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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR2F2

Z-value: 1.07

Motif logo

Transcription factors associated with NR2F2

Gene Symbol Gene ID Gene Info
ENSG00000185551.8 nuclear receptor subfamily 2 group F member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2F2hg19_v2_chr15_+_96875657_968757940.381.0e-08Click!

Activity profile of NR2F2 motif

Sorted Z-values of NR2F2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_23607598 13.02 ENST00000562133.1
ENST00000570319.1
ENST00000007516.3
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr15_-_63448973 10.81 ENST00000462430.1
ribosomal protein S27-like
chr7_+_116139744 10.50 ENST00000343213.2
caveolin 2
chrX_+_118602363 10.21 ENST00000317881.8
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr3_-_185641681 10.05 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr14_-_24616426 9.88 ENST00000216802.5
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr2_+_201170770 9.67 ENST00000409988.3
ENST00000409385.1
spermatogenesis associated, serine-rich 2-like
chr12_+_52626898 9.49 ENST00000331817.5
keratin 7
chr19_+_36631867 9.36 ENST00000588780.1
calpain, small subunit 1
chr8_-_121457332 9.07 ENST00000518918.1
mitochondrial ribosomal protein L13
chr19_+_572543 9.02 ENST00000333511.3
ENST00000573216.1
ENST00000353555.4
basigin (Ok blood group)
chr15_+_22892663 8.46 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
cytoplasmic FMR1 interacting protein 1
chr18_+_12948000 8.38 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr2_-_151344172 8.12 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chrX_+_13707235 7.99 ENST00000464506.1
RAB9A, member RAS oncogene family
chr10_+_115438920 7.69 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr13_+_28195988 7.57 ENST00000399697.3
ENST00000399696.1
polymerase (RNA) I polypeptide D, 16kDa
chr8_-_101965559 7.51 ENST00000353245.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr14_+_24605389 7.41 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr14_+_23791159 7.28 ENST00000557702.1
poly(A) binding protein, nuclear 1
chr4_+_107236692 7.27 ENST00000510207.1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr4_-_140223614 7.27 ENST00000394223.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_-_42463418 7.18 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
Rab acceptor 1 (prenylated)
chr5_+_33440802 7.11 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
threonyl-tRNA synthetase
chr8_-_71520513 7.10 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
translocation associated membrane protein 1
chr14_+_23790690 7.03 ENST00000556821.1
poly(A) binding protein, nuclear 1
chr5_+_1801503 6.98 ENST00000274137.5
ENST00000469176.1
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr4_-_183838596 6.95 ENST00000508994.1
ENST00000512766.1
dCMP deaminase
chr20_+_44520009 6.89 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr1_+_165796753 6.75 ENST00000367879.4
uridine-cytidine kinase 2
chr20_+_44519948 6.69 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr5_-_131563501 6.67 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
prolyl 4-hydroxylase, alpha polypeptide II
chr8_-_121457608 6.61 ENST00000306185.3
mitochondrial ribosomal protein L13
chr13_+_43597269 6.61 ENST00000379221.2
DnaJ (Hsp40) homolog, subfamily C, member 15
chr13_+_113951607 6.50 ENST00000397181.3
lysosomal-associated membrane protein 1
chr4_-_140223670 6.49 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr22_-_19165917 6.41 ENST00000451283.1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_-_73178599 6.36 ENST00000578238.1
small ubiquitin-like modifier 2
chr2_+_15731289 6.33 ENST00000381341.2
DEAD (Asp-Glu-Ala-Asp) box helicase 1
chr2_+_189157536 6.23 ENST00000409580.1
ENST00000409637.3
GULP, engulfment adaptor PTB domain containing 1
chr2_+_189157498 6.12 ENST00000359135.3
GULP, engulfment adaptor PTB domain containing 1
chr1_+_44440575 6.11 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr5_-_131562935 6.07 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
prolyl 4-hydroxylase, alpha polypeptide II
chr1_+_32687971 6.00 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr15_-_66790146 6.00 ENST00000316634.5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr12_+_16035307 5.97 ENST00000538352.1
ENST00000025399.6
ENST00000419869.2
serine/threonine kinase receptor associated protein
chr19_-_55919087 5.96 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr21_-_43187231 5.93 ENST00000332512.3
ENST00000352483.2
receptor-interacting serine-threonine kinase 4
chr19_+_36630961 5.89 ENST00000587718.1
ENST00000592483.1
ENST00000590874.1
ENST00000588815.1
calpain, small subunit 1
chr11_+_1968508 5.88 ENST00000397298.3
ENST00000381519.1
ENST00000397297.3
ENST00000381514.3
ENST00000397294.3
mitochondrial ribosomal protein L23
chr11_-_65325430 5.84 ENST00000322147.4
latent transforming growth factor beta binding protein 3
chr1_-_3816779 5.78 ENST00000361605.3
chromosome 1 open reading frame 174
chr13_+_76123883 5.77 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr11_-_65308082 5.72 ENST00000532661.1
latent transforming growth factor beta binding protein 3
chr7_-_105752971 5.69 ENST00000011473.2
synaptophysin-like 1
chr17_-_47785504 5.66 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
solute carrier family 35, member B1
chr11_-_8986474 5.58 ENST00000525069.1
TMEM9 domain family, member B
chr20_-_5107180 5.56 ENST00000379160.3
proliferating cell nuclear antigen
chr17_-_4843206 5.54 ENST00000576951.1
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr2_+_192110199 5.53 ENST00000304164.4
myosin IB
chr5_+_68530668 5.49 ENST00000506563.1
cyclin-dependent kinase 7
chr22_+_50312379 5.47 ENST00000407217.3
ENST00000403427.3
cysteine-rich with EGF-like domains 2
chr15_-_37393406 5.46 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr3_-_107941230 5.46 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr6_-_2971792 5.37 ENST00000380546.3
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr4_-_183838747 5.29 ENST00000438320.2
dCMP deaminase
chr19_+_54694119 5.27 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34 tRNA splicing endonuclease subunit
chr2_-_150444116 5.27 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr1_+_223889285 5.27 ENST00000433674.2
calpain 2, (m/II) large subunit
chr19_+_16186903 5.26 ENST00000588507.1
tropomyosin 4
chr2_-_62115659 5.25 ENST00000544185.1
chaperonin containing TCP1, subunit 4 (delta)
chr1_-_150208498 5.22 ENST00000314136.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_-_150444300 5.22 ENST00000303319.5
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr14_-_100841670 5.22 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
tryptophanyl-tRNA synthetase
chr7_+_5085452 5.21 ENST00000353796.3
ENST00000396912.1
ENST00000396904.2
RB-associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr7_-_45960850 5.18 ENST00000381083.4
ENST00000381086.5
ENST00000275521.6
insulin-like growth factor binding protein 3
chr4_+_39699664 5.17 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
ubiquitin-conjugating enzyme E2K
chr6_-_2971429 5.14 ENST00000380529.1
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr5_+_177019159 5.12 ENST00000332598.6
transmembrane emp24 protein transport domain containing 9
chr14_+_103801140 5.09 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
eukaryotic translation initiation factor 5
chr10_+_70748487 5.09 ENST00000361983.4
KIAA1279
chr2_-_3523507 5.02 ENST00000327435.6
acireductone dioxygenase 1
chr14_+_52456327 4.99 ENST00000556760.1
chromosome 14 open reading frame 166
chr2_-_62115725 4.98 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
chaperonin containing TCP1, subunit 4 (delta)
chr15_-_90777277 4.96 ENST00000328649.6
calcium and integrin binding 1 (calmyrin)
chr14_+_52456193 4.95 ENST00000261700.3
chromosome 14 open reading frame 166
chr14_-_74959978 4.92 ENST00000541064.1
Niemann-Pick disease, type C2
chr18_+_19749386 4.92 ENST00000269216.3
GATA binding protein 6
chr17_+_66244071 4.90 ENST00000580548.1
ENST00000580753.1
ENST00000392720.2
ENST00000359783.4
ENST00000584837.1
ENST00000579724.1
ENST00000584494.1
ENST00000580837.1
archaelysin family metallopeptidase 2
chr14_+_93651296 4.87 ENST00000283534.4
ENST00000557574.1
transmembrane protein 251
Uncharacterized protein
chr2_-_264024 4.87 ENST00000403712.2
ENST00000356150.5
ENST00000405430.1
SH3 and SYLF domain containing 1
chr14_+_24605361 4.84 ENST00000206451.6
ENST00000559123.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr6_-_2971494 4.81 ENST00000380539.1
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr14_-_74960030 4.79 ENST00000553490.1
ENST00000557510.1
Niemann-Pick disease, type C2
chr6_-_5260963 4.77 ENST00000464010.1
ENST00000468929.1
ENST00000480566.1
LYR motif containing 4
chr22_+_24309089 4.77 ENST00000215770.5
D-dopachrome tautomerase-like
chr3_+_52232102 4.74 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
aminolevulinate, delta-, synthase 1
chr19_-_13068012 4.73 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr10_+_51565108 4.71 ENST00000438493.1
ENST00000452682.1
nuclear receptor coactivator 4
chr18_+_12947981 4.71 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr2_+_63816295 4.71 ENST00000539945.1
ENST00000544381.1
malate dehydrogenase 1, NAD (soluble)
chr14_-_45603657 4.71 ENST00000396062.3
FK506 binding protein 3, 25kDa
chr5_+_33441053 4.66 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
threonyl-tRNA synthetase
chr9_+_127631399 4.65 ENST00000259477.6
actin related protein 2/3 complex, subunit 5-like
chr3_-_183602515 4.64 ENST00000449306.1
ENST00000435888.1
ENST00000311101.5
ENST00000317096.4
presenilin associated, rhomboid-like
chr1_+_155178481 4.63 ENST00000368376.3
metaxin 1
chr7_+_79764104 4.61 ENST00000351004.3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr7_-_107642348 4.57 ENST00000393561.1
laminin, beta 1
chr16_-_11680791 4.54 ENST00000571976.1
ENST00000413364.2
lipopolysaccharide-induced TNF factor
chr17_+_42427826 4.52 ENST00000586443.1
granulin
chr17_+_15902694 4.52 ENST00000261647.5
ENST00000486880.2
tetratricopeptide repeat domain 19
chr1_-_43855444 4.50 ENST00000372455.4
mediator complex subunit 8
chr14_-_74959994 4.50 ENST00000238633.2
ENST00000434013.2
Niemann-Pick disease, type C2
chr22_-_32058166 4.41 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr10_+_89419370 4.37 ENST00000361175.4
ENST00000456849.1
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr7_+_2394445 4.36 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
eukaryotic translation initiation factor 3, subunit B
chr10_+_51565188 4.32 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
nuclear receptor coactivator 4
chr7_+_143079000 4.32 ENST00000392910.2
zyxin
chr8_+_37887772 4.30 ENST00000338825.4
eukaryotic translation initiation factor 4E binding protein 1
chr2_-_37899323 4.30 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr9_-_116172617 4.26 ENST00000374169.3
polymerase (DNA directed), epsilon 3, accessory subunit
chrX_+_54834004 4.25 ENST00000375068.1
melanoma antigen family D, 2
chr2_-_86790593 4.25 ENST00000263856.4
ENST00000409225.2
charged multivesicular body protein 3
chr22_+_21996549 4.24 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr21_+_47518011 4.24 ENST00000300527.4
ENST00000357838.4
ENST00000310645.5
collagen, type VI, alpha 2
chr5_+_68530697 4.16 ENST00000256443.3
ENST00000514676.1
cyclin-dependent kinase 7
chr14_+_93651358 4.12 ENST00000415050.2
transmembrane protein 251
chr14_-_105262055 4.10 ENST00000349310.3
v-akt murine thymoma viral oncogene homolog 1
chr21_-_27107344 4.09 ENST00000457143.2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr9_-_116172946 4.07 ENST00000374171.4
polymerase (DNA directed), epsilon 3, accessory subunit
chr3_+_184079492 4.07 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
polymerase (RNA) II (DNA directed) polypeptide H
chr12_+_4758264 4.04 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr13_+_113951532 4.03 ENST00000332556.4
lysosomal-associated membrane protein 1
chr1_+_43996518 4.03 ENST00000359947.4
ENST00000438120.1
protein tyrosine phosphatase, receptor type, F
chr16_+_14726672 4.03 ENST00000261658.2
ENST00000563971.1
bifunctional apoptosis regulator
chr2_+_264869 4.03 ENST00000272067.6
ENST00000272065.5
ENST00000407983.3
acid phosphatase 1, soluble
chr15_-_75248954 4.01 ENST00000499788.2
ribonuclease P/MRP 25kDa subunit
chr12_+_102091400 4.00 ENST00000229266.3
ENST00000549872.1
choline phosphotransferase 1
chr1_-_110950255 4.00 ENST00000483260.1
ENST00000474861.2
ENST00000602318.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr16_-_69364467 4.00 ENST00000288022.1
peptide deformylase (mitochondrial)
chr21_-_27107198 3.98 ENST00000400094.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr8_+_48920960 3.97 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr5_-_114961858 3.96 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr8_+_97274119 3.93 ENST00000455950.2
phosphatidylserine synthase 1
chr1_-_150207017 3.91 ENST00000369119.3
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_53704157 3.91 ENST00000371466.4
ENST00000371470.3
mago-nashi homolog, proliferation-associated (Drosophila)
chr1_-_19638566 3.90 ENST00000330072.5
ENST00000235835.3
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
chr14_-_105262016 3.90 ENST00000407796.2
v-akt murine thymoma viral oncogene homolog 1
chr17_-_80231300 3.87 ENST00000398519.5
ENST00000580446.1
casein kinase 1, delta
chrX_+_54834791 3.86 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
melanoma antigen family D, 2
chr15_+_75628394 3.85 ENST00000564815.1
ENST00000338995.6
COMM domain containing 4
chr3_-_142608001 3.83 ENST00000295992.3
procollagen C-endopeptidase enhancer 2
chr20_+_34129770 3.81 ENST00000348547.2
ENST00000357394.4
ENST00000447986.1
ENST00000279052.6
ENST00000416206.1
ENST00000411577.1
ENST00000413587.1
ERGIC and golgi 3
chr17_+_79650962 3.79 ENST00000329138.4
hepatocyte growth factor-regulated tyrosine kinase substrate
chr15_+_75628232 3.79 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4
chr20_+_25388293 3.79 ENST00000262460.4
ENST00000429262.2
GINS complex subunit 1 (Psf1 homolog)
chr19_-_2050852 3.78 ENST00000541165.1
ENST00000591601.1
MAP kinase interacting serine/threonine kinase 2
chr17_-_73179046 3.77 ENST00000314523.7
ENST00000420826.2
small ubiquitin-like modifier 2
chr12_+_7033616 3.76 ENST00000356654.4
atrophin 1
chr6_-_127664736 3.76 ENST00000368291.2
ENST00000309620.9
ENST00000454859.3
enoyl CoA hydratase domain containing 1
chr4_+_39699776 3.75 ENST00000503368.1
ENST00000445950.2
ubiquitin-conjugating enzyme E2K
chr9_-_127952187 3.73 ENST00000451402.1
ENST00000415905.1
protein phosphatase 6, catalytic subunit
chr1_-_68962805 3.73 ENST00000370966.5
DEP domain containing 1
chr19_-_4540486 3.72 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr4_+_110354928 3.72 ENST00000504968.2
ENST00000399100.2
ENST00000265175.5
SEC24 family member B
chr17_+_8191815 3.70 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr6_-_127664683 3.69 ENST00000528402.1
ENST00000454591.2
enoyl CoA hydratase domain containing 1
chr1_-_211848899 3.68 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NIMA-related kinase 2
chr6_+_29910301 3.67 ENST00000376809.5
ENST00000376802.2
major histocompatibility complex, class I, A
chr4_+_107236722 3.67 ENST00000442366.1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chrX_+_38660704 3.64 ENST00000378474.3
MID1 interacting protein 1
chr16_-_29875057 3.64 ENST00000219789.6
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr7_+_148395733 3.63 ENST00000602748.1
cullin 1
chr22_+_38349670 3.62 ENST00000442738.2
ENST00000460648.1
ENST00000407936.1
ENST00000488684.1
ENST00000492213.1
ENST00000606538.1
ENST00000405557.1
polymerase (RNA) II (DNA directed) polypeptide F
chr21_-_27107283 3.62 ENST00000284971.3
ENST00000400099.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr4_+_107236847 3.54 ENST00000358008.3
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chrX_+_38660682 3.51 ENST00000457894.1
MID1 interacting protein 1
chr16_+_69458428 3.47 ENST00000512062.1
ENST00000307892.8
cytochrome b5 type B (outer mitochondrial membrane)
chr1_+_76190357 3.43 ENST00000370834.5
ENST00000541113.1
ENST00000543667.1
ENST00000420607.2
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr3_+_49059038 3.42 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr16_-_11680759 3.42 ENST00000571459.1
ENST00000570798.1
ENST00000572255.1
ENST00000574763.1
ENST00000574703.1
ENST00000571277.1
ENST00000381810.3
lipopolysaccharide-induced TNF factor
chr17_+_57784826 3.42 ENST00000262291.4
vacuole membrane protein 1
chr7_+_150065879 3.42 ENST00000397281.2
ENST00000444957.1
ENST00000466559.1
ENST00000489432.2
ENST00000475514.1
ENST00000482680.1
ENST00000488943.1
ENST00000518514.1
ENST00000478789.1
replication initiator 1
zinc finger protein 775
chr17_-_53809473 3.40 ENST00000575734.1
transmembrane protein 100
chr6_+_7541845 3.37 ENST00000418664.2
desmoplakin
chr6_-_35888905 3.37 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr3_+_127317066 3.36 ENST00000265056.7
minichromosome maintenance complex component 2
chr20_+_388935 3.31 ENST00000382181.2
ENST00000400247.3
RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_155178518 3.31 ENST00000316721.4
metaxin 1
chr17_-_72864739 3.31 ENST00000579893.1
ENST00000544854.1
ferredoxin reductase
chrX_+_11129388 3.29 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr22_+_45072958 3.29 ENST00000403581.1
proline rich 5 (renal)
chr22_+_45072925 3.28 ENST00000006251.7
proline rich 5 (renal)
chr22_+_37415776 3.27 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
mercaptopyruvate sulfurtransferase
chr3_-_52486841 3.27 ENST00000496590.1
troponin C type 1 (slow)
chr5_+_138609441 3.22 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr9_-_79009414 3.21 ENST00000376736.1
riboflavin kinase
chr14_-_75536182 3.20 ENST00000555463.1
acylphosphatase 1, erythrocyte (common) type
chr12_-_125348329 3.19 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
scavenger receptor class B, member 1
chr20_+_43160409 3.19 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 6.6 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
5.8 17.4 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
3.9 11.8 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
3.6 14.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
2.9 11.6 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
2.6 10.5 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
2.5 10.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
2.2 6.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
2.1 8.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
2.0 18.3 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
2.0 6.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
1.9 13.6 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
1.9 5.7 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
1.9 5.6 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
1.8 21.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.7 10.5 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
1.7 10.2 GO:1901029 adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
1.7 11.9 GO:0070294 renal sodium ion absorption(GO:0070294)
1.7 6.7 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
1.7 6.6 GO:0002086 diaphragm contraction(GO:0002086)
1.7 5.0 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
1.6 4.9 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
1.6 6.4 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.5 13.6 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
1.3 13.0 GO:0009249 protein lipoylation(GO:0009249)
1.3 7.8 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
1.3 5.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.3 8.9 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
1.2 8.3 GO:0038203 TORC2 signaling(GO:0038203)
1.2 4.7 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
1.2 7.0 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
1.1 3.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.1 4.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.1 8.0 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
1.1 5.5 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
1.1 4.4 GO:0000103 sulfate assimilation(GO:0000103)
1.1 13.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
1.1 3.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
1.0 5.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
1.0 3.1 GO:1901355 response to rapamycin(GO:1901355)
1.0 10.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
1.0 4.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
1.0 7.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.9 3.7 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.9 2.8 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.9 2.7 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.9 4.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.9 2.6 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.8 12.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.8 3.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.8 3.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.8 5.7 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.8 2.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.7 3.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.7 2.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.7 17.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.7 10.4 GO:0090168 Golgi reassembly(GO:0090168)
0.7 6.9 GO:0010265 SCF complex assembly(GO:0010265)
0.7 2.0 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.7 4.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7 2.6 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.6 1.9 GO:0007518 myoblast fate determination(GO:0007518)
0.6 1.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.6 7.2 GO:0006108 malate metabolic process(GO:0006108)
0.6 2.4 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.6 18.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.6 27.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.6 4.0 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.6 2.3 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.6 6.9 GO:0046689 response to mercury ion(GO:0046689)
0.6 2.8 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.6 4.5 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.6 5.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.6 2.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 7.7 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.5 2.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.5 4.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.5 3.2 GO:0014805 smooth muscle adaptation(GO:0014805)
0.5 1.6 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.5 4.3 GO:1902188 positive regulation of viral release from host cell(GO:1902188)
0.5 2.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5 3.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.5 3.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.5 1.4 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.5 19.1 GO:0042407 cristae formation(GO:0042407)
0.5 1.4 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.5 18.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.5 2.8 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 3.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.5 4.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.5 3.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.5 1.4 GO:0050894 determination of affect(GO:0050894)
0.4 1.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.4 0.9 GO:0051683 establishment of Golgi localization(GO:0051683)
0.4 11.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.4 30.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 1.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.4 2.9 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.4 2.0 GO:0061107 prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.4 3.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 7.3 GO:0006853 carnitine shuttle(GO:0006853)
0.4 3.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 4.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.4 14.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.4 3.9 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.4 2.7 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.4 1.5 GO:0003409 optic cup structural organization(GO:0003409)
0.4 5.7 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.4 3.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 1.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 3.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 4.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.4 3.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.4 2.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.4 2.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 3.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 1.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 2.7 GO:0001955 blood vessel maturation(GO:0001955)
0.3 5.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3 3.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 5.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.3 4.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.3 4.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 0.7 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.3 4.2 GO:0002192 IRES-dependent translational initiation(GO:0002192)
0.3 1.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.3 1.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.3 5.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.3 7.9 GO:0007035 vacuolar acidification(GO:0007035)
0.3 0.3 GO:0035973 aggrephagy(GO:0035973)
0.3 22.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 5.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 1.8 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.3 2.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.3 1.5 GO:0051013 microtubule severing(GO:0051013)
0.3 8.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.3 3.8 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.3 17.1 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 6.2 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.2 2.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 1.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 10.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.2 4.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 3.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 3.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.5 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 3.3 GO:0017004 cytochrome complex assembly(GO:0017004)
0.2 4.1 GO:0016540 protein autoprocessing(GO:0016540)
0.2 1.3 GO:1903147 negative regulation of macromitophagy(GO:1901525) negative regulation of mitophagy(GO:1903147)
0.2 1.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 5.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 9.2 GO:0043486 histone exchange(GO:0043486)
0.2 0.8 GO:0002572 pro-T cell differentiation(GO:0002572)
0.2 1.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 3.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 3.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.6 GO:0015879 carnitine transport(GO:0015879)
0.2 1.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 3.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.5 GO:0006612 protein targeting to membrane(GO:0006612)
0.2 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 3.0 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.2 2.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 6.9 GO:0097178 ruffle assembly(GO:0097178)
0.2 1.6 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.2 1.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 0.5 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.2 17.8 GO:0070268 cornification(GO:0070268)
0.1 2.2 GO:0090383 phagosome acidification(GO:0090383)
0.1 2.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.5 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 4.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.5 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 1.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 2.6 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 2.9 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 2.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 1.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 3.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 2.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 4.7 GO:0018208 peptidyl-proline modification(GO:0018208)
0.1 0.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.2 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 13.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 3.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 2.9 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.1 1.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 3.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 1.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 5.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 3.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 4.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 2.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 9.0 GO:0006413 translational initiation(GO:0006413)
0.1 0.4 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.0 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 1.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 0.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 3.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.4 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 3.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.7 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 5.5 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 1.6 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 7.5 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.4 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 1.0 GO:0042921 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 2.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269) ER-associated misfolded protein catabolic process(GO:0071712)
0.0 2.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.5 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 2.4 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 2.6 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.6 GO:0006260 DNA replication(GO:0006260)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 1.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 3.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 5.7 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.5 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 1.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 2.0 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 1.5 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 2.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 22.1 GO:0008537 proteasome activator complex(GO:0008537)
2.9 14.5 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
2.4 9.7 GO:0070985 TFIIK complex(GO:0070985)
2.3 16.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.9 13.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
1.9 5.6 GO:0070557 PCNA-p21 complex(GO:0070557)
1.7 25.7 GO:0044754 autolysosome(GO:0044754)
1.7 10.2 GO:0071817 MMXD complex(GO:0071817)
1.7 8.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.5 4.6 GO:0005607 laminin-2 complex(GO:0005607)
1.5 10.2 GO:0061700 GATOR2 complex(GO:0061700)
1.3 8.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
1.3 4.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
1.3 5.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.3 3.8 GO:0033565 ESCRT-0 complex(GO:0033565)
1.2 13.9 GO:0044292 dendrite terminus(GO:0044292)
1.2 17.4 GO:0042405 nuclear inclusion body(GO:0042405)
1.2 10.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.0 17.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.9 3.8 GO:0000811 GINS complex(GO:0000811)
0.9 5.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.8 4.0 GO:0071986 Ragulator complex(GO:0071986)
0.8 21.4 GO:0002080 acrosomal membrane(GO:0002080)
0.8 10.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.8 5.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.8 2.3 GO:0071159 NF-kappaB complex(GO:0071159)
0.7 2.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.7 13.9 GO:0032433 filopodium tip(GO:0032433)
0.7 2.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.7 9.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7 3.4 GO:0071797 LUBAC complex(GO:0071797)
0.7 6.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7 6.0 GO:0032797 SMN complex(GO:0032797)
0.6 11.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6 3.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.6 11.4 GO:0038201 TOR complex(GO:0038201)
0.6 5.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.6 5.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.6 37.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.6 22.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.5 3.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.5 3.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 3.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 3.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.4 2.6 GO:0001740 Barr body(GO:0001740)
0.4 4.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.4 1.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 2.4 GO:1902560 GMP reductase complex(GO:1902560)
0.4 1.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.4 27.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 4.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 2.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 5.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 3.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 4.2 GO:0000815 ESCRT III complex(GO:0000815)
0.3 1.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 2.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3 1.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.3 0.9 GO:0043291 RAVE complex(GO:0043291)
0.3 8.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 1.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 1.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.3 5.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 4.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 3.0 GO:0005642 annulate lamellae(GO:0005642)
0.3 1.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 5.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 4.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 4.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 3.9 GO:0097225 sperm midpiece(GO:0097225)
0.2 22.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 4.7 GO:0000812 Swr1 complex(GO:0000812)
0.2 4.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 3.1 GO:0008091 spectrin(GO:0008091)
0.2 0.7 GO:0030689 Noc complex(GO:0030689)
0.2 16.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 3.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.8 GO:0070695 FHF complex(GO:0070695)
0.2 8.7 GO:0045095 keratin filament(GO:0045095)
0.2 2.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 3.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 12.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 4.3 GO:0031528 microvillus membrane(GO:0031528)
0.2 4.0 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 2.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 13.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 4.6 GO:0099738 cell cortex region(GO:0099738)
0.1 11.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 16.6 GO:0016605 PML body(GO:0016605)
0.1 12.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.2 GO:0097440 apical dendrite(GO:0097440)
0.1 1.2 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 4.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 3.0 GO:0005685 U1 snRNP(GO:0005685)
0.1 8.9 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.9 GO:0043034 costamere(GO:0043034)
0.1 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 2.0 GO:0071565 nBAF complex(GO:0071565)
0.1 1.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 1.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 6.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 5.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 3.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.0 GO:0031904 endosome lumen(GO:0031904)
0.1 22.2 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.1 8.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 6.9 GO:0031901 early endosome membrane(GO:0031901)
0.1 5.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 3.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 0.5 GO:0034709 methylosome(GO:0034709)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 17.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 2.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 4.4 GO:0005581 collagen trimer(GO:0005581)
0.0 1.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 7.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 1.2 GO:0001726 ruffle(GO:0001726)
0.0 1.7 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0000922 spindle pole(GO:0000922)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.5 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 11.3 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
3.9 11.8 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
3.2 22.1 GO:0061133 endopeptidase activator activity(GO:0061133)
3.1 9.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
3.1 12.2 GO:0004132 dCMP deaminase activity(GO:0004132)
2.6 10.2 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
2.5 12.7 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
1.9 5.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
1.8 5.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.7 13.6 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
1.6 6.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.6 4.7 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.6 7.8 GO:0015140 malate transmembrane transporter activity(GO:0015140)
1.5 4.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.5 4.4 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.4 7.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
1.4 5.6 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
1.4 5.5 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
1.2 6.1 GO:0070905 serine binding(GO:0070905)
1.2 3.6 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
1.1 6.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
1.1 3.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
1.1 4.4 GO:0043398 HLH domain binding(GO:0043398)
1.1 3.3 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
1.1 8.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.0 5.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
1.0 3.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.0 4.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.0 4.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
1.0 17.5 GO:0001054 RNA polymerase I activity(GO:0001054)
1.0 6.7 GO:0004849 uridine kinase activity(GO:0004849)
0.9 2.8 GO:0002113 interleukin-33 binding(GO:0002113)
0.9 3.7 GO:0043515 kinetochore binding(GO:0043515)
0.9 2.7 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.8 10.1 GO:0031386 protein tag(GO:0031386)
0.8 12.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.8 3.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.8 3.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.8 2.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.8 3.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.8 2.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.7 5.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.7 2.9 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.7 15.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.7 10.8 GO:0008494 translation activator activity(GO:0008494)
0.7 2.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 3.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.7 5.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.6 2.4 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.6 5.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.6 3.9 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.5 16.4 GO:0070717 poly-purine tract binding(GO:0070717)
0.5 3.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.5 8.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.5 3.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 2.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.5 24.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 1.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.5 5.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 1.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.5 9.0 GO:0005537 mannose binding(GO:0005537)
0.4 2.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 5.8 GO:0003993 acid phosphatase activity(GO:0003993) non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 3.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 9.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 2.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.4 2.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.4 2.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 2.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.4 11.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 10.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 12.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 5.8 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.3 4.0 GO:0089720 caspase binding(GO:0089720)
0.3 11.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 12.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 5.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.3 15.9 GO:0000049 tRNA binding(GO:0000049)
0.3 3.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 3.1 GO:0042731 PH domain binding(GO:0042731)
0.3 2.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 10.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 2.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 1.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.3 0.8 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 2.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 12.2 GO:0050699 WW domain binding(GO:0050699)
0.3 6.1 GO:0046961 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 4.2 GO:0051787 misfolded protein binding(GO:0051787)
0.3 3.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 3.0 GO:0000339 RNA cap binding(GO:0000339)
0.2 13.4 GO:0015485 cholesterol binding(GO:0015485)
0.2 5.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 7.2 GO:0070064 proline-rich region binding(GO:0070064)
0.2 4.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 19.9 GO:0032947 protein complex scaffold(GO:0032947)
0.2 3.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 1.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 3.3 GO:0031014 troponin T binding(GO:0031014)
0.2 2.3 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.2 1.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 3.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.1 GO:0097016 L27 domain binding(GO:0097016)
0.2 2.0 GO:0000182 rDNA binding(GO:0000182)
0.2 5.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 10.0 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2 3.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 1.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 3.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 3.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 2.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 0.6 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.2 5.6 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
0.2 3.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 9.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 12.8 GO:0019003 GDP binding(GO:0019003)
0.2 3.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.6 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 1.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 12.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 8.7 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.5 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 6.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.4 GO:0052827 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol pentakisphosphate phosphatase activity(GO:0052827) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 4.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 23.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.0 GO:0031402 sodium ion binding(GO:0031402)
0.1 4.7 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 4.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 3.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 3.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 8.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.3 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 8.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 4.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.3 GO:0008422 beta-glucuronidase activity(GO:0004566) beta-glucosidase activity(GO:0008422)
0.1 1.8 GO:0005123 death receptor binding(GO:0005123)
0.1 6.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 5.0 GO:0004872 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.1 1.3 GO:0030552 cAMP binding(GO:0030552)
0.1 0.8 GO:0016829 lyase activity(GO:0016829)
0.0 4.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.9 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 5.2 GO:0044325 ion channel binding(GO:0044325)
0.0 5.1 GO:0020037 heme binding(GO:0020037)
0.0 2.8 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 2.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 2.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0060589 nucleoside-triphosphatase regulator activity(GO:0060589)
0.0 0.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.7 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 37.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.3 9.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 4.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 5.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 4.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 6.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 2.7 PID S1P S1P2 PATHWAY S1P2 pathway
0.2 11.5 PID ARF6 PATHWAY Arf6 signaling events
0.2 4.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 4.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 4.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 13.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 12.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 14.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 9.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 7.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 11.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 2.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 9.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 6.5 PID BARD1 PATHWAY BARD1 signaling events
0.2 8.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 4.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 6.3 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 20.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.8 PID IFNG PATHWAY IFN-gamma pathway
0.1 4.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 8.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 19.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 7.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.4 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 5.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.0 17.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.9 33.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.8 17.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.6 9.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.6 13.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.5 17.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.5 23.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.5 7.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 10.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.4 34.6 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.4 8.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 8.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 3.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 31.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 9.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.4 6.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 10.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3 4.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 4.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.3 8.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 12.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 22.9 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.3 16.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 2.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 6.6 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 2.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 6.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 3.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 7.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 5.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 5.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.9 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.2 8.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 6.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 11.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 3.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 4.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 7.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 3.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 8.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 8.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 5.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 2.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 3.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 7.9 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 14.3 REACTOME TRANSLATION Genes involved in Translation
0.1 2.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 5.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 1.9 REACTOME KINESINS Genes involved in Kinesins
0.1 2.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 8.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 4.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 5.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway