averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
NRF1 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000106459.10	nuclear respiratory factor 1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NRF1	hg19_v2_chr7_+_129251531_129251601	-0.37	1.7e-08	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_-_50432782 Show fit	160.64	ENST00000413454.1 ENST00000596437.1 ENST00000341114.3 ENST00000595948.1	NUP62 Links Ensembl NCBI GeneCards UniProt NextProt Show fit IL4I1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 62kDa interleukin 4 induced 1
chr19_+_39138320 Show fit	155.53	ENST00000424234.2 ENST00000390009.3 ENST00000589528.1	ACTN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actinin, alpha 4
chr17_+_40761660 Show fit	147.06	ENST00000251413.3 ENST00000591509.1	TUBG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, gamma 1
chr17_+_7210898 Show fit	144.00	ENST00000572815.1	EIF5A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 5A
chr2_-_33824336 Show fit	133.36	ENST00000431950.1 ENST00000403368.1 ENST00000441530.2	FAM98A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 98, member A
chr8_-_117886955 Show fit	130.81	ENST00000297338.2	RAD21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD21 homolog (S. pombe)
chr5_+_170814803 Show fit	128.67	ENST00000521672.1 ENST00000351986.6 ENST00000393820.2 ENST00000523622.1	NPM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr2_-_33824382 Show fit	115.84	ENST00000238823.8	FAM98A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 98, member A
chr9_+_110045537 Show fit	114.44	ENST00000358015.3	RAD23B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD23 homolog B (S. cerevisiae)
chr3_+_120315149 Show fit	113.47	ENST00000184266.2	NDUFB4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr14_-_23058063 Show fit	109.61	ENST00000538631.1 ENST00000543337.1 ENST00000250498.4	DAD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	defender against cell death 1
chr3_+_120315160 Show fit	108.82	ENST00000485064.1 ENST00000492739.1	NDUFB4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr2_+_216974020 Show fit	106.60	ENST00000392132.2 ENST00000417391.1	XRCC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr20_-_57617831 Show fit	101.95	ENST00000371033.5 ENST00000355937.4	SLMO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	slowmo homolog 2 (Drosophila)
chr5_-_133561752 Show fit	101.74	ENST00000519718.1 ENST00000481195.1	CTD-2410N18.5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit PPP2CA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S-phase kinase-associated protein 1 protein phosphatase 2, catalytic subunit, alpha isozyme
chr19_+_47634039 Show fit	98.31	ENST00000597808.1 ENST00000413379.3 ENST00000600706.1 ENST00000540850.1 ENST00000598840.1 ENST00000600753.1 ENST00000270225.7 ENST00000392776.3	SAE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SUMO1 activating enzyme subunit 1
chr19_-_2328572 Show fit	98.06	ENST00000252622.10	LSM7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_120988229 Show fit	97.50	ENST00000296509.6	MAD2L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MAD2 mitotic arrest deficient-like 1 (yeast)
chr12_+_69080734 Show fit	96.77	ENST00000378905.2	NUP107 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 107kDa
chr1_-_156308018 Show fit	95.34	ENST00000496684.2 ENST00000368259.2 ENST00000368261.3 ENST00000472765.2 ENST00000533194.1 ENST00000478640.2	CCT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 3 (gamma)
chr9_-_124922021 Show fit	95.00	ENST00000537618.1 ENST00000373768.3	NDUFA8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr10_-_58120996 Show fit	92.85	ENST00000361148.6 ENST00000395405.1 ENST00000373944.3	ZWINT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ZW10 interacting kinetochore protein
chr3_+_150321068 Show fit	89.76	ENST00000471696.1 ENST00000477889.1 ENST00000485923.1	SELT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Selenoprotein T
chr2_+_264869 Show fit	88.48	ENST00000272067.6 ENST00000272065.5 ENST00000407983.3	ACP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acid phosphatase 1, soluble
chr16_-_66864806 Show fit	88.28	ENST00000566336.1 ENST00000394074.2 ENST00000563185.2 ENST00000359087.4 ENST00000379463.2 ENST00000565535.1 ENST00000290810.3	NAE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEDD8 activating enzyme E1 subunit 1
chr1_+_154947148 Show fit	87.67	ENST00000368436.1 ENST00000308987.5	CKS1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr19_-_10305752 Show fit	86.01	ENST00000540357.1 ENST00000359526.4 ENST00000340748.4	DNMT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DNA (cytosine-5-)-methyltransferase 1
chr7_-_102213030 Show fit	84.88	ENST00000511313.1 ENST00000513438.1 ENST00000513506.1	POLR2J3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide J3
chr8_+_42249418 Show fit	83.62	ENST00000521158.1 ENST00000022615.4	VDAC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	voltage-dependent anion channel 3
chr1_-_183604794 Show fit	83.19	ENST00000367534.1 ENST00000359856.6 ENST00000294742.6	ARPC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 5, 16kDa
chr8_+_42249346 Show fit	82.66	ENST00000392935.3 ENST00000520115.1 ENST00000522069.1 ENST00000522572.1	VDAC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	voltage-dependent anion channel 3
chr5_+_162887556 Show fit	82.41	ENST00000393915.4 ENST00000432118.2 ENST00000358715.3	HMMR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hyaluronan-mediated motility receptor (RHAMM)
chr1_+_154947126 Show fit	81.86	ENST00000368439.1	CKS1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr3_-_150320937 Show fit	80.54	ENST00000479209.1	SERP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	stress-associated endoplasmic reticulum protein 1
chr2_-_99952769 Show fit	80.33	ENST00000409434.1 ENST00000434323.1 ENST00000264255.3	TXNDC9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin domain containing 9
chr4_-_103789996 Show fit	79.90	ENST00000508238.1	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr20_+_57556263 Show fit	79.45	ENST00000602795.1 ENST00000344018.3	NELFCD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	negative elongation factor complex member C/D
chr17_+_49337881 Show fit	78.99	ENST00000225298.7	UTP18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UTP18 small subunit (SSU) processome component homolog (yeast)
chr21_-_38445470 Show fit	78.48	ENST00000399098.1	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr19_+_17416457 Show fit	78.09	ENST00000252602.1	MRPL34 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L34
chr19_+_49588690 Show fit	77.62	ENST00000221448.5	SNRNP70 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein 70kDa (U1)
chr14_-_102605983 Show fit	76.69	ENST00000334701.7	HSP90AA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr4_+_57301896 Show fit	76.67	ENST00000514888.1 ENST00000264221.2 ENST00000505164.1	PAICS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr19_+_39138271 Show fit	75.99	ENST00000252699.2	ACTN4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actinin, alpha 4
chr19_+_17416609 Show fit	75.73	ENST00000602206.1	MRPL34 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L34
chr21_-_38445011 Show fit	73.92	ENST00000464265.1 ENST00000399102.1	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr10_-_16859361 Show fit	73.35	ENST00000377921.3	RSU1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras suppressor protein 1
chr7_-_102312048 Show fit	72.94	ENST00000333432.6 ENST00000591000.1 ENST00000358438.5	POLR2J2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DNA-directed RNA polymerase II subunit RPB11-b1
chr22_-_28315115 Show fit	71.87	ENST00000455418.3 ENST00000436663.1 ENST00000320996.10 ENST00000335272.5	PITPNB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol transfer protein, beta
chr12_-_54070098 Show fit	71.66	ENST00000394349.3 ENST00000549164.1	ATP5G2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr9_+_91926103 Show fit	71.27	ENST00000314355.6	CKS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CDC28 protein kinase regulatory subunit 2
chr12_-_54069856 Show fit	70.52	ENST00000602871.1	ATP5G2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr11_-_47664072 Show fit	69.82	ENST00000542981.1 ENST00000530428.1 ENST00000302503.3	MTCH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial carrier 2
chr17_-_40761375 Show fit	69.17	ENST00000543197.1 ENST00000309428.5	FAM134C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 134, member C
chr19_+_49588677 Show fit	68.88	ENST00000598984.1 ENST00000598441.1	SNRNP70 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small nuclear ribonucleoprotein 70kDa (U1)
chr5_+_218356 Show fit	68.47	ENST00000264932.6 ENST00000504309.1 ENST00000510361.1	SDHA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr10_+_99185917 Show fit	68.12	ENST00000334828.5	PGAM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoglycerate mutase 1 (brain)
chr1_+_32479430 Show fit	67.55	ENST00000327300.7 ENST00000492989.1	KHDRBS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KH domain containing, RNA binding, signal transduction associated 1
chr4_+_57302297 Show fit	67.10	ENST00000399688.3 ENST00000512576.1	PAICS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr17_+_7210921 Show fit	66.67	ENST00000573542.1	EIF5A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 5A
chr8_-_55014415 Show fit	65.67	ENST00000522007.1 ENST00000521898.1 ENST00000518546.1 ENST00000316963.3	LYPLA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysophospholipase I
chr8_-_55014336 Show fit	65.38	ENST00000343231.6	LYPLA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysophospholipase I
chr21_-_33651324 Show fit	64.68	ENST00000290130.3	MIS18A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MIS18 kinetochore protein A
chr5_+_10250328 Show fit	64.52	ENST00000515390.1	CCT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chaperonin containing TCP1, subunit 5 (epsilon)
chr2_+_190526111 Show fit	64.52	ENST00000607062.1 ENST00000260952.4 ENST00000425590.1 ENST00000607535.1 ENST00000420250.1 ENST00000606910.1 ENST00000607690.1 ENST00000607829.1	ASNSD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	asparagine synthetase domain containing 1
chr10_-_16859442 Show fit	64.06	ENST00000602389.1 ENST00000345264.5	RSU1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras suppressor protein 1
chr17_-_4852332 Show fit	63.85	ENST00000572383.1	PFN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	profilin 1
chr19_-_2427536 Show fit	63.45	ENST00000591871.1	TIMM13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr6_-_36515177 Show fit	63.32	ENST00000229812.7	STK38 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/threonine kinase 38
chr6_-_41040195 Show fit	62.57	ENST00000463088.1 ENST00000469104.1 ENST00000486443.1	OARD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	O-acyl-ADP-ribose deacylase 1
chr12_+_57623869 Show fit	62.43	ENST00000414700.3 ENST00000557703.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_11071685 Show fit	61.93	ENST00000541122.2 ENST00000589677.1 ENST00000444061.3	SMARCA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr21_-_38445443 Show fit	61.31	ENST00000360525.4	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr3_-_119396193 Show fit	61.30	ENST00000484810.1 ENST00000497116.1 ENST00000261070.2	COX17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	COX17 cytochrome c oxidase copper chaperone
chr13_+_50656307 Show fit	61.23	ENST00000378180.4	DLEU1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	deleted in lymphocytic leukemia 1 (non-protein coding)
chrX_-_129299847 Show fit	61.07	ENST00000319908.3 ENST00000287295.3	AIFM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apoptosis-inducing factor, mitochondrion-associated, 1
chr4_+_17616253 Show fit	60.87	ENST00000237380.7	MED28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 28
chrX_-_153707246 Show fit	60.02	ENST00000407062.1	LAGE3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	L antigen family, member 3
chr19_+_8509842 Show fit	59.87	ENST00000325495.4 ENST00000600092.1 ENST00000594907.1 ENST00000596984.1 ENST00000601645.1	HNRNPM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein M
chr21_-_38445297 Show fit	59.86	ENST00000430792.1 ENST00000399103.1	PIGP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr4_+_57845043 Show fit	59.51	ENST00000433463.1 ENST00000314595.5	POLR2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chrX_-_129299638 Show fit	59.42	ENST00000535724.1 ENST00000346424.2	AIFM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apoptosis-inducing factor, mitochondrion-associated, 1
chr4_+_57845024 Show fit	58.33	ENST00000431623.2 ENST00000441246.2	POLR2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr19_+_531713 Show fit	58.03	ENST00000215574.4	CDC34 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 34
chr18_+_12947981 Show fit	58.00	ENST00000262124.11	SEH1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEH1-like (S. cerevisiae)
chr18_-_54305658 Show fit	57.56	ENST00000586262.1 ENST00000217515.6	TXNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin-like 1
chr3_-_48647470 Show fit	57.40	ENST00000203407.5	UQCRC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquinol-cytochrome c reductase core protein I
chr10_-_71993176 Show fit	57.34	ENST00000373232.3	PPA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pyrophosphatase (inorganic) 1
chr8_-_109260897 Show fit	57.09	ENST00000521297.1 ENST00000519030.1 ENST00000521440.1 ENST00000518345.1 ENST00000519627.1 ENST00000220849.5	EIF3E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3, subunit E
chr6_-_31774714 Show fit	56.76	ENST00000375661.5	LSM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr9_+_117350009 Show fit	56.68	ENST00000374050.3	ATP6V1G1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr11_+_108535752 Show fit	56.59	ENST00000322536.3	DDX10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr7_-_102119342 Show fit	56.34	ENST00000393794.3 ENST00000292614.5	POLR2J Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr11_+_18417813 Show fit	56.12	ENST00000540430.1 ENST00000379412.5	LDHA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lactate dehydrogenase A
chr17_-_47492164 Show fit	56.08	ENST00000512041.2 ENST00000446735.1 ENST00000504124.1	PHB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prohibitin
chr1_+_41445413 Show fit	56.00	ENST00000541520.1	CTPS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CTP synthase 1
chr19_-_40336969 Show fit	55.85	ENST00000599134.1 ENST00000597634.1 ENST00000598417.1 ENST00000601274.1 ENST00000594309.1 ENST00000221801.3	FBL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrillarin
chr1_-_246670519 Show fit	55.77	ENST00000388985.4 ENST00000490107.1	SMYD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SET and MYND domain containing 3
chr1_-_8939265 Show fit	55.34	ENST00000489867.1	ENO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 1, (alpha)
chr22_+_32340481 Show fit	55.29	ENST00000397492.1	YWHAH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr6_-_35888905 Show fit	55.18	ENST00000510290.1 ENST00000423325.2 ENST00000373822.1	SRPK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SRSF protein kinase 1
chr22_+_32340447 Show fit	54.88	ENST00000248975.5	YWHAH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr12_+_48357340 Show fit	54.64	ENST00000256686.6 ENST00000549288.1 ENST00000552561.1 ENST00000546749.1 ENST00000552546.1 ENST00000550552.1	TMEM106C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 106C
chr12_+_109535373 Show fit	53.88	ENST00000242576.2	UNG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	uracil-DNA glycosylase
chr20_-_5107180 Show fit	53.68	ENST00000379160.3	PCNA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proliferating cell nuclear antigen
chrX_-_16888448 Show fit	53.67	ENST00000468092.1 ENST00000404022.1 ENST00000380087.2	RBBP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoblastoma binding protein 7
chr4_-_103790026 Show fit	53.64	ENST00000338145.3 ENST00000357194.6	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr21_-_46293586 Show fit	52.80	ENST00000445724.2 ENST00000397887.3	PTTG1IP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pituitary tumor-transforming 1 interacting protein
chr19_+_36630855 Show fit	52.65	ENST00000589146.1	CAPNS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calpain, small subunit 1
chr20_-_48729670 Show fit	52.64	ENST00000371657.5	UBE2V1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2 variant 1
chr12_+_48357401 Show fit	52.37	ENST00000429772.2 ENST00000449758.2	TMEM106C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 106C
chr17_+_3572087 Show fit	52.19	ENST00000248378.5 ENST00000397133.2	EMC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ER membrane protein complex subunit 6
chr11_-_6704513 Show fit	52.19	ENST00000532203.1 ENST00000288937.6	MRPL17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L17
chr12_+_57623477 Show fit	51.97	ENST00000557487.1 ENST00000555634.1 ENST00000556689.1	SHMT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_572543 Show fit	51.67	ENST00000333511.3 ENST00000573216.1 ENST00000353555.4	BSG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	basigin (Ok blood group)
chr21_-_46293644 Show fit	51.63	ENST00000330938.3	PTTG1IP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pituitary tumor-transforming 1 interacting protein
chr19_+_59055814 Show fit	51.32	ENST00000594806.1 ENST00000253024.5 ENST00000341753.6	TRIM28 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 28
chr19_-_1095330 Show fit	50.83	ENST00000586746.1	POLR2E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr19_+_11071546 Show fit	50.67	ENST00000358026.2	SMARCA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr20_+_62887081 Show fit	50.08	ENST00000369758.4 ENST00000299468.7 ENST00000609372.1 ENST00000610196.1 ENST00000308824.6	PCMTD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr14_-_102553371 Show fit	50.07	ENST00000553585.1 ENST00000216281.8	HSP90AA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr17_-_4852243 Show fit	50.05	ENST00000225655.5	PFN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	profilin 1
chr15_+_78833071 Show fit	50.03	ENST00000559365.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr6_+_24775153 Show fit	49.89	ENST00000356509.3 ENST00000230056.3	GMNN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	geminin, DNA replication inhibitor
chr10_-_74856608 Show fit	49.86	ENST00000307116.2 ENST00000373008.2 ENST00000412021.2 ENST00000394890.2 ENST00000263556.3 ENST00000440381.1	P4HA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl 4-hydroxylase, alpha polypeptide I
chr11_+_60681346 Show fit	49.82	ENST00000227525.3	TMEM109 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 109
chr19_+_11071652 Show fit	49.71	ENST00000344626.4 ENST00000429416.3	SMARCA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr13_+_76123883 Show fit	49.67	ENST00000377595.3	UCHL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr12_+_108079664 Show fit	49.25	ENST00000541166.1	PWP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PWP1 homolog (S. cerevisiae)
chr10_+_60028818 Show fit	49.25	ENST00000333926.5	CISD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CDGSH iron sulfur domain 1
chr16_-_88878305 Show fit	48.94	ENST00000569616.1 ENST00000563655.1 ENST00000567713.1 ENST00000426324.2 ENST00000378364.3	APRT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenine phosphoribosyltransferase
chr5_-_96518907 Show fit	48.84	ENST00000508447.1 ENST00000283109.3	RIOK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RIO kinase 2
chr6_+_52535878 Show fit	48.70	ENST00000211314.4	TMEM14A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 14A
chr15_+_79603404 Show fit	48.70	ENST00000299705.5	TMED3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane emp24 protein transport domain containing 3
chr6_+_24667257 Show fit	48.70	ENST00000537591.1 ENST00000230048.4	ACOT13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acyl-CoA thioesterase 13
chrX_+_70503037 Show fit	48.63	ENST00000535149.1	NONO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	non-POU domain containing, octamer-binding
chr11_-_77850629 Show fit	48.61	ENST00000376156.3 ENST00000525870.1 ENST00000530454.1 ENST00000525755.1 ENST00000527099.1 ENST00000525761.1 ENST00000299626.5	ALG8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ALG8, alpha-1,3-glucosyltransferase
chr11_+_114310102 Show fit	48.31	ENST00000265881.5	REXO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA exonuclease 2
chr7_+_116502605 Show fit	47.51	ENST00000458284.2 ENST00000490693.1	CAPZA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	capping protein (actin filament) muscle Z-line, alpha 2
chr12_-_31479045 Show fit	47.40	ENST00000539409.1 ENST00000395766.1	FAM60A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 60, member A
chr2_+_86333301 Show fit	47.34	ENST00000254630.7	PTCD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pentatricopeptide repeat domain 3
chr10_-_88281494 Show fit	47.28	ENST00000298767.5	WAPAL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	wings apart-like homolog (Drosophila)
chr20_+_39657454 Show fit	47.08	ENST00000361337.2	TOP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	topoisomerase (DNA) I
chr8_+_145137489 Show fit	47.05	ENST00000355091.4 ENST00000525087.1 ENST00000361036.6 ENST00000524418.1	GPAA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glycosylphosphatidylinositol anchor attachment 1
chr18_-_12884259 Show fit	46.99	ENST00000353319.4 ENST00000327283.3	PTPN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, non-receptor type 2
chr1_+_16174280 Show fit	46.97	ENST00000375759.3	SPEN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spen family transcriptional repressor
chr20_+_61427797 Show fit	46.93	ENST00000370487.3	MRGBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MRG/MORF4L binding protein
chr5_+_68462837 Show fit	46.71	ENST00000256442.5	CCNB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin B1
chr2_-_106810783 Show fit	46.23	ENST00000283148.7	UXS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-glucuronate decarboxylase 1
chr2_-_86790593 Show fit	45.92	ENST00000263856.4 ENST00000409225.2	CHMP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	charged multivesicular body protein 3
chr20_+_35234137 Show fit	45.88	ENST00000344795.3 ENST00000373852.5	C20orf24 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 20 open reading frame 24
chr15_+_78833105 Show fit	45.60	ENST00000558341.1 ENST00000559437.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr11_+_114310164 Show fit	45.47	ENST00000544196.1 ENST00000539754.1 ENST00000539275.1	REXO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA exonuclease 2
chr3_+_160117087 Show fit	45.43	ENST00000357388.3	SMC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 4
chr11_-_76091986 Show fit	45.23	ENST00000260045.3	PRKRIR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr2_-_150444300 Show fit	44.83	ENST00000303319.5	MMADHC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr19_+_984313 Show fit	44.79	ENST00000251289.5 ENST00000587001.2 ENST00000607440.1	WDR18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 18
chr1_+_212208919 Show fit	44.66	ENST00000366991.4 ENST00000542077.1	DTL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr5_+_154320623 Show fit	44.62	ENST00000523037.1 ENST00000265229.8 ENST00000439747.3 ENST00000522038.1	MRPL22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein L22
chr20_+_55926274 Show fit	44.50	ENST00000371242.2 ENST00000527947.1	RAE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonucleic acid export 1
chr10_-_103578182 Show fit	44.31	ENST00000439817.1	MGEA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	meningioma expressed antigen 5 (hyaluronidase)
chr19_-_55770311 Show fit	44.05	ENST00000412770.2	PPP6R1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 6, regulatory subunit 1
chr6_-_24667232 Show fit	44.04	ENST00000378198.4	TDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosyl-DNA phosphodiesterase 2
chr1_+_91966384 Show fit	44.04	ENST00000430031.2 ENST00000234626.6	CDC7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 7
chr2_-_38978492 Show fit	43.87	ENST00000409276.1 ENST00000446327.2 ENST00000313117.6	SRSF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine-rich splicing factor 7
chr6_+_32936353 Show fit	43.72	ENST00000374825.4	BRD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	bromodomain containing 2
chr6_+_24403144 Show fit	43.63	ENST00000274747.7 ENST00000543597.1 ENST00000535061.1 ENST00000378353.1 ENST00000378386.3 ENST00000443868.2	MRS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MRS2 magnesium transporter
chr11_+_114310237 Show fit	43.62	ENST00000539119.1	REXO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA exonuclease 2
chr7_+_116502527 Show fit	43.59	ENST00000361183.3	CAPZA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	capping protein (actin filament) muscle Z-line, alpha 2
chr20_+_35234223 Show fit	43.53	ENST00000342422.3	C20orf24 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 20 open reading frame 24
chr6_-_35888824 Show fit	43.44	ENST00000361690.3 ENST00000512445.1	SRPK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SRSF protein kinase 1
chr19_-_36606181 Show fit	43.36	ENST00000221859.4	POLR2I Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr15_+_78832747 Show fit	43.22	ENST00000560217.1 ENST00000044462.7 ENST00000559082.1 ENST00000559948.1 ENST00000413382.2 ENST00000559146.1 ENST00000558281.1	PSMA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 4
chr1_+_91966656 Show fit	43.20	ENST00000428239.1 ENST00000426137.1	CDC7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cell division cycle 7
chr20_-_32700075 Show fit	43.10	ENST00000374980.2	EIF2S2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr16_-_75681522 Show fit	43.01	ENST00000568378.1 ENST00000568682.1 ENST00000570215.1 ENST00000319410.5 ENST00000302445.3	KARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysyl-tRNA synthetase
chr5_+_33441053 Show fit	42.94	ENST00000541634.1 ENST00000455217.2 ENST00000414361.2	TARS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	threonyl-tRNA synthetase
chr3_+_37035263 Show fit	42.65	ENST00000458205.2 ENST00000539477.1	MLH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mutL homolog 1
chr19_-_59066327 Show fit	42.51	ENST00000596708.1 ENST00000601220.1 ENST00000597848.1	CHMP2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	charged multivesicular body protein 2A
chr1_-_19536744 Show fit	42.39	ENST00000375267.2 ENST00000375217.2 ENST00000375226.2 ENST00000375254.3	UBR4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin protein ligase E3 component n-recognin 4
chrX_+_51636629 Show fit	42.28	ENST00000375722.1 ENST00000326587.7 ENST00000375695.2	MAGED1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	melanoma antigen family D, 1
chr6_-_24667180 Show fit	42.23	ENST00000545995.1	TDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosyl-DNA phosphodiesterase 2
chr5_+_68462944 Show fit	42.03	ENST00000506572.1	CCNB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin B1
chr10_+_62538089 Show fit	41.95	ENST00000519078.2 ENST00000395284.3 ENST00000316629.4	CDK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 1
chr1_+_100731749 Show fit	41.89	ENST00000370128.4 ENST00000260563.4	RTCA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA 3'-terminal phosphate cyclase
chr14_+_75230011 Show fit	41.89	ENST00000552421.1 ENST00000325680.7 ENST00000238571.3	YLPM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	YLP motif containing 1
chr3_+_52232102 Show fit	41.85	ENST00000469224.1 ENST00000394965.2 ENST00000310271.2 ENST00000484952.1	ALAS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aminolevulinate, delta-, synthase 1
chr18_+_12948000 Show fit	41.82	ENST00000585730.1 ENST00000399892.2 ENST00000589446.1 ENST00000587761.1	SEH1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEH1-like (S. cerevisiae)
chr4_+_39699664 Show fit	41.74	ENST00000261427.5 ENST00000510934.1 ENST00000295963.6	UBE2K Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2K
chr20_+_11871371 Show fit	41.74	ENST00000254977.3	BTBD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BTB (POZ) domain containing 3
chr3_-_107809816 Show fit	41.65	ENST00000361309.5 ENST00000355354.7	CD47 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD47 molecule
chr17_+_73201754 Show fit	41.64	ENST00000583569.1 ENST00000245544.4 ENST00000579324.1 ENST00000541827.1 ENST00000579298.1 ENST00000447371.2	NUP85 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 85kDa
chr19_-_14530143 Show fit	41.51	ENST00000242776.4	DDX39A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr3_+_160117418 Show fit	41.50	ENST00000465903.1 ENST00000485645.1 ENST00000360111.2 ENST00000472991.1 ENST00000467468.1 ENST00000469762.1 ENST00000489573.1 ENST00000462787.1 ENST00000490207.1 ENST00000485867.1	SMC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 4
chr1_-_109968973 Show fit	41.41	ENST00000271308.4 ENST00000538610.1	PSMA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 5
chr14_-_104387888 Show fit	41.29	ENST00000286953.3	C14orf2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 2
chr20_+_55926583 Show fit	41.25	ENST00000395840.2	RAE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonucleic acid export 1
chr6_-_41040268 Show fit	40.91	ENST00000373154.2 ENST00000244558.9 ENST00000464633.1 ENST00000424266.2 ENST00000479950.1 ENST00000482515.1	OARD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	O-acyl-ADP-ribose deacylase 1
chr17_-_46178527 Show fit	40.78	ENST00000393408.3	CBX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 1
chr10_-_103578162 Show fit	40.63	ENST00000361464.3 ENST00000357797.5 ENST00000370094.3	MGEA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	meningioma expressed antigen 5 (hyaluronidase)

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
77.2	231.5	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
44.1	176.5	GO:1903490	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
42.7	128.2	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
38.8	193.9	GO:0007068	negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
36.2	144.6	GO:0043335	protein unfolding(GO:0043335)
35.5	106.6	GO:1904430	negative regulation of t-circle formation(GO:1904430)
33.4	100.2	GO:0045950	meiotic metaphase I plate congression(GO:0043060) negative regulation of mitotic recombination(GO:0045950) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
31.0	154.8	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
30.9	92.7	GO:1903722	regulation of centriole elongation(GO:1903722)
29.7	207.7	GO:1903333	negative regulation of protein folding(GO:1903333)
29.5	88.4	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
29.3	176.0	GO:0015853	adenine transport(GO:0015853)
28.4	227.0	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
28.2	84.5	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
28.2	112.6	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
26.7	80.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
26.3	131.3	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
24.9	74.8	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
24.2	145.2	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
24.0	72.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
22.4	67.2	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
22.0	88.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
22.0	87.9	GO:0070370	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
21.8	65.3	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
21.5	64.6	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
21.2	63.5	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
20.4	265.3	GO:1904871	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
19.4	96.8	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
19.1	57.3	GO:0071344	diphosphate metabolic process(GO:0071344)
19.0	57.0	GO:0002188	translation reinitiation(GO:0002188)
18.9	18.9	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
18.7	56.0	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
18.6	241.2	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
18.4	55.3	GO:1903298	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
18.1	144.7	GO:0060699	regulation of endoribonuclease activity(GO:0060699)
18.1	54.2	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
17.8	35.7	GO:0046098	guanine metabolic process(GO:0046098)
17.7	88.3	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
17.5	52.6	GO:1902661	positive regulation of glucose mediated signaling pathway(GO:1902661)
17.2	120.5	GO:1904044	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
17.0	68.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
16.9	67.6	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
16.3	114.4	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
16.3	146.5	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
16.1	80.4	GO:1902410	mitotic cytokinetic process(GO:1902410)
15.7	31.4	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
15.3	92.0	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
14.8	44.5	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
14.7	117.4	GO:0002176	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
14.6	87.6	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
14.5	87.2	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
14.4	43.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
14.2	85.4	GO:0071035	nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
14.1	42.3	GO:0031126	snoRNA 3'-end processing(GO:0031126)
14.0	14.0	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
13.9	55.7	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
13.8	41.3	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
13.7	137.2	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
13.6	81.5	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
13.5	53.9	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
13.4	26.8	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
13.4	40.1	GO:0060380	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
13.3	266.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
13.3	26.6	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
13.2	105.6	GO:0010032	meiotic chromosome condensation(GO:0010032)
13.2	39.5	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
13.2	13.2	GO:0030047	actin modification(GO:0030047)
13.1	39.4	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
13.1	52.5	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
13.1	39.3	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
13.1	39.2	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
12.9	38.8	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
12.9	38.7	GO:1903970	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
12.9	64.5	GO:0006529	asparagine biosynthetic process(GO:0006529)
12.9	77.2	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
12.8	12.8	GO:1902822	regulation of late endosome to lysosome transport(GO:1902822)
12.3	160.4	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
12.3	61.5	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
12.2	85.7	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
12.2	36.5	GO:0002276	basophil activation involved in immune response(GO:0002276)
12.0	47.8	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
11.9	35.6	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
11.8	35.3	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
11.7	668.5	GO:0050434	positive regulation of viral transcription(GO:0050434)
11.5	114.8	GO:0035092	sperm chromatin condensation(GO:0035092)
11.4	113.9	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
11.4	56.9	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
11.3	22.6	GO:0061739	protein lipidation involved in autophagosome assembly(GO:0061739)
11.1	133.4	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
11.1	77.8	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
11.1	66.4	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
10.9	349.7	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
10.8	32.5	GO:0036509	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
10.7	74.9	GO:1902416	positive regulation of mRNA binding(GO:1902416)
10.6	31.9	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
10.6	31.8	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
10.6	74.1	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
10.6	31.7	GO:0036071	N-glycan fucosylation(GO:0036071)
10.3	41.2	GO:0046502	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
10.3	133.7	GO:0000212	meiotic spindle organization(GO:0000212)
10.2	82.0	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
10.2	173.9	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
10.1	302.7	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
10.1	30.2	GO:1990922	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
10.0	30.1	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
10.0	30.0	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
9.9	98.9	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
9.8	48.9	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
9.7	19.4	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
9.7	58.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
9.7	38.8	GO:0016259	selenocysteine metabolic process(GO:0016259) negative regulation of vascular endothelial growth factor production(GO:1904046)
9.6	57.7	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
9.6	96.2	GO:0071578	zinc II ion transmembrane import(GO:0071578)
9.6	95.9	GO:0051096	positive regulation of helicase activity(GO:0051096)
9.4	28.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
9.4	9.4	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
9.3	18.5	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
9.2	27.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
9.1	27.4	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
9.1	36.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
9.1	45.4	GO:0042780	tRNA 3'-end processing(GO:0042780)
9.0	63.3	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
8.9	35.6	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
8.9	70.9	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
8.8	35.3	GO:0016333	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
8.5	34.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
8.5	42.4	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
8.4	42.2	GO:0061198	fungiform papilla formation(GO:0061198)
8.3	83.2	GO:0021769	orbitofrontal cortex development(GO:0021769)
8.3	49.7	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
8.3	8.3	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
8.3	157.1	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
8.2	16.4	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512)
8.1	24.3	GO:0072554	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
8.1	518.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
8.1	16.2	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
8.1	24.2	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
8.0	56.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
8.0	95.9	GO:0006089	lactate metabolic process(GO:0006089)
7.8	38.9	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
7.7	84.9	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
7.7	123.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
7.7	38.4	GO:0090646	mitochondrial tRNA processing(GO:0090646)
7.7	161.3	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
7.7	23.0	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
7.7	30.7	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
7.5	15.0	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
7.4	29.5	GO:1903719	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
7.2	101.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
7.1	42.6	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
7.0	13.9	GO:0035617	stress granule disassembly(GO:0035617)
6.9	34.6	GO:0009181	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
6.8	47.7	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
6.8	47.6	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
6.7	66.9	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
6.4	32.0	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
6.4	31.9	GO:0051661	maintenance of centrosome location(GO:0051661)
6.3	37.9	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
6.3	25.2	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
6.3	18.8	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
6.3	68.8	GO:0031584	activation of phospholipase D activity(GO:0031584)
6.2	112.4	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
6.2	18.6	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
6.1	18.2	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
6.0	42.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
6.0	23.9	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
6.0	29.8	GO:2000782	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
5.9	5.9	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
5.9	41.4	GO:0022417	protein maturation by protein folding(GO:0022417)
5.9	23.6	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
5.9	35.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
5.8	29.2	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
5.8	241.8	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
5.7	136.4	GO:0032008	positive regulation of TOR signaling(GO:0032008)
5.6	22.5	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
5.6	72.8	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
5.5	83.1	GO:0090168	Golgi reassembly(GO:0090168)
5.5	38.8	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
5.5	22.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
5.5	27.4	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
5.5	11.0	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
5.5	21.9	GO:1901895	positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
5.4	21.8	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
5.4	27.2	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
5.4	10.8	GO:0097327	response to antineoplastic agent(GO:0097327)
5.4	27.0	GO:1902904	vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
5.4	145.9	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
5.4	53.9	GO:0045008	depyrimidination(GO:0045008)
5.3	26.7	GO:1902896	terminal web assembly(GO:1902896)
5.3	16.0	GO:0085032	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
5.3	63.4	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
5.2	31.4	GO:2000773	negative regulation of cellular senescence(GO:2000773)
5.1	20.6	GO:0071373	cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
5.1	30.7	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
5.1	25.6	GO:0016926	protein desumoylation(GO:0016926)
5.1	35.8	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
5.1	121.5	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
5.1	177.0	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
5.0	5.0	GO:0048372	lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
5.0	25.1	GO:0032790	ribosome disassembly(GO:0032790)
5.0	40.1	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
5.0	40.0	GO:0015846	polyamine transport(GO:0015846)
5.0	24.9	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
5.0	29.9	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
5.0	10.0	GO:0072321	chaperone-mediated protein transport(GO:0072321)
5.0	29.8	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
4.9	14.8	GO:0002553	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
4.9	63.9	GO:0001682	tRNA 5'-leader removal(GO:0001682)
4.9	363.0	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
4.9	39.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
4.9	24.5	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
4.9	19.4	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
4.8	52.7	GO:0045116	protein neddylation(GO:0045116)
4.8	23.8	GO:0060356	leucine import(GO:0060356)
4.7	132.6	GO:0043968	histone H2A acetylation(GO:0043968)
4.7	23.6	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
4.6	111.3	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
4.6	13.9	GO:0045896	regulation of transcription during mitosis(GO:0045896)
4.6	509.1	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
4.5	49.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
4.5	75.9	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
4.4	8.9	GO:0000012	single strand break repair(GO:0000012)
4.4	44.1	GO:0046689	response to mercury ion(GO:0046689)
4.4	8.8	GO:0042256	mature ribosome assembly(GO:0042256)
4.4	148.7	GO:0090383	phagosome acidification(GO:0090383)
4.3	30.3	GO:0070294	renal sodium ion absorption(GO:0070294)
4.3	12.9	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
4.3	12.9	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
4.3	17.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
4.2	50.6	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
4.2	41.8	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
4.2	108.7	GO:0006825	copper ion transport(GO:0006825)
4.2	54.2	GO:0040016	embryonic cleavage(GO:0040016)
4.2	12.5	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
4.1	12.4	GO:0003383	apical constriction(GO:0003383)
4.1	4.1	GO:1905216	positive regulation of RNA binding(GO:1905216)
4.1	49.2	GO:0043457	regulation of cellular respiration(GO:0043457)
4.0	52.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
3.9	15.7	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
3.9	27.4	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
3.9	346.8	GO:0090114	COPII-coated vesicle budding(GO:0090114)
3.9	81.8	GO:0033120	positive regulation of RNA splicing(GO:0033120)
3.9	19.4	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
3.8	11.4	GO:1904386	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
3.8	67.6	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
3.7	82.4	GO:0030214	hyaluronan catabolic process(GO:0030214)
3.7	22.0	GO:0035562	negative regulation of chromatin binding(GO:0035562)
3.6	91.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
3.6	43.4	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
3.6	90.2	GO:0009235	cobalamin metabolic process(GO:0009235)
3.6	10.8	GO:2000395	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
3.5	24.8	GO:0042407	cristae formation(GO:0042407)
3.5	14.1	GO:0072719	cellular response to cisplatin(GO:0072719)
3.5	7.0	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
3.5	10.5	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
3.4	6.8	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
3.4	10.3	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
3.4	85.2	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
3.4	43.9	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
3.4	46.9	GO:0040008	regulation of growth(GO:0040008)
3.3	30.0	GO:0030091	protein repair(GO:0030091)
3.3	29.7	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
3.3	6.6	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
3.3	22.9	GO:0031017	exocrine pancreas development(GO:0031017)
3.3	9.8	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
3.2	130.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
3.2	85.8	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
3.2	82.0	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
3.1	18.9	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
3.1	71.3	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
3.1	24.8	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
3.1	12.3	GO:0080009	mRNA methylation(GO:0080009)
3.0	154.4	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
3.0	101.7	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
3.0	12.0	GO:0098789	mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
3.0	23.8	GO:0035518	histone H2A monoubiquitination(GO:0035518)
2.9	2.9	GO:0090385	phagosome-lysosome fusion(GO:0090385)
2.9	5.8	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
2.9	14.5	GO:1904896	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
2.9	49.0	GO:0035855	megakaryocyte development(GO:0035855)
2.9	28.8	GO:0009414	response to water deprivation(GO:0009414)
2.9	25.9	GO:0035458	cellular response to interferon-beta(GO:0035458)
2.9	23.0	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
2.8	34.1	GO:0031063	regulation of histone deacetylation(GO:0031063)
2.8	22.5	GO:0030263	apoptotic chromosome condensation(GO:0030263)
2.8	25.2	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
2.8	72.6	GO:0006270	DNA replication initiation(GO:0006270)
2.8	22.2	GO:0000470	maturation of LSU-rRNA(GO:0000470)
2.8	8.3	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
2.7	30.2	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
2.7	8.2	GO:1901143	insulin catabolic process(GO:1901143)
2.7	27.1	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
2.7	13.5	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
2.7	29.5	GO:0006105	succinate metabolic process(GO:0006105)
2.7	10.7	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
2.6	7.9	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
2.6	10.5	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
2.6	23.6	GO:0018344	protein geranylgeranylation(GO:0018344)
2.6	41.7	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
2.6	10.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
2.6	10.3	GO:0035720	intraciliary anterograde transport(GO:0035720)
2.5	15.2	GO:2000568	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.5	27.7	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
2.5	32.3	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
2.4	7.3	GO:0071109	superior temporal gyrus development(GO:0071109)
2.4	9.8	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
2.4	14.4	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
2.4	14.4	GO:0006499	N-terminal protein myristoylation(GO:0006499)
2.4	7.2	GO:1904526	regulation of microtubule binding(GO:1904526)
2.4	11.9	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
2.4	23.7	GO:0051382	kinetochore assembly(GO:0051382)
2.4	16.6	GO:0000160	phosphorelay signal transduction system(GO:0000160)
2.4	4.7	GO:0036034	mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
2.3	27.8	GO:0035067	negative regulation of histone acetylation(GO:0035067)
2.3	20.8	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
2.3	6.9	GO:0060295	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
2.3	20.7	GO:0042373	vitamin K metabolic process(GO:0042373)
2.3	20.5	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
2.3	25.0	GO:2000582	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
2.2	98.7	GO:0006414	translational elongation(GO:0006414)
2.2	15.6	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
2.2	17.7	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
2.2	81.7	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
2.2	6.6	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
2.2	15.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
2.2	19.8	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
2.2	41.7	GO:0008228	opsonization(GO:0008228)
2.2	6.6	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
2.2	15.3	GO:0000722	telomere maintenance via recombination(GO:0000722)
2.1	36.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.1	8.5	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
2.1	12.6	GO:1903800	regulation of Golgi inheritance(GO:0090170) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
2.1	16.7	GO:0015693	magnesium ion transport(GO:0015693)
2.1	24.9	GO:0006379	mRNA cleavage(GO:0006379)
2.1	12.4	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
2.0	14.3	GO:0071763	nuclear membrane organization(GO:0071763)
2.0	236.6	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
2.0	170.2	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
2.0	32.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
2.0	4.0	GO:0061511	centriole elongation(GO:0061511)
2.0	9.9	GO:0035372	protein localization to microtubule(GO:0035372)
2.0	7.9	GO:0051683	establishment of Golgi localization(GO:0051683)
2.0	7.9	GO:0008063	Toll signaling pathway(GO:0008063)
2.0	15.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
2.0	35.4	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.9	17.4	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.9	5.7	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.9	11.5	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.9	26.6	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
1.9	7.6	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.9	17.0	GO:0038007	netrin-activated signaling pathway(GO:0038007)
1.9	80.5	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
1.9	63.4	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
1.8	14.8	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
1.8	14.6	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
1.8	7.2	GO:0000103	sulfate assimilation(GO:0000103)
1.8	35.7	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
1.8	7.0	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
1.8	7.0	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.7	22.7	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
1.7	10.5	GO:0006537	glutamate biosynthetic process(GO:0006537)
1.7	10.4	GO:0051694	pointed-end actin filament capping(GO:0051694)
1.7	34.3	GO:0051290	protein heterotetramerization(GO:0051290)
1.7	43.6	GO:0045948	positive regulation of translational initiation(GO:0045948)
1.7	16.7	GO:2000772	regulation of cellular senescence(GO:2000772)
1.7	6.7	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.7	24.9	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
1.7	16.6	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.6	54.3	GO:0048246	macrophage chemotaxis(GO:0048246)
1.6	11.2	GO:0090382	phagosome maturation(GO:0090382)
1.6	42.3	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.5	71.9	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
1.5	3.0	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.5	25.7	GO:0006378	mRNA polyadenylation(GO:0006378)
1.5	24.0	GO:0097284	hepatocyte apoptotic process(GO:0097284)
1.5	10.5	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.4	18.7	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
1.4	15.8	GO:0006924	activation-induced cell death of T cells(GO:0006924)
1.4	8.5	GO:0007296	vitellogenesis(GO:0007296)
1.4	9.9	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
1.4	59.8	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
1.3	4.0	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.3	12.9	GO:0043651	linoleic acid metabolic process(GO:0043651)
1.3	11.6	GO:0046477	glycosylceramide catabolic process(GO:0046477)
1.3	11.5	GO:0030705	cytoskeleton-dependent intracellular transport(GO:0030705)
1.3	13.9	GO:0043086	negative regulation of catalytic activity(GO:0043086)
1.3	35.3	GO:0050435	beta-amyloid metabolic process(GO:0050435)
1.3	15.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.2	18.6	GO:0006750	glutathione biosynthetic process(GO:0006750)
1.2	48.2	GO:2000142	regulation of DNA-templated transcription, initiation(GO:2000142)
1.2	7.4	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
1.2	6.0	GO:1990834	response to odorant(GO:1990834)
1.2	7.2	GO:0010506	regulation of autophagy(GO:0010506)
1.2	1.2	GO:0031929	TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
1.2	36.6	GO:0007019	microtubule depolymerization(GO:0007019)
1.2	88.6	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.2	15.1	GO:0042113	B cell activation(GO:0042113)
1.1	13.8	GO:0070327	thyroid hormone transport(GO:0070327)
1.1	3.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
1.1	75.6	GO:0032418	lysosome localization(GO:0032418)
1.1	15.5	GO:0007080	mitotic metaphase plate congression(GO:0007080)
1.1	79.9	GO:0070527	platelet aggregation(GO:0070527)
1.1	5.5	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
1.1	10.9	GO:0030261	chromosome condensation(GO:0030261)
1.1	3.3	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
1.1	46.5	GO:0007062	sister chromatid cohesion(GO:0007062)
1.1	8.6	GO:0030497	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
1.1	15.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
1.1	8.6	GO:0032482	Rab protein signal transduction(GO:0032482)
1.1	58.7	GO:0032465	regulation of cytokinesis(GO:0032465)
1.1	6.4	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
1.1	117.2	GO:0070268	cornification(GO:0070268)
1.1	29.6	GO:0036297	interstrand cross-link repair(GO:0036297)
1.0	114.7	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
1.0	17.7	GO:0030488	tRNA methylation(GO:0030488)
1.0	20.8	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
1.0	19.6	GO:0051893	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of adherens junction organization(GO:1903391)
1.0	8.3	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
1.0	10.2	GO:0070828	heterochromatin organization(GO:0070828)
1.0	6.1	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
1.0	56.5	GO:0045454	cell redox homeostasis(GO:0045454)
1.0	10.1	GO:0009650	UV protection(GO:0009650)
1.0	5.0	GO:2000035	regulation of stem cell division(GO:2000035)
1.0	18.9	GO:0031648	protein destabilization(GO:0031648)
1.0	4.9	GO:0075525	viral translational termination-reinitiation(GO:0075525)
1.0	11.6	GO:0030050	vesicle transport along actin filament(GO:0030050)
1.0	10.5	GO:0035561	regulation of chromatin binding(GO:0035561)
1.0	8.6	GO:0031053	primary miRNA processing(GO:0031053)
1.0	15.2	GO:0017145	stem cell division(GO:0017145)
0.9	2.8	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.9	99.0	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.9	11.2	GO:0030252	growth hormone secretion(GO:0030252)
0.9	10.2	GO:0006903	vesicle targeting(GO:0006903)
0.9	31.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.9	7.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.9	49.8	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.9	34.1	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.9	7.7	GO:0051351	positive regulation of ligase activity(GO:0051351)
0.8	26.1	GO:0008033	tRNA processing(GO:0008033)
0.8	12.6	GO:0008105	asymmetric protein localization(GO:0008105)
0.8	12.2	GO:0000338	protein deneddylation(GO:0000338)
0.8	5.6	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.8	2.4	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.8	3.2	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.8	3.2	GO:0051138	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.8	5.5	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.8	7.7	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.8	3.8	GO:0003070	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.7	8.2	GO:0030335	positive regulation of cell migration(GO:0030335)
0.7	10.3	GO:0072697	protein localization to cell cortex(GO:0072697)
0.7	8.8	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.7	4.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.7	16.6	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.7	1.4	GO:0034773	histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.7	2.0	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.7	9.3	GO:0044804	nucleophagy(GO:0044804)
0.7	4.6	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.7	21.0	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.7	10.5	GO:0032508	DNA duplex unwinding(GO:0032508)
0.7	2.6	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.7	38.5	GO:0006364	rRNA processing(GO:0006364) rRNA metabolic process(GO:0016072)
0.7	1.3	GO:1903061	positive regulation of lipoprotein metabolic process(GO:0050747) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.6	4.4	GO:0019068	virion assembly(GO:0019068)
0.6	5.6	GO:0097264	self proteolysis(GO:0097264)
0.6	2.5	GO:0003409	optic cup structural organization(GO:0003409)
0.6	11.3	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.6	2.4	GO:0061635	regulation of protein complex stability(GO:0061635)
0.6	4.1	GO:0001701	in utero embryonic development(GO:0001701)
0.6	16.9	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.6	6.4	GO:0001649	osteoblast differentiation(GO:0001649)
0.6	4.6	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.6	93.6	GO:0006457	protein folding(GO:0006457)
0.6	18.8	GO:0050819	negative regulation of coagulation(GO:0050819)
0.5	3.8	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.5	0.5	GO:0007135	meiosis II(GO:0007135) meiotic sister chromatid segregation(GO:0045144)
0.5	9.5	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.5	1.0	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.5	21.0	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.4	4.4	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.4	10.4	GO:0097120	receptor localization to synapse(GO:0097120)
0.4	18.5	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.4	3.4	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.4	44.6	GO:0008213	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.4	2.5	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.4	7.5	GO:1901796	regulation of signal transduction by p53 class mediator(GO:1901796)
0.4	5.7	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.4	11.4	GO:0006342	chromatin silencing(GO:0006342)
0.4	4.9	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.4	3.3	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.4	23.1	GO:0031100	organ regeneration(GO:0031100)
0.4	1.1	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.4	2.5	GO:0008218	bioluminescence(GO:0008218)
0.4	18.6	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.3	2.4	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.3	5.4	GO:0032060	bleb assembly(GO:0032060)
0.3	34.2	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.3	0.6	GO:1903214	regulation of protein targeting to mitochondrion(GO:1903214)
0.3	4.9	GO:0016579	protein deubiquitination(GO:0016579)
0.3	0.9	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.3	5.4	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.3	1.2	GO:0038203	TORC2 signaling(GO:0038203)
0.3	0.3	GO:0098917	retrograde trans-synaptic signaling(GO:0098917)
0.3	9.8	GO:0007031	peroxisome organization(GO:0007031)
0.3	2.9	GO:0098877	neurotransmitter receptor transport to plasma membrane(GO:0098877)
0.2	7.9	GO:0016575	histone deacetylation(GO:0016575)
0.2	0.7	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2	1.0	GO:0002021	response to dietary excess(GO:0002021)
0.2	2.8	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.2	1.1	GO:1903844	regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.2	2.9	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.2	2.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.2	11.7	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.2	9.9	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.2	7.4	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2	1.2	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.2	3.3	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.2	7.9	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.2	0.9	GO:0042118	endothelial cell activation(GO:0042118)
0.2	0.5	GO:0015791	polyol transport(GO:0015791)
0.2	4.8	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.2	6.9	GO:0051492	regulation of stress fiber assembly(GO:0051492)
0.2	3.7	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.2	2.4	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.2	20.9	GO:0030336	negative regulation of cell migration(GO:0030336)
0.2	2.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2	14.0	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	0.1	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.1	0.3	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	0.5	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.1	6.2	GO:0007224	smoothened signaling pathway(GO:0007224)
0.1	1.4	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.1	2.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	3.5	GO:0055007	cardiac muscle cell differentiation(GO:0055007)
0.1	0.8	GO:0048636	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	1.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	3.4	GO:0007265	Ras protein signal transduction(GO:0007265)
0.0	1.5	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.4	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.3	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.2	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.9	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.2	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.7	GO:0050729	positive regulation of inflammatory response(GO:0050729)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
41.0	205.2	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
39.6	277.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
33.6	168.1	GO:0043564	Ku70:Ku80 complex(GO:0043564)
33.6	403.5	GO:0005642	annulate lamellae(GO:0005642)
33.4	100.2	GO:0005715	late recombination nodule(GO:0005715)
32.7	130.8	GO:0000798	nuclear cohesin complex(GO:0000798)
28.3	141.3	GO:0032021	NELF complex(GO:0032021)
27.4	273.6	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
26.2	78.6	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
26.1	104.2	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
25.4	177.9	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
25.0	74.9	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
24.6	98.3	GO:0031510	SUMO activating enzyme complex(GO:0031510)
24.0	120.0	GO:0035370	UBC13-UEV1A complex(GO:0035370)
23.3	279.8	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
21.7	65.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
20.6	618.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
20.4	265.3	GO:0002199	zona pellucida receptor complex(GO:0002199)
19.9	159.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
19.8	98.8	GO:0001940	male pronucleus(GO:0001940)
19.5	97.3	GO:0000408	EKC/KEOPS complex(GO:0000408)
17.9	53.7	GO:0070557	PCNA-p21 complex(GO:0070557)
17.8	53.5	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
17.4	52.2	GO:1903349	omegasome membrane(GO:1903349)
17.3	138.6	GO:0042382	paraspeckles(GO:0042382)
16.4	49.3	GO:0032302	MutSbeta complex(GO:0032302)
16.0	111.8	GO:0000172	ribonuclease MRP complex(GO:0000172)
15.8	79.0	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
15.7	283.0	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
15.7	47.1	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
15.7	47.0	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
15.2	121.8	GO:0031931	TORC1 complex(GO:0031931)
15.0	60.2	GO:0001405	presequence translocase-associated import motor(GO:0001405)
14.9	238.2	GO:0031080	nuclear pore outer ring(GO:0031080)
14.4	143.7	GO:0000796	condensin complex(GO:0000796)
14.3	114.4	GO:0070552	BRISC complex(GO:0070552)
14.3	128.7	GO:0005827	polar microtubule(GO:0005827)
14.0	83.9	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
13.5	94.7	GO:0031415	NatA complex(GO:0031415)
13.4	174.5	GO:0000815	ESCRT III complex(GO:0000815)
13.2	39.5	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
11.5	46.1	GO:0031417	NatC complex(GO:0031417)
11.4	125.7	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
11.2	145.3	GO:0000243	commitment complex(GO:0000243)
11.1	121.9	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
10.8	182.8	GO:0031616	spindle pole centrosome(GO:0031616)
10.7	53.5	GO:0097422	tubular endosome(GO:0097422)
10.6	31.9	GO:0043159	acrosomal matrix(GO:0043159)
10.2	112.4	GO:0070765	gamma-secretase complex(GO:0070765)
10.1	30.2	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
10.0	70.3	GO:0046581	intercellular canaliculus(GO:0046581)
9.9	29.8	GO:0043291	RAVE complex(GO:0043291)
9.9	256.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
9.6	105.4	GO:0044666	MLL3/4 complex(GO:0044666)
9.5	113.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
9.4	93.9	GO:0030015	CCR4-NOT core complex(GO:0030015)
9.3	46.3	GO:1990425	ryanodine receptor complex(GO:1990425)
9.2	55.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
9.1	27.4	GO:0019008	molybdopterin synthase complex(GO:0019008)
9.1	91.1	GO:0008290	F-actin capping protein complex(GO:0008290)
8.9	212.6	GO:0046930	pore complex(GO:0046930)
8.8	212.3	GO:0071564	npBAF complex(GO:0071564)
8.7	103.8	GO:0097431	mitotic spindle pole(GO:0097431)
8.5	42.4	GO:0005663	DNA replication factor C complex(GO:0005663)
8.5	237.0	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
8.3	83.3	GO:0097255	R2TP complex(GO:0097255)
8.3	24.9	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
8.2	229.3	GO:0031143	pseudopodium(GO:0031143)
8.2	89.9	GO:0032797	SMN complex(GO:0032797)
8.1	533.9	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
8.1	64.6	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
8.0	217.2	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
8.0	24.1	GO:0032133	chromosome passenger complex(GO:0032133)
7.9	79.4	GO:0030126	COPI vesicle coat(GO:0030126)
7.9	55.0	GO:0070531	BRCA1-A complex(GO:0070531)
7.8	39.2	GO:0097149	centralspindlin complex(GO:0097149)
7.8	46.7	GO:0005688	U6 snRNP(GO:0005688)
7.7	38.4	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
7.5	37.6	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
7.4	29.5	GO:0005726	perichromatin fibrils(GO:0005726)
7.3	36.6	GO:0035061	interchromatin granule(GO:0035061)
7.2	43.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
7.1	35.3	GO:0042643	actomyosin, actin portion(GO:0042643)
7.0	35.2	GO:0031594	neuromuscular junction(GO:0031594)
6.8	54.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
6.7	33.3	GO:0009368	endopeptidase Clp complex(GO:0009368)
6.6	125.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
6.6	65.8	GO:0090543	Flemming body(GO:0090543)
6.4	44.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
6.4	76.5	GO:0031595	nuclear proteasome complex(GO:0031595)
6.3	157.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
6.3	18.8	GO:0072563	endothelial microparticle(GO:0072563)
6.2	18.5	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
6.2	61.7	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
6.1	245.6	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
6.1	85.4	GO:0097227	sperm annulus(GO:0097227)
6.0	90.0	GO:0005869	dynactin complex(GO:0005869)
5.9	17.7	GO:0033565	ESCRT-0 complex(GO:0033565)
5.9	23.6	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
5.9	310.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
5.7	28.6	GO:0034715	pICln-Sm protein complex(GO:0034715)
5.7	68.1	GO:0000346	transcription export complex(GO:0000346)
5.7	96.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
5.6	101.3	GO:0032433	filopodium tip(GO:0032433)
5.6	56.3	GO:0035749	myelin sheath adaxonal region(GO:0035749)
5.6	33.5	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
5.5	33.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
5.4	48.6	GO:0033588	Elongator holoenzyme complex(GO:0033588)
5.2	41.9	GO:0030688	preribosome, small subunit precursor(GO:0030688)
5.2	51.9	GO:0070187	telosome(GO:0070187)
5.1	15.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
5.1	20.4	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
5.0	29.8	GO:0070545	PeBoW complex(GO:0070545)
4.9	34.1	GO:0000812	Swr1 complex(GO:0000812)
4.9	24.3	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
4.8	62.4	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
4.8	19.1	GO:0055087	Ski complex(GO:0055087)
4.7	126.8	GO:0071682	endocytic vesicle lumen(GO:0071682)
4.5	86.3	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
4.5	26.7	GO:1990357	terminal web(GO:1990357)
4.3	21.6	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
4.3	25.8	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
4.2	8.4	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
4.2	29.2	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
4.2	66.6	GO:0071004	U2-type prespliceosome(GO:0071004)
4.1	8.3	GO:0071203	WASH complex(GO:0071203)
4.1	302.4	GO:0005758	mitochondrial intermembrane space(GO:0005758)
4.0	59.8	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
3.9	7.9	GO:0048787	presynaptic active zone membrane(GO:0048787)
3.9	203.6	GO:0045171	intercellular bridge(GO:0045171)
3.9	11.7	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
3.9	27.0	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
3.9	27.0	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
3.8	26.6	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
3.8	15.2	GO:0070876	SOSS complex(GO:0070876)
3.8	45.5	GO:0030008	TRAPP complex(GO:0030008)
3.6	83.2	GO:0017053	transcriptional repressor complex(GO:0017053)
3.6	21.5	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
3.5	24.8	GO:0061617	MICOS complex(GO:0061617)
3.5	10.6	GO:0071159	NF-kappaB complex(GO:0071159)
3.5	24.6	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
3.5	69.1	GO:0005838	proteasome regulatory particle(GO:0005838)
3.4	23.8	GO:0030121	AP-1 adaptor complex(GO:0030121)
3.4	33.8	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
3.4	50.6	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
3.3	13.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
3.3	6.6	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
3.2	28.7	GO:0000439	core TFIIH complex(GO:0000439)
3.2	88.7	GO:0005868	cytoplasmic dynein complex(GO:0005868)
3.2	72.8	GO:0005746	mitochondrial respiratory chain(GO:0005746)
3.1	18.8	GO:0071817	MMXD complex(GO:0071817)
3.1	28.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
3.1	12.4	GO:0032044	DSIF complex(GO:0032044)
3.1	15.5	GO:0071986	Ragulator complex(GO:0071986)
3.0	21.3	GO:1990635	proximal dendrite(GO:1990635)
3.0	74.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
3.0	20.8	GO:0005685	U1 snRNP(GO:0005685)
2.9	20.5	GO:0005956	protein kinase CK2 complex(GO:0005956)
2.9	8.6	GO:0005674	transcription factor TFIIF complex(GO:0005674)
2.8	53.1	GO:0036020	endolysosome membrane(GO:0036020)
2.8	11.0	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
2.8	88.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
2.7	27.0	GO:0030137	COPI-coated vesicle(GO:0030137)
2.6	55.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
2.6	12.9	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
2.6	20.5	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
2.5	130.0	GO:0072686	mitotic spindle(GO:0072686)
2.5	27.4	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
2.5	32.2	GO:0008385	IkappaB kinase complex(GO:0008385)
2.5	29.7	GO:0042555	MCM complex(GO:0042555)
2.5	9.8	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
2.4	102.4	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
2.4	33.3	GO:0031970	organelle envelope lumen(GO:0031970)
2.3	7.0	GO:0005607	laminin-2 complex(GO:0005607)
2.3	34.7	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
2.3	6.9	GO:0060091	kinocilium(GO:0060091) kinociliary basal body(GO:1902636)
2.3	29.8	GO:0071011	precatalytic spliceosome(GO:0071011)
2.3	104.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
2.3	25.0	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.3	15.8	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
2.3	38.3	GO:0032059	bleb(GO:0032059)
2.2	29.2	GO:0031209	SCAR complex(GO:0031209)
2.2	64.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
2.2	15.5	GO:0016272	prefoldin complex(GO:0016272)
2.2	11.0	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.2	15.2	GO:0035253	ciliary rootlet(GO:0035253)
2.2	97.6	GO:0000502	proteasome complex(GO:0000502)
2.2	51.7	GO:0002080	acrosomal membrane(GO:0002080)
2.1	332.2	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
2.1	46.5	GO:0005721	pericentric heterochromatin(GO:0005721)
2.0	24.5	GO:0000118	histone deacetylase complex(GO:0000118)
2.0	22.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
2.0	18.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.0	76.3	GO:0005844	polysome(GO:0005844)
2.0	33.9	GO:0005720	nuclear heterochromatin(GO:0005720)
2.0	27.9	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
2.0	49.8	GO:0005640	nuclear outer membrane(GO:0005640)
2.0	211.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
2.0	185.4	GO:0005840	ribosome(GO:0005840)
1.9	15.6	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
1.9	34.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
1.8	29.9	GO:0097526	spliceosomal tri-snRNP complex(GO:0097526)
1.8	10.5	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
1.7	59.3	GO:0031258	lamellipodium membrane(GO:0031258)
1.7	15.5	GO:0070419	nonhomologous end joining complex(GO:0070419)
1.7	11.9	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
1.7	13.6	GO:0030057	desmosome(GO:0030057)
1.7	6.7	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.7	33.4	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.6	18.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
1.6	109.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.5	4.5	GO:0089701	U2AF(GO:0089701)
1.5	19.0	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
1.4	2.9	GO:0072487	MSL complex(GO:0072487)
1.4	5.7	GO:1990075	periciliary membrane compartment(GO:1990075)
1.4	14.3	GO:0030127	COPII vesicle coat(GO:0030127)
1.4	71.8	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
1.4	4.2	GO:0031213	RSF complex(GO:0031213)
1.4	6.9	GO:0031514	motile cilium(GO:0031514)
1.3	5.4	GO:0070469	respiratory chain(GO:0070469)
1.3	5.3	GO:0032593	insulin-responsive compartment(GO:0032593)
1.3	32.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
1.3	170.4	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
1.3	29.0	GO:0005921	gap junction(GO:0005921)
1.2	11.9	GO:0030686	90S preribosome(GO:0030686)
1.2	14.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
1.2	10.5	GO:0097470	ribbon synapse(GO:0097470)
1.2	15.0	GO:0035577	azurophil granule membrane(GO:0035577)
1.1	10.3	GO:0044292	dendrite terminus(GO:0044292)
1.1	89.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
1.1	22.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
1.1	5.3	GO:0032039	integrator complex(GO:0032039)
1.1	3.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
1.0	247.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
1.0	4.1	GO:0005846	nuclear cap binding complex(GO:0005846)
1.0	4.9	GO:0032389	MutLalpha complex(GO:0032389)
1.0	110.3	GO:0035579	specific granule membrane(GO:0035579)
1.0	6.7	GO:0000813	ESCRT I complex(GO:0000813)
1.0	51.5	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.9	8.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.9	20.0	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.9	101.9	GO:0016605	PML body(GO:0016605)
0.9	5.2	GO:0015629	actin cytoskeleton(GO:0015629)
0.9	10.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.8	14.3	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.8	24.4	GO:0016363	nuclear matrix(GO:0016363)
0.8	27.3	GO:0043198	dendritic shaft(GO:0043198)
0.7	6.7	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.7	2.9	GO:0005686	U2 snRNP(GO:0005686)
0.7	23.7	GO:0008180	COP9 signalosome(GO:0008180)
0.7	18.6	GO:0097228	sperm principal piece(GO:0097228)
0.7	3.4	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.7	3.3	GO:0005899	insulin receptor complex(GO:0005899)
0.7	47.0	GO:0014704	intercalated disc(GO:0014704)
0.7	54.5	GO:0031902	late endosome membrane(GO:0031902)
0.7	7.8	GO:0032591	dendritic spine membrane(GO:0032591)
0.7	265.7	GO:0005925	focal adhesion(GO:0005925)
0.6	12.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.6	5.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.6	17.8	GO:0005680	anaphase-promoting complex(GO:0005680)
0.6	3.0	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.6	54.6	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.6	25.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.6	1.7	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.6	4.5	GO:0030904	retromer complex(GO:0030904)
0.6	8.4	GO:0000242	pericentriolar material(GO:0000242)
0.5	13.6	GO:0044815	DNA packaging complex(GO:0044815)
0.5	0.5	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.5	18.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.5	68.2	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.4	9.8	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.4	10.4	GO:0001772	immunological synapse(GO:0001772)
0.4	12.5	GO:0005913	cell-cell adherens junction(GO:0005913)
0.3	1.7	GO:0005902	microvillus(GO:0005902)
0.3	5.3	GO:0035861	site of double-strand break(GO:0035861)
0.3	752.1	GO:0070062	extracellular exosome(GO:0070062)
0.3	9.9	GO:0030315	T-tubule(GO:0030315)
0.2	7.0	GO:0005901	caveola(GO:0005901)
0.2	28.1	GO:0031966	mitochondrial membrane(GO:0031966)
0.2	2.0	GO:0097346	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.2	1.1	GO:0002102	podosome(GO:0002102)
0.2	0.5	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	3.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	2.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	3.3	GO:0036379	myofilament(GO:0036379)
0.1	5.5	GO:0030018	Z disc(GO:0030018)
0.1	1.5	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.1	44.3	GO:0005739	mitochondrion(GO:0005739)
0.1	1.0	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.3	GO:0043196	varicosity(GO:0043196)
0.0	2.7	GO:0030027	lamellipodium(GO:0030027)
0.0	1.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.6	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
52.7	369.0	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
41.9	125.6	GO:0070260	tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
34.7	104.2	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
31.4	31.4	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
30.3	424.8	GO:0030957	Tat protein binding(GO:0030957)
29.5	88.6	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
29.5	88.4	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
27.4	273.6	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
27.3	573.3	GO:0001055	RNA polymerase II activity(GO:0001055)
27.3	245.5	GO:0015288	porin activity(GO:0015288)
26.7	80.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
24.9	99.4	GO:0031871	proteinase activated receptor binding(GO:0031871)
22.8	68.5	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
22.6	428.5	GO:0017070	U6 snRNA binding(GO:0017070)
22.5	112.6	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
20.6	103.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
20.4	61.2	GO:0010698	acetyltransferase activator activity(GO:0010698)
20.0	100.2	GO:0032137	guanine/thymine mispair binding(GO:0032137)
19.4	19.4	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
19.1	114.8	GO:0016531	copper chaperone activity(GO:0016531)
18.7	56.0	GO:0003883	CTP synthase activity(GO:0003883)
18.6	55.7	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
17.7	70.7	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
17.6	176.5	GO:0051425	PTB domain binding(GO:0051425)
17.3	17.3	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
17.0	102.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
17.0	68.1	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
16.9	118.5	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
16.8	168.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
16.4	131.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
16.3	114.4	GO:0004793	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
16.3	48.8	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
16.2	48.6	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
15.9	47.8	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
15.8	31.5	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
15.7	47.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
14.9	14.9	GO:0051536	iron-sulfur cluster binding(GO:0051536) 4 iron, 4 sulfur cluster binding(GO:0051539) metal cluster binding(GO:0051540)
14.7	58.7	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
14.7	146.5	GO:1990446	U1 snRNP binding(GO:1990446)
14.3	86.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
14.3	57.3	GO:0004427	inorganic diphosphatase activity(GO:0004427)
13.9	41.8	GO:0016749	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
13.4	134.2	GO:0030911	TPR domain binding(GO:0030911)
13.1	39.4	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
13.1	39.3	GO:0070361	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
12.9	38.8	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
12.9	64.6	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
12.9	64.5	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
12.6	88.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
12.2	48.9	GO:0002060	purine nucleobase binding(GO:0002060)
11.8	23.6	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
11.6	139.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
11.6	92.6	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
11.4	34.3	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
11.4	159.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
11.4	113.6	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
11.2	33.7	GO:0033149	FFAT motif binding(GO:0033149)
11.2	33.6	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
11.2	78.2	GO:1990226	histone methyltransferase binding(GO:1990226)
11.1	55.6	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
10.8	53.9	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
10.7	53.5	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
10.6	31.9	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
10.6	84.9	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
10.6	63.7	GO:0019776	Atg8 ligase activity(GO:0019776)
10.6	31.7	GO:0046921	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
10.5	42.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
10.5	31.4	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
10.4	20.8	GO:0070990	snRNP binding(GO:0070990)
10.4	62.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
10.1	30.2	GO:0045134	uridine-diphosphatase activity(GO:0045134)
10.0	60.2	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
9.9	267.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
9.7	252.7	GO:0008266	poly(U) RNA binding(GO:0008266)
9.5	503.2	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
9.3	56.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
9.3	56.0	GO:0044547	DNA topoisomerase binding(GO:0044547)
9.3	74.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
9.2	55.3	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
9.1	27.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
9.1	27.4	GO:0030366	molybdopterin synthase activity(GO:0030366)
9.1	273.7	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
9.1	72.4	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
9.0	125.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
8.9	26.8	GO:0004828	serine-tRNA ligase activity(GO:0004828)
8.9	35.7	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
8.9	44.4	GO:0015140	malate transmembrane transporter activity(GO:0015140)
8.9	8.9	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
8.8	35.4	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
8.6	25.8	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
8.4	25.2	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
8.3	24.9	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
8.2	57.6	GO:0047134	protein-disulfide reductase activity(GO:0047134)
8.2	342.5	GO:0004532	exoribonuclease activity(GO:0004532)
8.0	120.5	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
8.0	56.1	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
7.9	31.6	GO:0035613	RNA stem-loop binding(GO:0035613)
7.8	47.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
7.7	30.9	GO:0043515	kinetochore binding(GO:0043515)
7.4	268.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
7.3	51.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
7.3	21.9	GO:0045322	unmethylated CpG binding(GO:0045322)
7.2	50.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
7.1	28.5	GO:0019826	oxygen sensor activity(GO:0019826)
7.1	49.4	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
7.0	76.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
6.9	62.2	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
6.7	33.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
6.6	171.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
6.4	51.3	GO:0070087	chromo shadow domain binding(GO:0070087)
6.4	102.4	GO:0004526	ribonuclease P activity(GO:0004526)
6.3	44.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
6.2	55.9	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
6.2	283.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
6.0	24.2	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
6.0	42.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
5.8	58.0	GO:0015266	protein channel activity(GO:0015266)
5.8	46.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
5.6	33.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
5.6	11.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
5.5	66.5	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
5.5	65.9	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
5.4	54.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
5.3	42.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
5.2	110.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
5.2	10.5	GO:0015616	DNA translocase activity(GO:0015616)
5.2	114.7	GO:0016881	acid-amino acid ligase activity(GO:0016881)
5.2	31.0	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
5.0	14.9	GO:0051880	G-quadruplex DNA binding(GO:0051880)
4.9	44.5	GO:0070878	primary miRNA binding(GO:0070878)
4.9	34.0	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
4.9	92.4	GO:0050811	GABA receptor binding(GO:0050811)
4.8	188.3	GO:0031593	polyubiquitin binding(GO:0031593)
4.8	38.6	GO:0034603	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
4.8	57.5	GO:0089720	caspase binding(GO:0089720)
4.8	194.9	GO:0042974	retinoic acid receptor binding(GO:0042974)
4.7	23.6	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
4.6	13.9	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
4.6	23.0	GO:0000339	RNA cap binding(GO:0000339)
4.5	320.6	GO:0003743	translation initiation factor activity(GO:0003743)
4.5	13.5	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
4.5	147.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
4.4	70.3	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
4.3	155.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
4.3	47.5	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
4.3	38.7	GO:0035174	histone serine kinase activity(GO:0035174)
4.2	126.5	GO:0000993	RNA polymerase II core binding(GO:0000993)
4.2	41.7	GO:0070053	thrombospondin receptor activity(GO:0070053)
4.1	16.6	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
4.1	20.7	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
4.1	28.8	GO:0008097	5S rRNA binding(GO:0008097)
4.1	32.5	GO:0016929	SUMO-specific protease activity(GO:0016929)
4.0	72.5	GO:0008143	poly(A) binding(GO:0008143)
4.0	40.1	GO:0070182	DNA polymerase binding(GO:0070182)
4.0	27.9	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
3.9	15.8	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
3.9	27.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
3.9	92.7	GO:0070410	co-SMAD binding(GO:0070410)
3.8	56.6	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
3.8	18.8	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
3.7	85.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
3.7	62.8	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
3.6	18.2	GO:1990460	leptin receptor binding(GO:1990460)
3.5	10.6	GO:0031859	platelet activating factor receptor binding(GO:0031859)
3.5	7.0	GO:0038025	reelin receptor activity(GO:0038025)
3.5	13.9	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
3.4	175.8	GO:0019213	deacetylase activity(GO:0019213)
3.4	47.8	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
3.3	60.0	GO:0045505	dynein intermediate chain binding(GO:0045505)
3.3	16.5	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
3.3	65.7	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
3.3	9.8	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
3.3	22.9	GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
3.3	91.1	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
3.2	15.8	GO:0004771	sterol esterase activity(GO:0004771)
3.1	122.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
3.1	9.4	GO:0034511	U3 snoRNA binding(GO:0034511)
3.1	15.6	GO:0050815	phosphoserine binding(GO:0050815)
3.1	62.2	GO:0005537	mannose binding(GO:0005537)
3.1	49.6	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
3.1	12.3	GO:0008174	mRNA methyltransferase activity(GO:0008174)
3.0	15.2	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158) enhancer binding(GO:0035326)
3.0	30.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
3.0	11.9	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
2.9	20.6	GO:0000182	rDNA binding(GO:0000182)
2.9	11.6	GO:0016936	galactoside binding(GO:0016936)
2.9	8.6	GO:0033130	acetylcholine receptor binding(GO:0033130)
2.9	60.0	GO:0070403	NAD+ binding(GO:0070403)
2.8	67.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
2.8	41.7	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
2.7	16.1	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
2.6	12.9	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
2.6	36.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
2.6	7.7	GO:0032184	SUMO polymer binding(GO:0032184)
2.6	38.6	GO:0017160	Ral GTPase binding(GO:0017160)
2.6	10.3	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
2.6	28.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
2.5	15.2	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.5	528.9	GO:0003735	structural constituent of ribosome(GO:0003735)
2.5	27.5	GO:0016421	CoA carboxylase activity(GO:0016421)
2.5	40.0	GO:0097602	cullin family protein binding(GO:0097602)
2.4	9.7	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
2.4	19.4	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
2.4	14.4	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
2.4	60.0	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
2.4	64.7	GO:0070064	proline-rich region binding(GO:0070064)
2.4	45.5	GO:0003746	translation elongation factor activity(GO:0003746)
2.4	7.2	GO:0015235	cobalamin transporter activity(GO:0015235)
2.4	7.2	GO:0004020	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
2.4	7.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.4	23.8	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
2.4	19.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
2.3	27.9	GO:0001056	RNA polymerase III activity(GO:0001056)
2.3	229.7	GO:0008565	protein transporter activity(GO:0008565)
2.3	6.9	GO:0005137	interleukin-5 receptor binding(GO:0005137)
2.3	32.2	GO:0008432	JUN kinase binding(GO:0008432)
2.3	74.9	GO:0000049	tRNA binding(GO:0000049)
2.3	22.7	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
2.2	6.7	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
2.2	61.8	GO:0051059	NF-kappaB binding(GO:0051059)
2.2	24.0	GO:0031996	thioesterase binding(GO:0031996)
2.2	36.9	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
2.2	17.4	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
2.1	62.3	GO:0031210	phosphatidylcholine binding(GO:0031210)
2.1	116.8	GO:0043130	ubiquitin binding(GO:0043130)
2.1	40.2	GO:0032794	GTPase activating protein binding(GO:0032794)
2.1	40.1	GO:0031491	nucleosome binding(GO:0031491)
2.1	27.4	GO:0016004	phospholipase activator activity(GO:0016004)
2.1	29.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
2.1	16.7	GO:0008135	translation factor activity, RNA binding(GO:0008135)
2.1	45.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.1	68.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
2.0	24.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
2.0	6.0	GO:0030984	kininogen binding(GO:0030984)
1.9	11.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
1.9	75.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
1.9	3.8	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.9	22.5	GO:0043022	ribosome binding(GO:0043022)
1.9	91.2	GO:0035064	methylated histone binding(GO:0035064)
1.9	29.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
1.9	64.9	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
1.8	53.2	GO:0005540	hyaluronic acid binding(GO:0005540)
1.8	49.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
1.8	124.1	GO:0008276	protein methyltransferase activity(GO:0008276)
1.7	19.1	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
1.7	13.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
1.7	18.7	GO:0004312	fatty acid synthase activity(GO:0004312)
1.7	6.7	GO:0097157	pre-mRNA intronic binding(GO:0097157)
1.7	43.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
1.6	88.8	GO:0002039	p53 binding(GO:0002039)
1.5	254.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
1.5	42.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
1.5	4.5	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
1.5	64.0	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
1.4	130.4	GO:0051082	unfolded protein binding(GO:0051082)
1.4	26.8	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
1.4	16.7	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
1.4	19.4	GO:0070513	death domain binding(GO:0070513)
1.4	5.5	GO:0004966	galanin receptor activity(GO:0004966)
1.3	13.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.3	22.1	GO:0036002	pre-mRNA binding(GO:0036002)
1.2	8.4	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
1.2	7.2	GO:0048156	tau protein binding(GO:0048156)
1.2	8.2	GO:0043559	insulin binding(GO:0043559)
1.2	15.2	GO:0017091	AU-rich element binding(GO:0017091)
1.1	6.7	GO:0017018	myosin phosphatase activity(GO:0017018)
1.1	17.8	GO:0004659	prenyltransferase activity(GO:0004659)
1.1	5.4	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
1.1	15.1	GO:0042043	neurexin family protein binding(GO:0042043)
1.0	22.3	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.0	40.2	GO:0042826	histone deacetylase binding(GO:0042826)
1.0	18.8	GO:0004859	phospholipase inhibitor activity(GO:0004859)
1.0	18.7	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.9	12.1	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.9	41.8	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.9	31.5	GO:0019894	kinesin binding(GO:0019894)
0.9	8.0	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.9	8.8	GO:0008252	nucleotidase activity(GO:0008252)
0.9	2.6	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.8	12.7	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.8	8.4	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.8	17.6	GO:0008242	omega peptidase activity(GO:0008242)
0.8	36.1	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.8	5.0	GO:0098821	BMP receptor activity(GO:0098821)
0.8	2.5	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.8	8.7	GO:0019211	phosphatase activator activity(GO:0019211)
0.8	33.9	GO:0003727	single-stranded RNA binding(GO:0003727)
0.8	2.3	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.8	12.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.8	16.3	GO:0019903	protein phosphatase binding(GO:0019903)
0.8	1.5	GO:0019237	centromeric DNA binding(GO:0019237)
0.8	200.9	GO:0044389	ubiquitin-like protein ligase binding(GO:0044389)
0.8	25.9	GO:0030331	estrogen receptor binding(GO:0030331)
0.8	3.0	GO:0051393	actinin binding(GO:0042805) alpha-actinin binding(GO:0051393)
0.7	10.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.7	13.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.7	10.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7	3.4	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.6	5.8	GO:0008158	hedgehog receptor activity(GO:0008158)
0.6	17.9	GO:0000149	SNARE binding(GO:0000149)
0.6	18.9	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.6	1.7	GO:0030332	cyclin binding(GO:0030332)
0.6	15.0	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.6	22.4	GO:0043531	ADP binding(GO:0043531)
0.5	19.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.5	7.5	GO:0009881	photoreceptor activity(GO:0009881)
0.5	10.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.5	10.9	GO:0033613	activating transcription factor binding(GO:0033613)
0.5	2.4	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5	4.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.5	31.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.5	10.5	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.5	3.8	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5	8.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.5	79.8	GO:0051015	actin filament binding(GO:0051015)
0.5	16.7	GO:0030145	manganese ion binding(GO:0030145)
0.4	2.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.4	3.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4	23.0	GO:0005507	copper ion binding(GO:0005507)
0.4	22.3	GO:0051087	chaperone binding(GO:0051087)
0.4	5.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4	71.8	GO:0003779	actin binding(GO:0003779)
0.4	94.7	GO:0045296	cadherin binding(GO:0045296)
0.4	29.5	GO:0019905	syntaxin binding(GO:0019905)
0.4	7.0	GO:0071889	14-3-3 protein binding(GO:0071889)
0.3	3.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.3	3.0	GO:0019902	phosphatase binding(GO:0019902)
0.3	0.6	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.3	12.6	GO:0008009	chemokine activity(GO:0008009)
0.3	4.0	GO:0046527	glucosyltransferase activity(GO:0046527)
0.3	56.8	GO:0030246	carbohydrate binding(GO:0030246)
0.2	23.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.2	3.6	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.2	2.4	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.2	5.6	GO:0004806	triglyceride lipase activity(GO:0004806)
0.2	5.5	GO:0005080	protein kinase C binding(GO:0005080)
0.2	11.7	GO:0017022	myosin binding(GO:0017022)
0.2	0.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2	3.2	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.2	3.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2	11.7	GO:0030165	PDZ domain binding(GO:0030165)
0.1	0.9	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.5	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	3.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	4.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	1.9	GO:0031072	heat shock protein binding(GO:0031072)
0.1	14.3	GO:0019207	kinase regulator activity(GO:0019207)
0.1	0.5	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.1	2.6	GO:0005109	frizzled binding(GO:0005109)
0.1	1.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	8.5	GO:0005178	integrin binding(GO:0005178)
0.1	7.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	2.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	70.3	GO:0003723	RNA binding(GO:0003723)
0.1	1.5	GO:0030276	clathrin binding(GO:0030276)
0.1	5.7	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	1.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	1.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	1.7	GO:0008237	metallopeptidase activity(GO:0008237)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.9	516.2	PID BARD1 PATHWAY	BARD1 signaling events
9.9	227.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
9.6	652.8	PID PLK1 PATHWAY	PLK1 signaling events
6.0	385.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
4.3	137.8	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
3.8	199.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
3.8	191.9	PID AURORA B PATHWAY	Aurora B signaling
3.7	114.5	PID ATM PATHWAY	ATM pathway
3.7	114.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
3.4	288.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
3.3	133.6	PID CD40 PATHWAY	CD40/CD40L signaling
3.3	66.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
3.2	194.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
3.0	27.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
2.9	318.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
2.9	167.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
2.9	31.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
2.6	62.0	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
2.5	166.1	PID RB 1PATHWAY	Regulation of retinoblastoma protein
2.5	72.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
2.4	55.8	PID FANCONI PATHWAY	Fanconi anemia pathway
2.4	116.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
2.2	79.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
2.2	10.8	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
2.1	92.4	PID P53 REGULATION PATHWAY	p53 pathway
2.1	275.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
2.0	75.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
1.9	26.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
1.9	148.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
1.8	8.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.7	24.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
1.6	62.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
1.5	60.3	PID IL1 PATHWAY	IL1-mediated signaling events
1.5	10.6	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
1.4	6.9	PID IL5 PATHWAY	IL5-mediated signaling events
1.4	18.9	ST G ALPHA S PATHWAY	G alpha s Pathway
1.3	6.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.1	53.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
1.1	35.2	PID CDC42 PATHWAY	CDC42 signaling events
1.1	22.9	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
1.1	29.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
1.1	19.0	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
1.0	17.7	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
1.0	23.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
1.0	15.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
1.0	51.8	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
1.0	51.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.9	38.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.8	42.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.8	3.3	PID IGF1 PATHWAY	IGF1 pathway
0.8	14.5	PID ARF 3PATHWAY	Arf1 pathway
0.8	12.5	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.7	50.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.7	8.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.7	4.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.7	6.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.7	50.8	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.6	5.8	PID S1P S1P1 PATHWAY	S1P1 pathway
0.6	24.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.6	5.0	PID BMP PATHWAY	BMP receptor signaling
0.6	14.4	PID RHOA PATHWAY	RhoA signaling pathway
0.5	22.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.5	30.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.5	24.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.4	12.8	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.4	6.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.4	14.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.4	3.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.3	14.5	PID E2F PATHWAY	E2F transcription factor network
0.2	3.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	7.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	5.5	PID FGF PATHWAY	FGF signaling pathway
0.1	1.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	1.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	1.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	0.9	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	12.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	3.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
19.5	467.5	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
18.7	298.7	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
13.5	526.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
12.4	211.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
12.1	108.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
11.6	266.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
10.0	90.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
9.9	19.8	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
9.8	48.9	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
9.6	96.1	REACTOME POL SWITCHING	Genes involved in Polymerase switching
9.6	239.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
9.3	158.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
9.3	289.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
8.7	183.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
8.5	723.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
8.5	153.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
8.3	283.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
8.2	131.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
7.7	123.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
7.7	230.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
7.6	220.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
7.4	657.5	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
7.4	398.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
7.2	7.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
6.7	93.2	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
6.6	26.6	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
6.6	152.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
6.5	38.7	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
6.4	231.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
6.0	299.9	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
5.9	53.1	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
5.8	144.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
5.7	195.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
5.5	82.6	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
5.5	54.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
5.4	107.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
5.4	128.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
5.3	53.0	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
5.1	148.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
5.0	80.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
4.9	116.9	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
4.8	47.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
4.7	51.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
4.7	292.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
4.4	196.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
4.3	82.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
4.1	299.7	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
4.0	272.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
3.8	68.7	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
3.7	78.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
3.7	44.7	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
3.6	332.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
3.5	31.8	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
3.5	27.7	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
3.4	61.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
3.3	46.5	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
3.3	91.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
3.2	51.6	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
3.2	508.6	REACTOME TRANSLATION	Genes involved in Translation
3.2	28.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
3.2	34.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
3.1	61.4	REACTOME KINESINS	Genes involved in Kinesins
3.0	42.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
2.7	285.7	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
2.6	112.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
2.6	99.0	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
2.5	12.4	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
2.5	37.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
2.4	34.0	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
2.4	45.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
2.4	42.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
2.2	69.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
2.1	322.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
2.1	80.3	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
2.0	7.9	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
1.9	52.4	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
1.9	9.4	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
1.8	12.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.8	45.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.8	63.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
1.8	108.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
1.8	23.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.8	35.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
1.7	3.3	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
1.6	27.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.6	44.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
1.5	27.2	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
1.5	4.5	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
1.5	29.8	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
1.4	39.1	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
1.4	25.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
1.3	45.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
1.3	31.5	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
1.2	23.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
1.2	65.5	REACTOME PI METABOLISM	Genes involved in PI Metabolism
1.2	7.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
1.1	23.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.1	10.7	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
1.1	42.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
1.0	12.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
1.0	26.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
1.0	34.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.9	15.8	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.9	31.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.9	56.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.8	27.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.8	17.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.8	10.6	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.7	51.5	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.6	13.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.6	13.8	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.6	18.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.5	87.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.5	22.2	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.4	4.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.4	5.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4	10.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	5.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.3	4.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.3	36.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.3	15.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	2.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	3.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	8.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	2.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	2.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation