Project

averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for SHOX2_HOXC5

Z-value: 1.60

Motif logo

Transcription factors associated with SHOX2_HOXC5

Gene Symbol Gene ID Gene Info
ENSG00000168779.15 short stature homeobox 2
ENSG00000172789.3 homeobox C5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SHOX2hg19_v2_chr3_-_157824292_157824334-0.409.7e-10Click!
HOXC5hg19_v2_chr12_+_54426637_54426637-0.072.8e-01Click!

Activity profile of SHOX2_HOXC5 motif

Sorted Z-values of SHOX2_HOXC5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89292422 31.06 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr6_-_32557610 30.36 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr2_+_90108504 29.71 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_90077680 29.35 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr1_-_153518270 24.44 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr2_-_89385283 23.93 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr2_-_89340242 23.52 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr2_+_90198535 23.50 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr2_-_89247338 22.63 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr11_+_35201826 22.53 ENST00000531873.1
CD44 molecule (Indian blood group)
chr15_-_20193370 22.42 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_-_89327228 20.67 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr7_-_87856280 20.57 ENST00000490437.1
ENST00000431660.1
sorcin
chr7_+_115862858 20.43 ENST00000393481.2
testis derived transcript (3 LIM domains)
chr2_-_89513402 20.23 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr2_+_87565634 20.20 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr2_+_90153696 20.09 ENST00000417279.2
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr2_+_90139056 19.94 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr2_-_90538397 19.31 ENST00000443397.3
Uncharacterized protein
chr2_+_90273679 19.03 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr7_-_87856303 18.56 ENST00000394641.3
sorcin
chr11_+_5710919 18.47 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr11_-_104817919 18.26 ENST00000533252.1
caspase 4, apoptosis-related cysteine peptidase
chr2_+_90248739 17.62 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr6_+_26365443 16.92 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr11_-_104972158 16.83 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr17_+_48823975 16.66 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr12_-_10022735 16.62 ENST00000228438.2
C-type lectin domain family 2, member B
chr7_+_141438118 16.45 ENST00000265304.6
ENST00000498107.1
ENST00000467681.1
ENST00000465582.1
ENST00000463093.1
single-stranded DNA binding protein 1, mitochondrial
chr3_+_37035289 16.28 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
mutL homolog 1
chr14_-_106552755 16.22 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr2_+_68961934 15.87 ENST00000409202.3
Rho GTPase activating protein 25
chr14_-_107049312 15.87 ENST00000390627.2
immunoglobulin heavy variable 3-53
chr7_-_139763521 15.82 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr2_+_68961905 15.66 ENST00000295381.3
Rho GTPase activating protein 25
chr4_+_113568207 15.05 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr1_-_89357179 14.40 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chr4_-_103749179 14.38 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr11_-_33913708 14.11 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr2_-_17981462 13.82 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr16_+_12059091 13.32 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr6_+_31802364 13.19 ENST00000375640.3
ENST00000375641.2
chromosome 6 open reading frame 48
chr4_-_103749205 13.14 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr2_-_89521942 12.68 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr5_-_10761206 12.64 ENST00000432074.2
ENST00000230895.6
death-associated protein
chr2_+_219110149 12.61 ENST00000456575.1
actin related protein 2/3 complex, subunit 2, 34kDa
chrX_-_100872911 12.31 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
armadillo repeat containing, X-linked 6
chr11_-_104827425 12.29 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr6_+_42584847 12.22 ENST00000372883.3
ubiquitin protein ligase E3 component n-recognin 2
chr2_-_89417335 12.15 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr7_-_102184083 12.05 ENST00000379357.5
polymerase (RNA) II (DNA directed) polypeptide J3
chr6_+_32407619 11.82 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr14_+_52456327 11.82 ENST00000556760.1
chromosome 14 open reading frame 166
chr2_-_89568263 11.65 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr2_+_89952792 11.63 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr2_+_90211643 11.53 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr6_+_139456226 11.39 ENST00000367658.2
headcase homolog (Drosophila)
chr5_-_176433350 11.11 ENST00000377227.4
ENST00000377219.2
ubiquitin interaction motif containing 1
chr2_-_89160770 11.01 ENST00000390240.2
immunoglobulin kappa joining 3
chr3_+_138340049 10.88 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr11_-_104905840 10.87 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr1_+_220267429 10.72 ENST00000366922.1
ENST00000302637.5
isoleucyl-tRNA synthetase 2, mitochondrial
chr19_-_14945933 10.70 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr14_-_106668095 10.58 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr6_+_31802685 10.56 ENST00000375639.2
ENST00000375638.3
ENST00000375635.2
ENST00000375642.2
ENST00000395789.1
chromosome 6 open reading frame 48
chr1_-_160681593 10.30 ENST00000368045.3
ENST00000368046.3
CD48 molecule
chr15_+_64680003 10.17 ENST00000261884.3
thyroid hormone receptor interactor 4
chr10_+_122610687 10.15 ENST00000263461.6
WD repeat domain 11
chr2_-_176046391 10.02 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr20_-_33735070 9.87 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr8_-_101718991 9.81 ENST00000517990.1
poly(A) binding protein, cytoplasmic 1
chr22_+_21996549 9.80 ENST00000248958.4
stromal cell-derived factor 2-like 1
chr12_-_15114603 9.70 ENST00000228945.4
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_158345462 9.67 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr17_+_66511540 9.58 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_-_197115818 9.51 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr6_+_26104104 9.47 ENST00000377803.2
histone cluster 1, H4c
chr6_-_41909561 9.39 ENST00000372991.4
cyclin D3
chr18_-_47018897 9.25 ENST00000418495.1
ribosomal protein L17
chr18_-_47018869 9.20 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr14_-_106926724 9.17 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr19_-_39826639 8.81 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr14_+_35591928 8.80 ENST00000605870.1
ENST00000557404.3
KIAA0391
chr7_+_120591170 8.65 ENST00000431467.1
inhibitor of growth family, member 3
chr15_+_58430567 8.61 ENST00000536493.1
aquaporin 9
chr19_+_50016610 8.53 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr16_+_32077386 8.50 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr21_-_15918618 8.43 ENST00000400564.1
ENST00000400566.1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_+_113558612 8.35 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr8_-_90996837 8.31 ENST00000519426.1
ENST00000265433.3
nibrin
chr1_-_24306835 8.18 ENST00000484146.2
serine/arginine-rich splicing factor 10
chr3_-_141719195 8.05 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr16_+_12059050 8.01 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr17_+_7155819 7.98 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr3_-_141747950 7.97 ENST00000497579.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_-_23426337 7.94 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr2_-_238323007 7.92 ENST00000295550.4
collagen, type VI, alpha 3
chr11_+_125462690 7.90 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr5_-_81574160 7.89 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
ribosomal protein S23
chr19_-_17516449 7.86 ENST00000252593.6
bone marrow stromal cell antigen 2
chr2_+_86333301 7.84 ENST00000254630.7
pentatricopeptide repeat domain 3
chr14_-_23426322 7.80 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr2_-_89597542 7.64 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr17_+_41150290 7.63 ENST00000589037.1
ENST00000253788.5
ribosomal protein L27
chr1_-_1709845 7.60 ENST00000341426.5
ENST00000344463.4
NAD kinase
chr1_-_150738261 7.60 ENST00000448301.2
ENST00000368985.3
cathepsin S
chr2_-_89278535 7.60 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr4_+_113558272 7.58 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
La ribonucleoprotein domain family, member 7
chr19_+_50016411 7.57 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr17_+_48823896 7.56 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr12_-_102455846 7.52 ENST00000545679.1
coiled-coil domain containing 53
chr19_+_23945768 7.50 ENST00000486528.1
ENST00000496398.1
ribosomal protein SA pseudogene 58
chr19_+_48248779 7.50 ENST00000246802.5
glioma tumor suppressor candidate region gene 2
chr8_-_109260897 7.40 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr14_-_23426270 7.39 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr4_-_47465666 7.37 ENST00000381571.4
COMM domain containing 8
chr3_-_30936153 7.34 ENST00000454381.3
ENST00000282538.5
glutamate decarboxylase-like 1
chr6_-_109702885 7.32 ENST00000504373.1
CD164 molecule, sialomucin
chr1_-_1710229 7.26 ENST00000341991.3
NAD kinase
chr16_+_1359511 7.22 ENST00000397514.3
ENST00000397515.2
ENST00000567383.1
ENST00000403747.2
ENST00000566587.1
ubiquitin-conjugating enzyme E2I
chr13_+_37581115 7.22 ENST00000481013.1
exosome component 8
chr6_+_26440700 7.22 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr2_+_187371440 7.21 ENST00000445547.1
zinc finger CCCH-type containing 15
chr14_-_106573756 7.20 ENST00000390601.2
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr12_+_75874460 7.09 ENST00000266659.3
GLI pathogenesis-related 1
chr18_-_47018769 7.06 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chrX_-_122756660 7.06 ENST00000441692.1
THO complex 2
chr2_+_89901292 7.02 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr4_-_83812248 6.99 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31 homolog A (S. cerevisiae)
chr3_+_138340067 6.93 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr16_-_58585513 6.90 ENST00000245138.4
ENST00000567285.1
CCR4-NOT transcription complex, subunit 1
chr18_-_51751132 6.86 ENST00000256429.3
methyl-CpG binding domain protein 2
chr3_+_148709128 6.84 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
glycogenin 1
chr1_-_205091115 6.84 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr12_-_31479045 6.84 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr6_+_63921399 6.83 ENST00000356170.3
FK506 binding protein 1C
chr5_+_177631523 6.78 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
heterogeneous nuclear ribonucleoprotein A/B
chr3_-_16524357 6.78 ENST00000432519.1
raftlin, lipid raft linker 1
chr1_+_158801095 6.78 ENST00000368141.4
myeloid cell nuclear differentiation antigen
chr10_-_58120996 6.78 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr1_-_145826450 6.77 ENST00000462900.2
G protein-coupled receptor 89A
chr14_-_100841930 6.75 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
tryptophanyl-tRNA synthetase
chr4_-_103749313 6.68 ENST00000394803.5
ubiquitin-conjugating enzyme E2D 3
chr10_+_94451574 6.65 ENST00000492654.2
hematopoietically expressed homeobox
chr5_+_177631497 6.65 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr17_+_41150479 6.63 ENST00000589913.1
ribosomal protein L27
chr1_+_158979792 6.61 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr14_-_20801427 6.61 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr5_-_142780280 6.54 ENST00000424646.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr21_-_35284635 6.53 ENST00000429238.1
AP000304.12
chr1_-_183559693 6.52 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
neutrophil cytosolic factor 2
chr1_-_193075180 6.48 ENST00000367440.3
glutaredoxin 2
chr21_+_10862622 6.45 ENST00000302092.5
ENST00000559480.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chrX_-_16887963 6.43 ENST00000380084.4
retinoblastoma binding protein 7
chr3_+_37034823 6.39 ENST00000231790.2
ENST00000456676.2
mutL homolog 1
chr19_-_13227463 6.39 ENST00000437766.1
ENST00000221504.8
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr1_+_158979680 6.34 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr17_-_30228678 6.33 ENST00000261708.4
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr7_+_142498725 6.27 ENST00000466254.1
T cell receptor beta constant 2
chr1_+_158979686 6.26 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr6_-_31508304 6.26 ENST00000376177.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr12_-_9913489 6.25 ENST00000228434.3
ENST00000536709.1
CD69 molecule
chr2_+_102413726 6.22 ENST00000350878.4
mitogen-activated protein kinase kinase kinase kinase 4
chr11_-_14521379 6.21 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
coatomer protein complex, subunit beta 1
chr5_+_110074685 6.19 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr16_-_66864806 6.18 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NEDD8 activating enzyme E1 subunit 1
chr17_+_8191815 6.15 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr12_+_56435637 6.11 ENST00000356464.5
ENST00000552361.1
ribosomal protein S26
chr6_+_34204642 6.10 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr8_-_101719159 6.09 ENST00000520868.1
ENST00000522658.1
poly(A) binding protein, cytoplasmic 1
chr2_+_102456277 6.09 ENST00000421882.1
mitogen-activated protein kinase kinase kinase kinase 4
chr12_+_104337515 6.05 ENST00000550595.1
heat shock protein 90kDa beta (Grp94), member 1
chr2_-_158300556 6.04 ENST00000264192.3
cytohesin 1 interacting protein
chr4_-_103748880 5.97 ENST00000453744.2
ENST00000349311.8
ubiquitin-conjugating enzyme E2D 3
chr4_-_83812402 5.97 ENST00000395310.2
SEC31 homolog A (S. cerevisiae)
chr7_-_64023441 5.95 ENST00000309683.6
zinc finger protein 680
chr1_-_35450897 5.86 ENST00000373337.3
ZMYM6 neighbor
chr14_+_35761580 5.83 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr7_-_22862406 5.78 ENST00000372879.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr19_-_10491234 5.77 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
tyrosine kinase 2
chr11_-_71823715 5.76 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr5_+_96038476 5.71 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
calpastatin
chr20_+_1099233 5.67 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr9_-_128246769 5.66 ENST00000444226.1
mitogen-activated protein kinase associated protein 1
chrX_-_109590174 5.65 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr1_-_212965104 5.62 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1, MIS12 kinetochore complex component
chr9_+_108463234 5.61 ENST00000374688.1
transmembrane protein 38B
chr1_-_39339777 5.60 ENST00000397572.2
MYC binding protein
chr4_-_74853897 5.57 ENST00000296028.3
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr2_+_90259593 5.57 ENST00000471857.1
immunoglobulin kappa variable 1D-8
chr4_-_103749105 5.55 ENST00000394801.4
ENST00000394804.2
ubiquitin-conjugating enzyme E2D 3
chr19_-_10227503 5.54 ENST00000593054.1
eukaryotic translation initiation factor 3, subunit G
chr2_+_207024306 5.51 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
eukaryotic translation elongation factor 1 beta 2
chr11_+_95523621 5.47 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr5_-_149829244 5.46 ENST00000312037.5
ribosomal protein S14
chr1_+_53480598 5.41 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr2_-_89310012 5.41 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr3_-_64009658 5.39 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr8_-_90996459 5.38 ENST00000517337.1
ENST00000409330.1
nibrin
chr15_+_80351910 5.37 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX2_HOXC5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 26.9 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
8.4 42.2 GO:0002399 MHC class II protein complex assembly(GO:0002399)
6.9 27.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
5.6 39.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
3.6 7.2 GO:0002456 T cell mediated immunity(GO:0002456)
3.6 10.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
3.4 30.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
3.3 9.9 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
3.2 13.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
2.8 22.5 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.7 13.6 GO:0071918 pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
2.7 8.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
2.6 15.8 GO:0090646 mitochondrial tRNA processing(GO:0090646)
2.6 7.9 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
2.5 14.9 GO:0006741 NADP biosynthetic process(GO:0006741)
2.4 9.7 GO:0071461 cellular response to redox state(GO:0071461)
2.4 14.4 GO:1904798 positive regulation of core promoter binding(GO:1904798)
2.3 16.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
2.3 6.8 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
2.2 6.7 GO:0061010 gall bladder development(GO:0061010)
2.2 332.4 GO:0006958 complement activation, classical pathway(GO:0006958)
2.1 6.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
2.0 12.2 GO:0071233 cellular response to leucine(GO:0071233)
1.9 11.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.8 7.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
1.8 5.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
1.8 15.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.7 5.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.7 17.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.6 16.5 GO:0051096 positive regulation of helicase activity(GO:0051096)
1.6 9.6 GO:0051661 maintenance of centrosome location(GO:0051661)
1.6 4.7 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.5 4.6 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
1.5 6.2 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.5 6.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
1.4 4.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.4 7.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.4 6.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
1.3 12.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
1.3 3.9 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.3 5.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.3 5.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
1.3 5.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.3 5.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
1.3 8.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.2 5.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.2 6.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.2 3.6 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
1.2 19.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.2 18.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.2 3.5 GO:0072709 cellular response to sorbitol(GO:0072709)
1.2 4.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
1.2 5.8 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.1 3.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.1 4.4 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.1 5.4 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.1 13.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.1 3.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
1.1 10.5 GO:0042262 DNA protection(GO:0042262)
1.0 161.8 GO:0002377 immunoglobulin production(GO:0002377)
1.0 3.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.0 3.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
1.0 45.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
1.0 4.0 GO:0048539 bone marrow development(GO:0048539)
1.0 6.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.0 6.8 GO:0032594 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.9 5.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.9 5.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.9 18.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.9 30.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.9 2.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.9 2.7 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.9 5.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.9 22.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.9 4.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.9 2.6 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.9 3.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.8 4.2 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.8 7.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.8 3.3 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.8 4.1 GO:0006574 valine catabolic process(GO:0006574)
0.8 6.5 GO:0090166 Golgi disassembly(GO:0090166)
0.8 6.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.8 3.8 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.8 3.8 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.7 3.0 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.7 2.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.7 2.2 GO:0046098 guanine metabolic process(GO:0046098)
0.7 2.9 GO:0006953 acute-phase response(GO:0006953)
0.7 5.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.7 5.7 GO:0001878 response to yeast(GO:0001878)
0.7 2.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.7 9.6 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.7 0.7 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.7 3.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.6 4.5 GO:0051026 chiasma assembly(GO:0051026)
0.6 14.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 2.5 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.6 11.9 GO:0072643 interferon-gamma secretion(GO:0072643)
0.6 17.5 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.6 2.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.6 3.0 GO:0007386 compartment pattern specification(GO:0007386)
0.6 1.8 GO:0060920 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.6 2.4 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.6 7.2 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.6 3.6 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 5.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.6 1.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.6 10.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 4.6 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.6 4.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.6 4.0 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.6 7.3 GO:0008652 cellular amino acid biosynthetic process(GO:0008652)
0.6 5.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 1.6 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.5 13.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 4.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 8.0 GO:0000338 protein deneddylation(GO:0000338)
0.5 1.6 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.5 5.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.5 2.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.5 6.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.5 7.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.5 10.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.5 4.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.5 5.0 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.5 1.5 GO:0061198 fungiform papilla formation(GO:0061198)
0.5 3.9 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.5 10.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.5 6.1 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.5 4.7 GO:0006954 inflammatory response(GO:0006954)
0.5 7.0 GO:0045116 protein neddylation(GO:0045116)
0.5 6.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.5 11.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.5 2.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.5 0.9 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.5 3.7 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.5 3.7 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.5 0.9 GO:0051541 elastin metabolic process(GO:0051541)
0.5 1.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.4 11.2 GO:0030488 tRNA methylation(GO:0030488)
0.4 7.1 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.4 3.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.4 19.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.4 14.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 25.6 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.4 2.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.4 1.3 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.4 3.0 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.4 3.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 56.9 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.4 0.8 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.4 1.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.4 1.2 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.4 1.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.4 1.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.4 1.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.4 1.5 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908)
0.3 17.6 GO:0070206 protein trimerization(GO:0070206)
0.3 2.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 4.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.3 33.8 GO:0051225 spindle assembly(GO:0051225)
0.3 2.0 GO:0044351 macropinocytosis(GO:0044351)
0.3 9.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.3 27.7 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 2.3 GO:0009615 response to virus(GO:0009615)
0.3 1.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.3 10.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 2.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 1.9 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 3.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.3 3.4 GO:0051601 exocyst localization(GO:0051601)
0.3 2.4 GO:0015866 ADP transport(GO:0015866)
0.3 6.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3 2.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3 8.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 8.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3 2.7 GO:0030091 protein repair(GO:0030091)
0.3 2.4 GO:0015816 glycine transport(GO:0015816)
0.3 2.6 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.3 1.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 1.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 2.6 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.3 2.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.3 6.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 1.9 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.3 4.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 7.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 18.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.3 19.3 GO:0030574 collagen catabolic process(GO:0030574)
0.3 1.8 GO:0044092 negative regulation of molecular function(GO:0044092)
0.3 0.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 3.0 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.2 3.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 9.4 GO:1901998 toxin transport(GO:1901998)
0.2 2.2 GO:0070986 left/right axis specification(GO:0070986)
0.2 2.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.2 0.9 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 2.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 2.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 2.3 GO:0015886 heme transport(GO:0015886)
0.2 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.2 5.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.2 1.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 0.7 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 9.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 2.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.2 1.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 5.2 GO:0006825 copper ion transport(GO:0006825)
0.2 1.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.2 2.6 GO:0042832 defense response to protozoan(GO:0042832)
0.2 2.2 GO:0033197 response to vitamin E(GO:0033197)
0.2 4.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 3.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 0.6 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.2 0.6 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2 2.1 GO:0018345 protein palmitoylation(GO:0018345)
0.2 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 6.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.2 0.8 GO:0072143 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.2 1.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 4.1 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.2 5.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 0.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.2 3.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 2.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 13.6 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.2 1.4 GO:0051451 myoblast migration(GO:0051451)
0.2 2.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 5.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.2 7.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 2.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 2.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 2.8 GO:0097186 amelogenesis(GO:0097186)
0.2 1.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 4.2 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2 0.8 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 1.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 6.5 GO:0043069 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069)
0.2 3.6 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.2 2.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 23.8 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.2 0.5 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.8 GO:0030070 insulin processing(GO:0030070)
0.2 1.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 1.0 GO:0071569 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.8 GO:0001778 plasma membrane repair(GO:0001778)
0.1 2.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 3.6 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 3.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 3.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 2.2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 1.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 6.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.0 GO:0009642 response to light intensity(GO:0009642)
0.1 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 4.9 GO:0046710 GDP metabolic process(GO:0046710)
0.1 1.0 GO:0006312 mitotic recombination(GO:0006312)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 2.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.8 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.1 2.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 3.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 6.1 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.6 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 2.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 5.0 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.1 2.4 GO:0044804 nucleophagy(GO:0044804)
0.1 6.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 1.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 4.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.5 GO:0045056 transcytosis(GO:0045056)
0.1 1.1 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.0 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.1 1.7 GO:0010659 cardiac muscle cell apoptotic process(GO:0010659)
0.1 1.0 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 4.4 GO:0061053 somite development(GO:0061053)
0.1 6.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 13.6 GO:0051028 mRNA transport(GO:0051028)
0.1 2.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.3 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 1.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.1 4.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 3.2 GO:0043486 histone exchange(GO:0043486)
0.1 2.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 2.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.7 GO:0030728 ovulation(GO:0030728)
0.1 0.7 GO:0003341 cilium movement(GO:0003341)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.8 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 1.7 GO:0048240 sperm capacitation(GO:0048240)
0.1 4.3 GO:0051452 intracellular pH reduction(GO:0051452)
0.1 3.9 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 1.3 GO:0033189 response to vitamin A(GO:0033189)
0.1 4.0 GO:0035690 cellular response to drug(GO:0035690)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 6.4 GO:0006413 translational initiation(GO:0006413)
0.1 3.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 2.1 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 1.9 GO:0033198 response to ATP(GO:0033198)
0.1 0.2 GO:0061356 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) negative regulation of Wnt protein secretion(GO:0061358)
0.1 26.8 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1 8.9 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.1 2.0 GO:0010107 potassium ion import(GO:0010107)
0.1 1.7 GO:0006414 translational elongation(GO:0006414)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 4.9 GO:0006401 RNA catabolic process(GO:0006401)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0016236 macroautophagy(GO:0016236)
0.0 0.5 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 2.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.7 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 2.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.4 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.8 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.6 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.5 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.7 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0014823 response to activity(GO:0014823)
0.0 0.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.6 GO:0007498 mesoderm development(GO:0007498)
0.0 0.2 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 55.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
9.0 26.9 GO:0005715 late recombination nodule(GO:0005715)
5.6 39.1 GO:0044326 dendritic spine neck(GO:0044326)
4.2 12.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
3.5 13.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
3.2 22.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
3.0 15.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
2.6 23.1 GO:0070652 HAUS complex(GO:0070652)
2.3 7.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
2.3 9.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
2.2 8.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.1 42.6 GO:0042613 MHC class II protein complex(GO:0042613)
2.0 14.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.9 13.0 GO:0030870 Mre11 complex(GO:0030870)
1.8 1.8 GO:0005687 U4 snRNP(GO:0005687)
1.5 4.4 GO:0070557 PCNA-p21 complex(GO:0070557)
1.4 9.5 GO:0036449 microtubule minus-end(GO:0036449)
1.3 6.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.3 66.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.3 4.0 GO:0033565 ESCRT-0 complex(GO:0033565)
1.3 14.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.3 17.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.1 17.2 GO:0000346 transcription export complex(GO:0000346)
1.1 5.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.1 2.2 GO:0035061 interchromatin granule(GO:0035061)
1.1 7.6 GO:0036021 endolysosome lumen(GO:0036021)
1.0 8.3 GO:0042382 paraspeckles(GO:0042382)
1.0 4.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.0 11.1 GO:0070531 BRCA1-A complex(GO:0070531)
1.0 7.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.0 5.0 GO:0097165 nuclear stress granule(GO:0097165)
1.0 4.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
1.0 6.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.9 8.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.9 4.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.9 11.1 GO:0000243 commitment complex(GO:0000243)
0.8 15.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.8 5.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.8 9.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.8 6.5 GO:0032010 phagolysosome(GO:0032010)
0.8 4.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.7 3.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.7 16.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.7 17.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.7 6.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.7 6.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.7 3.4 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.7 7.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.7 2.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.7 7.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.7 3.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.6 1.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.6 3.1 GO:0071986 Ragulator complex(GO:0071986)
0.6 21.3 GO:0012505 endomembrane system(GO:0012505)
0.6 6.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.6 4.9 GO:0005686 U2 snRNP(GO:0005686)
0.6 1.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.6 15.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.6 10.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.6 6.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 5.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 2.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.5 3.8 GO:0071203 WASH complex(GO:0071203)
0.5 1.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.5 9.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 3.0 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.5 3.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.5 7.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.5 9.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.5 1.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.5 4.8 GO:0034709 methylosome(GO:0034709)
0.5 6.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.4 31.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 80.8 GO:0072562 blood microparticle(GO:0072562)
0.4 5.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 2.6 GO:0000813 ESCRT I complex(GO:0000813)
0.4 3.0 GO:0043203 axon hillock(GO:0043203)
0.4 5.5 GO:0042555 MCM complex(GO:0042555)
0.4 5.7 GO:0031932 TORC2 complex(GO:0031932)
0.4 12.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.4 2.4 GO:0005577 fibrinogen complex(GO:0005577)
0.4 41.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 3.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 2.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.4 1.5 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.4 1.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 1.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 1.4 GO:0000798 nuclear cohesin complex(GO:0000798)
0.3 4.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.3 4.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.3 18.6 GO:0015030 Cajal body(GO:0015030)
0.3 3.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 3.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.6 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.3 16.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 7.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 20.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 5.7 GO:0016580 Sin3 complex(GO:0016580)
0.3 2.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.3 4.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 3.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 5.7 GO:0005839 proteasome core complex(GO:0005839)
0.3 1.6 GO:0042788 polysomal ribosome(GO:0042788)
0.3 2.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 7.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 2.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 0.9 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 39.3 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 0.9 GO:0070985 TFIIK complex(GO:0070985)
0.2 2.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 5.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 1.4 GO:0061617 MICOS complex(GO:0061617)
0.2 9.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.2 2.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 3.2 GO:0000812 Swr1 complex(GO:0000812)
0.2 8.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 8.9 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.1 GO:0098574 cytoplasmic side of late endosome membrane(GO:0098560) cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 1.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 3.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 3.7 GO:0000795 synaptonemal complex(GO:0000795)
0.2 12.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 2.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.2 5.0 GO:0032420 stereocilium(GO:0032420)
0.2 3.4 GO:0000145 exocyst(GO:0000145)
0.2 10.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 0.9 GO:0042825 TAP complex(GO:0042825)
0.2 3.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 6.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 1.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.0 GO:0030061 mitochondrial crista(GO:0030061)
0.1 7.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 2.4 GO:0032433 filopodium tip(GO:0032433)
0.1 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 2.6 GO:0005814 centriole(GO:0005814)
0.1 21.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 4.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.3 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 3.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.5 GO:0036019 endolysosome(GO:0036019)
0.1 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 2.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 10.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 8.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.2 GO:0071564 npBAF complex(GO:0071564) nBAF complex(GO:0071565)
0.1 4.4 GO:0001772 immunological synapse(GO:0001772)
0.1 4.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 34.6 GO:0016607 nuclear speck(GO:0016607)
0.1 0.5 GO:0071439 clathrin complex(GO:0071439)
0.1 133.6 GO:0005615 extracellular space(GO:0005615)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 4.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.0 GO:0030056 hemidesmosome(GO:0030056)
0.1 7.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.9 GO:0031941 filamentous actin(GO:0031941)
0.1 19.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 34.2 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.1 2.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 4.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 2.5 GO:0002102 podosome(GO:0002102)
0.1 2.6 GO:0045095 keratin filament(GO:0045095)
0.1 1.7 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 5.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 4.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.6 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 9.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 8.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.1 GO:0098552 side of membrane(GO:0098552)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 58.2 GO:0050700 CARD domain binding(GO:0050700)
4.0 16.1 GO:0019770 IgG receptor activity(GO:0019770)
3.6 10.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
3.4 13.6 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
3.4 26.9 GO:0032137 guanine/thymine mispair binding(GO:0032137)
2.8 11.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
2.3 9.0 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
2.2 6.7 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
2.2 10.9 GO:0070728 leucine binding(GO:0070728)
2.2 4.4 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
2.2 503.8 GO:0003823 antigen binding(GO:0003823)
1.9 5.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
1.9 9.5 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
1.9 13.0 GO:0050733 RS domain binding(GO:0050733)
1.8 7.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
1.8 7.2 GO:0043398 HLH domain binding(GO:0043398)
1.8 5.4 GO:0070538 oleic acid binding(GO:0070538)
1.8 5.3 GO:0017130 poly(C) RNA binding(GO:0017130)
1.7 6.8 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.7 11.9 GO:0030621 U4 snRNA binding(GO:0030621)
1.7 13.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
1.6 9.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.6 4.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
1.5 12.3 GO:0004111 creatine kinase activity(GO:0004111)
1.4 4.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
1.4 7.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.4 4.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.4 21.9 GO:0004526 ribonuclease P activity(GO:0004526)
1.4 6.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
1.3 5.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.3 6.5 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
1.2 5.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.2 24.4 GO:0050786 RAGE receptor binding(GO:0050786)
1.2 9.7 GO:0046790 virion binding(GO:0046790)
1.2 4.7 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.1 6.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.1 5.6 GO:0070404 NADH binding(GO:0070404)
1.1 8.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.1 7.7 GO:0050294 steroid sulfotransferase activity(GO:0050294)
1.1 3.3 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
1.1 49.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
1.0 1.0 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
1.0 4.0 GO:0004132 dCMP deaminase activity(GO:0004132)
1.0 3.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.0 9.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.0 37.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.0 3.8 GO:0031493 nucleosomal histone binding(GO:0031493)
1.0 5.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.9 15.9 GO:0008494 translation activator activity(GO:0008494)
0.9 4.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.9 3.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.9 2.7 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.9 2.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.9 5.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.9 3.5 GO:0016936 galactoside binding(GO:0016936)
0.9 6.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8 5.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.8 9.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.8 2.5 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.8 10.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.8 7.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 2.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.7 21.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 4.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.7 2.7 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.7 6.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.7 3.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.6 5.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.6 4.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.6 2.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 10.2 GO:0070513 death domain binding(GO:0070513)
0.6 3.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 3.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.6 4.1 GO:0016289 CoA hydrolase activity(GO:0016289)
0.6 6.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.6 5.8 GO:0015266 protein channel activity(GO:0015266)
0.6 12.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.6 22.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.6 17.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6 7.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 8.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.6 13.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 4.9 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 9.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.5 2.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 1.6 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.5 2.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.5 3.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.5 1.0 GO:0017040 ceramidase activity(GO:0017040)
0.5 9.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5 5.8 GO:0005131 growth hormone receptor binding(GO:0005131)
0.5 5.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.5 0.9 GO:0046977 peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.5 2.8 GO:1990446 U1 snRNP binding(GO:1990446)
0.5 3.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.5 1.4 GO:0004802 transketolase activity(GO:0004802)
0.4 4.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 18.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 1.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.4 12.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.4 12.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.4 3.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.4 11.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.4 6.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 1.2 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.4 14.4 GO:0017091 AU-rich element binding(GO:0017091)
0.4 2.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 3.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.4 6.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.4 8.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 2.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 6.7 GO:0030515 snoRNA binding(GO:0030515)
0.4 0.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 1.4 GO:0047718 enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.3 5.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 5.7 GO:0070628 proteasome binding(GO:0070628)
0.3 1.0 GO:0015616 DNA translocase activity(GO:0015616)
0.3 9.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 3.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 69.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 1.6 GO:0008097 5S rRNA binding(GO:0008097)
0.3 3.2 GO:0001851 complement component C3b binding(GO:0001851)
0.3 5.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 2.4 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.3 19.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 1.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.3 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 3.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.3 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 2.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.3 2.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.3 2.7 GO:0035173 histone kinase activity(GO:0035173)
0.3 4.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.3 5.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 5.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 16.5 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.3 2.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.3 14.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 6.2 GO:0001968 fibronectin binding(GO:0001968)
0.3 1.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 5.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 1.0 GO:0008431 vitamin E binding(GO:0008431)
0.3 2.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.2 GO:1990254 keratin filament binding(GO:1990254)
0.2 5.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.2 3.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 2.1 GO:0089720 caspase binding(GO:0089720)
0.2 2.3 GO:0015232 heme transporter activity(GO:0015232)
0.2 5.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 5.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 6.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.9 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 5.0 GO:0004697 protein kinase C activity(GO:0004697)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 3.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 0.8 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 4.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 4.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 3.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.6 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 10.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 5.3 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.9 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.2 18.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 7.9 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2 2.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 4.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 4.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 4.7 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.2 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 5.5 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.2 2.2 GO:0030957 Tat protein binding(GO:0030957)
0.2 1.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 2.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 26.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2 8.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 0.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 1.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 4.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.6 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.1 2.0 GO:0032183 SUMO binding(GO:0032183)
0.1 21.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 4.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 6.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.5 GO:0035240 dopamine binding(GO:0035240)
0.1 1.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 8.0 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.6 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 8.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.6 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.7 GO:0005123 death receptor binding(GO:0005123)
0.1 0.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 2.9 GO:0000146 microfilament motor activity(GO:0000146)
0.1 22.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 5.2 GO:0051287 NAD binding(GO:0051287)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 5.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 6.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 3.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.8 GO:0000049 tRNA binding(GO:0000049)
0.1 5.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 20.6 GO:0045296 cadherin binding(GO:0045296)
0.1 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 16.4 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 2.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 2.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 62.9 PID BARD1 PATHWAY BARD1 signaling events
1.2 32.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.9 43.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.8 22.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6 5.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.6 8.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 2.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.5 21.4 NABA COLLAGENS Genes encoding collagen proteins
0.4 10.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 14.3 PID ATM PATHWAY ATM pathway
0.3 9.3 PID IL23 PATHWAY IL23-mediated signaling events
0.3 4.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 20.8 PID TNF PATHWAY TNF receptor signaling pathway
0.2 10.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 10.8 PID INSULIN PATHWAY Insulin Pathway
0.2 9.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 5.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 30.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 8.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 5.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 15.1 PID CDC42 PATHWAY CDC42 signaling events
0.2 5.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 6.1 PID AURORA A PATHWAY Aurora A signaling
0.2 9.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 8.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 6.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 11.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 4.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 4.4 PID ATR PATHWAY ATR signaling pathway
0.1 5.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 7.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 4.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 3.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 2.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.8 PID BMP PATHWAY BMP receptor signaling
0.1 1.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 8.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 33.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.4 67.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
1.3 47.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.2 23.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.9 12.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.8 9.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.8 7.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.8 10.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 11.7 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.7 6.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.6 11.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.6 13.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.6 61.7 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.6 6.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.6 19.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.5 10.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.5 33.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.4 2.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 41.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.4 39.8 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.4 5.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 11.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.3 2.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 2.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.3 5.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 20.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 5.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 4.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 6.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 9.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 5.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 4.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 6.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 7.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 3.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 4.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 14.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 7.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 2.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 7.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 4.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 16.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 9.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 2.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.2 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 4.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 5.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 1.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 2.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 3.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 9.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 10.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 5.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 15.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 8.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 8.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 21.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.5 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 3.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 14.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 4.5 REACTOME TRANSLATION Genes involved in Translation
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 4.1 REACTOME MEIOSIS Genes involved in Meiosis
0.1 2.7 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.4 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.1 1.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 0.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.5 REACTOME KINESINS Genes involved in Kinesins
0.1 2.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 3.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 0.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 1.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.7 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production