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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR1I2

Z-value: 1.29

Motif logo

Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
ENSG00000144852.12 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119499331_119499331,
hg19_v2_chr3_+_119501557_119501557
0.306.1e-06Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91576429 46.20 ENST00000552145.1
ENST00000546745.1
decorin
chr11_+_117073850 24.79 ENST00000529622.1
transgelin
chr12_-_91576561 19.83 ENST00000547568.2
ENST00000552962.1
decorin
chr12_-_91576750 15.24 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
decorin
chr3_+_153839149 13.28 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr11_+_62439126 13.15 ENST00000377953.3
chromosome 11 open reading frame 83
chr19_+_42817527 12.41 ENST00000598766.1
transmembrane protein 145
chr3_-_196065248 11.63 ENST00000446879.1
ENST00000273695.3
transmembrane 4 L six family member 19
chr11_-_111783595 11.46 ENST00000528628.1
crystallin, alpha B
chr16_-_4292071 11.24 ENST00000399609.3
sarcalumenin
chr11_-_111794446 11.01 ENST00000527950.1
crystallin, alpha B
chr3_-_114343039 10.86 ENST00000481632.1
zinc finger and BTB domain containing 20
chr2_+_111490161 10.75 ENST00000340561.4
acyl-CoA oxidase-like
chrX_+_135279179 10.73 ENST00000370676.3
four and a half LIM domains 1
chrX_+_135278908 10.39 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr15_+_96876340 9.89 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr5_+_149569520 9.60 ENST00000230671.2
ENST00000524041.1
solute carrier family 6 (neurotransmitter transporter), member 7
chr15_+_39873268 9.58 ENST00000397591.2
ENST00000260356.5
thrombospondin 1
chr13_-_110959478 9.39 ENST00000543140.1
ENST00000375820.4
collagen, type IV, alpha 1
chr8_-_82395461 9.38 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr3_+_138666070 9.35 ENST00000383165.3
chromosome 3 open reading frame 72
chr7_+_134576151 8.75 ENST00000393118.2
caldesmon 1
chr1_-_173793458 8.41 ENST00000356198.2
centromere protein L
chr2_+_242127924 8.15 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
anoctamin 7
chr16_+_30710462 7.92 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
Snf2-related CREBBP activator protein
chr1_-_173793246 7.88 ENST00000345664.6
ENST00000367710.3
centromere protein L
chr15_+_96875657 7.67 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr16_-_15950868 7.25 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
myosin, heavy chain 11, smooth muscle
chr2_-_208489707 6.71 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
methyltransferase like 21A
chr3_+_14989186 6.70 ENST00000435454.1
ENST00000323373.6
nuclear receptor subfamily 2, group C, member 2
chr19_+_39616410 6.68 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
p21 protein (Cdc42/Rac)-activated kinase 4
chr10_-_33625154 6.63 ENST00000265371.4
neuropilin 1
chr19_+_2977444 6.59 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr1_-_151965048 6.58 ENST00000368809.1
S100 calcium binding protein A10
chr15_+_64443905 6.34 ENST00000325881.4
sorting nexin 22
chr1_+_16083154 6.30 ENST00000375771.1
filamin binding LIM protein 1
chr7_-_107642348 6.24 ENST00000393561.1
laminin, beta 1
chr7_-_95225768 6.06 ENST00000005178.5
pyruvate dehydrogenase kinase, isozyme 4
chr11_-_104480019 5.94 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chr5_-_133747589 5.81 ENST00000458198.2
CDKN2A interacting protein N-terminal like
chr3_+_157154578 5.81 ENST00000295927.3
pentraxin 3, long
chr3_+_8543561 5.78 ENST00000397386.3
LIM and cysteine-rich domains 1
chr1_-_53387386 5.65 ENST00000467988.1
ENST00000358358.5
ENST00000371522.4
enoyl CoA hydratase domain containing 2
chr12_+_58013693 5.64 ENST00000320442.4
ENST00000379218.2
solute carrier family 26, member 10
chr3_+_37284824 5.51 ENST00000431105.1
golgin A4
chr4_+_124317940 5.39 ENST00000505319.1
ENST00000339241.1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr17_+_13972807 5.38 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
cytochrome c oxidase assembly homolog 10 (yeast)
chr20_+_54933971 5.35 ENST00000371384.3
ENST00000437418.1
family with sequence similarity 210, member B
chr11_+_308143 5.31 ENST00000399817.4
interferon induced transmembrane protein 2
chr7_-_27169801 5.28 ENST00000511914.1
homeobox A4
chr11_+_308217 5.18 ENST00000602569.1
interferon induced transmembrane protein 2
chr9_-_14313641 5.15 ENST00000380953.1
nuclear factor I/B
chr1_+_151739131 5.04 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr1_-_157108266 5.00 ENST00000326786.4
ets variant 3
chr3_+_8543393 4.79 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr22_+_29469100 4.76 ENST00000327813.5
ENST00000407188.1
kringle containing transmembrane protein 1
chr3_-_114790179 4.76 ENST00000462705.1
zinc finger and BTB domain containing 20
chr4_+_95972822 4.70 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr1_-_149858227 4.59 ENST00000369155.2
histone cluster 2, H2be
chr17_+_75137460 4.56 ENST00000587820.1
SEC14-like 1 (S. cerevisiae)
chr3_+_156544057 4.52 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr15_+_101420028 4.50 ENST00000557963.1
ENST00000346623.6
aldehyde dehydrogenase 1 family, member A3
chr16_-_28937027 4.49 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr14_+_75761099 4.45 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5
chr5_+_34656569 4.44 ENST00000428746.2
retinoic acid induced 14
chrX_+_135251835 4.43 ENST00000456445.1
four and a half LIM domains 1
chr8_-_9009079 4.31 ENST00000519699.1
protein phosphatase 1, regulatory subunit 3B
chr12_-_56106060 4.31 ENST00000452168.2
integrin, alpha 7
chr8_+_99956662 4.24 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
odd-skipped related transciption factor 2
chr20_+_43343886 4.24 ENST00000190983.4
WNT1 inducible signaling pathway protein 2
chr1_+_196788887 4.21 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr2_+_196313239 4.19 ENST00000413290.1
AC064834.1
chr22_-_38699003 4.19 ENST00000451964.1
casein kinase 1, epsilon
chr17_-_31204124 4.18 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
myosin ID
chr7_-_74221288 4.15 ENST00000451013.2
GTF2I repeat domain containing 2
chr15_-_81616446 4.15 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr19_-_38806560 4.15 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
Yip1 interacting factor homolog B (S. cerevisiae)
chr1_+_22962948 4.10 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr11_+_107461948 4.08 ENST00000265840.7
ENST00000443271.2
ELMO/CED-12 domain containing 1
chr3_+_8543533 4.07 ENST00000454244.1
LIM and cysteine-rich domains 1
chr11_+_66624527 4.04 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr2_+_223916862 4.00 ENST00000604125.1
potassium voltage-gated channel, Isk-related family, member 4
chr3_+_129247479 3.91 ENST00000296271.3
rhodopsin
chr7_+_100183927 3.87 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr8_+_37654424 3.84 ENST00000315215.7
G protein-coupled receptor 124
chr3_+_193853927 3.84 ENST00000232424.3
hes family bHLH transcription factor 1
chr14_+_23340822 3.79 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr6_+_7108210 3.79 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr22_+_29469012 3.78 ENST00000400335.4
ENST00000400338.2
kringle containing transmembrane protein 1
chr9_-_23825956 3.74 ENST00000397312.2
ELAV like neuron-specific RNA binding protein 2
chr5_-_131347501 3.67 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr16_+_28875126 3.66 ENST00000359285.5
ENST00000538342.1
SH2B adaptor protein 1
chr1_-_229569834 3.64 ENST00000366684.3
ENST00000366683.2
actin, alpha 1, skeletal muscle
chrX_+_102840408 3.63 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
transcription elongation factor A (SII)-like 4
chr9_+_37650945 3.57 ENST00000377765.3
FERM and PDZ domain containing 1
chr6_+_126102292 3.56 ENST00000368357.3
nuclear receptor coactivator 7
chr9_+_17135016 3.56 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr10_+_76586348 3.54 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr17_-_33905521 3.53 ENST00000225873.4
peroxisomal biogenesis factor 12
chr5_-_112630598 3.52 ENST00000302475.4
mutated in colorectal cancers
chr4_-_90229142 3.49 ENST00000609438.1
GPRIN family member 3
chr3_-_49722523 3.49 ENST00000448220.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chrX_+_103810874 3.48 ENST00000372582.1
interleukin 1 receptor accessory protein-like 2
chr9_-_14313893 3.46 ENST00000380921.3
ENST00000380959.3
nuclear factor I/B
chr2_+_171034646 3.40 ENST00000409044.3
ENST00000408978.4
myosin IIIB
chr6_+_149068464 3.30 ENST00000367463.4
uronyl-2-sulfotransferase
chr5_-_154230130 3.30 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
fatty acid hydroxylase domain containing 2
chr22_+_46546494 3.26 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
peroxisome proliferator-activated receptor alpha
chr9_+_17134980 3.26 ENST00000380647.3
centlein, centrosomal protein
chr14_+_22293618 3.25 ENST00000390432.2
T cell receptor alpha variable 10
chr2_+_219433281 3.25 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr8_+_11561660 3.21 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA binding protein 4
chr14_-_76447494 3.17 ENST00000238682.3
transforming growth factor, beta 3
chrX_+_49832231 3.15 ENST00000376108.3
chloride channel, voltage-sensitive 5
chr9_-_21368075 3.14 ENST00000449498.1
interferon, alpha 13
chr3_-_9994021 3.14 ENST00000411976.2
ENST00000412055.1
proline-rich transmembrane protein 3
chr9_-_115983641 3.13 ENST00000238256.3
FK506 binding protein 15, 133kDa
chr16_+_84209539 3.12 ENST00000569735.1
dynein, axonemal, assembly factor 1
chr1_+_46972668 3.12 ENST00000371956.4
ENST00000360032.3
diencephalon/mesencephalon homeobox 1
chrX_+_152990302 3.10 ENST00000218104.3
ATP-binding cassette, sub-family D (ALD), member 1
chr10_-_44070016 3.10 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
zinc finger protein 239
chr9_-_14314066 3.09 ENST00000397575.3
nuclear factor I/B
chr7_+_112090483 3.08 ENST00000403825.3
ENST00000429071.1
interferon-related developmental regulator 1
chr13_-_95364389 3.08 ENST00000376945.2
SRY (sex determining region Y)-box 21
chr8_+_99956759 3.05 ENST00000522510.1
ENST00000457907.2
odd-skipped related transciption factor 2
chr10_+_94833642 3.01 ENST00000224356.4
ENST00000394139.1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr11_-_108093329 3.01 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr13_+_25670268 2.98 ENST00000281589.3
poly(A) binding protein, cytoplasmic 3
chr6_+_7107830 2.87 ENST00000379933.3
ras responsive element binding protein 1
chr20_+_37590942 2.83 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr6_-_167040731 2.82 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr20_-_35724388 2.78 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr3_-_126373929 2.72 ENST00000523403.1
ENST00000524230.2
thioredoxin reductase 3
chr7_-_100183742 2.70 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr9_-_129884902 2.70 ENST00000373417.1
angiopoietin-like 2
chr2_+_18059906 2.68 ENST00000304101.4
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr1_-_120612240 2.67 ENST00000256646.2
notch 2
chr1_-_47407111 2.66 ENST00000371904.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chr2_+_183943464 2.66 ENST00000354221.4
dual specificity phosphatase 19
chrX_-_71525742 2.63 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr13_-_33112823 2.60 ENST00000504114.1
NEDD4 binding protein 2-like 2
chr6_+_31515337 2.58 ENST00000376148.4
ENST00000376145.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr1_+_15479021 2.57 ENST00000428417.1
transmembrane protein 51
chr11_-_108369101 2.52 ENST00000323468.5
KDEL (Lys-Asp-Glu-Leu) containing 2
chr17_-_2206801 2.51 ENST00000544865.1
SMG6 nonsense mediated mRNA decay factor
chr2_-_158732340 2.49 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
activin A receptor, type I
chr22_-_32341336 2.46 ENST00000248984.3
chromosome 22 open reading frame 24
chrX_-_30327495 2.38 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr12_-_114843889 2.38 ENST00000405440.2
T-box 5
chr1_+_173793641 2.35 ENST00000361951.4
aspartyl-tRNA synthetase 2, mitochondrial
chr7_-_100844193 2.29 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
monoacylglycerol O-acyltransferase 3
chr19_+_7011509 2.29 ENST00000377296.3
Uncharacterized protein
chr7_+_45613958 2.29 ENST00000297323.7
adenylate cyclase 1 (brain)
chr19_+_589893 2.26 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr11_+_108093559 2.26 ENST00000278616.4
ataxia telangiectasia mutated
chr5_-_112770674 2.23 ENST00000390666.3
testis-specific serine kinase 1B
chr11_-_66445219 2.19 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RNA binding motif protein 4B
chr7_+_87563557 2.17 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM metallopeptidase domain 22
chr13_-_33859819 2.15 ENST00000336934.5
StAR-related lipid transfer (START) domain containing 13
chr2_+_69240511 2.14 ENST00000409349.3
anthrax toxin receptor 1
chr3_+_37284668 2.14 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
golgin A4
chr17_+_33448593 2.13 ENST00000158009.5
fibronectin type III domain containing 8
chr1_-_20250110 2.12 ENST00000375116.3
phospholipase A2, group IIE
chr4_+_5712898 2.10 ENST00000264956.6
ENST00000382674.2
Ellis van Creveld syndrome
chrX_+_45364633 2.09 ENST00000435394.1
ENST00000609127.1
RP11-245M24.1
chr1_+_196912902 2.08 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr7_-_30518387 2.08 ENST00000222823.4
ENST00000419601.1
nucleotide-binding oligomerization domain containing 1
chr5_+_149546334 2.07 ENST00000231656.8
caudal type homeobox 1
chr2_+_69240302 2.07 ENST00000303714.4
anthrax toxin receptor 1
chr14_-_21492113 2.06 ENST00000554094.1
NDRG family member 2
chr12_+_54447637 2.06 ENST00000609810.1
ENST00000430889.2
homeobox C4
Homeobox protein Hox-C4
chr7_+_22766766 2.04 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chr16_+_83986827 2.03 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr22_-_24641027 2.03 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
gamma-glutamyltransferase 5
chrX_-_48216101 2.02 ENST00000298396.2
ENST00000376893.3
synovial sarcoma, X breakpoint 3
chr2_+_69240415 1.99 ENST00000409829.3
anthrax toxin receptor 1
chr6_+_27782788 1.98 ENST00000359465.4
histone cluster 1, H2bm
chr9_-_129885010 1.97 ENST00000373425.3
angiopoietin-like 2
chr4_-_168155169 1.97 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_28177255 1.97 ENST00000601459.1
HCG2032222; PRO2047; Uncharacterized protein
chr2_-_220083076 1.97 ENST00000295750.4
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr12_+_6494285 1.96 ENST00000541102.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr1_+_15479054 1.94 ENST00000376014.3
ENST00000451326.2
transmembrane protein 51
chr3_-_58196688 1.90 ENST00000486455.1
deoxyribonuclease I-like 3
chr19_+_40697514 1.87 ENST00000253055.3
mitogen-activated protein kinase kinase kinase 10
chr11_+_118478313 1.87 ENST00000356063.5
pleckstrin homology-like domain, family B, member 1
chr1_+_25943959 1.85 ENST00000374332.4
mannosidase, alpha, class 1C, member 1
chr8_+_67579807 1.85 ENST00000519289.1
ENST00000519561.1
ENST00000521889.1
C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr3_-_58196939 1.85 ENST00000394549.2
ENST00000461914.3
deoxyribonuclease I-like 3
chr1_+_55107449 1.84 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
maestro heat-like repeat family member 7
chr5_+_66124590 1.84 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
microtubule associated serine/threonine kinase family member 4
chr8_-_57359131 1.82 ENST00000518974.1
ENST00000523051.1
ENST00000518770.1
ENST00000451791.2
proenkephalin
chr5_+_140810132 1.80 ENST00000252085.3
protocadherin gamma subfamily A, 12
chr3_+_12330560 1.80 ENST00000397026.2
peroxisome proliferator-activated receptor gamma
chr5_+_137203465 1.79 ENST00000239926.4
myotilin
chr13_+_24844819 1.76 ENST00000399949.2
spermatogenesis associated 13
chr18_+_29027696 1.76 ENST00000257189.4
desmoglein 3
chr16_-_28936493 1.76 ENST00000544477.1
ENST00000357573.6
rabaptin, RAB GTPase binding effector protein 2
chr11_-_129872712 1.75 ENST00000358825.5
ENST00000360871.3
ENST00000528746.1
PR domain containing 10
chr5_+_125695805 1.73 ENST00000513040.1
GRAM domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 81.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
4.4 17.6 GO:0009956 radial pattern formation(GO:0009956)
3.7 11.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.5 2.5 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
2.4 7.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
2.3 9.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
2.1 4.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
2.1 6.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.9 9.6 GO:0035524 proline transmembrane transport(GO:0035524)
1.8 7.3 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
1.8 5.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.7 11.7 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.7 6.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
1.6 6.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.5 4.5 GO:0060166 olfactory pit development(GO:0060166)
1.3 6.6 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
1.2 22.5 GO:0007021 tubulin complex assembly(GO:0007021)
1.1 13.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
1.1 6.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.1 4.4 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
1.1 3.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
1.0 3.1 GO:0007518 myoblast fate determination(GO:0007518)
1.0 5.0 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.0 3.0 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.9 4.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.8 3.4 GO:0003095 pressure natriuresis(GO:0003095)
0.8 3.3 GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.8 5.6 GO:0019532 oxalate transport(GO:0019532)
0.8 4.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.8 3.2 GO:1905073 ossification involved in bone remodeling(GO:0043932) frontal suture morphogenesis(GO:0060364) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.8 2.4 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.8 3.9 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.8 2.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.8 3.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.8 2.3 GO:1904868 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.7 3.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.7 10.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.7 4.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.7 2.0 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.7 4.7 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.6 1.9 GO:0061113 pancreas morphogenesis(GO:0061113)
0.6 8.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.6 1.2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.6 14.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.6 9.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.5 16.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.5 2.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.5 1.6 GO:0038190 coronary vein morphogenesis(GO:0003169) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.5 3.0 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.5 1.5 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.5 6.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.5 1.4 GO:0060018 astrocyte fate commitment(GO:0060018)
0.5 5.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.5 25.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.5 1.8 GO:0051866 general adaptation syndrome(GO:0051866)
0.5 6.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.5 1.8 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.4 2.6 GO:0071105 response to interleukin-11(GO:0071105)
0.4 4.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 2.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.4 6.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 3.0 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.4 6.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 1.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.4 10.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.4 1.5 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.4 2.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.4 3.3 GO:0006477 protein sulfation(GO:0006477)
0.4 1.4 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3 2.1 GO:0016045 detection of bacterium(GO:0016045)
0.3 3.1 GO:0008343 adult feeding behavior(GO:0008343)
0.3 6.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.3 6.6 GO:0001765 membrane raft assembly(GO:0001765)
0.3 0.9 GO:0061056 sclerotome development(GO:0061056)
0.3 2.7 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.3 7.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 4.1 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.3 3.6 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.3 0.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 0.8 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3 5.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.3 1.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 0.8 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.3 12.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 3.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 3.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 1.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 4.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 3.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 1.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 0.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.9 GO:0035106 operant conditioning(GO:0035106)
0.2 3.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 2.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 1.1 GO:0051142 positive regulation of interferon-gamma biosynthetic process(GO:0045078) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2 1.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.2 4.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.2 2.3 GO:0010226 response to lithium ion(GO:0010226)
0.2 1.0 GO:0032571 response to vitamin K(GO:0032571)
0.2 3.7 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.2 0.8 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 2.0 GO:0015886 heme transport(GO:0015886)
0.2 3.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 2.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.9 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 2.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 1.0 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.6 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 2.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 2.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 2.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.5 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.9 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.4 GO:0070253 somatostatin secretion(GO:0070253) positive regulation of pancreatic juice secretion(GO:0090187)
0.1 1.6 GO:2000394 phosphatidylcholine catabolic process(GO:0034638) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 3.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 1.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 1.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.5 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.1 2.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 2.3 GO:0006853 carnitine shuttle(GO:0006853)
0.1 2.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 2.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 2.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 7.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 0.5 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
0.1 1.7 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 2.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 2.6 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.6 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 2.2 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 2.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.5 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 4.1 GO:0010039 response to iron ion(GO:0010039)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 4.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 7.8 GO:0060996 dendritic spine development(GO:0060996)
0.1 3.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 3.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.8 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 1.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 4.4 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.1 3.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.1 1.1 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 1.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.0 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 3.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 6.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 5.0 GO:0016573 histone acetylation(GO:0016573)
0.0 3.1 GO:0001942 hair follicle development(GO:0001942)
0.0 1.4 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 4.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.6 GO:0002251 organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385)
0.0 1.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.7 GO:0043588 skin development(GO:0043588)
0.0 23.4 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.8 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 1.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.0 GO:0001558 regulation of cell growth(GO:0001558)
0.0 3.4 GO:0048562 embryonic organ morphogenesis(GO:0048562)
0.0 5.1 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 2.4 GO:0048839 inner ear development(GO:0048839)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.5 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 1.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 2.2 GO:0007286 spermatid development(GO:0007286)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 2.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.3 GO:0030728 ovulation(GO:0030728)
0.0 2.6 GO:0006664 glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)
0.0 0.4 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 2.6 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.6 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 1.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 81.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.1 6.2 GO:0005607 laminin-2 complex(GO:0005607)
1.5 24.1 GO:0097512 cardiac myofibril(GO:0097512)
1.2 9.4 GO:0005587 collagen type IV trimer(GO:0005587)
1.1 12.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.0 11.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.8 4.1 GO:0005602 complement component C1 complex(GO:0005602)
0.7 3.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.7 9.6 GO:0005577 fibrinogen complex(GO:0005577)
0.6 6.6 GO:0002116 semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443)
0.6 8.7 GO:0030478 actin cap(GO:0030478)
0.5 2.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 4.3 GO:0042587 glycogen granule(GO:0042587)
0.4 3.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.4 4.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 3.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 1.8 GO:0032280 symmetric synapse(GO:0032280)
0.3 7.2 GO:0032982 myosin filament(GO:0032982)
0.3 6.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 3.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 6.3 GO:0012506 vesicle membrane(GO:0012506) cytoplasmic vesicle membrane(GO:0030659)
0.2 2.4 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 6.3 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.2 10.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 4.2 GO:0097440 apical dendrite(GO:0097440)
0.2 2.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 7.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 6.2 GO:0031527 filopodium membrane(GO:0031527)
0.2 1.9 GO:0045180 basal cortex(GO:0045180)
0.2 2.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 7.0 GO:0000786 nucleosome(GO:0000786)
0.1 2.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 17.7 GO:0001650 fibrillar center(GO:0001650)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.5 GO:0090543 Flemming body(GO:0090543)
0.1 1.1 GO:0043235 receptor complex(GO:0043235)
0.1 9.0 GO:0005811 lipid particle(GO:0005811)
0.1 3.7 GO:0044439 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 4.3 GO:0008305 integrin complex(GO:0008305)
0.1 1.7 GO:0005922 connexon complex(GO:0005922)
0.1 1.1 GO:0031906 late endosome lumen(GO:0031906)
0.1 1.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 3.7 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 6.5 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.8 GO:0030057 desmosome(GO:0030057)
0.1 7.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 8.9 GO:0072562 blood microparticle(GO:0072562)
0.1 0.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 6.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 5.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 3.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 9.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 3.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 7.8 GO:0030426 growth cone(GO:0030426)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 2.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 7.1 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 2.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 6.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 21.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.6 GO:0005814 centriole(GO:0005814)
0.0 5.3 GO:0030027 lamellipodium(GO:0030027)
0.0 1.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 5.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 5.6 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.5 GO:0016605 PML body(GO:0016605)
0.0 4.4 GO:0005925 focal adhesion(GO:0005925)
0.0 1.4 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 5.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
3.2 9.6 GO:0070052 collagen V binding(GO:0070052)
2.1 10.7 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
1.9 9.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.5 6.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.4 4.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.3 10.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
1.2 82.8 GO:0050840 extracellular matrix binding(GO:0050840)
1.1 3.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
1.0 5.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.9 5.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.9 5.1 GO:0039552 RIG-I binding(GO:0039552)
0.8 3.4 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.8 1.7 GO:0030172 troponin C binding(GO:0030172)
0.8 7.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.8 2.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.7 8.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.7 6.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.7 3.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.7 20.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.7 2.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.6 7.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.6 6.5 GO:0051525 NFAT protein binding(GO:0051525)
0.6 2.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.5 2.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 1.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.5 4.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 5.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.5 2.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.5 1.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 18.4 GO:0001972 retinoic acid binding(GO:0001972)
0.4 2.7 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.4 3.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 6.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.4 2.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.4 4.4 GO:0050693 LBD domain binding(GO:0050693)
0.4 1.5 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.4 0.7 GO:0005319 lipid transporter activity(GO:0005319)
0.4 3.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 1.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.3 3.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 6.3 GO:0031005 filamin binding(GO:0031005)
0.3 7.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 8.7 GO:0005523 tropomyosin binding(GO:0005523)
0.3 1.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 1.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 2.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 2.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 2.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 1.8 GO:0001515 opioid peptide activity(GO:0001515)
0.3 4.1 GO:0032052 bile acid binding(GO:0032052)
0.3 2.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 3.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 5.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.6 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 1.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 3.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 0.8 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 0.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 3.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 9.0 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.9 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 2.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 4.8 GO:0070840 dynein complex binding(GO:0070840)
0.2 16.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 2.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.2 3.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.2 34.7 GO:0051015 actin filament binding(GO:0051015)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 3.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 4.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 6.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 10.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 2.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 2.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 4.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 8.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 17.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 19.2 GO:0044325 ion channel binding(GO:0044325)
0.1 1.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 4.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 2.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 2.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.6 GO:0043531 ADP binding(GO:0043531)
0.1 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 16.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 6.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.5 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 3.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 28.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 2.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 1.1 GO:0019864 IgG binding(GO:0019864)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 10.8 GO:0008083 growth factor activity(GO:0008083)
0.1 3.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 3.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 2.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 3.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 4.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.9 GO:0005506 iron ion binding(GO:0005506)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 8.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.5 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 2.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 81.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 8.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 25.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 22.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 8.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 8.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 9.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 4.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 11.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 1.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 1.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 5.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 15.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 22.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 5.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 4.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 3.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.7 PID BMP PATHWAY BMP receptor signaling
0.1 2.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 15.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 5.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 81.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 5.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 9.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 8.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 4.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 11.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.4 6.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 3.9 REACTOME OPSINS Genes involved in Opsins
0.3 32.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 16.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 2.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 2.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 5.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 3.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 4.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 25.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 3.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 3.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 7.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 16.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 7.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 4.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 4.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 4.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 3.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 1.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 5.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 5.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 4.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 5.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones