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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NKX2-4

Z-value: 0.87

Motif logo

Transcription factors associated with NKX2-4

Gene Symbol Gene ID Gene Info
ENSG00000125816.4 NK2 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-4hg19_v2_chr20_-_21378666_21378666-0.111.0e-01Click!

Activity profile of NKX2-4 motif

Sorted Z-values of NKX2-4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_49066811 10.35 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr10_-_28571015 7.60 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_-_225434538 7.02 ENST00000409096.1
cullin 3
chr1_-_153643442 6.46 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr7_-_96339132 6.39 ENST00000413065.1
split hand/foot malformation (ectrodactyly) type 1
chr7_-_93519471 6.34 ENST00000451238.1
tissue factor pathway inhibitor 2
chr7_+_116139424 6.18 ENST00000222693.4
caveolin 2
chr11_+_62439126 6.07 ENST00000377953.3
chromosome 11 open reading frame 83
chr7_+_75932863 6.04 ENST00000429938.1
heat shock 27kDa protein 1
chr17_-_38574169 5.91 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr12_+_8995832 5.75 ENST00000541459.1
alpha-2-macroglobulin-like 1
chr15_+_63334831 5.42 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
tropomyosin 1 (alpha)
chr17_-_15587602 5.38 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
tripartite motif containing 16
chr15_+_80364901 5.34 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
zinc finger, AN1-type domain 6
chr18_-_33702078 5.09 ENST00000586829.1
solute carrier family 39 (zinc transporter), member 6
chr3_-_32022733 5.03 ENST00000438237.2
ENST00000396556.2
oxysterol binding protein-like 10
chr6_+_83072923 4.98 ENST00000535040.1
trophoblast glycoprotein
chr6_+_83073334 4.89 ENST00000369750.3
trophoblast glycoprotein
chr8_-_74206673 4.79 ENST00000396465.1
ribosomal protein L7
chr15_-_63448973 4.68 ENST00000462430.1
ribosomal protein S27-like
chr11_+_118958689 4.21 ENST00000535253.1
ENST00000392841.1
hydroxymethylbilane synthase
chr17_-_5138099 4.19 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr4_-_103746683 4.16 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr10_+_81272287 3.98 ENST00000520547.2
eukaryotic translation initiation factor 5A-like 1
chr19_+_37998031 3.91 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
zinc finger protein 793
chr12_+_96252706 3.85 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr13_+_53216565 3.84 ENST00000357495.2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr7_-_96339167 3.71 ENST00000444799.1
ENST00000417009.1
ENST00000248566.2
split hand/foot malformation (ectrodactyly) type 1
chr15_-_34394008 3.64 ENST00000527822.1
ENST00000528949.1
ER membrane protein complex subunit 7
chr8_+_104310661 3.62 ENST00000522566.1
frizzled family receptor 6
chr7_+_134551583 3.61 ENST00000435928.1
caldesmon 1
chr14_+_56078695 3.55 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr11_+_60223312 3.54 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr7_-_54826869 3.52 ENST00000450622.1
Sec61 gamma subunit
chr11_+_60223225 3.40 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr14_+_62229075 3.35 ENST00000216294.4
small nuclear RNA activating complex, polypeptide 1, 43kDa
chr4_-_103747011 3.33 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr1_-_156721502 3.21 ENST00000357325.5
hepatoma-derived growth factor
chr14_-_23451467 3.20 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chr1_-_94147385 3.16 ENST00000260502.6
breast cancer anti-estrogen resistance 3
chr11_+_844406 3.16 ENST00000397404.1
tetraspanin 4
chr10_+_105005644 3.08 ENST00000441178.2
ribulose-5-phosphate-3-epimerase-like 1
chr4_-_103746924 3.07 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr4_+_169418195 3.06 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr19_-_41942344 3.05 ENST00000594660.1
ATP5S-like
chr8_-_49833978 3.04 ENST00000020945.1
snail family zinc finger 2
chr15_-_34394119 3.01 ENST00000256545.4
ER membrane protein complex subunit 7
chr12_-_57113333 2.99 ENST00000550920.1
nascent polypeptide-associated complex alpha subunit
chr2_-_188419200 2.95 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr11_-_85780853 2.91 ENST00000531930.1
ENST00000528398.1
phosphatidylinositol binding clathrin assembly protein
chr12_+_54422142 2.87 ENST00000243108.4
homeobox C6
chr5_-_98262240 2.81 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr5_-_34919094 2.79 ENST00000341754.4
RAD1 homolog (S. pombe)
chr11_-_14521379 2.71 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
coatomer protein complex, subunit beta 1
chr2_-_179315786 2.67 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr7_-_142232071 2.64 ENST00000390364.3
T cell receptor beta variable 10-1(gene/pseudogene)
chr14_-_23058063 2.58 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
defender against cell death 1
chr7_+_129932974 2.56 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
carboxypeptidase A4
chr8_+_97597148 2.56 ENST00000521590.1
syndecan 2
chr12_+_124069070 2.54 ENST00000262225.3
ENST00000438031.2
transmembrane emp24 domain trafficking protein 2
chr12_+_10658201 2.47 ENST00000322446.3
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr1_-_217250231 2.47 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr6_-_131277510 2.45 ENST00000525193.1
ENST00000527659.1
erythrocyte membrane protein band 4.1-like 2
chr3_-_107777208 2.41 ENST00000398258.3
CD47 molecule
chr10_+_22605374 2.38 ENST00000448361.1
COMM domain containing 3
chr4_+_39699664 2.37 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
ubiquitin-conjugating enzyme E2K
chrX_+_49294472 2.34 ENST00000361446.5
G antigen 12B
chr2_+_28615669 2.32 ENST00000379619.1
ENST00000264716.4
FOS-like antigen 2
chr9_+_131445928 2.26 ENST00000372692.4
SET nuclear oncogene
chr11_-_62439012 2.25 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
chromosome 11 open reading frame 48
chr14_+_64680854 2.25 ENST00000458046.2
spectrin repeat containing, nuclear envelope 2
chr9_+_90341024 2.24 ENST00000340342.6
ENST00000342020.5
cathepsin L
chr1_-_95391315 2.23 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr2_-_37899323 2.22 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr14_+_24702099 2.20 ENST00000420554.2
guanosine monophosphate reductase 2
chr11_+_65769946 2.14 ENST00000533166.1
barrier to autointegration factor 1
chr14_-_71067360 2.13 ENST00000554963.1
ENST00000430055.2
ENST00000440435.2
ENST00000256379.5
mediator complex subunit 6
chr7_+_29234375 2.12 ENST00000409350.1
ENST00000495789.2
ENST00000539389.1
chimerin 2
chr8_-_141774467 2.12 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr4_+_75480629 2.10 ENST00000380846.3
amphiregulin B
chr6_-_149969871 2.09 ENST00000335643.8
ENST00000444282.1
katanin p60 (ATPase containing) subunit A 1
chr2_-_219925189 2.08 ENST00000295731.6
indian hedgehog
chr2_+_161993412 2.07 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr10_+_22605304 2.05 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1 readthrough
COMM domain containing 3
chr9_-_127177703 2.05 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
proteasome (prosome, macropain) subunit, beta type, 7
chr12_-_56843161 2.02 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
timeless circadian clock
chr5_+_159436120 2.00 ENST00000522793.1
ENST00000231238.5
tetratricopeptide repeat domain 1
chr17_-_26684473 1.99 ENST00000540200.1
polymerase (DNA-directed), delta interacting protein 2
chr6_-_149969829 1.98 ENST00000367411.2
katanin p60 (ATPase containing) subunit A 1
chr2_-_27435125 1.98 ENST00000414408.1
ENST00000310574.3
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr11_+_65769550 1.92 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
barrier to autointegration factor 1
chrX_+_100075368 1.92 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr2_-_188419078 1.91 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_+_123011776 1.90 ENST00000450485.2
ENST00000333479.7
kinetochore associated 1
chr11_-_19223523 1.87 ENST00000265968.3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr2_-_176046391 1.85 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr17_+_66244071 1.82 ENST00000580548.1
ENST00000580753.1
ENST00000392720.2
ENST00000359783.4
ENST00000584837.1
ENST00000579724.1
ENST00000584494.1
ENST00000580837.1
archaelysin family metallopeptidase 2
chr12_-_57119106 1.79 ENST00000546392.1
nascent polypeptide-associated complex alpha subunit
chrX_-_119445306 1.74 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
transmembrane protein 255A
chr10_+_35484053 1.72 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
cAMP responsive element modulator
chrX_+_49178536 1.69 ENST00000442437.2
G antigen 12J
chr10_-_11574274 1.68 ENST00000277575.5
USP6 N-terminal like
chr7_+_120629653 1.66 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr11_-_85779971 1.66 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chr2_-_37544209 1.66 ENST00000234179.2
protein kinase D3
chr11_+_34642656 1.66 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr14_+_74353320 1.65 ENST00000540593.1
ENST00000555730.1
zinc finger protein 410
chr14_+_24701819 1.65 ENST00000560139.1
ENST00000559910.1
guanosine monophosphate reductase 2
chr8_-_141810634 1.63 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
protein tyrosine kinase 2
chrX_+_78200829 1.60 ENST00000544091.1
purinergic receptor P2Y, G-protein coupled, 10
chr1_-_70671216 1.56 ENST00000370952.3
leucine rich repeat containing 40
chr6_+_31674639 1.55 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr1_+_32042105 1.55 ENST00000457433.2
ENST00000441210.2
tubulointerstitial nephritis antigen-like 1
chr1_+_148560843 1.54 ENST00000442702.2
ENST00000369187.3
neuroblastoma breakpoint family, member 15
chr1_-_89458287 1.53 ENST00000370485.2
cysteine conjugate-beta lyase 2
chr1_+_15986364 1.51 ENST00000345034.1
regulatory solute carrier protein, family 1, member 1
chr14_+_24702127 1.51 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
guanosine monophosphate reductase 2
chr2_+_27435179 1.50 ENST00000606999.1
ENST00000405489.3
all-trans retinoic acid-induced differentiation factor
chr14_+_24702073 1.49 ENST00000399440.2
guanosine monophosphate reductase 2
chrX_-_133792480 1.47 ENST00000359237.4
placenta-specific 1
chr19_-_20748541 1.47 ENST00000427401.4
ENST00000594419.1
zinc finger protein 737
chr7_+_65552756 1.47 ENST00000450043.1
AC068533.7
chr10_+_21823079 1.46 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr2_+_37571845 1.45 ENST00000537448.1
glutaminyl-peptide cyclotransferase
chr9_-_86593238 1.44 ENST00000351839.3
heterogeneous nuclear ribonucleoprotein K
chrX_+_78200913 1.42 ENST00000171757.2
purinergic receptor P2Y, G-protein coupled, 10
chr5_-_176836577 1.39 ENST00000253496.3
coagulation factor XII (Hageman factor)
chr10_-_121296045 1.38 ENST00000392865.1
regulator of G-protein signaling 10
chr15_+_67430339 1.38 ENST00000439724.3
SMAD family member 3
chr8_+_7705398 1.33 ENST00000400125.2
ENST00000434307.2
ENST00000326558.5
ENST00000351436.4
ENST00000528033.1
sperm associated antigen 11A
chr8_-_7320974 1.29 ENST00000528943.1
ENST00000359758.5
ENST00000361111.2
ENST00000398462.2
ENST00000297498.2
ENST00000317900.5
sperm associated antigen 11B
chr12_+_58176525 1.28 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr2_-_220025548 1.28 ENST00000356853.5
nonhomologous end-joining factor 1
chr12_+_123237321 1.28 ENST00000280557.6
ENST00000455982.2
density-regulated protein
chr4_+_109541772 1.26 ENST00000506397.1
ENST00000394668.2
ribosomal protein L34
chr2_-_166651191 1.26 ENST00000392701.3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr11_+_64018955 1.25 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr14_+_24701628 1.24 ENST00000355299.4
ENST00000559836.1
guanosine monophosphate reductase 2
chr14_-_24701539 1.24 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr5_+_175298573 1.22 ENST00000512824.1
complexin 2
chr18_+_55816546 1.21 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr19_+_36235964 1.20 ENST00000587708.2
presenilin enhancer gamma secretase subunit
chr9_-_95298314 1.18 ENST00000344604.5
ENST00000375540.1
extracellular matrix protein 2, female organ and adipocyte specific
chr2_+_161993465 1.16 ENST00000457476.1
TRAF family member-associated NFKB activator
chr18_-_28622699 1.15 ENST00000360428.4
desmocollin 3
chr16_+_28943260 1.15 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19 molecule
chr11_+_57105991 1.14 ENST00000263314.2
purinergic receptor P2X, ligand-gated ion channel, 3
chr5_+_150040403 1.14 ENST00000517768.1
ENST00000297130.4
myozenin 3
chr19_+_58898627 1.14 ENST00000598098.1
ENST00000598495.1
ENST00000196551.3
ENST00000596046.1
ribosomal protein S5
chr2_-_170219079 1.14 ENST00000263816.3
low density lipoprotein receptor-related protein 2
chr7_-_86849025 1.13 ENST00000257637.3
transmembrane protein 243, mitochondrial
chr2_+_1417228 1.11 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
thyroid peroxidase
chr19_-_55669093 1.10 ENST00000344887.5
troponin I type 3 (cardiac)
chr6_+_153552455 1.10 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr12_+_50451331 1.09 ENST00000228468.4
acid-sensing (proton-gated) ion channel 1
chr19_-_49258606 1.09 ENST00000310160.3
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr17_-_63822563 1.08 ENST00000317442.8
centrosomal protein 112kDa
chr9_-_95166884 1.08 ENST00000375561.5
osteoglycin
chr18_+_56338618 1.07 ENST00000348428.3
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr3_-_88108192 1.07 ENST00000309534.6
CGG triplet repeat binding protein 1
chr2_-_175462456 1.05 ENST00000409891.1
ENST00000410117.1
WAS/WASL interacting protein family, member 1
chr18_-_28622774 1.04 ENST00000434452.1
desmocollin 3
chr10_+_21823243 1.03 ENST00000307729.7
ENST00000377091.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_-_197036364 1.02 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr9_-_95166841 1.02 ENST00000262551.4
osteoglycin
chr11_-_85780086 1.02 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
phosphatidylinositol binding clathrin assembly protein
chr4_-_155533787 1.02 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr11_+_76813886 1.01 ENST00000529803.1
olfactory marker protein
chr5_+_175298674 1.01 ENST00000514150.1
complexin 2
chr11_+_19138670 1.00 ENST00000446113.2
ENST00000399351.3
zinc finger, DHHC-type containing 13
chr11_-_19263145 0.99 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8
chr1_-_110155671 0.97 ENST00000351050.3
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr7_-_86849883 0.96 ENST00000433078.1
transmembrane protein 243, mitochondrial
chr3_-_126327398 0.96 ENST00000383572.2
thioredoxin reductase 3 neighbor
chr6_-_31088214 0.94 ENST00000376288.2
corneodesmosin
chr5_+_137203557 0.93 ENST00000515645.1
myotilin
chr14_+_22962898 0.92 ENST00000390492.1
T cell receptor alpha joining 45
chrX_-_124097620 0.91 ENST00000371130.3
ENST00000422452.2
teneurin transmembrane protein 1
chr11_+_12766583 0.90 ENST00000361985.2
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_+_144989309 0.90 ENST00000596396.1
Uncharacterized protein
chr3_-_88108212 0.89 ENST00000482016.1
CGG triplet repeat binding protein 1
chr14_+_22356029 0.88 ENST00000390437.2
T cell receptor alpha variable 12-2
chr16_+_81070792 0.88 ENST00000564241.1
ENST00000565237.1
ATM interactor
chr6_+_5261225 0.87 ENST00000324331.6
phenylalanyl-tRNA synthetase 2, mitochondrial
chr17_+_75277492 0.86 ENST00000427177.1
ENST00000591198.1
septin 9
chr16_+_3062457 0.86 ENST00000445369.2
claudin 9
chr8_+_22429205 0.85 ENST00000520207.1
sorbin and SH3 domain containing 3
chr10_-_69455873 0.85 ENST00000433211.2
catenin (cadherin-associated protein), alpha 3
chr1_+_152627927 0.84 ENST00000444515.1
ENST00000536536.1
long intergenic non-protein coding RNA 302
chr3_+_118905564 0.84 ENST00000460625.1
uroplakin 1B
chrX_-_74376108 0.83 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr1_+_161136180 0.83 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
protoporphyrinogen oxidase
chr1_+_13359819 0.83 ENST00000376168.1
PRAME family member 5
chr18_+_66465302 0.83 ENST00000360242.5
ENST00000358653.5
coiled-coil domain containing 102B
chr14_-_104028595 0.82 ENST00000337322.4
ENST00000445922.2
BCL2-associated athanogene 5
chr12_-_123011536 0.81 ENST00000331738.7
ENST00000354654.2
arginine/serine-rich coiled-coil 2
chrX_-_110655306 0.81 ENST00000371993.2
doublecortin
chr6_-_136610911 0.80 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCL2-associated transcription factor 1
chr12_-_123011476 0.79 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
arginine/serine-rich coiled-coil 2
chr13_+_49280951 0.77 ENST00000282018.3
cysteinyl leukotriene receptor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
1.7 10.3 GO:0006177 GMP biosynthetic process(GO:0006177)
1.5 6.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
1.1 7.6 GO:0071896 protein localization to adherens junction(GO:0071896)
1.0 6.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
1.0 3.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.9 3.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.8 3.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.8 5.6 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.7 2.8 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.7 1.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.7 4.1 GO:0051013 microtubule severing(GO:0051013)
0.7 5.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.6 2.5 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.6 4.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.6 5.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6 5.9 GO:0030263 resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263) embryonic cleavage(GO:0040016)
0.6 3.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.5 3.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 2.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.5 5.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.5 4.0 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5 1.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.5 1.9 GO:0035995 detection of muscle stretch(GO:0035995)
0.4 2.7 GO:0072719 cellular response to cisplatin(GO:0072719)
0.4 1.3 GO:0002188 translation reinitiation(GO:0002188)
0.4 3.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.4 4.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4 2.0 GO:0051182 coenzyme transport(GO:0051182)
0.4 5.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.4 2.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.4 2.6 GO:0008218 bioluminescence(GO:0008218)
0.4 1.4 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.4 1.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 4.1 GO:0015074 DNA integration(GO:0015074)
0.3 1.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 1.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 2.4 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.3 1.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 6.3 GO:0003334 keratinocyte development(GO:0003334)
0.3 6.9 GO:0006144 purine nucleobase metabolic process(GO:0006144) purine-containing compound salvage(GO:0043101)
0.3 0.8 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 1.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 5.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.7 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 5.0 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2 0.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 0.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 2.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 0.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 2.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 11.0 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.2 1.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 2.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 3.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 6.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.2 1.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 2.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2 1.1 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.2 2.2 GO:0071888 macrophage apoptotic process(GO:0071888)
0.1 0.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 1.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.8 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 2.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 2.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.4 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 1.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 2.4 GO:0008228 opsonization(GO:0008228)
0.1 3.3 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.9 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.4 GO:1902941 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.1 1.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 8.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 3.8 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 0.3 GO:0048867 stem cell fate determination(GO:0048867)
0.1 2.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.8 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.1 0.3 GO:0031269 pseudopodium assembly(GO:0031269)
0.1 1.9 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.8 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.5 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 1.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 1.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.6 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 2.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 1.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 1.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 1.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.8 GO:0015886 heme transport(GO:0015886)
0.1 4.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 6.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.2 GO:0031293 Notch receptor processing(GO:0007220) membrane protein intracellular domain proteolysis(GO:0031293)
0.1 5.9 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.0 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 1.1 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.1 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 2.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 2.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.7 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.8 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 1.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 2.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 2.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 3.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.9 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.8 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 3.0 GO:0007127 meiosis I(GO:0007127)
0.0 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 1.5 GO:0051051 negative regulation of transport(GO:0051051)
0.0 0.4 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 2.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.6 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0045636 regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636)
0.0 2.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.3 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.4 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 2.6 GO:0016573 histone acetylation(GO:0016573)
0.0 0.9 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 2.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.4 GO:0014002 astrocyte development(GO:0014002)
0.0 2.5 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 1.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.3 8.1 GO:1902560 GMP reductase complex(GO:1902560)
0.9 5.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.8 7.0 GO:0005827 polar microtubule(GO:0005827)
0.7 6.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.7 2.8 GO:0030896 checkpoint clamp complex(GO:0030896)
0.7 4.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.6 7.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 3.8 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.5 1.9 GO:1990423 RZZ complex(GO:1990423)
0.4 2.1 GO:0070847 core mediator complex(GO:0070847)
0.4 4.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 2.2 GO:0036021 endolysosome lumen(GO:0036021)
0.3 2.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3 5.4 GO:0032059 bleb(GO:0032059)
0.3 3.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 2.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 6.2 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.1 GO:0032449 CBM complex(GO:0032449)
0.2 7.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 2.7 GO:0070578 RISC-loading complex(GO:0070578)
0.2 1.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 2.5 GO:0008091 spectrin(GO:0008091)
0.2 1.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 2.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 12.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.9 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 2.0 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 6.0 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 3.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 3.1 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.8 GO:0032433 filopodium tip(GO:0032433)
0.1 4.5 GO:0002102 podosome(GO:0002102)
0.1 6.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 5.4 GO:0016605 PML body(GO:0016605)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 12.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.3 GO:0005840 ribosome(GO:0005840)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 6.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.1 GO:0031526 brush border membrane(GO:0031526)
0.1 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 2.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 4.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.8 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 7.1 GO:0030027 lamellipodium(GO:0030027)
0.0 3.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 10.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 3.1 GO:0005643 nuclear pore(GO:0005643)
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.6 GO:0005771 multivesicular body(GO:0005771)
0.0 4.1 GO:0000922 spindle pole(GO:0000922)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 9.3 GO:0010008 endosome membrane(GO:0010008)
0.0 3.8 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 3.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0000791 euchromatin(GO:0000791)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.9 GO:0030018 Z disc(GO:0030018)
0.0 1.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.0 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 8.6 GO:0009986 cell surface(GO:0009986)
0.0 0.8 GO:0016234 inclusion body(GO:0016234)
0.0 0.9 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 2.6 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
2.0 6.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
2.0 5.9 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.8 5.4 GO:0032089 NACHT domain binding(GO:0032089)
1.8 7.0 GO:0031208 POZ domain binding(GO:0031208)
1.3 8.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.7 4.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.7 2.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.6 3.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.5 1.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.5 5.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 2.8 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 1.2 GO:0070052 collagen V binding(GO:0070052)
0.4 1.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.4 2.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.4 3.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 3.1 GO:0031433 telethonin binding(GO:0031433)
0.3 2.7 GO:0070883 pre-miRNA binding(GO:0070883)
0.3 1.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 4.7 GO:0008494 translation activator activity(GO:0008494)
0.3 5.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 2.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 3.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 2.5 GO:0042731 PH domain binding(GO:0042731)
0.2 2.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 11.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 6.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 3.7 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 3.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 5.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 4.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.1 GO:0005113 patched binding(GO:0005113)
0.2 1.0 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 0.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 3.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 2.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 0.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 3.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 15.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0030172 troponin C binding(GO:0030172)
0.1 2.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.4 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 11.7 GO:0032947 protein complex scaffold(GO:0032947)
0.1 5.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 5.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.1 6.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.6 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 3.5 GO:0019894 kinesin binding(GO:0019894)
0.1 0.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.7 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.8 GO:0089720 caspase binding(GO:0089720)
0.1 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.0 GO:0070330 aromatase activity(GO:0070330)
0.1 0.9 GO:0017166 vinculin binding(GO:0017166)
0.1 3.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.3 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 0.4 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 4.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 8.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 2.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 6.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 3.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 3.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0043425 bHLH transcription factor binding(GO:0043425)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 7.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 8.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 8.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 5.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 6.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 7.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.5 PID ATR PATHWAY ATR signaling pathway
0.1 3.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 7.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 9.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.5 4.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 5.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 6.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 2.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 10.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 3.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 7.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 3.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 5.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 3.5 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.2 3.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 9.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.9 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.1 1.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 3.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 8.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 3.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 1.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.8 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 2.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.9 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 5.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 7.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 3.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 3.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation