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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NFIL3

Z-value: 1.84

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Transcription factors associated with NFIL3

Gene Symbol Gene ID Gene Info
NFIL3
ENSG00000165030.3 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIL3hg19_v2_chr9_-_94186131_94186174-0.186.5e-03Click!

Activity profile of NFIL3 motif

Sorted Z-values of NFIL3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_27468842 48.76 ENST00000523500.1
CLU
clusterin
chr5_+_150404904 27.97 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr4_-_88450612 27.68 ENST00000418378.1
ENST00000282470.6
SPARCL1
SPARC-like 1 (hevin)
chr10_-_5046042 27.07 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr12_-_91573132 26.82 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr11_-_5248294 26.64 ENST00000335295.4
HBB
hemoglobin, beta
chr12_-_91573316 25.18 ENST00000393155.1
DCN
decorin
chr12_-_91573249 23.96 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr9_+_139871948 23.58 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr8_-_27468945 23.38 ENST00000405140.3
CLU
clusterin
chr10_+_5005445 21.45 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr3_+_10068095 20.97 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr10_+_5005598 20.66 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr19_+_45409011 20.37 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr4_-_57524061 19.46 ENST00000508121.1
HOPX
HOP homeobox
chr12_-_91574142 18.44 ENST00000547937.1
DCN
decorin
chr4_-_88450244 18.43 ENST00000503414.1
SPARCL1
SPARC-like 1 (hevin)
chr8_-_27469196 18.38 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr1_+_169079823 18.25 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr21_+_27011584 18.08 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2
junctional adhesion molecule 2
chr14_+_93389425 17.64 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr6_-_116601044 17.39 ENST00000368608.3
TSPYL1
TSPY-like 1
chr1_-_230850043 17.10 ENST00000366667.4
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr6_-_116575226 16.68 ENST00000420283.1
TSPYL4
TSPY-like 4
chrX_-_102319092 16.52 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr5_-_131892501 16.14 ENST00000450655.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr14_-_21516590 15.76 ENST00000555026.1
NDRG2
NDRG family member 2
chr11_-_128894053 15.43 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr2_-_175712270 14.99 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chrX_-_13835461 14.90 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr12_+_10365404 14.72 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr12_-_91572278 14.66 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr3_+_49027308 14.57 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr5_+_150400124 14.52 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
GPX3
glutathione peroxidase 3 (plasma)
chr8_-_42397037 14.35 ENST00000342228.3
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr17_+_56315936 13.97 ENST00000543544.1
LPO
lactoperoxidase
chr11_+_62104897 13.80 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1
asparaginase like 1
chr11_-_5255696 13.31 ENST00000292901.3
ENST00000417377.1
HBD
hemoglobin, delta
chr6_-_46459099 13.25 ENST00000371374.1
RCAN2
regulator of calcineurin 2
chr16_-_53537105 13.04 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKTIP
AKT interacting protein
chr11_+_73358594 13.00 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr4_+_69962185 12.93 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr3_+_111717511 12.37 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr6_+_150690028 12.26 ENST00000229447.5
ENST00000344419.3
IYD
iodotyrosine deiodinase
chr10_-_97321112 12.24 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
SORBS1
sorbin and SH3 domain containing 1
chr11_-_64885111 12.04 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr10_-_69597810 11.86 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr1_+_168148273 11.82 ENST00000367830.3
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr5_+_36608422 11.76 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_79412357 11.62 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chrX_-_73072534 11.56 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr3_-_45883558 11.48 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr19_+_57791419 11.47 ENST00000537645.1
ZNF460
zinc finger protein 460
chr6_-_27782548 11.43 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr6_+_27833034 11.34 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr13_-_52378231 11.23 ENST00000280056.2
ENST00000444610.2
DHRS12
dehydrogenase/reductase (SDR family) member 12
chr6_+_121756809 11.14 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr11_+_17373273 11.03 ENST00000338965.4
NCR3LG1
natural killer cell cytotoxicity receptor 3 ligand 1
chr14_-_22005343 10.95 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr8_-_120651020 10.85 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr11_-_85376121 10.80 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr6_+_131894284 10.78 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr9_-_104249400 10.77 ENST00000374848.3
TMEM246
transmembrane protein 246
chr6_+_111580508 10.66 ENST00000368847.4
KIAA1919
KIAA1919
chr7_-_31380502 10.64 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr4_+_69962212 10.60 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr2_+_102927962 10.58 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr3_+_148447887 10.55 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr5_+_140739537 10.43 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr11_+_57365150 10.42 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr7_+_20686946 10.29 ENST00000443026.2
ENST00000406935.1
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_+_140165876 10.27 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr5_+_140227048 10.21 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr3_-_127455200 10.19 ENST00000398101.3
MGLL
monoglyceride lipase
chr2_+_149632783 10.18 ENST00000435030.1
KIF5C
kinesin family member 5C
chr9_+_37753795 10.13 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
TRMT10B
tRNA methyltransferase 10 homolog B (S. cerevisiae)
chr20_+_42839600 10.09 ENST00000439943.1
ENST00000437730.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr6_-_31940065 10.09 ENST00000375349.3
ENST00000337523.5
DXO
decapping exoribonuclease
chr17_-_41465674 10.06 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910
long intergenic non-protein coding RNA 910
chr10_-_95360983 10.03 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr22_-_44258360 9.96 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr11_-_5255861 9.89 ENST00000380299.3
HBD
hemoglobin, delta
chr11_+_61891445 9.86 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr1_+_92632542 9.71 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr17_-_76836729 9.66 ENST00000587783.1
ENST00000542802.3
ENST00000586531.1
ENST00000589424.1
ENST00000590546.2
USP36
ubiquitin specific peptidase 36
chr13_-_45010939 9.60 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr19_+_16999654 9.55 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr20_+_42839722 9.47 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr1_+_228353495 9.45 ENST00000366711.3
IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr17_+_38083977 9.35 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
RP11-387H17.4
chr17_-_4167142 9.32 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1
ankyrin repeat and FYVE domain containing 1
chr4_-_73935409 9.05 ENST00000507544.2
ENST00000295890.4
COX18
COX18 cytochrome C oxidase assembly factor
chr9_+_91933726 8.89 ENST00000534113.2
SECISBP2
SECIS binding protein 2
chrX_+_16737718 8.83 ENST00000380155.3
SYAP1
synapse associated protein 1
chr3_-_186288097 8.77 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr1_-_48937682 8.76 ENST00000371843.3
SPATA6
spermatogenesis associated 6
chr10_-_45474237 8.75 ENST00000448778.1
ENST00000298295.3
C10orf10
chromosome 10 open reading frame 10
chr4_+_185395947 8.71 ENST00000605834.1
RP11-326I11.3
RP11-326I11.3
chr19_+_45417921 8.70 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr11_+_17281900 8.69 ENST00000530527.1
NUCB2
nucleobindin 2
chr6_-_11779840 8.64 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr1_-_48937821 8.62 ENST00000396199.3
SPATA6
spermatogenesis associated 6
chr6_-_52668605 8.58 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr1_-_48937838 8.43 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr20_+_44036900 8.42 ENST00000443296.1
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_+_57831829 8.39 ENST00000321545.4
ZNF543
zinc finger protein 543
chr9_-_99381660 8.22 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr14_+_94577074 8.16 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr10_-_90712520 8.15 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_-_15850676 8.15 ENST00000440484.1
ENST00000333868.5
CASP9
caspase 9, apoptosis-related cysteine peptidase
chr15_+_91643442 8.14 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr10_-_97321165 8.14 ENST00000306402.6
SORBS1
sorbin and SH3 domain containing 1
chr1_+_20959943 8.12 ENST00000321556.4
PINK1
PTEN induced putative kinase 1
chr4_+_74275057 8.11 ENST00000511370.1
ALB
albumin
chr17_-_73851285 8.10 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2
WW domain binding protein 2
chr20_+_49575342 7.98 ENST00000244051.1
MOCS3
molybdenum cofactor synthesis 3
chr2_-_201936302 7.94 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr20_+_56136136 7.93 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr15_+_68924327 7.93 ENST00000543950.1
CORO2B
coronin, actin binding protein, 2B
chr17_-_36956155 7.79 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr1_+_152635854 7.78 ENST00000368784.1
LCE2D
late cornified envelope 2D
chr7_+_44646177 7.73 ENST00000443864.2
ENST00000447398.1
ENST00000449767.1
ENST00000419661.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr19_+_2841433 7.70 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
ZNF555
zinc finger protein 555
chr19_-_460996 7.65 ENST00000264554.6
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chrX_+_102469997 7.55 ENST00000372695.5
ENST00000372691.3
BEX4
brain expressed, X-linked 4
chr8_+_21916710 7.54 ENST00000523266.1
ENST00000519907.1
DMTN
dematin actin binding protein
chr13_-_52378281 7.52 ENST00000218981.1
DHRS12
dehydrogenase/reductase (SDR family) member 12
chr10_-_52645416 7.50 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr1_-_86043921 7.49 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr8_-_110703819 7.49 ENST00000532779.1
ENST00000534578.1
SYBU
syntabulin (syntaxin-interacting)
chr3_+_149191723 7.47 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr19_+_45418067 7.46 ENST00000589078.1
ENST00000586638.1
APOC1
apolipoprotein C-I
chr10_-_69597915 7.46 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr8_+_21916680 7.41 ENST00000358242.3
ENST00000415253.1
DMTN
dematin actin binding protein
chr9_-_95298314 7.38 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr5_+_156696362 7.36 ENST00000377576.3
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_16345245 7.33 ENST00000311890.9
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr4_+_159593418 7.27 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr12_+_124997766 7.26 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr16_+_3507985 7.25 ENST00000421765.3
ENST00000360862.5
ENST00000414063.2
ENST00000610180.1
ENST00000608993.1
NAA60
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
N-alpha-acetyltransferase 60
chr11_-_123525289 7.25 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr1_+_15671919 7.24 ENST00000314668.9
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr16_+_7382745 7.18 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_14993819 7.15 ENST00000396372.2
ENST00000361010.3
ENST00000359642.3
ENST00000331587.4
CALCA
calcitonin-related polypeptide alpha
chrX_-_140271249 7.13 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr9_-_104198042 7.11 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr10_-_27444143 7.06 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr10_-_61720640 7.04 ENST00000521074.1
ENST00000444900.1
C10orf40
chromosome 10 open reading frame 40
chr1_+_163039143 7.03 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
RGS4
regulator of G-protein signaling 4
chr20_-_43729750 7.03 ENST00000537075.1
ENST00000306117.1
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr5_-_139943830 7.02 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr5_-_133706695 7.01 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr17_-_34329084 6.99 ENST00000354059.4
ENST00000536149.1
CCL15
CCL14
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr10_-_7661623 6.96 ENST00000298441.6
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr12_-_71182695 6.88 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr11_+_124492749 6.87 ENST00000531667.1
ENST00000441174.3
ENST00000375005.4
TBRG1
transforming growth factor beta regulator 1
chr3_+_186383741 6.83 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr12_-_123215306 6.81 ENST00000356987.2
ENST00000436083.2
HCAR1
hydroxycarboxylic acid receptor 1
chr1_-_149832704 6.81 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
HIST2H4B
histone cluster 2, H4b
chr17_+_56315787 6.78 ENST00000262290.4
ENST00000421678.2
LPO
lactoperoxidase
chr1_+_149804218 6.76 ENST00000610125.1
HIST2H4A
histone cluster 2, H4a
chr7_-_15601595 6.72 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr5_+_140734570 6.70 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr6_+_27782788 6.64 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr5_-_140013275 6.55 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr19_+_10217270 6.52 ENST00000446223.1
PPAN
peter pan homolog (Drosophila)
chr15_+_42841008 6.51 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2
HAUS augmin-like complex, subunit 2
chr2_-_216300784 6.48 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr12_+_7014064 6.45 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr1_-_230513367 6.44 ENST00000321327.2
ENST00000525115.1
PGBD5
piggyBac transposable element derived 5
chrX_+_110339439 6.43 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr9_-_99064429 6.42 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr4_+_69681710 6.42 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_+_234602305 6.42 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr12_-_50297638 6.39 ENST00000320634.3
FAIM2
Fas apoptotic inhibitory molecule 2
chr15_-_78913521 6.39 ENST00000326828.5
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr4_-_153303658 6.30 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr18_-_5396271 6.28 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr4_+_668348 6.28 ENST00000511290.1
MYL5
myosin, light chain 5, regulatory
chr5_-_146435694 6.26 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr22_-_32334403 6.25 ENST00000543051.1
C22orf24
chromosome 22 open reading frame 24
chr10_-_124639062 6.22 ENST00000368898.3
ENST00000368896.1
ENST00000545804.1
FAM24B
CUZD1
family with sequence similarity 24, member B
CUB and zona pellucida-like domains 1
chr15_-_80634104 6.21 ENST00000561432.1
ENST00000558913.1
ENST00000558578.1
LINC00927
long intergenic non-protein coding RNA 927
chr12_-_6772303 6.20 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
ING4
inhibitor of growth family, member 4
chr1_+_196788887 6.17 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr11_-_72145426 6.17 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr14_-_70263979 6.16 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr19_-_38806560 6.13 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_-_117698765 6.12 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr12_+_7013897 6.11 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr1_+_156698708 6.09 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr10_+_86004802 6.08 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
RGR
retinal G protein coupled receptor
chr5_+_140762268 6.07 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr11_+_62495541 6.06 ENST00000530625.1
ENST00000513247.2
TTC9C
tetratricopeptide repeat domain 9C
chr13_-_33112899 6.03 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr15_-_30113676 6.02 ENST00000400011.2
TJP1
tight junction protein 1
chr3_+_155860751 6.02 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr19_+_36249057 6.02 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
C19orf55
chromosome 19 open reading frame 55
chr13_+_111855414 6.01 ENST00000375737.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_+_186435137 6.01 ENST00000447445.1
KNG1
kininogen 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIL3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 90.5 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
14.2 42.5 GO:0006982 response to lipid hydroperoxide(GO:0006982)
9.9 69.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
9.7 116.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
8.0 8.0 GO:0018307 enzyme active site formation(GO:0018307)
6.8 20.4 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
6.7 26.6 GO:0030185 nitric oxide transport(GO:0030185)
5.9 17.6 GO:2000705 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
5.7 17.1 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
5.4 16.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
4.6 18.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
4.0 16.2 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
3.8 11.4 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
3.6 10.8 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
3.5 21.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
3.4 13.5 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
3.2 12.7 GO:1904640 response to methionine(GO:1904640)
3.1 3.1 GO:0032466 negative regulation of cytokinesis(GO:0032466)
3.0 8.9 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
2.9 8.8 GO:0051684 maintenance of Golgi location(GO:0051684)
2.8 11.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
2.7 8.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
2.7 8.1 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of cellular respiration(GO:1901857) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
2.6 10.3 GO:0048749 compound eye development(GO:0048749)
2.5 5.0 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
2.5 14.9 GO:0070560 protein secretion by platelet(GO:0070560)
2.4 7.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
2.4 7.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
2.3 11.7 GO:0048807 female genitalia morphogenesis(GO:0048807)
2.3 9.3 GO:0055099 response to high density lipoprotein particle(GO:0055099)
2.3 11.5 GO:1903564 regulation of protein localization to cilium(GO:1903564)
2.2 13.2 GO:0016554 cytidine to uridine editing(GO:0016554)
2.1 14.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.1 6.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
2.0 6.1 GO:0090427 activation of meiosis(GO:0090427)
2.0 6.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.8 7.4 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
1.8 7.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.8 8.9 GO:0061370 testosterone biosynthetic process(GO:0061370)
1.8 1.8 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.8 8.8 GO:0080009 mRNA methylation(GO:0080009)
1.7 10.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.7 13.8 GO:0006528 asparagine metabolic process(GO:0006528)
1.7 8.5 GO:0009804 coumarin metabolic process(GO:0009804)
1.7 23.2 GO:0015671 oxygen transport(GO:0015671)
1.6 6.6 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.6 4.9 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.6 14.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.6 1.6 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
1.6 36.4 GO:0052695 cellular glucuronidation(GO:0052695)
1.6 4.7 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.6 7.9 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.6 9.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.6 6.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
1.5 9.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
1.5 4.5 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
1.5 6.0 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.5 14.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.5 2.9 GO:0052314 isoquinoline alkaloid metabolic process(GO:0033076) phytoalexin metabolic process(GO:0052314)
1.5 10.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.5 4.4 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
1.4 11.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.4 4.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
1.4 7.0 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.4 4.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
1.4 8.2 GO:0090131 mesenchyme migration(GO:0090131)
1.4 4.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
1.3 16.0 GO:0006570 tyrosine metabolic process(GO:0006570)
1.3 22.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.3 9.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
1.3 7.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
1.3 13.8 GO:0032025 response to cobalt ion(GO:0032025)
1.3 5.0 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.2 16.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.2 18.0 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.2 9.6 GO:0060155 platelet dense granule organization(GO:0060155)
1.2 3.6 GO:0006014 D-ribose metabolic process(GO:0006014)
1.2 7.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.2 3.5 GO:1904479 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
1.2 5.8 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
1.2 8.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.1 5.7 GO:0006875 cellular metal ion homeostasis(GO:0006875)
1.1 4.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.1 5.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.1 4.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.1 3.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.1 3.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.1 5.3 GO:0035617 stress granule disassembly(GO:0035617)
1.1 3.2 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
1.1 2.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
1.0 3.1 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.0 15.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.0 11.2 GO:0003351 epithelial cilium movement(GO:0003351)
1.0 3.0 GO:0009107 lipoate biosynthetic process(GO:0009107)
1.0 3.0 GO:2000724 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
1.0 10.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
1.0 3.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.0 5.9 GO:0016075 rRNA catabolic process(GO:0016075)
1.0 22.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.0 3.9 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
1.0 6.7 GO:0046485 ether lipid metabolic process(GO:0046485)
1.0 16.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.0 12.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.9 15.1 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.9 3.7 GO:1902159 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.9 25.9 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.9 7.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.9 8.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.9 9.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.9 20.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.9 6.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.9 9.9 GO:0016925 protein sumoylation(GO:0016925)
0.9 11.6 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.9 23.9 GO:0044458 motile cilium assembly(GO:0044458)
0.9 2.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.9 4.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.9 12.1 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.8 5.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.8 5.0 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.8 7.5 GO:0006527 arginine catabolic process(GO:0006527)
0.8 2.5 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.8 3.2 GO:0010193 response to ozone(GO:0010193)
0.8 4.8 GO:0002765 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.8 4.8 GO:0018343 protein farnesylation(GO:0018343)
0.8 5.5 GO:0070475 rRNA base methylation(GO:0070475)
0.8 2.4 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.8 3.9 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.8 2.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.8 3.9 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.8 3.9 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.8 13.9 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.8 4.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.8 3.8 GO:0003322 pancreatic A cell development(GO:0003322)
0.7 3.0 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.7 3.0 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.7 3.7 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.7 3.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.7 4.4 GO:0051012 microtubule sliding(GO:0051012)
0.7 0.7 GO:0006711 estrogen catabolic process(GO:0006711)
0.7 24.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.7 7.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.7 3.6 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.7 22.7 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.7 10.6 GO:0014029 neural crest formation(GO:0014029)
0.7 2.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.7 2.8 GO:0019086 late viral transcription(GO:0019086)
0.7 19.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.7 4.0 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.7 2.0 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.7 6.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 3.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.7 3.9 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.7 7.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.7 3.9 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.6 15.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.6 16.7 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
0.6 1.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.6 3.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.6 4.3 GO:0035799 ureter maturation(GO:0035799)
0.6 2.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.6 3.6 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.6 4.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.6 5.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.6 5.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.6 1.1 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.5 1.6 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.5 3.3 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.5 5.9 GO:0035330 regulation of hippo signaling(GO:0035330)
0.5 2.7 GO:0006311 meiotic gene conversion(GO:0006311) male meiosis chromosome segregation(GO:0007060)
0.5 1.1 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.5 7.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.5 1.0 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.5 9.8 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.5 7.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.5 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.5 4.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.5 14.5 GO:0010107 potassium ion import(GO:0010107)
0.5 3.4 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.5 4.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.5 4.9 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5 6.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.5 2.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.5 4.2 GO:0015705 iodide transport(GO:0015705)
0.5 3.2 GO:0042048 olfactory behavior(GO:0042048)
0.5 2.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.5 4.6 GO:0016322 neuron remodeling(GO:0016322)
0.5 1.4 GO:0043605 cellular amide catabolic process(GO:0043605)
0.5 7.8 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.5 16.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.5 3.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 3.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.5 13.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.5 5.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.4 6.3 GO:0042737 drug catabolic process(GO:0042737)
0.4 2.7 GO:0042908 xenobiotic transport(GO:0042908)
0.4 2.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.4 3.5 GO:0070166 enamel mineralization(GO:0070166)
0.4 6.6 GO:0045475 locomotor rhythm(GO:0045475)
0.4 1.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.4 1.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.4 3.8 GO:0097120 receptor localization to synapse(GO:0097120)
0.4 3.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 1.3 GO:0086098 angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.4 3.3 GO:0007506 gonadal mesoderm development(GO:0007506)
0.4 13.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.4 5.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.4 1.2 GO:1903487 regulation of lactation(GO:1903487)
0.4 4.1 GO:0000050 urea cycle(GO:0000050)
0.4 14.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.4 1.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.4 5.6 GO:0017144 drug metabolic process(GO:0017144)
0.4 2.8 GO:0001842 neural fold formation(GO:0001842)
0.4 4.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.4 2.0 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.4 1.9 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.4 1.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.4 2.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 3.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.4 10.6 GO:0021542 dentate gyrus development(GO:0021542)
0.4 2.2 GO:0021915 neural tube development(GO:0021915)
0.4 8.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.4 4.4 GO:0015871 choline transport(GO:0015871)
0.4 14.1 GO:0033014 tetrapyrrole biosynthetic process(GO:0033014)
0.4 2.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.4 1.4 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.4 2.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 3.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 2.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 2.4 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.3 2.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.3 6.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.3 1.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.3 3.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.0 GO:0051697 protein delipidation(GO:0051697)
0.3 6.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 2.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.3 1.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 0.7 GO:0070428 nitric oxide production involved in inflammatory response(GO:0002537) negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.3 3.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.3 9.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 2.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 3.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 2.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 0.6 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.3 4.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.3 3.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.3 0.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.3 3.5 GO:0006108 oxaloacetate metabolic process(GO:0006107) malate metabolic process(GO:0006108)
0.3 2.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 46.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 1.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.3 0.9 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.3 5.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 1.7 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.3 2.5 GO:0031167 rRNA methylation(GO:0031167)
0.3 5.0 GO:0005513 detection of calcium ion(GO:0005513)
0.3 3.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.3 13.0 GO:0007602 phototransduction(GO:0007602)
0.3 1.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.3 0.8 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.3 1.3 GO:0022605 ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165)
0.3 1.8 GO:0006750 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.3 2.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 2.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 1.0 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.2 2.2 GO:0034311 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.2 3.1 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.2 11.3 GO:0018149 peptide cross-linking(GO:0018149)
0.2 6.0 GO:0030488 tRNA methylation(GO:0030488)
0.2 6.2 GO:0010039 response to iron ion(GO:0010039)
0.2 0.7 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 2.3 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.2 2.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 4.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 4.5 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 1.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 10.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 3.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 1.7 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 3.6 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.2 2.3 GO:0006907 pinocytosis(GO:0006907)
0.2 5.7 GO:0006400 tRNA modification(GO:0006400)
0.2 3.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 2.9 GO:0034115 negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.2 1.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 2.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 3.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 6.5 GO:0033344 cholesterol efflux(GO:0033344)
0.2 0.6 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.2 2.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.2 6.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.2 2.8 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 2.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.2 1.0 GO:0048754 branching morphogenesis of an epithelial tube(GO:0048754)
0.2 1.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.2 GO:0071105 response to interleukin-11(GO:0071105)
0.2 5.0 GO:0072337 modified amino acid transport(GO:0072337)
0.2 6.3 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 5.2 GO:0046710 GDP metabolic process(GO:0046710)
0.2 3.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 5.1 GO:0015695 organic cation transport(GO:0015695)
0.2 3.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 1.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 6.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 14.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.2 1.9 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2 7.2 GO:0001881 receptor recycling(GO:0001881)
0.2 7.0 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.2 2.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 14.4 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.2 1.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 8.3 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.2 0.8 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 3.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.0 GO:0034505 tooth mineralization(GO:0034505)
0.1 2.3 GO:0051194 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 4.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.5 GO:0009299 mRNA transcription(GO:0009299)
0.1 1.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 6.5 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.7 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 2.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 5.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.5 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 6.1 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 1.7 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 2.6 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 3.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 3.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 3.0 GO:0048854 brain morphogenesis(GO:0048854)
0.1 0.6 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.7 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.1 1.2 GO:0042730 fibrinolysis(GO:0042730)
0.1 5.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.4 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 12.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 3.8 GO:0003197 endocardial cushion development(GO:0003197)
0.1 5.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 4.0 GO:0098930 axonal transport(GO:0098930)
0.1 1.9 GO:0032094 response to food(GO:0032094)
0.1 9.8 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 5.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 3.2 GO:0032720 negative regulation of tumor necrosis factor production(GO:0032720)
0.1 2.7 GO:0006953 acute-phase response(GO:0006953)
0.1 1.1 GO:0007350 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 3.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 2.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 2.1 GO:0001947 heart looping(GO:0001947)
0.1 1.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 0.2 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 7.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 1.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 6.3 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 1.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 2.0 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 2.0 GO:0006298 mismatch repair(GO:0006298)
0.1 0.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.0 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.5 GO:0008347 glial cell migration(GO:0008347)
0.1 1.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.7 GO:0003094 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.1 2.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 4.8 GO:0007586 digestion(GO:0007586)
0.1 4.7 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.8 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.2 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 5.2 GO:0008366 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.1 8.1 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 2.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.3 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 2.1 GO:0050905 neuromuscular process(GO:0050905)
0.0 29.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 2.3 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 3.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.9 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.1 GO:0043068 positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.4 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.6 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 31.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
7.8 109.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
7.6 30.2 GO:0097224 sperm connecting piece(GO:0097224)
6.8 20.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
6.5 90.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
4.4 13.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
4.1 20.4 GO:0005899 insulin receptor complex(GO:0005899)
3.7 11.0 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
3.5 13.8 GO:0043293 apoptosome(GO:0043293)
3.3 13.0 GO:0070695 FHF complex(GO:0070695)
3.2 3.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
2.5 12.5 GO:0000801 central element(GO:0000801)
2.1 25.4 GO:0005833 hemoglobin complex(GO:0005833)
2.0 8.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.9 9.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.6 17.6 GO:0042583 chromaffin granule(GO:0042583)
1.6 20.3 GO:0005577 fibrinogen complex(GO:0005577)
1.5 30.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.4 7.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.3 3.9 GO:0098536 deuterosome(GO:0098536)
1.2 12.0 GO:0097449 astrocyte projection(GO:0097449)
1.2 4.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
1.2 18.8 GO:0042627 chylomicron(GO:0042627)
1.2 3.5 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
1.1 10.2 GO:0035253 ciliary rootlet(GO:0035253)
1.1 5.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.1 5.4 GO:0005602 complement component C1 complex(GO:0005602)
1.0 7.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.0 4.9 GO:0008275 gamma-tubulin small complex(GO:0008275)
1.0 3.9 GO:0072536 interleukin-23 receptor complex(GO:0072536)
1.0 2.9 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.0 26.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.9 19.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.9 6.0 GO:1990635 proximal dendrite(GO:1990635)
0.9 12.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.8 5.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.8 5.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.8 14.4 GO:0005922 connexon complex(GO:0005922)
0.8 13.3 GO:0033270 paranode region of axon(GO:0033270)
0.7 3.7 GO:0032021 NELF complex(GO:0032021)
0.7 2.9 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.7 2.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.6 4.5 GO:0030870 Mre11 complex(GO:0030870)
0.6 3.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.6 1.2 GO:0033186 CAF-1 complex(GO:0033186)
0.6 4.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.6 2.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.6 7.5 GO:0097433 dense body(GO:0097433)
0.6 23.5 GO:0032590 dendrite membrane(GO:0032590)
0.5 4.4 GO:0036157 outer dynein arm(GO:0036157)
0.5 7.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 8.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 6.0 GO:0005921 gap junction(GO:0005921)
0.5 2.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.5 1.9 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.5 6.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 11.5 GO:0002080 acrosomal membrane(GO:0002080)
0.5 3.7 GO:0044294 dendritic growth cone(GO:0044294)
0.4 10.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.4 3.5 GO:0045179 apical cortex(GO:0045179)
0.4 45.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.4 5.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4 23.9 GO:0000786 nucleosome(GO:0000786)
0.4 4.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 2.0 GO:0032389 MutLalpha complex(GO:0032389)
0.4 5.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 2.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 4.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 6.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.4 10.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4 5.8 GO:0097440 apical dendrite(GO:0097440)
0.4 3.2 GO:0005638 lamin filament(GO:0005638)
0.4 1.8 GO:0031905 early endosome lumen(GO:0031905)
0.4 1.8 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.4 1.4 GO:0031673 H zone(GO:0031673)
0.4 2.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.3 1.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 2.1 GO:0034464 BBSome(GO:0034464)
0.3 5.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 6.6 GO:0097225 sperm midpiece(GO:0097225)
0.3 1.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.3 8.8 GO:0034451 centriolar satellite(GO:0034451)
0.3 2.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 3.9 GO:0016342 catenin complex(GO:0016342)
0.3 34.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.3 3.8 GO:0060077 inhibitory synapse(GO:0060077)
0.3 13.9 GO:0097546 ciliary base(GO:0097546)
0.3 2.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 0.6 GO:0097679 other organism cytoplasm(GO:0097679)
0.3 3.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 4.4 GO:0030478 actin cap(GO:0030478)
0.3 2.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 4.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 2.5 GO:0016013 syntrophin complex(GO:0016013)
0.3 1.9 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3 2.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 13.7 GO:0016235 aggresome(GO:0016235)
0.2 12.3 GO:0001533 cornified envelope(GO:0001533)
0.2 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 14.8 GO:0036064 ciliary basal body(GO:0036064)
0.2 2.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.2 2.0 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 16.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 18.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 14.3 GO:0034707 chloride channel complex(GO:0034707)
0.2 80.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 2.4 GO:0030008 TRAPP complex(GO:0030008)
0.2 1.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 10.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 6.7 GO:0048786 presynaptic active zone(GO:0048786)
0.2 0.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 29.4 GO:0030426 growth cone(GO:0030426)
0.2 10.7 GO:0005796 Golgi lumen(GO:0005796)
0.2 6.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 34.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 0.8 GO:0036128 CatSper complex(GO:0036128)
0.1 2.1 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 12.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 14.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.5 GO:0005916 fascia adherens(GO:0005916)
0.1 8.9 GO:0035580 specific granule lumen(GO:0035580)
0.1 4.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 12.3 GO:0005776 autophagosome(GO:0005776)
0.1 2.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 6.4 GO:0015030 Cajal body(GO:0015030)
0.1 1.7 GO:0097342 ripoptosome(GO:0097342)
0.1 11.7 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 2.6 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.9 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.1 GO:0031906 late endosome lumen(GO:0031906)
0.1 6.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.7 GO:0001772 immunological synapse(GO:0001772)
0.1 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.6 GO:0002102 podosome(GO:0002102)
0.1 1.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 2.7 GO:0005859 muscle myosin complex(GO:0005859)
0.1 14.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 181.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.1 GO:0036513 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.0 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 8.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.9 GO:0031514 motile cilium(GO:0031514)
0.0 6.4 GO:0045202 synapse(GO:0045202)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
11.5 69.2 GO:0047115 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
6.8 20.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
6.2 18.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
5.9 23.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
5.6 33.6 GO:0030492 hemoglobin binding(GO:0030492)
5.4 16.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
5.0 15.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
4.5 90.5 GO:0051787 misfolded protein binding(GO:0051787)
4.5 13.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
3.9 42.5 GO:0008430 selenium binding(GO:0008430)
3.1 9.3 GO:0002113 interleukin-33 binding(GO:0002113)
3.1 18.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
2.9 8.8 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
2.7 10.8 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.7 16.0 GO:0004447 iodide peroxidase activity(GO:0004447)
2.6 7.9 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.6 7.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.5 30.2 GO:0032027 myosin light chain binding(GO:0032027)
2.5 7.4 GO:0070052 collagen V binding(GO:0070052)
2.3 16.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
2.2 162.0 GO:0050840 extracellular matrix binding(GO:0050840)
2.2 8.9 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
2.2 13.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.2 6.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
2.2 8.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
2.1 23.2 GO:0005344 oxygen transporter activity(GO:0005344)
1.9 11.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
1.8 5.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.8 7.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
1.8 29.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.8 10.8 GO:0015057 thrombin receptor activity(GO:0015057)
1.8 7.1 GO:0031716 calcitonin receptor binding(GO:0031716)
1.8 8.9 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.7 5.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.7 23.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.7 5.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.7 11.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.6 12.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.6 6.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.6 9.5 GO:0048039 ubiquinone binding(GO:0048039)
1.5 6.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.5 4.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
1.5 8.9 GO:0004882 androgen receptor activity(GO:0004882)
1.4 7.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.4 1.4 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
1.4 4.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
1.4 4.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
1.4 4.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.4 8.2 GO:1903135 cupric ion binding(GO:1903135)
1.3 8.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.3 15.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
1.3 49.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.3 5.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.3 5.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.2 3.7 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
1.2 4.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
1.2 6.0 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
1.2 4.7 GO:0019862 IgA binding(GO:0019862)
1.2 7.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.1 3.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.1 4.5 GO:0061714 folic acid receptor activity(GO:0061714)
1.1 4.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
1.1 18.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.1 9.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
1.1 3.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
1.1 14.7 GO:0030957 Tat protein binding(GO:0030957)
1.0 3.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.0 3.0 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
1.0 3.0 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
1.0 3.0 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
1.0 3.9 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
1.0 2.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.0 14.3 GO:0016918 retinal binding(GO:0016918)
0.9 17.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.9 4.5 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.9 5.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.9 7.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.9 5.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 7.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.8 7.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.8 5.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.8 2.5 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.8 8.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.8 21.0 GO:0005521 lamin binding(GO:0005521)
0.8 2.4 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.8 10.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.8 10.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.8 2.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.8 5.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.8 6.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.8 3.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.8 11.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.7 3.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.7 2.9 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.7 4.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.7 3.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.7 16.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.7 4.0 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.7 2.7 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.6 7.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 4.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.6 5.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.6 1.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 6.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.6 1.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.6 3.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.6 1.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.6 16.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.6 13.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.6 1.8 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.6 6.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.6 7.4 GO:0015643 toxic substance binding(GO:0015643)
0.6 1.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.6 9.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 2.7 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.5 1.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.5 2.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 1.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5 1.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.5 10.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 2.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5 14.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 11.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.5 13.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 3.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.5 6.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.5 2.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 3.6 GO:0015232 heme transporter activity(GO:0015232)
0.4 1.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 5.7 GO:0042608 T cell receptor binding(GO:0042608)
0.4 3.0 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 2.5 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.4 3.3 GO:1990405 protein antigen binding(GO:1990405)
0.4 18.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 2.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.4 1.2 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 3.9 GO:0051425 PTB domain binding(GO:0051425)
0.4 2.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.4 1.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.4 1.5 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.4 4.9 GO:0051184 cofactor transporter activity(GO:0051184)
0.4 9.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 4.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 8.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 5.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 4.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.3 7.3 GO:0031005 filamin binding(GO:0031005)
0.3 3.8 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3 2.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 1.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 5.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 1.0 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.3 7.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.3 4.6 GO:0004875 complement receptor activity(GO:0004875)
0.3 15.8 GO:0005158 insulin receptor binding(GO:0005158)
0.3 2.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 5.8 GO:0019864 IgG binding(GO:0019864)
0.3 1.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 15.0 GO:0030507 spectrin binding(GO:0030507)
0.3 9.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 30.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 10.3 GO:0042056 chemoattractant activity(GO:0042056)
0.3 0.9 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3 9.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 3.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 1.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 1.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 3.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.3 5.3 GO:0015485 cholesterol binding(GO:0015485)
0.3 3.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 2.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 6.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 1.0 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 4.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 14.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 2.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 3.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 4.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 2.6 GO:0015266 protein channel activity(GO:0015266)
0.2 2.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 3.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 3.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 9.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 5.6 GO:0070403 NAD+ binding(GO:0070403)
0.2 18.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 3.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 7.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 2.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 4.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 3.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.6 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 3.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 3.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 4.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 4.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 5.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 1.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 4.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 3.3 GO:0042166 acetylcholine binding(GO:0042166)
0.2 25.9 GO:0017124 SH3 domain binding(GO:0017124)
0.2 5.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 3.9 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 1.0 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 1.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.3 GO:0043495 protein anchor(GO:0043495)
0.2 3.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2 6.5 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.2 24.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.6 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.2 7.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 3.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 3.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.0 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 3.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 3.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.8 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 4.7 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.1 2.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 3.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 22.2 GO:0051015 actin filament binding(GO:0051015)
0.1 0.8 GO:0048156 tau protein binding(GO:0048156)
0.1 4.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.3 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 2.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 2.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.6 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 2.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 1.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 9.7 GO:0005179 hormone activity(GO:0005179)
0.1 7.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 14.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 2.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 18.2 GO:0003779 actin binding(GO:0003779)
0.1 12.2 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.2 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.7 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217)
0.1 1.7 GO:0005123 death receptor binding(GO:0005123)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 4.1 GO:0005262 calcium channel activity(GO:0005262)
0.1 2.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.1 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 27.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.1 GO:0019843 rRNA binding(GO:0019843)
0.0 1.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 3.4 GO:0044325 ion channel binding(GO:0044325)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956)
0.0 1.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 34.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.0 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.9 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.3 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 112.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.9 15.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.8 19.4 PID IL5 PATHWAY IL5-mediated signaling events
0.7 102.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.7 13.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.6 40.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.5 26.1 PID ATM PATHWAY ATM pathway
0.5 16.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.5 3.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 9.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.4 9.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.4 3.6 PID IL3 PATHWAY IL3-mediated signaling events
0.4 15.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.4 2.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.4 16.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 17.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 7.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.4 91.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 20.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 16.4 PID ARF6 PATHWAY Arf6 signaling events
0.3 75.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 6.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 7.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 2.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 12.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 18.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 12.4 PID INSULIN PATHWAY Insulin Pathway
0.3 10.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.3 11.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 7.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 3.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 7.2 PID RAS PATHWAY Regulation of Ras family activation
0.2 7.0 PID MYC PATHWAY C-MYC pathway
0.2 5.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 5.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 11.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 4.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 7.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 10.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 7.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 5.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.1 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 13.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 109.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.7 45.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.6 21.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.4 34.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.2 16.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.1 14.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
1.0 19.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.0 12.3 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.9 8.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.8 3.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.8 119.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.8 14.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.8 45.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.7 12.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7 12.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.7 37.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.7 8.9 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.7 16.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.7 11.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6 8.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.6 4.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.5 12.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.5 14.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 1.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.5 5.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 19.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.5 13.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5 15.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 6.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 6.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.4 6.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 21.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 16.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.4 3.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.4 5.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 11.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.3 10.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 15.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 7.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 18.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 3.2 REACTOME OPSINS Genes involved in Opsins
0.3 2.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 2.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 3.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.3 4.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 3.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 6.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 4.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 7.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 0.2 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.2 4.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 6.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 4.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 1.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 15.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 2.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 31.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.2 3.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 3.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 2.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 9.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 1.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 2.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 20.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 5.8 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.1 3.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 5.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 3.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 4.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 45.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 4.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 5.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.8 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 5.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis