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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PGR

Z-value: 0.79

Motif logo

Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
ENSG00000082175.10 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg19_v2_chr11_-_100999775_100999801,
hg19_v2_chr11_-_101000445_101000465
0.127.8e-02Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_88450612 19.03 ENST00000418378.1
ENST00000282470.6
SPARC-like 1 (hevin)
chr3_-_114343768 9.39 ENST00000393785.2
zinc finger and BTB domain containing 20
chrX_+_38420623 7.70 ENST00000378482.2
tetraspanin 7
chr3_-_114343039 6.91 ENST00000481632.1
zinc finger and BTB domain containing 20
chr3_-_48057890 6.78 ENST00000434267.1
microtubule-associated protein 4
chr8_-_22089845 6.78 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr15_+_31619013 6.44 ENST00000307145.3
Kruppel-like factor 13
chr7_+_30960915 6.40 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr3_-_58563094 6.35 ENST00000464064.1
family with sequence similarity 107, member A
chr6_-_154831779 6.32 ENST00000607772.1
CNKSR family member 3
chr18_+_29171689 5.98 ENST00000237014.3
transthyretin
chr12_+_79258547 5.97 ENST00000457153.2
synaptotagmin I
chr7_-_37026108 5.80 ENST00000396045.3
engulfment and cell motility 1
chr11_-_66725837 5.50 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr6_-_32908765 5.39 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr3_-_114035026 5.16 ENST00000570269.1
RP11-553L6.5
chr19_-_36247910 5.07 ENST00000587965.1
ENST00000004982.3
heat shock protein, alpha-crystallin-related, B6
chr5_-_160279207 5.01 ENST00000327245.5
ATPase, class V, type 10B
chr17_-_26903900 4.92 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
aldolase C, fructose-bisphosphate
chr7_-_129845313 4.58 ENST00000397622.2
transmembrane protein 209
chr8_+_133931648 4.57 ENST00000519178.1
ENST00000542445.1
thyroglobulin
chr10_-_28571015 4.39 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr7_-_129845188 4.27 ENST00000462753.1
ENST00000471077.1
ENST00000473456.1
ENST00000336804.8
transmembrane protein 209
chr19_-_40440533 4.12 ENST00000221347.6
Fc fragment of IgG binding protein
chr19_-_14952689 3.88 ENST00000248058.1
olfactory receptor, family 7, subfamily A, member 10
chr13_+_32838801 3.86 ENST00000542859.1
furry homolog (Drosophila)
chr9_+_87285539 3.74 ENST00000359847.3
neurotrophic tyrosine kinase, receptor, type 2
chr6_-_136788001 3.73 ENST00000544465.1
microtubule-associated protein 7
chr19_+_30863271 3.64 ENST00000355537.3
zinc finger protein 536
chr15_+_31658349 3.60 ENST00000558844.1
Kruppel-like factor 13
chr12_-_11422630 3.58 ENST00000381842.3
ENST00000538488.1
proline-rich protein BstNI subfamily 3
chr19_+_19431490 3.56 ENST00000392313.6
ENST00000262815.8
ENST00000609122.1
MAU2 sister chromatid cohesion factor
chr4_-_87028478 3.55 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chrX_+_46940254 3.43 ENST00000336169.3
regucalcin
chr11_+_64851729 3.42 ENST00000526791.1
ENST00000526945.1
zinc finger protein-like 1
chr2_+_99797542 3.39 ENST00000338148.3
ENST00000512183.2
mitochondrial ribosomal protein L30
chromosome 2 open reading frame 15
chrX_-_78622805 3.39 ENST00000373298.2
integral membrane protein 2A
chr15_-_42783303 3.36 ENST00000565380.1
ENST00000564754.1
zinc finger protein 106
chr3_+_111260954 3.30 ENST00000283285.5
CD96 molecule
chr3_+_187871060 3.26 ENST00000448637.1
LIM domain containing preferred translocation partner in lipoma
chr1_+_155829286 3.24 ENST00000368324.4
synaptotagmin XI
chr13_+_102104952 3.23 ENST00000376180.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_111260856 3.18 ENST00000352690.4
CD96 molecule
chr2_+_60983361 3.17 ENST00000238714.3
poly(A) polymerase gamma
chrX_+_23352133 3.08 ENST00000379361.4
patched domain containing 1
chr14_+_24641062 3.06 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8 meiotic recombination protein
chr5_+_67584174 3.00 ENST00000320694.8
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_+_10530155 3.00 ENST00000521818.1
chromosome 8 open reading frame 74
chr22_+_41253080 2.95 ENST00000541156.1
ENST00000414396.1
ENST00000357137.4
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr2_-_175711133 2.95 ENST00000409597.1
ENST00000413882.1
chimerin 1
chr8_-_26371608 2.94 ENST00000522362.2
paraneoplastic Ma antigen 2
chr19_+_10531150 2.92 ENST00000352831.6
phosphodiesterase 4A, cAMP-specific
chr12_+_125478241 2.91 ENST00000341446.8
BRI3 binding protein
chr20_+_23016057 2.89 ENST00000255008.3
somatostatin receptor 4
chr6_+_27107053 2.87 ENST00000354348.2
histone cluster 1, H4i
chr18_+_580367 2.87 ENST00000327228.3
centrin, EF-hand protein, 1
chr19_-_19144243 2.84 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr7_+_73442422 2.84 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
elastin
chrX_-_130037198 2.78 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ecto-NOX disulfide-thiol exchanger 2
chr6_+_72926145 2.78 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr15_-_88799661 2.73 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr1_+_150229554 2.72 ENST00000369111.4
carbonic anhydrase XIV
chr5_+_102201687 2.70 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr4_+_128802016 2.60 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
polo-like kinase 4
chr1_+_111770232 2.60 ENST00000369744.2
chitinase 3-like 2
chr13_+_49822041 2.60 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
cytidine and dCMP deaminase domain containing 1
chr1_+_111770278 2.55 ENST00000369748.4
chitinase 3-like 2
chr5_-_146435694 2.54 ENST00000356826.3
protein phosphatase 2, regulatory subunit B, beta
chr2_+_234602305 2.51 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr12_-_71551652 2.51 ENST00000546561.1
tetraspanin 8
chr9_-_113761720 2.46 ENST00000541779.1
ENST00000374430.2
lysophosphatidic acid receptor 1
chr1_-_201390846 2.45 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
troponin I type 1 (skeletal, slow)
chr2_+_173686303 2.45 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr14_-_106692191 2.45 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr15_-_88799384 2.43 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
neurotrophic tyrosine kinase, receptor, type 3
chr12_-_11422739 2.41 ENST00000279573.7
proline-rich protein BstNI subfamily 3
chr4_-_71532339 2.41 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_179672142 2.38 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr5_-_131347501 2.37 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr3_+_137906154 2.36 ENST00000466749.1
ENST00000358441.2
ENST00000489213.1
armadillo repeat containing 8
chr8_-_87755878 2.35 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chrX_+_57618269 2.33 ENST00000374888.1
zinc finger, X-linked, duplicated B
chr16_-_3306587 2.33 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
Mediterranean fever
chr5_-_115872142 2.27 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_-_146435501 2.27 ENST00000336640.6
protein phosphatase 2, regulatory subunit B, beta
chr5_+_140261703 2.26 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr6_-_46922659 2.20 ENST00000265417.7
G protein-coupled receptor 116
chr7_+_128116783 2.19 ENST00000262432.8
ENST00000480046.1
methyltransferase like 2B
chr3_+_46412345 2.17 ENST00000292303.4
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr12_-_49110613 2.16 ENST00000261900.3
cyclin T1
chr5_-_146435572 2.16 ENST00000394414.1
protein phosphatase 2, regulatory subunit B, beta
chr3_-_149470229 2.15 ENST00000473414.1
COMM domain containing 2
chr19_+_41119323 2.11 ENST00000599724.1
ENST00000597071.1
ENST00000243562.9
latent transforming growth factor beta binding protein 4
chr17_-_15168624 2.10 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
peripheral myelin protein 22
chr3_-_49722523 2.10 ENST00000448220.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr15_-_58306295 2.09 ENST00000559517.1
aldehyde dehydrogenase 1 family, member A2
chr11_+_123396528 2.06 ENST00000322282.7
ENST00000529750.1
GRAM domain containing 1B
chr6_+_39760129 2.06 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr7_-_135433460 2.05 ENST00000415751.1
family with sequence similarity 180, member A
chr1_+_192778161 2.04 ENST00000235382.5
regulator of G-protein signaling 2, 24kDa
chr2_-_73869508 2.04 ENST00000272425.3
N-acetyltransferase 8 (GCN5-related, putative)
chr22_+_40297105 2.04 ENST00000540310.1
GRB2-related adaptor protein 2
chr6_-_32908792 2.03 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chrX_-_102348017 1.99 ENST00000425644.1
ENST00000395065.3
ENST00000425463.2
nuclear RNA export factor 3
chr22_-_31688431 1.97 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr9_-_37034028 1.94 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
paired box 5
chr2_-_89266286 1.93 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr19_+_35773242 1.89 ENST00000222304.3
hepcidin antimicrobial peptide
chr19_+_41768561 1.87 ENST00000599719.1
ENST00000601309.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr11_+_64851666 1.86 ENST00000525509.1
ENST00000294258.3
ENST00000526334.1
zinc finger protein-like 1
chr7_+_73442457 1.86 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
elastin
chr19_+_44488330 1.85 ENST00000591532.1
ENST00000407951.2
ENST00000270014.2
ENST00000590615.1
ENST00000586454.1
zinc finger protein 155
chrX_-_49965663 1.85 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
A kinase (PRKA) anchor protein 4
chr1_-_32210275 1.84 ENST00000440175.2
brain-specific angiogenesis inhibitor 2
chr5_+_156607829 1.79 ENST00000422843.3
IL2-inducible T-cell kinase
chr17_-_46608272 1.74 ENST00000577092.1
ENST00000239174.6
homeobox B1
chr21_+_34398153 1.74 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
oligodendrocyte lineage transcription factor 2
chr19_-_6333614 1.73 ENST00000301452.4
alkaline ceramidase 1
chr15_-_45406385 1.72 ENST00000389039.6
dual oxidase 2
chr1_+_43803475 1.72 ENST00000372470.3
ENST00000413998.2
myeloproliferative leukemia virus oncogene
chr16_+_85942594 1.72 ENST00000566369.1
interferon regulatory factor 8
chr6_+_108487245 1.71 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1
chr17_-_3301704 1.71 ENST00000322608.2
olfactory receptor, family 1, subfamily E, member 1
chr5_-_131347583 1.70 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
acyl-CoA synthetase long-chain family member 6
chr9_+_82188077 1.69 ENST00000425506.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr22_-_30162924 1.68 ENST00000344318.3
ENST00000397781.3
zinc finger, matrin-type 5
chrX_+_135570046 1.67 ENST00000370648.3
bombesin-like receptor 3
chr2_-_219537134 1.65 ENST00000295704.2
ring finger protein 25
chrX_-_112084043 1.63 ENST00000304758.1
angiomotin
chr7_-_5821314 1.63 ENST00000425013.2
ENST00000389902.3
ring finger protein 216
chr22_+_40297079 1.61 ENST00000344138.4
ENST00000543252.1
GRB2-related adaptor protein 2
chr2_-_208994548 1.60 ENST00000282141.3
crystallin, gamma C
chr1_+_209859510 1.59 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr2_+_48796120 1.56 ENST00000394754.1
STON1-GTF2A1L readthrough
chr18_+_43304092 1.54 ENST00000321925.4
ENST00000587601.1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr7_+_73442487 1.52 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
elastin
chr14_-_107219365 1.51 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr22_-_31688381 1.51 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr16_-_20338748 1.42 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
glycoprotein 2 (zymogen granule membrane)
chr3_+_52454971 1.41 ENST00000465863.1
PHD finger protein 7
chr7_+_73442102 1.39 ENST00000445912.1
ENST00000252034.7
elastin
chr1_-_233431458 1.38 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr5_+_140797296 1.37 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr20_+_30063067 1.37 ENST00000201979.2
RAS (RAD and GEM)-like GTP-binding 1
chr17_-_3337135 1.36 ENST00000248384.1
olfactory receptor, family 1, subfamily E, member 2
chr15_-_43877062 1.35 ENST00000381885.1
ENST00000396923.3
diphosphoinositol pentakisphosphate kinase 1
chr10_-_104178857 1.35 ENST00000020673.5
pleckstrin and Sec7 domain containing
chr6_-_53013620 1.33 ENST00000259803.7
glial cells missing homolog 1 (Drosophila)
chr19_+_16771936 1.32 ENST00000187762.2
ENST00000599479.1
transmembrane protein 38A
chr9_+_131703757 1.32 ENST00000482796.1
RP11-101E3.5
chr20_+_52105495 1.31 ENST00000439873.2
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chrX_-_100641155 1.29 ENST00000372880.1
ENST00000308731.7
Bruton agammaglobulinemia tyrosine kinase
chr3_-_52001448 1.29 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr10_-_72142345 1.25 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
leucine rich repeat containing 20
chr5_-_148442584 1.25 ENST00000394358.2
ENST00000512049.1
SH3 domain and tetratricopeptide repeats 2
chr18_+_6729725 1.24 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
Rho GTPase activating protein 28
chr2_+_73144604 1.24 ENST00000258106.6
empty spiracles homeobox 1
chr17_-_26694979 1.24 ENST00000438614.1
vitronectin
chr1_+_155146318 1.23 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
tripartite motif containing 46
chr17_-_26879567 1.23 ENST00000581945.1
ENST00000444148.1
ENST00000301032.4
ENST00000335765.4
unc-119 homolog (C. elegans)
chr18_-_44336998 1.21 ENST00000315087.7
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr3_+_29323043 1.21 ENST00000452462.1
ENST00000456853.1
RNA binding motif, single stranded interacting protein 3
chrX_-_45060135 1.21 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr4_-_90759440 1.19 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr3_+_137906353 1.18 ENST00000461822.1
ENST00000485396.1
ENST00000471453.1
ENST00000470821.1
ENST00000471709.1
ENST00000538260.1
ENST00000393058.3
ENST00000463485.1
armadillo repeat containing 8
chr1_+_197237352 1.15 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chr17_-_46691990 1.13 ENST00000576562.1
homeobox B8
chr17_-_15522826 1.12 ENST00000395906.3
CMT1A duplicated region transcript 1
chrX_+_69672136 1.12 ENST00000374355.3
discs, large homolog 3 (Drosophila)
chr2_-_183387430 1.09 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr2_+_234601512 1.09 ENST00000305139.6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr2_+_27237615 1.08 ENST00000458529.1
ENST00000402218.1
microtubule-associated protein, RP/EB family, member 3
chr12_-_88974236 1.06 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KIT ligand
chr5_+_66124590 1.05 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
microtubule associated serine/threonine kinase family member 4
chr17_-_4464081 1.05 ENST00000574154.1
gamma-glutamyltransferase 6
chr5_-_131347306 1.04 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
acyl-CoA synthetase long-chain family member 6
chr18_+_6729698 1.04 ENST00000383472.4
Rho GTPase activating protein 28
chr17_+_25958174 1.03 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr14_-_23877474 1.03 ENST00000405093.3
myosin, heavy chain 6, cardiac muscle, alpha
chr3_+_149530836 1.01 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
ring finger protein 13
chrX_+_15525426 0.99 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr5_+_133861339 0.99 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
jade family PHD finger 2
chrX_-_101718085 0.98 ENST00000372750.1
ENST00000372752.1
nuclear RNA export factor 2B
chrX_+_16964985 0.96 ENST00000303843.7
RALBP1 associated Eps domain containing 2
chr19_-_51529849 0.95 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
kallikrein-related peptidase 11
chr19_-_54726850 0.95 ENST00000245620.9
ENST00000346401.6
ENST00000424807.1
ENST00000445347.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr2_-_183387283 0.93 ENST00000435564.1
phosphodiesterase 1A, calmodulin-dependent
chr2_+_64681219 0.92 ENST00000238875.5
lectin, galactoside-binding-like
chr17_+_34136459 0.92 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr7_+_105603657 0.90 ENST00000542731.1
ENST00000343407.5
cadherin-related family member 3
chr8_+_23104130 0.90 ENST00000313219.7
ENST00000519984.1
charged multivesicular body protein 7
chr1_+_16010779 0.90 ENST00000375799.3
ENST00000375793.2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr4_+_177241094 0.90 ENST00000503362.1
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr1_-_145039949 0.87 ENST00000313382.9
phosphodiesterase 4D interacting protein
chr14_-_23876801 0.86 ENST00000356287.3
myosin, heavy chain 6, cardiac muscle, alpha
chr13_-_99667960 0.83 ENST00000448493.2
dedicator of cytokinesis 9
chr2_+_27193480 0.81 ENST00000233121.2
ENST00000405074.3
microtubule-associated protein, RP/EB family, member 3
chr1_+_158815588 0.81 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr21_-_34186006 0.81 ENST00000490358.1
chromosome 21 open reading frame 62
chr7_+_143657027 0.81 ENST00000392899.1
olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 3.6 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
2.8 8.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
2.2 6.5 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
2.1 6.4 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
2.0 6.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.8 5.5 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.7 5.2 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
1.3 5.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
1.2 3.5 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
1.1 3.4 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.1 6.8 GO:0051012 microtubule sliding(GO:0051012)
1.0 10.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.9 3.6 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.9 1.7 GO:0021571 rhombomere 5 development(GO:0021571)
0.9 1.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.8 3.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.8 2.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.8 2.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.8 2.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.8 2.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.7 3.7 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.6 1.9 GO:1990641 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.6 1.9 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.6 4.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.6 2.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.6 1.7 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.6 2.9 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.6 1.7 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.5 1.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.5 2.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.5 4.6 GO:0015705 iodide transport(GO:0015705)
0.5 3.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.5 5.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.5 6.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 1.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.4 3.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 1.7 GO:0042335 cuticle development(GO:0042335)
0.4 1.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.4 0.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.3 1.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 2.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 1.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 16.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 2.0 GO:0010519 negative regulation of phospholipase activity(GO:0010519) regulation of adrenergic receptor signaling pathway(GO:0071877)
0.3 2.8 GO:0001865 NK T cell differentiation(GO:0001865)
0.3 3.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 4.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 3.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 1.2 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.2 1.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 2.1 GO:0035799 ureter maturation(GO:0035799)
0.2 3.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.2 3.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 2.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 5.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 1.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 3.1 GO:0021794 thalamus development(GO:0021794)
0.2 0.6 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.2 3.0 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.2 0.7 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 4.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 3.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 0.6 GO:0071812 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.2 1.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 0.9 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.2 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 0.6 GO:0070253 somatostatin secretion(GO:0070253)
0.2 3.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.2 2.8 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 7.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 0.6 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.7 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 4.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 5.1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 5.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.1 GO:0032060 bleb assembly(GO:0032060)
0.1 1.9 GO:0021670 lateral ventricle development(GO:0021670)
0.1 1.2 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.2 GO:0099612 protein localization to axon(GO:0099612)
0.1 4.0 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 6.9 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 1.7 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 2.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.6 GO:0035624 receptor transactivation(GO:0035624)
0.1 0.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 1.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 1.7 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 1.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 1.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.6 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 7.6 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 3.0 GO:0003094 glomerular filtration(GO:0003094)
0.1 6.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 2.6 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.4 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.7 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 5.2 GO:0001558 regulation of cell growth(GO:0001558)
0.1 2.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 2.1 GO:0030252 growth hormone secretion(GO:0030252)
0.1 1.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.6 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.4 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.8 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1 0.9 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 1.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 1.9 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 4.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 1.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 2.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 1.2 GO:0097503 sialylation(GO:0097503)
0.0 2.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 2.5 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.7 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.8 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.0 3.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.8 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 1.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:0030238 male sex determination(GO:0030238)
0.0 1.1 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 1.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 16.5 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 1.0 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 4.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 3.0 GO:0016032 viral process(GO:0016032)
0.0 1.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105) peptidyl-serine modification(GO:0018209)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 4.7 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 1.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 2.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.8 GO:0007050 cell cycle arrest(GO:0007050)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.2 6.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.0 3.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.9 2.6 GO:0098536 deuterosome(GO:0098536)
0.8 7.6 GO:0071953 elastic fiber(GO:0071953)
0.8 3.0 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.6 3.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.5 2.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.5 5.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 1.8 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 4.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 7.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.9 GO:0045179 apical cortex(GO:0045179)
0.2 1.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.2 2.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 1.2 GO:1990769 proximal neuron projection(GO:1990769)
0.2 7.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.1 3.2 GO:0005861 troponin complex(GO:0005861)
0.1 0.6 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.9 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.7 GO:0005927 muscle tendon junction(GO:0005927)
0.1 4.3 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 8.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 3.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 4.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 3.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 5.6 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 2.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.1 GO:0043218 compact myelin(GO:0043218)
0.1 1.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.8 GO:0051233 spindle midzone(GO:0051233)
0.1 0.5 GO:0032039 integrator complex(GO:0032039)
0.1 5.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 9.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.8 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 11.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 4.2 GO:0043204 perikaryon(GO:0043204)
0.0 6.2 GO:0001726 ruffle(GO:0001726)
0.0 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 3.9 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 2.5 GO:0043197 dendritic spine(GO:0043197)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 5.3 GO:0043235 receptor complex(GO:0043235)
0.0 4.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.3 GO:0055037 recycling endosome(GO:0055037)
0.0 3.0 GO:0030424 axon(GO:0030424)
0.0 1.9 GO:0001650 fibrillar center(GO:0001650)
0.0 1.4 GO:0060076 excitatory synapse(GO:0060076)
0.0 4.8 GO:0016604 nuclear body(GO:0016604)
0.0 1.0 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.2 6.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.9 3.6 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.7 3.7 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.6 5.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.6 6.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.6 3.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 2.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.6 2.9 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.6 5.5 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.5 1.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 2.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 2.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.5 5.2 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.5 3.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 3.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 4.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 1.7 GO:0017040 ceramidase activity(GO:0017040)
0.4 2.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 3.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 1.5 GO:0015265 urea channel activity(GO:0015265)
0.4 3.0 GO:0043559 insulin binding(GO:0043559)
0.4 1.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.3 1.0 GO:0048030 disaccharide binding(GO:0048030)
0.3 1.9 GO:0017018 myosin phosphatase activity(GO:0017018)
0.3 21.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 5.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 2.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 1.6 GO:0043532 angiostatin binding(GO:0043532)
0.3 1.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 2.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 7.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 1.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 2.4 GO:0031433 telethonin binding(GO:0031433)
0.2 6.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.8 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 0.6 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.2 3.1 GO:0003682 chromatin binding(GO:0003682)
0.2 2.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 3.9 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.2 1.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 2.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 2.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 4.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 7.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 2.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 3.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.5 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 20.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.7 GO:0004630 phospholipase D activity(GO:0004630)
0.1 5.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 5.4 GO:0030552 cAMP binding(GO:0030552)
0.1 1.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 2.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 3.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 8.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 2.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 1.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 6.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.0 GO:0030145 manganese ion binding(GO:0030145)
0.1 8.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 1.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0030553 cGMP binding(GO:0030553)
0.0 1.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 3.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 1.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 3.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 4.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 6.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 2.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 6.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 4.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 8.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 28.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 5.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 3.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.5 6.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 2.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 5.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 2.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 10.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 7.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 4.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 3.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 6.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 5.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 2.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 10.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 5.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 3.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 5.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi