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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR3C1

Z-value: 2.68

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Transcription factors associated with NR3C1

Gene Symbol Gene ID Gene Info
ENSG00000113580.10 nuclear receptor subfamily 3 group C member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR3C1hg19_v2_chr5_-_142780280_1427804170.101.5e-01Click!

Activity profile of NR3C1 motif

Sorted Z-values of NR3C1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106054659 116.72 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_23237555 88.89 ENST00000390321.2
immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_23248512 83.99 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr14_-_106174960 74.59 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr22_+_23243156 73.46 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr14_-_106692191 56.68 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr22_+_23241661 54.04 ENST00000390322.2
immunoglobulin lambda joining 2
chr6_+_33048222 52.13 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chr14_-_106642049 50.09 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr2_-_89513402 49.77 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr2_-_136875712 45.98 ENST00000241393.3
chemokine (C-X-C motif) receptor 4
chr5_-_149792295 43.85 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74 molecule, major histocompatibility complex, class II invariant chain
chr22_+_23264766 41.92 ENST00000390331.2
immunoglobulin lambda constant 7
chr6_-_33048483 41.71 ENST00000419277.1
major histocompatibility complex, class II, DP alpha 1
chr22_-_17680472 37.29 ENST00000330232.4
cat eye syndrome chromosome region, candidate 1
chr15_-_22448819 34.17 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr14_-_106994333 34.12 ENST00000390624.2
immunoglobulin heavy variable 3-48
chr19_-_10445399 34.04 ENST00000592945.1
intercellular adhesion molecule 3
chr2_-_89278535 33.85 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr14_-_106330458 33.75 ENST00000461719.1
immunoglobulin heavy joining 4
chr14_-_106781017 33.32 ENST00000390612.2
immunoglobulin heavy variable 4-28
chr14_-_107114267 32.05 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr22_+_22712087 31.63 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr10_+_70847852 31.09 ENST00000242465.3
serglycin
chr16_+_32077386 31.09 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_106866934 30.39 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr2_-_89340242 29.95 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr14_-_106805716 29.83 ENST00000438142.2
immunoglobulin heavy variable 4-31
chr2_-_89292422 29.16 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr14_-_106453155 28.24 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr2_-_89545079 28.21 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr14_-_106725723 27.41 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr6_+_32605195 26.35 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr22_+_22681656 26.05 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr15_+_31658349 25.17 ENST00000558844.1
Kruppel-like factor 13
chr2_+_90192768 25.07 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr2_+_89975669 24.79 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr14_-_107219365 24.70 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr14_-_107049312 24.08 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr14_-_106518922 22.97 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr3_+_122044084 22.07 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr2_+_89999259 21.60 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr2_+_89998789 21.58 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr11_+_57365150 21.38 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr12_-_15114492 21.03 ENST00000541546.1
Rho GDP dissociation inhibitor (GDI) beta
chr5_-_172198190 20.58 ENST00000239223.3
dual specificity phosphatase 1
chr15_-_20193370 20.14 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_+_90248739 19.67 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr11_+_117857063 19.28 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
interleukin 10 receptor, alpha
chr2_-_89521942 19.23 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr19_-_36399149 19.17 ENST00000585901.2
ENST00000544690.2
ENST00000424586.3
ENST00000262629.4
ENST00000589517.1
TYRO protein tyrosine kinase binding protein
chr2_+_90198535 19.06 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr22_+_23040274 18.98 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr14_-_107095662 18.80 ENST00000390630.2
immunoglobulin heavy variable 4-61
chr16_+_226658 18.25 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr14_-_106845789 18.17 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr12_-_92539614 18.13 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr14_-_106552755 17.53 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr14_-_106926724 17.45 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr22_+_22676808 16.87 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr21_-_46340770 16.82 ENST00000397854.3
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_-_46340884 16.81 ENST00000302347.5
ENST00000517819.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr15_-_79237433 16.46 ENST00000220166.5
cathepsin H
chr3_-_121379739 15.75 ENST00000428394.2
ENST00000314583.3
hematopoietic cell-specific Lyn substrate 1
chr6_-_41909191 15.74 ENST00000512426.1
ENST00000372987.4
cyclin D3
chr22_+_22764088 15.69 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr14_-_106573756 15.57 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr16_-_33647696 15.30 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein
chr1_-_207095324 15.17 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr4_+_15779901 14.87 ENST00000226279.3
CD38 molecule
chr1_+_22979676 14.69 ENST00000432749.2
ENST00000314933.6
complement component 1, q subcomponent, B chain
chr9_-_97402413 14.66 ENST00000414122.1
fructose-1,6-bisphosphatase 1
chr16_+_33020496 14.37 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr14_-_106668095 14.11 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr16_+_1578674 13.75 ENST00000253934.5
transmembrane protein 204
chr11_+_5710919 13.65 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr14_-_106816253 13.64 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr19_+_42381173 13.29 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr6_+_32605134 13.10 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr12_-_7245125 12.99 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr6_+_29795595 12.78 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
major histocompatibility complex, class I, G
chr19_+_13261216 12.41 ENST00000587885.1
ENST00000292433.3
immediate early response 2
chr19_-_2041159 12.36 ENST00000589441.1
MAP kinase interacting serine/threonine kinase 2
chr2_+_114163945 12.23 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr6_-_31324943 12.07 ENST00000412585.2
ENST00000434333.1
major histocompatibility complex, class I, B
chr16_+_32063311 12.06 ENST00000426099.1
AC142381.1
chr19_-_10450328 11.86 ENST00000160262.5
intercellular adhesion molecule 3
chr19_-_10450287 11.82 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr6_+_32811885 11.74 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr14_-_106733624 11.66 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr19_-_54876558 11.42 ENST00000391742.2
ENST00000434277.2
leukocyte-associated immunoglobulin-like receptor 1
chr14_-_107283278 11.33 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr20_-_62711259 11.16 ENST00000332298.5
regulator of G-protein signaling 19
chr16_+_33006369 11.14 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr12_+_51318513 10.91 ENST00000332160.4
methyltransferase like 7A
chr2_-_158300556 10.86 ENST00000264192.3
cytohesin 1 interacting protein
chr3_-_18480260 10.66 ENST00000454909.2
SATB homeobox 1
chr1_+_22979474 10.51 ENST00000509305.1
complement component 1, q subcomponent, B chain
chr17_-_6983594 10.43 ENST00000571664.1
ENST00000254868.4
C-type lectin domain family 10, member A
chr2_+_89952792 10.41 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr5_-_42811986 10.33 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr15_+_91073111 10.26 ENST00000420329.2
CREB regulated transcription coactivator 3
chr6_+_31783291 9.93 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr6_-_109777128 9.89 ENST00000358807.3
ENST00000358577.3
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr14_-_106478603 9.88 ENST00000390596.2
immunoglobulin heavy variable 4-4
chr1_+_158969752 9.64 ENST00000566111.1
interferon, gamma-inducible protein 16
chr17_-_6983550 9.43 ENST00000576617.1
ENST00000416562.2
C-type lectin domain family 10, member A
chr6_+_32821924 9.28 ENST00000374859.2
ENST00000453265.2
proteasome (prosome, macropain) subunit, beta type, 9
chr15_+_81475047 9.23 ENST00000559388.1
interleukin 16
chr10_+_17270214 9.19 ENST00000544301.1
vimentin
chr1_-_207095212 9.10 ENST00000420007.2
Fas apoptotic inhibitory molecule 3
chr2_+_233925064 9.07 ENST00000359570.5
ENST00000538935.1
inositol polyphosphate-5-phosphatase, 145kDa
chr12_-_51718436 9.03 ENST00000544402.1
bridging integrator 2
chr5_+_49961727 8.97 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
poly (ADP-ribose) polymerase family, member 8
chr19_-_19774473 8.93 ENST00000357324.6
ATPase type 13A1
chr6_+_6588902 8.85 ENST00000230568.4
lymphocyte antigen 86
chr2_-_89568263 8.75 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr9_+_139873264 8.71 ENST00000446677.1
prostaglandin D2 synthase 21kDa (brain)
chr11_+_63304273 8.70 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr20_+_46130619 8.70 ENST00000372004.3
nuclear receptor coactivator 3
chr6_+_31795506 8.63 ENST00000375650.3
heat shock 70kDa protein 1B
chr19_-_36643329 8.61 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr1_+_44115814 8.56 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr1_+_158900568 8.52 ENST00000458222.1
pyrin and HIN domain family, member 1
chrY_+_16168097 8.50 ENST00000250823.4
variable charge, Y-linked 1B
chr14_-_106471723 8.31 ENST00000390595.2
immunoglobulin heavy variable 1-3
chr22_+_37309662 8.26 ENST00000403662.3
ENST00000262825.5
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_+_90458201 8.05 ENST00000603238.1
Uncharacterized protein
chr2_+_27593389 8.02 ENST00000233575.2
ENST00000543024.1
ENST00000537606.1
sorting nexin 17
chr11_-_85376121 7.99 ENST00000527447.1
CREB/ATF bZIP transcription factor
chr19_-_5340730 7.85 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr6_-_99873145 7.69 ENST00000369239.5
ENST00000438806.1
PNN-interacting serine/arginine-rich protein
chr19_-_40440533 7.65 ENST00000221347.6
Fc fragment of IgG binding protein
chr10_-_135090338 7.47 ENST00000415217.3
ADAM metallopeptidase domain 8
chr17_-_19290117 7.44 ENST00000497081.2
microfibrillar-associated protein 4
chr16_+_31366536 7.30 ENST00000562522.1
integrin, alpha X (complement component 3 receptor 4 subunit)
chr17_-_34313685 7.23 ENST00000435911.2
ENST00000586216.1
ENST00000394509.4
chemokine (C-C motif) ligand 14
chr20_+_35201993 7.22 ENST00000373872.4
TGFB-induced factor homeobox 2
chr17_-_76123101 7.15 ENST00000392467.3
transmembrane channel-like 6
chr1_+_233086326 7.11 ENST00000366628.5
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr17_+_7452442 7.10 ENST00000557233.1
tumor necrosis factor (ligand) superfamily, member 12
chr9_+_139874683 7.09 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr8_-_70745575 7.08 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr17_-_3599327 7.03 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr6_-_133079022 6.91 ENST00000525289.1
ENST00000326499.6
vanin 2
chr22_-_39637135 6.82 ENST00000440375.1
platelet-derived growth factor beta polypeptide
chr18_-_59854203 6.80 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
phosphatidylinositol glycan anchor biosynthesis, class N
chr6_-_39693111 6.74 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
kinesin family member 6
chr2_+_90259593 6.66 ENST00000471857.1
immunoglobulin kappa variable 1D-8
chr9_-_35619539 6.61 ENST00000396757.1
CD72 molecule
chr16_+_31366455 6.57 ENST00000268296.4
integrin, alpha X (complement component 3 receptor 4 subunit)
chrX_+_56259316 6.56 ENST00000468660.1
Kruppel-like factor 8
chr6_-_32811771 6.54 ENST00000395339.3
ENST00000374882.3
proteasome (prosome, macropain) subunit, beta type, 8
chr17_-_76124711 6.53 ENST00000306591.7
ENST00000590602.1
transmembrane channel-like 6
chr8_+_38614807 6.41 ENST00000330691.6
ENST00000348567.4
transforming, acidic coiled-coil containing protein 1
chr1_-_207119738 6.41 ENST00000356495.4
polymeric immunoglobulin receptor
chr3_-_151047327 6.36 ENST00000325602.5
purinergic receptor P2Y, G-protein coupled, 13
chr19_-_54876414 6.35 ENST00000474878.1
ENST00000348231.4
leukocyte-associated immunoglobulin-like receptor 1
chr22_+_23046750 6.33 ENST00000390307.2
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr15_-_55700522 6.30 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr17_+_7462103 6.29 ENST00000396545.4
tumor necrosis factor (ligand) superfamily, member 13
chr16_+_68119764 6.28 ENST00000570212.1
ENST00000562926.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr6_-_32821599 6.25 ENST00000354258.4
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr8_-_125740730 6.21 ENST00000354184.4
metastasis suppressor 1
chr13_-_36920872 6.18 ENST00000451493.1
spastic paraplegia 20 (Troyer syndrome)
chrX_+_2609207 6.13 ENST00000381192.3
CD99 molecule
chr12_-_11036844 6.12 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr1_-_153013588 6.12 ENST00000360379.3
small proline-rich protein 2D
chr1_+_90460661 6.08 ENST00000340281.4
ENST00000361911.5
ENST00000370447.3
ENST00000455342.2
zinc finger protein 326
chr8_-_125740514 6.05 ENST00000325064.5
ENST00000518547.1
metastasis suppressor 1
chr5_-_39219705 6.03 ENST00000351578.6
FYN binding protein
chr17_+_7461849 5.88 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chrX_+_64887512 5.81 ENST00000360270.5
moesin
chr3_+_9834179 5.79 ENST00000498623.2
actin related protein 2/3 complex, subunit 4, 20kDa
chr11_+_121447469 5.67 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_+_38179969 5.67 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
myeloid differentiation primary response 88
chr14_+_24641062 5.66 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8 meiotic recombination protein
chr1_+_149230680 5.61 ENST00000443018.1
RP11-403I13.5
chr1_+_24969755 5.60 ENST00000447431.2
ENST00000374389.4
serine/arginine repetitive matrix 1
chr9_-_37034028 5.58 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
paired box 5
chr15_-_55700457 5.52 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr17_-_73975444 5.49 ENST00000293217.5
ENST00000537812.1
acyl-CoA oxidase 1, palmitoyl
chr19_-_52255107 5.42 ENST00000595042.1
ENST00000304748.4
formyl peptide receptor 1
chr17_-_19290483 5.42 ENST00000395592.2
ENST00000299610.4
microfibrillar-associated protein 4
chrX_+_2609317 5.38 ENST00000381187.3
ENST00000381184.1
CD99 molecule
chr6_-_49712147 5.29 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr15_+_99791567 5.28 ENST00000558879.1
ENST00000301981.3
ENST00000422500.2
ENST00000447360.2
ENST00000442993.2
leucine rich repeat containing 28
chr10_+_75545329 5.20 ENST00000604729.1
ENST00000603114.1
zinc finger, SWIM-type containing 8
chr10_-_135090360 5.20 ENST00000486609.1
ENST00000445355.3
ENST00000485491.2
ADAM metallopeptidase domain 8
chr17_+_4843303 5.18 ENST00000571816.1
ring finger protein 167
chr3_-_58200398 5.14 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
deoxyribonuclease I-like 3
chr1_-_182360918 5.13 ENST00000339526.4
glutamate-ammonia ligase
chr17_+_4843413 5.11 ENST00000572430.1
ENST00000262482.6
ring finger protein 167
chrY_-_16098393 5.06 ENST00000250825.4
variable charge, Y-linked
chr17_+_7461781 5.04 ENST00000349228.4
tumor necrosis factor (ligand) superfamily, member 13
chr15_+_74833518 5.03 ENST00000346246.5
AT rich interactive domain 3B (BRIGHT-like)
chr2_-_175499294 5.01 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr5_-_179499086 4.99 ENST00000261947.4
ring finger protein 130
chr7_-_40174201 4.95 ENST00000306984.6
M-phase specific PLK1 interacting protein
chr4_+_7045042 4.93 ENST00000310074.7
ENST00000512388.1
transcriptional adaptor 2B

Network of associatons between targets according to the STRING database.

First level regulatory network of NR3C1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
19.1 191.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
10.4 31.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
8.8 43.9 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
8.7 602.0 GO:0006910 phagocytosis, recognition(GO:0006910)
6.6 46.0 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
5.5 16.5 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
5.3 21.0 GO:0071461 cellular response to redox state(GO:0071461)
4.6 18.6 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
4.6 463.2 GO:0006958 complement activation, classical pathway(GO:0006958)
4.2 12.7 GO:2000412 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309) positive regulation of thymocyte migration(GO:2000412)
3.7 14.7 GO:0005986 sucrose biosynthetic process(GO:0005986)
3.1 15.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
3.0 9.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.8 8.3 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
2.6 7.8 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
2.5 25.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
2.5 24.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
2.4 7.2 GO:0097327 response to antineoplastic agent(GO:0097327)
2.3 6.9 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
2.3 9.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
2.1 12.4 GO:0030035 microspike assembly(GO:0030035)
2.1 24.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.0 7.9 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
1.9 5.8 GO:0019417 sulfur oxidation(GO:0019417)
1.9 5.7 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.9 5.7 GO:0051697 protein delipidation(GO:0051697)
1.9 33.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.7 6.8 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
1.6 6.3 GO:0046967 cytosol to ER transport(GO:0046967)
1.5 6.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.5 6.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
1.5 8.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
1.5 5.8 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.4 5.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
1.4 18.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.4 5.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
1.4 19.3 GO:0045779 negative regulation of bone resorption(GO:0045779)
1.3 6.5 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
1.3 6.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.3 8.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.3 3.8 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.2 8.7 GO:0035624 receptor transactivation(GO:0035624)
1.2 18.3 GO:0015671 oxygen transport(GO:0015671)
1.2 19.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.2 134.9 GO:0031295 T cell costimulation(GO:0031295)
1.2 3.6 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.2 177.5 GO:0002377 immunoglobulin production(GO:0002377)
1.2 3.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
1.1 4.5 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
1.1 21.4 GO:2001204 regulation of osteoclast development(GO:2001204)
1.1 15.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
1.1 4.4 GO:1903238 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) positive regulation of leukocyte tethering or rolling(GO:1903238)
1.1 12.9 GO:0048251 elastic fiber assembly(GO:0048251)
1.1 8.6 GO:0070544 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.1 19.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.1 2.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.0 4.2 GO:0035900 response to isolation stress(GO:0035900)
1.0 9.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
1.0 3.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
1.0 4.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.9 2.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.9 2.8 GO:0070253 somatostatin secretion(GO:0070253)
0.9 7.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 2.5 GO:0051639 actin filament network formation(GO:0051639)
0.8 2.5 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.8 1.7 GO:0007623 circadian rhythm(GO:0007623)
0.8 8.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.8 4.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.8 2.4 GO:0051595 response to methylglyoxal(GO:0051595)
0.8 7.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.8 4.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.8 10.7 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.8 3.8 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.7 4.5 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.7 2.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.7 2.9 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.7 228.2 GO:0002250 adaptive immune response(GO:0002250)
0.7 7.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.7 2.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.7 4.8 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.7 3.4 GO:0015744 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.7 2.6 GO:0000023 maltose metabolic process(GO:0000023)
0.6 1.9 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.6 1.9 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.6 2.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 4.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.6 1.9 GO:0010520 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.6 1.9 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.6 1.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241) positive regulation of chondrocyte proliferation(GO:1902732)
0.6 2.9 GO:0051026 chiasma assembly(GO:0051026)
0.6 12.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.6 8.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.6 1.7 GO:0061055 myotome development(GO:0061055)
0.6 2.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.5 5.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.5 1.6 GO:0042418 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.5 1.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.5 4.2 GO:0016584 nucleosome positioning(GO:0016584)
0.5 6.8 GO:0072520 seminiferous tubule development(GO:0072520)
0.5 2.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.5 2.0 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.5 13.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5 12.9 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.5 2.0 GO:0045064 T-helper 2 cell differentiation(GO:0045064) regulation of T-helper 2 cell differentiation(GO:0045628) positive regulation of T-helper 2 cell differentiation(GO:0045630) Sertoli cell fate commitment(GO:0060010)
0.5 8.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.5 1.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.5 9.5 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.4 27.6 GO:0018149 peptide cross-linking(GO:0018149)
0.4 18.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.4 1.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.4 3.0 GO:0001675 acrosome assembly(GO:0001675)
0.4 9.0 GO:0097320 membrane tubulation(GO:0097320)
0.4 5.1 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.4 3.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.4 2.9 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.4 3.7 GO:0043587 tongue morphogenesis(GO:0043587)
0.4 2.9 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.4 2.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.4 3.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.4 4.4 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.4 1.6 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.4 1.2 GO:0021558 trochlear nerve development(GO:0021558)
0.4 1.2 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.4 2.7 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.4 9.8 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.4 4.8 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4 4.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.4 1.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.4 1.5 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.4 3.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 10.3 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.4 1.1 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.4 5.0 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.4 1.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.3 6.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.3 5.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 5.8 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.3 1.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 4.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.0 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.3 0.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 2.5 GO:0042908 xenobiotic transport(GO:0042908)
0.3 0.6 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.3 1.6 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.3 1.2 GO:0097338 response to clozapine(GO:0097338)
0.3 1.5 GO:0060214 stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
0.3 2.5 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.3 2.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.8 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.3 2.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.3 9.5 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.3 1.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 2.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.3 2.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3 0.6 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.3 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 2.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.3 4.1 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.3 5.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 3.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.3 1.1 GO:0016553 base conversion or substitution editing(GO:0016553) cytidine to uridine editing(GO:0016554)
0.3 2.7 GO:0071313 cellular response to caffeine(GO:0071313)
0.3 6.9 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3 15.6 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.3 9.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 8.4 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.3 5.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 1.0 GO:0008272 sulfate transport(GO:0008272)
0.3 11.3 GO:0070206 protein trimerization(GO:0070206)
0.2 14.6 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.2 6.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 2.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 1.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 5.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.1 GO:1990253 cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.2 43.6 GO:0006909 phagocytosis(GO:0006909)
0.2 0.9 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 0.4 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 1.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 2.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.2 8.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 1.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.5 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.2 3.2 GO:0007224 smoothened signaling pathway(GO:0007224)
0.2 0.6 GO:0036343 psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.2 2.2 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.2 0.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 7.4 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.2 1.6 GO:0030916 otic vesicle formation(GO:0030916) pronephros development(GO:0048793)
0.2 0.9 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.8 GO:0048318 axial mesoderm development(GO:0048318)
0.2 1.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.2 1.1 GO:0031053 primary miRNA processing(GO:0031053)
0.1 2.1 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 1.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 2.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1 1.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 3.8 GO:0006379 mRNA cleavage(GO:0006379)
0.1 6.1 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 2.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 1.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 0.8 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.1 1.9 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.8 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.2 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.1 7.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.1 1.1 GO:0006477 protein sulfation(GO:0006477)
0.1 0.5 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 5.4 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.6 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 1.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 2.0 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.1 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 2.0 GO:0031297 replication fork processing(GO:0031297)
0.1 1.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.2 GO:0043116 negative regulation of vascular permeability(GO:0043116) negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 2.2 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 13.3 GO:0050807 regulation of synapse organization(GO:0050807)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 6.5 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 3.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.1 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.1 1.1 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 2.8 GO:0042073 intraciliary transport(GO:0042073)
0.1 3.3 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.0 GO:0045008 depyrimidination(GO:0045008)
0.1 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.4 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 4.2 GO:0006968 cellular defense response(GO:0006968)
0.1 0.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 0.5 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.5 GO:0002027 regulation of heart rate(GO:0002027)
0.1 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.1 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.2 GO:0032773 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 2.4 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 4.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.9 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 3.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 4.7 GO:0006672 ceramide metabolic process(GO:0006672)
0.1 1.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.5 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042) regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 1.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.3 GO:0046618 drug export(GO:0046618)
0.1 0.1 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.1 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 1.0 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.1 6.4 GO:0006338 chromatin remodeling(GO:0006338)
0.1 0.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 1.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.7 GO:0019915 lipid storage(GO:0019915)
0.0 2.0 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 4.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.5 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.8 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 2.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.2 GO:0002335 mature B cell differentiation involved in immune response(GO:0002313) marginal zone B cell differentiation(GO:0002315) mature B cell differentiation(GO:0002335)
0.0 1.1 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 1.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0015824 proline transport(GO:0015824)
0.0 1.4 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.4 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.2 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.9 GO:0007420 brain development(GO:0007420)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0006811 ion transport(GO:0006811)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.3 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.1 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.2 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 2.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 1.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0002062 chondrocyte differentiation(GO:0002062)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
63.8 191.3 GO:0071746 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
12.8 601.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
8.4 177.1 GO:0042613 MHC class II protein complex(GO:0042613)
6.7 33.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
5.0 25.2 GO:0005602 complement component C1 complex(GO:0005602)
4.6 18.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
4.2 12.7 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
3.4 27.6 GO:1990111 spermatoproteasome complex(GO:1990111)
2.3 24.9 GO:0042612 MHC class I protein complex(GO:0042612)
2.1 16.5 GO:0097208 alveolar lamellar body(GO:0097208)
2.0 6.1 GO:0044609 DBIRD complex(GO:0044609)
2.0 360.4 GO:0072562 blood microparticle(GO:0072562)
1.9 13.3 GO:0019815 B cell receptor complex(GO:0019815)
1.9 5.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.8 10.8 GO:0042825 TAP complex(GO:0042825)
1.7 6.9 GO:0005797 Golgi medial cisterna(GO:0005797)
1.4 29.3 GO:0042588 zymogen granule(GO:0042588)
1.3 5.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.3 12.9 GO:0071953 elastic fiber(GO:0071953)
1.1 4.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.1 9.7 GO:0070652 HAUS complex(GO:0070652)
0.9 8.5 GO:0061574 ASAP complex(GO:0061574)
0.7 2.9 GO:0005713 recombination nodule(GO:0005713)
0.7 4.8 GO:0097165 nuclear stress granule(GO:0097165)
0.7 6.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.7 3.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.7 2.7 GO:0030314 junctional membrane complex(GO:0030314)
0.6 11.6 GO:0097386 glial cell projection(GO:0097386)
0.6 5.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.6 4.4 GO:0042788 polysomal ribosome(GO:0042788)
0.5 4.4 GO:0031672 A band(GO:0031672)
0.5 3.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 7.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 9.0 GO:0001891 phagocytic cup(GO:0001891)
0.4 1.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.4 13.9 GO:0008305 integrin complex(GO:0008305)
0.4 1.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.4 18.4 GO:0001533 cornified envelope(GO:0001533)
0.3 2.4 GO:0061700 GATOR2 complex(GO:0061700)
0.3 4.8 GO:0036038 MKS complex(GO:0036038)
0.3 5.3 GO:0030914 STAGA complex(GO:0030914)
0.3 4.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 3.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.3 24.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.3 31.3 GO:0035579 specific granule membrane(GO:0035579)
0.3 2.4 GO:0005796 Golgi lumen(GO:0005796)
0.3 13.0 GO:0016235 aggresome(GO:0016235)
0.2 1.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 2.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 3.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 3.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 4.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 13.3 GO:0015030 Cajal body(GO:0015030)
0.2 10.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.2 1.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 2.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 4.3 GO:0034706 sodium channel complex(GO:0034706)
0.2 4.2 GO:0042101 T cell receptor complex(GO:0042101)
0.2 0.8 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 3.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.2 8.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 4.8 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 1.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 211.2 GO:0005615 extracellular space(GO:0005615)
0.1 31.7 GO:0005770 late endosome(GO:0005770)
0.1 5.6 GO:0031201 SNARE complex(GO:0031201)
0.1 13.0 GO:0005769 early endosome(GO:0005769)
0.1 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.8 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 16.8 GO:0016605 PML body(GO:0016605)
0.1 1.2 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.5 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 5.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 6.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 6.3 GO:0043195 terminal bouton(GO:0043195)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.8 GO:0005794 Golgi apparatus(GO:0005794)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 2.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 2.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 10.2 GO:0001726 ruffle(GO:0001726)
0.1 3.8 GO:0030120 vesicle coat(GO:0030120)
0.1 4.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.5 GO:0097361 CIA complex(GO:0097361)
0.1 1.1 GO:0043235 receptor complex(GO:0043235)
0.1 6.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 6.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.3 GO:0031526 brush border membrane(GO:0031526)
0.1 1.5 GO:0032420 stereocilium(GO:0032420)
0.1 4.5 GO:0005811 lipid particle(GO:0005811)
0.1 9.0 GO:0001650 fibrillar center(GO:0001650)
0.1 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.0 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 1.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 5.3 GO:0031410 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.1 0.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.8 GO:0005657 replication fork(GO:0005657)
0.1 6.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.7 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 2.0 GO:0016460 myosin II complex(GO:0016460)
0.0 3.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0005856 cytoskeleton(GO:0005856)
0.0 1.8 GO:0030426 growth cone(GO:0030426)
0.0 3.6 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 3.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.1 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 16.0 GO:0005912 adherens junction(GO:0005912)
0.0 2.4 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.9 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 793.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
8.8 43.9 GO:0042289 MHC class II protein binding(GO:0042289)
6.9 20.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
6.2 81.2 GO:0032395 MHC class II receptor activity(GO:0032395)
5.0 14.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
4.8 33.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
4.8 830.0 GO:0003823 antigen binding(GO:0003823)
4.2 46.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
3.9 15.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
3.7 14.7 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
3.1 18.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
3.0 9.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
2.8 19.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
2.8 8.3 GO:0004914 interleukin-5 receptor activity(GO:0004914)
2.4 7.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.3 9.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
2.3 6.8 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
2.1 21.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.1 16.5 GO:0070324 thyroid hormone binding(GO:0070324)
1.9 5.6 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
1.5 6.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
1.5 9.2 GO:1990254 keratin filament binding(GO:1990254)
1.5 4.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.4 7.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
1.4 18.3 GO:0005344 oxygen transporter activity(GO:0005344)
1.4 4.2 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
1.4 5.4 GO:0005124 scavenger receptor binding(GO:0005124)
1.4 4.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.1 8.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.1 6.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.1 4.3 GO:0017040 ceramidase activity(GO:0017040)
1.1 4.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.0 7.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.0 2.9 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
1.0 8.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.9 3.8 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.9 4.5 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.9 3.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.9 3.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.8 5.0 GO:0004447 iodide peroxidase activity(GO:0004447)
0.8 15.1 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.8 7.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.8 3.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.7 6.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.7 10.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.7 6.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.7 2.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 3.4 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.7 4.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.7 3.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.7 2.6 GO:0016160 amylase activity(GO:0016160) maltose alpha-glucosidase activity(GO:0032450)
0.6 1.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 4.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.6 4.5 GO:0001727 lipid kinase activity(GO:0001727)
0.6 7.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.6 1.9 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.6 29.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.6 3.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.6 3.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 17.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 1.6 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.5 1.6 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.5 15.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 1.6 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.5 3.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.5 7.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.5 8.3 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.5 2.4 GO:0070728 leucine binding(GO:0070728)
0.4 9.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 1.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 2.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.4 1.1 GO:0015616 DNA translocase activity(GO:0015616)
0.4 3.4 GO:0051787 misfolded protein binding(GO:0051787)
0.4 2.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.4 1.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 1.7 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 1.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.3 4.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 31.7 GO:0005518 collagen binding(GO:0005518)
0.3 1.0 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.3 1.9 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.3 6.4 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 4.4 GO:0008097 5S rRNA binding(GO:0008097)
0.3 7.5 GO:0071949 FAD binding(GO:0071949)
0.3 8.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 4.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 2.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 1.4 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3 5.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 11.7 GO:0003785 actin monomer binding(GO:0003785)
0.3 2.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.3 2.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 9.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.3 15.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 6.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 3.4 GO:0043422 protein kinase B binding(GO:0043422)
0.2 2.5 GO:0032052 bile acid binding(GO:0032052)
0.2 9.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 1.2 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.7 GO:0050473 hepoxilin-epoxide hydrolase activity(GO:0047977) arachidonate 15-lipoxygenase activity(GO:0050473)
0.2 4.8 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 1.7 GO:0043559 insulin binding(GO:0043559)
0.2 1.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 8.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 1.6 GO:0001515 opioid peptide activity(GO:0001515)
0.2 2.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 7.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 1.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 2.8 GO:0031005 filamin binding(GO:0031005)
0.2 0.9 GO:0034618 arginine binding(GO:0034618)
0.2 3.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 2.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 12.6 GO:0043621 protein self-association(GO:0043621)
0.2 0.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 1.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 6.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 32.8 GO:0005178 integrin binding(GO:0005178)
0.2 3.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 14.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 4.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.6 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 3.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 3.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 4.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.9 GO:0030983 mismatched DNA binding(GO:0030983)
0.2 4.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 4.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 6.8 GO:0070412 R-SMAD binding(GO:0070412)
0.2 41.6 GO:0030674 protein binding, bridging(GO:0030674)
0.2 3.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 3.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 0.5 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.2 2.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 0.6 GO:0001855 complement component C4b binding(GO:0001855)
0.2 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 5.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.0 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 15.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 36.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 0.9 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 17.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 5.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 3.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 6.9 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.8 GO:0000150 recombinase activity(GO:0000150)
0.1 2.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.2 GO:0089720 caspase binding(GO:0089720)
0.1 31.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 18.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 3.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.1 3.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 2.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 6.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 5.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 1.7 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 2.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.2 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.6 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 2.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.0 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 109.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.2 56.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.6 37.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.6 31.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.5 83.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.5 9.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.5 43.5 PID BCR 5PATHWAY BCR signaling pathway
0.5 2.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.5 9.9 PID IL5 PATHWAY IL5-mediated signaling events
0.5 4.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.4 4.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.4 15.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 24.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.4 3.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 12.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 16.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.3 13.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 7.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 3.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 17.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 5.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 53.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 6.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 6.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 6.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 1.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 5.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 3.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 3.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 6.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 7.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 5.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.9 PID FOXO PATHWAY FoxO family signaling
0.1 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 7.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 11.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.7 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 6.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 46.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
6.3 137.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
2.5 24.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.8 20.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.4 116.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.2 23.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.0 5.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.9 4.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6 9.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.5 12.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.4 22.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4 3.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.4 3.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.4 10.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.4 9.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 6.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.3 4.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3 4.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 4.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 5.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 6.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.3 12.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 9.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 1.1 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.3 8.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 2.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 5.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 4.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 28.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 7.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 2.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 17.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 2.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 13.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 12.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 5.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 4.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 5.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 7.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 2.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 4.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 3.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 5.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 3.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 8.0 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 4.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 3.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 5.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 5.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.6 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.1 1.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 4.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 11.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 10.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 9.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 4.6 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 7.8 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 4.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling