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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for OTX1

Z-value: 1.29

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Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
OTX1
ENSG00000115507.5 orthodenticle homeobox 1

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_177631497 31.60 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr11_-_65626753 28.78 ENST00000526975.1
ENST00000531413.1
CFL1
cofilin 1 (non-muscle)
chr12_-_54071181 25.26 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr16_-_58163299 24.04 ENST00000262498.3
C16orf80
chromosome 16 open reading frame 80
chr16_+_33605231 23.59 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_-_85637459 22.09 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr2_-_161350305 22.02 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr4_-_122744998 19.92 ENST00000274026.5
CCNA2
cyclin A2
chr3_+_138340067 19.35 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr19_-_47616992 18.85 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr3_+_138340049 18.00 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr2_-_106054952 16.84 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr2_+_201936707 16.83 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr20_-_33539655 16.29 ENST00000451957.2
GSS
glutathione synthetase
chr9_-_116172946 15.69 ENST00000374171.4
POLE3
polymerase (DNA directed), epsilon 3, accessory subunit
chr1_-_36930012 15.58 ENST00000373116.5
MRPS15
mitochondrial ribosomal protein S15
chr14_-_102552659 15.06 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chrX_-_109561294 14.53 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_+_40723779 14.49 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr3_+_142315225 14.28 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr17_+_41158742 14.11 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr1_-_205719295 13.71 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_+_122513109 13.42 ENST00000389682.3
ENST00000536142.1
TSN
translin
chr19_-_10530784 13.31 ENST00000593124.1
CDC37
cell division cycle 37
chr5_+_135496675 12.98 ENST00000507637.1
SMAD5
SMAD family member 5
chr2_+_201936458 12.88 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr16_-_69373396 12.86 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr5_-_77072085 12.84 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
TBCA
tubulin folding cofactor A
chr6_-_41039567 12.14 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chrX_+_100645812 12.10 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr2_-_74619152 12.08 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr18_+_8717369 11.96 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA2
SOGA family member 2
chr3_-_69129501 11.86 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr6_-_144416737 11.79 ENST00000367569.2
SF3B5
splicing factor 3b, subunit 5, 10kDa
chr17_+_56769924 11.58 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr8_+_101162812 11.27 ENST00000353107.3
ENST00000522439.1
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr22_+_30163340 11.01 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr16_-_29875057 10.95 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chrX_-_134156502 10.68 ENST00000391440.1
FAM127C
family with sequence similarity 127, member C
chr6_-_34393825 10.27 ENST00000605528.1
ENST00000326199.8
RPS10-NUDT3
RPS10
RPS10-NUDT3 readthrough
ribosomal protein S10
chr12_+_20963632 9.99 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr5_+_96038476 9.92 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
CAST
calpastatin
chr12_+_20963647 9.76 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr20_-_32700075 9.44 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr8_+_132916318 9.18 ENST00000254624.5
ENST00000522709.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr3_-_141747950 9.16 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_-_104817919 9.14 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_+_174844645 9.08 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr11_-_67275542 8.89 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr3_+_136649311 8.85 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr4_+_83956237 8.82 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr4_+_83956312 8.72 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr11_-_67276100 8.52 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr12_-_14956396 8.49 ENST00000535328.1
ENST00000261167.2
WBP11
WW domain binding protein 11
chr1_+_74701062 8.44 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr16_-_29874462 8.35 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr12_+_6603253 7.61 ENST00000382457.4
ENST00000545962.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr14_+_21458127 7.58 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17
methyltransferase like 17
chr5_-_111091948 7.46 ENST00000447165.2
NREP
neuronal regeneration related protein
chr8_-_145652336 7.37 ENST00000529182.1
ENST00000526054.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr12_+_57881740 7.26 ENST00000262027.5
ENST00000315473.5
MARS
methionyl-tRNA synthetase
chr6_+_150070857 7.20 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_+_81771806 7.20 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr1_-_9811600 6.94 ENST00000435891.1
CLSTN1
calsyntenin 1
chr11_-_67210930 6.65 ENST00000453768.2
ENST00000545016.1
ENST00000341356.5
CORO1B
coronin, actin binding protein, 1B
chr5_-_54603368 6.63 ENST00000508346.1
ENST00000251636.5
DHX29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr2_-_74618964 6.55 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chrX_+_149861836 6.45 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1
myotubularin related protein 1
chr5_-_81574160 6.37 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
RPS23
ribosomal protein S23
chr1_+_150293921 6.33 ENST00000324862.6
PRPF3
pre-mRNA processing factor 3
chr1_+_109756523 6.10 ENST00000234677.2
ENST00000369923.4
SARS
seryl-tRNA synthetase
chr1_-_89458604 6.05 ENST00000260508.4
CCBL2
cysteine conjugate-beta lyase 2
chr15_-_43876702 5.94 ENST00000348806.6
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr7_-_100895414 5.69 ENST00000435848.1
ENST00000474120.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr1_+_172502336 5.68 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr1_+_150293973 5.62 ENST00000414970.2
ENST00000543398.1
PRPF3
pre-mRNA processing factor 3
chr8_+_109455845 5.48 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr10_+_60028818 5.36 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr19_+_21265028 5.26 ENST00000291770.7
ZNF714
zinc finger protein 714
chr2_-_112642267 5.17 ENST00000341068.3
ANAPC1
anaphase promoting complex subunit 1
chr16_-_8962200 5.05 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr11_-_111957451 4.87 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr7_+_128379346 4.87 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr12_+_100594557 4.82 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr11_-_65626797 4.82 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chr11_-_78052923 4.78 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr9_+_125132803 4.73 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr4_-_83769996 4.51 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr16_-_29874211 4.36 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr14_-_106539557 4.31 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr14_+_50234309 4.22 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr9_+_128509624 4.09 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr1_-_216596738 3.92 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A
Usher syndrome 2A (autosomal recessive, mild)
chr6_+_26251835 3.81 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr14_-_102706934 3.75 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK
MOK protein kinase
chr7_+_128379449 3.73 ENST00000479257.1
CALU
calumenin
chr19_-_41903161 3.69 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr8_-_56986768 3.65 ENST00000523936.1
RPS20
ribosomal protein S20
chr2_+_204103663 3.38 ENST00000356079.4
ENST00000429815.2
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr16_-_21868978 3.29 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chr15_+_42787452 3.21 ENST00000249647.3
SNAP23
synaptosomal-associated protein, 23kDa
chr10_-_35104185 3.20 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr14_-_107170409 3.17 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr2_-_47403642 2.90 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr5_-_39425222 2.80 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr16_+_14802801 2.56 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr6_-_137539651 2.51 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr6_+_26158343 2.47 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chrX_-_148571884 2.38 ENST00000537071.1
IDS
iduronate 2-sulfatase
chr14_-_24911448 2.37 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr12_+_113354341 2.35 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_28764653 2.35 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr16_-_21436459 2.34 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3
nuclear pore complex interacting protein family, member B3
chr14_-_106471723 2.28 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr13_+_38923959 2.16 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr11_-_62420757 2.15 ENST00000330574.2
INTS5
integrator complex subunit 5
chr14_-_107211459 2.10 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr7_-_100239132 2.06 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr18_+_616672 2.05 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr11_+_8704748 1.98 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr5_-_39425290 1.96 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_-_26876350 1.88 ENST00000470125.1
UNC119
unc-119 homolog (C. elegans)
chr16_+_69373323 1.86 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr3_-_45017609 1.85 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
ZDHHC3
zinc finger, DHHC-type containing 3
chr2_-_49381646 1.78 ENST00000346173.3
ENST00000406846.2
FSHR
follicle stimulating hormone receptor
chr1_-_186430222 1.77 ENST00000391997.2
PDC
phosducin
chr16_-_29415350 1.76 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr19_-_42916499 1.65 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr19_+_35940486 1.64 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr4_-_70626314 1.42 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr17_-_36981556 1.34 ENST00000536127.1
ENST00000225428.5
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr8_-_33370607 1.32 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr3_+_11314099 1.30 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr22_+_39052632 1.10 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr2_+_232135245 1.06 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chr13_-_31736478 0.92 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr19_-_3761673 0.71 ENST00000316757.3
APBA3
amyloid beta (A4) precursor protein-binding, family A, member 3
chr18_+_616711 0.68 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chrX_-_43832711 0.50 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr15_-_61521495 0.33 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr8_-_79717750 0.27 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr1_-_151300160 0.21 ENST00000368874.4
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr20_+_48884002 0.13 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr6_+_96025341 0.07 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chr2_+_1418154 0.02 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 33.6 GO:2000812 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
5.0 19.9 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
4.8 14.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
4.0 11.9 GO:0007113 endomitotic cell cycle(GO:0007113)
3.8 15.1 GO:0043335 protein unfolding(GO:0043335)
3.5 17.4 GO:2000035 regulation of stem cell division(GO:2000035)
3.4 13.7 GO:0019046 release from viral latency(GO:0019046)
3.4 16.8 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.0 8.9 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
2.9 14.3 GO:1902896 terminal web assembly(GO:1902896)
2.5 7.4 GO:2000395 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
2.3 18.6 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
2.3 11.6 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
2.2 6.7 GO:1902463 protein localization to cell leading edge(GO:1902463)
2.2 13.0 GO:0001880 Mullerian duct regression(GO:0001880)
2.1 12.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
2.0 6.1 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
1.4 11.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.3 9.4 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
1.3 23.7 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
1.3 1.3 GO:1902534 single-organism membrane invagination(GO:1902534)
1.2 3.7 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
1.2 4.8 GO:0035026 leading edge cell differentiation(GO:0035026)
1.1 5.7 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
1.1 17.5 GO:0000338 protein deneddylation(GO:0000338)
1.1 22.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.0 13.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.0 9.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.0 3.9 GO:0048496 maintenance of organ identity(GO:0048496)
1.0 7.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.9 1.8 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.8 7.2 GO:0030091 protein repair(GO:0030091)
0.8 25.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.8 2.4 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.7 11.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7 16.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.7 9.9 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.7 4.1 GO:0007386 compartment pattern specification(GO:0007386)
0.6 7.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.6 13.3 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.5 1.6 GO:0002752 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.5 15.7 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.5 1.9 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.5 19.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.4 1.8 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.4 28.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 10.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 8.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.4 27.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.4 8.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.3 2.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 5.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 1.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 11.3 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.3 5.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 2.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 0.9 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.3 4.8 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.3 4.4 GO:0006020 inositol metabolic process(GO:0006020)
0.3 5.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 4.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 6.4 GO:0018126 protein hydroxylation(GO:0018126)
0.3 3.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 3.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 12.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 4.9 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 4.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 15.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 9.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 6.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 17.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 16.5 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 22.0 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 5.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 2.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 8.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 2.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 3.0 GO:0006412 translation(GO:0006412)
0.1 6.3 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 20.6 GO:0006260 DNA replication(GO:0006260)
0.0 1.9 GO:0042255 ribosome assembly(GO:0042255)
0.0 6.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 6.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 12.1 GO:0042278 purine nucleoside metabolic process(GO:0042278)
0.0 5.2 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.0 29.7 GO:0043066 negative regulation of apoptotic process(GO:0043066)
0.0 2.1 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.1 GO:0006958 complement activation, classical pathway(GO:0006958)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 19.9 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
3.1 9.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
3.1 15.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
2.4 14.3 GO:1990357 terminal web(GO:1990357)
1.9 11.6 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.9 7.6 GO:0000799 nuclear condensin complex(GO:0000799)
1.5 9.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.5 22.1 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
1.4 25.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.3 3.9 GO:0002139 stereocilia coupling link(GO:0002139)
1.2 18.6 GO:0005869 dynactin complex(GO:0005869)
1.1 7.4 GO:0000813 ESCRT I complex(GO:0000813)
1.0 11.0 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.9 12.9 GO:0017119 Golgi transport complex(GO:0017119)
0.9 33.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.8 8.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.6 11.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.6 16.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.6 4.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6 5.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.6 15.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.6 13.0 GO:0071141 SMAD protein complex(GO:0071141)
0.5 27.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 4.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5 8.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 11.9 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.5 8.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.5 11.8 GO:0005686 U2 snRNP(GO:0005686)
0.5 3.2 GO:0033269 internode region of axon(GO:0033269)
0.4 28.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 7.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 17.5 GO:0008180 COP9 signalosome(GO:0008180)
0.3 16.8 GO:0031430 M band(GO:0031430)
0.3 20.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 2.1 GO:0032039 integrator complex(GO:0032039)
0.2 5.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 14.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 5.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 38.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 4.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 2.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 5.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 14.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 6.3 GO:0000786 nucleosome(GO:0000786)
0.1 3.2 GO:0042629 mast cell granule(GO:0042629)
0.1 3.7 GO:0097546 ciliary base(GO:0097546)
0.1 7.6 GO:0005840 ribosome(GO:0005840)
0.1 1.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.9 GO:0051233 spindle midzone(GO:0051233)
0.1 6.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.8 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 13.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.4 GO:0030027 lamellipodium(GO:0030027)
0.0 30.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.9 GO:0000922 spindle pole(GO:0000922)
0.0 13.7 GO:0005874 microtubule(GO:0005874)
0.0 9.1 GO:0005769 early endosome(GO:0005769)
0.0 7.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 2.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 4.7 GO:0005794 Golgi apparatus(GO:0005794)
0.0 2.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 23.7 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
2.4 7.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.0 6.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.8 8.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.8 17.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.7 9.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.6 11.0 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.5 15.1 GO:0030911 TPR domain binding(GO:0030911)
1.5 11.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.4 11.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.2 4.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.2 16.3 GO:0016594 glycine binding(GO:0016594)
0.9 25.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.9 13.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.9 19.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.9 4.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.8 6.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.8 8.4 GO:0031013 troponin I binding(GO:0031013)
0.7 9.1 GO:0050700 CARD domain binding(GO:0050700)
0.6 11.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.6 1.7 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.5 18.6 GO:0070840 dynein complex binding(GO:0070840)
0.5 15.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 28.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 2.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.5 2.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.5 27.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 6.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.5 6.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.4 1.8 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.4 55.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.4 23.7 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.4 5.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 1.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 2.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.3 35.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.3 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 12.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.3 4.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 16.8 GO:0050681 androgen receptor binding(GO:0050681)
0.2 2.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 50.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 1.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 14.5 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.2 12.1 GO:0019213 deacetylase activity(GO:0019213)
0.2 7.3 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 9.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 6.9 GO:0019894 kinesin binding(GO:0019894)
0.1 13.3 GO:0051087 chaperone binding(GO:0051087)
0.1 1.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 25.0 GO:0051015 actin filament binding(GO:0051015)
0.1 2.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 4.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 4.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 7.4 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 3.9 GO:0017022 myosin binding(GO:0017022)
0.1 8.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 4.9 GO:0003823 antigen binding(GO:0003823)
0.0 3.3 GO:0020037 heme binding(GO:0020037)
0.0 24.6 GO:0003723 RNA binding(GO:0003723)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 7.4 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.9 GO:0042393 histone binding(GO:0042393)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 33.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.8 19.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.7 13.0 PID ALK2 PATHWAY ALK2 signaling events
0.5 11.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.5 16.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.5 23.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.4 42.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.4 18.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 13.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 2.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 7.6 PID AURORA B PATHWAY Aurora B signaling
0.1 9.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 9.2 PID E2F PATHWAY E2F transcription factor network
0.1 3.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 48.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
1.2 19.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.7 19.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7 7.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 13.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.5 11.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.5 12.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 8.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.5 16.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 3.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4 29.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 13.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 29.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 13.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 23.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 4.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 11.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 5.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.2 22.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.2 2.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 4.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 9.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 16.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 6.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.9 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 14.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 10.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 16.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 2.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 4.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 8.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 4.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 3.2 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 4.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane