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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for PLAG1

Z-value: 1.09

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Transcription factors associated with PLAG1

Gene Symbol Gene ID Gene Info
PLAG1
ENSG00000181690.3 PLAG1 zinc finger

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PLAG1hg19_v2_chr8_-_57123815_571238670.304.9e-06Click!

Activity profile of PLAG1 motif

Sorted Z-values of PLAG1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_139874683 29.76 ENST00000444903.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr12_+_79258444 19.04 ENST00000261205.4
SYT1
synaptotagmin I
chr10_-_21786179 17.42 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr12_+_79258547 17.06 ENST00000457153.2
SYT1
synaptotagmin I
chr8_+_21912328 15.13 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
DMTN
dematin actin binding protein
chr12_+_57522258 14.02 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr7_+_72742162 13.50 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr7_-_158380371 12.16 ENST00000389418.4
ENST00000389416.4
PTPRN2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr7_+_72742178 11.60 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr15_+_74833518 11.60 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr11_-_2160180 11.54 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_-_111170526 11.33 ENST00000355430.4
COLCA1
colorectal cancer associated 1
chr3_+_32726774 11.33 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chrX_+_110339439 11.29 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chrX_+_51927919 10.97 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr11_-_6440283 10.70 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr6_-_33285505 10.32 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr5_+_161274940 10.28 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr19_+_40697514 10.20 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr7_-_158380465 10.17 ENST00000389413.3
ENST00000409483.1
PTPRN2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr18_-_51750948 9.69 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr6_-_150039249 9.29 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr15_+_29131103 9.21 ENST00000558402.1
ENST00000558330.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr14_-_93799360 9.14 ENST00000334746.5
ENST00000554565.1
ENST00000298896.3
BTBD7
BTB (POZ) domain containing 7
chrX_-_45060135 8.58 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr12_-_122018859 8.54 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B
lysine (K)-specific demethylase 2B
chr1_+_163038565 8.22 ENST00000421743.2
RGS4
regulator of G-protein signaling 4
chr20_-_18038521 7.95 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chr10_-_75571566 7.94 ENST00000299641.4
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr12_-_112819896 7.64 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECTD4
HECT domain containing E3 ubiquitin protein ligase 4
chr1_-_31845914 7.51 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr4_-_5890145 7.20 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr12_-_52715179 7.18 ENST00000293670.3
KRT83
keratin 83
chr14_+_57857262 7.17 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr11_-_45687128 7.14 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr11_-_73309228 7.12 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr5_+_161275320 7.02 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_22962948 6.84 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr12_+_107168342 6.77 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr10_-_75571341 6.72 ENST00000309979.6
NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr22_+_29469100 6.58 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr16_+_29674277 6.54 ENST00000395389.2
SPN
sialophorin
chrX_-_137793826 6.48 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr14_-_75079026 6.32 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr2_-_152955213 6.21 ENST00000427385.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_+_73106035 6.19 ENST00000581078.1
ENST00000582136.1
ENST00000245543.1
ARMC7
armadillo repeat containing 7
chr11_-_57282349 6.19 ENST00000528450.1
SLC43A1
solute carrier family 43 (amino acid system L transporter), member 1
chr20_+_18269121 6.17 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
ZNF133
zinc finger protein 133
chr11_+_46299199 5.99 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr6_-_31940065 5.84 ENST00000375349.3
ENST00000337523.5
DXO
decapping exoribonuclease
chr16_-_65155833 5.67 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chrY_+_22737604 5.54 ENST00000361365.2
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr10_-_99447024 5.41 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr17_-_4607335 5.37 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
PELP1
proline, glutamate and leucine rich protein 1
chr9_-_123476612 5.32 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr9_-_123476719 5.30 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr16_+_31128978 5.20 ENST00000448516.2
ENST00000219797.4
KAT8
K(lysine) acetyltransferase 8
chr2_-_30144432 5.17 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr9_-_135819987 4.91 ENST00000298552.3
ENST00000403810.1
TSC1
tuberous sclerosis 1
chr2_-_21266935 4.77 ENST00000233242.1
APOB
apolipoprotein B
chr16_-_29910853 4.74 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr1_-_110613276 4.71 ENST00000369792.4
ALX3
ALX homeobox 3
chr19_-_2702681 4.65 ENST00000382159.3
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chrX_-_78622805 4.63 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr14_+_79746249 4.59 ENST00000428277.2
NRXN3
neurexin 3
chr16_+_2198604 4.55 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr3_-_52001448 4.51 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr22_+_29469012 4.50 ENST00000400335.4
ENST00000400338.2
KREMEN1
kringle containing transmembrane protein 1
chr10_+_111767720 4.46 ENST00000356080.4
ENST00000277900.8
ADD3
adducin 3 (gamma)
chr1_-_20306909 4.46 ENST00000375111.3
ENST00000400520.3
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr2_-_86850949 4.28 ENST00000237455.4
RNF103
ring finger protein 103
chr4_+_55095264 4.28 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr14_+_79745746 4.26 ENST00000281127.7
NRXN3
neurexin 3
chr2_-_152955537 4.25 ENST00000201943.5
ENST00000539935.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr5_-_59189545 4.24 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_-_140115775 4.14 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chrX_-_71526999 4.10 ENST00000453707.2
ENST00000373619.3
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr14_+_79745682 4.01 ENST00000557594.1
NRXN3
neurexin 3
chr12_-_12419703 3.96 ENST00000543091.1
ENST00000261349.4
LRP6
low density lipoprotein receptor-related protein 6
chr17_+_48046538 3.88 ENST00000240306.3
DLX4
distal-less homeobox 4
chr2_-_178937478 3.85 ENST00000286063.6
PDE11A
phosphodiesterase 11A
chr11_-_64511789 3.84 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_1420006 3.76 ENST00000320345.6
ENST00000406424.4
INPP5K
inositol polyphosphate-5-phosphatase K
chr15_+_92397051 3.60 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr3_+_14989076 3.54 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr2_+_16080659 3.49 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr12_+_121163538 3.47 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr20_+_35169885 3.41 ENST00000279022.2
ENST00000346786.2
MYL9
myosin, light chain 9, regulatory
chr16_-_30134524 3.37 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3
mitogen-activated protein kinase 3
chr3_-_73673991 3.33 ENST00000308537.4
ENST00000263666.4
PDZRN3
PDZ domain containing ring finger 3
chr17_+_7284365 3.24 ENST00000311668.2
TNK1
tyrosine kinase, non-receptor, 1
chr12_-_108733078 3.22 ENST00000552995.1
ENST00000312143.7
ENST00000397688.2
ENST00000550402.1
CMKLR1
chemokine-like receptor 1
chr3_-_197024394 3.12 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr20_-_1974692 3.09 ENST00000217305.2
ENST00000539905.1
PDYN
prodynorphin
chr6_+_106534192 3.07 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr2_-_74618964 3.06 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr3_+_19988885 2.93 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr16_+_29984962 2.92 ENST00000308893.4
TAOK2
TAO kinase 2
chr22_+_19744226 2.68 ENST00000332710.4
ENST00000329705.7
ENST00000359500.3
TBX1
T-box 1
chr1_-_204654481 2.61 ENST00000367176.3
LRRN2
leucine rich repeat neuronal 2
chr11_+_66610883 2.47 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr3_+_124303539 2.44 ENST00000428018.2
KALRN
kalirin, RhoGEF kinase
chr13_+_53602894 2.34 ENST00000219022.2
OLFM4
olfactomedin 4
chr2_+_157292933 2.19 ENST00000540309.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr3_-_15374033 2.18 ENST00000253688.5
ENST00000383791.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr6_+_7727030 2.14 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr9_-_34662651 2.13 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr10_+_50817141 2.10 ENST00000339797.1
CHAT
choline O-acetyltransferase
chr1_+_2407754 1.99 ENST00000419816.2
ENST00000378486.3
ENST00000378488.3
ENST00000288766.5
PLCH2
phospholipase C, eta 2
chr16_-_29910365 1.92 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr9_-_136004782 1.90 ENST00000393157.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr2_-_233352531 1.74 ENST00000304546.1
ECEL1
endothelin converting enzyme-like 1
chr13_-_49107303 1.61 ENST00000344532.3
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr11_+_1940925 1.59 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3
troponin T type 3 (skeletal, fast)
chr17_-_50237374 1.52 ENST00000442502.2
CA10
carbonic anhydrase X
chr2_-_128399706 1.47 ENST00000426981.1
LIMS2
LIM and senescent cell antigen-like domains 2
chr19_+_45973120 1.46 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr10_+_102891048 1.32 ENST00000467928.2
TLX1
T-cell leukemia homeobox 1
chr1_-_201438282 1.28 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr1_-_115632035 1.27 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
TSPAN2
tetraspanin 2
chr1_-_92949505 1.25 ENST00000370332.1
GFI1
growth factor independent 1 transcription repressor
chr7_-_22233442 1.25 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr14_+_32546485 1.25 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr12_-_58131931 1.14 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_31939608 1.07 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr20_+_35201857 1.00 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr6_-_71012773 0.85 ENST00000370496.3
ENST00000357250.6
COL9A1
collagen, type IX, alpha 1
chr2_+_220306745 0.76 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr2_-_74619152 0.76 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr11_+_63997750 0.76 ENST00000321685.3
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr4_-_38666430 0.68 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr1_+_202431859 0.57 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr12_+_57998595 0.45 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
DTX3
deltex homolog 3 (Drosophila)
chr14_-_36989427 0.44 ENST00000354822.5
NKX2-1
NK2 homeobox 1
chr19_+_38924316 0.43 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1
ryanodine receptor 1 (skeletal)
chr7_+_73703728 0.41 ENST00000361545.5
ENST00000223398.6
CLIP2
CAP-GLY domain containing linker protein 2
chr4_-_155533787 0.32 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr1_-_27701307 0.32 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr19_-_18653781 0.24 ENST00000596558.2
ENST00000453489.2
FKBP8
FK506 binding protein 8, 38kDa
chr12_+_57998400 0.21 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr17_-_3819751 0.16 ENST00000225538.3
P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
chr16_-_18812746 0.11 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ARL6IP1
RP11-1035H13.3
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr14_-_106518922 0.10 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr3_+_19988566 0.07 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr14_-_25519317 0.06 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.0 36.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
4.7 14.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
3.6 10.7 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
3.1 25.1 GO:0034587 piRNA metabolic process(GO:0034587)
2.8 8.5 GO:0021678 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
2.5 15.1 GO:0070560 protein secretion by platelet(GO:0070560)
2.5 7.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
2.4 7.2 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
2.0 7.9 GO:0060214 endocardium formation(GO:0060214)
2.0 4.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
1.9 9.3 GO:0001826 inner cell mass cell differentiation(GO:0001826)
1.7 29.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.6 6.5 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
1.5 10.2 GO:0007256 activation of JNKK activity(GO:0007256)
1.4 4.3 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.3 6.5 GO:1990834 response to odorant(GO:1990834)
1.3 5.2 GO:0036269 swimming behavior(GO:0036269)
1.3 11.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.2 14.7 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
1.2 7.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.2 4.6 GO:0002317 plasma cell differentiation(GO:0002317)
1.0 4.9 GO:0051029 rRNA transport(GO:0051029)
0.9 3.8 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.9 2.7 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.9 17.3 GO:0071420 cellular response to histamine(GO:0071420)
0.8 12.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.7 4.1 GO:0071105 response to interleukin-11(GO:0071105)
0.7 4.8 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
0.7 3.4 GO:0000189 MAPK import into nucleus(GO:0000189)
0.7 6.0 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.6 9.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.6 3.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.6 11.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.6 5.7 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.5 2.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.5 3.0 GO:0051036 regulation of endosome size(GO:0051036)
0.5 2.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.5 3.8 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.5 4.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 3.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.4 2.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.4 1.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 21.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.4 5.8 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.4 7.1 GO:0006012 galactose metabolic process(GO:0006012)
0.3 5.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.3 2.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.3 4.5 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2 3.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 3.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 8.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 1.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 13.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 3.6 GO:0015732 prostaglandin transport(GO:0015732)
0.2 3.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.2 1.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 15.8 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 6.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 6.3 GO:0097435 fibril organization(GO:0097435)
0.1 6.8 GO:0010039 response to iron ion(GO:0010039)
0.1 7.1 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 4.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 4.7 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 2.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 2.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.2 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.1 5.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 2.9 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.4 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 4.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 9.4 GO:0035264 multicellular organism growth(GO:0035264)
0.1 10.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 1.5 GO:0051412 response to corticosterone(GO:0051412)
0.1 0.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 7.2 GO:0070268 cornification(GO:0070268)
0.1 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 11.1 GO:0060173 appendage development(GO:0048736) limb development(GO:0060173)
0.1 1.7 GO:0003016 respiratory system process(GO:0003016)
0.1 3.2 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 3.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 2.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.8 GO:0042692 muscle cell differentiation(GO:0042692)
0.0 3.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 4.8 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 7.6 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 1.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.0 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036) positive regulation of amino acid transport(GO:0051957)
0.0 3.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.1 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 36.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.8 7.2 GO:0031417 NatC complex(GO:0031417)
1.4 6.8 GO:0005602 complement component C1 complex(GO:0005602)
1.3 4.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.2 4.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.2 10.7 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.9 15.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.8 25.1 GO:0000795 synaptonemal complex(GO:0000795)
0.7 11.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.6 4.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.5 6.2 GO:0016342 catenin complex(GO:0016342)
0.5 17.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.5 3.2 GO:0072487 MSL complex(GO:0072487)
0.4 3.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.4 2.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 6.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 27.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 15.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 22.3 GO:0043195 terminal bouton(GO:0043195)
0.3 3.1 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 3.8 GO:0005869 dynactin complex(GO:0005869)
0.2 5.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.9 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 3.4 GO:0031143 pseudopodium(GO:0031143)
0.1 10.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 9.7 GO:0000792 heterochromatin(GO:0000792)
0.1 11.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 7.5 GO:0016528 sarcoplasm(GO:0016528)
0.1 6.5 GO:0014704 intercalated disc(GO:0014704)
0.1 28.7 GO:0098793 presynapse(GO:0098793)
0.1 4.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 8.0 GO:0005604 basement membrane(GO:0005604)
0.1 3.1 GO:0043679 axon terminus(GO:0043679)
0.1 4.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 3.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.6 GO:0005861 troponin complex(GO:0005861)
0.1 9.3 GO:0000922 spindle pole(GO:0000922)
0.1 7.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.1 GO:0005902 microvillus(GO:0005902)
0.0 7.2 GO:0030496 midbody(GO:0030496)
0.0 3.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.9 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.9 GO:0043204 perikaryon(GO:0043204)
0.0 5.5 GO:0005938 cell cortex(GO:0005938)
0.0 1.9 GO:0005903 brush border(GO:0005903)
0.0 2.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 13.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 29.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
7.2 36.1 GO:0030348 syntaxin-3 binding(GO:0030348)
3.7 14.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
3.5 14.0 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
2.6 10.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
2.5 7.5 GO:0070538 oleic acid binding(GO:0070538)
2.2 17.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.9 5.8 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
1.4 4.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.2 4.8 GO:0035473 lipase binding(GO:0035473)
1.1 8.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.0 7.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.0 9.7 GO:0003696 satellite DNA binding(GO:0003696)
0.9 25.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.8 22.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.8 12.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.7 5.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.6 3.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.6 3.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.6 10.7 GO:0048156 tau protein binding(GO:0048156)
0.6 7.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.5 2.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.5 2.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.5 2.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.5 14.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.5 10.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 15.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.5 6.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 4.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.4 3.1 GO:0001515 opioid peptide activity(GO:0001515)
0.4 5.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4 7.2 GO:0031005 filamin binding(GO:0031005)
0.4 1.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.3 4.0 GO:0019534 toxin transporter activity(GO:0019534)
0.3 11.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 15.1 GO:0030507 spectrin binding(GO:0030507)
0.3 4.1 GO:0050693 LBD domain binding(GO:0050693)
0.3 6.0 GO:0035497 cAMP response element binding(GO:0035497)
0.3 3.1 GO:0097016 L27 domain binding(GO:0097016)
0.3 11.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 4.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 1.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 4.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 3.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 3.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 6.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 13.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 2.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 2.1 GO:0070700 BMP receptor binding(GO:0070700)
0.2 6.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 6.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 8.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 3.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 3.2 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 2.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 11.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 3.0 GO:0019003 GDP binding(GO:0019003)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 5.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 6.3 GO:0008201 heparin binding(GO:0008201)
0.0 4.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 5.7 GO:0003924 GTPase activity(GO:0003924)
0.0 4.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.2 GO:0008017 microtubule binding(GO:0008017)
0.0 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 8.3 GO:0003682 chromatin binding(GO:0003682)
0.0 2.3 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 39.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 15.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.4 13.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 14.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.3 4.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 11.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 14.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 5.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 4.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 5.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 3.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 3.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 4.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 3.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 4.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 7.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.1 PID BMP PATHWAY BMP receptor signaling
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 11.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 36.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.6 6.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.6 17.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 9.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.4 11.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 14.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 2.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 9.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 4.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 3.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.3 25.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 7.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 6.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 4.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 7.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 7.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 3.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 4.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 5.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 11.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 3.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 6.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 4.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 3.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 4.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.9 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 3.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 3.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 2.2 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism