Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for RAD21_SMC3
Z-value: 0.94
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Transcription factors associated with RAD21_SMC3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RAD21
|
ENSG00000164754.8 | RAD21 cohesin complex component |
|
SMC3
|
ENSG00000108055.9 | structural maintenance of chromosomes 3 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SMC3 | hg19_v2_chr10_+_112327425_112327516 | -0.39 | 3.5e-09 | Click! |
| RAD21 | hg19_v2_chr8_-_117886955_117887105 | -0.36 | 7.0e-08 | Click! |
Activity profile of RAD21_SMC3 motif
Sorted Z-values of RAD21_SMC3 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_30032610 | 24.13 |
ENST00000574405.1
|
DOC2A
|
double C2-like domains, alpha |
| chr13_-_88323218 | 18.98 |
ENST00000436290.2
ENST00000453832.2 ENST00000606590.1 |
MIR4500HG
|
MIR4500 host gene (non-protein coding) |
| chr3_-_138763734 | 16.11 |
ENST00000413199.1
ENST00000502927.2 |
PRR23C
|
proline rich 23C |
| chr1_+_10270863 | 15.65 |
ENST00000377093.4
ENST00000263934.6 |
KIF1B
|
kinesin family member 1B |
| chr5_-_136834982 | 15.58 |
ENST00000510689.1
ENST00000394945.1 |
SPOCK1
|
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| chr8_+_24772455 | 14.46 |
ENST00000433454.2
|
NEFM
|
neurofilament, medium polypeptide |
| chr1_+_10003486 | 13.78 |
ENST00000403197.1
ENST00000377205.1 |
NMNAT1
|
nicotinamide nucleotide adenylyltransferase 1 |
| chr1_-_35325400 | 12.51 |
ENST00000521580.2
|
SMIM12
|
small integral membrane protein 12 |
| chr16_-_19897455 | 12.42 |
ENST00000568214.1
ENST00000569479.1 |
GPRC5B
|
G protein-coupled receptor, family C, group 5, member B |
| chr1_-_156390128 | 11.79 |
ENST00000368242.3
|
C1orf61
|
chromosome 1 open reading frame 61 |
| chr9_+_130965651 | 11.78 |
ENST00000475805.1
ENST00000341179.7 ENST00000372923.3 |
DNM1
|
dynamin 1 |
| chr9_+_130965677 | 11.55 |
ENST00000393594.3
ENST00000486160.1 |
DNM1
|
dynamin 1 |
| chr7_+_156742399 | 11.01 |
ENST00000275820.3
|
NOM1
|
nucleolar protein with MIF4G domain 1 |
| chr8_-_67341208 | 10.54 |
ENST00000499642.1
|
RP11-346I3.4
|
RP11-346I3.4 |
| chr17_+_16593539 | 10.01 |
ENST00000340621.5
ENST00000399273.1 ENST00000443444.2 ENST00000360524.8 ENST00000456009.1 |
CCDC144A
|
coiled-coil domain containing 144A |
| chr10_-_79789291 | 9.98 |
ENST00000372371.3
|
POLR3A
|
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa |
| chr19_+_37407212 | 9.57 |
ENST00000427117.1
ENST00000587130.1 ENST00000333987.7 ENST00000415168.1 ENST00000444991.1 |
ZNF568
|
zinc finger protein 568 |
| chr11_-_64490634 | 9.50 |
ENST00000377559.3
ENST00000265459.6 |
NRXN2
|
neurexin 2 |
| chrX_+_11776410 | 9.35 |
ENST00000361672.2
|
MSL3
|
male-specific lethal 3 homolog (Drosophila) |
| chr4_+_7045042 | 9.22 |
ENST00000310074.7
ENST00000512388.1 |
TADA2B
|
transcriptional adaptor 2B |
| chr5_-_118324200 | 8.98 |
ENST00000515439.3
ENST00000510708.1 |
DTWD2
|
DTW domain containing 2 |
| chr5_+_157170703 | 8.87 |
ENST00000286307.5
|
LSM11
|
LSM11, U7 small nuclear RNA associated |
| chr1_-_212208842 | 8.12 |
ENST00000366992.3
ENST00000366993.3 ENST00000440600.2 ENST00000366994.3 |
INTS7
|
integrator complex subunit 7 |
| chr22_+_22901750 | 7.82 |
ENST00000407120.1
|
LL22NC03-63E9.3
|
Uncharacterized protein |
| chr19_-_58400148 | 7.80 |
ENST00000595048.1
ENST00000600634.1 ENST00000595295.1 ENST00000596604.1 ENST00000597342.1 ENST00000597807.1 |
ZNF814
|
zinc finger protein 814 |
| chr11_-_104480019 | 7.70 |
ENST00000536529.1
ENST00000545630.1 ENST00000538641.1 |
RP11-886D15.1
|
RP11-886D15.1 |
| chr7_+_302918 | 7.49 |
ENST00000599994.1
|
AC187652.1
|
Protein LOC100996433 |
| chr5_+_35617940 | 7.41 |
ENST00000282469.6
ENST00000509059.1 ENST00000356031.3 ENST00000510777.1 |
SPEF2
|
sperm flagellar 2 |
| chr10_+_17272608 | 7.28 |
ENST00000421459.2
|
VIM
|
vimentin |
| chr2_+_113342163 | 6.44 |
ENST00000409719.1
|
CHCHD5
|
coiled-coil-helix-coiled-coil-helix domain containing 5 |
| chr1_-_170043709 | 6.41 |
ENST00000367767.1
ENST00000361580.2 ENST00000538366.1 |
KIFAP3
|
kinesin-associated protein 3 |
| chr2_+_103089756 | 6.40 |
ENST00000295269.4
|
SLC9A4
|
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 |
| chr22_+_19705928 | 6.19 |
ENST00000383045.3
ENST00000438754.2 |
SEPT5
|
septin 5 |
| chr19_-_6481776 | 6.02 |
ENST00000543576.1
ENST00000590173.1 ENST00000381480.2 |
DENND1C
|
DENN/MADD domain containing 1C |
| chr17_-_37308824 | 6.01 |
ENST00000415163.1
ENST00000441877.1 ENST00000444911.2 |
PLXDC1
|
plexin domain containing 1 |
| chr11_+_120039685 | 5.91 |
ENST00000530303.1
ENST00000319763.1 |
AP000679.2
|
Uncharacterized protein |
| chr19_-_48823332 | 5.90 |
ENST00000315396.7
|
CCDC114
|
coiled-coil domain containing 114 |
| chr11_-_85565906 | 5.89 |
ENST00000544076.1
|
AP000974.1
|
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein |
| chr7_-_91509986 | 5.80 |
ENST00000456229.1
ENST00000442961.1 ENST00000406735.2 ENST00000419292.1 ENST00000351870.3 |
MTERF
|
mitochondrial transcription termination factor |
| chr6_+_127587755 | 5.74 |
ENST00000368314.1
ENST00000476956.1 ENST00000609447.1 ENST00000356799.2 ENST00000477776.1 ENST00000609944.1 |
RNF146
|
ring finger protein 146 |
| chr7_-_100171270 | 5.50 |
ENST00000538735.1
|
SAP25
|
Sin3A-associated protein, 25kDa |
| chr10_-_15413035 | 5.49 |
ENST00000378116.4
ENST00000455654.1 |
FAM171A1
|
family with sequence similarity 171, member A1 |
| chr2_-_232395169 | 5.47 |
ENST00000305141.4
|
NMUR1
|
neuromedin U receptor 1 |
| chr8_-_66474884 | 5.43 |
ENST00000520902.1
|
CTD-3025N20.2
|
CTD-3025N20.2 |
| chr16_+_48657361 | 5.43 |
ENST00000565072.1
|
RP11-42I10.1
|
RP11-42I10.1 |
| chr19_-_19754354 | 5.35 |
ENST00000587238.1
|
GMIP
|
GEM interacting protein |
| chr19_-_58400372 | 5.22 |
ENST00000597832.1
ENST00000435989.2 |
ZNF814
|
zinc finger protein 814 |
| chr5_-_146833485 | 5.22 |
ENST00000398514.3
|
DPYSL3
|
dihydropyrimidinase-like 3 |
| chr11_-_130786400 | 5.20 |
ENST00000265909.4
|
SNX19
|
sorting nexin 19 |
| chr19_-_49339080 | 5.07 |
ENST00000595764.1
|
HSD17B14
|
hydroxysteroid (17-beta) dehydrogenase 14 |
| chr17_+_45810594 | 5.05 |
ENST00000177694.1
|
TBX21
|
T-box 21 |
| chr17_-_37309480 | 5.05 |
ENST00000539608.1
|
PLXDC1
|
plexin domain containing 1 |
| chr16_+_1756162 | 5.03 |
ENST00000250894.4
ENST00000356010.5 |
MAPK8IP3
|
mitogen-activated protein kinase 8 interacting protein 3 |
| chr5_+_54455946 | 5.01 |
ENST00000503787.1
ENST00000296734.6 ENST00000515370.1 |
GPX8
|
glutathione peroxidase 8 (putative) |
| chr21_+_41239243 | 4.92 |
ENST00000328619.5
|
PCP4
|
Purkinje cell protein 4 |
| chr19_+_47852538 | 4.86 |
ENST00000328771.4
|
DHX34
|
DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| chr3_+_5163905 | 4.83 |
ENST00000256496.3
ENST00000419534.2 |
ARL8B
|
ADP-ribosylation factor-like 8B |
| chr19_-_22034809 | 4.80 |
ENST00000594012.1
ENST00000595461.1 ENST00000596899.1 |
ZNF43
|
zinc finger protein 43 |
| chr4_+_71570430 | 4.78 |
ENST00000417478.2
|
RUFY3
|
RUN and FYVE domain containing 3 |
| chr15_-_38856836 | 4.76 |
ENST00000450598.2
ENST00000559830.1 ENST00000558164.1 ENST00000310803.5 |
RASGRP1
|
RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| chr20_+_3801162 | 4.74 |
ENST00000379573.2
ENST00000379567.2 ENST00000455742.1 ENST00000246041.2 |
AP5S1
|
adaptor-related protein complex 5, sigma 1 subunit |
| chr5_-_140998481 | 4.71 |
ENST00000518047.1
|
DIAPH1
|
diaphanous-related formin 1 |
| chr19_-_19754404 | 4.70 |
ENST00000587205.1
ENST00000445806.2 ENST00000203556.4 |
GMIP
|
GEM interacting protein |
| chr17_-_41466555 | 4.67 |
ENST00000586231.1
|
LINC00910
|
long intergenic non-protein coding RNA 910 |
| chr16_-_49315731 | 4.63 |
ENST00000219197.6
|
CBLN1
|
cerebellin 1 precursor |
| chr10_+_99332529 | 4.63 |
ENST00000455090.1
|
ANKRD2
|
ankyrin repeat domain 2 (stretch responsive muscle) |
| chr1_+_178511876 | 4.57 |
ENST00000367638.1
ENST00000367636.4 |
C1orf220
C1ORF220
|
chromosome 1 open reading frame 220 C1ORF220 |
| chr12_+_13197218 | 4.55 |
ENST00000197268.8
|
KIAA1467
|
KIAA1467 |
| chr8_+_28480246 | 4.51 |
ENST00000523149.1
|
EXTL3
|
exostosin-like glycosyltransferase 3 |
| chr17_-_4890919 | 4.48 |
ENST00000572543.1
ENST00000381311.5 ENST00000348066.3 ENST00000358183.4 |
CAMTA2
|
calmodulin binding transcription activator 2 |
| chr12_-_102224457 | 4.47 |
ENST00000549165.1
ENST00000549940.1 ENST00000392919.4 |
GNPTAB
|
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| chr11_-_117103208 | 4.46 |
ENST00000320934.3
ENST00000530269.1 |
PCSK7
|
proprotein convertase subtilisin/kexin type 7 |
| chr17_+_76356516 | 4.45 |
ENST00000592569.1
|
RP11-806H10.4
|
RP11-806H10.4 |
| chr9_+_91933726 | 4.40 |
ENST00000534113.2
|
SECISBP2
|
SECIS binding protein 2 |
| chr19_-_49149553 | 4.30 |
ENST00000084798.4
|
CA11
|
carbonic anhydrase XI |
| chr6_-_41747595 | 4.28 |
ENST00000373018.3
|
FRS3
|
fibroblast growth factor receptor substrate 3 |
| chr19_+_8478154 | 4.18 |
ENST00000381035.4
ENST00000595142.1 ENST00000601724.1 ENST00000393944.1 ENST00000215555.2 ENST00000601283.1 ENST00000595213.1 |
MARCH2
|
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase |
| chr17_-_8868991 | 4.17 |
ENST00000447110.1
|
PIK3R5
|
phosphoinositide-3-kinase, regulatory subunit 5 |
| chr14_-_75079026 | 4.17 |
ENST00000261978.4
|
LTBP2
|
latent transforming growth factor beta binding protein 2 |
| chr22_+_22786288 | 4.16 |
ENST00000390301.2
|
IGLV1-36
|
immunoglobulin lambda variable 1-36 |
| chr6_+_127588020 | 4.14 |
ENST00000309649.3
ENST00000610162.1 ENST00000610153.1 ENST00000608991.1 ENST00000480444.1 |
RNF146
|
ring finger protein 146 |
| chr5_+_140254884 | 4.14 |
ENST00000398631.2
|
PCDHA12
|
protocadherin alpha 12 |
| chrX_+_77166172 | 4.12 |
ENST00000343533.5
ENST00000350425.4 ENST00000341514.6 |
ATP7A
|
ATPase, Cu++ transporting, alpha polypeptide |
| chr16_+_58533951 | 4.10 |
ENST00000566192.1
ENST00000565088.1 ENST00000568640.1 ENST00000563978.1 ENST00000569923.1 ENST00000356752.4 ENST00000563799.1 ENST00000562999.1 ENST00000570248.1 ENST00000562731.1 ENST00000568424.1 |
NDRG4
|
NDRG family member 4 |
| chr15_-_64338521 | 4.07 |
ENST00000457488.1
ENST00000558069.1 |
DAPK2
|
death-associated protein kinase 2 |
| chr10_+_99332198 | 4.05 |
ENST00000307518.5
ENST00000298808.5 ENST00000370655.1 |
ANKRD2
|
ankyrin repeat domain 2 (stretch responsive muscle) |
| chrX_+_11776278 | 4.01 |
ENST00000312196.4
ENST00000337339.2 |
MSL3
|
male-specific lethal 3 homolog (Drosophila) |
| chr2_-_132559234 | 4.01 |
ENST00000303798.2
|
C2orf27B
|
chromosome 2 open reading frame 27B |
| chr17_-_8286484 | 4.01 |
ENST00000582556.1
ENST00000584164.1 ENST00000293842.5 ENST00000584343.1 ENST00000578812.1 ENST00000583011.1 |
RPL26
|
ribosomal protein L26 |
| chr5_+_148521381 | 3.96 |
ENST00000504238.1
|
ABLIM3
|
actin binding LIM protein family, member 3 |
| chr12_-_7245125 | 3.93 |
ENST00000542285.1
ENST00000540610.1 |
C1R
|
complement component 1, r subcomponent |
| chr9_-_134615443 | 3.92 |
ENST00000372195.1
|
RAPGEF1
|
Rap guanine nucleotide exchange factor (GEF) 1 |
| chr17_-_34890759 | 3.91 |
ENST00000431794.3
|
MYO19
|
myosin XIX |
| chr8_-_48651648 | 3.91 |
ENST00000408965.3
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta |
| chr1_+_18081804 | 3.90 |
ENST00000375406.1
|
ACTL8
|
actin-like 8 |
| chr17_-_7518145 | 3.84 |
ENST00000250113.7
ENST00000571597.1 |
FXR2
|
fragile X mental retardation, autosomal homolog 2 |
| chr19_-_46318486 | 3.74 |
ENST00000597055.1
|
RSPH6A
|
radial spoke head 6 homolog A (Chlamydomonas) |
| chr8_-_101571933 | 3.74 |
ENST00000520311.1
|
ANKRD46
|
ankyrin repeat domain 46 |
| chr9_-_94712434 | 3.69 |
ENST00000375708.3
|
ROR2
|
receptor tyrosine kinase-like orphan receptor 2 |
| chr2_-_166060552 | 3.67 |
ENST00000283254.7
ENST00000453007.1 |
SCN3A
|
sodium channel, voltage-gated, type III, alpha subunit |
| chrX_-_30326445 | 3.65 |
ENST00000378963.1
|
NR0B1
|
nuclear receptor subfamily 0, group B, member 1 |
| chrX_+_153029633 | 3.64 |
ENST00000538966.1
ENST00000361971.5 ENST00000538776.1 ENST00000538543.1 |
PLXNB3
|
plexin B3 |
| chr12_+_53773944 | 3.62 |
ENST00000551969.1
ENST00000327443.4 |
SP1
|
Sp1 transcription factor |
| chr15_+_71185148 | 3.56 |
ENST00000443425.2
ENST00000560755.1 |
LRRC49
|
leucine rich repeat containing 49 |
| chrX_+_11776701 | 3.52 |
ENST00000476743.1
ENST00000421368.2 ENST00000398527.2 |
MSL3
|
male-specific lethal 3 homolog (Drosophila) |
| chr17_-_1090599 | 3.52 |
ENST00000544583.2
|
ABR
|
active BCR-related |
| chr9_+_100174344 | 3.52 |
ENST00000422139.2
|
TDRD7
|
tudor domain containing 7 |
| chr11_+_2421718 | 3.47 |
ENST00000380996.5
ENST00000333256.6 ENST00000380992.1 ENST00000437110.1 ENST00000435795.1 |
TSSC4
|
tumor suppressing subtransferable candidate 4 |
| chr5_+_148521136 | 3.47 |
ENST00000506113.1
|
ABLIM3
|
actin binding LIM protein family, member 3 |
| chr17_+_43971643 | 3.46 |
ENST00000344290.5
ENST00000262410.5 ENST00000351559.5 ENST00000340799.5 ENST00000535772.1 ENST00000347967.5 |
MAPT
|
microtubule-associated protein tau |
| chr19_+_12949251 | 3.46 |
ENST00000251472.4
|
MAST1
|
microtubule associated serine/threonine kinase 1 |
| chr16_+_23569021 | 3.42 |
ENST00000567212.1
ENST00000567264.1 |
UBFD1
|
ubiquitin family domain containing 1 |
| chr8_-_146012660 | 3.42 |
ENST00000343459.4
ENST00000429371.2 ENST00000534445.1 |
ZNF34
|
zinc finger protein 34 |
| chr22_-_22292934 | 3.42 |
ENST00000538191.1
ENST00000424647.1 ENST00000407142.1 |
PPM1F
|
protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| chr22_-_22307199 | 3.41 |
ENST00000397495.4
ENST00000263212.5 |
PPM1F
|
protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| chr2_-_74710078 | 3.41 |
ENST00000290418.4
|
CCDC142
|
coiled-coil domain containing 142 |
| chr16_+_30759700 | 3.41 |
ENST00000328273.7
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis) |
| chr17_-_4890649 | 3.36 |
ENST00000361571.5
|
CAMTA2
|
calmodulin binding transcription activator 2 |
| chr17_+_43972010 | 3.34 |
ENST00000334239.8
ENST00000446361.3 |
MAPT
|
microtubule-associated protein tau |
| chr3_-_183735731 | 3.33 |
ENST00000334444.6
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| chr17_-_26220366 | 3.32 |
ENST00000460380.2
ENST00000508862.1 ENST00000379102.3 ENST00000582441.1 |
LYRM9
RP1-66C13.4
|
LYR motif containing 9 Uncharacterized protein |
| chr6_+_31105426 | 3.32 |
ENST00000547221.1
|
PSORS1C1
|
psoriasis susceptibility 1 candidate 1 |
| chr2_+_166095898 | 3.31 |
ENST00000424833.1
ENST00000375437.2 ENST00000357398.3 |
SCN2A
|
sodium channel, voltage-gated, type II, alpha subunit |
| chr16_+_89642120 | 3.29 |
ENST00000268720.5
ENST00000319518.8 |
CPNE7
|
copine VII |
| chr10_-_6622258 | 3.26 |
ENST00000263125.5
|
PRKCQ
|
protein kinase C, theta |
| chr15_-_79103757 | 3.25 |
ENST00000388820.4
|
ADAMTS7
|
ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| chr2_-_175351744 | 3.20 |
ENST00000295500.4
ENST00000392552.2 ENST00000392551.2 |
GPR155
|
G protein-coupled receptor 155 |
| chr4_+_56814968 | 3.20 |
ENST00000422247.2
|
CEP135
|
centrosomal protein 135kDa |
| chr3_+_50712672 | 3.19 |
ENST00000266037.9
|
DOCK3
|
dedicator of cytokinesis 3 |
| chr9_+_133884469 | 3.07 |
ENST00000361069.4
|
LAMC3
|
laminin, gamma 3 |
| chr8_-_145669791 | 3.02 |
ENST00000409379.3
|
TONSL
|
tonsoku-like, DNA repair protein |
| chr17_-_9862772 | 3.01 |
ENST00000580865.1
ENST00000583882.1 |
GAS7
|
growth arrest-specific 7 |
| chrX_+_49020121 | 3.00 |
ENST00000415364.1
ENST00000376338.3 ENST00000425285.1 |
MAGIX
|
MAGI family member, X-linked |
| chr22_+_23040274 | 3.00 |
ENST00000390306.2
|
IGLV2-23
|
immunoglobulin lambda variable 2-23 |
| chr14_+_22446680 | 2.99 |
ENST00000390443.3
|
TRAV8-6
|
T cell receptor alpha variable 8-6 |
| chr5_+_148521046 | 2.95 |
ENST00000326685.7
ENST00000356541.3 ENST00000309868.7 |
ABLIM3
|
actin binding LIM protein family, member 3 |
| chr9_-_140317605 | 2.93 |
ENST00000479452.1
ENST00000465160.2 |
EXD3
|
exonuclease 3'-5' domain containing 3 |
| chr2_+_131113609 | 2.92 |
ENST00000347849.3
|
PTPN18
|
protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| chr10_-_6622201 | 2.90 |
ENST00000539722.1
ENST00000397176.2 |
PRKCQ
|
protein kinase C, theta |
| chr14_-_91526922 | 2.87 |
ENST00000418736.2
ENST00000261991.3 |
RPS6KA5
|
ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| chr2_-_166060571 | 2.86 |
ENST00000360093.3
|
SCN3A
|
sodium channel, voltage-gated, type III, alpha subunit |
| chr9_-_139922726 | 2.80 |
ENST00000265662.5
ENST00000371605.3 |
ABCA2
|
ATP-binding cassette, sub-family A (ABC1), member 2 |
| chr9_-_139922631 | 2.78 |
ENST00000341511.6
|
ABCA2
|
ATP-binding cassette, sub-family A (ABC1), member 2 |
| chr12_-_121410095 | 2.77 |
ENST00000539163.1
|
AC079602.1
|
AC079602.1 |
| chr3_-_194991876 | 2.73 |
ENST00000310380.6
|
XXYLT1
|
xyloside xylosyltransferase 1 |
| chr10_-_30024716 | 2.68 |
ENST00000375398.2
ENST00000375400.3 |
SVIL
|
supervillin |
| chr19_-_22034770 | 2.66 |
ENST00000598381.1
|
ZNF43
|
zinc finger protein 43 |
| chr15_-_71407806 | 2.64 |
ENST00000566432.1
ENST00000567117.1 |
CT62
|
cancer/testis antigen 62 |
| chr7_-_19748640 | 2.61 |
ENST00000222567.5
|
TWISTNB
|
TWIST neighbor |
| chr9_+_139560197 | 2.58 |
ENST00000371698.3
|
EGFL7
|
EGF-like-domain, multiple 7 |
| chr15_-_34659349 | 2.54 |
ENST00000314891.6
|
LPCAT4
|
lysophosphatidylcholine acyltransferase 4 |
| chr11_-_118436606 | 2.51 |
ENST00000530872.1
|
IFT46
|
intraflagellar transport 46 homolog (Chlamydomonas) |
| chr11_+_7110165 | 2.49 |
ENST00000306904.5
|
RBMXL2
|
RNA binding motif protein, X-linked-like 2 |
| chr4_+_128886424 | 2.49 |
ENST00000398965.1
|
C4orf29
|
chromosome 4 open reading frame 29 |
| chr10_-_49732281 | 2.48 |
ENST00000374170.1
|
ARHGAP22
|
Rho GTPase activating protein 22 |
| chr1_+_168148273 | 2.47 |
ENST00000367830.3
|
TIPRL
|
TIP41, TOR signaling pathway regulator-like (S. cerevisiae) |
| chr21_-_36262032 | 2.45 |
ENST00000325074.5
ENST00000399237.2 |
RUNX1
|
runt-related transcription factor 1 |
| chr12_+_53440753 | 2.43 |
ENST00000379902.3
|
TENC1
|
tensin like C1 domain containing phosphatase (tensin 2) |
| chr7_-_37488834 | 2.39 |
ENST00000310758.4
|
ELMO1
|
engulfment and cell motility 1 |
| chr11_+_67033881 | 2.39 |
ENST00000308595.5
ENST00000526285.1 |
ADRBK1
|
adrenergic, beta, receptor kinase 1 |
| chr14_+_22337014 | 2.38 |
ENST00000390436.2
|
TRAV13-1
|
T cell receptor alpha variable 13-1 |
| chr16_-_2390704 | 2.36 |
ENST00000301732.5
ENST00000382381.3 |
ABCA3
|
ATP-binding cassette, sub-family A (ABC1), member 3 |
| chr14_+_24630465 | 2.35 |
ENST00000557894.1
ENST00000559284.1 ENST00000560275.1 |
IRF9
|
interferon regulatory factor 9 |
| chr9_+_100174232 | 2.33 |
ENST00000355295.4
|
TDRD7
|
tudor domain containing 7 |
| chr5_+_140165876 | 2.31 |
ENST00000504120.2
ENST00000394633.3 ENST00000378133.3 |
PCDHA1
|
protocadherin alpha 1 |
| chr11_-_64510409 | 2.30 |
ENST00000394429.1
ENST00000394428.1 |
RASGRP2
|
RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| chr1_+_37940153 | 2.30 |
ENST00000373087.6
|
ZC3H12A
|
zinc finger CCCH-type containing 12A |
| chr7_-_122526799 | 2.28 |
ENST00000334010.7
ENST00000313070.7 |
CADPS2
|
Ca++-dependent secretion activator 2 |
| chr11_-_63536113 | 2.27 |
ENST00000433688.1
ENST00000546282.2 |
C11orf95
RP11-466C23.4
|
chromosome 11 open reading frame 95 RP11-466C23.4 |
| chr19_-_46318561 | 2.26 |
ENST00000221538.3
|
RSPH6A
|
radial spoke head 6 homolog A (Chlamydomonas) |
| chr5_-_140998616 | 2.26 |
ENST00000389054.3
ENST00000398562.2 ENST00000389057.5 ENST00000398566.3 ENST00000398557.4 ENST00000253811.6 |
DIAPH1
|
diaphanous-related formin 1 |
| chr16_-_790887 | 2.25 |
ENST00000540986.1
|
NARFL
|
nuclear prelamin A recognition factor-like |
| chr16_-_790982 | 2.24 |
ENST00000301694.5
ENST00000251588.2 |
NARFL
|
nuclear prelamin A recognition factor-like |
| chr14_-_77787198 | 2.20 |
ENST00000261534.4
|
POMT2
|
protein-O-mannosyltransferase 2 |
| chr12_+_121078355 | 2.20 |
ENST00000316803.3
|
CABP1
|
calcium binding protein 1 |
| chr3_+_134514093 | 2.16 |
ENST00000398015.3
|
EPHB1
|
EPH receptor B1 |
| chr12_-_65515334 | 2.15 |
ENST00000286574.4
|
WIF1
|
WNT inhibitory factor 1 |
| chr19_-_6279932 | 2.12 |
ENST00000252674.7
|
MLLT1
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
| chr12_-_1058685 | 2.12 |
ENST00000397230.2
ENST00000542785.1 ENST00000544742.1 ENST00000536177.1 ENST00000539046.1 ENST00000541619.1 |
RAD52
|
RAD52 homolog (S. cerevisiae) |
| chr22_-_22901636 | 2.10 |
ENST00000406503.1
ENST00000439106.1 ENST00000402697.1 ENST00000543184.1 ENST00000398743.2 |
PRAME
|
preferentially expressed antigen in melanoma |
| chr6_+_138188551 | 2.09 |
ENST00000237289.4
ENST00000433680.1 |
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr17_+_47653178 | 2.09 |
ENST00000328741.5
|
NXPH3
|
neurexophilin 3 |
| chr8_-_101571964 | 2.08 |
ENST00000520552.1
ENST00000521345.1 ENST00000523000.1 ENST00000335659.3 ENST00000358990.3 ENST00000519597.1 |
ANKRD46
|
ankyrin repeat domain 46 |
| chr19_+_45842445 | 2.08 |
ENST00000598357.1
|
L47234.1
|
Uncharacterized protein |
| chr4_+_128886532 | 2.07 |
ENST00000444616.1
ENST00000388795.5 |
C4orf29
|
chromosome 4 open reading frame 29 |
| chr15_+_63340775 | 2.07 |
ENST00000559281.1
ENST00000317516.7 |
TPM1
|
tropomyosin 1 (alpha) |
| chr17_+_1958388 | 2.05 |
ENST00000399849.3
|
HIC1
|
hypermethylated in cancer 1 |
| chr15_-_71407833 | 2.04 |
ENST00000449977.2
|
CT62
|
cancer/testis antigen 62 |
| chr6_-_41703296 | 1.97 |
ENST00000373033.1
|
TFEB
|
transcription factor EB |
| chr1_-_146644036 | 1.97 |
ENST00000425272.2
|
PRKAB2
|
protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| chr15_-_58358607 | 1.96 |
ENST00000249750.4
|
ALDH1A2
|
aldehyde dehydrogenase 1 family, member A2 |
| chr4_+_75858318 | 1.95 |
ENST00000307428.7
|
PARM1
|
prostate androgen-regulated mucin-like protein 1 |
| chr8_+_42128812 | 1.94 |
ENST00000520810.1
ENST00000416505.2 ENST00000519735.1 ENST00000520835.1 ENST00000379708.3 |
IKBKB
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| chr9_+_91933407 | 1.94 |
ENST00000375807.3
ENST00000339901.4 |
SECISBP2
|
SECIS binding protein 2 |
| chr2_+_220492373 | 1.93 |
ENST00000317151.3
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3 |
| chr6_-_11044509 | 1.92 |
ENST00000354666.3
|
ELOVL2
|
ELOVL fatty acid elongase 2 |
| chr7_-_99679324 | 1.92 |
ENST00000292393.5
ENST00000413658.2 ENST00000412947.1 ENST00000441298.1 ENST00000449785.1 ENST00000299667.4 ENST00000424697.1 |
ZNF3
|
zinc finger protein 3 |
| chr10_-_76868931 | 1.91 |
ENST00000372700.3
ENST00000473072.2 ENST00000491677.2 ENST00000607131.1 ENST00000372702.3 |
DUSP13
|
dual specificity phosphatase 13 |
| chr7_-_122526499 | 1.91 |
ENST00000412584.2
|
CADPS2
|
Ca++-dependent secretion activator 2 |
| chr2_+_231729615 | 1.90 |
ENST00000326427.6
ENST00000335005.6 ENST00000326407.6 |
ITM2C
|
integral membrane protein 2C |
Network of associatons between targets according to the STRING database.
First level regulatory network of RAD21_SMC3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.8 | 23.3 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 5.2 | 15.7 | GO:1904647 | response to rotenone(GO:1904647) |
| 4.8 | 14.5 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 2.1 | 6.4 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 2.1 | 2.1 | GO:0070428 | regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) |
| 1.8 | 8.9 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 1.7 | 5.2 | GO:1990502 | dense core granule maturation(GO:1990502) |
| 1.7 | 3.4 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 1.5 | 6.2 | GO:2000569 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
| 1.5 | 13.8 | GO:0006531 | aspartate metabolic process(GO:0006531) |
| 1.4 | 6.8 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 1.2 | 11.2 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 1.2 | 3.6 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 1.2 | 9.5 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 1.2 | 3.5 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 1.1 | 5.6 | GO:0032377 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.9 | 4.6 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) positive regulation of long term synaptic depression(GO:1900454) |
| 0.9 | 6.2 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.8 | 3.3 | GO:1903597 | negative regulation of gap junction assembly(GO:1903597) |
| 0.8 | 4.0 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.8 | 4.8 | GO:0032252 | secretory granule localization(GO:0032252) |
| 0.8 | 2.3 | GO:0000294 | nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) negative regulation by host of viral genome replication(GO:0044828) |
| 0.7 | 3.7 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.7 | 12.4 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.7 | 2.2 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) trans-synaptic signaling by trans-synaptic complex(GO:0099545) |
| 0.7 | 4.2 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 0.7 | 7.6 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.7 | 6.8 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.7 | 4.1 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.7 | 2.7 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.7 | 8.1 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.7 | 11.2 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.6 | 3.2 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164) |
| 0.6 | 1.9 | GO:0060168 | positive regulation of adenosine receptor signaling pathway(GO:0060168) |
| 0.6 | 3.7 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 0.6 | 1.8 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.6 | 24.1 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.6 | 1.7 | GO:0090290 | positive regulation of osteoclast proliferation(GO:0090290) |
| 0.5 | 7.0 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.5 | 11.0 | GO:0048820 | hair follicle maturation(GO:0048820) |
| 0.5 | 5.2 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.5 | 6.4 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.5 | 5.9 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.5 | 2.9 | GO:0036166 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 0.5 | 1.9 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.5 | 1.4 | GO:0071907 | determination of digestive tract left/right asymmetry(GO:0071907) |
| 0.5 | 15.7 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.5 | 1.4 | GO:1901202 | negative regulation of extracellular matrix assembly(GO:1901202) |
| 0.5 | 2.8 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.5 | 0.5 | GO:0000189 | MAPK import into nucleus(GO:0000189) |
| 0.5 | 3.6 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.4 | 5.8 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.4 | 2.2 | GO:1904098 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.4 | 1.3 | GO:0071301 | cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404) |
| 0.4 | 2.1 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.4 | 6.8 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.4 | 1.7 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.4 | 6.7 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.4 | 5.9 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.4 | 2.7 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.4 | 4.6 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.4 | 1.9 | GO:0044026 | DNA hypermethylation(GO:0044026) |
| 0.4 | 4.5 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 0.4 | 1.1 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.4 | 1.1 | GO:0002476 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) |
| 0.4 | 1.1 | GO:0033242 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.3 | 1.4 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.3 | 1.0 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.3 | 5.1 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.3 | 3.6 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.3 | 3.2 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.3 | 1.9 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 1.3 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 0.3 | 1.6 | GO:1990834 | response to odorant(GO:1990834) |
| 0.3 | 0.9 | GO:1902809 | skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 0.3 | 1.5 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.3 | 0.9 | GO:0031627 | telomeric loop formation(GO:0031627) |
| 0.3 | 7.8 | GO:0003299 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.3 | 1.4 | GO:0090650 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.3 | 31.5 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.3 | 5.9 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.3 | 3.5 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.3 | 1.3 | GO:0099551 | synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) |
| 0.3 | 1.0 | GO:2000980 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.3 | 0.8 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.3 | 3.3 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.2 | 5.8 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.2 | 1.0 | GO:1901490 | regulation of lymphangiogenesis(GO:1901490) |
| 0.2 | 3.1 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.2 | 1.9 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 0.2 | 11.8 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.2 | 7.7 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.2 | 1.8 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.2 | 1.1 | GO:0002865 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) |
| 0.2 | 2.0 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.2 | 4.8 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.2 | 3.2 | GO:0050890 | cognition(GO:0050890) |
| 0.2 | 1.0 | GO:0003051 | angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106) |
| 0.2 | 3.6 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.2 | 1.8 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.2 | 0.6 | GO:0070781 | response to biotin(GO:0070781) |
| 0.2 | 10.0 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.2 | 1.1 | GO:1904259 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.2 | 5.1 | GO:0015012 | heparan sulfate proteoglycan biosynthetic process(GO:0015012) |
| 0.2 | 0.2 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
| 0.2 | 1.0 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.2 | 1.3 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.2 | 0.6 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.2 | 13.1 | GO:0010812 | negative regulation of cell-substrate adhesion(GO:0010812) |
| 0.2 | 0.8 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.2 | 2.6 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.1 | 2.7 | GO:0060828 | regulation of canonical Wnt signaling pathway(GO:0060828) |
| 0.1 | 0.4 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 2.5 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.1 | 0.6 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.1 | 2.1 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.1 | 1.4 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.1 | 5.0 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.1 | 7.1 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.1 | 4.2 | GO:0097435 | fibril organization(GO:0097435) |
| 0.1 | 1.2 | GO:0035791 | platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) |
| 0.1 | 2.4 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.1 | 1.2 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.1 | 1.4 | GO:0035878 | nail development(GO:0035878) |
| 0.1 | 3.6 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.1 | 3.9 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.1 | 2.5 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 4.5 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 0.4 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.1 | 1.8 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.1 | 2.9 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.1 | 1.0 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.1 | 4.2 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
| 0.1 | 0.7 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.1 | 0.4 | GO:0061047 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047) |
| 0.1 | 1.4 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.1 | 8.1 | GO:0021510 | spinal cord development(GO:0021510) |
| 0.1 | 0.7 | GO:0071351 | interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351) |
| 0.1 | 1.6 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.8 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.1 | 0.8 | GO:0015697 | quaternary ammonium group transport(GO:0015697) |
| 0.1 | 0.8 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.1 | 0.8 | GO:0002911 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 0.1 | 0.6 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.1 | 1.2 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 1.3 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.1 | 0.4 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.1 | 3.2 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.1 | 2.4 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.1 | 5.0 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.1 | 0.3 | GO:0002266 | follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268) |
| 0.1 | 2.5 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 3.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 0.9 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.1 | 4.0 | GO:1901185 | negative regulation of ERBB signaling pathway(GO:1901185) |
| 0.1 | 1.1 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.1 | 3.3 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 1.7 | GO:0019216 | regulation of lipid metabolic process(GO:0019216) |
| 0.1 | 1.3 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.1 | 0.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 2.1 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 0.4 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.1 | 1.9 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 0.8 | GO:0015732 | prostaglandin transport(GO:0015732) |
| 0.1 | 1.5 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 0.7 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 1.1 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.0 | 0.5 | GO:0060605 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.0 | 1.7 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 2.0 | GO:0042308 | negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590) |
| 0.0 | 0.9 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 1.6 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.4 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.0 | 0.3 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 1.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.2 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.0 | 1.6 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.0 | 0.8 | GO:0046546 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 3.9 | GO:0031638 | zymogen activation(GO:0031638) |
| 0.0 | 1.6 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.6 | GO:0030818 | negative regulation of cAMP biosynthetic process(GO:0030818) |
| 0.0 | 1.0 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.0 | 1.3 | GO:0048477 | oogenesis(GO:0048477) |
| 0.0 | 2.1 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 1.8 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 0.0 | 2.1 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 2.4 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.0 | 0.3 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.0 | 0.1 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.0 | 0.7 | GO:0002042 | cell migration involved in sprouting angiogenesis(GO:0002042) |
| 0.0 | 1.8 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 2.2 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 2.6 | GO:0048839 | inner ear development(GO:0048839) |
| 0.0 | 1.4 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 2.7 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
| 0.0 | 0.6 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.0 | 0.6 | GO:0060348 | bone development(GO:0060348) |
| 0.0 | 0.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 2.4 | GO:0051384 | response to glucocorticoid(GO:0051384) |
| 0.0 | 0.3 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 0.7 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.7 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.2 | GO:0042737 | drug catabolic process(GO:0042737) |
| 0.0 | 1.8 | GO:0006470 | protein dephosphorylation(GO:0006470) |
| 0.0 | 0.2 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.0 | 0.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.0 | 0.3 | GO:0051194 | positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
| 0.0 | 0.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.4 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.9 | GO:0021915 | neural tube development(GO:0021915) |
| 0.0 | 0.9 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 0.1 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 0.4 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 16.9 | GO:0072487 | MSL complex(GO:0072487) |
| 1.6 | 6.4 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 1.4 | 4.2 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 1.4 | 6.8 | GO:0045298 | tubulin complex(GO:0045298) |
| 1.1 | 14.5 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 1.1 | 8.9 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 1.1 | 1.1 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.9 | 8.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.7 | 5.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.7 | 6.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.7 | 18.7 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.7 | 2.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.6 | 4.5 | GO:0097361 | CIA complex(GO:0097361) |
| 0.6 | 2.4 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.6 | 9.2 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.5 | 5.8 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.5 | 1.5 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
| 0.5 | 1.5 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.5 | 5.6 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.5 | 23.8 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.4 | 2.7 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.4 | 2.3 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.4 | 3.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.4 | 15.7 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.3 | 3.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.3 | 1.6 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.3 | 0.9 | GO:0016938 | kinesin I complex(GO:0016938) |
| 0.3 | 2.4 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.3 | 1.5 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.2 | 3.6 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.2 | 21.5 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.2 | 4.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 5.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.2 | 3.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 1.2 | GO:1990130 | EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.2 | 4.8 | GO:0071437 | invadopodium(GO:0071437) |
| 0.2 | 0.6 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.2 | 1.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.2 | 2.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 1.5 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.2 | 6.3 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.2 | 1.1 | GO:0042825 | TAP complex(GO:0042825) |
| 0.2 | 1.4 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.2 | 1.0 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.2 | 2.3 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 6.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.2 | 4.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 6.2 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 7.2 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 2.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 3.9 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.1 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 2.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 8.6 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 0.6 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 13.2 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 10.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 1.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 4.9 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.1 | 5.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 0.9 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 1.8 | GO:0032982 | myosin filament(GO:0032982) |
| 0.1 | 3.4 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 5.0 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 1.5 | GO:0097546 | ciliary base(GO:0097546) |
| 0.1 | 0.6 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.1 | 0.8 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 6.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 1.7 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.1 | 1.4 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.1 | 21.0 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 0.3 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 0.1 | 0.7 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 0.9 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 8.6 | GO:0031674 | I band(GO:0031674) |
| 0.1 | 5.2 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 6.8 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 6.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 4.7 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 0.2 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.0 | 4.1 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 1.4 | GO:0036379 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.0 | 0.5 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.0 | 2.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.0 | 2.4 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 11.1 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 13.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 3.3 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 1.3 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 3.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.4 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 0.3 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 6.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.3 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.0 | 1.3 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 1.2 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 2.7 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 1.5 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 3.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 2.5 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 0.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.8 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.6 | 13.8 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 3.0 | 8.9 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 2.9 | 8.7 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 1.7 | 5.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 1.7 | 6.8 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 1.5 | 1.5 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 1.4 | 4.1 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 1.2 | 7.3 | GO:1990254 | keratin filament binding(GO:1990254) |
| 1.1 | 6.3 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.9 | 7.7 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.8 | 2.5 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.8 | 5.1 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.7 | 5.9 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.7 | 4.2 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.7 | 6.8 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.7 | 6.7 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.7 | 2.6 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.6 | 15.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.6 | 3.6 | GO:0051022 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.6 | 9.5 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.6 | 1.7 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.5 | 3.3 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) |
| 0.5 | 2.7 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.5 | 2.7 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.5 | 9.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.5 | 1.5 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.5 | 1.9 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.5 | 1.9 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.5 | 1.8 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.5 | 24.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.5 | 2.7 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.4 | 5.3 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.4 | 1.3 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 0.4 | 10.4 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.4 | 1.3 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.4 | 1.2 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.4 | 4.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.4 | 3.4 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.4 | 19.3 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.4 | 1.1 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.4 | 2.2 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.4 | 2.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.4 | 1.1 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.3 | 2.8 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.3 | 4.7 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.3 | 3.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.3 | 1.9 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 1.6 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.3 | 4.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.3 | 0.9 | GO:0051765 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 0.3 | 3.3 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.3 | 1.1 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.3 | 1.1 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.3 | 1.3 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 0.3 | 0.8 | GO:0031859 | platelet activating factor receptor binding(GO:0031859) |
| 0.3 | 0.8 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.3 | 4.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.2 | 1.4 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.2 | 6.2 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.2 | 5.3 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.2 | 0.9 | GO:0035473 | lipase binding(GO:0035473) |
| 0.2 | 1.1 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.2 | 15.2 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.2 | 3.8 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.2 | 2.1 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.2 | 3.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.2 | 6.5 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.2 | 5.2 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.2 | 0.6 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 0.7 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.2 | 2.0 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.2 | 1.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 4.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.2 | 5.0 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.2 | 0.6 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.2 | 0.6 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.1 | 4.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 1.0 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 39.7 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.1 | 2.3 | GO:0035613 | RNA stem-loop binding(GO:0035613) mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 1.5 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.1 | 9.2 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.1 | 0.3 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.1 | 1.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 0.8 | GO:0005329 | dopamine transmembrane transporter activity(GO:0005329) |
| 0.1 | 0.8 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 1.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 2.9 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 3.3 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.1 | 0.7 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 1.3 | GO:0032041 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 1.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 2.5 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
| 0.1 | 1.8 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.1 | 1.4 | GO:0031701 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 1.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 0.9 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 3.5 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.1 | 2.1 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.1 | 0.6 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
| 0.1 | 3.9 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 1.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 1.4 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 0.4 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 2.9 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
| 0.1 | 2.9 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 4.3 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.1 | 1.1 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 1.0 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.6 | GO:0009374 | biotin binding(GO:0009374) |
| 0.1 | 2.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 1.8 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 7.0 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.1 | 5.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 1.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 14.1 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 1.9 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.9 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.7 | GO:0004908 | interleukin-1 receptor activity(GO:0004908) |
| 0.0 | 1.7 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 24.8 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 5.6 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.6 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.6 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 0.8 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.0 | 0.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.2 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.0 | 6.6 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 1.9 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 1.7 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.4 | GO:0005536 | glucose binding(GO:0005536) |
| 0.0 | 16.6 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 10.1 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.0 | 0.8 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 0.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 23.3 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.4 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.4 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 2.8 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 0.2 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 1.4 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 26.9 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.4 | 6.8 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.3 | 15.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.2 | 18.1 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.2 | 6.0 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.2 | 2.8 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.2 | 4.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.2 | 5.0 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.2 | 3.4 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.2 | 3.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.2 | 8.5 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 4.2 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 7.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 2.4 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 4.2 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 1.4 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 6.7 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 17.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 1.2 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 3.1 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.1 | 3.3 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.1 | 3.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 3.4 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 2.7 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 3.6 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 3.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.1 | 2.1 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 2.9 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 3.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 2.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 0.3 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 2.0 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 1.1 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 5.1 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.6 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 1.4 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 1.0 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 2.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.1 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 10.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 5.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.7 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.2 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 5.2 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 0.8 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.3 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.4 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.4 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 23.3 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.8 | 0.8 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.4 | 14.1 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.4 | 7.9 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.4 | 15.2 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.3 | 4.1 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.3 | 10.4 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.3 | 7.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 5.9 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 5.3 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.2 | 4.3 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.2 | 13.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.2 | 2.3 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.2 | 1.3 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.2 | 4.1 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.2 | 4.6 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.2 | 3.6 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 4.2 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.1 | 3.4 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 3.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 2.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.9 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.1 | 2.7 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.1 | 0.8 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 5.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.2 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 10.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 1.3 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 4.3 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 3.5 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.1 | 2.3 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.1 | 6.3 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 6.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 1.2 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.1 | 0.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 2.1 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.1 | 2.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 1.3 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.1 | 3.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 6.4 | REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION | Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
| 0.1 | 8.9 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.0 | 1.4 | REACTOME FRS2 MEDIATED CASCADE | Genes involved in FRS2-mediated cascade |
| 0.0 | 0.8 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 1.6 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 2.7 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.8 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 2.4 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.8 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 1.4 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 1.3 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 5.7 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 1.8 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.3 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.0 | 1.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.6 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.7 | REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | Genes involved in NCAM signaling for neurite out-growth |
| 0.0 | 0.2 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
| 0.0 | 0.6 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |