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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SIX5_SMARCC2_HCFC1

Z-value: 2.64

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
ENSG00000177045.6 SIX homeobox 5
ENSG00000139613.7 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
ENSG00000172534.9 host cell factor C1

Activity-expression correlation:

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_150754935 48.26 ENST00000297518.4
cyclin-dependent kinase 5
chr3_+_183892635 46.64 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
adaptor-related protein complex 2, mu 1 subunit
chr19_-_47354023 44.51 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
adaptor-related protein complex 2, sigma 1 subunit
chr11_-_82997371 42.20 ENST00000525503.1
coiled-coil domain containing 90B
chr15_+_40453204 41.25 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chrX_-_107334750 40.79 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr17_-_47492164 40.13 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
prohibitin
chr2_+_172544294 39.84 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
dynein, cytoplasmic 1, intermediate chain 2
chr19_-_47354082 39.36 ENST00000593442.1
ENST00000263270.6
adaptor-related protein complex 2, sigma 1 subunit
chr11_-_82997013 39.04 ENST00000529073.1
ENST00000529611.1
coiled-coil domain containing 90B
chr14_+_77924204 35.80 ENST00000555133.1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr11_-_82997420 35.61 ENST00000455220.2
ENST00000529689.1
coiled-coil domain containing 90B
chrX_-_107334790 34.65 ENST00000217958.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr2_+_63816295 33.84 ENST00000539945.1
ENST00000544381.1
malate dehydrogenase 1, NAD (soluble)
chr22_+_30163340 31.78 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr7_-_132766818 30.63 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_172544182 30.59 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
dynein, cytoplasmic 1, intermediate chain 2
chr14_+_77924373 30.51 ENST00000216479.3
ENST00000535854.2
ENST00000555517.1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr8_+_110346546 28.84 ENST00000521662.1
ENST00000521688.1
ENST00000520147.1
enhancer of yellow 2 homolog (Drosophila)
chr19_-_47551836 28.82 ENST00000253047.6
transmembrane protein 160
chr1_+_156024525 28.10 ENST00000368305.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr7_-_132766800 28.09 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_172543919 28.01 ENST00000452242.1
ENST00000340296.4
dynein, cytoplasmic 1, intermediate chain 2
chr2_+_172544011 27.93 ENST00000508530.1
dynein, cytoplasmic 1, intermediate chain 2
chr2_+_172543967 27.63 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
dynein, cytoplasmic 1, intermediate chain 2
chr14_+_97263641 27.14 ENST00000216639.3
vaccinia related kinase 1
chr11_+_16760161 26.92 ENST00000524439.1
ENST00000422258.2
ENST00000528634.1
ENST00000525684.1
chromosome 11 open reading frame 58
chr6_+_31633902 25.70 ENST00000375865.2
ENST00000375866.2
casein kinase 2, beta polypeptide
chr2_+_63816087 25.61 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
malate dehydrogenase 1, NAD (soluble)
chr1_+_155278539 25.48 ENST00000447866.1
farnesyl diphosphate synthase
chr10_-_104262426 25.42 ENST00000487599.1
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr11_-_134123142 25.13 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
thymocyte nuclear protein 1
chr1_+_224544572 24.79 ENST00000366857.5
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr6_-_5004241 24.59 ENST00000319533.5
ENST00000380051.2
ribonuclease P/MRP 40kDa subunit
chr19_-_54618650 24.48 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr22_-_41682172 24.47 ENST00000356244.3
Ran GTPase activating protein 1
chr1_+_156737292 24.01 ENST00000271526.4
ENST00000353233.3
papillary renal cell carcinoma (translocation-associated)
chr1_-_26233423 23.88 ENST00000357865.2
stathmin 1
chr10_-_104262460 23.72 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr1_+_156024552 23.59 ENST00000368304.5
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr19_-_54619006 23.59 ENST00000391759.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr1_+_155278625 23.36 ENST00000368356.4
ENST00000356657.6
farnesyl diphosphate synthase
chr1_+_224544552 23.27 ENST00000465271.1
ENST00000366858.3
cornichon family AMPA receptor auxiliary protein 4
chr20_-_62587735 23.15 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
uridine-cytidine kinase 1-like 1
chr19_-_42463418 22.91 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
Rab acceptor 1 (prenylated)
chr4_+_1723197 22.90 ENST00000485989.2
ENST00000313288.4
transforming, acidic coiled-coil containing protein 3
chr10_+_124913930 22.75 ENST00000368858.5
BUB3 mitotic checkpoint protein
chr3_-_98241358 22.50 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr12_-_56709786 21.69 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
Uncharacterized protein
canopy FGF signaling regulator 2
chr11_+_114310102 21.68 ENST00000265881.5
RNA exonuclease 2
chr20_+_62694461 21.20 ENST00000343484.5
ENST00000395053.3
transcription elongation factor A (SII), 2
chr6_+_31633833 21.12 ENST00000375882.2
ENST00000375880.2
casein kinase 2, beta polypeptide
Uncharacterized protein
chr3_-_98241760 21.01 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
claudin domain containing 1
chr19_-_1095330 20.37 ENST00000586746.1
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr17_-_21117902 20.33 ENST00000317635.5
transmembrane protein 11
chr13_-_31736027 20.30 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
heat shock 105kDa/110kDa protein 1
chr11_+_114310164 20.15 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr20_-_48732472 20.15 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
ubiquitin-conjugating enzyme E2 variant 1
chr12_-_56709674 19.60 ENST00000551286.1
ENST00000549318.1
canopy FGF signaling regulator 2
Uncharacterized protein
chr1_+_44440575 19.58 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr5_-_175815565 19.51 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16 nucleolar protein
chr17_-_46178741 19.27 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr11_-_65626753 19.24 ENST00000526975.1
ENST00000531413.1
cofilin 1 (non-muscle)
chr12_-_56710118 18.77 ENST00000273308.4
canopy FGF signaling regulator 2
chr17_-_46178527 18.74 ENST00000393408.3
chromobox homolog 1
chrX_-_48980098 18.66 ENST00000156109.5
G patch domain and KOW motifs
chr16_+_4674814 18.49 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr20_-_32891151 18.39 ENST00000217426.2
adenosylhomocysteinase
chr1_-_26232951 18.37 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr17_-_47492236 18.00 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
prohibitin
chr1_+_47799446 17.93 ENST00000371873.5
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr14_+_24702099 17.76 ENST00000420554.2
guanosine monophosphate reductase 2
chr11_+_114310237 17.61 ENST00000539119.1
RNA exonuclease 2
chr6_+_42981922 17.44 ENST00000326974.4
ENST00000244670.8
kelch domain containing 3
chr12_+_56546363 17.40 ENST00000551834.1
ENST00000552568.1
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr16_+_4674787 17.09 ENST00000262370.7
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr6_-_38670897 17.02 ENST00000373365.4
glyoxalase I
chr19_+_17416609 16.90 ENST00000602206.1
mitochondrial ribosomal protein L34
chr2_-_232646015 16.87 ENST00000287600.4
phosphodiesterase 6D, cGMP-specific, rod, delta
chrX_+_155110956 16.81 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
vesicle-associated membrane protein 7
chr19_+_6361754 16.75 ENST00000597326.1
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr7_-_100888337 16.74 ENST00000223136.4
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr10_+_124913793 16.70 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3 mitotic checkpoint protein
chr19_+_17416457 16.66 ENST00000252602.1
mitochondrial ribosomal protein L34
chr16_-_15149828 16.63 ENST00000566419.1
ENST00000568320.1
N-terminal asparagine amidase
chr19_-_2456922 16.57 ENST00000582871.1
ENST00000325327.3
lamin B2
chr20_+_30327063 16.47 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr3_+_169940153 16.37 ENST00000295797.4
protein kinase C, iota
chr6_-_110500905 16.31 ENST00000392587.2
WAS protein family, member 1
chr8_-_74884459 16.14 ENST00000522337.1
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr17_-_40950698 16.07 ENST00000328434.7
cytochrome c oxidase assembly factor 3
chr2_-_219134822 15.90 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr15_-_52861029 15.87 ENST00000561650.1
cAMP-regulated phosphoprotein, 19kDa
chr14_-_24701539 15.85 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr1_+_45205478 15.85 ENST00000452259.1
ENST00000372224.4
kinesin family member 2C
chr11_+_74660278 15.73 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_+_45205498 15.72 ENST00000372218.4
kinesin family member 2C
chr12_+_32832134 15.71 ENST00000452533.2
dynamin 1-like
chr11_-_47447767 15.71 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr14_+_24702127 15.57 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
guanosine monophosphate reductase 2
chr6_+_30875955 15.56 ENST00000259895.4
ENST00000539324.1
ENST00000376316.2
ENST00000453897.2
general transcription factor IIH, polypeptide 4, 52kDa
chr1_-_156710859 15.47 ENST00000361531.2
ENST00000412846.1
mitochondrial ribosomal protein L24
chr9_+_116037922 15.27 ENST00000374198.4
pre-mRNA processing factor 4
chr15_-_52861394 15.23 ENST00000563277.1
ENST00000566423.1
cAMP-regulated phosphoprotein, 19kDa
chr19_+_12917364 15.21 ENST00000221486.4
ribonuclease H2, subunit A
chr1_-_156710916 15.18 ENST00000368211.4
mitochondrial ribosomal protein L24
chr11_+_82783097 15.17 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30 antisense RNA 1 (head to head)
chr14_-_23398565 15.15 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
protein arginine methyltransferase 5
chr19_+_35225060 15.06 ENST00000599244.1
ENST00000392232.3
zinc finger protein 181
chr7_-_100888313 14.98 ENST00000442303.1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr3_+_158991025 14.94 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr1_-_36615051 14.81 ENST00000373163.1
trafficking protein particle complex 3
chr12_+_56546223 14.74 ENST00000550443.1
ENST00000207437.5
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr14_+_24702073 14.64 ENST00000399440.2
guanosine monophosphate reductase 2
chr19_+_1241732 14.34 ENST00000215375.2
ENST00000395633.1
ENST00000591660.1
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr1_-_36615065 14.33 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
trafficking protein particle complex 3
chr14_-_68141535 14.16 ENST00000554659.1
vesicle transport through interaction with t-SNAREs 1B
chr6_-_110501200 14.12 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WAS protein family, member 1
chr12_+_32832203 14.11 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
dynamin 1-like
chr12_+_93861282 14.10 ENST00000552217.1
ENST00000393128.4
ENST00000547098.1
mitochondrial ribosomal protein L42
chr12_+_93861264 14.08 ENST00000549982.1
ENST00000361630.2
mitochondrial ribosomal protein L42
chr6_+_88182643 14.04 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr10_+_111985713 14.03 ENST00000239007.7
MAX interactor 1, dimerization protein
chr15_-_52861323 14.01 ENST00000569723.1
ENST00000249822.4
ENST00000567669.1
ENST00000569281.2
ENST00000563566.1
ENST00000567830.1
cAMP-regulated phosphoprotein, 19kDa
chr1_-_10532531 13.96 ENST00000377036.2
ENST00000377038.3
DNA fragmentation factor, 45kDa, alpha polypeptide
chr8_-_63951730 13.84 ENST00000260118.6
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr21_-_15755446 13.77 ENST00000544452.1
ENST00000285667.3
heat shock protein 70kDa family, member 13
chr19_+_7600584 13.74 ENST00000600737.1
patatin-like phospholipase domain containing 6
chr14_+_24701819 13.73 ENST00000560139.1
ENST00000559910.1
guanosine monophosphate reductase 2
chrX_-_118986911 13.66 ENST00000276201.2
ENST00000345865.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr11_+_67374323 13.60 ENST00000322776.6
ENST00000532303.1
ENST00000532244.1
ENST00000528328.1
ENST00000529927.1
ENST00000532343.1
ENST00000415352.2
ENST00000533075.1
ENST00000529867.1
ENST00000530638.1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr20_+_62694590 13.59 ENST00000339217.4
transcription elongation factor A (SII), 2
chr3_-_167452298 13.54 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
programmed cell death 10
chr19_+_50354393 13.52 ENST00000391842.1
prostate tumor overexpressed 1
chr11_+_60681346 13.51 ENST00000227525.3
transmembrane protein 109
chr11_-_47447970 13.49 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr5_-_132112921 13.48 ENST00000378721.4
ENST00000378701.1
septin 8
chrX_+_77154935 13.44 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr14_+_24701628 13.42 ENST00000355299.4
ENST00000559836.1
guanosine monophosphate reductase 2
chr19_+_36705504 13.36 ENST00000456324.1
zinc finger protein 146
chr1_-_54304212 13.29 ENST00000540001.1
NDC1 transmembrane nucleoporin
chr2_-_99952769 13.26 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
thioredoxin domain containing 9
chr19_-_19030157 13.23 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
coatomer protein complex, subunit epsilon
chr18_-_43684186 13.22 ENST00000590406.1
ENST00000282050.2
ENST00000590324.1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr6_-_42981651 13.20 ENST00000244711.3
male-enhanced antigen 1
chr14_+_102430855 13.17 ENST00000360184.4
dynein, cytoplasmic 1, heavy chain 1
chr10_+_103892787 13.13 ENST00000278070.2
ENST00000413464.2
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr5_-_132112907 13.11 ENST00000458488.2
septin 8
chr14_-_68162464 13.01 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr5_+_85913721 12.99 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
cytochrome c oxidase subunit VIIc
chr1_-_54303934 12.94 ENST00000537333.1
NDC1 transmembrane nucleoporin
chr16_+_67881029 12.80 ENST00000569436.2
ENST00000568396.2
nuclear transport factor 2
chr20_-_47804894 12.69 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
staufen double-stranded RNA binding protein 1
chrX_+_47050236 12.53 ENST00000377351.4
ubiquitin-like modifier activating enzyme 1
chr3_-_167452703 12.52 ENST00000497056.2
ENST00000473645.2
programmed cell death 10
chr12_+_861717 12.44 ENST00000535572.1
WNK lysine deficient protein kinase 1
chr13_-_31736478 12.39 ENST00000445273.2
heat shock 105kDa/110kDa protein 1
chr4_+_174292058 12.32 ENST00000296504.3
Sin3A-associated protein, 30kDa
chr3_-_167452614 12.28 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
programmed cell death 10
chr2_-_170430277 12.27 ENST00000438035.1
ENST00000453929.2
FAST kinase domains 1
chr1_-_26232522 12.20 ENST00000399728.1
stathmin 1
chr12_+_12966250 12.16 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr5_-_132113559 12.15 ENST00000448933.1
septin 8
chr16_+_67880574 12.09 ENST00000219169.4
nuclear transport factor 2
chr19_+_50354430 12.03 ENST00000599732.1
prostate tumor overexpressed 1
chr12_-_57146095 11.96 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr8_-_99129338 11.86 ENST00000520507.1
heat-responsive protein 12
chr17_-_40075197 11.86 ENST00000590770.1
ENST00000590151.1
ATP citrate lyase
chrX_+_48334549 11.79 ENST00000019019.2
ENST00000348411.2
ENST00000396894.4
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr21_-_35288284 11.77 ENST00000290299.2
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr11_-_60674037 11.76 ENST00000541371.1
ENST00000227524.4
pre-mRNA processing factor 19
chr1_-_44820880 11.72 ENST00000372257.2
ENST00000457571.1
ENST00000452396.1
ERI1 exoribonuclease family member 3
chr5_+_5422778 11.71 ENST00000296564.7
KIAA0947
chr5_+_178286925 11.68 ENST00000322434.3
zinc finger protein 354B
chr7_+_135242652 11.60 ENST00000285968.6
ENST00000440390.2
nucleoporin 205kDa
chr17_-_26662440 11.55 ENST00000578122.1
intraflagellar transport 20 homolog (Chlamydomonas)
chr19_+_36236491 11.53 ENST00000591949.1
presenilin enhancer gamma secretase subunit
chr8_-_74884341 11.53 ENST00000284811.8
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
chr16_+_3074002 11.50 ENST00000326266.8
ENST00000574549.1
ENST00000575576.1
ENST00000253952.9
THO complex 6 homolog (Drosophila)
chr1_-_244615425 11.47 ENST00000366535.3
adenylosuccinate synthase
chr19_+_54619125 11.44 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
pre-mRNA processing factor 31
chr1_+_38158090 11.43 ENST00000373055.1
ENST00000327331.2
cell division cycle associated 8
chr18_+_60382672 11.39 ENST00000400316.4
ENST00000262719.5
PH domain and leucine rich repeat protein phosphatase 1
chr16_+_2097403 11.28 ENST00000219476.3
tuberous sclerosis 2
chr8_-_144699628 11.27 ENST00000529048.1
ENST00000529064.1
tissue specific transplantation antigen P35B
chr17_+_66243715 11.12 ENST00000359904.3
archaelysin family metallopeptidase 2
chr12_-_102455846 11.10 ENST00000545679.1
coiled-coil domain containing 53
chr7_+_140396946 11.09 ENST00000476470.1
ENST00000471136.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr7_+_128502871 10.99 ENST00000249289.4
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
chr5_+_118788138 10.95 ENST00000256216.6
hydroxysteroid (17-beta) dehydrogenase 4
chr1_+_151227179 10.94 ENST00000368884.3
ENST00000368881.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr2_-_203776864 10.93 ENST00000261015.4
WD repeat domain 12
chr1_+_38478378 10.90 ENST00000373014.4
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr19_-_50168962 10.74 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
interferon regulatory factor 3
chr2_+_242089833 10.72 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
protein phosphatase 1, regulatory subunit 7
chr1_-_155232221 10.68 ENST00000355379.3
secretory carrier membrane protein 3
chr6_-_52149475 10.62 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
minichromosome maintenance complex component 3
chr5_+_118788433 10.60 ENST00000414835.2
hydroxysteroid (17-beta) dehydrogenase 4
chr5_+_118788261 10.60 ENST00000504811.1
hydroxysteroid (17-beta) dehydrogenase 4
chr19_-_50169064 10.60 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
interferon regulatory factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 75.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
14.0 154.0 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
12.3 61.5 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
10.9 54.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
10.5 31.6 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
10.3 41.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
9.7 58.1 GO:2000323 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
8.7 43.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.3 41.4 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
8.0 48.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
7.1 35.6 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
7.1 56.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
7.1 21.3 GO:0042351 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
7.0 42.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
6.9 130.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
6.7 60.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
6.6 19.7 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
6.5 6.5 GO:0051781 positive regulation of cell division(GO:0051781)
6.4 6.4 GO:0006624 vacuolar protein processing(GO:0006624)
6.1 42.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
6.0 17.9 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
5.9 23.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
5.4 86.9 GO:0006107 oxaloacetate metabolic process(GO:0006107)
5.1 15.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
4.9 14.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
4.9 58.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
4.8 52.7 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
4.7 14.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
4.6 18.5 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
4.6 13.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
4.3 34.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
4.2 12.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
4.0 16.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
4.0 12.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
4.0 158.3 GO:0042407 cristae formation(GO:0042407)
3.9 27.1 GO:0090166 histone H3-S10 phosphorylation(GO:0043987) Golgi disassembly(GO:0090166)
3.9 23.1 GO:0044211 CTP salvage(GO:0044211)
3.8 11.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
3.8 15.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
3.8 30.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
3.7 25.7 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
3.6 43.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
3.5 35.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
3.5 10.4 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
3.4 17.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
3.4 20.5 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
3.4 17.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
3.3 13.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
3.2 22.6 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
3.0 17.9 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
3.0 17.8 GO:0048254 snoRNA localization(GO:0048254)
2.9 28.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
2.8 8.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
2.8 75.1 GO:0043101 purine-containing compound salvage(GO:0043101)
2.8 16.6 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
2.7 5.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
2.6 13.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.5 45.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
2.4 14.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
2.4 14.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
2.3 6.8 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
2.3 6.8 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
2.3 11.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
2.2 6.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
2.2 161.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
2.1 8.5 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
2.1 4.2 GO:0060348 bone development(GO:0060348)
2.1 6.3 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
2.1 8.4 GO:0031648 protein destabilization(GO:0031648)
2.1 14.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
2.0 24.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
2.0 4.0 GO:0031627 telomeric loop formation(GO:0031627)
1.9 18.6 GO:0042373 vitamin K metabolic process(GO:0042373)
1.8 16.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
1.8 5.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.8 21.3 GO:0039530 MDA-5 signaling pathway(GO:0039530)
1.8 12.4 GO:0016074 snoRNA metabolic process(GO:0016074)
1.8 8.8 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
1.7 5.0 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
1.6 8.0 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.6 30.5 GO:0031293 Notch receptor processing(GO:0007220) membrane protein intracellular domain proteolysis(GO:0031293)
1.6 39.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
1.6 4.7 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
1.5 1.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
1.5 49.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.4 44.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.4 14.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
1.4 18.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
1.4 4.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
1.4 4.2 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
1.4 19.3 GO:0051974 negative regulation of telomerase activity(GO:0051974)
1.3 46.7 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
1.3 4.0 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.3 5.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
1.3 48.0 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.3 27.2 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
1.3 3.8 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
1.3 12.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.3 3.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.3 26.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.3 12.6 GO:0043248 proteasome assembly(GO:0043248)
1.3 16.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
1.2 3.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
1.2 8.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.2 3.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
1.1 11.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.1 3.4 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.1 10.0 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.1 3.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
1.1 2.2 GO:0018126 protein hydroxylation(GO:0018126)
1.0 6.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.0 10.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.0 2.9 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.9 18.6 GO:0007005 mitochondrion organization(GO:0007005)
0.9 8.3 GO:0072718 response to cisplatin(GO:0072718)
0.9 9.1 GO:0051597 response to methylmercury(GO:0051597)
0.9 2.7 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.9 10.8 GO:0009642 response to light intensity(GO:0009642)
0.9 19.6 GO:0035855 megakaryocyte development(GO:0035855)
0.9 3.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.9 15.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.8 3.4 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.8 3.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072) negative regulation of protein kinase C signaling(GO:0090038)
0.8 3.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.8 2.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.8 2.5 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.8 5.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.8 2.4 GO:0009153 ADP biosynthetic process(GO:0006172) purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.8 2.4 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.8 4.0 GO:0006574 valine catabolic process(GO:0006574)
0.8 15.7 GO:0006465 signal peptide processing(GO:0006465)
0.8 3.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.8 1.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.8 11.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.8 7.6 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.8 3.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.8 162.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.7 3.0 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.7 47.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.7 33.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.7 3.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.7 2.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.7 7.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.7 2.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.7 15.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.7 0.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.7 9.0 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.7 6.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.7 3.3 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) dTTP metabolic process(GO:0046075)
0.6 1.9 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 7.6 GO:0006527 arginine catabolic process(GO:0006527)
0.6 4.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.6 8.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.6 0.6 GO:0040031 snRNA modification(GO:0040031)
0.6 9.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.6 9.3 GO:0045116 protein neddylation(GO:0045116)
0.6 7.4 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.6 33.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.6 40.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.6 18.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.6 4.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.6 3.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.6 8.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5 11.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.5 13.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.5 15.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 4.2 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.5 1.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.5 7.8 GO:0090344 negative regulation of cell aging(GO:0090344)
0.5 3.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.5 9.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.5 2.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 3.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.5 1.5 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.5 2.0 GO:1904753 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.5 4.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.5 32.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.5 7.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.5 1.4 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.5 4.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.4 0.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 5.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.4 21.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.4 5.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.4 6.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 8.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.4 9.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.4 4.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 3.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.4 9.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 4.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.4 11.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 2.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 2.9 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.4 1.4 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.3 12.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.3 4.8 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.3 10.3 GO:0006101 citrate metabolic process(GO:0006101)
0.3 14.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.3 7.7 GO:0001825 blastocyst formation(GO:0001825)
0.3 2.3 GO:0071554 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.3 5.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 2.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.3 13.5 GO:0006270 DNA replication initiation(GO:0006270)
0.3 10.1 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.3 2.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 5.0 GO:0031167 rRNA methylation(GO:0031167)
0.3 5.0 GO:0098792 xenophagy(GO:0098792)
0.3 1.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.3 4.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 1.2 GO:0019081 viral translation(GO:0019081) viral translational termination-reinitiation(GO:0075525)
0.3 5.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.3 1.7 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.3 0.9 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.3 15.6 GO:0006301 postreplication repair(GO:0006301)
0.3 4.8 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.3 7.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 8.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.3 7.5 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.3 7.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 1.5 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.2 1.5 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.2 2.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 17.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.2 1.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 1.2 GO:1903286 regulation of potassium ion import(GO:1903286)
0.2 0.6 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 12.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 15.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 4.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 2.9 GO:0016236 macroautophagy(GO:0016236)
0.2 0.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 10.6 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.2 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.4 GO:0050747 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 5.7 GO:0001504 neurotransmitter uptake(GO:0001504)
0.2 2.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 0.2 GO:1903513 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527) endoplasmic reticulum to cytosol transport(GO:1903513)
0.2 1.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.3 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.2 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 3.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 5.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 0.5 GO:0043307 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.2 2.8 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344)
0.2 0.6 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 1.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 1.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 0.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 2.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 3.6 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 3.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 13.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 4.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 5.7 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 16.7 GO:0000910 cytokinesis(GO:0000910)
0.1 0.7 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 4.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 4.1 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 3.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 0.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 3.5 GO:1901661 quinone metabolic process(GO:1901661)
0.1 12.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 2.6 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 0.4 GO:2001140 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.1 4.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 3.2 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1 1.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 38.5 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 1.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 4.0 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 2.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 1.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 6.0 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 2.4 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 3.7 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 0.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 1.6 GO:0048821 erythrocyte development(GO:0048821)
0.1 5.1 GO:0048678 response to axon injury(GO:0048678)
0.1 5.5 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 6.2 GO:0006310 DNA recombination(GO:0006310)
0.1 2.1 GO:0009409 response to cold(GO:0009409)
0.1 21.1 GO:0051260 protein homooligomerization(GO:0051260)
0.1 0.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.9 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.7 GO:0016180 snRNA processing(GO:0016180)
0.1 6.3 GO:0045471 response to ethanol(GO:0045471)
0.1 0.4 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.1 0.9 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.1 1.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 2.0 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.1 6.4 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.1 8.2 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 1.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 0.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 6.5 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 3.9 GO:0008380 RNA splicing(GO:0008380)
0.0 4.3 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 0.2 GO:0002887 negative regulation of immunoglobulin production(GO:0002638) negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) negative regulation of mast cell degranulation(GO:0043305)
0.0 4.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 5.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 2.5 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.6 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 2.2 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0 0.4 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.5 GO:0050770 regulation of axonogenesis(GO:0050770)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
13.1 39.4 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
12.5 75.1 GO:1902560 GMP reductase complex(GO:1902560)
12.1 48.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
11.2 78.5 GO:0061617 MICOS complex(GO:0061617)
10.5 31.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
10.3 51.7 GO:0071986 Ragulator complex(GO:0071986)
8.2 49.1 GO:0002177 manchette(GO:0002177)
7.6 38.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
7.6 38.0 GO:0001940 male pronucleus(GO:0001940)
7.6 37.8 GO:0035370 UBC13-UEV1A complex(GO:0035370)
7.3 51.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
6.8 129.1 GO:0036020 endolysosome membrane(GO:0036020)
6.4 121.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
5.5 166.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
5.2 15.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
5.1 20.5 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
4.9 19.7 GO:0031166 integral component of vacuolar membrane(GO:0031166)
4.8 14.5 GO:1902636 kinociliary basal body(GO:1902636)
4.6 13.7 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
4.1 24.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
4.0 39.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
3.8 15.3 GO:0071001 U4/U6 snRNP(GO:0071001)
3.8 22.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
3.8 41.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
3.6 50.0 GO:0031209 SCAR complex(GO:0031209)
3.5 10.6 GO:0031262 Ndc80 complex(GO:0031262)
3.3 36.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
3.1 36.8 GO:0030008 TRAPP complex(GO:0030008)
3.1 27.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
3.0 24.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
3.0 24.1 GO:0070552 BRISC complex(GO:0070552)
2.9 11.6 GO:0044611 nuclear pore inner ring(GO:0044611)
2.8 14.0 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
2.8 30.5 GO:0070765 gamma-secretase complex(GO:0070765)
2.6 105.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.6 20.7 GO:0032133 chromosome passenger complex(GO:0032133)
2.5 44.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
2.4 11.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
2.3 48.1 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
2.3 6.8 GO:0030689 Noc complex(GO:0030689)
2.3 6.8 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.2 15.7 GO:0005787 signal peptidase complex(GO:0005787)
2.2 9.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.2 20.0 GO:0005638 lamin filament(GO:0005638)
2.2 6.6 GO:0018444 translation release factor complex(GO:0018444)
2.2 19.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.1 4.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
2.0 32.1 GO:0016461 unconventional myosin complex(GO:0016461)
2.0 15.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.9 28.8 GO:0000124 SAGA complex(GO:0000124)
1.9 7.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.9 24.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.8 10.9 GO:0070545 PeBoW complex(GO:0070545)
1.8 26.4 GO:0045277 respiratory chain complex IV(GO:0045277)
1.6 11.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.6 6.4 GO:0070761 pre-snoRNP complex(GO:0070761)
1.6 9.5 GO:1990130 Iml1 complex(GO:1990130)
1.6 17.3 GO:0005686 U2 snRNP(GO:0005686)
1.5 16.5 GO:0043203 axon hillock(GO:0043203)
1.5 8.8 GO:0071817 MMXD complex(GO:0071817)
1.5 14.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.4 11.4 GO:0005687 U4 snRNP(GO:0005687)
1.3 43.1 GO:0005640 nuclear outer membrane(GO:0005640)
1.3 9.3 GO:0016272 prefoldin complex(GO:0016272)
1.3 13.2 GO:0030126 COPI vesicle coat(GO:0030126)
1.3 7.9 GO:0072589 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.3 10.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.3 31.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.3 15.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.3 16.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.2 33.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
1.2 6.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
1.2 34.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.1 12.3 GO:0005869 dynactin complex(GO:0005869)
1.1 7.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.1 4.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.1 6.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.0 3.1 GO:0071159 NF-kappaB complex(GO:0071159)
1.0 5.2 GO:0033263 CORVET complex(GO:0033263)
1.0 18.4 GO:0034709 methylosome(GO:0034709)
1.0 7.1 GO:0030870 Mre11 complex(GO:0030870)
1.0 5.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
1.0 7.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
1.0 4.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.0 16.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.0 34.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.9 23.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.9 63.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.8 20.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.8 45.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.8 47.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.8 5.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 5.5 GO:0032009 early phagosome(GO:0032009)
0.7 41.5 GO:0005871 kinesin complex(GO:0005871)
0.7 5.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.7 2.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.7 16.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.7 2.7 GO:0055087 Ski complex(GO:0055087)
0.7 3.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.7 2.6 GO:0070876 SOSS complex(GO:0070876)
0.6 1.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 1.9 GO:0043224