Project

averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR1I2

Z-value: 1.29

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Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
ENSG00000144852.12 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119499331_119499331,
hg19_v2_chr3_+_119501557_119501557
0.306.1e-06Click!

Activity profile of NR1I2 motif

721_B_lymphoblasts AmygdalaBM-CD33+MyeloidbronchialepithelialcellsCerebellumPedunclesDRGfetalThyroidkidneyLiverlymphomaburkittsRajiOvaryPB-BDCA4+Dentritic_CellsPB-CD56+NKCellsPonsSkeletalMusclesubthalamicnucleusTestisGermCellThalamusTonsilUterusCorpusNCI60_1_A498NCI60_1_CAKI-1NCI60_1_EKVXNCI60_1_HL-60NCI60_1_HT29NCI60_1_KM12NCI60_1_MCF7NCI60_1_MOLT-4NCI60_1_NCI-H460NCI60_1_OVCAR-5NCI60_1_RXF-393NCI60_1_SK-MEL-28NCI60_1_SN12CNCI60_1_SW-620NCI60_1_UACC-257−0.15−0.1−0.0500.050.10.15
activity (log2(tpm) per TFBS)

Sorted Z-values of NR1I2 motif

−3−2−1012345721_B_lymphoblasts CingulateCortexNCI60_1_IGROV1_rep2fetalbrainNCI60_1_K-562PB-CD19+BcellsNCI60_1_CCRF-CEMNCI60_1_SRNCI60_1_MOLT-4ParietalLobeBM-CD33+MyeloidNCI60_1_MCF7NCI60_1_SK-OV-3Pancreasleukemiapromyelocytic(hl60)NCI60_1_U251PB-CD4+TcellsNCI60_1_TK-10NCI60_1_SNB-19cerebellumNCI60_1_SK-MEL-5CerebellumPedunclesspinalcordThyroidNCI60_1_M14bronchialepithelialcellsTestisInterstitialNCI60_1_HS578TNCI60_1_SNB-75SkeletalMuscleCardiacMyocytesSuperiorCervicalGanglionatrioventricularnodeAppendixUterus
Z-value

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: