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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for RXRA_NR2F6_NR2C2

Z-value: 1.34

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Transcription factors associated with RXRA_NR2F6_NR2C2

Gene Symbol Gene ID Gene Info
ENSG00000186350.8 retinoid X receptor alpha
ENSG00000160113.5 nuclear receptor subfamily 2 group F member 6
ENSG00000177463.11 nuclear receptor subfamily 2 group C member 2

Activity-expression correlation:

Activity profile of RXRA_NR2F6_NR2C2 motif

Sorted Z-values of RXRA_NR2F6_NR2C2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_132413739 30.51 ENST00000443358.2
pseudouridylate synthase 1
chr12_+_132413798 25.18 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
pseudouridylate synthase 1
chr12_+_132413765 22.84 ENST00000376649.3
ENST00000322060.5
pseudouridylate synthase 1
chr8_-_80942061 22.47 ENST00000519386.1
mitochondrial ribosomal protein S28
chr19_+_50919056 22.21 ENST00000599632.1
CTD-2545M3.6
chr6_+_24775153 19.93 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr12_+_96252706 19.53 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr3_-_119396193 19.40 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
COX17 cytochrome c oxidase copper chaperone
chr8_-_80942139 19.32 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr7_-_72936531 17.17 ENST00000339594.4
bromodomain adjacent to zinc finger domain, 1B
chr17_-_4852332 16.12 ENST00000572383.1
profilin 1
chr11_-_66206260 15.98 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
mitochondrial ribosomal protein L11
chr6_+_33172407 14.76 ENST00000374662.3
hydroxysteroid (17-beta) dehydrogenase 8
chr2_+_120125245 14.52 ENST00000393103.2
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr4_-_7069760 13.83 ENST00000264954.4
GrpE-like 1, mitochondrial (E. coli)
chr8_-_80942467 13.00 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
mitochondrial ribosomal protein S28
chr2_-_219134343 12.76 ENST00000447885.1
ENST00000420660.1
angio-associated, migratory cell protein
chr17_-_4852243 12.65 ENST00000225655.5
profilin 1
chr16_+_30075463 12.53 ENST00000562168.1
ENST00000569545.1
aldolase A, fructose-bisphosphate
chr1_+_154947148 12.20 ENST00000368436.1
ENST00000308987.5
CDC28 protein kinase regulatory subunit 1B
chr1_-_193075180 12.09 ENST00000367440.3
glutaredoxin 2
chr2_-_207024134 12.03 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr16_+_30075595 12.02 ENST00000563060.2
aldolase A, fructose-bisphosphate
chr1_+_154947126 11.77 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chr2_+_200820269 11.70 ENST00000392290.1
chromosome 2 open reading frame 47
chr16_+_30075783 11.28 ENST00000412304.2
aldolase A, fructose-bisphosphate
chr2_+_198365122 11.22 ENST00000604458.1
HSPE1-MOB4 readthrough
chr5_+_1801503 10.94 ENST00000274137.5
ENST00000469176.1
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr1_-_43855444 10.86 ENST00000372455.4
mediator complex subunit 8
chr2_-_207024233 10.71 ENST00000423725.1
ENST00000233190.6
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr18_-_54318353 10.70 ENST00000590954.1
ENST00000540155.1
thioredoxin-like 1
chr19_-_59023348 10.65 ENST00000601355.1
ENST00000263093.2
solute carrier family 27 (fatty acid transporter), member 5
chr1_+_65613340 10.47 ENST00000546702.1
adenylate kinase 4
chr2_+_86426478 10.45 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr8_+_145582633 10.21 ENST00000540505.1
solute carrier family 52 (riboflavin transporter), member 2
chrX_-_1511617 10.04 ENST00000381401.5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr19_-_17356697 9.91 ENST00000291442.3
nuclear receptor subfamily 2, group F, member 6
chr1_+_165864800 9.37 ENST00000469256.2
uridine-cytidine kinase 2
chr1_+_165864821 9.30 ENST00000470820.1
uridine-cytidine kinase 2
chr2_+_198365095 9.08 ENST00000409468.1
heat shock 10kDa protein 1
chr16_+_2255841 8.85 ENST00000301725.7
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr16_+_2255710 8.61 ENST00000397124.1
ENST00000565250.1
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr2_+_178257372 8.49 ENST00000264167.4
ENST00000409888.1
alkylglycerone phosphate synthase
chr22_+_30163340 8.48 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr7_-_65447192 8.44 ENST00000421103.1
ENST00000345660.6
ENST00000304895.4
glucuronidase, beta
chr1_-_6420737 8.41 ENST00000541130.1
ENST00000377845.3
acyl-CoA thioesterase 7
chr11_-_73687997 8.35 ENST00000545212.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr2_-_219134822 8.03 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr22_-_19165917 7.55 ENST00000451283.1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr5_+_271733 7.46 ENST00000264933.4
programmed cell death 6
chr19_-_2328572 7.35 ENST00000252622.10
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_211848899 7.27 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NIMA-related kinase 2
chrY_-_1461617 7.08 ENSTR0000381401.5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr12_-_7079805 6.79 ENST00000536316.2
ENST00000542912.1
ENST00000440277.1
ENST00000545167.1
ENST00000546111.1
ENST00000399433.2
ENST00000535923.1
prohibitin 2
chr6_-_33282163 6.55 ENST00000434618.2
ENST00000456592.2
TAP binding protein (tapasin)
chr1_-_161193349 6.47 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr5_+_271752 6.42 ENST00000505221.1
ENST00000509581.1
ENST00000507528.1
programmed cell death 6
chr16_-_4401258 6.39 ENST00000577031.1
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr11_+_64073699 5.91 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr19_-_51869592 5.84 ENST00000596253.1
ENST00000309244.4
electron-transfer-flavoprotein, beta polypeptide
chr15_+_43985084 5.81 ENST00000434505.1
ENST00000411750.1
creatine kinase, mitochondrial 1A
chr3_-_113465065 5.81 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_-_156722015 5.75 ENST00000368209.5
hepatoma-derived growth factor
chr2_+_219283815 5.72 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
villin 1
chr11_+_67798363 5.70 ENST00000525628.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr4_+_174089904 5.69 ENST00000265000.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr16_-_4401284 5.60 ENST00000318059.3
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr17_+_7123125 5.54 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
acyl-CoA dehydrogenase, very long chain
chr2_+_159313452 5.53 ENST00000389757.3
ENST00000389759.3
plakophilin 4
chr11_+_85339623 5.53 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
transmembrane protein 126B
chr6_-_33385854 5.50 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr22_-_37415475 5.48 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
thiosulfate sulfurtransferase (rhodanese)
chr1_-_156721389 5.38 ENST00000537739.1
hepatoma-derived growth factor
chr2_+_10442993 5.34 ENST00000423674.1
ENST00000307845.3
hippocalcin-like 1
chr1_+_110527308 5.31 ENST00000369799.5
adenosylhomocysteinase-like 1
chr1_-_8938736 5.28 ENST00000234590.4
enolase 1, (alpha)
chr15_+_43885252 5.20 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
creatine kinase, mitochondrial 1B
chr12_+_6977258 5.20 ENST00000488464.2
ENST00000535434.1
ENST00000493987.1
triosephosphate isomerase 1
chr1_-_155880672 5.14 ENST00000609492.1
ENST00000368322.3
Ras-like without CAAX 1
chr3_+_52232102 5.14 ENST00000469224.1
ENST00000394965.2
ENST00000310271.2
ENST00000484952.1
aminolevulinate, delta-, synthase 1
chr15_-_76603727 5.11 ENST00000560595.1
ENST00000433983.2
ENST00000559386.1
ENST00000559602.1
ENST00000560726.1
ENST00000557943.1
electron-transfer-flavoprotein, alpha polypeptide
chr7_-_102232891 5.04 ENST00000514917.2
RP11-514P8.7
chr1_-_156721502 5.02 ENST00000357325.5
hepatoma-derived growth factor
chr22_-_24316648 4.99 ENST00000403754.3
ENST00000430101.2
ENST00000398344.4
D-dopachrome tautomerase
chr7_-_74489609 4.97 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
Williams-Beuren syndrome chromosome region 16
chr8_-_145331153 4.92 ENST00000377412.4
KM-PA-2 protein; Uncharacterized protein
chr22_+_24309089 4.78 ENST00000215770.5
D-dopachrome tautomerase-like
chr2_-_74607390 4.75 ENST00000413111.1
ENST00000409567.3
ENST00000454119.1
ENST00000361874.3
ENST00000394003.3
dynactin 1
chr3_-_100120223 4.72 ENST00000284320.5
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr11_+_86013253 4.72 ENST00000533986.1
ENST00000278483.3
chromosome 11 open reading frame 73
chr12_+_7079944 4.71 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr11_+_118443098 4.70 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
archain 1
chr6_-_33385655 4.61 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chrX_-_153191708 4.60 ENST00000393721.1
ENST00000370028.3
Rho GTPase activating protein 4
chrX_+_154611749 4.55 ENST00000369505.3
coagulation factor VIII-associated 2
chr6_+_13615554 4.55 ENST00000451315.2
nucleolar protein 7, 27kDa
chrX_-_152760934 4.55 ENST00000370210.1
ENST00000421080.2
HAUS augmin-like complex, subunit 7
chr19_-_10687907 4.54 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr11_-_64013663 4.53 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_80017856 4.43 ENST00000577574.1
dihydrouridine synthase 1-like (S. cerevisiae)
chr10_-_96829246 4.39 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr1_-_36930012 4.38 ENST00000373116.5
mitochondrial ribosomal protein S15
chr11_-_6640585 4.34 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
tripeptidyl peptidase I
chr6_+_143772060 4.31 ENST00000367591.4
peroxisomal biogenesis factor 3
chr5_+_162864575 4.26 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr17_-_61920280 4.24 ENST00000448276.2
ENST00000577990.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr6_-_31926629 4.23 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
negative elongation factor complex member E
chr13_+_50656307 4.23 ENST00000378180.4
deleted in lymphocytic leukemia 1 (non-protein coding)
chr6_-_33385870 4.18 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr11_+_46383121 4.13 ENST00000454345.1
diacylglycerol kinase, zeta
chr17_+_37894179 4.10 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
growth factor receptor-bound protein 7
chr14_-_75643296 4.07 ENST00000303575.4
transmembrane emp24-like trafficking protein 10 (yeast)
chr3_-_197300194 4.06 ENST00000358186.2
ENST00000431056.1
3-hydroxybutyrate dehydrogenase, type 1
chr11_+_67798090 4.04 ENST00000313468.5
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chrX_-_153285251 3.95 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr16_+_4475806 3.88 ENST00000262375.6
ENST00000355296.4
ENST00000431375.2
ENST00000574895.1
DnaJ (Hsp40) homolog, subfamily A, member 3
chr22_+_20105012 3.87 ENST00000331821.3
ENST00000411892.1
RAN binding protein 1
chr1_+_113161778 3.81 ENST00000263168.3
capping protein (actin filament) muscle Z-line, alpha 1
chr6_-_33385823 3.81 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr17_+_46970178 3.74 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_+_46970134 3.69 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chrX_-_153285395 3.68 ENST00000369980.3
interleukin-1 receptor-associated kinase 1
chr1_+_26869597 3.68 ENST00000530003.1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr6_-_33385902 3.67 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr12_-_56694142 3.66 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chr17_+_42427826 3.62 ENST00000586443.1
granulin
chr16_-_67970990 3.60 ENST00000358514.4
proteasome (prosome, macropain) subunit, beta type, 10
chr6_-_31704282 3.55 ENST00000375784.3
ENST00000375779.2
chloride intracellular channel 1
chr7_-_107204918 3.55 ENST00000297135.3
component of oligomeric golgi complex 5
chr5_-_68665296 3.54 ENST00000512152.1
ENST00000503245.1
ENST00000512561.1
ENST00000380822.4
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr6_+_88299833 3.52 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
origin recognition complex, subunit 3
chr17_-_79895097 3.50 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
pyrroline-5-carboxylate reductase 1
chr17_+_46970127 3.48 ENST00000355938.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr1_+_38478378 3.37 ENST00000373014.4
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr4_-_103266626 3.36 ENST00000356736.4
solute carrier family 39 (zinc transporter), member 8
chr11_+_67798114 3.35 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr19_+_11546093 3.34 ENST00000591462.1
protein kinase C substrate 80K-H
chr17_-_79894651 3.34 ENST00000584848.1
ENST00000577756.1
ENST00000329875.8
pyrroline-5-carboxylate reductase 1
chr17_-_27503770 3.32 ENST00000533112.1
myosin XVIIIA
chr8_+_22224811 3.31 ENST00000381237.1
solute carrier family 39 (zinc transporter), member 14
chr21_-_45196326 3.30 ENST00000291568.5
cystatin B (stefin B)
chr19_+_535835 3.30 ENST00000607527.1
ENST00000606065.1
cell division cycle 34
chr5_-_68665815 3.29 ENST00000380818.3
ENST00000328663.4
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr17_-_42144949 3.26 ENST00000591247.1
LSM12 homolog (S. cerevisiae)
chr11_-_57298187 3.25 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr8_+_22224760 3.23 ENST00000359741.5
ENST00000520644.1
ENST00000240095.6
solute carrier family 39 (zinc transporter), member 14
chr19_+_10362882 3.18 ENST00000393733.2
ENST00000588502.1
mitochondrial ribosomal protein L4
chr1_-_155271213 3.17 ENST00000342741.4
pyruvate kinase, liver and RBC
chr1_+_145727681 3.14 ENST00000417171.1
ENST00000451928.2
PDZ domain containing 1
chr22_+_37415676 3.14 ENST00000401419.3
mercaptopyruvate sulfurtransferase
chr17_+_41150793 3.09 ENST00000586277.1
ribosomal protein L27
chr16_-_47007545 3.08 ENST00000317089.5
DnaJ (Hsp40) homolog, subfamily A, member 2
chr19_+_10197463 3.08 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr15_-_82555000 3.05 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
elongation factor Tu GTP binding domain containing 1
chr22_+_44351419 3.03 ENST00000396202.3
SAMM50 sorting and assembly machinery component
chr3_-_47517302 3.02 ENST00000441517.2
ENST00000545718.1
SREBF chaperone
chr1_-_155270770 3.00 ENST00000392414.3
pyruvate kinase, liver and RBC
chr22_+_37415728 3.00 ENST00000404802.3
mercaptopyruvate sulfurtransferase
chr20_-_48729670 3.00 ENST00000371657.5
ubiquitin-conjugating enzyme E2 variant 1
chr22_+_37415700 2.98 ENST00000397129.1
mercaptopyruvate sulfurtransferase
chr11_+_64001962 2.98 ENST00000309422.2
vascular endothelial growth factor B
chr1_+_151129135 2.96 ENST00000602841.1
sodium channel modifier 1
chr22_+_37415776 2.95 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
mercaptopyruvate sulfurtransferase
chr17_+_1646130 2.93 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chrX_-_70474910 2.91 ENST00000373988.1
ENST00000373998.1
zinc finger, MYM-type 3
chr17_+_41150479 2.88 ENST00000589913.1
ribosomal protein L27
chr12_-_6960407 2.85 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
cell division cycle associated 3
chr17_+_41150290 2.80 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chrX_-_15511438 2.78 ENST00000380420.5
pirin (iron-binding nuclear protein)
chr12_+_52463751 2.77 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
chromosome 12 open reading frame 44
chr18_-_47340297 2.75 ENST00000586485.1
ENST00000587994.1
ENST00000586100.1
ENST00000285093.10
acetyl-CoA acyltransferase 2
chr22_+_44351301 2.75 ENST00000350028.4
SAMM50 sorting and assembly machinery component
chr2_+_28113583 2.71 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr5_-_68665469 2.70 ENST00000217893.5
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr11_+_71938925 2.70 ENST00000538751.1
inositol polyphosphate phosphatase-like 1
chr19_+_11546440 2.69 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
protein kinase C substrate 80K-H
chr12_+_67663056 2.67 ENST00000545606.1
cullin-associated and neddylation-dissociated 1
chr17_+_37821593 2.64 ENST00000578283.1
titin-cap
chr5_-_68665084 2.63 ENST00000509462.1
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr1_-_173886491 2.63 ENST00000367698.3
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr11_+_64002292 2.62 ENST00000426086.2
vascular endothelial growth factor B
chr22_+_20105259 2.56 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
RAN binding protein 1
chr2_+_234621551 2.53 ENST00000608381.1
ENST00000373414.3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr2_+_217498105 2.52 ENST00000233809.4
insulin-like growth factor binding protein 2, 36kDa
chr1_-_109968973 2.51 ENST00000271308.4
ENST00000538610.1
proteasome (prosome, macropain) subunit, alpha type, 5
chr3_+_113465866 2.50 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr15_+_43985725 2.39 ENST00000413453.2
creatine kinase, mitochondrial 1A
chr19_-_51466681 2.37 ENST00000456750.2
kallikrein-related peptidase 6
chr3_-_11610255 2.36 ENST00000424529.2
vestigial like 4 (Drosophila)
chr19_+_45394477 2.36 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr19_-_8008533 2.36 ENST00000597926.1
translocase of inner mitochondrial membrane 44 homolog (yeast)
chr1_+_110163202 2.34 ENST00000531203.1
ENST00000256578.3
adenosine monophosphate deaminase 2
chr17_+_75446819 2.33 ENST00000541152.2
ENST00000591704.1
septin 9
chr22_+_23077065 2.32 ENST00000390310.2
immunoglobulin lambda variable 2-18
chrX_-_41782249 2.27 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr17_+_7155556 2.24 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
elongator acetyltransferase complex subunit 5
chr5_+_156712372 2.23 ENST00000541131.1
cytoplasmic FMR1 interacting protein 2
chr14_-_25519095 2.21 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
syntaxin binding protein 6 (amisyn)
chr19_+_44100632 2.21 ENST00000533118.1
zinc finger protein 576
chr11_+_394196 2.21 ENST00000331563.2
ENST00000531857.1
plakophilin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRA_NR2F6_NR2C2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
26.2 78.5 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
5.7 17.1 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
4.7 18.7 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
3.5 3.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.5 17.5 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
3.4 10.3 GO:2000909 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
3.3 19.9 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
2.9 28.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
2.8 8.5 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.6 10.2 GO:0032218 riboflavin transport(GO:0032218)
2.4 14.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
2.3 13.9 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
2.1 8.4 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
2.0 30.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
2.0 35.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.9 7.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.7 5.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.5 10.6 GO:0006642 triglyceride mobilization(GO:0006642)
1.5 7.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.3 12.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.2 1.2 GO:0009822 alkaloid catabolic process(GO:0009822)
1.2 12.1 GO:0042262 DNA protection(GO:0042262)
1.2 88.8 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
1.2 14.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.2 4.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.1 11.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.1 5.7 GO:1902896 terminal web assembly(GO:1902896)
1.1 6.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.1 3.3 GO:1903028 positive regulation of opsonization(GO:1903028)
1.1 8.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
1.0 4.1 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
1.0 6.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.0 4.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.0 6.8 GO:0033600 positive regulation of exit from mitosis(GO:0031536) negative regulation of mammary gland epithelial cell proliferation(GO:0033600) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.0 5.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.9 12.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.9 5.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.9 14.5 GO:0018345 protein palmitoylation(GO:0018345)
0.9 2.6 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.8 8.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8 4.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.8 4.7 GO:0006789 bilirubin conjugation(GO:0006789)
0.8 7.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.8 59.1 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.8 11.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.8 5.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.7 8.2 GO:0006600 creatine metabolic process(GO:0006600)
0.7 4.4 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.7 5.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.7 3.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.6 6.4 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.6 4.4 GO:0002933 lipid hydroxylation(GO:0002933)
0.6 0.6 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.6 3.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.6 4.8 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.6 4.7 GO:0070475 rRNA base methylation(GO:0070475)
0.6 19.5 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.6 0.6 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.5 17.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.5 1.6 GO:1990641 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.5 3.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.5 1.6 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.5 4.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.5 6.6 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.5 24.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.5 5.0 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.5 1.4 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.5 3.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.5 1.4 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.4 8.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.4 2.2 GO:0002159 desmosome assembly(GO:0002159)
0.4 3.9 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.4 2.9 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.4 3.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 2.5 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.4 2.0 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.4 10.1 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.4 1.2 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.4 5.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.4 7.6 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.4 10.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 8.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 2.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 0.9 GO:2000395 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.3 1.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 4.2 GO:1900364 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) negative regulation of mRNA polyadenylation(GO:1900364)
0.3 0.6 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.3 0.9 GO:0050894 determination of affect(GO:0050894)
0.3 0.6 GO:0097327 response to antineoplastic agent(GO:0097327)
0.3 3.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.3 0.8 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 2.7 GO:0010265 SCF complex assembly(GO:0010265)
0.3 7.6 GO:0006491 N-glycan processing(GO:0006491)
0.3 20.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 1.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 0.9 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.2 1.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 2.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 0.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2 0.6 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 3.5 GO:0034063 stress granule assembly(GO:0034063)
0.2 1.8 GO:0070836 caveola assembly(GO:0070836)
0.2 3.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 0.8 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.2 0.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 0.9 GO:0072719 cellular response to cisplatin(GO:0072719)
0.2 4.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 4.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 3.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 16.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 1.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 2.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 0.7 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 1.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 1.6 GO:0032264 IMP salvage(GO:0032264)
0.2 2.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 2.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 2.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 5.0 GO:0042438 melanin biosynthetic process(GO:0042438)
0.2 1.1 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body biosynthetic process(GO:0046951) ketone body metabolic process(GO:1902224)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.6 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.1 4.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 3.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.4 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 4.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.4 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 0.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 3.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 3.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 5.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 1.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 6.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 3.1 GO:0042026 protein refolding(GO:0042026)
0.1 3.1 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.1 1.6 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.2 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 1.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 4.8 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.4 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 5.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 1.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 2.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.3 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 2.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 1.5 GO:0006907 pinocytosis(GO:0006907)
0.1 2.5 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.9 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.6 GO:0001878 response to yeast(GO:0001878)
0.1 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.1 7.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 0.5 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 1.7 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 5.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 4.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 1.3 GO:0030252 growth hormone secretion(GO:0030252)
0.1 0.5 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 1.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 8.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.9 GO:0046519 sphingoid metabolic process(GO:0046519)
0.1 1.0 GO:0019184 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.1 3.6 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 2.8 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 1.0 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.1 0.8 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.8 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 4.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 1.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0007631 feeding behavior(GO:0007631)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 2.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.7 GO:0070873 regulation of polysaccharide metabolic process(GO:0032881) regulation of glycogen metabolic process(GO:0070873)
0.0 0.6 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 1.4 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 13.0 GO:0016567 protein ubiquitination(GO:0016567)
0.0 2.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 3.9 GO:0010038 response to metal ion(GO:0010038)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 25.8 GO:0001405 presequence translocase-associated import motor(GO:0001405)
4.5 22.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
2.5 20.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
2.4 19.5 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
2.2 18.0 GO:0031931 TORC1 complex(GO:0031931)
2.2 59.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.5 7.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.5 12.2 GO:0070761 pre-snoRNP complex(GO:0070761)
1.2 3.5 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.1 6.4 GO:0042825 TAP complex(GO:0042825)
1.1 7.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.0 5.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.9 5.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.8 4.2 GO:0032021 NELF complex(GO:0032021)
0.8 5.8 GO:0031415 NatA complex(GO:0031415)
0.8 29.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.8 8.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.7 8.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.7 16.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.7 20.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.6 10.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.6 10.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6 1.8 GO:0071159 NF-kappaB complex(GO:0071159)
0.6 5.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.6 29.5 GO:0031430 M band(GO:0031430)
0.5 3.8 GO:0071203 WASH complex(GO:0071203)
0.5 14.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 4.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 4.5 GO:0070652 HAUS complex(GO:0070652)
0.5 3.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 2.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 24.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.4 25.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 4.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 20.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 145.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.3 4.4 GO:0017119 Golgi transport complex(GO:0017119)
0.3 4.8 GO:0005869 dynactin complex(GO:0005869)
0.3 11.6 GO:0016592 mediator complex(GO:0016592)
0.3 0.8 GO:0033565 ESCRT-0 complex(GO:0033565)
0.3 1.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 4.3 GO:0005652 nuclear lamina(GO:0005652)
0.3 5.2 GO:0032433 filopodium tip(GO:0032433)
0.2 7.7 GO:0030057 desmosome(GO:0030057)
0.2 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 2.9 GO:0005577 fibrinogen complex(GO:0005577)
0.2 10.1 GO:0009925 basal plasma membrane(GO:0009925)
0.2 2.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.6 GO:0045179 apical cortex(GO:0045179)
0.2 0.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 2.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 0.9 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.2 4.0 GO:0000145 exocyst(GO:0000145)
0.2 3.0 GO:0031105 septin complex(GO:0031105)
0.2 2.3 GO:0070578 RISC-loading complex(GO:0070578)
0.2 8.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 4.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 12.2 GO:0000502 proteasome complex(GO:0000502)
0.2 3.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 32.0 GO:0072562 blood microparticle(GO:0072562)
0.2 3.8 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 4.7 GO:0032040 small-subunit processome(GO:0032040)
0.1 4.7 GO:0030426 growth cone(GO:0030426)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 29.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 2.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 11.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 10.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.1 6.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 8.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.8 GO:0016600 flotillin complex(GO:0016600)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 22.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 4.5 GO:0016459 myosin complex(GO:0016459)
0.1 3.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 3.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 13.1 GO:0030027 lamellipodium(GO:0030027)
0.0 3.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 2.1 GO:0030018 Z disc(GO:0030018)
0.0 1.7 GO:0032994 protein-lipid complex(GO:0032994)
0.0 1.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 3.4 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 1.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
26.2 78.5 GO:0004730 pseudouridylate synthase activity(GO:0004730)
4.3 17.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
3.6 14.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
3.6 42.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.4 24.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.3 35.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
3.2 19.4 GO:0016531 copper chaperone activity(GO:0016531)
3.0 12.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
3.0 14.8 GO:0070404 NADH binding(GO:0070404)
2.7 5.5 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
2.7 10.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.7 18.7 GO:0004849 uridine kinase activity(GO:0004849)
2.6 10.2 GO:0032217 riboflavin transporter activity(GO:0032217)
2.4 12.1 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
2.3 22.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
2.1 8.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.9 7.5 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.7 5.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.7 6.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.6 6.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
1.5 6.2 GO:0004743 pyruvate kinase activity(GO:0004743)
1.5 10.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.4 5.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.4 4.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.2 5.0 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
1.2 22.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.2 8.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.2 7.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.1 7.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.1 7.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.0 8.2 GO:0004111 creatine kinase activity(GO:0004111)
0.9 4.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.9 5.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.9 5.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.9 4.4 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.9 12.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.8 5.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.8 3.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.8 12.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.7 4.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.7 5.7 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.7 9.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 12.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.6 9.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.6 12.7 GO:0043495 protein anchor(GO:0043495)
0.6 2.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.5 17.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.5 14.3 GO:0035173 histone kinase activity(GO:0035173)
0.5 2.6 GO:0051373 FATZ binding(GO:0051373)
0.5 25.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 1.6 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5 5.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.5 1.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 5.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.4 10.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 0.4 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.4 7.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.4 5.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 3.6 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.4 1.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.4 8.5 GO:0071949 FAD binding(GO:0071949)
0.3 4.7 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.3 0.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.3 2.8 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.3 2.7 GO:0035877 death effector domain binding(GO:0035877)
0.3 0.9 GO:0031877 somatostatin receptor binding(GO:0031877)
0.3 4.5 GO:0031996 thioesterase binding(GO:0031996)
0.3 1.3 GO:0004386 helicase activity(GO:0004386)
0.3 2.4 GO:0015288 porin activity(GO:0015288)
0.3 4.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.7 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 17.8 GO:0005507 copper ion binding(GO:0005507)
0.2 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 2.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 4.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 2.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 32.7 GO:0051082 unfolded protein binding(GO:0051082)
0.2 15.0 GO:0019843 rRNA binding(GO:0019843)
0.2 1.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 3.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.8 GO:0032810 sterol response element binding(GO:0032810)
0.2 6.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 2.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 1.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 17.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 2.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 1.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 4.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 26.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 2.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 3.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 3.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 4.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 7.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 4.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 10.9 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 2.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 2.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 2.8 GO:0001848 complement binding(GO:0001848)
0.1 4.6 GO:0070888 E-box binding(GO:0070888)
0.1 1.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 3.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 5.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 2.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.3 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:0005522 profilin binding(GO:0005522)
0.1 0.1 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.2 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 6.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 5.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.7 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.1 GO:0043531 ADP binding(GO:0043531)
0.0 5.9 GO:0000149 SNARE binding(GO:0000149)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 5.1 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 36.6 GO:0003723 RNA binding(GO:0003723)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 3.1 GO:0016829 lyase activity(GO:0016829)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 5.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.9 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0015923 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.0 1.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 41.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.4 31.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.4 28.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 5.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 9.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.3 17.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 12.2 PID MYC PATHWAY C-MYC pathway
0.3 14.6 PID IL1 PATHWAY IL1-mediated signaling events
0.3 15.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 10.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 4.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 3.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 6.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 95.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.2 23.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
1.2 19.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.1 10.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.0 51.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.9 9.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.8 17.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.5 18.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.5 4.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.4 7.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.4 8.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 24.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.4 36.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 6.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 8.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 29.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.4 19.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 7.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 7.4 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.3 7.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.3 2.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.3 7.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 7.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 6.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 7.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 9.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 4.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 7.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 0.7 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.2 12.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 16.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 3.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 0.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 4.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 6.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 2.9 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 7.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 3.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 7.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 2.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 7.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 8.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 6.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 6.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification