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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MXI1_MYC_MYCN

Z-value: 5.35

Motif logo

Transcription factors associated with MXI1_MYC_MYCN

Gene Symbol Gene ID Gene Info
ENSG00000119950.16 MAX interactor 1, dimerization protein
ENSG00000136997.10 MYC proto-oncogene, bHLH transcription factor
ENSG00000134323.10 MYCN proto-oncogene, bHLH transcription factor

Activity-expression correlation:

Activity profile of MXI1_MYC_MYCN motif

Sorted Z-values of MXI1_MYC_MYCN motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58146128 239.34 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr12_-_58146048 238.77 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr11_-_64014379 213.77 ENST00000309318.3
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_10588630 198.46 ENST00000234111.4
ornithine decarboxylase 1
chr19_+_50180409 184.63 ENST00000391851.4
protein arginine methyltransferase 1
chr19_+_50180507 181.90 ENST00000454376.2
ENST00000524771.1
protein arginine methyltransferase 1
chr2_+_216176540 164.98 ENST00000236959.9
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr17_+_49230897 164.65 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr4_+_57302297 162.90 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chrX_+_23685653 161.40 ENST00000379331.3
peroxiredoxin 4
chr4_+_57301896 155.70 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr8_+_55047763 152.16 ENST00000260102.4
ENST00000519831.1
mitochondrial ribosomal protein L15
chr14_+_20923350 148.53 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr2_+_216176761 147.07 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr22_+_20105259 129.06 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr6_-_43197189 129.01 ENST00000509253.1
ENST00000393987.2
ENST00000230431.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr1_+_43148625 127.79 ENST00000436427.1
Y box binding protein 1
chr1_-_11120057 127.51 ENST00000376957.2
spermidine synthase
chr2_+_113403434 122.79 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr8_+_98656336 118.06 ENST00000336273.3
metadherin
chrX_+_23685563 113.84 ENST00000379341.4
peroxiredoxin 4
chr9_+_131452239 110.94 ENST00000372688.4
ENST00000372686.5
SET nuclear oncogene
chr13_+_27998681 105.80 ENST00000381140.4
general transcription factor IIIA
chr3_+_52719936 103.82 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr19_+_50180317 103.33 ENST00000534465.1
protein arginine methyltransferase 1
chr7_+_150759634 98.63 ENST00000392826.2
ENST00000461735.1
solute carrier family 4 (anion exchanger), member 2
chr1_-_26233423 95.59 ENST00000357865.2
stathmin 1
chr19_-_2427863 94.82 ENST00000215570.3
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr1_+_165797024 94.60 ENST00000372212.4
uridine-cytidine kinase 2
chr12_+_57624085 94.56 ENST00000553474.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr19_-_10530784 93.43 ENST00000593124.1
cell division cycle 37
chr1_-_26232951 93.41 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr17_-_47492164 92.44 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
prohibitin
chr17_+_49337881 91.69 ENST00000225298.7
UTP18 small subunit (SSU) processome component homolog (yeast)
chr12_-_49318715 90.49 ENST00000444214.2
FK506 binding protein 11, 19 kDa
chr11_-_64013663 89.81 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr6_-_33385854 88.93 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr2_+_198365122 86.23 ENST00000604458.1
HSPE1-MOB4 readthrough
chr2_+_198365095 86.14 ENST00000409468.1
heat shock 10kDa protein 1
chr12_+_57624119 84.23 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr6_-_17706618 84.20 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr4_-_99850243 82.49 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr19_-_42806723 82.42 ENST00000262890.3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr11_-_122931881 81.55 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr10_+_81107271 80.76 ENST00000448165.1
peptidylprolyl isomerase F
chr20_+_44441304 80.52 ENST00000352551.5
ubiquitin-conjugating enzyme E2C
chr2_-_10587897 80.22 ENST00000405333.1
ENST00000443218.1
ornithine decarboxylase 1
chr17_+_49243792 78.78 ENST00000393183.3
ENST00000393190.1
NME1-NME2 readthrough
chr17_+_49243639 77.64 ENST00000512737.1
ENST00000503064.1
NME1-NME2 readthrough
chr1_-_8938736 76.89 ENST00000234590.4
enolase 1, (alpha)
chr12_+_57623869 76.86 ENST00000414700.3
ENST00000557703.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_-_58893832 76.58 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr8_+_97274119 75.75 ENST00000455950.2
phosphatidylserine synthase 1
chr18_+_12947981 74.89 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr1_-_8939265 74.88 ENST00000489867.1
enolase 1, (alpha)
chr16_-_87903079 74.81 ENST00000261622.4
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr11_+_114310164 74.77 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr20_+_44441215 74.70 ENST00000356455.4
ENST00000405520.1
ubiquitin-conjugating enzyme E2C
chr21_-_46237883 74.23 ENST00000397893.3
small ubiquitin-like modifier 3
chr14_-_58894223 73.89 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr19_-_2427536 73.04 ENST00000591871.1
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr11_+_114310237 72.86 ENST00000539119.1
RNA exonuclease 2
chr6_-_33385655 72.75 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr22_+_20105012 72.63 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr1_-_155232221 72.50 ENST00000355379.3
secretory carrier membrane protein 3
chr6_-_32811771 72.26 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr11_+_114310102 72.07 ENST00000265881.5
RNA exonuclease 2
chr16_-_81129845 70.73 ENST00000569885.1
ENST00000566566.1
glycine cleavage system protein H (aminomethyl carrier)
chr1_-_43638168 70.46 ENST00000431635.2
EBNA1 binding protein 2
chr1_+_19578033 70.32 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr10_-_71993176 69.69 ENST00000373232.3
pyrophosphatase (inorganic) 1
chr6_-_8102714 68.96 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr1_+_165796753 68.41 ENST00000367879.4
uridine-cytidine kinase 2
chr12_+_131356582 67.77 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chr8_+_98656693 67.65 ENST00000519934.1
metadherin
chr12_+_57623477 67.64 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
serine hydroxymethyltransferase 2 (mitochondrial)
chr10_-_120840309 66.42 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr6_-_8102279 66.00 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr7_+_100464760 65.27 ENST00000200457.4
thyroid hormone receptor interactor 6
chr13_+_114238997 65.11 ENST00000538138.1
ENST00000375370.5
transcription factor Dp-1
chr8_+_22224760 65.00 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
solute carrier family 39 (zinc transporter), member 14
chr2_+_27440229 64.76 ENST00000264705.4
ENST00000403525.1
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr1_-_155232047 63.77 ENST00000302631.3
secretory carrier membrane protein 3
chr1_+_111991474 62.74 ENST00000369722.3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr6_-_33385823 62.49 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr12_+_64798095 61.56 ENST00000332707.5
exportin, tRNA
chr17_+_76164639 61.43 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
synaptogyrin 2
chr17_+_42148225 61.40 ENST00000591696.1
glucose 6 phosphatase, catalytic, 3
chr19_-_5719860 61.26 ENST00000590729.1
lon peptidase 1, mitochondrial
chr12_+_66217911 60.65 ENST00000403681.2
high mobility group AT-hook 2
chr17_+_36908984 60.40 ENST00000225426.4
ENST00000579088.1
proteasome (prosome, macropain) subunit, beta type, 3
chr6_-_33385870 59.84 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr17_+_42148097 59.76 ENST00000269097.4
glucose 6 phosphatase, catalytic, 3
chr11_+_844067 59.72 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
tetraspanin 4
chr19_-_5720123 59.18 ENST00000587365.1
ENST00000585374.1
ENST00000593119.1
lon peptidase 1, mitochondrial
chr2_+_131100710 58.65 ENST00000452955.1
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr19_-_42806842 58.36 ENST00000596265.1
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr9_+_112542591 58.10 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr9_-_113018835 57.93 ENST00000374517.5
thioredoxin
chr1_-_43637915 57.85 ENST00000236051.2
EBNA1 binding protein 2
chr17_+_65713925 57.13 ENST00000253247.4
nucleolar protein 11
chr12_+_108079664 57.12 ENST00000541166.1
PWP1 homolog (S. cerevisiae)
chr1_-_159894319 56.91 ENST00000320307.4
transgelin 2
chr13_-_31038370 56.77 ENST00000399489.1
ENST00000339872.4
high mobility group box 1
chr6_+_24775153 56.57 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr1_+_111992064 56.21 ENST00000483994.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr7_-_132766800 55.99 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr19_+_47634039 55.75 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr7_-_132766818 55.73 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr14_-_105487381 55.55 ENST00000392590.3
ENST00000336219.3
cell division cycle associated 4
chr16_-_81129951 55.17 ENST00000315467.3
glycine cleavage system protein H (aminomethyl carrier)
chr16_-_30441293 55.05 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
dCTP pyrophosphatase 1
chr2_+_131100423 55.02 ENST00000409935.1
ENST00000409649.1
ENST00000428740.1
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr9_+_91926103 54.84 ENST00000314355.6
CDC28 protein kinase regulatory subunit 2
chr12_+_104359576 54.23 ENST00000392872.3
ENST00000436021.2
thymine-DNA glycosylase
chr1_+_38478378 54.12 ENST00000373014.4
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr3_-_183967296 54.05 ENST00000455059.1
ENST00000445626.2
ALG3, alpha-1,3- mannosyltransferase
chrX_-_47518498 53.96 ENST00000335890.2
ubiquitously-expressed, prefoldin-like chaperone
chr13_+_76123883 53.95 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr8_-_102217796 53.89 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
zinc finger protein 706
chr17_+_76165213 53.67 ENST00000590201.1
synaptogyrin 2
chr19_+_34855874 53.42 ENST00000588991.2
glucose-6-phosphate isomerase
chr6_+_32811885 53.29 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr19_+_41768401 52.78 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr20_+_31407692 52.48 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chr11_+_60609537 51.67 ENST00000227520.5
coiled-coil domain containing 86
chr1_-_115259337 51.65 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr19_-_40336969 51.24 ENST00000599134.1
ENST00000597634.1
ENST00000598417.1
ENST00000601274.1
ENST00000594309.1
ENST00000221801.3
fibrillarin
chr8_-_97273807 51.07 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERF domain containing 1
chr17_+_7476136 50.82 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr11_+_34127142 50.79 ENST00000257829.3
ENST00000531159.2
N-acetyltransferase 10 (GCN5-related)
chr8_-_117768023 50.71 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chrX_+_48433326 50.70 ENST00000376755.1
RNA binding motif (RNP1, RRM) protein 3
chr17_-_40075219 50.48 ENST00000537919.1
ENST00000352035.2
ENST00000353196.1
ENST00000393896.2
ATP citrate lyase
chr11_-_118972575 50.39 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr3_+_127317066 50.35 ENST00000265056.7
minichromosome maintenance complex component 2
chr2_+_88991162 50.23 ENST00000283646.4
ribose 5-phosphate isomerase A
chr17_-_47492236 50.17 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
prohibitin
chr11_+_9406169 50.12 ENST00000379719.3
ENST00000527431.1
importin 7
chr16_-_88851618 50.03 ENST00000301015.9
piezo-type mechanosensitive ion channel component 1
chr19_-_41903161 49.81 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
exosome component 5
chr17_-_48474828 49.13 ENST00000576448.1
ENST00000225972.7
leucine rich repeat containing 59
chrX_-_47518527 49.11 ENST00000333119.3
ubiquitously-expressed, prefoldin-like chaperone
chr8_+_98788003 48.84 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr9_-_113018746 48.71 ENST00000374515.5
thioredoxin
chr7_-_23510086 48.50 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chrX_-_16887963 48.18 ENST00000380084.4
retinoblastoma binding protein 7
chr11_+_844406 47.95 ENST00000397404.1
tetraspanin 4
chr20_+_35202909 47.89 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr12_+_96252706 47.63 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr10_+_70715884 47.38 ENST00000354185.4
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr10_-_97416400 47.38 ENST00000371224.2
ENST00000371221.3
aldehyde dehydrogenase 18 family, member A1
chr1_+_32479430 47.15 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chr6_-_53213780 47.01 ENST00000304434.6
ENST00000370918.4
ELOVL fatty acid elongase 5
chr6_+_30689401 46.87 ENST00000396389.1
ENST00000396384.1
tubulin, beta class I
chr6_-_33385902 46.82 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr16_-_88878305 46.67 ENST00000569616.1
ENST00000563655.1
ENST00000567713.1
ENST00000426324.2
ENST00000378364.3
adenine phosphoribosyltransferase
chr5_+_172386419 46.61 ENST00000265100.2
ENST00000519239.1
ribosomal protein L26-like 1
chr21_-_46238034 46.27 ENST00000332859.6
small ubiquitin-like modifier 3
chr11_+_18416133 46.20 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
lactate dehydrogenase A
chr17_-_46688334 46.06 ENST00000239165.7
homeobox B7
chr15_+_52311398 46.01 ENST00000261845.5
mitogen-activated protein kinase 6
chr3_-_63849571 45.89 ENST00000295899.5
THO complex 7 homolog (Drosophila)
chr4_-_2935674 45.85 ENST00000514800.1
major facilitator superfamily domain containing 10
chr7_+_16685756 45.84 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
basic leucine zipper and W2 domains 2
chr6_+_44191290 45.67 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_-_40041925 45.34 ENST00000372862.3
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr8_-_103668114 45.26 ENST00000285407.6
Kruppel-like factor 10
chr20_+_23331373 45.07 ENST00000254998.2
NTF2-like export factor 1
chr1_-_78148324 45.05 ENST00000370801.3
ENST00000433749.1
zinc finger, ZZ-type containing 3
chr19_+_5681153 44.78 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr1_+_155178481 44.76 ENST00000368376.3
metaxin 1
chr17_+_40985407 44.74 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr5_-_133340326 44.61 ENST00000425992.1
ENST00000395044.3
ENST00000395047.2
voltage-dependent anion channel 1
chr12_-_56709786 44.59 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
Uncharacterized protein
canopy FGF signaling regulator 2
chr3_-_131221790 44.21 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr17_-_61850894 43.87 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
coiled-coil domain containing 47
chr2_+_187350883 43.80 ENST00000337859.6
zinc finger CCCH-type containing 15
chr21_-_38445470 43.67 ENST00000399098.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr17_-_7590745 43.61 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
tumor protein p53
chr6_-_153304148 43.61 ENST00000229758.3
F-box protein 5
chr6_+_30689350 43.54 ENST00000330914.3
tubulin, beta class I
chr1_-_86174065 43.54 ENST00000370574.3
ENST00000431532.2
zinc finger, HIT-type containing 6
chr6_+_44191507 43.47 ENST00000371724.1
ENST00000371713.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr3_+_133293278 43.36 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr6_-_7911042 43.27 ENST00000379757.4
thioredoxin domain containing 5 (endoplasmic reticulum)
chr9_-_2844058 43.26 ENST00000397885.2
KIAA0020
chr10_-_16859361 43.19 ENST00000377921.3
Ras suppressor protein 1
chr10_+_75910960 43.15 ENST00000539909.1
ENST00000286621.2
adenosine kinase
chr2_-_175113088 42.96 ENST00000409546.1
ENST00000428402.2
Obg-like ATPase 1
chr14_-_54908043 42.93 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr9_-_95087838 42.74 ENST00000442668.2
ENST00000421075.2
ENST00000536624.1
nucleolar protein 8
chr9_-_95087604 42.70 ENST00000542613.1
ENST00000542053.1
ENST00000358855.4
ENST00000545558.1
ENST00000432670.2
ENST00000433029.2
ENST00000411621.2
nucleolar protein 8
chrX_-_153285251 42.63 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr3_-_49066811 42.62 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr12_+_109535923 42.40 ENST00000336865.2
uracil-DNA glycosylase
chr1_-_6259613 42.25 ENST00000465387.1
ribosomal protein L22
chr20_-_49547910 42.22 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr11_-_47664072 42.12 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
mitochondrial carrier 2
chr11_-_57298187 42.10 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of MXI1_MYC_MYCN

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
95.6 478.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
78.0 312.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
76.6 459.4 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
69.7 278.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
58.9 294.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
52.4 367.0 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
51.1 153.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
50.5 252.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
49.5 148.5 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
49.3 394.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
43.5 391.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
40.8 163.0 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
37.6 112.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
37.6 112.7 GO:0044209 AMP salvage(GO:0044209)
31.0 155.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
30.7 122.8 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
30.3 90.9 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
27.5 55.0 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
26.9 80.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
26.4 26.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
25.4 76.3 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
25.4 50.8 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
25.4 126.8 GO:0031126 snoRNA 3'-end processing(GO:0031126)
25.0 74.9 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
24.4 122.0 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
24.2 72.7 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
23.8 142.6 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
23.2 69.7 GO:0071344 diphosphate metabolic process(GO:0071344)
23.0 184.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
22.3 66.8 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
22.1 66.4 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
22.0 109.8 GO:0015862 uridine transport(GO:0015862)
21.8 43.5 GO:0048254 snoRNA localization(GO:0048254)
20.9 104.7 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
20.0 59.9 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
19.8 138.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
19.7 137.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
19.5 136.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
19.3 192.6 GO:0018202 peptidyl-histidine modification(GO:0018202)
19.3 57.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
19.2 95.8 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
18.7 187.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
18.6 74.3 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
18.4 147.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
17.3 121.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
17.3 69.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
17.0 34.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
16.4 49.3 GO:0046098 guanine metabolic process(GO:0046098)
16.2 48.7 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
15.8 47.3 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
15.7 125.9 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
15.5 62.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
15.3 30.5 GO:0006597 spermine biosynthetic process(GO:0006597)
15.2 45.6 GO:0006014 D-ribose metabolic process(GO:0006014)
15.1 60.5 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
15.0 74.8 GO:0061198 fungiform papilla formation(GO:0061198)
14.9 59.7 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
14.6 73.1 GO:0019640 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
14.5 57.9 GO:1902903 regulation of fibril organization(GO:1902903)
14.3 14.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
14.3 99.9 GO:0008295 spermidine biosynthetic process(GO:0008295)
14.2 28.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
14.2 56.8 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
14.2 269.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
14.1 84.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
14.1 56.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
13.9 41.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
13.7 41.1 GO:0035978 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
13.6 40.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
13.6 40.8 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
13.4 120.7 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
13.4 80.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
13.3 26.6 GO:0044416 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
13.1 26.3 GO:0016074 snoRNA metabolic process(GO:0016074)
13.1 65.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
12.9 38.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
12.8 12.8 GO:1901856 negative regulation of cellular respiration(GO:1901856)
12.3 196.8 GO:0002192 IRES-dependent translational initiation(GO:0002192)
12.3 36.8 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
12.3 122.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
12.3 36.8 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
12.2 48.8 GO:0006218 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
12.1 48.4 GO:1902570 protein localization to nucleolus(GO:1902570)
11.9 107.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
11.9 83.1 GO:0002190 cap-independent translational initiation(GO:0002190)
11.8 47.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
11.7 70.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
11.7 23.5 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
11.6 69.6 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
11.3 34.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
11.3 33.9 GO:1901873 regulation of post-translational protein modification(GO:1901873)
11.0 21.9 GO:0042256 mature ribosome assembly(GO:0042256)
10.9 21.9 GO:0006344 maintenance of chromatin silencing(GO:0006344)
10.8 140.7 GO:0006089 lactate metabolic process(GO:0006089)
10.7 107.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
10.6 265.5 GO:0006999 nuclear pore organization(GO:0006999)
10.5 41.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
10.3 31.0 GO:0046294 formaldehyde catabolic process(GO:0046294)
10.2 30.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
10.2 61.0 GO:0022614 membrane to membrane docking(GO:0022614)
10.2 60.9 GO:0006177 GMP biosynthetic process(GO:0006177)
9.9 39.8 GO:0043335 protein unfolding(GO:0043335)
9.9 9.9 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
9.9 19.8 GO:0019322 pentose-phosphate shunt, oxidative branch(GO:0009051) pentose biosynthetic process(GO:0019322)
9.9 406.0 GO:0042407 cristae formation(GO:0042407)
9.9 39.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
9.9 148.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
9.9 49.3 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
9.8 19.7 GO:0002572 pro-T cell differentiation(GO:0002572)
9.8 49.1 GO:0019348 dolichol metabolic process(GO:0019348)
9.7 19.4 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
9.7 48.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
9.6 57.8 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
9.5 28.6 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
9.5 9.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
9.5 75.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
9.5 66.2 GO:0042113 B cell activation(GO:0042113)
9.4 18.8 GO:0016321 female meiosis chromosome segregation(GO:0016321)
9.4 122.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
9.4 28.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
9.4 28.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
9.3 27.9 GO:0048627 myoblast development(GO:0048627)
9.1 18.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
9.1 9.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
9.0 17.9 GO:0044211 CTP salvage(GO:0044211)
8.9 26.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
8.9 142.0 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
8.8 35.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
8.7 26.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
8.6 86.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
8.5 59.7 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
8.4 41.9 GO:0006740 NADPH regeneration(GO:0006740)
8.4 41.8 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
8.4 58.5 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
8.2 98.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
8.1 81.3 GO:0045008 depyrimidination(GO:0045008)
8.1 558.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
8.1 8.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
8.0 23.9 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
7.9 71.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
7.9 55.4 GO:0033484 nitric oxide homeostasis(GO:0033484)
7.8 47.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
7.7 30.7 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
7.6 45.4 GO:0001887 selenium compound metabolic process(GO:0001887)
7.5 59.7 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
7.5 29.8 GO:0007144 female meiosis I(GO:0007144)
7.5 149.1 GO:0006337 nucleosome disassembly(GO:0006337)
7.4 22.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
7.3 51.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
7.3 87.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
7.2 29.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
7.2 519.9 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
7.2 28.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
7.1 21.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
7.1 42.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
6.9 20.8 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
6.9 20.8 GO:0006738 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
6.9 20.7 GO:0010628 positive regulation of gene expression(GO:0010628)
6.7 67.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
6.7 100.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
6.7 20.0 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
6.6 111.7 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
6.6 32.8 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
6.5 19.6 GO:1902822 lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
6.5 45.7 GO:0015755 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
6.5 13.0 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
6.5 32.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
6.5 45.2 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
6.4 38.7 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
6.4 25.7 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
6.4 12.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
6.4 44.9 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
6.4 280.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
6.4 25.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
6.2 18.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
6.1 30.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
6.1 18.4 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
6.1 90.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
6.1 78.7 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
6.0 259.4 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
6.0 18.0 GO:0040012 regulation of locomotion(GO:0040012)
6.0 42.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
6.0 12.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
6.0 17.9 GO:0006550 isoleucine catabolic process(GO:0006550)
5.9 17.8 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
5.9 29.6 GO:0007008 outer mitochondrial membrane organization(GO:0007008)
5.8 17.5 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
5.8 115.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
5.8 17.4 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
5.7 17.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
5.7 17.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
5.7 11.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
5.7 537.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
5.6 89.9 GO:0006107 oxaloacetate metabolic process(GO:0006107)
5.6 16.8 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
5.5 16.5 GO:0014736 negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876)
5.5 21.8 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
5.4 21.8 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
5.4 21.8 GO:0021564 vagus nerve development(GO:0021564)
5.4 10.7 GO:0015920 lipopolysaccharide transport(GO:0015920)
5.3 10.6 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
5.2 187.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
5.2 20.8 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
5.2 15.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
5.2 20.6 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
5.2 20.6 GO:0009956 radial pattern formation(GO:0009956)
5.1 162.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
5.1 15.2 GO:0040013 negative regulation of locomotion(GO:0040013)
5.0 164.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
4.9 84.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
4.9 14.6 GO:0010643 cell communication by chemical coupling(GO:0010643)
4.9 14.6 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
4.8 9.7 GO:0007386 compartment pattern specification(GO:0007386)
4.8 19.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
4.8 28.7 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
4.8 19.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
4.8 14.3 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
4.8 42.8 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
4.7 61.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
4.7 23.3 GO:0072553 terminal button organization(GO:0072553)
4.7 18.6 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
4.6 18.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
4.6 18.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
4.6 45.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
4.6 13.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
4.5 13.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
4.5 13.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
4.4 93.4 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
4.4 26.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
4.4 26.5 GO:0006021 inositol biosynthetic process(GO:0006021)
4.4 13.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
4.4 13.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
4.3 30.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
4.3 64.4 GO:0000338 protein deneddylation(GO:0000338)
4.3 12.8 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
4.3 21.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
4.2 12.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
4.2 314.5 GO:0045454 cell redox homeostasis(GO:0045454)
4.2 25.4 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
4.2 33.7 GO:0070141 response to UV-A(GO:0070141)
4.2 29.2 GO:0022417 protein maturation by protein folding(GO:0022417)
4.2 12.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
4.2 49.8 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
4.1 41.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
4.1 12.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
4.1 37.2 GO:0006552 leucine catabolic process(GO:0006552)
4.1 20.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
4.1 16.4 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
4.1 32.7 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
4.1 36.5 GO:0006983 ER overload response(GO:0006983)
4.0 724.4 GO:0006364 rRNA processing(GO:0006364)
4.0 20.1 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
4.0 12.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
3.9 11.8 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
3.9 23.5 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
3.9 15.6 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
3.9 34.7 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
3.8 19.1 GO:0002084 protein depalmitoylation(GO:0002084)
3.8 41.5 GO:0032310 prostaglandin secretion(GO:0032310)
3.7 11.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
3.7 15.0 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
3.7 11.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
3.7 3.7 GO:0014806 smooth muscle hyperplasia(GO:0014806)
3.7 11.1 GO:0031507 heterochromatin assembly(GO:0031507)
3.7 11.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
3.7 14.7 GO:0034398 telomere tethering at nuclear periphery(GO:0034398)
3.7 88.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
3.6 14.5 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
3.6 25.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
3.6 243.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
3.6 46.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
3.5 7.0 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
3.5 93.7 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
3.4 75.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
3.4 136.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
3.4 10.2 GO:1901355 response to rapamycin(GO:1901355)
3.4 13.6 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
3.4 13.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
3.4 10.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
3.3 43.0 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
3.3 13.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
3.3 79.0 GO:0007035 vacuolar acidification(GO:0007035)
3.3 19.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
3.3 6.5 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
3.2 13.0 GO:0051013 microtubule severing(GO:0051013)
3.2 34.7 GO:0038092 nodal signaling pathway(GO:0038092)
3.1 18.9 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
3.1 6.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
3.1 6.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
3.1 12.3 GO:0045218 zonula adherens maintenance(GO:0045218)
3.0 3.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
3.0 9.0 GO:0007021 tubulin complex assembly(GO:0007021)
3.0 12.0 GO:0048478 replication fork protection(GO:0048478)
3.0 3.0 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
3.0 3.0 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
3.0 29.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
2.9 32.3 GO:0006265 DNA topological change(GO:0006265)
2.9 11.7 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
2.9 20.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
2.9 17.5 GO:0008298 intracellular mRNA localization(GO:0008298)
2.9 5.8 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.9 8.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.9 37.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.9 2.9 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
2.9 25.8 GO:0051382 kinetochore assembly(GO:0051382)
2.8 5.7 GO:0098502 DNA dephosphorylation(GO:0098502)
2.8 8.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
2.8 11.2 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
2.8 11.2 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
2.8 8.4 GO:0032771 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
2.8 8.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.7 32.6 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
2.6 23.7 GO:0015074 DNA integration(GO:0015074)
2.6 28.7 GO:0009414 response to water deprivation(GO:0009414)
2.6 51.5 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
2.6 10.3 GO:0072683 T cell extravasation(GO:0072683)
2.6 10.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
2.6 2.6 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
2.6 150.7 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
2.5 188.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
2.5 38.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
2.5 22.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
2.5 10.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
2.5 32.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
2.5 7.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
2.5 47.5 GO:0051290 protein heterotetramerization(GO:0051290)
2.5 12.5 GO:0042695 thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
2.5 10.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
2.5 14.8 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
2.4 26.9 GO:0006570 tyrosine metabolic process(GO:0006570)
2.4 9.7 GO:0006551 leucine metabolic process(GO:0006551)
2.4 7.2 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
2.4 7.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
2.4 31.0 GO:0070327 thyroid hormone transport(GO:0070327)
2.4 16.6 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
2.4 82.9 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
2.4 28.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
2.4 58.9 GO:0032508 DNA duplex unwinding(GO:0032508)
2.4 21.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.3 7.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
2.3 91.3 GO:0006270 DNA replication initiation(GO:0006270)
2.3 4.7 GO:0071462 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) cellular response to water stimulus(GO:0071462)
2.3 7.0 GO:0061010 gall bladder development(GO:0061010)
2.3 14.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
2.3 18.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
2.3 9.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
2.3 4.6 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
2.3 13.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
2.3 16.0 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
2.3 18.1 GO:0015939 pantothenate metabolic process(GO:0015939)
2.3 78.9 GO:1901998 toxin transport(GO:1901998)
2.2 71.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
2.2 9.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
2.2 6.7 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
2.2 10.9 GO:0031053 primary miRNA processing(GO:0031053)
2.1 21.5 GO:0045116 protein neddylation(GO:0045116)
2.1 4.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
2.1 17.2 GO:1904753 positive regulation of heart rate by epinephrine(GO:0003065) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
2.1 21.5 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
2.1 14.8 GO:0070836 caveola assembly(GO:0070836)
2.1 12.6 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.1 20.8 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
2.1 16.6 GO:0060155 platelet dense granule organization(GO:0060155)
2.1 6.2 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
2.1 4.1 GO:0034982 mitochondrial protein processing(GO:0034982)
2.1 33.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
2.0 16.4 GO:1900625 monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.0 8.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
2.0 4.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
2.0 3.9 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
2.0 11.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
1.9 15.6 GO:0071763 nuclear membrane organization(GO:0071763)
1.9 15.5 GO:0044351 macropinocytosis(GO:0044351)
1.9 3.9 GO:1902410 mitotic cytokinetic process(GO:1902410)
1.9 3.9 GO:0033591 response to L-ascorbic acid(GO:0033591)
1.9 19.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.9 15.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.9 9.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
1.9 19.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
1.9 37.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.9 17.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
1.9 3.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.9 11.2 GO:0048143 astrocyte activation(GO:0048143)
1.9 7.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
1.9 3.7 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.9 5.6 GO:0048368 lateral mesoderm development(GO:0048368)
1.9 1.9 GO:1902908 regulation of melanosome transport(GO:1902908)
1.9 18.5 GO:0001895 retina homeostasis(GO:0001895)
1.8 5.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.8 9.2 GO:0006041 glucosamine metabolic process(GO:0006041)
1.8 23.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
1.8 12.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
1.8 5.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.8 38.5 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
1.8 20.0 GO:0051451 myoblast migration(GO:0051451)
1.8 16.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
1.8 9.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
1.8 8.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
1.8 10.6 GO:0032328 alanine transport(GO:0032328)
1.8 3.5 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
1.7 15.7 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
1.7 13.9 GO:0006689 ganglioside catabolic process(GO:0006689)
1.7 3.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
1.7 5.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
1.7 12.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
1.7 6.8 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.7 1.7 GO:1990791 dorsal root ganglion development(GO:1990791)
1.7 5.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.7 8.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.6 4.9 GO:0051684 maintenance of Golgi location(GO:0051684)
1.6 23.0 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
1.6 22.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.6 9.6 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
1.6 17.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.6 12.8 GO:0043457 regulation of cellular respiration(GO:0043457)
1.6 46.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.6 3.2 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
1.6 3.2 GO:0071888 macrophage apoptotic process(GO:0071888)
1.6 23.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.6 7.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
1.6 1.6 GO:0040031 snRNA modification(GO:0040031)
1.6 18.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
1.5 9.3 GO:0010659 cardiac muscle cell apoptotic process(GO:0010659)
1.5 4.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.5 4.6 GO:2000489 regulation of hepatic stellate cell activation(GO:2000489) positive