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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SIX5_SMARCC2_HCFC1

Z-value: 2.64

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
SIX5
ENSG00000177045.6 SIX homeobox 5
SMARCC2
ENSG00000139613.7 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
HCFC1
ENSG00000172534.9 host cell factor C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMARCC2hg19_v2_chr12_-_56583332_565833690.426.9e-11Click!
HCFC1hg19_v2_chrX_-_153236819_153236978,
hg19_v2_chrX_-_153236620_153236684,
hg19_v2_chrX_-_153237258_153237295		0.421.6e-10Click!
SIX5hg19_v2_chr19_-_46272106_46272115-0.407.4e-10Click!

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_150754935 48.26 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr3_+_183892635 46.64 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_-_47354023 44.51 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr11_-_82997371 42.20 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr15_+_40453204 41.25 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chrX_-_107334750 40.79 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr17_-_47492164 40.13 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
PHB
prohibitin
chr2_+_172544294 39.84 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr19_-_47354082 39.36 ENST00000593442.1
ENST00000263270.6
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr11_-_82997013 39.04 ENST00000529073.1
ENST00000529611.1
CCDC90B
coiled-coil domain containing 90B
chr14_+_77924204 35.80 ENST00000555133.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr11_-_82997420 35.61 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chrX_-_107334790 34.65 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr2_+_63816295 33.84 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr22_+_30163340 31.78 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr7_-_132766818 30.63 ENST00000262570.5
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_172544182 30.59 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr14_+_77924373 30.51 ENST00000216479.3
ENST00000535854.2
ENST00000555517.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr8_+_110346546 28.84 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
ENY2
enhancer of yellow 2 homolog (Drosophila)
chr19_-_47551836 28.82 ENST00000253047.6
TMEM160
transmembrane protein 160
chr1_+_156024525 28.10 ENST00000368305.4
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr7_-_132766800 28.09 ENST00000542753.1
ENST00000448878.1
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_172543919 28.01 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr2_+_172544011 27.93 ENST00000508530.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr2_+_172543967 27.63 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr14_+_97263641 27.14 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr11_+_16760161 26.92 ENST00000524439.1
ENST00000422258.2
ENST00000528634.1
ENST00000525684.1
C11orf58
chromosome 11 open reading frame 58
chr6_+_31633902 25.70 ENST00000375865.2
ENST00000375866.2
CSNK2B
casein kinase 2, beta polypeptide
chr2_+_63816087 25.61 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr1_+_155278539 25.48 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr10_-_104262426 25.42 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr11_-_134123142 25.13 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr1_+_224544572 24.79 ENST00000366857.5
ENST00000366856.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr6_-_5004241 24.59 ENST00000319533.5
ENST00000380051.2
RPP40
ribonuclease P/MRP 40kDa subunit
chr19_-_54618650 24.48 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr22_-_41682172 24.47 ENST00000356244.3
RANGAP1
Ran GTPase activating protein 1
chr1_+_156737292 24.01 ENST00000271526.4
ENST00000353233.3
PRCC
papillary renal cell carcinoma (translocation-associated)
chr1_-_26233423 23.88 ENST00000357865.2
STMN1
stathmin 1
chr10_-_104262460 23.72 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr1_+_156024552 23.59 ENST00000368304.5
ENST00000368302.3
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr19_-_54619006 23.59 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr1_+_155278625 23.36 ENST00000368356.4
ENST00000356657.6
FDPS
farnesyl diphosphate synthase
chr1_+_224544552 23.27 ENST00000465271.1
ENST00000366858.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr20_-_62587735 23.15 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
UCKL1
uridine-cytidine kinase 1-like 1
chr19_-_42463418 22.91 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1
Rab acceptor 1 (prenylated)
chr4_+_1723197 22.90 ENST00000485989.2
ENST00000313288.4
TACC3
transforming, acidic coiled-coil containing protein 3
chr10_+_124913930 22.75 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr3_-_98241358 22.50 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr12_-_56709786 21.69 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
RP11-977G19.10
CNPY2
Uncharacterized protein
canopy FGF signaling regulator 2
chr11_+_114310102 21.68 ENST00000265881.5
REXO2
RNA exonuclease 2
chr20_+_62694461 21.20 ENST00000343484.5
ENST00000395053.3
TCEA2
transcription elongation factor A (SII), 2
chr6_+_31633833 21.12 ENST00000375882.2
ENST00000375880.2
CSNK2B
CSNK2B-LY6G5B-1181
casein kinase 2, beta polypeptide
Uncharacterized protein
chr3_-_98241760 21.01 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr19_-_1095330 20.37 ENST00000586746.1
POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr17_-_21117902 20.33 ENST00000317635.5
TMEM11
transmembrane protein 11
chr13_-_31736027 20.30 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr11_+_114310164 20.15 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2
RNA exonuclease 2
chr20_-_48732472 20.15 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr12_-_56709674 19.60 ENST00000551286.1
ENST00000549318.1
CNPY2
RP11-977G19.10
canopy FGF signaling regulator 2
Uncharacterized protein
chr1_+_44440575 19.58 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr5_-_175815565 19.51 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16
NOP16 nucleolar protein
chr17_-_46178741 19.27 ENST00000581003.1
ENST00000225603.4
CBX1
chromobox homolog 1
chr11_-_65626753 19.24 ENST00000526975.1
ENST00000531413.1
CFL1
cofilin 1 (non-muscle)
chr12_-_56710118 18.77 ENST00000273308.4
CNPY2
canopy FGF signaling regulator 2
chr17_-_46178527 18.74 ENST00000393408.3
CBX1
chromobox homolog 1
chrX_-_48980098 18.66 ENST00000156109.5
GPKOW
G patch domain and KOW motifs
chr16_+_4674814 18.49 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr20_-_32891151 18.39 ENST00000217426.2
AHCY
adenosylhomocysteinase
chr1_-_26232951 18.37 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr17_-_47492236 18.00 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr1_+_47799446 17.93 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr14_+_24702099 17.76 ENST00000420554.2
GMPR2
guanosine monophosphate reductase 2
chr11_+_114310237 17.61 ENST00000539119.1
REXO2
RNA exonuclease 2
chr6_+_42981922 17.44 ENST00000326974.4
ENST00000244670.8
KLHDC3
kelch domain containing 3
chr12_+_56546363 17.40 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr16_+_4674787 17.09 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr6_-_38670897 17.02 ENST00000373365.4
GLO1
glyoxalase I
chr19_+_17416609 16.90 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr2_-_232646015 16.87 ENST00000287600.4
PDE6D
phosphodiesterase 6D, cGMP-specific, rod, delta
chrX_+_155110956 16.81 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
VAMP7
vesicle-associated membrane protein 7
chr19_+_6361754 16.75 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr7_-_100888337 16.74 ENST00000223136.4
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr10_+_124913793 16.70 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr19_+_17416457 16.66 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr16_-_15149828 16.63 ENST00000566419.1
ENST00000568320.1
NTAN1
N-terminal asparagine amidase
chr19_-_2456922 16.57 ENST00000582871.1
ENST00000325327.3
LMNB2
lamin B2
chr20_+_30327063 16.47 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr3_+_169940153 16.37 ENST00000295797.4
PRKCI
protein kinase C, iota
chr6_-_110500905 16.31 ENST00000392587.2
WASF1
WAS protein family, member 1
chr8_-_74884459 16.14 ENST00000522337.1
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr17_-_40950698 16.07 ENST00000328434.7
COA3
cytochrome c oxidase assembly factor 3
chr2_-_219134822 15.90 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr15_-_52861029 15.87 ENST00000561650.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr14_-_24701539 15.85 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1
NEDD8
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr1_+_45205478 15.85 ENST00000452259.1
ENST00000372224.4
KIF2C
kinesin family member 2C
chr11_+_74660278 15.73 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_+_45205498 15.72 ENST00000372218.4
KIF2C
kinesin family member 2C
chr12_+_32832134 15.71 ENST00000452533.2
DNM1L
dynamin 1-like
chr11_-_47447767 15.71 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr14_+_24702127 15.57 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
GMPR2
guanosine monophosphate reductase 2
chr6_+_30875955 15.56 ENST00000259895.4
ENST00000539324.1
ENST00000376316.2
ENST00000453897.2
GTF2H4
general transcription factor IIH, polypeptide 4, 52kDa
chr1_-_156710859 15.47 ENST00000361531.2
ENST00000412846.1
MRPL24
mitochondrial ribosomal protein L24
chr9_+_116037922 15.27 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr15_-_52861394 15.23 ENST00000563277.1
ENST00000566423.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr19_+_12917364 15.21 ENST00000221486.4
RNASEH2A
ribonuclease H2, subunit A
chr1_-_156710916 15.18 ENST00000368211.4
MRPL24
mitochondrial ribosomal protein L24
chr11_+_82783097 15.17 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr14_-_23398565 15.15 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
PRMT5
protein arginine methyltransferase 5
chr19_+_35225060 15.06 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chr7_-_100888313 14.98 ENST00000442303.1
FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr3_+_158991025 14.94 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_-_36615051 14.81 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr12_+_56546223 14.74 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr14_+_24702073 14.64 ENST00000399440.2
GMPR2
guanosine monophosphate reductase 2
chr19_+_1241732 14.34 ENST00000215375.2
ENST00000395633.1
ENST00000591660.1
ATP5D
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr1_-_36615065 14.33 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr14_-_68141535 14.16 ENST00000554659.1
VTI1B
vesicle transport through interaction with t-SNAREs 1B
chr6_-_110501200 14.12 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1
WAS protein family, member 1
chr12_+_32832203 14.11 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L
dynamin 1-like
chr12_+_93861282 14.10 ENST00000552217.1
ENST00000393128.4
ENST00000547098.1
MRPL42
mitochondrial ribosomal protein L42
chr12_+_93861264 14.08 ENST00000549982.1
ENST00000361630.2
MRPL42
mitochondrial ribosomal protein L42
chr6_+_88182643 14.04 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr10_+_111985713 14.03 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr15_-_52861323 14.01 ENST00000569723.1
ENST00000249822.4
ENST00000567669.1
ENST00000569281.2
ENST00000563566.1
ENST00000567830.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr1_-_10532531 13.96 ENST00000377036.2
ENST00000377038.3
DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
chr8_-_63951730 13.84 ENST00000260118.6
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr21_-_15755446 13.77 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr19_+_7600584 13.74 ENST00000600737.1
PNPLA6
patatin-like phospholipase domain containing 6
chr14_+_24701819 13.73 ENST00000560139.1
ENST00000559910.1
GMPR2
guanosine monophosphate reductase 2
chrX_-_118986911 13.66 ENST00000276201.2
ENST00000345865.2
UPF3B
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr11_+_67374323 13.60 ENST00000322776.6
ENST00000532303.1
ENST00000532244.1
ENST00000528328.1
ENST00000529927.1
ENST00000532343.1
ENST00000415352.2
ENST00000533075.1
ENST00000529867.1
ENST00000530638.1
NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr20_+_62694590 13.59 ENST00000339217.4
TCEA2
transcription elongation factor A (SII), 2
chr3_-_167452298 13.54 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr19_+_50354393 13.52 ENST00000391842.1
PTOV1
prostate tumor overexpressed 1
chr11_+_60681346 13.51 ENST00000227525.3
TMEM109
transmembrane protein 109
chr11_-_47447970 13.49 ENST00000298852.3
ENST00000530912.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr5_-_132112921 13.48 ENST00000378721.4
ENST00000378701.1
SEPT8
septin 8
chrX_+_77154935 13.44 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr14_+_24701628 13.42 ENST00000355299.4
ENST00000559836.1
GMPR2
guanosine monophosphate reductase 2
chr19_+_36705504 13.36 ENST00000456324.1
ZNF146
zinc finger protein 146
chr1_-_54304212 13.29 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr2_-_99952769 13.26 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
TXNDC9
thioredoxin domain containing 9
chr19_-_19030157 13.23 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
COPE
coatomer protein complex, subunit epsilon
chr18_-_43684186 13.22 ENST00000590406.1
ENST00000282050.2
ENST00000590324.1
ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr6_-_42981651 13.20 ENST00000244711.3
MEA1
male-enhanced antigen 1
chr14_+_102430855 13.17 ENST00000360184.4
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr10_+_103892787 13.13 ENST00000278070.2
ENST00000413464.2
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr5_-_132112907 13.11 ENST00000458488.2
SEPT8
septin 8
chr14_-_68162464 13.01 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr5_+_85913721 12.99 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
COX7C
cytochrome c oxidase subunit VIIc
chr1_-_54303934 12.94 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr16_+_67881029 12.80 ENST00000569436.2
ENST00000568396.2
NUTF2
nuclear transport factor 2
chr20_-_47804894 12.69 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chrX_+_47050236 12.53 ENST00000377351.4
UBA1
ubiquitin-like modifier activating enzyme 1
chr3_-_167452703 12.52 ENST00000497056.2
ENST00000473645.2
PDCD10
programmed cell death 10
chr12_+_861717 12.44 ENST00000535572.1
WNK1
WNK lysine deficient protein kinase 1
chr13_-_31736478 12.39 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr4_+_174292058 12.32 ENST00000296504.3
SAP30
Sin3A-associated protein, 30kDa
chr3_-_167452614 12.28 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10
programmed cell death 10
chr2_-_170430277 12.27 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr1_-_26232522 12.20 ENST00000399728.1
STMN1
stathmin 1
chr12_+_12966250 12.16 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr5_-_132113559 12.15 ENST00000448933.1
SEPT8
septin 8
chr16_+_67880574 12.09 ENST00000219169.4
NUTF2
nuclear transport factor 2
chr19_+_50354430 12.03 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr12_-_57146095 11.96 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr8_-_99129338 11.86 ENST00000520507.1
HRSP12
heat-responsive protein 12
chr17_-_40075197 11.86 ENST00000590770.1
ENST00000590151.1
ACLY
ATP citrate lyase
chrX_+_48334549 11.79 ENST00000019019.2
ENST00000348411.2
ENST00000396894.4
FTSJ1
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr21_-_35288284 11.77 ENST00000290299.2
ATP5O
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr11_-_60674037 11.76 ENST00000541371.1
ENST00000227524.4
PRPF19
pre-mRNA processing factor 19
chr1_-_44820880 11.72 ENST00000372257.2
ENST00000457571.1
ENST00000452396.1
ERI3
ERI1 exoribonuclease family member 3
chr5_+_5422778 11.71 ENST00000296564.7
KIAA0947
KIAA0947
chr5_+_178286925 11.68 ENST00000322434.3
ZNF354B
zinc finger protein 354B
chr7_+_135242652 11.60 ENST00000285968.6
ENST00000440390.2
NUP205
nucleoporin 205kDa
chr17_-_26662440 11.55 ENST00000578122.1
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr19_+_36236491 11.53 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr8_-_74884341 11.53 ENST00000284811.8
TCEB1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr16_+_3074002 11.50 ENST00000326266.8
ENST00000574549.1
ENST00000575576.1
ENST00000253952.9
THOC6
THO complex 6 homolog (Drosophila)
chr1_-_244615425 11.47 ENST00000366535.3
ADSS
adenylosuccinate synthase
chr19_+_54619125 11.44 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr1_+_38158090 11.43 ENST00000373055.1
ENST00000327331.2
CDCA8
cell division cycle associated 8
chr18_+_60382672 11.39 ENST00000400316.4
ENST00000262719.5
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr16_+_2097403 11.28 ENST00000219476.3
TSC2
tuberous sclerosis 2
chr8_-_144699628 11.27 ENST00000529048.1
ENST00000529064.1
TSTA3
tissue specific transplantation antigen P35B
chr17_+_66243715 11.12 ENST00000359904.3
AMZ2
archaelysin family metallopeptidase 2
chr12_-_102455846 11.10 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr7_+_140396946 11.09 ENST00000476470.1
ENST00000471136.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr7_+_128502871 10.99 ENST00000249289.4
ATP6V1F
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr5_+_118788138 10.95 ENST00000256216.6
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr1_+_151227179 10.94 ENST00000368884.3
ENST00000368881.4
PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr2_-_203776864 10.93 ENST00000261015.4
WDR12
WD repeat domain 12
chr1_+_38478378 10.90 ENST00000373014.4
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr19_-_50168962 10.74 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3
interferon regulatory factor 3
chr2_+_242089833 10.72 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr1_-_155232221 10.68 ENST00000355379.3
SCAMP3
secretory carrier membrane protein 3
chr6_-_52149475 10.62 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
MCM3
minichromosome maintenance complex component 3
chr5_+_118788433 10.60 ENST00000414835.2
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr5_+_118788261 10.60 ENST00000504811.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr19_-_50169064 10.60 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3
interferon regulatory factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 75.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
14.0 154.0 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
12.3 61.5 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
10.9 54.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
10.5 31.6 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
10.3 41.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
9.7 58.1 GO:2000323 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
8.7 43.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.3 41.4 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
8.0 48.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
7.1 35.6 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
7.1 56.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
7.1 21.3 GO:0042351 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
7.0 42.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
6.9 130.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
6.7 60.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
6.6 19.7 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
6.5 6.5 GO:0051781 positive regulation of cell division(GO:0051781)
6.4 6.4 GO:0006624 vacuolar protein processing(GO:0006624)
6.1 42.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
6.0 17.9 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
5.9 23.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
5.4 86.9 GO:0006107 oxaloacetate metabolic process(GO:0006107)
5.1 15.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
4.9 14.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
4.9 58.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
4.8 52.7 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
4.7 14.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
4.6 18.5 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
4.6 13.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
4.3 34.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
4.2 12.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
4.0 16.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
4.0 12.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
4.0 158.3 GO:0042407 cristae formation(GO:0042407)
3.9 27.1 GO:0090166 histone H3-S10 phosphorylation(GO:0043987) Golgi disassembly(GO:0090166)
3.9 23.1 GO:0044211 CTP salvage(GO:0044211)
3.8 11.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
3.8 15.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
3.8 30.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
3.7 25.7 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
3.6 43.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
3.5 35.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
3.5 10.4 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
3.4 17.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
3.4 20.5 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
3.4 17.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
3.3 13.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
3.2 22.6 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
3.0 17.9 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
3.0 17.8 GO:0048254 snoRNA localization(GO:0048254)
2.9 28.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
2.8 8.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
2.8 75.1 GO:0043101 purine-containing compound salvage(GO:0043101)
2.8 16.6 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
2.7 5.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.6 13.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.5 45.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
2.4 14.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
2.4 14.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
2.3 6.8 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
2.3 6.8 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
2.3 11.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
2.2 6.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
2.2 161.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
2.1 8.5 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
2.1 4.2 GO:0060348 bone development(GO:0060348)
2.1 6.3 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
2.1 8.4 GO:0031648 protein destabilization(GO:0031648)
2.1 14.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
2.0 24.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
2.0 4.0 GO:0031627 telomeric loop formation(GO:0031627)
1.9 18.6 GO:0042373 vitamin K metabolic process(GO:0042373)
1.8 16.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
1.8 5.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.8 21.3 GO:0039530 MDA-5 signaling pathway(GO:0039530)
1.8 12.4 GO:0016074 snoRNA metabolic process(GO:0016074)
1.8 8.8 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
1.7 5.0 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
1.6 8.0 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.6 30.5 GO:0031293 Notch receptor processing(GO:0007220) membrane protein intracellular domain proteolysis(GO:0031293)
1.6 39.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
1.6 4.7 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
1.5 1.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
1.5 49.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.4 44.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.4 14.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
1.4 18.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
1.4 4.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
1.4 4.2 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
1.4 19.3 GO:0051974 negative regulation of telomerase activity(GO:0051974)
1.3 46.7 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
1.3 4.0 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.3 5.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
1.3 48.0 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.3 27.2 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
1.3 3.8 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
1.3 12.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.3 3.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.3 26.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 12.6 GO:0043248 proteasome assembly(GO:0043248)
1.3 16.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
1.2 3.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
1.2 8.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.2 3.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
1.1 11.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.1 3.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.1 10.0 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.1 3.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
1.1 2.2 GO:0018126 protein hydroxylation(GO:0018126)
1.0 6.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.0 10.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.0 2.9 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.9 18.6 GO:0007005 mitochondrion organization(GO:0007005)
0.9 8.3 GO:0072718 response to cisplatin(GO:0072718)
0.9 9.1 GO:0051597 response to methylmercury(GO:0051597)
0.9 2.7 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.9 10.8 GO:0009642 response to light intensity(GO:0009642)
0.9 19.6 GO:0035855 megakaryocyte development(GO:0035855)
0.9 3.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.9 15.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.8 3.4 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.8 3.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072) negative regulation of protein kinase C signaling(GO:0090038)
0.8 3.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.8 2.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.8 2.5 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.8 5.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.8 2.4 GO:0009153 ADP biosynthetic process(GO:0006172) purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.8 2.4 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.8 4.0 GO:0006574 valine catabolic process(GO:0006574)
0.8 15.7 GO:0006465 signal peptide processing(GO:0006465)
0.8 3.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.8 1.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.8 11.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.8 7.6 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.8 3.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.8 162.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.7 3.0 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.7 47.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.7 33.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.7 3.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.7 2.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.7 7.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.7 2.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.7 15.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.7 0.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.7 9.0 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.7 6.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.7 3.3 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) dTTP metabolic process(GO:0046075)
0.6 1.9 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 7.6 GO:0006527 arginine catabolic process(GO:0006527)
0.6 4.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.6 8.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.6 0.6 GO:0040031 snRNA modification(GO:0040031)
0.6 9.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.6 9.3 GO:0045116 protein neddylation(GO:0045116)
0.6 7.4 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.6 33.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.6 40.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.6 18.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.6 4.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.6 3.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.6 8.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5 11.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.5 13.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.5 15.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 4.2 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.5 1.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.5 7.8 GO:0090344 negative regulation of cell aging(GO:0090344)
0.5 3.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.5 9.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.5 2.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 3.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.5 1.5 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.5 2.0 GO:1904753 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.5 4.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.5 32.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.5 7.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.5 1.4 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.5 4.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.4 0.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 5.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.4 21.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.4 5.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.4 6.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 8.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.4 9.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.4 4.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 3.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 9.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 4.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.4 11.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 2.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 2.9 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.4 1.4 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.3 12.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.3 4.8 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.3 10.3 GO:0006101 citrate metabolic process(GO:0006101)
0.3 14.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.3 7.7 GO:0001825 blastocyst formation(GO:0001825)
0.3 2.3 GO:0071554 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.3 5.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 2.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.3 13.5 GO:0006270 DNA replication initiation(GO:0006270)
0.3 10.1 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.3 2.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 5.0 GO:0031167 rRNA methylation(GO:0031167)
0.3 5.0 GO:0098792 xenophagy(GO:0098792)
0.3 1.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.3 4.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 1.2 GO:0019081 viral translation(GO:0019081) viral translational termination-reinitiation(GO:0075525)
0.3 5.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.3 1.7 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.3 0.9 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.3 15.6 GO:0006301 postreplication repair(GO:0006301)
0.3 4.8 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.3 7.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 8.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.3 7.5 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.3 7.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 1.5 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.2 1.5 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.2 2.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 17.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 1.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 1.2 GO:1903286 regulation of potassium ion import(GO:1903286)
0.2 0.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 12.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 15.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 4.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 2.9 GO:0016236 macroautophagy(GO:0016236)
0.2 0.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 10.6 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.2 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.4 GO:0050747 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 5.7 GO:0001504 neurotransmitter uptake(GO:0001504)
0.2 2.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 0.2 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527) endoplasmic reticulum to cytosol transport(GO:1903513)
0.2 1.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.3 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.2 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 3.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 5.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 0.5 GO:0043307 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.2 2.8 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344)
0.2 0.6 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 1.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 1.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 0.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 2.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 3.6 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 3.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 13.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 4.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 5.7 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 16.7 GO:0000910 cytokinesis(GO:0000910)
0.1 0.7 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 4.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 4.1 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 3.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 0.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 3.5 GO:1901661 quinone metabolic process(GO:1901661)
0.1 12.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 2.6 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 0.4 GO:2001140 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.1 4.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 3.2 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1 1.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 38.5 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 1.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 4.0 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 2.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 1.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 6.0 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 2.4 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 3.7 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 0.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 1.6 GO:0048821 erythrocyte development(GO:0048821)
0.1 5.1 GO:0048678 response to axon injury(GO:0048678)
0.1 5.5 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 6.2 GO:0006310 DNA recombination(GO:0006310)
0.1 2.1 GO:0009409 response to cold(GO:0009409)
0.1 21.1 GO:0051260 protein homooligomerization(GO:0051260)
0.1 0.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.9 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.7 GO:0016180 snRNA processing(GO:0016180)
0.1 6.3 GO:0045471 response to ethanol(GO:0045471)
0.1 0.4 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.1 0.9 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.1 1.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 2.0 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.1 6.4 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.1 8.2 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 1.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 0.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 6.5 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 3.9 GO:0008380 RNA splicing(GO:0008380)
0.0 4.3 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 0.2 GO:0002887 negative regulation of immunoglobulin production(GO:0002638) negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) negative regulation of mast cell degranulation(GO:0043305)
0.0 4.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 5.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 2.5 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.6 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 2.2 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0 0.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.5 GO:0050770 regulation of axonogenesis(GO:0050770)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
13.1 39.4 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
12.5 75.1 GO:1902560 GMP reductase complex(GO:1902560)
12.1 48.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
11.2 78.5 GO:0061617 MICOS complex(GO:0061617)
10.5 31.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
10.3 51.7 GO:0071986 Ragulator complex(GO:0071986)
8.2 49.1 GO:0002177 manchette(GO:0002177)
7.6 38.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
7.6 38.0 GO:0001940 male pronucleus(GO:0001940)
7.6 37.8 GO:0035370 UBC13-UEV1A complex(GO:0035370)
7.3 51.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
6.8 129.1 GO:0036020 endolysosome membrane(GO:0036020)
6.4 121.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
5.5 166.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
5.2 15.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
5.1 20.5 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
4.9 19.7 GO:0031166 integral component of vacuolar membrane(GO:0031166)
4.8 14.5 GO:1902636 kinociliary basal body(GO:1902636)
4.6 13.7 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
4.1 24.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
4.0 39.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
3.8 15.3 GO:0071001 U4/U6 snRNP(GO:0071001)
3.8 22.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
3.8 41.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
3.6 50.0 GO:0031209 SCAR complex(GO:0031209)
3.5 10.6 GO:0031262 Ndc80 complex(GO:0031262)
3.3 36.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
3.1 36.8 GO:0030008 TRAPP complex(GO:0030008)
3.1 27.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
3.0 24.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
3.0 24.1 GO:0070552 BRISC complex(GO:0070552)
2.9 11.6 GO:0044611 nuclear pore inner ring(GO:0044611)
2.8 14.0 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
2.8 30.5 GO:0070765 gamma-secretase complex(GO:0070765)
2.6 105.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.6 20.7 GO:0032133 chromosome passenger complex(GO:0032133)
2.5 44.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
2.4 11.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
2.3 48.1 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
2.3 6.8 GO:0030689 Noc complex(GO:0030689)
2.3 6.8 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.2 15.7 GO:0005787 signal peptidase complex(GO:0005787)
2.2 9.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.2 20.0 GO:0005638 lamin filament(GO:0005638)
2.2 6.6 GO:0018444 translation release factor complex(GO:0018444)
2.2 19.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.1 4.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
2.0 32.1 GO:0016461 unconventional myosin complex(GO:0016461)
2.0 15.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.9 28.8 GO:0000124 SAGA complex(GO:0000124)
1.9 7.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.9 24.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.8 10.9 GO:0070545 PeBoW complex(GO:0070545)
1.8 26.4 GO:0045277 respiratory chain complex IV(GO:0045277)
1.6 11.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.6 6.4 GO:0070761 pre-snoRNP complex(GO:0070761)
1.6 9.5 GO:1990130 Iml1 complex(GO:1990130)
1.6 17.3 GO:0005686 U2 snRNP(GO:0005686)
1.5 16.5 GO:0043203 axon hillock(GO:0043203)
1.5 8.8 GO:0071817 MMXD complex(GO:0071817)
1.5 14.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.4 11.4 GO:0005687 U4 snRNP(GO:0005687)
1.3 43.1 GO:0005640 nuclear outer membrane(GO:0005640)
1.3 9.3 GO:0016272 prefoldin complex(GO:0016272)
1.3 13.2 GO:0030126 COPI vesicle coat(GO:0030126)
1.3 7.9 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.3 10.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.3 31.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.3 15.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.3 16.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.2 33.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
1.2 6.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
1.2 34.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.1 12.3 GO:0005869 dynactin complex(GO:0005869)
1.1 7.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.1 4.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.1 6.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.0 3.1 GO:0071159 NF-kappaB complex(GO:0071159)
1.0 5.2 GO:0033263 CORVET complex(GO:0033263)
1.0 18.4 GO:0034709 methylosome(GO:0034709)
1.0 7.1 GO:0030870 Mre11 complex(GO:0030870)
1.0 5.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
1.0 7.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.0 4.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.0 16.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.0 34.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.9 23.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.9 63.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.8 20.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.8 45.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.8 47.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.8 5.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 5.5 GO:0032009 early phagosome(GO:0032009)
0.7 41.5 GO:0005871 kinesin complex(GO:0005871)
0.7 5.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.7 2.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.7 16.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.7 2.7 GO:0055087 Ski complex(GO:0055087)
0.7 3.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.7 2.6 GO:0070876 SOSS complex(GO:0070876)
0.6 1.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 1.9 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.6 15.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.6 2.5 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.6 4.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.6 7.6 GO:0090543 Flemming body(GO:0090543)
0.6 6.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.6 133.8 GO:0043209 myelin sheath(GO:0043209)
0.6 7.4 GO:0070469 respiratory chain(GO:0070469)
0.6 4.0 GO:0072487 MSL complex(GO:0072487)
0.6 3.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 2.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.5 12.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.5 4.1 GO:0005642 annulate lamellae(GO:0005642)
0.5 1.5 GO:0097513 myosin II filament(GO:0097513)
0.5 3.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 7.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 21.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.5 25.6 GO:0031201 SNARE complex(GO:0031201)
0.5 1.4 GO:0070939 Dsl1p complex(GO:0070939)
0.4 4.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 38.6 GO:0005643 nuclear pore(GO:0005643)
0.4 9.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 4.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.4 26.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.4 9.0 GO:0070822 Sin3-type complex(GO:0070822)
0.4 6.9 GO:0005685 U1 snRNP(GO:0005685)
0.3 16.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 32.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.3 1.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.3 32.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 11.4 GO:0016592 mediator complex(GO:0016592)
0.3 4.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 21.2 GO:0005811 lipid particle(GO:0005811)
0.3 1.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 13.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 4.7 GO:0005682 U5 snRNP(GO:0005682)
0.3 3.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 5.0 GO:0000421 autophagosome membrane(GO:0000421)
0.3 32.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.3 0.8 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 102.5 GO:0005740 mitochondrial envelope(GO:0005740)
0.2 2.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 6.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 1.4 GO:0005675 core TFIIH complex(GO:0000439) holo TFIIH complex(GO:0005675)
0.2 3.4 GO:0032420 stereocilium(GO:0032420)
0.2 2.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 8.9 GO:0030684 preribosome(GO:0030684)
0.2 8.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.2 4.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 1.7 GO:0042382 paraspeckles(GO:0042382)
0.2 8.5 GO:0072686 mitotic spindle(GO:0072686)
0.2 6.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 4.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 23.4 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 8.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 3.6 GO:0031143 pseudopodium(GO:0031143)
0.2 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1 4.8 GO:0005771 multivesicular body(GO:0005771)
0.1 2.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.4 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 8.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 23.0 GO:0005819 spindle(GO:0005819)
0.1 2.1 GO:0002102 podosome(GO:0002102)
0.1 1.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 12.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 10.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.5 GO:0005856 cytoskeleton(GO:0005856)
0.1 0.7 GO:0032039 integrator complex(GO:0032039)
0.1 2.2 GO:0015935 small ribosomal subunit(GO:0015935)
0.1 3.7 GO:0030496 midbody(GO:0030496)
0.1 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.7 GO:0031105 septin complex(GO:0031105)
0.1 0.2 GO:0016589 NURF complex(GO:0016589)
0.1 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 8.6 GO:0070382 exocytic vesicle(GO:0070382)
0.1 180.5 GO:0070062 extracellular exosome(GO:0070062)
0.1 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 20.0 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.1 11.2 GO:0009986 cell surface(GO:0009986)
0.0 2.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 38.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.7 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.5 58.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
12.5 75.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
11.9 59.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
8.3 41.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
8.1 48.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
7.7 154.8 GO:0045504 dynein heavy chain binding(GO:0045504)
7.0 42.1 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
6.8 27.1 GO:0031493 nucleosomal histone binding(GO:0031493)
5.9 130.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
5.9 41.1 GO:0004849 uridine kinase activity(GO:0004849)
4.9 34.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
4.9 48.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
4.6 18.6 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
4.4 21.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
4.2 38.0 GO:1990226 histone methyltransferase binding(GO:1990226)
3.9 19.5 GO:0000403 Y-form DNA binding(GO:0000403)
3.8 26.7 GO:0030621 U4 snRNA binding(GO:0030621)
3.8 15.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
3.5 10.4 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
3.4 10.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
3.4 10.1 GO:0033149 FFAT motif binding(GO:0033149)
3.3 32.9 GO:0019237 centromeric DNA binding(GO:0019237)
3.3 16.5 GO:0061676 importin-alpha family protein binding(GO:0061676)
3.3 19.7 GO:1903135 cupric ion binding(GO:1903135)
3.2 35.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
3.2 15.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
3.0 12.0 GO:0003697 single-stranded DNA binding(GO:0003697)
2.9 35.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
2.9 32.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
2.9 14.5 GO:0002046 opsin binding(GO:0002046)
2.9 45.8 GO:0004526 ribonuclease P activity(GO:0004526)
2.8 14.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
2.6 10.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
2.6 15.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.5 7.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.5 7.4 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
2.4 11.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
2.2 13.2 GO:0043532 angiostatin binding(GO:0043532)
2.1 17.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
2.1 12.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
2.1 8.3 GO:0004594 pantothenate kinase activity(GO:0004594)
2.1 14.5 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.9 5.7 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.9 84.8 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
1.9 30.1 GO:0051400 BH domain binding(GO:0051400)
1.8 37.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.8 14.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.8 12.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.7 5.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.6 47.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.6 4.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.6 63.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
1.5 7.6 GO:0016403 dimethylargininase activity(GO:0016403)
1.5 4.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.5 20.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.5 51.1 GO:0001671 ATPase activator activity(GO:0001671)
1.4 52.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
1.4 54.0 GO:0008536 Ran GTPase binding(GO:0008536)
1.3 7.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.3 10.4 GO:0070883 pre-miRNA binding(GO:0070883)
1.3 9.0 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.2 112.2 GO:0032947 protein complex scaffold(GO:0032947)
1.2 4.8 GO:0042809 vitamin D receptor binding(GO:0042809)
1.2 5.8 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
1.1 50.2 GO:0031369 translation initiation factor binding(GO:0031369)
1.1 21.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.1 6.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.0 24.9 GO:0070064 proline-rich region binding(GO:0070064)
1.0 13.2 GO:0045503 dynein light chain binding(GO:0045503)
1.0 5.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.0 4.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.0 20.4 GO:0001055 RNA polymerase II activity(GO:0001055)
1.0 17.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.0 11.5 GO:0042301 phosphate ion binding(GO:0042301)
0.9 47.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.9 26.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.9 6.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.9 25.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.9 9.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.9 3.5 GO:0097001 ceramide binding(GO:0097001)
0.8 2.5 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.8 5.8 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.8 11.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.8 7.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.8 11.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.8 3.1 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.8 7.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.8 9.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.7 17.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.7 14.9 GO:0005537 mannose binding(GO:0005537)
0.7 4.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.7 13.8 GO:0008242 omega peptidase activity(GO:0008242)
0.7 12.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.7 2.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.7 2.8 GO:0005046 KDEL sequence binding(GO:0005046)
0.7 15.4 GO:0004697 protein kinase C activity(GO:0004697)
0.7 6.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.7 3.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.7 3.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.6 1.9 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.6 7.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.6 5.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.6 31.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 20.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.6 33.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.6 122.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 3.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.6 21.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.5 4.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.5 10.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.5 7.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.5 4.1 GO:0034452 dynactin binding(GO:0034452)
0.5 55.9 GO:0003774 motor activity(GO:0003774)
0.5 13.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.5 1.4 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.4 5.8 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.4 1.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.4 1.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.4 12.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.4 2.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 4.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 16.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 11.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 6.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 18.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 1.6 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.4 6.8 GO:0030515 snoRNA binding(GO:0030515)
0.4 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 2.5 GO:0031386 protein tag(GO:0031386)
0.3 4.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 15.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.3 3.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 4.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 4.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.3 2.7 GO:0015288 porin activity(GO:0015288)
0.3 6.0 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.3 27.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.3 14.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 28.0 GO:0051082 unfolded protein binding(GO:0051082)
0.3 24.4 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.3 2.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 3.7 GO:0005522 profilin binding(GO:0005522)
0.3 6.3 GO:0030332 cyclin binding(GO:0030332)
0.3 12.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.3 3.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.3 11.7 GO:0004527 exonuclease activity(GO:0004527)
0.2 1.2 GO:0036310 annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
0.2 3.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 2.4 GO:0019206 nucleoside kinase activity(GO:0019206)
0.2 81.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.2 3.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 4.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 3.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 1.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 7.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 4.6 GO:0017091 AU-rich element binding(GO:0017091)
0.2 0.8 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 11.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 1.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 7.3 GO:0050699 WW domain binding(GO:0050699)
0.2 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 7.2 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 2.7 GO:0050811 GABA receptor binding(GO:0050811)
0.2 13.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 1.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 1.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 4.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 7.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 55.9 GO:0005525 GTP binding(GO:0005525)
0.1 0.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 3.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 4.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 2.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 4.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 12.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.1 6.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 6.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 3.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 6.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 3.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 3.0 GO:0019239 deaminase activity(GO:0019239)
0.1 7.4 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 3.9 GO:0043621 protein self-association(GO:0043621)
0.1 5.8 GO:0043130 ubiquitin binding(GO:0043130)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.1 2.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 19.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.9 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.1 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 10.6 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 0.6 GO:0019213 deacetylase activity(GO:0019213)
0.1 2.4 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 5.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 9.4 GO:0051015 actin filament binding(GO:0051015)
0.1 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 8.3 GO:0008201 heparin binding(GO:0008201)
0.0 2.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.3 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 5.6 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 4.4 GO:0008083 growth factor activity(GO:0008083)
0.0 28.3 GO:0003723 RNA binding(GO:0003723)
0.0 1.5 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 1.0 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 51.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.9 57.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
1.9 49.5 PID ARF 3PATHWAY Arf1 pathway
1.8 51.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.7 69.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.6 24.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.3 67.3 PID AURORA A PATHWAY Aurora A signaling
1.2 50.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
1.0 54.2 PID IL1 PATHWAY IL1-mediated signaling events
0.9 30.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.8 58.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.8 2.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.7 12.0 PID MYC PATHWAY C-MYC pathway
0.6 29.9 PID AURORA B PATHWAY Aurora B signaling
0.6 33.1 PID PLK1 PATHWAY PLK1 signaling events
0.6 14.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.5 64.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.4 13.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.3 18.8 PID P53 REGULATION PATHWAY p53 pathway
0.3 12.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.3 12.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 6.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 7.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 14.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 5.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 13.9 PID P73PATHWAY p73 transcription factor network
0.1 12.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 6.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 4.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 5.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 145.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
3.6 83.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
3.0 75.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
2.9 41.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
2.8 79.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
2.2 42.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
2.2 177.8 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
2.1 201.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
2.0 30.5 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
1.6 13.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.6 14.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.5 44.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.5 21.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
1.5 16.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
1.5 41.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.3 41.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.3 34.7 REACTOME KINESINS Genes involved in Kinesins
1.3 13.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
1.3 19.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.3 11.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.3 25.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.1 17.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.1 15.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.1 66.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.1 30.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
1.0 15.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.9 15.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.9 19.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.9 8.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.8 36.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.8 25.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.8 12.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.8 30.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.7 19.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.7 19.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.7 5.7 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.7 23.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.7 11.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.7 51.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.7 19.1 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.6 20.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 20.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.6 12.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.5 44.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.5 19.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.5 7.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.5 4.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4 27.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.4 27.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 8.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.4 13.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 34.6 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.3 9.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 7.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.3 15.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 6.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 2.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.3 22.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 13.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 3.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 11.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 6.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 4.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 11.6 REACTOME S PHASE Genes involved in S Phase
0.2 9.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 3.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.2 2.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 7.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 5.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 3.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 19.9 REACTOME TRANSLATION Genes involved in Translation
0.1 2.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 3.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 1.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 6.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation