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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PAX7_NOBOX

Z-value: 1.07

Motif logo

Transcription factors associated with PAX7_NOBOX

Gene Symbol Gene ID Gene Info
ENSG00000009709.7 paired box 7
ENSG00000106410.10 NOBOX oogenesis homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX7hg19_v2_chr1_+_18958008_189580230.544.0e-18Click!

Activity profile of PAX7_NOBOX motif

Sorted Z-values of PAX7_NOBOX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_29171689 23.51 ENST00000237014.3
transthyretin
chr12_-_91546926 22.40 ENST00000550758.1
decorin
chr11_-_76155618 14.72 ENST00000530759.1
RP11-111M22.3
chr1_-_13390765 13.66 ENST00000357367.2
PRAME family member 8
chr11_-_76155700 13.59 ENST00000572035.1
RP11-111M22.3
chr10_-_131909071 12.73 ENST00000456581.1
long intergenic non-protein coding RNA 959
chr14_-_74551096 12.64 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr12_+_26348246 12.36 ENST00000422622.2
sarcospan
chr17_+_1674982 11.94 ENST00000572048.1
ENST00000573763.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr2_+_90248739 11.82 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr4_-_57547870 11.70 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr14_-_74551172 11.67 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr6_-_32095968 11.51 ENST00000375203.3
ENST00000375201.4
activating transcription factor 6 beta
chr6_-_31125850 10.97 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
coiled-coil alpha-helical rod protein 1
chrX_+_43515467 10.71 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr12_-_15038779 10.39 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr1_+_12976450 10.32 ENST00000361079.2
PRAME family member 7
chr4_-_57547454 10.15 ENST00000556376.2
HOP homeobox
chr5_+_66300446 10.11 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr2_+_68962014 9.99 ENST00000467265.1
Rho GTPase activating protein 25
chr7_+_100136811 9.97 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr1_+_1260147 9.85 ENST00000343938.4
glycolipid transfer protein domain containing 1
chr11_-_59383617 9.50 ENST00000263847.1
oxysterol binding protein
chr5_-_95297534 9.28 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr19_+_50016411 8.39 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_76156045 8.29 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
chromosome 11 open reading frame 30
chr14_-_104181771 8.11 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
X-ray repair complementing defective repair in Chinese hamster cells 3
chr17_-_43045439 8.05 ENST00000253407.3
complement component 1, q subcomponent-like 1
chr19_+_50016610 7.85 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_32457176 7.69 ENST00000332351.3
Wilms tumor 1
chr11_-_117748138 7.57 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr5_-_95297678 7.50 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr2_-_89340242 7.44 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr10_-_99447024 7.28 ENST00000370626.3
arginine vasopressin-induced 1
chr14_+_104182061 7.23 ENST00000216602.6
zinc finger, FYVE domain containing 21
chr16_-_66584059 7.23 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr3_+_156544057 7.12 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr5_+_40909354 7.11 ENST00000313164.9
complement component 7
chr14_+_104182105 7.05 ENST00000311141.2
zinc finger, FYVE domain containing 21
chr8_+_9413410 6.95 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chrX_-_92928557 6.88 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr12_+_101988627 6.86 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr11_-_108093329 6.57 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr5_+_130506475 6.56 ENST00000379380.4
LYR motif containing 7
chr19_-_19302931 6.52 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr1_+_12916941 6.34 ENST00000240189.2
PRAME family member 2
chr7_+_100183927 6.31 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr2_-_89292422 6.30 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr11_-_35287243 6.30 ENST00000464522.2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_-_17171817 6.23 ENST00000377833.4
cubilin (intrinsic factor-cobalamin receptor)
chr1_+_44115814 6.21 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr2_+_90077680 6.17 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr3_-_105587879 6.13 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr7_-_100183742 6.12 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr16_+_3493611 5.98 ENST00000407558.4
ENST00000572169.1
ENST00000572757.1
ENST00000573593.1
ENST00000570372.1
ENST00000424546.2
ENST00000575733.1
ENST00000573201.1
ENST00000574950.1
ENST00000573580.1
ENST00000608722.1
N(alpha)-acetyltransferase 60, NatF catalytic subunit
N-alpha-acetyltransferase 60
chr14_-_25078864 5.85 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr22_-_32766972 5.83 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr12_+_101988774 5.82 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr3_-_127317047 5.79 ENST00000462228.1
ENST00000490643.1
transmembrane protein, adipocyte asscociated 1
chr4_-_46911248 5.72 ENST00000355591.3
ENST00000505102.1
cytochrome c oxidase subunit VIIb2
chr3_-_160823158 5.60 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr16_-_28937027 5.55 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chrX_+_77166172 5.43 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr2_+_68961934 5.30 ENST00000409202.3
Rho GTPase activating protein 25
chr4_+_74275057 5.29 ENST00000511370.1
albumin
chr3_-_106959424 5.24 ENST00000607801.1
ENST00000479612.2
ENST00000484698.1
ENST00000477210.2
ENST00000473636.1
long intergenic non-protein coding RNA 882
chr1_-_13452656 5.15 ENST00000376132.3
PRAME family member 13
chr11_-_62521614 5.10 ENST00000527994.1
ENST00000394807.3
zinc finger and BTB domain containing 3
chr19_-_53758094 5.07 ENST00000601828.1
ENST00000598513.1
ENST00000599012.1
ENST00000333952.4
ENST00000598806.1
zinc finger protein 677
chr2_+_90108504 4.97 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_-_27886676 4.96 ENST00000337768.5
suppressor of Ty 7 (S. cerevisiae)-like
chr16_-_66583701 4.96 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
thymidine kinase 2, mitochondrial
chr3_+_46412345 4.95 ENST00000292303.4
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr6_-_167040731 4.95 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr19_+_11485333 4.92 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1
chr17_+_73452695 4.76 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195
chr2_-_3521518 4.71 ENST00000382093.5
acireductone dioxygenase 1
chr2_+_68961905 4.69 ENST00000295381.3
Rho GTPase activating protein 25
chr12_-_45269430 4.67 ENST00000395487.2
NEL-like 2 (chicken)
chr1_+_226013047 4.65 ENST00000366837.4
epoxide hydrolase 1, microsomal (xenobiotic)
chr2_+_90273679 4.64 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr3_-_160823040 4.57 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr10_-_28571015 4.51 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_45270151 4.50 ENST00000429094.2
NEL-like 2 (chicken)
chr12_+_122688090 4.46 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr12_-_45270077 4.45 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr4_+_156587853 4.43 ENST00000506455.1
ENST00000511108.1
guanylate cyclase 1, soluble, alpha 3
chr14_-_52535712 4.32 ENST00000216286.5
ENST00000541773.1
nidogen 2 (osteonidogen)
chr3_+_183903811 4.32 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr2_+_90211643 4.31 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr6_+_28317685 4.26 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr3_+_47324424 4.18 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
kelch-like family member 18
chr1_-_92371839 4.15 ENST00000370399.2
transforming growth factor, beta receptor III
chr3_-_46608010 4.13 ENST00000395905.3
leucine rich repeat containing 2
chr4_-_39033963 4.11 ENST00000381938.3
transmembrane protein 156
chr11_-_33913708 4.06 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr6_+_161123270 4.05 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr2_-_152118352 4.01 ENST00000331426.5
RNA binding motif protein 43
chr1_+_12851545 4.00 ENST00000332296.7
PRAME family member 1
chr14_-_24711806 3.97 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TERF1 (TRF1)-interacting nuclear factor 2
chr12_-_10151773 3.97 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr3_+_149191723 3.92 ENST00000305354.4
transmembrane 4 L six family member 4
chr7_-_99277610 3.91 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr22_-_32767017 3.89 ENST00000400234.1
RFPL3 antisense
chr1_+_152974218 3.87 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
small proline-rich protein 3
chr12_+_26348429 3.84 ENST00000242729.2
sarcospan
chr12_-_114841703 3.81 ENST00000526441.1
T-box 5
chr14_-_24711865 3.80 ENST00000399423.4
ENST00000267415.7
TERF1 (TRF1)-interacting nuclear factor 2
chrX_-_17879356 3.79 ENST00000331511.1
ENST00000415486.3
ENST00000545871.1
ENST00000451717.1
retinoic acid induced 2
chr14_+_74417192 3.77 ENST00000554320.1
coenzyme Q6 monooxygenase
chr3_+_129247479 3.76 ENST00000296271.3
rhodopsin
chr2_-_163008903 3.76 ENST00000418842.2
ENST00000375497.3
glucagon
chr8_+_120885949 3.75 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr17_+_63133587 3.74 ENST00000449996.3
ENST00000262406.9
regulator of G-protein signaling 9
chr19_-_12833361 3.73 ENST00000592287.1
transportin 2
chr2_+_242641442 3.71 ENST00000313552.6
ENST00000406941.1
inhibitor of growth family, member 5
chr8_-_39695719 3.68 ENST00000347580.4
ENST00000379853.2
ENST00000521880.1
ADAM metallopeptidase domain 2
chr2_+_90198535 3.66 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr4_+_88754113 3.62 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr16_-_55866997 3.62 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr14_-_53258314 3.56 ENST00000216410.3
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr1_+_207226574 3.50 ENST00000367080.3
ENST00000367079.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr10_-_977564 3.47 ENST00000406525.2
La ribonucleoprotein domain family, member 4B
chr1_+_62439037 3.47 ENST00000545929.1
InaD-like (Drosophila)
chr17_+_72772621 3.43 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
transmembrane protein 104
chr17_-_79818354 3.37 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
prolyl 4-hydroxylase, beta polypeptide
chr6_+_26402465 3.30 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
butyrophilin, subfamily 3, member A1
chr14_+_22337014 3.29 ENST00000390436.2
T cell receptor alpha variable 13-1
chr19_-_10121144 3.26 ENST00000264828.3
collagen, type V, alpha 3
chrX_+_67913471 3.24 ENST00000374597.3
StAR-related lipid transfer (START) domain containing 8
chr11_+_117947782 3.15 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
transmembrane protease, serine 4
chr9_-_99540328 3.13 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
zinc finger protein 510
chr6_+_127587755 3.12 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr4_+_83821835 3.10 ENST00000302236.5
THAP domain containing 9
chrX_-_48271344 3.06 ENST00000376884.2
ENST00000396928.1
synovial sarcoma, X breakpoint 4B
chr7_+_99425633 3.05 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
cytochrome P450, family 3, subfamily A, polypeptide 43
chr6_+_26402517 3.05 ENST00000414912.2
butyrophilin, subfamily 3, member A1
chr19_+_2867325 3.02 ENST00000307635.2
ENST00000586426.1
zinc finger protein 556
chr5_+_176853702 2.99 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
G protein-coupled receptor kinase 6
chrX_+_100353153 2.96 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
centromere protein I
chr7_-_150020578 2.96 ENST00000478393.1
ARP3 actin-related protein 3 homolog C (yeast)
chr7_+_100209725 2.95 ENST00000223054.4
motile sperm domain containing 3
chr7_+_150020329 2.94 ENST00000323078.7
leucine rich repeat containing 61
chr4_+_155484155 2.90 ENST00000509493.1
fibrinogen beta chain
chr12_-_22063787 2.90 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_1259989 2.89 ENST00000540437.1
cleavage and polyadenylation specific factor 3-like
chr6_+_137143694 2.88 ENST00000367756.4
ENST00000541292.1
ENST00000318471.4
peroxisomal biogenesis factor 7
chr7_+_5919458 2.87 ENST00000416608.1
oncomodulin
chr19_+_41770269 2.86 ENST00000378215.4
heterogeneous nuclear ribonucleoprotein U-like 1
chr6_+_129204337 2.86 ENST00000421865.2
laminin, alpha 2
chr6_+_27100811 2.84 ENST00000359193.2
histone cluster 1, H2ag
chr22_-_22090064 2.83 ENST00000339468.3
yippee-like 1 (Drosophila)
chr11_-_327537 2.82 ENST00000602735.1
interferon induced transmembrane protein 3
chr19_+_4007644 2.77 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr1_-_207226313 2.74 ENST00000367084.1
YOD1 deubiquitinase
chr2_+_99797542 2.71 ENST00000338148.3
ENST00000512183.2
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chr11_+_122753391 2.68 ENST00000307257.6
ENST00000227349.2
chromosome 11 open reading frame 63
chr8_+_105235572 2.66 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr11_+_92085262 2.65 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr14_-_24711470 2.64 ENST00000559969.1
TERF1 (TRF1)-interacting nuclear factor 2
chr10_+_64133934 2.61 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
zinc finger protein 365
chr1_-_12908578 2.59 ENST00000317869.6
heterogeneous nuclear ribonucleoprotein C-like 1
chr5_+_176853669 2.58 ENST00000355472.5
G protein-coupled receptor kinase 6
chr7_+_100210133 2.56 ENST00000393950.2
ENST00000424091.2
motile sperm domain containing 3
chr7_+_150020363 2.54 ENST00000359623.4
ENST00000493307.1
leucine rich repeat containing 61
chrX_-_153363125 2.53 ENST00000407218.1
ENST00000453960.2
methyl CpG binding protein 2 (Rett syndrome)
chr1_-_48937821 2.52 ENST00000396199.3
spermatogenesis associated 6
chr3_+_152552685 2.49 ENST00000305097.3
purinergic receptor P2Y, G-protein coupled, 1
chr4_-_141348789 2.47 ENST00000414773.1
calmegin
chr6_+_31553978 2.46 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr1_+_12079517 2.44 ENST00000235332.4
ENST00000436478.2
migration and invasion inhibitory protein
chr6_+_160542870 2.43 ENST00000324965.4
ENST00000457470.2
solute carrier family 22 (organic cation transporter), member 1
chr19_-_3772209 2.43 ENST00000555978.1
ENST00000555633.1
retina and anterior neural fold homeobox 2
chrX_-_153363188 2.41 ENST00000303391.6
methyl CpG binding protein 2 (Rett syndrome)
chr20_+_54967409 2.40 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr2_+_79412357 2.40 ENST00000466387.1
catenin (cadherin-associated protein), alpha 2
chrX_+_138612889 2.34 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr11_+_117947724 2.33 ENST00000534111.1
transmembrane protease, serine 4
chr1_-_47407111 2.32 ENST00000371904.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chr11_-_32457075 2.31 ENST00000448076.3
Wilms tumor 1
chr17_+_72581057 2.30 ENST00000392620.1
chromosome 17 open reading frame 77
chr17_+_80416050 2.28 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
nuclear prelamin A recognition factor
chr15_-_26874230 2.28 ENST00000400188.3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr16_+_31271274 2.28 ENST00000287497.8
ENST00000544665.3
integrin, alpha M (complement component 3 receptor 3 subunit)
chr15_-_77712477 2.27 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chr19_+_12902289 2.26 ENST00000302754.4
jun B proto-oncogene
chr5_+_81575281 2.26 ENST00000380167.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr3_-_167191814 2.23 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr4_-_100212132 2.22 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chrX_+_48242863 2.22 ENST00000376886.2
ENST00000375517.3
synovial sarcoma, X breakpoint 4
chrX_+_134975753 2.21 ENST00000535938.1
sarcoma antigen 1
chr10_-_134756030 2.20 ENST00000368586.5
ENST00000368582.2
tetratricopeptide repeat domain 40
chrX_+_134975858 2.20 ENST00000537770.1
sarcoma antigen 1
chr12_-_118796910 2.17 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr7_+_100209979 2.14 ENST00000493970.1
ENST00000379527.2
motile sperm domain containing 3
chr2_+_87565634 2.13 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr6_-_27100529 2.13 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
histone cluster 1, H2bj
chr3_-_61237050 2.13 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
fragile histidine triad
chr19_+_48972459 2.10 ENST00000427476.1
cytohesin 2
chr11_-_128894053 2.10 ENST00000392657.3
Rho GTPase activating protein 32

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX7_NOBOX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 24.3 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
4.1 12.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
3.5 17.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
2.7 8.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
2.5 10.0 GO:0072166 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
2.3 16.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
2.3 6.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
2.0 8.1 GO:0061743 motor learning(GO:0061743)
1.9 22.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.8 23.4 GO:0070327 thyroid hormone transport(GO:0070327)
1.8 5.3 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.7 10.4 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
1.6 4.9 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
1.6 8.0 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
1.5 4.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.4 4.1 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.3 3.8 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.0 24.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
1.0 6.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.0 1.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
1.0 3.9 GO:0009822 alkaloid catabolic process(GO:0009822)
1.0 2.9 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.9 12.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.9 2.7 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.9 3.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.9 2.6 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.8 2.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.8 6.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.8 10.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.8 6.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.8 6.2 GO:0070544 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.8 10.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.7 4.4 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.7 3.6 GO:0006041 glucosamine metabolic process(GO:0006041)
0.7 5.0 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.7 11.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.7 2.1 GO:1903487 regulation of lactation(GO:1903487)
0.7 2.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.7 2.7 GO:0032053 ciliary basal body organization(GO:0032053)
0.6 4.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.6 6.2 GO:0015889 cobalamin transport(GO:0015889)
0.6 1.8 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.6 4.3 GO:0048241 epinephrine transport(GO:0048241)
0.6 2.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.6 3.5 GO:0033133 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.6 6.4 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.6 2.3 GO:0003095 pressure natriuresis(GO:0003095)
0.6 5.8 GO:0040016 embryonic cleavage(GO:0040016)
0.5 4.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.5 11.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.5 1.0 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.5 4.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.5 12.1 GO:0001502 cartilage condensation(GO:0001502)
0.5 1.9 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.5 5.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 4.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 3.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.4 9.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.4 2.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.4 0.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.4 1.6 GO:0002933 lipid hydroxylation(GO:0002933)
0.4 2.0 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.4 2.6 GO:0046836 glycolipid transport(GO:0046836)
0.4 1.5 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.4 3.6 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.4 1.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.3 7.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 6.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 1.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 2.9 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.3 0.9 GO:0060369 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3 2.4 GO:1902750 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.3 1.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 1.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.3 1.2 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.3 2.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.3 2.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.3 1.1 GO:0032218 riboflavin transport(GO:0032218)
0.3 3.1 GO:0015074 DNA integration(GO:0015074)
0.3 1.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.3 1.6 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.3 3.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 3.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 13.8 GO:0006458 'de novo' protein folding(GO:0006458)
0.2 0.7 GO:0042109 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 1.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 3.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 0.9 GO:0035425 autocrine signaling(GO:0035425)
0.2 1.1 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.2 4.9 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 38.5 GO:0002377 immunoglobulin production(GO:0002377)
0.2 3.9 GO:0042246 tissue regeneration(GO:0042246)
0.2 0.9 GO:0097527 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356) necroptotic signaling pathway(GO:0097527)
0.2 2.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 1.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 3.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 1.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 3.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 2.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 1.0 GO:0050955 thermoception(GO:0050955)
0.2 0.8 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2 4.0 GO:0030220 platelet formation(GO:0030220)
0.2 2.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 1.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.2 1.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 1.7 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 1.7 GO:0006069 ethanol oxidation(GO:0006069)
0.2 11.7 GO:0006611 protein export from nucleus(GO:0006611)
0.2 1.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 2.0 GO:0060539 diaphragm development(GO:0060539)
0.2 2.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 3.9 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 4.3 GO:0044458 motile cilium assembly(GO:0044458)
0.2 3.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.7 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 4.3 GO:0071711 basement membrane organization(GO:0071711)
0.1 1.9 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 5.8 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 1.7 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 2.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 7.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 2.3 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.1 1.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.9 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 2.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.2 GO:0072178 negative regulation of synapse assembly(GO:0051964) nephric duct morphogenesis(GO:0072178)
0.1 0.3 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 1.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 8.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:0036343 negative regulation of extracellular matrix disassembly(GO:0010716) psychomotor behavior(GO:0036343)
0.1 2.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 1.1 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 0.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 2.9 GO:0010107 potassium ion import(GO:0010107)
0.1 1.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 3.9 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.5 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.6 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.1 1.8 GO:0044804 nucleophagy(GO:0044804)
0.1 2.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.7 GO:0006552 leucine catabolic process(GO:0006552)
0.1 3.8 GO:0009790 embryo development(GO:0009790)
0.1 3.8 GO:0016266 O-glycan processing(GO:0016266)
0.1 26.9 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 1.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.7 GO:0045730 respiratory burst(GO:0045730)
0.1 8.3 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.0 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 2.1 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 1.7 GO:0030728 ovulation(GO:0030728)
0.1 4.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.4 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 4.9 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 1.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 1.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 3.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.4 GO:0009642 response to light intensity(GO:0009642)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.8 GO:0006067 ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.1 0.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 1.5 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 1.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.6 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 26.1 GO:0045596 negative regulation of cell differentiation(GO:0045596)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 6.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 6.0 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.9 GO:0007566 embryo implantation(GO:0007566)
0.0 1.8 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 5.9 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.6 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 2.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.4 GO:0010370 perinucleolar chromocenter(GO:0010370)
1.7 10.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.6 22.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.4 8.1 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.1 3.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.1 3.3 GO:0005588 collagen type V trimer(GO:0005588)
1.1 4.3 GO:0097224 sperm connecting piece(GO:0097224)
1.0 4.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.0 2.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.8 6.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.8 7.1 GO:0005579 membrane attack complex(GO:0005579)
0.7 2.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.6 2.6 GO:1990357 terminal web(GO:1990357)
0.6 1.9 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.6 8.0 GO:0043083 synaptic cleft(GO:0043083)
0.6 1.7 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.5 17.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 3.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.5 2.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.4 5.2 GO:0043203 axon hillock(GO:0043203)
0.4 4.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 3.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 9.9 GO:0032982 myosin filament(GO:0032982)
0.3 2.0 GO:1990130 Iml1 complex(GO:1990130)
0.3 5.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 4.3 GO:0005577 fibrinogen complex(GO:0005577)
0.3 3.5 GO:0042788 polysomal ribosome(GO:0042788)
0.3 6.9 GO:0000242 pericentriolar material(GO:0000242)
0.3 16.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.3 7.5 GO:0005605 basal lamina(GO:0005605)
0.3 7.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.3 2.3 GO:0035976 AP1 complex(GO:0035976)
0.3 2.0 GO:1990635 proximal dendrite(GO:1990635)
0.3 2.3 GO:0005638 lamin filament(GO:0005638)
0.3 2.0 GO:0032010 phagolysosome(GO:0032010)
0.2 1.5 GO:1990812 growth cone filopodium(GO:1990812)
0.2 4.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 6.3 GO:0030673 axolemma(GO:0030673)
0.2 1.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 3.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 2.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 2.0 GO:0036038 MKS complex(GO:0036038)
0.2 5.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.9 GO:0036021 endolysosome lumen(GO:0036021)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.5 GO:0030478 actin cap(GO:0030478)
0.1 1.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 4.9 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 19.6 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 4.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 8.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 3.9 GO:0001533 cornified envelope(GO:0001533)
0.1 2.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.7 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 2.9 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.1 10.8 GO:0072562 blood microparticle(GO:0072562)
0.1 18.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 23.5 GO:0010008 endosome membrane(GO:0010008)
0.0 0.6 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.3 GO:0031904 endosome lumen(GO:0031904)
0.0 4.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 29.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 3.8 GO:0005814 centriole(GO:0005814)
0.0 50.2 GO:0005615 extracellular space(GO:0005615)
0.0 1.3 GO:0005770 late endosome(GO:0005770)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 6.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0001726 ruffle(GO:0001726)
0.0 4.3 GO:0045177 apical part of cell(GO:0045177)
0.0 2.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0043235 receptor complex(GO:0043235)
0.0 1.4 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0000178 exosome (RNase complex)(GO:0000178)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
4.1 16.2 GO:0019770 IgG receptor activity(GO:0019770)
3.4 10.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
2.4 14.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
2.4 23.5 GO:0070324 thyroid hormone binding(GO:0070324)
2.0 10.0 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
1.9 5.6 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.8 5.4 GO:0032767 copper-dependent protein binding(GO:0032767)
1.5 4.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.4 10.1 GO:0008142 oxysterol binding(GO:0008142)
1.3 10.7 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 4.3 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.0 8.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.0 24.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.9 2.7 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.9 12.7 GO:0031432 titin binding(GO:0031432)
0.9 6.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 6.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.8 3.1 GO:0004803 transposase activity(GO:0004803)
0.7 3.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 3.6 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.7 4.9 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.7 3.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.7 4.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.6 2.5 GO:0031685 adenosine receptor binding(GO:0031685)
0.6 1.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.6 1.8 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.6 3.5 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.6 2.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.6 6.2 GO:0031419 cobalamin binding(GO:0031419)
0.6 2.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 11.5 GO:0035497 cAMP response element binding(GO:0035497)
0.5 2.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.5 4.1 GO:1990405 protein antigen binding(GO:1990405)
0.5 8.5 GO:0070330 aromatase activity(GO:0070330)
0.5 6.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 1.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 1.3 GO:0004802 transketolase activity(GO:0004802)
0.4 4.3 GO:0032027 myosin light chain binding(GO:0032027)
0.4 4.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 2.9 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.4 5.3 GO:0015643 toxic substance binding(GO:0015643)
0.4 1.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 5.0 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 3.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 23.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3 1.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.3 1.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.3 1.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 5.0 GO:0043495 protein anchor(GO:0043495)
0.2 1.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 1.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 2.6 GO:0039706 co-receptor binding(GO:0039706)
0.2 2.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.2 0.9 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 2.3 GO:0001851 complement component C3b binding(GO:0001851)
0.2 1.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 6.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 47.6 GO:0003823 antigen binding(GO:0003823)
0.2 4.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 10.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 2.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 5.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 21.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 1.0 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2 1.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 4.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 15.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 2.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.0 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 1.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 2.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 3.8 GO:0071949 FAD binding(GO:0071949)
0.1 7.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 2.3 GO:0005521 lamin binding(GO:0005521)
0.1 1.2 GO:0016918 retinal binding(GO:0016918)
0.1 0.4 GO:0008422 beta-glucuronidase activity(GO:0004566) beta-glucosidase activity(GO:0008422)
0.1 38.1 GO:0005096 GTPase activator activity(GO:0005096)
0.1 8.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 5.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.6 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.1 4.3 GO:0005518 collagen binding(GO:0005518)
0.1 2.0 GO:0070402 NADPH binding(GO:0070402)
0.1 1.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 4.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 2.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0016499 orexin receptor activity(GO:0016499)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 3.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 5.5 GO:0017022 myosin binding(GO:0017022)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 5.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 15.3 GO:0000287 magnesium ion binding(GO:0000287)
0.1 1.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 4.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.8 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0019001 guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.1 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 5.2 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 4.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 5.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 11.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 12.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 3.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 34.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 25.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 11.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 27.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 7.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 10.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 9.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 3.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 7.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 17.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 19.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 5.0 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 21.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID ARF 3PATHWAY Arf1 pathway
0.1 2.4 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 4.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.8 PID BMP PATHWAY BMP receptor signaling
0.0 3.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 3.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 4.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.0 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 2.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.9 10.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.8 22.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.7 19.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 7.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.6 10.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5 11.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 3.8 REACTOME OPSINS Genes involved in Opsins
0.3 5.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 26.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 2.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 3.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 7.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 6.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 4.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 12.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 6.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 28.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 7.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 3.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 5.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 5.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 4.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 4.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 6.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 4.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 2.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.9 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 2.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.1 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.1 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 4.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 3.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 6.7 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling