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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for NR5A2

Z-value: 1.90

Motif logo

Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
ENSG00000116833.9 nuclear receptor subfamily 5 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v2_chr1_+_199996702_1999967320.322.0e-06Click!

Activity profile of NR5A2 motif

Sorted Z-values of NR5A2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_21491477 65.98 ENST00000298684.5
ENST00000557169.1
ENST00000553563.1
NDRG family member 2
chr14_-_21492251 58.22 ENST00000554398.1
NDRG family member 2
chr14_-_21492113 57.00 ENST00000554094.1
NDRG family member 2
chr16_+_56623433 36.02 ENST00000570176.1
metallothionein 3
chrX_+_103031421 35.60 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr8_-_110704014 35.09 ENST00000529190.1
ENST00000422135.1
ENST00000419099.1
syntabulin (syntaxin-interacting)
chrX_+_103031758 34.81 ENST00000303958.2
ENST00000361621.2
proteolipid protein 1
chr2_+_220491973 28.49 ENST00000358055.3
solute carrier family 4 (anion exchanger), member 3
chr16_+_226658 28.47 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr14_-_21490958 26.64 ENST00000554104.1
NDRG family member 2
chr8_+_21911054 25.20 ENST00000519850.1
ENST00000381470.3
dematin actin binding protein
chr5_-_176056974 24.53 ENST00000510387.1
ENST00000506696.1
synuclein, beta
chr11_-_790060 23.46 ENST00000330106.4
cell cycle exit and neuronal differentiation 1
chr2_+_220492116 21.74 ENST00000373760.2
solute carrier family 4 (anion exchanger), member 3
chr3_+_133465228 21.06 ENST00000482271.1
ENST00000264998.3
transferrin
chrX_-_49056635 20.96 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
synaptophysin
chr14_-_21491305 20.82 ENST00000554531.1
NDRG family member 2
chr19_-_36643329 19.62 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr3_-_58613323 19.31 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr14_-_60337684 18.26 ENST00000267484.5
reticulon 1
chr17_-_8066250 17.15 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr11_-_111781454 16.86 ENST00000533280.1
crystallin, alpha B
chr22_-_39239987 16.86 ENST00000333039.2
neuronal pentraxin receptor
chr6_-_52860171 15.57 ENST00000370963.4
glutathione S-transferase alpha 4
chr1_-_149889382 15.41 ENST00000369145.1
ENST00000369146.3
synaptic vesicle glycoprotein 2A
chr7_+_29519486 14.94 ENST00000409041.4
chimerin 2
chr8_-_110703819 14.79 ENST00000532779.1
ENST00000534578.1
syntabulin (syntaxin-interacting)
chr11_-_111781554 14.75 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr22_-_37213045 14.54 ENST00000406910.2
ENST00000417718.2
parvalbumin
chr20_-_62130474 14.53 ENST00000217182.3
eukaryotic translation elongation factor 1 alpha 2
chr7_+_29519662 14.35 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
chimerin 2
chr2_+_220492373 14.26 ENST00000317151.3
solute carrier family 4 (anion exchanger), member 3
chr22_+_19710468 14.22 ENST00000366425.3
glycoprotein Ib (platelet), beta polypeptide
chr19_+_19322758 14.19 ENST00000252575.6
neurocan
chr15_+_43985084 13.99 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr17_-_56606705 13.98 ENST00000317268.3
septin 4
chr5_+_71403061 13.97 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr17_-_56606664 13.88 ENST00000580844.1
septin 4
chr22_-_29711704 13.73 ENST00000216101.6
RAS-like, family 10, member A
chr15_+_43886057 13.69 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
creatine kinase, mitochondrial 1B
chr17_-_56606639 13.69 ENST00000579371.1
septin 4
chr12_+_130554803 13.68 ENST00000535487.1
RP11-474D1.2
chr15_+_43985725 13.68 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr10_-_75634219 13.56 ENST00000305762.7
calcium/calmodulin-dependent protein kinase II gamma
chr6_-_34360413 13.51 ENST00000607016.1
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr6_+_111580508 13.11 ENST00000368847.4
KIAA1919
chr22_-_29711645 13.10 ENST00000401450.3
RAS-like, family 10, member A
chr12_-_50290839 12.90 ENST00000552863.1
Fas apoptotic inhibitory molecule 2
chr20_+_37434329 12.88 ENST00000299824.1
ENST00000373331.2
protein phosphatase 1, regulatory subunit 16B
chr15_+_43885252 12.60 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr7_-_105029812 12.60 ENST00000482897.1
SRSF protein kinase 2
chr2_+_220492287 12.51 ENST00000273063.6
ENST00000373762.3
solute carrier family 4 (anion exchanger), member 3
chr3_-_10547333 12.46 ENST00000383800.4
ATPase, Ca++ transporting, plasma membrane 2
chr12_-_56882136 12.45 ENST00000311966.4
glutaminase 2 (liver, mitochondrial)
chr4_-_681114 12.37 ENST00000503156.1
major facilitator superfamily domain containing 7
chr1_-_2323140 12.26 ENST00000378531.3
ENST00000378529.3
MORN repeat containing 1
chr19_+_5623186 12.15 ENST00000538656.1
scaffold attachment factor B
chr10_-_75634260 12.07 ENST00000372765.1
ENST00000351293.3
calcium/calmodulin-dependent protein kinase II gamma
chr20_-_48532019 11.95 ENST00000289431.5
spermatogenesis associated 2
chr22_-_37213554 11.85 ENST00000443735.1
parvalbumin
chr22_+_32149927 11.79 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEP domain containing 5
chr7_-_87104963 11.76 ENST00000359206.3
ENST00000358400.3
ENST00000265723.4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr1_+_169077172 11.50 ENST00000499679.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_+_110718921 11.40 ENST00000308664.6
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr3_-_10547192 11.22 ENST00000360273.2
ENST00000343816.4
ATPase, Ca++ transporting, plasma membrane 2
chr10_-_75634326 11.21 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
calcium/calmodulin-dependent protein kinase II gamma
chr7_+_45613958 11.21 ENST00000297323.7
adenylate cyclase 1 (brain)
chr8_+_136469684 11.12 ENST00000355849.5
KH domain containing, RNA binding, signal transduction associated 3
chr1_+_202995611 11.11 ENST00000367240.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr19_+_41284121 11.10 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B, member RAS oncogene family
chr17_-_27503770 11.10 ENST00000533112.1
myosin XVIIIA
chr8_+_86376081 10.99 ENST00000285379.5
carbonic anhydrase II
chr1_+_84609944 10.97 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_10068095 10.87 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr17_-_8066843 10.78 ENST00000404970.3
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr9_+_131873227 10.73 ENST00000358994.4
ENST00000455292.1
protein phosphatase 2A activator, regulatory subunit 4
chr22_+_40390930 10.37 ENST00000333407.6
family with sequence similarity 83, member F
chr13_+_113622757 10.36 ENST00000375604.2
MCF.2 cell line derived transforming sequence-like
chr7_+_99156314 10.23 ENST00000425063.1
ENST00000493277.1
zinc finger protein 655
chr8_-_67341208 10.13 ENST00000499642.1
RP11-346I3.4
chr10_-_50970322 10.01 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr15_+_43809797 9.92 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr1_-_241520525 9.81 ENST00000366565.1
regulator of G-protein signaling 7
chr17_-_73844722 9.60 ENST00000586257.1
WW domain binding protein 2
chr1_+_19923454 9.54 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr12_-_49393092 9.46 ENST00000421952.2
dendrin
chr19_+_589893 9.40 ENST00000251287.2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_-_38604398 9.31 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
atlastin GTPase 2
chr17_-_76778339 9.29 ENST00000591455.1
ENST00000446868.3
ENST00000361101.4
ENST00000589296.1
cytohesin 1
chr11_-_64512273 9.22 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr5_+_141303373 9.13 ENST00000432126.2
ENST00000194118.4
KIAA0141
chr1_+_1260147 9.05 ENST00000343938.4
glycolipid transfer protein domain containing 1
chr7_+_99156434 9.02 ENST00000424881.1
ENST00000440391.1
ENST00000394163.2
zinc finger protein 655
chr13_+_113622810 8.93 ENST00000397030.1
MCF.2 cell line derived transforming sequence-like
chr4_-_5894777 8.89 ENST00000324989.7
collapsin response mediator protein 1
chr11_-_9025541 8.84 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
nuclear receptor interacting protein 3
chr1_-_200992827 8.75 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr10_-_50970382 8.73 ENST00000419399.1
ENST00000432695.1
oxoglutarate dehydrogenase-like
chr3_-_10749696 8.72 ENST00000397077.1
ATPase, Ca++ transporting, plasma membrane 2
chr7_+_156742399 8.64 ENST00000275820.3
nucleolar protein with MIF4G domain 1
chr3_-_50605077 8.55 ENST00000426034.1
ENST00000441239.1
chromosome 3 open reading frame 18
chr22_-_44708731 8.36 ENST00000381176.4
KIAA1644
chr4_+_7045042 8.23 ENST00000310074.7
ENST00000512388.1
transcriptional adaptor 2B
chr12_-_12491608 8.20 ENST00000545735.1
MANSC domain containing 1
chr7_+_29237354 8.13 ENST00000546235.1
chimerin 2
chr1_+_27719148 8.03 ENST00000374024.3
G protein-coupled receptor 3
chr12_+_6644443 8.02 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr16_-_2264779 7.93 ENST00000333503.7
phosphoglycolate phosphatase
chr5_+_66254698 7.90 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
microtubule associated serine/threonine kinase family member 4
chr12_+_57857475 7.83 ENST00000528467.1
GLI family zinc finger 1
chr22_+_20104947 7.79 ENST00000402752.1
RAN binding protein 1
chr6_+_134758827 7.66 ENST00000431422.1
long intergenic non-protein coding RNA 1010
chr3_+_4535155 7.58 ENST00000544951.1
inositol 1,4,5-trisphosphate receptor, type 1
chr1_-_241520385 7.57 ENST00000366564.1
regulator of G-protein signaling 7
chr16_+_67694849 7.51 ENST00000602551.1
ENST00000458121.2
ENST00000219255.3
par-6 family cell polarity regulator alpha
chr22_+_46546494 7.51 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
peroxisome proliferator-activated receptor alpha
chr12_+_120875887 7.43 ENST00000229379.2
cytochrome c oxidase subunit VIa polypeptide 1
chr16_+_19729586 7.38 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQ motif containing K
chr11_-_118047376 7.35 ENST00000278947.5
sodium channel, voltage-gated, type II, beta subunit
chr6_-_27782548 7.25 ENST00000333151.3
histone cluster 1, H2aj
chr12_-_117537240 7.25 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
tescalcin
chr14_+_75761099 7.21 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5
chr15_-_78526855 7.21 ENST00000541759.1
ENST00000558130.1
acyl-CoA synthetase bubblegum family member 1
chr12_+_48513570 7.18 ENST00000551804.1
phosphofructokinase, muscle
chr20_-_45280066 7.17 ENST00000279027.4
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr6_-_27806117 7.16 ENST00000330180.2
histone cluster 1, H2ak
chr10_-_101190202 7.13 ENST00000543866.1
ENST00000370508.5
glutamic-oxaloacetic transaminase 1, soluble
chr14_-_31889782 7.05 ENST00000543095.2
HEAT repeat containing 5A
chr11_-_3862059 7.05 ENST00000396978.1
ras homolog family member G
chr6_-_33285505 7.01 ENST00000431845.2
zinc finger and BTB domain containing 22
chr5_+_80529104 6.93 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
creatine kinase, mitochondrial 2 (sarcomeric)
chr5_-_218251 6.93 ENST00000296824.3
coiled-coil domain containing 127
chr20_-_45280091 6.88 ENST00000396360.1
ENST00000435032.1
ENST00000413164.2
ENST00000372121.1
ENST00000339636.3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr3_+_4535025 6.83 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
inositol 1,4,5-trisphosphate receptor, type 1
chr17_+_48585958 6.82 ENST00000436259.2
MYCBP associated protein
chr2_-_100939195 6.79 ENST00000393437.3
LON peptidase N-terminal domain and ring finger 2
chr16_+_2588012 6.77 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chr3_-_49466686 6.73 ENST00000273598.3
ENST00000436744.2
nicolin 1
chr10_-_104179682 6.70 ENST00000406432.1
pleckstrin and Sec7 domain containing
chr2_-_97304009 6.69 ENST00000431828.1
ENST00000435669.1
ENST00000440133.1
ENST00000448075.1
KAT8 regulatory NSL complex subunit 3
chr17_+_30814707 6.67 ENST00000584792.1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_+_58694396 6.65 ENST00000326804.4
ENST00000345813.3
ENST00000424679.2
zinc finger protein 274
chr6_+_88757507 6.60 ENST00000237201.1
sperm acrosome associated 1
chr16_+_15031300 6.57 ENST00000328085.6
nuclear pore complex interacting protein family, member A1
chr19_+_42381173 6.54 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr1_-_149858227 6.53 ENST00000369155.2
histone cluster 2, H2be
chr1_+_207226574 6.53 ENST00000367080.3
ENST00000367079.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr12_-_9268707 6.45 ENST00000318602.7
alpha-2-macroglobulin
chr20_+_32077880 6.43 ENST00000342704.6
ENST00000375279.2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr18_-_51750948 6.41 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr2_-_97304105 6.41 ENST00000599854.1
ENST00000441706.2
KAT8 regulatory NSL complex subunit 3
chr4_-_170947522 6.41 ENST00000361618.3
microfibrillar-associated protein 3-like
chr19_+_48773337 6.39 ENST00000595607.1
zinc finger protein 114
chr3_-_183735731 6.36 ENST00000334444.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr22_+_30792980 6.32 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14-like 2 (S. cerevisiae)
chr1_-_160492994 6.25 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAM family member 6
chr1_+_15764931 6.24 ENST00000375949.4
ENST00000375943.2
chymotrypsin C (caldecrin)
chr3_-_122512619 6.23 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr7_-_158622210 6.22 ENST00000251527.5
extended synaptotagmin-like protein 2
chr5_-_134914673 6.22 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr12_+_48513009 6.18 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
phosphofructokinase, muscle
chr2_-_27718052 6.13 ENST00000264703.3
fibronectin type III domain containing 4
chr22_+_38035459 6.12 ENST00000357436.4
SH3-domain binding protein 1
chr1_-_203155868 6.12 ENST00000255409.3
chitinase 3-like 1 (cartilage glycoprotein-39)
chr5_+_140753444 6.11 ENST00000517434.1
protocadherin gamma subfamily A, 6
chr10_-_124768300 6.11 ENST00000368886.5
IKAROS family zinc finger 5 (Pegasus)
chr11_+_63742050 6.08 ENST00000314133.3
ENST00000535431.1
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr16_+_28875126 6.05 ENST00000359285.5
ENST00000538342.1
SH2B adaptor protein 1
chrX_+_30671476 6.01 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
glycerol kinase
chr11_+_1411503 5.98 ENST00000526678.1
BR serine/threonine kinase 2
chr20_+_54933971 5.95 ENST00000371384.3
ENST00000437418.1
family with sequence similarity 210, member B
chr20_+_1875942 5.95 ENST00000358771.4
signal-regulatory protein alpha
chr11_-_64511789 5.94 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr20_+_53092123 5.81 ENST00000262593.5
docking protein 5
chr1_+_203096831 5.76 ENST00000337894.4
adenosine A1 receptor
chr9_+_103235365 5.76 ENST00000374879.4
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_137113604 5.74 ENST00000359015.4
mitogen-activated protein kinase kinase kinase 5
chr3_-_49158312 5.72 ENST00000398892.3
ENST00000453664.1
ENST00000398888.2
ubiquitin specific peptidase 19
chr5_-_88179017 5.68 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
myocyte enhancer factor 2C
chrX_-_43741594 5.67 ENST00000536181.1
ENST00000378069.4
monoamine oxidase B
chr5_+_65018017 5.55 ENST00000380985.5
ENST00000502464.1
neurolysin (metallopeptidase M3 family)
chr16_+_3451184 5.53 ENST00000575752.1
ENST00000571936.1
ENST00000344823.5
zinc finger protein 174
chr22_+_30792846 5.52 ENST00000312932.9
ENST00000428195.1
SEC14-like 2 (S. cerevisiae)
chr1_+_29138654 5.51 ENST00000234961.2
opioid receptor, delta 1
chr14_+_91580732 5.49 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
chromosome 14 open reading frame 159
chrX_+_48681768 5.48 ENST00000430858.1
histone deacetylase 6
chr16_+_8814563 5.46 ENST00000425191.2
ENST00000569156.1
4-aminobutyrate aminotransferase
chr1_+_44584522 5.43 ENST00000372299.3
Kruppel-like factor 17
chr20_-_18447667 5.33 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
double zinc ribbon and ankyrin repeat domains 1
chr1_+_29213678 5.33 ENST00000347529.3
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr21_+_34697258 5.31 ENST00000442071.1
ENST00000442357.2
interferon (alpha, beta and omega) receptor 1
chr6_+_27100811 5.29 ENST00000359193.2
histone cluster 1, H2ag
chrX_+_22056165 5.27 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr9_-_127269661 5.23 ENST00000373588.4
nuclear receptor subfamily 5, group A, member 1
chr22_+_23412479 5.19 ENST00000248996.4
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr17_+_66539369 5.18 ENST00000600820.1
Uncharacterized protein; cDNA FLJ45097 fis, clone BRAWH3031054
chr5_+_34929677 5.11 ENST00000342382.4
ENST00000382021.2
ENST00000303525.7
DnaJ (Hsp40) homolog, subfamily C, member 21
chr5_-_88178964 5.11 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
myocyte enhancer factor 2C
chr11_+_10472223 5.00 ENST00000396554.3
ENST00000524866.1
adenosine monophosphate deaminase 3
chr1_-_20834586 4.99 ENST00000264198.3
mitochondrial E3 ubiquitin protein ligase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NR5A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.3 228.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
12.0 36.0 GO:2000296 cadmium ion homeostasis(GO:0055073) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
8.3 41.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
4.7 23.5 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
4.5 13.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
4.3 12.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.2 25.2 GO:0070560 protein secretion by platelet(GO:0070560)
4.1 69.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
4.0 27.9 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
3.9 11.8 GO:0097327 response to antineoplastic agent(GO:0097327) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
3.9 11.7 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
3.8 15.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
3.7 11.1 GO:1903028 positive regulation of opsonization(GO:1903028)
3.7 11.0 GO:0042938 dipeptide transport(GO:0042938)
3.5 14.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
3.5 21.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
3.1 34.6 GO:0006600 creatine metabolic process(GO:0006600)
3.0 3.0 GO:0043457 regulation of cellular respiration(GO:0043457)
3.0 8.9 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
2.9 14.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
2.9 11.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
2.8 8.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
2.7 13.5 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
2.7 10.8 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.5 12.6 GO:0035063 nuclear speck organization(GO:0035063)
2.5 12.5 GO:0006543 glutamine catabolic process(GO:0006543)
2.4 9.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.3 7.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.3 20.9 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
2.3 9.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
2.2 6.7 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
2.2 11.0 GO:0097338 response to clozapine(GO:0097338)
2.0 8.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
2.0 29.7 GO:0015671 oxygen transport(GO:0015671)
2.0 7.8 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
1.9 36.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.9 5.8 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
1.9 21.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.9 11.3 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.9 7.5 GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
1.9 9.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
1.9 5.6 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.8 5.5 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
1.8 10.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.8 31.6 GO:0007021 tubulin complex assembly(GO:0007021)
1.6 9.4 GO:0071321 cellular response to cGMP(GO:0071321)
1.5 15.0 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.5 6.0 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.5 3.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
1.5 78.3 GO:0015701 bicarbonate transport(GO:0015701)
1.5 11.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.5 7.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.5 4.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
1.5 4.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.4 4.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
1.4 4.3 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
1.4 9.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.4 6.8 GO:0032971 regulation of muscle filament sliding(GO:0032971)
1.3 6.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.3 3.9 GO:0021571 rhombomere 5 development(GO:0021571)
1.3 5.2 GO:0007538 primary sex determination(GO:0007538)
1.2 11.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
1.2 3.7 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
1.2 7.3 GO:0046684 response to pyrethroid(GO:0046684)
1.2 3.6 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.1 4.5 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
1.1 5.7 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.1 4.5 GO:2000314 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
1.1 3.3 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.1 3.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
1.1 5.3 GO:1904383 response to sodium phosphate(GO:1904383)
1.0 5.2 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
1.0 4.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.0 19.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.9 2.8 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.9 12.9 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.9 7.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.9 20.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.9 2.7 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.9 6.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.9 2.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.9 13.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.9 2.6 GO:0007497 posterior midgut development(GO:0007497)
0.9 6.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.9 2.6 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.8 17.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.8 7.5 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.8 5.0 GO:0006196 AMP catabolic process(GO:0006196)
0.8 18.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.8 4.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.8 2.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.8 2.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.8 14.5 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.7 3.0 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.7 3.6 GO:0046968 peptide antigen transport(GO:0046968)
0.7 3.6 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.7 5.0 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.7 4.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.7 4.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.7 2.7 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.7 11.1 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.6 3.8 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.6 6.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.6 3.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.6 4.4 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.6 6.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.6 1.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.6 4.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.6 1.9 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.6 9.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.6 1.8 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.6 6.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.6 3.6 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.6 7.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.6 9.4 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.6 2.3 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.6 1.7 GO:0072014 proximal tubule development(GO:0072014) negative regulation of androgen receptor activity(GO:2000824)
0.6 1.7 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.6 1.1 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.6 14.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.6 2.3 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.6 10.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.6 2.3 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.6 4.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.6 3.9 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.6 6.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.5 2.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.5 7.5 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.5 2.1 GO:0042335 cuticle development(GO:0042335)
0.5 2.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.5 5.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.5 2.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.5 1.6 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.5 3.1 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.5 3.6 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.5 8.6 GO:0048820 hair follicle maturation(GO:0048820)
0.5 2.0 GO:0021553 olfactory nerve development(GO:0021553)
0.5 20.2 GO:0042417 dopamine metabolic process(GO:0042417)
0.5 7.0 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.5 1.0 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.5 4.4 GO:0006552 leucine catabolic process(GO:0006552)
0.5 2.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5 5.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.5 3.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.5 3.8 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.5 18.1 GO:0006536 glutamate metabolic process(GO:0006536)
0.5 1.9 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.5 14.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.5 4.6 GO:0009414 response to water deprivation(GO:0009414)
0.4 0.4 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.4 2.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.4 4.8 GO:0001842 neural fold formation(GO:0001842)
0.4 1.7 GO:0061304 extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304)
0.4 5.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4 1.2 GO:0035565 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.4 6.0 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.4 3.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.4 1.6 GO:0018094 protein polyglycylation(GO:0018094)
0.4 0.7 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.4 1.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.4 3.6 GO:0016198 axon choice point recognition(GO:0016198)
0.4 5.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 9.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 3.8 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 13.8 GO:0010107 potassium ion import(GO:0010107)
0.3 3.5 GO:0032025 response to cobalt ion(GO:0032025)
0.3 3.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.3 6.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.3 4.0 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3 3.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 3.6 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.3 4.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 1.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.3 2.5 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.3 4.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 9.9 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.3 4.1 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3 0.8 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.3 2.2 GO:0035912 dorsal aorta morphogenesis(GO:0035912)
0.3 3.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 2.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 2.1 GO:0030239 myofibril assembly(GO:0030239)
0.3 11.1 GO:0014047 glutamate secretion(GO:0014047)
0.3 3.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 4.0 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.2 2.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.2 3.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 15.4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.2 1.8 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.2 4.5 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.2 4.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 1.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 1.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.2 1.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 3.2 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.2 0.6 GO:0002159 desmosome assembly(GO:0002159)
0.2 5.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 10.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 4.8 GO:0070207 protein homotrimerization(GO:0070207)
0.2 4.6 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.2 0.9 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 1.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 7.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 2.7 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.2 4.1 GO:2000811 negative regulation of anoikis(GO:2000811)
0.2 3.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 39.3 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 1.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 1.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 3.1 GO:0006972 hyperosmotic response(GO:0006972)
0.2 0.8 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 1.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 9.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 5.1 GO:0016579 protein deubiquitination(GO:0016579)
0.2 3.9 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 1.2 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 3.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 7.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 12.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 3.3 GO:0043691 reverse cholesterol transport(GO:0043691)
0.1 3.1 GO:0050909 sensory perception of taste(GO:0050909)
0.1 3.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 102.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 2.1 GO:0030220 platelet formation(GO:0030220)
0.1 4.3 GO:0007030 Golgi organization(GO:0007030)
0.1 2.5 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.1 1.3 GO:0036315 cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.1 3.2 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.1 1.8 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.1 4.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.9 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 1.8 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 3.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 14.5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 3.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 4.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.6 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 2.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 6.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 4.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 1.0 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 4.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 5.0 GO:1905114 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738) cell surface receptor signaling pathway involved in cell-cell signaling(GO:1905114)
0.1 1.8 GO:0021987 cerebral cortex development(GO:0021987)
0.1 4.3 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 9.1 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.1 2.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 3.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 10.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 9.9 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.1 1.6 GO:0042554 superoxide anion generation(GO:0042554)
0.1 2.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.4 GO:0016050 vesicle organization(GO:0016050)
0.1 0.9 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 2.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.5 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 1.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 2.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 1.5 GO:0097503 sialylation(GO:0097503)
0.1 0.7 GO:0001696 gastric acid secretion(GO:0001696)
0.0 1.5 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 4.5 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 2.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.5 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.7 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.9 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.1 GO:0044266 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.8 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.1 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.9 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 2.4 GO:0001654 eye development(GO:0001654)
0.0 0.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.3 GO:1901998 toxin transport(GO:1901998)
0.0 0.0 GO:0042415 norepinephrine metabolic process(GO:0042415) surfactant homeostasis(GO:0043129)
0.0 0.1 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 28.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
7.0 27.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
3.8 49.9 GO:0097433 dense body(GO:0097433)
3.6 36.0 GO:0097449 astrocyte projection(GO:0097449)
3.5 21.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
3.0 51.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
3.0 41.6 GO:0097227 sperm annulus(GO:0097227)
2.7 13.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
2.6 41.7 GO:0097512 cardiac myofibril(GO:0097512)
2.3 16.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
2.1 36.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
2.0 8.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
2.0 11.8 GO:1990130 Iml1 complex(GO:1990130)
1.7 11.8 GO:0046581 intercellular canaliculus(GO:0046581)
1.7 6.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.6 18.6 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
1.5 10.5 GO:0019815 B cell receptor complex(GO:0019815)
1.4 5.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.4 11.1 GO:0032593 insulin-responsive compartment(GO:0032593)
1.4 5.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
1.3 18.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.2 9.3 GO:0032133 chromosome passenger complex(GO:0032133)
1.1 219.3 GO:0030426 growth cone(GO:0030426)
1.0 7.0 GO:0097452 GAIT complex(GO:0097452)
1.0 44.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.9 2.7 GO:0098536 deuterosome(GO:0098536)
0.9 3.5 GO:0043293 apoptosome(GO:0043293)
0.8 7.5 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.8 5.8 GO:0061617 MICOS complex(GO:0061617)
0.7 4.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.7 2.8 GO:0031085 BLOC-3 complex(GO:0031085)
0.7 3.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 11.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 2.7 GO:0005899 insulin receptor complex(GO:0005899)
0.5 4.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.5 28.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 8.2 GO:0030914 STAGA complex(GO:0030914)
0.5 39.8 GO:0043195 terminal bouton(GO:0043195)
0.5 8.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 4.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 9.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 10.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 22.9 GO:0000786 nucleosome(GO:0000786)
0.4 2.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.4 6.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.4 7.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 3.2 GO:0060077 inhibitory synapse(GO:0060077)
0.3 11.1 GO:0048786 presynaptic active zone(GO:0048786)
0.3 5.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 3.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.9 GO:0032420 stereocilium(GO:0032420)
0.3 0.6 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.3 1.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 5.5 GO:0032590 dendrite membrane(GO:0032590)
0.3 7.5 GO:0034451 centriolar satellite(GO:0034451)
0.3 2.2 GO:0032797 SMN complex(GO:0032797) Gemini of coiled bodies(GO:0097504)
0.3 1.0 GO:0097224 sperm connecting piece(GO:0097224)
0.3 2.5 GO:0036020 endolysosome membrane(GO:0036020)
0.3 2.3 GO:0005579 membrane attack complex(GO:0005579)
0.2 26.8 GO:0016234 inclusion body(GO:0016234)
0.2 3.0 GO:0036038 MKS complex(GO:0036038)
0.2 1.7 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.2 6.6 GO:0002080 acrosomal membrane(GO:0002080)
0.2 6.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 19.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 3.0 GO:0005869 dynactin complex(GO:0005869)
0.2 2.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 0.2 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 3.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 12.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 4.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.2 GO:0033268 node of Ranvier(GO:0033268)
0.2 1.6 GO:0032010 phagolysosome(GO:0032010)
0.2 2.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 39.4 GO:0043209 myelin sheath(GO:0043209)
0.2 24.7 GO:0032587 ruffle membrane(GO:0032587)
0.2 23.3 GO:0005796 Golgi lumen(GO:0005796)
0.2 4.9 GO:0070820 tertiary granule(GO:0070820)
0.1 4.0 GO:0042629 mast cell granule(GO:0042629)
0.1 3.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 5.3 GO:0016592 mediator complex(GO:0016592)
0.1 4.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.5 GO:0005861 troponin complex(GO:0005861)
0.1 2.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 4.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 11.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 4.1 GO:0008305 integrin complex(GO:0008305)
0.1 1.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 5.1 GO:0043679 axon terminus(GO:0043679)
0.1 1.1 GO:0001741 XY body(GO:0001741)
0.1 2.1 GO:0031143 pseudopodium(GO:0031143)
0.1 2.3 GO:0097546 ciliary base(GO:0097546)
0.1 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 14.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.2 GO:0005833 hemoglobin complex(GO:0005833)
0.1 6.8 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 4.3 GO:0005801 cis-Golgi network(GO:0005801)
0.1 6.6 GO:0043204 perikaryon(GO:0043204)
0.1 7.8 GO:0035579 specific granule membrane(GO:0035579)
0.1 5.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 3.7 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 3.0 GO:0045171 intercellular bridge(GO:0045171)
0.1 7.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 96.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 6.1 GO:0005604 basement membrane(GO:0005604)
0.1 2.6 GO:0001533 cornified envelope(GO:0001533)
0.1 3.3 GO:0005657 replication fork(GO:0005657)
0.1 5.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 2.7 GO:0044297 cell body(GO:0044297)
0.0 3.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.9 GO:0032982 myosin filament(GO:0032982)
0.0 2.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0042827 platelet dense granule(GO:0042827)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 59.1 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.7 GO:0005884 actin filament(GO:0005884)
0.0 3.7 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 70.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
5.0 15.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
4.4 22.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
4.4 22.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
4.3 77.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
3.6 14.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
3.6 28.5 GO:0004111 creatine kinase activity(GO:0004111)
3.5 14.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
3.0 11.8 GO:0008431 vitamin E binding(GO:0008431)
2.7 35.6 GO:0046870 cadmium ion binding(GO:0046870)
2.7 13.5 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
2.6 7.9 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.6 36.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
2.5 12.5 GO:0004359 glutaminase activity(GO:0004359)
2.5 76.2 GO:0017075 syntaxin-1 binding(GO:0017075)
2.4 7.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
2.4 11.8 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
2.4 9.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
2.3 29.7 GO:0005344 oxygen transporter activity(GO:0005344)
2.2 13.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.2 6.7 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
2.1 6.4 GO:0019959 interleukin-8 binding(GO:0019959)
1.9 11.3 GO:0008443 phosphofructokinase activity(GO:0008443)
1.8 7.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
1.8 5.3 GO:0019961 interferon binding(GO:0019961)
1.8 21.1 GO:1990459 transferrin receptor binding(GO:1990459)
1.8 24.5 GO:1903136 cuprous ion binding(GO:1903136)
1.7 7.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.7 5.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.6 17.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.5 44.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.4 4.3 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
1.4 41.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.4 11.0 GO:0004064 arylesterase activity(GO:0004064)
1.4 5.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.4 5.5 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
1.3 4.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
1.3 6.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.3 3.8 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
1.2 7.5 GO:0043532 angiostatin binding(GO:0043532)
1.2 9.3 GO:0030172 troponin C binding(GO:0030172)
1.2 5.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.1 6.6 GO:0003796 lysozyme activity(GO:0003796)
1.1 13.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
1.1 33.7 GO:0005212 structural constituent of eye lens(GO:0005212)
1.0 9.3 GO:0035174 histone serine kinase activity(GO:0035174)
1.0 10.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.0 18.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.0 16.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.9 8.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.9 2.7 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.9 2.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.9 2.6 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.9 4.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.8 8.2 GO:0003696 satellite DNA binding(GO:0003696)
0.8 3.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.8 2.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.7 4.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.7 19.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.7 4.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.7 13.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.7 3.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.7 11.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.7 3.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.7 4.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.7 46.2 GO:0043621 protein self-association(GO:0043621)
0.7 7.5 GO:0051525 NFAT protein binding(GO:0051525)
0.7 6.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.7 5.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.7 2.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 3.1 GO:0004771 sterol esterase activity(GO:0004771)
0.6 1.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.6 6.1 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.6 10.3 GO:0031005 filamin binding(GO:0031005)
0.6 3.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.6 4.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.6 2.3 GO:0035473 lipase binding(GO:0035473)
0.6 4.0 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.6 5.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 4.4 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.5 2.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.5 10.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.5 7.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.5 6.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.5 1.6 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.5 1.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.5 5.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.5 3.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.5 15.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 2.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.5 3.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.5 3.0 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.5 3.9 GO:0005497 androgen binding(GO:0005497)
0.5 4.3 GO:0031433 telethonin binding(GO:0031433)
0.5 10.6 GO:0035198 miRNA binding(GO:0035198)
0.5 3.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 1.8 GO:0019862 IgA binding(GO:0019862)
0.4 4.9 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 1.3 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.4 10.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 7.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.4 3.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 3.7 GO:0004985 opioid receptor activity(GO:0004985)
0.4 3.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.4 4.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.4 1.6 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.4 1.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4 10.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.4 1.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 3.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.4 3.6 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.4 5.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 3.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 4.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.3 5.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 2.7 GO:0043559 insulin binding(GO:0043559)
0.3 5.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 15.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 8.4 GO:0016805 dipeptidase activity(GO:0016805)
0.3 5.3 GO:0032052 bile acid binding(GO:0032052)
0.3 1.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 69.7 GO:0000287 magnesium ion binding(GO:0000287)
0.3 8.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 6.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.3 6.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 4.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 9.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 0.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 4.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.3 36.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.3 3.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 4.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 5.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 6.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 23.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 1.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 1.5 GO:0034235 GPI anchor binding(GO:0034235)
0.2 4.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 3.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 3.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 1.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 6.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 1.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 6.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 9.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 4.2 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.2 2.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 2.3 GO:0048185 activin binding(GO:0048185)
0.2 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 3.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 3.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 0.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 2.0 GO:0031432 titin binding(GO:0031432)
0.2 2.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 8.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 2.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 3.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.9 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.9 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 1.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.3 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 3.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 12.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 33.5 GO:0003924 GTPase activity(GO:0003924)
0.1 1.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 3.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 11.1 GO:0005262 calcium channel activity(GO:0005262)
0.1 2.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.7 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 3.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 3.2 GO:0043531 ADP binding(GO:0043531)
0.1 26.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 5.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 1.0 GO:0032027 myosin light chain binding(GO:0032027)
0.1 2.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0099583 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.3 GO:0016499 orexin receptor activity(GO:0016499)
0.1 2.0 GO:0002039 p53 binding(GO:0002039)
0.1 2.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 5.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 3.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 5.4 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.1 2.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 3.3 GO:0005319 lipid transporter activity(GO:0005319)
0.0 10.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 2.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 6.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 5.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0001159 core promoter proximal region DNA binding(GO:0001159)
0.0 5.6 GO:0008017 microtubule binding(GO:0008017)
0.0 1.8 GO:0001047 core promoter binding(GO:0001047)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 6.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 5.8 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.0 1.5 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.6 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 71.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.3 190.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.9 15.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.9 37.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.7 3.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.6 33.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.5 2.7 PID IL5 PATHWAY IL5-mediated signaling events
0.5 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.4 8.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.4 19.0 PID RAS PATHWAY Regulation of Ras family activation
0.4 14.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.4 2.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4 15.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.4 5.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 7.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 5.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.4 12.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 11.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.4 14.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.4 3.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 5.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 3.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.3 9.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.3 1.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 4.5 PID S1P S1P3 PATHWAY S1P3 pathway
0.3 6.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 5.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 13.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 6.7 PID REELIN PATHWAY Reelin signaling pathway
0.2 12.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 10.9 PID ATM PATHWAY ATM pathway
0.2 12.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.2 4.2 PID CONE PATHWAY Visual signal transduction: Cones
0.2 7.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 3.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 6.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 7.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 5.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 11.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 5.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 7.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 4.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 7.1 PID LKB1 PATHWAY LKB1 signaling events
0.2 7.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 5.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.0 PID AP1 PATHWAY AP-1 transcription factor network
0.1 2.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 8.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.2 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 14.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 6.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 44.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.6 27.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.0 12.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.0 20.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.9 11.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.9 13.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.8 10.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.7 11.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.7 8.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.6 29.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.6 31.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.6 13.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.6 15.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 14.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 9.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 16.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 47.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.4 16.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 24.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 15.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 8.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 13.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4 4.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.4 10.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4 7.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 8.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 5.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.3 5.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 10.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.3 5.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3 6.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 9.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 3.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 4.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 3.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 4.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.3 2.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.3 3.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.3 6.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.3 8.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 6.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 6.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 5.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 4.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 3.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 3.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 4.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 32.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 5.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.2 3.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 6.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 11.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 1.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 10.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 34.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 4.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 4.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 3.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 3.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 5.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.4 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 3.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 3.8 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 1.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 4.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 2.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins