO:0005522 profilin binding(GO:0005522)
0.7 2.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.7 3.0 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.7 8.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.7 1.5 GO:1990763 arrestin family protein binding(GO:1990763)
0.7 5.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.7 2.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.7 1.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.7 9.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 15.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.7 11.0 GO:0042923 neuropeptide binding(GO:0042923)
0.7 11.6 GO:0004659 prenyltransferase activity(GO:0004659)
0.7 2.7 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.7 2.7 GO:0043559 insulin binding(GO:0043559)
0.6 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.6 8.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.6 12.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.6 0.6 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.6 2.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.6 3.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.6 1.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.6 2.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.6 1.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.6 3.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.6 7.7 GO:0031432 titin binding(GO:0031432)
0.6 3.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.6 5.9 GO:0043495 protein anchor(GO:0043495)
0.6 2.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.6 18.8 GO:0015248 sterol transporter activity(GO:0015248)
0.6 6.4 GO:0051434 BH3 domain binding(GO:0051434)
0.6 7.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.6 21.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.6 3.4 GO:0045499 chemorepellent activity(GO:0045499)
0.6 4.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.5 2.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.5 2.2 GO:0071253 connexin binding(GO:0071253)
0.5 1.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 9.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.5 1.6 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.5 3.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.5 11.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.5 15.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.5 4.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.5 23.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.5 14.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 12.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.5 32.7 GO:0035064 methylated histone binding(GO:0035064)
0.5 12.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.5 5.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.5 4.9 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.5 11.6 GO:0005521 lamin binding(GO:0005521)
0.5 10.0 GO:0032451 demethylase activity(GO:0032451)
0.5 3.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.5 7.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 1.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.5 11.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 4.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.5 3.6 GO:0034235 GPI anchor binding(GO:0034235)
0.4 11.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 5.3 GO:0019864 IgG binding(GO:0019864)
0.4 19.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.4 18.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 6.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.4 2.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.4 28.7 GO:0019905 syntaxin binding(GO:0019905)
0.4 1.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.4 14.9 GO:0070412 R-SMAD binding(GO:0070412)
0.4 100.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.4 4.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.4 2.9 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 4.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 8.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 23.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.4 2.4 GO:0003696 satellite DNA binding(GO:0003696)
0.4 1.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 3.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 1.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.4 2.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 1.1 GO:0070728 leucine binding(GO:0070728)
0.4 4.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 141.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 1.4 GO:0043426 MRF binding(GO:0043426)
0.3 2.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 3.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 7.0 GO:0008066 glutamate receptor activity(GO:0008066)
0.3 1.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 3.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3 8.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.9 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3 8.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 3.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 2.2 GO:0034452 dynactin binding(GO:0034452)
0.3 3.4 GO:0097016 L27 domain binding(GO:0097016)
0.3 2.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 3.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.3 3.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 13.1 GO:0030507 spectrin binding(GO:0030507)
0.3 6.8 GO:0042169 SH2 domain binding(GO:0042169)
0.3 1.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.3 5.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.3 11.7 GO:0003785 actin monomer binding(GO:0003785)
0.3 7.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 18.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.3 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 2.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 0.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 4.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.3 9.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 4.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 33.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 3.0 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 4.7 GO:0051184 cofactor transporter activity(GO:0051184)
0.2 2.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 1.9 GO:0010181 FMN binding(GO:0010181)
0.2 5.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 36.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 25.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 13.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 71.3 GO:0005096 GTPase activator activity(GO:0005096)
0.2 21.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 3.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 42.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 8.4 GO:0030552 cAMP binding(GO:0030552)
0.2 4.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 8.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 1.0 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2 8.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 4.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 5.0 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 2.2 GO:0070700 BMP receptor binding(GO:0070700)
0.2 4.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 0.5 GO:1904047 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) S-adenosyl-L-methionine binding(GO:1904047)
0.2 3.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 4.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.2 3.4 GO:0050811 GABA receptor binding(GO:0050811)
0.2 18.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 1.8 GO:0043531 ADP binding(GO:0043531)
0.2 8.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 2.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 2.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 5.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 5.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 16.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 39.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 2.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 2.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 4.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.2 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.4 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 7.9 GO:0005179 hormone activity(GO:0005179)
0.1 8.4 GO:0019902 phosphatase binding(GO:0019902)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.4 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0004952 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.1 2.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 5.2 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 3.8 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.9 GO:0005272 sodium channel activity(GO:0005272)
0.0 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.3 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 2.0 GO:0005506 iron ion binding(GO:0005506)
0.0 0.3 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 56.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.3 44.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.2 8.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
1.2 30.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.1 61.9 PID AURORA A PATHWAY Aurora A signaling
1.1 50.3 PID REELIN PATHWAY Reelin signaling pathway
1.0 24.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.0 14.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.9 14.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.9 19.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.9 24.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.9 16.4 PID IL5 PATHWAY IL5-mediated signaling events
0.9 12.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.8 7.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.7 7.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.7 9.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.7 19.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.6 11.9 PID ALK2 PATHWAY ALK2 signaling events
0.6 25.6 PID RAS PATHWAY Regulation of Ras family activation
0.6 25.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.6 11.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.5 13.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.5 8.6 ST GAQ PATHWAY G alpha q Pathway
0.5 11.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.5 19.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.5 10.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 8.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.5 12.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.4 3.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4 23.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.4 8.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.4 3.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 4.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4 33.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.3 3.8 ST GA12 PATHWAY G alpha 12 Pathway
0.3 14.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 8.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 17.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 3.2 PID EPO PATHWAY EPO signaling pathway
0.3 34.8 PID P73PATHWAY p73 transcription factor network
0.3 17.4 PID PLK1 PATHWAY PLK1 signaling events
0.3 6.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 4.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 12.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 3.5 ST GA13 PATHWAY G alpha 13 Pathway
0.2 12.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 3.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 11.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 2.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 11.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 11.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 3.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 7.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 5.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 3.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 14.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 8.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 4.5 PID FGF PATHWAY FGF signaling pathway
0.1 2.5 PID ARF 3PATHWAY Arf1 pathway
0.1 1.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 5.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.5 PID FOXO PATHWAY FoxO family signaling
0.1 4.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 4.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.4 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 11.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.2 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 101.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
2.4 4.8 REACTOME MRNA CAPPING Genes involved in mRNA Capping
2.0 76.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
1.9 28.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.8 43.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.8 25.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.8 24.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.6 73.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.6 44.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.6 18.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.5 32.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.5 32.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.4 29.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.3 31.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
1.3 25.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
1.3 66.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
1.3 13.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
1.2 10.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.2 17.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
1.1 21.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.1 20.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
1.1 74.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
1.0 51.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
1.0 14.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.9 6.4 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.9 2.7 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.9 23.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.9 13.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.8 74.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.8 9.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.8 13.6 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.7 24.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.7 16.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.7 11.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.7 8.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.7 5.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.7 12.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 10.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.7 19.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.6 14.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6 12.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.6 12.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.6 46.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.6 5.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.6 11.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 11.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.6 14.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 7.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 6.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.5 6.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.5 11.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.5 44.9 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.5 8.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.5 26.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.5 1.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.5 11.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 13.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.5 105.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.5 14.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.4 4.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 9.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.4 4.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 6.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.4 13.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 36.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.4 4.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 8.9 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.4 18.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 3.0 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.4 8.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.4 7.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 11.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 3.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 8.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 2.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.3 7.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.3 13.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.3 9.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.3 11.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 2.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.3 1.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.3 16.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 4.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 6.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 26.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.3 11.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.3 11.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 2.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.3 3.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 4.7 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.3 12.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 4.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 3.1 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
0.2 1.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 17.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 3.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 10.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 4.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 12.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling