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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for NFIX_NFIB
Z-value: 3.18
Motif logo
Transcription factors associated with NFIX_NFIB
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NFIX
|
ENSG00000008441.12 | nuclear factor I X |
|
NFIB
|
ENSG00000147862.10 | nuclear factor I B |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFIB | hg19_v2_chr9_-_14308004_14308041 | 0.61 | 3.1e-23 | Click! |
| NFIX | hg19_v2_chr19_+_13106383_13106423, hg19_v2_chr19_+_13134772_13134846, hg19_v2_chr19_+_13135731_13135787 | 0.35 | 9.9e-08 | Click! |
Activity profile of NFIX_NFIB motif
Sorted Z-values of NFIX_NFIB motif
Network of associatons between targets according to the STRING database.
First level regulatory network of NFIX_NFIB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 19.5 | 58.5 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 15.8 | 47.5 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 12.2 | 48.9 | GO:0003330 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 12.1 | 48.3 | GO:0070426 | positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434) |
| 12.1 | 48.3 | GO:0030185 | nitric oxide transport(GO:0030185) |
| 12.0 | 47.8 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 11.1 | 66.5 | GO:1902847 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 10.5 | 42.1 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 10.5 | 41.8 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 10.3 | 31.0 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 10.3 | 144.6 | GO:0015671 | oxygen transport(GO:0015671) |
| 9.8 | 29.3 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 9.5 | 9.5 | GO:1901655 | cellular response to ketone(GO:1901655) |
| 9.4 | 18.8 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 9.2 | 45.9 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 9.1 | 27.2 | GO:0043012 | regulation of fusion of sperm to egg plasma membrane(GO:0043012) |
| 9.0 | 27.1 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 8.9 | 35.7 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 8.7 | 43.3 | GO:0048807 | female genitalia morphogenesis(GO:0048807) |
| 8.4 | 33.4 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 8.3 | 8.3 | GO:0043650 | glutamate biosynthetic process(GO:0006537) dicarboxylic acid biosynthetic process(GO:0043650) |
| 8.2 | 16.4 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 7.8 | 15.7 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 7.8 | 23.4 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 7.8 | 7.8 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 7.7 | 15.5 | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 7.5 | 29.9 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 7.4 | 36.9 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 7.3 | 36.4 | GO:0072313 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 7.2 | 21.6 | GO:0001798 | positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) |
| 7.0 | 20.9 | GO:0048691 | modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
| 6.9 | 34.4 | GO:0034442 | regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) |
| 6.8 | 27.2 | GO:1902612 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 6.7 | 67.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 6.7 | 20.2 | GO:1903625 | negative regulation of DNA catabolic process(GO:1903625) |
| 6.5 | 6.5 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
| 6.3 | 31.7 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 6.3 | 18.9 | GO:1904397 | negative regulation of neuromuscular junction development(GO:1904397) |
| 6.0 | 23.8 | GO:0035054 | embryonic heart tube anterior/posterior pattern specification(GO:0035054) |
| 5.7 | 17.2 | GO:0001300 | chronological cell aging(GO:0001300) |
| 5.7 | 28.6 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 5.7 | 17.1 | GO:0009258 | 10-formyltetrahydrofolate catabolic process(GO:0009258) |
| 5.7 | 17.1 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 5.7 | 28.3 | GO:0044856 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 5.6 | 22.4 | GO:0071231 | cellular response to folic acid(GO:0071231) |
| 5.6 | 16.7 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056) |
| 5.6 | 27.8 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 5.4 | 16.2 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 5.3 | 26.7 | GO:0030070 | insulin processing(GO:0030070) |
| 5.3 | 5.3 | GO:0035865 | cellular response to potassium ion(GO:0035865) |
| 5.3 | 10.6 | GO:0045646 | regulation of erythrocyte differentiation(GO:0045646) |
| 5.3 | 68.5 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 5.2 | 15.7 | GO:0033861 | negative regulation of NAD(P)H oxidase activity(GO:0033861) |
| 5.2 | 15.5 | GO:1900104 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 5.1 | 5.1 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 5.1 | 15.4 | GO:0035603 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915) |
| 5.0 | 15.1 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 5.0 | 5.0 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 4.9 | 14.8 | GO:1990764 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 4.9 | 24.5 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 4.9 | 9.8 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 4.9 | 19.5 | GO:0061364 | apoptotic process involved in luteolysis(GO:0061364) |
| 4.8 | 9.7 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 4.8 | 19.2 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 4.8 | 14.3 | GO:0031630 | regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) |
| 4.7 | 18.8 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 4.7 | 14.1 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 4.7 | 23.3 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 4.6 | 18.5 | GO:0072376 | protein activation cascade(GO:0072376) |
| 4.6 | 23.1 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 4.6 | 13.7 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
| 4.5 | 22.7 | GO:0035106 | operant conditioning(GO:0035106) |
| 4.5 | 58.7 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 4.5 | 17.9 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 4.5 | 13.4 | GO:0033212 | iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308) |
| 4.5 | 13.4 | GO:0019072 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 4.5 | 13.4 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 4.5 | 13.4 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
| 4.4 | 26.5 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 4.4 | 22.0 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 4.4 | 17.6 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 4.4 | 4.4 | GO:0060734 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) |
| 4.3 | 17.1 | GO:0042361 | menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377) |
| 4.3 | 12.8 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 4.3 | 34.1 | GO:0015705 | iodide transport(GO:0015705) |
| 4.2 | 12.7 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 4.2 | 16.9 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
| 4.2 | 96.1 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 4.2 | 33.3 | GO:2000664 | positive regulation of interleukin-5 secretion(GO:2000664) |
| 4.2 | 4.2 | GO:0006145 | purine nucleobase catabolic process(GO:0006145) |
| 4.1 | 49.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 4.1 | 49.5 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 4.1 | 16.2 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 4.0 | 24.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 4.0 | 12.0 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 4.0 | 4.0 | GO:2000302 | positive regulation of synaptic vesicle exocytosis(GO:2000302) |
| 4.0 | 32.0 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 4.0 | 12.0 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 4.0 | 23.8 | GO:2000322 | regulation of glucocorticoid receptor signaling pathway(GO:2000322) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 3.9 | 15.7 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 3.9 | 3.9 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 3.9 | 27.3 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 3.9 | 11.7 | GO:0032887 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 3.9 | 11.6 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 3.8 | 42.1 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 3.8 | 19.1 | GO:0051946 | regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
| 3.8 | 3.8 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 3.8 | 30.5 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 3.8 | 15.2 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 3.8 | 11.3 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
| 3.8 | 11.3 | GO:0038188 | cholecystokinin signaling pathway(GO:0038188) |
| 3.7 | 14.8 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) |
| 3.7 | 11.0 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 3.7 | 40.5 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 3.7 | 14.6 | GO:0042335 | cuticle development(GO:0042335) |
| 3.6 | 10.9 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 3.6 | 10.9 | GO:1990637 | response to prolactin(GO:1990637) |
| 3.6 | 3.6 | GO:0032344 | regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347) |
| 3.6 | 10.8 | GO:1904640 | response to methionine(GO:1904640) |
| 3.6 | 10.7 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 3.5 | 10.6 | GO:0035915 | pore formation in membrane of other organism(GO:0035915) |
| 3.5 | 63.6 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 3.5 | 7.1 | GO:0001501 | skeletal system development(GO:0001501) |
| 3.5 | 3.5 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 3.5 | 13.9 | GO:0097113 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 3.5 | 20.8 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 3.5 | 10.4 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 3.4 | 3.4 | GO:2000584 | regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 3.4 | 6.9 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 3.4 | 3.4 | GO:0003285 | septum secundum development(GO:0003285) |
| 3.4 | 3.4 | GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) |
| 3.4 | 10.1 | GO:2001303 | lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303) |
| 3.4 | 10.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 3.3 | 13.4 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 3.3 | 13.3 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 3.3 | 32.9 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 3.3 | 22.9 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 3.3 | 13.1 | GO:0021633 | optic nerve structural organization(GO:0021633) |
| 3.3 | 9.8 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 3.2 | 22.7 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 3.2 | 9.7 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 3.2 | 9.7 | GO:0051037 | histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 3.2 | 25.7 | GO:0006531 | aspartate metabolic process(GO:0006531) |
| 3.2 | 12.8 | GO:0031443 | fast-twitch skeletal muscle fiber contraction(GO:0031443) |
| 3.2 | 9.5 | GO:0002125 | maternal aggressive behavior(GO:0002125) |
| 3.2 | 18.9 | GO:0010873 | positive regulation of cholesterol esterification(GO:0010873) |
| 3.1 | 9.4 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 3.1 | 3.1 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 3.1 | 3.1 | GO:0099545 | trans-synaptic signaling by trans-synaptic complex(GO:0099545) |
| 3.1 | 6.2 | GO:0032765 | positive regulation of mast cell cytokine production(GO:0032765) |
| 3.1 | 18.7 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 3.1 | 37.3 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 3.1 | 9.3 | GO:0048241 | epinephrine transport(GO:0048241) |
| 3.1 | 27.7 | GO:0036017 | response to erythropoietin(GO:0036017) |
| 3.1 | 21.5 | GO:0071205 | protein localization to juxtaparanode region of axon(GO:0071205) |
| 3.1 | 3.1 | GO:0033687 | osteoblast proliferation(GO:0033687) |
| 3.1 | 6.1 | GO:0002118 | aggressive behavior(GO:0002118) |
| 3.1 | 6.1 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 3.0 | 18.1 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
| 3.0 | 6.0 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 3.0 | 24.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 3.0 | 3.0 | GO:0033561 | regulation of water loss via skin(GO:0033561) |
| 3.0 | 17.8 | GO:0019732 | antifungal humoral response(GO:0019732) |
| 3.0 | 3.0 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 3.0 | 8.9 | GO:0030311 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 2.9 | 38.1 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 2.9 | 2.9 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 2.9 | 14.6 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
| 2.9 | 8.7 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
| 2.9 | 8.7 | GO:1902722 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) positive regulation of prolactin secretion(GO:1902722) |
| 2.9 | 2.9 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 2.9 | 11.5 | GO:0044334 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 2.9 | 11.5 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 2.8 | 2.8 | GO:0070474 | positive regulation of uterine smooth muscle contraction(GO:0070474) |
| 2.8 | 2.8 | GO:0060157 | urinary bladder development(GO:0060157) |
| 2.8 | 8.5 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 2.8 | 8.5 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 2.8 | 19.7 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 2.8 | 14.0 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 2.8 | 27.9 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 2.8 | 30.6 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 2.8 | 44.5 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 2.8 | 38.8 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 2.8 | 22.1 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
| 2.8 | 8.3 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 2.7 | 8.2 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 2.7 | 8.2 | GO:0040034 | regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505) |
| 2.7 | 32.6 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 2.7 | 8.1 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 2.7 | 13.5 | GO:1902731 | negative regulation of chondrocyte proliferation(GO:1902731) |
| 2.7 | 24.0 | GO:0051552 | flavone metabolic process(GO:0051552) |
| 2.7 | 8.0 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 2.7 | 10.6 | GO:0009182 | purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) |
| 2.6 | 10.6 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 2.6 | 7.9 | GO:1990502 | dense core granule maturation(GO:1990502) |
| 2.6 | 2.6 | GO:0061110 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 2.6 | 7.9 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 2.6 | 7.9 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 2.6 | 10.5 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 2.6 | 10.5 | GO:0006562 | proline catabolic process(GO:0006562) |
| 2.6 | 10.5 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 2.6 | 7.9 | GO:1902081 | regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 2.6 | 23.5 | GO:2000370 | positive regulation of clathrin-mediated endocytosis(GO:2000370) |
| 2.6 | 10.5 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 2.6 | 7.8 | GO:0061055 | myotome development(GO:0061055) |
| 2.6 | 38.8 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 2.6 | 46.4 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 2.6 | 7.7 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 2.6 | 5.1 | GO:0051659 | maintenance of mitochondrion location(GO:0051659) |
| 2.6 | 2.6 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
| 2.6 | 18.0 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 2.6 | 10.2 | GO:0007525 | somatic muscle development(GO:0007525) |
| 2.6 | 2.6 | GO:0010046 | response to mycotoxin(GO:0010046) |
| 2.5 | 5.1 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 2.5 | 7.6 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 2.5 | 2.5 | GO:0042761 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation(GO:0030497) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 2.5 | 10.1 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 2.5 | 15.1 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 2.5 | 30.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 2.5 | 10.0 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 2.5 | 14.9 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 2.5 | 49.1 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 2.4 | 2.4 | GO:0014734 | skeletal muscle hypertrophy(GO:0014734) |
| 2.4 | 12.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 2.4 | 19.5 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 2.4 | 4.8 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 2.4 | 7.2 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 2.4 | 38.5 | GO:0032060 | bleb assembly(GO:0032060) |
| 2.4 | 7.1 | GO:1900073 | regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) |
| 2.4 | 7.1 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
| 2.4 | 16.5 | GO:0019720 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 2.3 | 14.1 | GO:0031999 | negative regulation of fatty acid beta-oxidation(GO:0031999) |
| 2.3 | 7.0 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 2.3 | 6.9 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 2.3 | 11.6 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 2.3 | 9.2 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 2.3 | 9.2 | GO:0001519 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 2.3 | 13.8 | GO:0052565 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 2.3 | 4.6 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 2.3 | 11.4 | GO:0010665 | regulation of cardiac muscle cell apoptotic process(GO:0010665) |
| 2.2 | 2.2 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 2.2 | 51.4 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 2.2 | 4.4 | GO:0070781 | response to biotin(GO:0070781) |
| 2.2 | 4.4 | GO:0042713 | sperm ejaculation(GO:0042713) |
| 2.2 | 17.7 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 2.2 | 24.1 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 2.2 | 26.2 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 2.2 | 4.4 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 2.2 | 43.3 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 2.2 | 6.5 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 2.2 | 19.4 | GO:0051410 | detoxification of nitrogen compound(GO:0051410) |
| 2.2 | 6.5 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
| 2.1 | 27.8 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 2.1 | 8.6 | GO:0038170 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 2.1 | 61.9 | GO:0015695 | organic cation transport(GO:0015695) |
| 2.1 | 4.3 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 2.1 | 4.2 | GO:0060605 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 2.1 | 8.5 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
| 2.1 | 4.2 | GO:0001575 | globoside metabolic process(GO:0001575) |
| 2.1 | 6.3 | GO:0090210 | regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212) |
| 2.1 | 2.1 | GO:0016078 | tRNA catabolic process(GO:0016078) |
| 2.1 | 8.4 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) |
| 2.1 | 6.3 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 2.1 | 20.8 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 2.1 | 2.1 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
| 2.1 | 18.5 | GO:0007507 | heart development(GO:0007507) |
| 2.1 | 6.2 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 2.1 | 2.1 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 2.0 | 8.2 | GO:0019046 | release from viral latency(GO:0019046) |
| 2.0 | 8.2 | GO:0015872 | dopamine transport(GO:0015872) |
| 2.0 | 24.5 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 2.0 | 12.2 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 2.0 | 4.1 | GO:1901877 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 2.0 | 34.6 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 2.0 | 2.0 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 2.0 | 54.7 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 2.0 | 6.1 | GO:1904823 | pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 2.0 | 6.1 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 2.0 | 6.0 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 2.0 | 10.1 | GO:0036102 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 2.0 | 4.0 | GO:0090024 | negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623) |
| 2.0 | 6.0 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) |
| 2.0 | 8.0 | GO:2000170 | negative regulation of gap junction assembly(GO:1903597) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
| 2.0 | 13.9 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 2.0 | 2.0 | GO:0015840 | urea transport(GO:0015840) |
| 2.0 | 7.9 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 2.0 | 3.9 | GO:0010165 | response to X-ray(GO:0010165) |
| 2.0 | 3.9 | GO:0001806 | type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) |
| 2.0 | 5.9 | GO:0043606 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 2.0 | 9.8 | GO:1904139 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141) |
| 2.0 | 7.8 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 2.0 | 3.9 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 1.9 | 5.8 | GO:0019605 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 1.9 | 3.9 | GO:0014002 | astrocyte development(GO:0014002) |
| 1.9 | 3.9 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 1.9 | 5.8 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) |
| 1.9 | 19.3 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 1.9 | 23.1 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 1.9 | 3.8 | GO:0051106 | positive regulation of DNA ligation(GO:0051106) |
| 1.9 | 3.8 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 1.9 | 11.4 | GO:0006857 | oligopeptide transport(GO:0006857) |
| 1.9 | 5.7 | GO:0045906 | negative regulation of vasoconstriction(GO:0045906) |
| 1.9 | 1.9 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
| 1.9 | 9.5 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 1.9 | 1.9 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 1.9 | 13.2 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 1.9 | 41.5 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 1.9 | 9.4 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.9 | 7.5 | GO:0072602 | interleukin-4 secretion(GO:0072602) |
| 1.9 | 5.6 | GO:0007538 | primary sex determination(GO:0007538) |
| 1.9 | 48.8 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 1.9 | 31.9 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 1.9 | 11.2 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 1.9 | 11.2 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 1.9 | 7.5 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 1.9 | 7.5 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 1.9 | 11.2 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 1.9 | 11.2 | GO:0051026 | chiasma assembly(GO:0051026) |
| 1.9 | 1.9 | GO:0009804 | coumarin metabolic process(GO:0009804) |
| 1.9 | 18.6 | GO:0014848 | urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848) |
| 1.9 | 7.4 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 1.8 | 9.2 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 1.8 | 38.6 | GO:0098743 | cell aggregation(GO:0098743) |