Project

averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for NKX3-2

Z-value: 1.14

Motif logo

Transcription factors associated with NKX3-2

Gene Symbol Gene ID Gene Info
ENSG00000109705.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-2hg19_v2_chr4_-_13546632_135466740.291.8e-05Click!

Activity profile of NKX3-2 motif

Sorted Z-values of NKX3-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_38420783 17.68 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr1_-_156399184 17.02 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chr12_-_54978086 16.29 ENST00000553113.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chrX_+_38420623 15.37 ENST00000378482.2
tetraspanin 7
chr8_-_27115931 14.22 ENST00000523048.1
stathmin-like 4
chr2_+_17721920 13.52 ENST00000295156.4
visinin-like 1
chr17_+_38083977 12.52 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr8_-_27115903 12.30 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr1_+_160097462 11.10 ENST00000447527.1
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr19_+_16999654 10.96 ENST00000248076.3
coagulation factor II (thrombin) receptor-like 3
chr5_-_149792295 10.21 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74 molecule, major histocompatibility complex, class II invariant chain
chr19_-_3028354 10.18 ENST00000586422.1
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr2_-_208489707 9.46 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
methyltransferase like 21A
chr4_+_156588249 8.84 ENST00000393832.3
guanylate cyclase 1, soluble, alpha 3
chr19_-_6720686 8.58 ENST00000245907.6
complement component 3
chr5_+_156696362 8.55 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr14_-_60337684 7.95 ENST00000267484.5
reticulon 1
chr8_-_90769422 7.77 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
chr22_+_38453207 7.72 ENST00000404072.3
ENST00000424694.1
protein interacting with PRKCA 1
chr2_-_175869936 7.58 ENST00000409900.3
chimerin 1
chr6_-_32557610 7.48 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr19_-_17185848 7.42 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chrX_+_48660287 7.39 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
histone deacetylase 6
chr7_-_99573677 7.30 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr2_-_175870085 7.24 ENST00000409156.3
chimerin 1
chr11_-_111175739 7.23 ENST00000532918.1
colorectal cancer associated 1
chr4_+_156587979 7.07 ENST00000511507.1
guanylate cyclase 1, soluble, alpha 3
chr2_+_25016282 6.97 ENST00000260662.1
centromere protein O
chr2_+_220379052 6.92 ENST00000347842.3
ENST00000358078.4
acid-sensing (proton-gated) ion channel family member 4
chr15_+_99645277 6.70 ENST00000336292.6
ENST00000328642.7
synemin, intermediate filament protein
chrX_+_44732757 6.67 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
lysine (K)-specific demethylase 6A
chr10_-_98031265 6.62 ENST00000224337.5
ENST00000371176.2
B-cell linker
chrX_-_49965663 6.60 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
A kinase (PRKA) anchor protein 4
chr10_-_98031310 6.53 ENST00000427367.2
ENST00000413476.2
B-cell linker
chr3_-_149688502 6.45 ENST00000481767.1
ENST00000475518.1
profilin 2
chr1_-_173793458 6.40 ENST00000356198.2
centromere protein L
chrX_-_71526813 6.37 ENST00000246139.5
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr14_-_106963409 6.32 ENST00000390621.2
immunoglobulin heavy variable 1-45
chr11_-_22851367 6.11 ENST00000354193.4
small VCP/p97-interacting protein
chr14_-_74551172 5.96 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr5_+_78407602 5.91 ENST00000274353.5
ENST00000524080.1
betaine--homocysteine S-methyltransferase
chr16_-_21289627 5.91 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr4_+_156680518 5.87 ENST00000513437.1
guanylate cyclase 1, soluble, beta 3
chr3_-_49907323 5.86 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CaM kinase-like vesicle-associated
chr5_+_156712372 5.69 ENST00000541131.1
cytoplasmic FMR1 interacting protein 2
chr17_-_19771216 5.68 ENST00000395544.4
unc-51 like autophagy activating kinase 2
chr10_+_101088836 5.57 ENST00000356713.4
cyclin M1
chr14_-_90798418 5.56 ENST00000354366.3
NRDE-2, necessary for RNA interference, domain containing
chr22_+_38453378 5.48 ENST00000437453.1
ENST00000356976.3
protein interacting with PRKCA 1
chr10_-_75571566 5.45 ENST00000299641.4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr4_-_141348789 5.41 ENST00000414773.1
calmegin
chr10_+_7745303 5.33 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_101089107 5.31 ENST00000446890.1
ENST00000370528.3
cyclin M1
chr19_+_36266417 5.24 ENST00000378944.5
ENST00000007510.4
Rho GTPase activating protein 33
chr2_+_25015968 5.23 ENST00000380834.2
ENST00000473706.1
centromere protein O
chr4_+_156588115 5.21 ENST00000455639.2
guanylate cyclase 1, soluble, alpha 3
chr4_+_113970772 5.19 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr15_+_81475047 5.14 ENST00000559388.1
interleukin 16
chr10_-_99531709 4.89 ENST00000266066.3
secreted frizzled-related protein 5
chr7_+_129906660 4.87 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr10_-_75571341 4.84 ENST00000309979.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr10_+_7745232 4.84 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr17_-_617949 4.75 ENST00000401468.3
ENST00000574029.1
ENST00000291074.5
ENST00000571805.1
ENST00000437048.2
ENST00000446250.2
vacuolar protein sorting 53 homolog (S. cerevisiae)
chr20_+_42839722 4.73 ENST00000442383.1
ENST00000435163.1
OSER1 antisense RNA 1 (head to head)
chr17_-_74137374 4.70 ENST00000322957.6
forkhead box J1
chrX_+_76709648 4.67 ENST00000439435.1
fibroblast growth factor 16
chr17_+_45810594 4.66 ENST00000177694.1
T-box 21
chr11_-_119993979 4.61 ENST00000524816.3
ENST00000525327.1
tripartite motif containing 29
chr5_-_160279207 4.46 ENST00000327245.5
ATPase, class V, type 10B
chr19_-_5680202 4.29 ENST00000590389.1
chromosome 19 open reading frame 70
chr4_+_156588350 4.24 ENST00000296518.7
guanylate cyclase 1, soluble, alpha 3
chr8_+_86376081 4.23 ENST00000285379.5
carbonic anhydrase II
chr2_+_79347577 4.21 ENST00000233735.1
regenerating islet-derived 1 alpha
chr17_+_58755184 4.19 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr7_+_29237354 4.15 ENST00000546235.1
chimerin 2
chr1_-_153013588 4.13 ENST00000360379.3
small proline-rich protein 2D
chr5_+_40909354 4.11 ENST00000313164.9
complement component 7
chr3_+_38537960 4.08 ENST00000453767.1
endo/exonuclease (5'-3'), endonuclease G-like
chr19_-_6767516 4.07 ENST00000245908.6
SH2 domain containing 3A
chr11_+_2421718 4.06 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
tumor suppressing subtransferable candidate 4
chr11_-_102401469 4.05 ENST00000260227.4
matrix metallopeptidase 7 (matrilysin, uterine)
chr1_+_205473720 4.01 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr1_+_152974218 3.99 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
small proline-rich protein 3
chrX_+_100333709 3.94 ENST00000372930.4
transmembrane protein 35
chr5_-_115872142 3.89 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_21927736 3.89 ENST00000240662.2
potassium inwardly-rectifying channel, subfamily J, member 8
chr3_-_128712955 3.88 ENST00000265068.5
KIAA1257
chr17_-_46507537 3.86 ENST00000336915.6
src kinase associated phosphoprotein 1
chr3_+_38537763 3.84 ENST00000287675.5
ENST00000358249.2
ENST00000422077.2
endo/exonuclease (5'-3'), endonuclease G-like
chr12_+_57984965 3.83 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr7_+_16828866 3.79 ENST00000597084.1
Uncharacterized protein
chr15_+_75639951 3.73 ENST00000564784.1
ENST00000569035.1
nei endonuclease VIII-like 1 (E. coli)
chr10_-_95360983 3.73 ENST00000371464.3
retinol binding protein 4, plasma
chr3_+_111697843 3.69 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
abhydrolase domain containing 10
chr1_+_151739131 3.68 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr4_-_11430221 3.61 ENST00000514690.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr3_-_50541028 3.61 ENST00000266039.3
ENST00000435965.1
ENST00000395083.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr3_-_149688896 3.59 ENST00000239940.7
profilin 2
chr7_-_99573640 3.55 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr14_-_23770683 3.54 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
protein phosphatase 1, regulatory subunit 3E
chr6_-_136788001 3.52 ENST00000544465.1
microtubule-associated protein 7
chr1_-_182573514 3.51 ENST00000367558.5
regulator of G-protein signaling 16
chr3_+_125694347 3.46 ENST00000505382.1
ENST00000511082.1
rhophilin associated tail protein 1B
chr10_-_115933942 3.41 ENST00000369285.3
ENST00000369287.3
ENST00000369286.1
chromosome 10 open reading frame 118
chr17_-_9929581 3.38 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chrX_+_51928002 3.38 ENST00000375626.3
melanoma antigen family D, 4
chrX_+_153665248 3.36 ENST00000447750.2
GDP dissociation inhibitor 1
chr12_+_6961279 3.35 ENST00000229268.8
ENST00000389231.5
ENST00000542087.1
ubiquitin specific peptidase 5 (isopeptidase T)
chr19_+_48867652 3.31 ENST00000344846.2
synaptogyrin 4
chr11_-_1036706 3.29 ENST00000421673.2
mucin 6, oligomeric mucus/gel-forming
chr5_+_79331164 3.27 ENST00000350881.2
thrombospondin 4
chr7_-_135412925 3.23 ENST00000354042.4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr16_+_57406368 3.23 ENST00000006053.6
ENST00000563383.1
chemokine (C-X3-C motif) ligand 1
chr1_-_216978709 3.19 ENST00000360012.3
estrogen-related receptor gamma
chr6_-_11382478 3.19 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
neural precursor cell expressed, developmentally down-regulated 9
chr3_+_52454971 3.18 ENST00000465863.1
PHD finger protein 7
chr6_+_42928485 3.17 ENST00000372808.3
glycine N-methyltransferase
chr11_-_64511789 3.08 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_+_36545833 3.05 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WD repeat domain 62
chr9_+_34458771 3.04 ENST00000437363.1
ENST00000242317.4
dynein, axonemal, intermediate chain 1
chr6_-_150039249 3.02 ENST00000543571.1
large tumor suppressor kinase 1
chr1_+_173793777 3.01 ENST00000239457.5
aspartyl-tRNA synthetase 2, mitochondrial
chr14_-_24711470 3.01 ENST00000559969.1
TERF1 (TRF1)-interacting nuclear factor 2
chr9_-_131644202 2.98 ENST00000320665.6
ENST00000436267.2
cysteine conjugate-beta lyase, cytoplasmic
chr1_+_22307592 2.93 ENST00000400277.2
chymotrypsin-like elastase family, member 3B
chr18_-_6414884 2.92 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
l(3)mbt-like 4 (Drosophila)
chr19_-_36297348 2.91 ENST00000589835.1
proline dehydrogenase (oxidase) 2
chr19_-_44809121 2.91 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
zinc finger protein 235
chr6_+_26156551 2.88 ENST00000304218.3
histone cluster 1, H1e
chr12_-_120765565 2.86 ENST00000423423.3
ENST00000308366.4
phospholipase A2, group IB (pancreas)
chr3_-_185216766 2.84 ENST00000296254.3
transmembrane protein 41A
chr11_-_207221 2.82 ENST00000486280.1
ENST00000332865.6
ENST00000529614.2
ENST00000325147.9
ENST00000410108.1
ENST00000382762.3
Bet1 golgi vesicular membrane trafficking protein-like
chr11_-_63381823 2.82 ENST00000323646.5
phospholipase A2, group XVI
chr1_+_66258846 2.80 ENST00000341517.4
phosphodiesterase 4B, cAMP-specific
chr12_+_56473910 2.77 ENST00000411731.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_+_60280458 2.76 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr1_+_158223923 2.73 ENST00000289429.5
CD1a molecule
chr11_+_128563652 2.73 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr11_-_119993734 2.72 ENST00000533302.1
tripartite motif containing 29
chr16_+_83986827 2.71 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr22_-_21356375 2.69 ENST00000215742.4
ENST00000399133.2
THAP domain containing 7
chr4_+_62067860 2.68 ENST00000514591.1
latrophilin 3
chr9_-_23821842 2.68 ENST00000544538.1
ELAV like neuron-specific RNA binding protein 2
chr11_-_64512469 2.68 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_+_57999079 2.67 ENST00000426954.2
ENST00000354197.4
ENST00000523882.1
ENST00000520540.1
ENST00000519310.1
ENST00000442920.2
ENST00000523312.1
ENST00000424930.2
zinc finger protein 419
chr12_+_50794730 2.64 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
La ribonucleoprotein domain family, member 4
chr10_-_17171817 2.63 ENST00000377833.4
cubilin (intrinsic factor-cobalamin receptor)
chr11_-_118047376 2.63 ENST00000278947.5
sodium channel, voltage-gated, type II, beta subunit
chr15_+_42694573 2.62 ENST00000397200.4
ENST00000569827.1
calpain 3, (p94)
chr12_-_10151773 2.62 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr19_+_57999101 2.60 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
zinc finger protein 419
chr4_+_75023816 2.55 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr12_-_122296755 2.53 ENST00000289004.4
4-hydroxyphenylpyruvate dioxygenase
chr12_-_54019755 2.53 ENST00000588078.1
ENST00000551480.2
ENST00000548118.2
ENST00000456903.4
ENST00000591834.1
activating transcription factor 7
Uncharacterized protein
chr11_-_128737163 2.51 ENST00000324003.3
ENST00000392665.2
potassium inwardly-rectifying channel, subfamily J, member 1
chrX_+_18725758 2.46 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr2_-_24270217 2.46 ENST00000295148.4
ENST00000406895.3
chromosome 2 open reading frame 44
chr14_-_98444386 2.46 ENST00000556462.1
ENST00000556138.1
chromosome 14 open reading frame 64
chr4_+_144303093 2.46 ENST00000505913.1
GRB2-associated binding protein 1
chr10_+_5005445 2.42 ENST00000380872.4
aldo-keto reductase family 1, member C1
chr16_-_2318055 2.42 ENST00000561518.1
ENST00000561718.1
ENST00000567147.1
ENST00000562690.1
ENST00000569598.2
RNA binding protein S1, serine-rich domain
chr1_+_210001309 2.41 ENST00000491415.2
digestive organ expansion factor homolog (zebrafish)
chr14_+_21467414 2.38 ENST00000554422.1
ENST00000298681.4
solute carrier family 39 (zinc transporter), member 2
chr10_+_18629628 2.38 ENST00000377329.4
calcium channel, voltage-dependent, beta 2 subunit
chr20_+_53092123 2.36 ENST00000262593.5
docking protein 5
chr16_+_55690002 2.36 ENST00000414754.3
solute carrier family 6 (neurotransmitter transporter), member 2
chr14_-_106830057 2.34 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr11_-_128737259 2.30 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
potassium inwardly-rectifying channel, subfamily J, member 1
chr19_+_16435625 2.28 ENST00000248071.5
ENST00000592003.1
Kruppel-like factor 2
chr16_-_27561209 2.27 ENST00000356183.4
ENST00000561623.1
general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr20_+_53092232 2.26 ENST00000395939.1
docking protein 5
chr5_-_59481406 2.23 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr5_+_56111361 2.21 ENST00000399503.3
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr12_+_4382917 2.20 ENST00000261254.3
cyclin D2
chr4_-_141348999 2.19 ENST00000325617.5
calmegin
chr9_+_131062367 2.18 ENST00000601297.1
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr1_+_36690011 2.17 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
thyroid hormone receptor associated protein 3
chr7_+_130020180 2.13 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
carboxypeptidase A1 (pancreatic)
chr15_-_88799661 2.13 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr5_+_140810132 2.12 ENST00000252085.3
protocadherin gamma subfamily A, 12
chr18_+_72167096 2.12 ENST00000324301.8
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr4_+_144258021 2.12 ENST00000262994.4
GRB2-associated binding protein 1
chr1_+_119957554 2.12 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr1_-_202858227 2.11 ENST00000367262.3
RAB interacting factor
chr6_-_32731243 2.09 ENST00000427449.1
ENST00000411527.1
major histocompatibility complex, class II, DQ beta 2
chr11_+_67250490 2.08 ENST00000528641.2
ENST00000279146.3
aryl hydrocarbon receptor interacting protein
chr2_-_182545603 2.06 ENST00000295108.3
neuronal differentiation 1
chr7_+_110731062 2.05 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr14_-_21567009 2.04 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
zinc finger protein 219
chr19_-_51920952 2.03 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
sialic acid binding Ig-like lectin 10
chr10_+_35415719 1.99 ENST00000474362.1
ENST00000374721.3
cAMP responsive element modulator
chr10_-_47173994 1.99 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr2_+_102927962 1.97 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr11_-_59633951 1.96 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr6_-_32784687 1.96 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr20_+_2821340 1.96 ENST00000380445.3
ENST00000380469.3
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr4_-_109087872 1.95 ENST00000510624.1
lymphoid enhancer-binding factor 1
chr10_-_7708918 1.94 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr7_-_79082867 1.94 ENST00000419488.1
ENST00000354212.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_+_68071389 1.94 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 25.4 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
2.9 8.6 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
2.5 7.4 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
2.2 6.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
2.2 11.1 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
2.0 10.2 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.0 6.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.0 5.9 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
1.9 13.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.8 14.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.7 5.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.7 6.7 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
1.6 4.9 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.6 4.7 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
1.5 7.5 GO:0002399 MHC class II protein complex assembly(GO:0002399)
1.5 6.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
1.4 4.2 GO:0042938 dipeptide transport(GO:0042938)
1.4 11.0 GO:0060155 platelet dense granule organization(GO:0060155)
1.3 2.6 GO:0030220 platelet formation(GO:0030220)
1.2 4.9 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
1.1 3.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.1 6.4 GO:0071105 response to interleukin-11(GO:0071105)
1.0 5.9 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
1.0 1.9 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
1.0 4.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.9 9.5 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.9 4.5 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.9 10.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.8 0.8 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.8 10.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.8 5.7 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.8 2.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.7 3.7 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.7 3.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.7 3.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.7 2.9 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.7 2.1 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.7 4.7 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.7 2.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.6 1.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.6 3.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.6 3.0 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.6 4.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.5 5.9 GO:0006554 lysine catabolic process(GO:0006554)
0.5 5.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.5 2.6 GO:0071895 odontoblast differentiation(GO:0071895)
0.5 1.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.5 2.5 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.5 3.0 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.5 3.0 GO:0046684 response to pyrethroid(GO:0046684)
0.5 1.5 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.5 1.5 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.5 2.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 2.9 GO:0016584 nucleosome positioning(GO:0016584)
0.5 1.4 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.5 3.7 GO:0016139 glycoside catabolic process(GO:0016139)
0.5 4.6 GO:0015889 cobalamin transport(GO:0015889)
0.5 15.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.5 14.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 0.9 GO:0048867 stem cell fate determination(GO:0048867)
0.4 2.6 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 3.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.4 5.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 19.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.4 2.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 2.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.4 2.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 0.8 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.4 1.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.4 6.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.4 2.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.4 2.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 9.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 3.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 1.0 GO:0061009 midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164) common bile duct development(GO:0061009)
0.3 13.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.3 2.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 2.1 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 8.4 GO:0044458 motile cilium assembly(GO:0044458)
0.3 2.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 2.3 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.3 1.9 GO:0006021 inositol biosynthetic process(GO:0006021)
0.3 3.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 5.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 4.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 3.5 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.3 3.2 GO:0008272 sulfate transport(GO:0008272)
0.3 12.4 GO:0010107 potassium ion import(GO:0010107)
0.3 3.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 1.4 GO:0044026 DNA hypermethylation(GO:0044026)
0.2 5.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 2.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 3.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 1.2 GO:0086053 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2 2.0 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.2 5.7 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.2 1.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.2 0.9 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.2 0.6 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.2 10.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.2 0.6 GO:1900371 regulation of cyclic nucleotide metabolic process(GO:0030799) positive regulation of cyclic nucleotide metabolic process(GO:0030801) regulation of cyclic nucleotide biosynthetic process(GO:0030802) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) regulation of nucleotide biosynthetic process(GO:0030808) positive regulation of nucleotide biosynthetic process(GO:0030810) regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of purine nucleotide biosynthetic process(GO:1900371) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.2 23.5 GO:0005977 glycogen metabolic process(GO:0005977)
0.2 12.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 7.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 1.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 1.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838) negative regulation of keratinocyte differentiation(GO:0045617)
0.2 4.3 GO:0016246 RNA interference(GO:0016246)
0.2 1.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 1.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 1.5 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 10.5 GO:0018149 peptide cross-linking(GO:0018149)
0.2 4.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.2 3.9 GO:0015874 norepinephrine transport(GO:0015874)
0.2 1.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 1.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 2.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 1.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.2 0.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 2.7 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.4 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.9 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.1 2.1 GO:0006705 androgen biosynthetic process(GO:0006702) mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.9 GO:0010001 glial cell differentiation(GO:0010001)
0.1 1.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 8.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.9 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 0.8 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 7.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 1.4 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.1 0.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 2.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 4.7 GO:0032456 endocytic recycling(GO:0032456)
0.1 2.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 2.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 2.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 3.3 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 2.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 13.5 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.6 GO:0043486 histone exchange(GO:0043486)
0.1 5.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 3.0 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.1 2.8 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 1.6 GO:0031297 replication fork processing(GO:0031297)
0.1 1.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.8 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 2.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.6 GO:0015825 L-serine transport(GO:0015825)
0.1 1.3 GO:0010876 lipid localization(GO:0010876)
0.1 1.3 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 5.7 GO:0044764 multi-organism cellular process(GO:0044764)
0.0 4.4 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 2.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0034344 detection of virus(GO:0009597) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 1.2 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 3.5 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 2.8 GO:0072676 lymphocyte migration(GO:0072676)
0.0 1.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.0 1.2 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 3.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.7 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 1.1 GO:0033198 response to ATP(GO:0033198)
0.0 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 2.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 3.5 GO:0007586 digestion(GO:0007586)
0.0 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.7 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 1.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 2.9 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 4.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 5.4 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 1.1 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 3.9 GO:0072659 protein localization to plasma membrane(GO:0072659)
0.0 0.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.7 GO:0006959 humoral immune response(GO:0006959)
0.0 3.2 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.9 GO:0060349 bone morphogenesis(GO:0060349)
0.0 1.5 GO:0000910 cytokinesis(GO:0000910)
0.0 2.7 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 2.4 GO:0007254 JNK cascade(GO:0007254)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0010830 regulation of myotube differentiation(GO:0010830)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.5 10.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.3 3.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.3 31.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.2 4.7 GO:1990745 EARP complex(GO:1990745)
1.2 1.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.9 8.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.8 7.4 GO:0070652 HAUS complex(GO:0070652)
0.8 1.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.7 2.8 GO:0070695 FHF complex(GO:0070695)
0.6 12.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 6.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.6 3.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.6 6.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.6 11.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 2.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.5 1.8 GO:0097224 sperm connecting piece(GO:0097224)
0.5 4.1 GO:0005579 membrane attack complex(GO:0005579)
0.4 2.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.4 1.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 3.5 GO:0016013 syntrophin complex(GO:0016013)
0.4 3.0 GO:0036157 outer dynein arm(GO:0036157)
0.4 20.6 GO:0016235 aggresome(GO:0016235)
0.4 2.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 2.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 1.9 GO:1990130 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 1.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.3 0.9 GO:0044305 calyx of Held(GO:0044305)
0.3 0.9 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.3 2.4 GO:0061574 ASAP complex(GO:0061574)
0.3 1.5 GO:1990769 proximal neuron projection(GO:1990769)
0.2 2.5 GO:0097486 multivesicular body lumen(GO:0097486)
0.2 5.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 2.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 2.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 2.0 GO:0030897 HOPS complex(GO:0030897)
0.2 2.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 11.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 8.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 4.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 2.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 2.8 GO:0005922 connexon complex(GO:0005922)
0.1 6.9 GO:0001533 cornified envelope(GO:0001533)
0.1 22.0 GO:0072562 blood microparticle(GO:0072562)
0.1 10.0 GO:0043195 terminal bouton(GO:0043195)
0.1 6.4 GO:0030315 T-tubule(GO:0030315)
0.1 3.9 GO:0042101 T cell receptor complex(GO:0042101)
0.1 23.3 GO:0030426 growth cone(GO:0030426)
0.1 1.4 GO:0000243 commitment complex(GO:0000243)
0.1 5.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 2.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.4 GO:0032040 small-subunit processome(GO:0032040)
0.1 2.8 GO:0031201 SNARE complex(GO:0031201)
0.1 8.6 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.1 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.1 GO:0001741 XY body(GO:0001741)
0.1 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 4.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 2.5 GO:0034399 nuclear periphery(GO:0034399)
0.1 10.1 GO:0000922 spindle pole(GO:0000922)
0.1 4.2 GO:0005902 microvillus(GO:0005902)
0.1 1.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.9 GO:0031904 endosome lumen(GO:0031904)
0.0 4.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 4.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.5 GO:0031514 motile cilium(GO:0031514)
0.0 3.5 GO:0005875 microtubule associated complex(GO:0005875)
0.0 2.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.8 GO:0005776 autophagosome(GO:0005776)
0.0 2.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.8 GO:0005901 caveola(GO:0005901)
0.0 43.4 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0000791 euchromatin(GO:0000791)
0.0 1.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 39.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 9.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 4.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 1.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
2.2 6.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
2.0 10.2 GO:0042289 MHC class II protein binding(GO:0042289)
2.0 16.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
2.0 12.1 GO:0015057 thrombin receptor activity(GO:0015057)
2.0 5.9 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
1.8 7.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.6 13.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.6 9.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.5 5.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
1.4 4.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
1.3 3.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.3 31.9 GO:0004383 guanylate cyclase activity(GO:0004383)
1.0 4.9 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.8 2.5 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.8 11.1 GO:1990239 steroid hormone binding(GO:1990239)
0.8 2.4 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.8 2.3 GO:0000995 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.7 3.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.7 2.9 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.7 2.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.7 2.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.7 13.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7 2.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.7 0.7 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.6 1.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 1.9 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.6 2.4 GO:0047718 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.6 3.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.6 2.8 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.6 1.7 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.5 4.2 GO:0004064 arylesterase activity(GO:0004064)
0.5 2.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5 1.5 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.5 1.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.5 2.9 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.5 1.4 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.5 6.4 GO:0050693 LBD domain binding(GO:0050693)
0.4 6.7 GO:0019215 intermediate filament binding(GO:0019215)
0.4 7.9 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.4 4.6 GO:0031419 cobalamin binding(GO:0031419)
0.4 7.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.4 11.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.4 3.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.4 2.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 6.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 3.5 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.3 1.4 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.3 5.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 1.2 GO:0043559 insulin binding(GO:0043559)
0.3 1.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 2.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 13.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 2.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 2.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 0.8 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.3 2.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 3.7 GO:0016918 retinal binding(GO:0016918)
0.2 1.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 5.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 2.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 6.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 7.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.2 2.0 GO:0004969 histamine receptor activity(GO:0004969)
0.2 3.2 GO:0016594 glycine binding(GO:0016594)
0.2 3.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 3.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 3.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 2.8 GO:0038132 neuregulin binding(GO:0038132)
0.2 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 7.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 2.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 22.5 GO:0051117 ATPase binding(GO:0051117)
0.2 2.6 GO:0031432 titin binding(GO:0031432)
0.2 4.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.9 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 1.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 17.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 5.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 2.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 6.9 GO:0005272 sodium channel activity(GO:0005272)
0.2 1.6 GO:0005243 gap junction channel activity(GO:0005243)
0.2 0.9 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296) exodeoxyribonuclease III activity(GO:0008853)
0.2 0.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.8 GO:0032027 myosin light chain binding(GO:0032027)
0.2 8.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 3.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 4.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 4.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 3.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 8.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 2.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 3.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 12.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.8 GO:0019863 IgE binding(GO:0019863)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 5.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.7 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 20.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 12.2 GO:0008083 growth factor activity(GO:0008083)
0.1 3.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 2.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.1 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 2.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 3.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 4.1 GO:0005125 cytokine activity(GO:0005125)
0.0 3.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.9 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)
0.0 2.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0019956 chemokine binding(GO:0019956)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 15.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.4 8.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.4 4.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 14.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 14.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 13.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 14.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 7.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 5.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 7.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 4.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 13.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 7.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 3.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 5.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 12.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 PID SHP2 PATHWAY SHP2 signaling
0.0 1.5 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 7.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 32.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.5 13.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.4 8.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.4 13.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 13.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.4 11.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.4 5.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 7.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 13.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 15.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 4.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 3.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 19.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 5.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.2 5.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 6.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 10.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 2.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 5.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 8.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.3 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.2 1.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 10.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 3.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 7.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 2.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 5.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 4.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 12.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 17.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 2.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 2.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 10.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis