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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for MYB

Z-value: 3.59

Motif logo

Transcription factors associated with MYB

Gene Symbol Gene ID Gene Info
ENSG00000118513.14 MYB proto-oncogene, transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYBhg19_v2_chr6_+_135502408_1355024590.261.4e-04Click!

Activity profile of MYB motif

Sorted Z-values of MYB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_54863739 101.07 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chr14_+_54863667 92.53 ENST00000335183.6
cyclin-dependent kinase inhibitor 3
chr14_+_54863682 90.58 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
cyclin-dependent kinase inhibitor 3
chr19_-_14530143 72.71 ENST00000242776.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr19_+_49497121 70.79 ENST00000413176.2
RuvB-like AAA ATPase 2
chr3_+_52444651 70.41 ENST00000327906.3
PHD finger protein 7
chr17_+_7155556 69.41 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
elongator acetyltransferase complex subunit 5
chr1_+_43824669 59.92 ENST00000372462.1
cell division cycle 20
chr17_+_7155819 59.44 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr1_+_43824577 59.33 ENST00000310955.6
cell division cycle 20
chr11_+_34073872 58.49 ENST00000530820.1
cell cycle associated protein 1
chr17_+_7155343 57.86 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
elongator acetyltransferase complex subunit 5
chr11_+_34073269 57.07 ENST00000389645.3
cell cycle associated protein 1
chr6_+_167412835 54.93 ENST00000349556.4
FGFR1 oncogene partner
chr2_-_27632390 51.08 ENST00000350803.4
ENST00000344034.4
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr13_-_103426112 50.32 ENST00000376032.4
ENST00000376029.3
testis expressed 30
chr13_-_103426081 49.23 ENST00000376022.1
ENST00000376021.4
testis expressed 30
chr9_+_131219179 48.60 ENST00000372791.3
outer dense fiber of sperm tails 2
chr1_-_153643442 48.42 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr17_+_33914460 47.83 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr17_-_73781567 47.80 ENST00000586607.1
H3 histone, family 3B (H3.3B)
chr19_+_49496705 47.33 ENST00000595090.1
RuvB-like AAA ATPase 2
chr12_-_10875831 46.99 ENST00000279550.7
ENST00000228251.4
Y box binding protein 3
chr11_+_34073757 46.80 ENST00000532820.1
cell cycle associated protein 1
chr17_+_33914276 46.24 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr11_+_18433840 44.50 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr17_-_33288467 43.67 ENST00000436961.3
chaperonin containing TCP1, subunit 6B (zeta 2)
chr17_-_33288522 43.31 ENST00000314144.5
chaperonin containing TCP1, subunit 6B (zeta 2)
chr8_-_101734907 40.06 ENST00000318607.5
ENST00000521865.1
ENST00000520804.1
ENST00000522720.1
ENST00000521067.1
poly(A) binding protein, cytoplasmic 1
chr11_+_34073195 40.01 ENST00000341394.4
cell cycle associated protein 1
chr19_+_49496782 39.32 ENST00000601968.1
ENST00000596837.1
RuvB-like AAA ATPase 2
chr1_+_154947148 38.87 ENST00000368436.1
ENST00000308987.5
CDC28 protein kinase regulatory subunit 1B
chr7_-_72993033 38.13 ENST00000305632.5
transducin (beta)-like 2
chr1_+_165796753 38.09 ENST00000367879.4
uridine-cytidine kinase 2
chr19_+_1104415 37.93 ENST00000585362.2
glutathione peroxidase 4
chr17_-_33288419 37.57 ENST00000421975.3
chaperonin containing TCP1, subunit 6B (zeta 2)
chr1_+_154947126 37.00 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chr12_-_57081940 36.94 ENST00000436399.2
prostaglandin E synthase 3 (cytosolic)
chrX_+_23682379 36.90 ENST00000379349.1
peroxiredoxin 4
chr10_-_43904608 36.61 ENST00000337970.3
heterogeneous nuclear ribonucleoprotein F
chr3_+_49058444 36.18 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr10_-_43904235 35.63 ENST00000356053.3
heterogeneous nuclear ribonucleoprotein F
chr1_-_211848899 35.34 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NIMA-related kinase 2
chr1_-_85155939 35.23 ENST00000603677.1
synovial sarcoma, X breakpoint 2 interacting protein
chr3_+_49059038 33.95 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr11_-_47664072 33.76 ENST00000542981.1
ENST00000530428.1
ENST00000302503.3
mitochondrial carrier 2
chr4_-_100871506 32.42 ENST00000296417.5
H2A histone family, member Z
chr17_-_80231300 31.67 ENST00000398519.5
ENST00000580446.1
casein kinase 1, delta
chrX_-_129299847 31.29 ENST00000319908.3
ENST00000287295.3
apoptosis-inducing factor, mitochondrion-associated, 1
chrX_-_129299638 31.09 ENST00000535724.1
ENST00000346424.2
apoptosis-inducing factor, mitochondrion-associated, 1
chr19_+_47104553 30.96 ENST00000598871.1
ENST00000594523.1
calmodulin 3 (phosphorylase kinase, delta)
chr17_+_7210898 30.82 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr19_+_47634039 30.80 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr16_-_58163299 30.71 ENST00000262498.3
chromosome 16 open reading frame 80
chr6_+_22569784 30.62 ENST00000510882.2
hepatoma derived growth factor-like 1
chr12_-_31479045 30.23 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr5_+_151151471 30.23 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr8_-_101734170 29.68 ENST00000522387.1
ENST00000518196.1
poly(A) binding protein, cytoplasmic 1
chr9_+_140135665 29.31 ENST00000340384.4
tubulin, beta 4B class IVb
chr19_+_59055814 28.84 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
tripartite motif containing 28
chr3_+_49057876 28.04 ENST00000326912.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr7_-_65447192 27.45 ENST00000421103.1
ENST00000345660.6
ENST00000304895.4
glucuronidase, beta
chr6_-_149969829 27.41 ENST00000367411.2
katanin p60 (ATPase containing) subunit A 1
chr4_-_1713977 27.31 ENST00000318386.4
stem-loop binding protein
chr3_-_186857267 27.09 ENST00000455270.1
ENST00000296277.4
ribosomal protein L39-like
chr5_-_68665815 27.09 ENST00000380818.3
ENST00000328663.4
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr19_-_55919087 27.04 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr14_+_24458093 26.79 ENST00000558753.1
ENST00000537912.1
dehydrogenase/reductase (SDR family) member 4 like 2
chr8_-_67976509 26.66 ENST00000518747.1
COP9 signalosome subunit 5
chr20_+_35807449 26.33 ENST00000237530.6
ribophorin II
chr3_+_160117087 26.21 ENST00000357388.3
structural maintenance of chromosomes 4
chr4_-_1714037 26.10 ENST00000488267.1
ENST00000429429.2
ENST00000480936.1
stem-loop binding protein
chr8_-_101734308 25.81 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
poly(A) binding protein, cytoplasmic 1
chr3_-_141747439 25.52 ENST00000467667.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr17_+_30677136 25.12 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
zinc finger protein 207
chr8_-_71519889 24.93 ENST00000521425.1
translocation associated membrane protein 1
chr12_-_66563786 24.92 ENST00000542724.1
transmembrane BAX inhibitor motif containing 4
chr1_+_52195480 24.51 ENST00000531828.1
ENST00000361556.5
ENST00000481937.1
oxysterol binding protein-like 9
chr5_+_151151504 24.43 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr17_-_4852332 24.31 ENST00000572383.1
profilin 1
chr6_+_34204642 24.24 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr8_-_71520513 24.04 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
translocation associated membrane protein 1
chr1_+_155658849 23.98 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
death associated protein 3
chr3_+_160117418 23.95 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
structural maintenance of chromosomes 4
chr2_-_38978492 23.89 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
serine/arginine-rich splicing factor 7
chr20_+_35807512 23.87 ENST00000373622.5
ribophorin II
chr2_+_39005325 23.77 ENST00000281950.3
gem (nuclear organelle) associated protein 6
chr2_+_39005336 23.63 ENST00000409566.1
gem (nuclear organelle) associated protein 6
chr13_+_28194873 23.62 ENST00000302979.3
polymerase (RNA) I polypeptide D, 16kDa
chr7_-_105752651 23.57 ENST00000470347.1
ENST00000455385.2
synaptophysin-like 1
chr2_-_128784846 23.56 ENST00000259235.3
ENST00000357702.5
ENST00000424298.1
Sin3A-associated protein, 130kDa
chr1_+_93544821 23.25 ENST00000370303.4
metal response element binding transcription factor 2
chr6_-_36515177 23.22 ENST00000229812.7
serine/threonine kinase 38
chr1_+_155178481 23.19 ENST00000368376.3
metaxin 1
chr14_-_23451467 23.06 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chr2_-_69614373 23.01 ENST00000361060.5
ENST00000357308.4
glutamine--fructose-6-phosphate transaminase 1
chr12_+_110906169 22.36 ENST00000377673.5
family with sequence similarity 216, member A
chr1_-_155658766 22.14 ENST00000295566.4
ENST00000368330.2
YY1 associated protein 1
chr1_-_38061522 21.59 ENST00000373062.3
guanine nucleotide binding protein-like 2 (nucleolar)
chr6_+_34725263 21.47 ENST00000374018.1
ENST00000374017.3
small nuclear ribonucleoprotein polypeptide C
chr11_-_67888881 21.42 ENST00000356135.5
choline kinase alpha
chr3_+_52740094 21.31 ENST00000602728.1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr22_-_19466683 21.28 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
ubiquitin fusion degradation 1 like (yeast)
chr13_+_25670268 21.18 ENST00000281589.3
poly(A) binding protein, cytoplasmic 3
chr3_-_182698381 20.68 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr1_+_43148059 20.59 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr2_-_9771075 20.58 ENST00000446619.1
ENST00000238081.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr16_+_88923494 20.46 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
trafficking protein particle complex 2-like
chr22_-_19466732 20.46 ENST00000263202.10
ENST00000360834.4
ubiquitin fusion degradation 1 like (yeast)
chr8_-_101964231 20.41 ENST00000521309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr14_+_89029366 20.30 ENST00000555799.1
ENST00000555755.1
ENST00000393514.5
zinc finger CCCH-type containing 14
chr17_-_7197881 20.29 ENST00000007699.5
Y box binding protein 2
chr7_-_148581360 20.26 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr17_-_4852243 19.94 ENST00000225655.5
profilin 1
chr6_-_41040195 19.88 ENST00000463088.1
ENST00000469104.1
ENST00000486443.1
O-acyl-ADP-ribose deacylase 1
chr1_-_155658260 19.81 ENST00000368339.5
ENST00000405763.3
ENST00000368340.5
ENST00000454523.1
ENST00000443231.1
ENST00000347088.5
ENST00000361831.5
ENST00000355499.4
YY1 associated protein 1
chr2_-_111435610 19.69 ENST00000447014.1
ENST00000420328.1
ENST00000535254.1
ENST00000409311.1
ENST00000302759.6
BUB1 mitotic checkpoint serine/threonine kinase
chr12_+_120933904 19.58 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
dynein, light chain, LC8-type 1
chr1_-_159893507 19.56 ENST00000368096.1
transgelin 2
chr1_-_156308018 19.46 ENST00000496684.2
ENST00000368259.2
ENST00000368261.3
ENST00000472765.2
ENST00000533194.1
ENST00000478640.2
chaperonin containing TCP1, subunit 3 (gamma)
chr18_-_34408693 19.36 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
tubulin polyglutamylase complex subunit 2
chr2_-_10978103 19.27 ENST00000404824.2
protein disulfide isomerase family A, member 6
chr19_+_17416609 19.25 ENST00000602206.1
mitochondrial ribosomal protein L34
chr1_+_52195542 19.23 ENST00000462759.1
ENST00000486942.1
oxysterol binding protein-like 9
chr15_-_78592053 19.03 ENST00000267973.2
WD repeat domain 61
chr1_+_155178518 19.02 ENST00000316721.4
metaxin 1
chr18_-_34409116 18.97 ENST00000334295.4
tubulin polyglutamylase complex subunit 2
chr21_-_46237883 18.88 ENST00000397893.3
small ubiquitin-like modifier 3
chr19_-_10305752 18.80 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNA (cytosine-5-)-methyltransferase 1
chr13_+_28195988 18.76 ENST00000399697.3
ENST00000399696.1
polymerase (RNA) I polypeptide D, 16kDa
chr2_+_242289502 18.70 ENST00000451310.1
septin 2
chr1_-_68962805 18.68 ENST00000370966.5
DEP domain containing 1
chr19_-_50432782 18.51 ENST00000413454.1
ENST00000596437.1
ENST00000341114.3
ENST00000595948.1
nucleoporin 62kDa
interleukin 4 induced 1
chr1_-_155658518 18.48 ENST00000404643.1
ENST00000359205.5
ENST00000407221.1
YY1 associated protein 1
chr14_+_89029336 18.47 ENST00000556945.1
ENST00000556158.1
ENST00000557607.1
zinc finger CCCH-type containing 14
chr18_+_3449821 18.43 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr19_-_8070474 18.43 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1
chr3_-_88108192 18.36 ENST00000309534.6
CGG triplet repeat binding protein 1
chr4_-_57687847 18.08 ENST00000504762.1
ENST00000248701.4
ENST00000506738.1
serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
chr8_-_21999362 17.93 ENST00000334530.5
ENST00000518664.1
receptor accessory protein 4
chr19_+_1104048 17.90 ENST00000593032.1
ENST00000588919.1
glutathione peroxidase 4
chr18_+_19192228 17.55 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr21_+_44394742 17.54 ENST00000432907.2
PBX/knotted 1 homeobox 1
chr11_-_67888671 17.53 ENST00000265689.4
choline kinase alpha
chr13_+_21714913 17.51 ENST00000450573.1
ENST00000467636.1
Sin3A-associated protein, 18kDa
chr18_-_34408902 17.51 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
tubulin polyglutamylase complex subunit 2
chr6_-_149969871 17.41 ENST00000335643.8
ENST00000444282.1
katanin p60 (ATPase containing) subunit A 1
chr19_+_17413663 17.37 ENST00000594999.1
mitochondrial ribosomal protein L34
chr2_+_48010221 17.18 ENST00000234420.5
mutS homolog 6
chr22_-_22090064 17.13 ENST00000339468.3
yippee-like 1 (Drosophila)
chr18_+_12703002 17.08 ENST00000590217.1
proteasome (prosome, macropain) assembly chaperone 2
chr9_+_33025209 16.98 ENST00000330899.4
ENST00000544625.1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_+_38158090 16.75 ENST00000373055.1
ENST00000327331.2
cell division cycle associated 8
chr14_+_23791159 16.65 ENST00000557702.1
poly(A) binding protein, nuclear 1
chr2_-_174828892 16.63 ENST00000418194.2
Sp3 transcription factor
chr2_+_61244697 16.51 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
peroxisomal biogenesis factor 13
chr8_-_101964265 16.47 ENST00000395958.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_-_155658085 16.46 ENST00000311573.5
ENST00000438245.2
YY1 associated protein 1
chr1_+_212208919 16.41 ENST00000366991.4
ENST00000542077.1
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr18_+_3449695 16.38 ENST00000343820.5
TGFB-induced factor homeobox 1
chr15_-_78591912 16.32 ENST00000560569.1
ENST00000558459.1
ENST00000558311.1
WD repeat domain 61
chr19_+_36195467 16.26 ENST00000426659.2
zinc finger and BTB domain containing 32
chr15_+_79165372 16.16 ENST00000558502.1
mortality factor 4 like 1
chr8_-_21999447 16.14 ENST00000306306.3
ENST00000521744.1
receptor accessory protein 4
chr16_+_67063036 16.13 ENST00000290858.6
ENST00000564034.1
core-binding factor, beta subunit
chr2_-_153574480 16.06 ENST00000410080.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr10_-_13390021 16.04 ENST00000537130.1
selenophosphate synthetase 1
chr12_+_120933859 15.96 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
dynein, light chain, LC8-type 1
chr1_+_11072696 15.93 ENST00000240185.3
ENST00000476201.1
TAR DNA binding protein
chr20_-_54967187 15.91 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
aurora kinase A
chr2_-_203776864 15.91 ENST00000261015.4
WD repeat domain 12
chr8_+_17780346 15.87 ENST00000325083.8
pericentriolar material 1
chr8_+_91013676 15.84 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
2,4-dienoyl CoA reductase 1, mitochondrial
chr1_-_33502528 15.79 ENST00000354858.6
adenylate kinase 2
chr12_+_121124921 15.78 ENST00000412616.2
malectin
chr1_-_159894319 15.77 ENST00000320307.4
transgelin 2
chr7_+_157130214 15.72 ENST00000412557.1
ENST00000453383.1
DnaJ (Hsp40) homolog, subfamily B, member 6
chr3_-_113465065 15.56 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_+_32479430 15.38 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chr6_-_41040268 15.37 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
O-acyl-ADP-ribose deacylase 1
chr14_+_96968802 15.35 ENST00000556619.1
ENST00000392990.2
poly(A) polymerase alpha
chr8_+_91013577 15.31 ENST00000220764.2
2,4-dienoyl CoA reductase 1, mitochondrial
chr4_+_128703295 15.30 ENST00000296464.4
ENST00000508549.1
heat shock 70kDa protein 4-like
chr5_+_61602055 15.28 ENST00000381103.2
kinesin heavy chain member 2A
chr12_+_66217911 15.26 ENST00000403681.2
high mobility group AT-hook 2
chr8_-_102217515 15.22 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
zinc finger protein 706
chr16_+_66586461 15.19 ENST00000264001.4
ENST00000351137.4
ENST00000345436.4
ENST00000362093.4
ENST00000417030.2
ENST00000527729.1
ENST00000532838.1
chemokine-like factor
CKLF-CMTM1 readthrough
chr9_+_100745615 15.07 ENST00000339399.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr5_-_43557791 15.02 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr4_+_128702969 15.01 ENST00000508776.1
ENST00000439123.2
heat shock 70kDa protein 4-like
chrX_-_153285251 14.84 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr19_+_1407517 14.83 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr8_-_124408652 14.75 ENST00000287394.5
ATPase family, AAA domain containing 2
chr17_-_79895097 14.64 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
pyrroline-5-carboxylate reductase 1
chr1_-_167905225 14.56 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr20_-_43589109 14.43 ENST00000372813.3
translocase of outer mitochondrial membrane 34
chr12_-_6961050 14.35 ENST00000538862.2
cell division cycle associated 3
chr1_+_145883868 14.30 ENST00000447947.2
G protein-coupled receptor 89C
chr12_+_122242597 14.24 ENST00000267197.5
SET domain containing 1B
chr17_+_4699439 14.12 ENST00000270586.3
proteasome (prosome, macropain) subunit, beta type, 6

Network of associatons between targets according to the STRING database.

First level regulatory network of MYB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
39.4 157.4 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
14.4 28.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
12.5 62.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
11.8 59.0 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
11.8 35.3 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
11.5 11.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
10.6 95.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
9.5 38.1 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
9.0 26.9 GO:0006172 ADP biosynthetic process(GO:0006172)
8.9 62.4 GO:1904044 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
8.8 70.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
8.2 24.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
8.2 106.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
8.0 32.1 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
7.5 44.8 GO:0051013 microtubule severing(GO:0051013)
7.4 44.5 GO:0019249 lactate biosynthetic process(GO:0019249)
7.4 36.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
7.3 22.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
7.3 210.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
6.9 20.8 GO:0006404 RNA import into nucleus(GO:0006404)
6.8 20.3 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
6.7 6.7 GO:0060623 regulation of chromosome condensation(GO:0060623)
6.3 44.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
5.9 47.0 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
5.8 34.9 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
5.7 22.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
5.5 16.6 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
5.5 16.5 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
5.3 15.9 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
5.1 20.3 GO:0009386 translational attenuation(GO:0009386)
5.0 35.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
5.0 69.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
4.9 19.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
4.9 19.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
4.8 48.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
4.7 18.8 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
4.6 27.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
4.5 40.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
4.5 22.7 GO:0035617 stress granule disassembly(GO:0035617)
4.4 44.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
4.4 13.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
4.0 32.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
4.0 7.9 GO:0044211 CTP salvage(GO:0044211)
3.9 39.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
3.9 3.9 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
3.9 39.0 GO:0019695 choline metabolic process(GO:0019695)
3.9 15.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
3.9 7.7 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
3.8 15.4 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
3.6 10.9 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) L-kynurenine metabolic process(GO:0097052)
3.6 124.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
3.4 47.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
3.4 13.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
3.3 23.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
3.3 52.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
3.2 13.0 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
3.2 35.5 GO:0035721 intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
3.1 12.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
3.1 3.1 GO:0043244 regulation of translational termination(GO:0006449) regulation of protein complex disassembly(GO:0043244)
3.1 9.3 GO:0018158 protein oxidation(GO:0018158)
3.0 39.6 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.9 49.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
2.9 335.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
2.9 63.7 GO:0019372 lipoxygenase pathway(GO:0019372)
2.9 8.6 GO:1900063 regulation of peroxisome organization(GO:1900063)
2.8 22.3 GO:0015866 ADP transport(GO:0015866)
2.7 27.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
2.7 16.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
2.7 10.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
2.6 65.9 GO:0034453 microtubule anchoring(GO:0034453)
2.6 39.0 GO:0090168 Golgi reassembly(GO:0090168)
2.6 12.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.5 7.5 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
2.4 14.5 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
2.4 9.7 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
2.4 9.5 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
2.3 157.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
2.3 9.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
2.3 18.1 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
2.2 11.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
2.2 15.5 GO:0006642 triglyceride mobilization(GO:0006642)
2.2 8.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.1 88.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.1 17.0 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
2.1 8.3 GO:0002326 B cell lineage commitment(GO:0002326)
2.0 8.2 GO:0097167 circadian regulation of translation(GO:0097167)
2.0 11.9 GO:0007296 vitellogenesis(GO:0007296)
1.9 19.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
1.9 3.9 GO:0001923 B-1 B cell differentiation(GO:0001923)
1.9 7.7 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
1.9 7.7 GO:0030242 pexophagy(GO:0030242)
1.8 12.7 GO:0001675 acrosome assembly(GO:0001675)
1.8 19.8 GO:0033182 regulation of histone ubiquitination(GO:0033182)
1.8 3.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.8 3.5 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.7 21.8 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
1.7 13.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.6 14.7 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.6 23.9 GO:0045116 protein neddylation(GO:0045116)
1.6 26.9 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
1.5 60.3 GO:0048255 mRNA stabilization(GO:0048255)
1.5 30.8 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
1.5 7.6 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
1.5 27.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
1.5 42.2 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
1.4 4.3 GO:2000397 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
1.4 49.2 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
1.4 7.2 GO:0071233 cellular response to leucine(GO:0071233)
1.4 26.7 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
1.4 5.6 GO:0060480 lung goblet cell differentiation(GO:0060480)
1.4 13.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.4 4.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
1.4 20.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.4 12.4 GO:0046085 adenosine metabolic process(GO:0046085)
1.4 13.7 GO:0035092 sperm chromatin condensation(GO:0035092)
1.4 32.7 GO:0043968 histone H2A acetylation(GO:0043968)
1.4 12.2 GO:0006089 lactate metabolic process(GO:0006089)
1.4 101.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.3 57.9 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.3 8.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.3 15.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.3 5.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.3 10.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
1.2 7.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.2 19.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
1.2 7.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.2 8.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.2 1.2 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
1.1 3.4 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
1.1 10.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.1 7.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.1 5.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
1.1 3.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
1.1 43.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
1.1 42.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
1.0 1.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
1.0 18.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
1.0 3.9 GO:1904526 regulation of microtubule binding(GO:1904526)
1.0 60.0 GO:0032392 DNA geometric change(GO:0032392)
1.0 3.9 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.0 21.3 GO:0006465 signal peptide processing(GO:0006465)
1.0 28.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
1.0 2.9 GO:1902534 single-organism membrane invagination(GO:1902534)
1.0 10.5 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
1.0 3.8 GO:0072302 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.9 4.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.9 5.6 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.9 4.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.9 1.8 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.9 5.4 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.9 15.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.9 2.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.9 75.7 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.8 16.0 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.8 1.7 GO:1901661 quinone metabolic process(GO:1901661)
0.8 4.9 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.8 5.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.8 10.0 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.8 9.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.7 6.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.7 116.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.7 43.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.7 39.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.7 5.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.7 15.0 GO:0021591 ventricular system development(GO:0021591)
0.7 2.8 GO:1904753 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.7 20.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.7 3.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.7 3.4 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.7 13.7 GO:0032060 bleb assembly(GO:0032060)
0.7 10.5 GO:0006853 carnitine shuttle(GO:0006853)
0.7 48.4 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.6 6.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.6 3.2 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.6 7.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.6 27.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.6 6.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.6 2.5 GO:0002254 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.6 2.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 29.7 GO:0006342 chromatin silencing(GO:0006342)
0.6 6.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.6 5.6 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.6 3.9 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.6 18.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.5 2.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.5 23.6 GO:0046464 neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.5 12.2 GO:0034389 lipid particle organization(GO:0034389)
0.5 3.6 GO:0048318 axial mesoderm development(GO:0048318)
0.5 6.7 GO:0045008 depyrimidination(GO:0045008)
0.5 4.6 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.5 4.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.5 5.5 GO:0070986 left/right axis specification(GO:0070986)
0.5 1.5 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.5 6.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.5 5.8 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.5 6.8 GO:1903540 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) protein localization to postsynaptic membrane(GO:1903539) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.5 5.3 GO:2000849 glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849)
0.5 8.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.5 4.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.5 3.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.5 9.1 GO:0016180 snRNA processing(GO:0016180)
0.4 65.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.4 2.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.4 29.2 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.4 4.0 GO:0015889 cobalamin transport(GO:0015889)
0.4 1.6 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.4 7.5 GO:0000732 strand displacement(GO:0000732)
0.4 1.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.4 12.4 GO:0035036 sperm-egg recognition(GO:0035036)
0.4 5.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.4 1.4 GO:0021564 vagus nerve development(GO:0021564)
0.4 5.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.3 8.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 11.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 15.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.3 5.4 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.3 2.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.3 23.2 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.3 0.7 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.3 2.9 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.3 6.6 GO:0002643 regulation of tolerance induction(GO:0002643)
0.3 5.4 GO:0007172 signal complex assembly(GO:0007172)
0.3 1.5 GO:0048017 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.3 15.1 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.3 6.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.3 5.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3 9.1 GO:0000266 mitochondrial fission(GO:0000266)
0.3 6.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.3 7.7 GO:0032288 myelin assembly(GO:0032288)
0.3 1.9 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.3 3.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 10.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.3 6.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 4.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 2.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 4.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 1.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.2 3.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 3.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 1.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.2 12.8 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.2 2.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.2 1.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 7.8 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.2 3.0 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2 1.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.2 1.7 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.2 12.1 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 5.8 GO:0060416 response to growth hormone(GO:0060416)
0.2 0.3 GO:0051705 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) multi-organism behavior(GO:0051705)
0.2 11.2 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.1 9.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 14.1 GO:0051289 protein homotetramerization(GO:0051289)
0.1 12.3 GO:0007286 spermatid development(GO:0007286)
0.1 2.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 5.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.8 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 5.6 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.7 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 5.9 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 21.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 3.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 12.4 GO:0002576 platelet degranulation(GO:0002576)
0.1 2.6 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.0 GO:0015871 choline transport(GO:0015871)
0.1 38.6 GO:0030335 positive regulation of cell migration(GO:0030335)
0.1 1.4 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 8.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 2.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.9 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 4.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.3 GO:1901976 regulation of cell cycle checkpoint(GO:1901976) regulation of DNA damage checkpoint(GO:2000001)
0.1 4.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 2.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 20.6 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 8.4 GO:0006413 translational initiation(GO:0006413)
0.1 6.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 3.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.2 GO:0000305 response to oxygen radical(GO:0000305)
0.1 4.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.5 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 4.6 GO:0006457 protein folding(GO:0006457)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
20.7 186.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
15.7 157.4 GO:0097255 R2TP complex(GO:0097255)
9.3 74.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
8.8 35.3 GO:0055087 Ski complex(GO:0055087)
7.7 30.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
7.6 144.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
7.5 30.2 GO:0032301 MutSalpha complex(GO:0032301)
7.0 70.3 GO:0000796 condensin complex(GO:0000796)
6.9 48.6 GO:0001520 outer dense fiber(GO:0001520)
6.6 19.8 GO:0031372 UBC13-MMS2 complex(GO:0031372)
6.5 39.1 GO:0001740 Barr body(GO:0001740)
6.0 29.9 GO:0035061 interchromatin granule(GO:0035061)
5.9 47.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
5.4 347.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
5.2 156.9 GO:0005680 anaphase-promoting complex(GO:0005680)
5.2 62.7 GO:0005642 annulate lamellae(GO:0005642)
5.2 82.7 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
5.0 94.1 GO:0036020 endolysosome membrane(GO:0036020)
4.7 37.2 GO:0032133 chromosome passenger complex(GO:0032133)
4.5 27.1 GO:0070761 pre-snoRNP complex(GO:0070761)
4.4 13.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
4.3 26.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
4.3 13.0 GO:0005588 collagen type V trimer(GO:0005588)
4.2 50.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
4.0 51.4 GO:0000243 commitment complex(GO:0000243)
3.3 39.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
3.3 19.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
3.3 19.7 GO:0071817 MMXD complex(GO:0071817)
3.2 42.0 GO:0097227 sperm annulus(GO:0097227)
3.1 9.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
3.0 21.3 GO:0005787 signal peptidase complex(GO:0005787)
3.0 57.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
2.9 14.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
2.8 74.8 GO:0070822 Sin3-type complex(GO:0070822)
2.7 15.9 GO:0070545 PeBoW complex(GO:0070545)
2.6 10.5 GO:0071001 U4/U6 snRNP(GO:0071001)
2.6 7.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
2.4 42.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
2.2 15.6 GO:0031415 NatA complex(GO:0031415)
2.1 48.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
2.1 22.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
2.1 16.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.0 30.2 GO:0000346 transcription export complex(GO:0000346)
2.0 55.2 GO:0034451 centriolar satellite(GO:0034451)
1.8 7.0 GO:0005846 nuclear cap binding complex(GO:0005846)
1.7 5.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.7 20.5 GO:0030008 TRAPP complex(GO:0030008)
1.7 26.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.6 6.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.6 12.6 GO:0042382 paraspeckles(GO:0042382)
1.6 6.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
1.5 6.0 GO:1990423 RZZ complex(GO:1990423)
1.5 80.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.4 12.7 GO:0031105 septin complex(GO:0031105)
1.4 5.6 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.4 23.6 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.3 7.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.2 20.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
1.2 3.5 GO:0005879 axonemal microtubule(GO:0005879)
1.1 33.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
1.1 14.3 GO:0097524 sperm plasma membrane(GO:0097524)
1.0 9.1 GO:0032039 integrator complex(GO:0032039)
1.0 19.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.0 8.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.0 10.6 GO:0034709 methylosome(GO:0034709)
1.0 7.7 GO:0032389 MutLalpha complex(GO:0032389)
1.0 15.3 GO:0005682 U5 snRNP(GO:0005682)
1.0 8.6 GO:0005638 lamin filament(GO:0005638)
0.9 36.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.9 16.1 GO:0071004 U2-type prespliceosome(GO:0071004)
0.9 88.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.9 9.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.9 24.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.9 45.8 GO:0005844 polysome(GO:0005844)
0.9 4.4 GO:0033503 HULC complex(GO:0033503)
0.9 1.7 GO:0072687 meiotic spindle(GO:0072687)
0.8 10.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.8 45.0 GO:0005876 spindle microtubule(GO:0005876)
0.8 66.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.8 103.8 GO:0000922 spindle pole(GO:0000922)
0.8 22.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.8 7.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.8 12.4 GO:0097346 INO80-type complex(GO:0097346)
0.8 3.9 GO:0032449 CBM complex(GO:0032449)
0.7 24.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.7 4.1 GO:1990635 proximal dendrite(GO:1990635)
0.7 2.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.6 24.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.6 16.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6 4.3 GO:0000813 ESCRT I complex(GO:0000813)
0.6 3.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.6 8.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.6 50.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.6 12.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 7.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.5 2.2 GO:0005801 cis-Golgi network(GO:0005801)
0.5 4.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.5 42.9 GO:0035580 specific granule lumen(GO:0035580)
0.5 20.0 GO:0097546 ciliary base(GO:0097546)
0.5 5.1 GO:0097223 sperm part(GO:0097223)
0.5 177.6 GO:0016607 nuclear speck(GO:0016607)
0.5 3.4 GO:0005652 nuclear lamina(GO:0005652)
0.5 3.8 GO:0000242 pericentriolar material(GO:0000242)
0.5 46.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 9.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 5.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 5.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4 39.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.4 4.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.4 8.5 GO:0071564 npBAF complex(GO:0071564)
0.4 3.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.4 41.3 GO:0031902 late endosome membrane(GO:0031902)
0.4 6.4 GO:0030904 retromer complex(GO:0030904)
0.3 8.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.3 28.1 GO:0031514 motile cilium(GO:0031514)
0.3 4.1 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.3 1.2 GO:0035838 growing cell tip(GO:0035838)
0.3 9.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 7.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 8.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 20.4 GO:0031672 A band(GO:0031672)
0.3 0.8 GO:0097361 CIA complex(GO:0097361)
0.3 35.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 28.9 GO:0016605 PML body(GO:0016605)
0.3 2.8 GO:0097225 sperm midpiece(GO:0097225)
0.3 2.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 14.1 GO:0000502 proteasome complex(GO:0000502)
0.2 5.4 GO:0000421 autophagosome membrane(GO:0000421)
0.2 3.5 GO:0005875 microtubule associated complex(GO:0005875)
0.2 42.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 77.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 10.7 GO:0036064 ciliary basal body(GO:0036064)
0.2 5.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 16.5 GO:0005643 nuclear pore(GO:0005643)
0.2 6.8 GO:0009925 basal plasma membrane(GO:0009925)
0.2 2.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 29.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.2 11.5 GO:0016363 nuclear matrix(GO:0016363)
0.2 13.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.5 GO:0045178 basal part of cell(GO:0045178)
0.1 11.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.4 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 5.0 GO:0005811 lipid particle(GO:0005811)
0.1 6.9 GO:0005795 Golgi stack(GO:0005795)
0.1 86.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 3.5 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 47.3 GO:0005925 focal adhesion(GO:0005925)
0.1 11.2 GO:0035579 specific granule membrane(GO:0035579)
0.1 4.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.3 GO:0005912 adherens junction(GO:0005912)
0.1 3.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 3.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 4.9 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 4.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.2 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
26.2 157.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
19.9 119.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
15.9 63.7 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
15.1 60.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
13.0 39.0 GO:0004103 choline kinase activity(GO:0004103)
12.2 48.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
11.3 33.8 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
10.8 75.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
10.7 53.4 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
8.6 60.3 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
7.8 31.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
7.5 30.2 GO:0032143 single thymine insertion binding(GO:0032143)
7.5 44.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
7.3 22.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
7.1 121.5 GO:0008494 translation activator activity(GO:0008494)
6.9 27.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
6.8 27.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
6.6 46.0 GO:0004849 uridine kinase activity(GO:0004849)
6.3 282.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
5.1 30.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
5.0 50.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
5.0 19.8 GO:0032038 myosin II heavy chain binding(GO:0032038)
4.6 36.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
4.3 159.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
4.3 94.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
4.2 62.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
4.1 20.7 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
4.1 12.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
3.9 7.7 GO:0030983 mismatched DNA binding(GO:0030983)
3.8 26.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
3.7 44.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.6 10.9 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
3.6 28.8 GO:0070087 chromo shadow domain binding(GO:0070087)
3.2 80.1 GO:0008143 poly(A) binding(GO:0008143)
3.1 18.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
3.1 30.6 GO:0051425 PTB domain binding(GO:0051425)
2.9 17.6 GO:1990446 U1 snRNP binding(GO:1990446)
2.9 11.5 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
2.8 11.2 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
2.7 8.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
2.7 10.8 GO:0005347 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
2.7 93.5 GO:0001671 ATPase activator activity(GO:0001671)
2.7 26.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
2.7 10.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
2.6 7.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
2.6 18.0 GO:0050733 RS domain binding(GO:0050733)
2.6 30.8 GO:0031386 protein tag(GO:0031386)
2.4 4.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
2.4 42.6 GO:0017070 U6 snRNA binding(GO:0017070)
2.4 42.4 GO:0001054 RNA polymerase I activity(GO:0001054)
2.3 9.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.3 41.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
2.3 20.5 GO:0035174 histone serine kinase activity(GO:0035174)
2.3 20.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
2.2 26.9 GO:0004017 adenylate kinase activity(GO:0004017)
2.1 10.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.9 7.7 GO:0031208 POZ domain binding(GO:0031208)
1.9 5.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.8 12.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.8 14.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.8 23.1 GO:0045294 alpha-catenin binding(GO:0045294)
1.7 24.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.7 10.1 GO:0003998 acylphosphatase activity(GO:0003998)
1.7 8.3 GO:0070644 vitamin D response element binding(GO:0070644)
1.6 12.7 GO:0035613 RNA stem-loop binding(GO:0035613)
1.6 31.7 GO:0050321 tau-protein kinase activity(GO:0050321)
1.6 45.9 GO:0070410 co-SMAD binding(GO:0070410)
1.5 54.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
1.5 28.7 GO:0008483 transaminase activity(GO:0008483)
1.5 31.6 GO:0000339 RNA cap binding(GO:0000339)
1.5 10.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.4 5.8 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
1.4 7.2 GO:0070728 leucine binding(GO:0070728)
1.4 2.8 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
1.4 9.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.4 62.7 GO:0003727 single-stranded RNA binding(GO:0003727)
1.3 6.7 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
1.3 4.0 GO:0015235 cobalamin transporter activity(GO:0015235)
1.3 43.7 GO:0015248 sterol transporter activity(GO:0015248)
1.3 18.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.2 9.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.2 15.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.2 45.2 GO:0031369 translation initiation factor binding(GO:0031369)
1.2 36.4 GO:0071889 14-3-3 protein binding(GO:0071889)
1.1 20.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
1.1 12.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.1 14.4 GO:0017091 AU-rich element binding(GO:0017091)
1.1 20.7 GO:0097602 cullin family protein binding(GO:0097602)
1.1 18.0 GO:0008327 methyl-CpG binding(GO:0008327)
1.0 20.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.0 3.9 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.0 37.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.9 13.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.9 62.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.9 19.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.9 23.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.9 87.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.9 26.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 12.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.8 22.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.8 12.5 GO:0043422 protein kinase B binding(GO:0043422)
0.8 2.3 GO:1990254 keratin filament binding(GO:1990254)
0.7 8.6 GO:0043274 phospholipase binding(GO:0043274)
0.7 9.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.7 26.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.7 40.8 GO:0019213 deacetylase activity(GO:0019213)
0.7 2.6 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.6 3.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.6 28.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.6 19.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.6 15.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.6 47.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.6 14.8 GO:0031489 myosin V binding(GO:0031489)
0.5 16.1 GO:0070064 proline-rich region binding(GO:0070064)
0.5 3.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.5 4.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.5 1.5 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.5 3.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.4 95.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 23.1 GO:0070035 ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.4 15.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.4 1.7 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.4 1.6 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.4 14.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 3.8 GO:0019902 phosphatase binding(GO:0019902)
0.4 7.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 2.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 7.5 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.3 35.5 GO:0019903 protein phosphatase binding(GO:0019903)
0.3 8.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 6.5 GO:0005537 mannose binding(GO:0005537)
0.3 2.9 GO:0070411 I-SMAD binding(GO:0070411)
0.3 16.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 6.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 7.9 GO:0015485 cholesterol binding(GO:0015485)
0.3 4.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 5.4 GO:0017166 vinculin binding(GO:0017166)
0.2 1.4 GO:0030492 hemoglobin binding(GO:0030492)
0.2 12.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 5.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 3.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 7.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 2.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 5.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 3.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 7.7 GO:0032947 protein complex scaffold(GO:0032947)
0.2 9.3 GO:0005504 fatty acid binding(GO:0005504)
0.2 10.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 1.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 4.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 40.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 0.5 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 1.0 GO:0039552 RIG-I binding(GO:0039552)
0.2 1.2 GO:0032405 MutLalpha complex binding(GO:0032405)
0.2 2.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.2 2.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 5.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 35.9 GO:0045296 cadherin binding(GO:0045296)
0.1 3.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 11.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 31.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 146.8 GO:0003723 RNA binding(GO:0003723)
0.1 3.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 1.8 GO:0019864 IgG binding(GO:0019864)
0.1 1.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 7.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 2.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 8.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 4.1 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 3.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 2.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 4.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 7.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 2.0 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 2.1 GO:0002020 protease binding(GO:0002020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 181.3 PID MYC PATHWAY C-MYC pathway
3.2 215.1 PID PLK1 PATHWAY PLK1 signaling events
2.0 105.8 PID AURORA B PATHWAY Aurora B signaling
1.9 111.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.8 88.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.3 61.6 PID ATM PATHWAY ATM pathway
0.9 2.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.9 26.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.8 21.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.8 59.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.8 38.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.7 26.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.7 53.3 PID E2F PATHWAY E2F transcription factor network
0.6 51.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.6 13.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.5 38.5 PID CDC42 PATHWAY CDC42 signaling events
0.5 9.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.5 46.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.5 16.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.4 10.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.4 18.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.4 7.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.3 15.4 PID ARF6 PATHWAY Arf6 signaling events
0.3 18.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 27.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 9.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 16.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 3.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 20.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 4.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 6.3 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 7.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 5.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 165.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
4.3 163.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
4.3 94.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
4.1 66.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
3.9 46.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
3.2 111.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
3.1 59.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
2.7 24.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
2.7 38.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
2.4 12.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
2.3 126.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.8 42.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
1.8 16.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.7 57.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
1.7 159.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
1.6 40.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.6 95.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
1.6 9.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.6 133.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
1.5 41.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.4 27.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.4 25.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.4 85.9 REACTOME G1 PHASE Genes involved in G1 Phase
1.3 13.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.2 21.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.2 20.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.1 38.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
1.1 15.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.0 21.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.0 43.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
1.0 46.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.9 18.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.8 32.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.8 19.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.8 15.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.8 26.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.8 7.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.7 4.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.7 42.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.7 6.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.7 17.4 REACTOME KINESINS Genes involved in Kinesins
0.6 45.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.6 102.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5 86.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.5 6.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 9.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 12.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.4 10.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.4 3.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 6.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.4 14.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.4 9.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 10.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 8.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 13.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.3 40.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 3.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.3 19.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 7.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 2.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 6.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 5.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 6.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 9.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 5.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 12.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 4.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins