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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SMAD1

Z-value: 3.91

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Transcription factors associated with SMAD1

Gene Symbol Gene ID Gene Info
ENSG00000170365.5 SMAD family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD1hg19_v2_chr4_+_146402925_146402957-0.522.0e-16Click!

Activity profile of SMAD1 motif

Sorted Z-values of SMAD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106209368 116.24 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_33048483 99.78 ENST00000419277.1
major histocompatibility complex, class II, DP alpha 1
chr14_-_106111127 78.25 ENST00000390545.2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr14_-_106237742 67.27 ENST00000390551.2
immunoglobulin heavy constant gamma 3 (G3m marker)
chr21_-_46330545 66.19 ENST00000320216.6
ENST00000397852.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_106092403 65.38 ENST00000390543.2
immunoglobulin heavy constant gamma 4 (G4m marker)
chr6_+_33043703 62.62 ENST00000418931.2
ENST00000535465.1
major histocompatibility complex, class II, DP beta 1
chr6_+_33048222 58.98 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chr16_+_222846 51.56 ENST00000251595.6
ENST00000397806.1
hemoglobin, alpha 2
chr19_+_39897453 48.41 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
ZFP36 ring finger protein
chr11_-_5248294 45.37 ENST00000335295.4
hemoglobin, beta
chrX_-_107018969 45.03 ENST00000372383.4
TSC22 domain family, member 3
chr19_+_49838653 43.46 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr22_+_23264766 42.79 ENST00000390331.2
immunoglobulin lambda constant 7
chr22_+_23247030 42.28 ENST00000390324.2
immunoglobulin lambda joining 3
chr2_+_90077680 42.12 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr2_-_89310012 39.67 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr22_+_23241661 38.14 ENST00000390322.2
immunoglobulin lambda joining 2
chr18_+_74240610 37.06 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr22_+_23040274 36.85 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr22_+_23237555 35.00 ENST00000390321.2
immunoglobulin lambda constant 1 (Mcg marker)
chr16_-_55866997 34.79 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr6_+_31583761 34.67 ENST00000376049.4
allograft inflammatory factor 1
chrX_-_107019181 34.59 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr2_+_90139056 33.54 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr22_-_19512893 33.29 ENST00000403084.1
ENST00000413119.2
claudin 5
chr9_+_139871948 32.43 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
prostaglandin D2 synthase 21kDa (brain)
chr19_+_1065922 32.38 ENST00000539243.2
histocompatibility (minor) HA-1
chr22_+_23243156 32.33 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr17_+_38083977 31.28 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr22_-_45559642 31.17 ENST00000426282.2
CTA-217C2.1
chr6_+_32709119 30.99 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr1_-_31230650 29.30 ENST00000294507.3
lysosomal protein transmembrane 5
chr9_+_139874683 29.24 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr6_+_32605195 29.24 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr3_-_138763734 29.16 ENST00000413199.1
ENST00000502927.2
proline rich 23C
chr18_+_77439775 28.62 ENST00000299543.7
ENST00000075430.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr14_-_106054659 28.34 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr2_-_89292422 27.91 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_22707260 27.67 ENST00000390293.1
immunoglobulin lambda variable 5-48 (non-functional)
chr6_-_31550192 27.53 ENST00000429299.2
ENST00000446745.2
lymphotoxin beta (TNF superfamily, member 3)
chr11_+_121461097 26.84 ENST00000527934.1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_-_51529849 26.42 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
kallikrein-related peptidase 11
chr19_-_54784353 26.13 ENST00000391746.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr2_-_89399845 25.97 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr22_+_23134974 25.89 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr19_-_17185848 25.85 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chr22_-_27620603 25.84 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr17_-_29641084 25.74 ENST00000544462.1
ecotropic viral integration site 2B
chr19_+_55141948 25.72 ENST00000396332.4
ENST00000427581.2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr16_+_226658 25.65 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr4_+_76439665 25.15 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP domain containing 6
chr16_+_66914264 25.13 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr6_-_31239846 24.74 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
major histocompatibility complex, class I, C
chr9_+_139873264 24.64 ENST00000446677.1
prostaglandin D2 synthase 21kDa (brain)
chr18_-_47813940 24.62 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC finger protein 1
chr19_+_42381173 24.53 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr3_-_39322728 24.52 ENST00000541347.1
ENST00000412814.1
chemokine (C-X3-C motif) receptor 1
chr19_-_16582815 23.94 ENST00000455140.2
ENST00000248070.6
ENST00000594975.1
epidermal growth factor receptor pathway substrate 15-like 1
chr22_+_23101182 23.68 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr19_+_52901094 23.63 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
zinc finger protein 528
chr22_+_23229960 23.51 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
immunoglobulin lambda-like polypeptide 5
chr19_-_6690723 23.49 ENST00000601008.1
complement component 3
chr22_+_23165153 23.45 ENST00000390317.2
immunoglobulin lambda variable 2-8
chr4_-_1166954 23.30 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
spondin 2, extracellular matrix protein
chr2_-_99224915 23.27 ENST00000328709.3
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr4_+_128554081 23.23 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr16_+_3115323 22.79 ENST00000531965.1
ENST00000396887.3
ENST00000529699.1
ENST00000526464.2
ENST00000440815.3
interleukin 32
chr6_-_74161977 22.62 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chr11_-_2323290 22.58 ENST00000381153.3
chromosome 11 open reading frame 21
chr2_-_87017985 22.48 ENST00000352580.3
CD8a molecule
chr2_+_241564655 22.37 ENST00000407714.1
G protein-coupled receptor 35
chr11_+_1891380 22.35 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr3_+_156544057 22.23 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr9_-_97401782 22.16 ENST00000375326.4
fructose-1,6-bisphosphatase 1
chr14_-_106174960 21.92 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr22_+_23077065 21.88 ENST00000390310.2
immunoglobulin lambda variable 2-18
chr2_-_89278535 21.84 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr1_-_204380919 21.75 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr5_-_172198190 21.71 ENST00000239223.3
dual specificity phosphatase 1
chr11_+_2323349 21.47 ENST00000381121.3
tetraspanin 32
chr2_-_89513402 21.44 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr3_-_46506563 21.42 ENST00000231751.4
lactotransferrin
chr16_+_3115298 21.41 ENST00000325568.5
ENST00000534507.1
interleukin 32
chr19_-_51875894 21.38 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr19_+_42381337 21.37 ENST00000597454.1
ENST00000444740.2
CD79a molecule, immunoglobulin-associated alpha
chr13_-_30881621 21.31 ENST00000380615.3
katanin p60 subunit A-like 1
chr22_+_22681656 21.17 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr16_+_3115378 21.04 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
interleukin 32
chr16_+_30483962 20.87 ENST00000356798.6
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr19_+_1067271 20.86 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr19_+_1077393 20.81 ENST00000590577.1
histocompatibility (minor) HA-1
chrX_+_70586140 20.79 ENST00000276072.3
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr1_+_152635854 20.75 ENST00000368784.1
late cornified envelope 2D
chr19_+_16435625 20.70 ENST00000248071.5
ENST00000592003.1
Kruppel-like factor 2
chr5_-_131826457 20.59 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr6_+_31582961 20.50 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr11_+_695614 20.47 ENST00000608174.1
ENST00000397512.3
transmembrane protein 80
chr17_-_29641104 20.35 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr7_-_150038704 20.33 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
retinoic acid receptor responder (tazarotene induced) 2
chr11_+_695787 20.16 ENST00000526170.1
ENST00000488769.1
transmembrane protein 80
chr15_+_89181974 20.03 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr4_-_681114 19.99 ENST00000503156.1
major facilitator superfamily domain containing 7
chr2_-_87018784 19.97 ENST00000283635.3
ENST00000538832.1
CD8a molecule
chr2_-_11272234 19.76 ENST00000590207.1
ENST00000417697.2
ENST00000396164.1
ENST00000536743.1
ENST00000544306.1
AC062028.1
chr17_-_80275417 19.71 ENST00000583376.1
ENST00000578509.1
ENST00000584284.1
ENST00000582480.1
CD7 molecule
chr3_+_183967409 19.52 ENST00000324557.4
ENST00000402825.3
endothelin converting enzyme 2
chr3_+_45071622 19.45 ENST00000428034.1
C-type lectin domain family 3, member B
chr4_-_1166623 19.42 ENST00000290902.5
spondin 2, extracellular matrix protein
chr15_+_75074410 19.33 ENST00000439220.2
c-src tyrosine kinase
chr19_-_12662240 19.30 ENST00000416136.1
ENST00000428311.1
zinc finger protein 564
ZNF709
chr17_-_40021656 19.10 ENST00000319121.3
kelch-like family member 11
chr2_-_89521942 19.07 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr16_+_30484021 18.99 ENST00000358164.5
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr12_+_6898638 18.99 ENST00000011653.4
CD4 molecule
chr10_+_38299546 18.84 ENST00000374618.3
ENST00000432900.2
ENST00000458705.2
ENST00000469037.2
zinc finger protein 33A
chr17_-_79269067 18.75 ENST00000288439.5
ENST00000374759.3
solute carrier family 38, member 10
chr1_+_28206150 18.73 ENST00000456990.1
thymocyte selection associated family member 2
chr12_+_7055631 18.72 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chr17_+_34431212 18.70 ENST00000394495.1
chemokine (C-C motif) ligand 4
chr17_-_37844267 18.68 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
post-GPI attachment to proteins 3
chr2_-_89340242 18.67 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr11_-_66360548 18.63 ENST00000333861.3
coiled-coil domain containing 87
chr5_+_54398463 18.54 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr19_-_6481776 18.46 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENN/MADD domain containing 1C
chr2_+_89923550 18.46 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chrX_-_19002696 18.46 ENST00000379942.4
phosphorylase kinase, alpha 2 (liver)
chr13_+_25338290 18.38 ENST00000255324.5
ENST00000381921.1
ENST00000255325.6
ring finger protein 17
chr3_+_153839149 18.32 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr20_-_23066953 18.29 ENST00000246006.4
CD93 molecule
chr3_+_40566369 18.20 ENST00000403205.2
ENST00000310898.1
ENST00000339296.5
ENST00000431278.1
zinc finger protein 621
chr2_-_89442621 18.14 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr17_+_77681075 18.08 ENST00000397549.2
CTD-2116F7.1
chr1_+_153330322 17.97 ENST00000368738.3
S100 calcium binding protein A9
chr7_+_100136811 17.96 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr15_+_81589254 17.94 ENST00000394652.2
interleukin 16
chr2_+_89901292 17.92 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr11_-_18034701 17.91 ENST00000265965.5
secretion regulating guanine nucleotide exchange factor
chr19_+_45973120 17.87 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr2_-_89459813 17.86 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr11_+_1889880 17.83 ENST00000405957.2
lymphocyte-specific protein 1
chr1_-_27961720 17.83 ENST00000545953.1
ENST00000374005.3
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr19_-_51587502 17.82 ENST00000156499.2
ENST00000391802.1
kallikrein-related peptidase 14
chr21_-_46340770 17.74 ENST00000397854.3
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_169725231 17.74 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_67205538 17.68 ENST00000326294.3
protein tyrosine phosphatase, receptor type, C-associated protein
chr1_-_161600990 17.56 ENST00000531221.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr16_-_55867146 17.42 ENST00000422046.2
carboxylesterase 1
chr19_-_16582754 17.42 ENST00000602151.1
ENST00000597937.1
ENST00000535753.2
epidermal growth factor receptor pathway substrate 15-like 1
chr14_-_107083690 17.31 ENST00000455737.1
ENST00000390629.2
immunoglobulin heavy variable 4-59
chr11_+_124492749 17.23 ENST00000531667.1
ENST00000441174.3
ENST00000375005.4
transforming growth factor beta regulator 1
chr19_+_859425 17.21 ENST00000327726.6
complement factor D (adipsin)
chr19_-_36231437 17.18 ENST00000591748.1
IGF-like family receptor 1
chr1_-_52831796 17.17 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
coiled-coil and C2 domain containing 1B
chr4_-_156875003 17.12 ENST00000433477.3
cathepsin O
chr17_-_62009621 17.12 ENST00000349817.2
ENST00000392795.3
CD79b molecule, immunoglobulin-associated beta
chr1_+_32739733 17.09 ENST00000333070.4
lymphocyte-specific protein tyrosine kinase
chr2_+_131113609 17.08 ENST00000347849.3
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr11_+_2421718 17.03 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
tumor suppressing subtransferable candidate 4
chr9_+_134378289 16.99 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
protein-O-mannosyltransferase 1
chr14_-_94854926 16.93 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr21_-_46340884 16.87 ENST00000302347.5
ENST00000517819.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_106322288 16.82 ENST00000390559.2
immunoglobulin heavy constant mu
chr1_+_16767167 16.76 ENST00000337132.5
NECAP endocytosis associated 2
chr16_-_30032610 16.72 ENST00000574405.1
double C2-like domains, alpha
chr14_-_106692191 16.69 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr6_-_159420780 16.67 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chr2_-_128568721 16.63 ENST00000322313.4
ENST00000393006.1
ENST00000409658.3
ENST00000436787.1
WD repeat domain 33
chr2_+_90108504 16.62 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_89999259 16.62 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr17_-_62009702 16.60 ENST00000006750.3
CD79b molecule, immunoglobulin-associated beta
chr2_-_89266286 16.59 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr2_+_85921522 16.57 ENST00000409696.3
granulysin
chr17_-_62084241 16.49 ENST00000449662.2
intercellular adhesion molecule 2
chr19_-_36643329 16.48 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr19_-_36297632 16.46 ENST00000588266.2
proline dehydrogenase (oxidase) 2
chr9_-_97402413 16.42 ENST00000414122.1
fructose-1,6-bisphosphatase 1
chr7_+_73623717 16.35 ENST00000344995.5
ENST00000460943.1
linker for activation of T cells family, member 2
chrX_+_70586082 16.32 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr16_-_25122785 16.31 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
chr5_+_157170703 16.30 ENST00000286307.5
LSM11, U7 small nuclear RNA associated
chr14_-_81687197 16.26 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr2_-_89619904 16.20 ENST00000498574.1
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr11_+_2323236 16.19 ENST00000182290.4
tetraspanin 32
chr6_-_31324943 16.18 ENST00000412585.2
ENST00000434333.1
major histocompatibility complex, class I, B
chr17_-_80275466 16.18 ENST00000312648.3
CD7 molecule
chr17_-_71410794 16.17 ENST00000424778.1
sidekick cell adhesion molecule 2
chr6_+_29691198 16.11 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr7_+_26438187 16.10 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr19_+_45417921 16.06 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr17_-_62097927 16.06 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr5_-_149492904 16.03 ENST00000286301.3
ENST00000511344.1
colony stimulating factor 1 receptor
chr19_+_15752088 16.03 ENST00000585846.1
cytochrome P450, family 4, subfamily F, polypeptide 3
chr1_-_38157877 16.02 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
chromosome 1 open reading frame 109
chr11_+_71927807 16.01 ENST00000298223.6
ENST00000454954.2
ENST00000541003.1
ENST00000539412.1
ENST00000536778.1
ENST00000535625.1
ENST00000321324.7
folate receptor 2 (fetal)
chr19_-_58326267 16.01 ENST00000391701.1
zinc finger protein 552
chr17_-_41465674 15.97 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
long intergenic non-protein coding RNA 910
chr19_+_50922187 15.95 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
Spi-B transcription factor (Spi-1/PU.1 related)
chr2_-_158345462 15.87 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr11_-_73694346 15.85 ENST00000310473.3
uncoupling protein 2 (mitochondrial, proton carrier)

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
17.0 68.1 GO:0030185 nitric oxide transport(GO:0030185)
16.5 49.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
15.9 47.8 GO:1900159 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
13.7 54.8 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
13.1 39.4 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
13.0 38.9 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
12.8 38.3 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
12.6 50.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
12.3 61.7 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
12.2 36.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
11.8 94.2 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
11.1 44.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
10.8 43.4 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
10.7 42.9 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
10.6 21.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
10.6 95.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
10.3 51.7 GO:0036369 transcription factor catabolic process(GO:0036369)
10.2 724.7 GO:0006910 phagocytosis, recognition(GO:0006910)
10.1 10.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
10.0 30.1 GO:0002818 intracellular defense response(GO:0002818)
9.5 28.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
9.4 9.4 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308)
9.2 9.2 GO:0035878 nail development(GO:0035878)
8.8 26.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
8.5 51.1 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
8.5 17.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
8.5 25.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
8.4 25.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
8.3 41.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
8.2 33.0 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
8.1 24.4 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
8.1 24.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
7.9 31.8 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
7.7 7.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
7.6 60.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
7.6 45.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
7.4 44.1 GO:0070560 protein secretion by platelet(GO:0070560)
7.3 43.8 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
7.2 43.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
7.2 21.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
7.1 21.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
7.1 141.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
7.0 7.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
6.9 20.6 GO:0061760 antifungal innate immune response(GO:0061760)
6.8 6.8 GO:0070666 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
6.6 616.4 GO:0006958 complement activation, classical pathway(GO:0006958)
6.4 6.4 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
6.4 19.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
6.3 19.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
6.3 50.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
6.3 31.3 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
6.0 18.0 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
5.9 5.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
5.8 17.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
5.7 17.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
5.7 17.1 GO:1903413 cellular response to bile acid(GO:1903413)
5.7 51.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
5.6 5.6 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
5.6 22.5 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
5.6 5.6 GO:0006000 fructose metabolic process(GO:0006000) fructose 1,6-bisphosphate metabolic process(GO:0030388)
5.6 27.8 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
5.4 21.7 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
5.4 5.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
5.4 21.5 GO:0015942 formate metabolic process(GO:0015942)
5.3 26.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
5.3 26.4 GO:0010813 neuropeptide catabolic process(GO:0010813)
5.2 10.4 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
5.2 15.6 GO:0071529 cementum mineralization(GO:0071529)
5.2 5.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
5.1 10.1 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
5.0 15.0 GO:1904316 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
4.9 24.6 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
4.9 29.3 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
4.9 14.6 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
4.8 4.8 GO:0007435 salivary gland morphogenesis(GO:0007435)
4.8 19.3 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
4.8 86.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
4.8 23.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
4.7 47.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
4.7 14.1 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
4.7 23.4 GO:0072144 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
4.7 4.7 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
4.6 64.2 GO:0015671 oxygen transport(GO:0015671)
4.6 13.7 GO:0060018 astrocyte fate commitment(GO:0060018)
4.5 4.5 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
4.5 13.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
4.3 52.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
4.3 12.9 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
4.3 17.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
4.3 29.8 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
4.2 16.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
4.2 12.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.1 20.6 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
4.1 8.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
4.1 4.1 GO:0043968 histone H2A acetylation(GO:0043968)
4.1 12.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
4.0 16.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
4.0 12.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
4.0 12.0 GO:1990502 dense core granule maturation(GO:1990502)
4.0 15.9 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
4.0 4.0 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
3.9 3.9 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
3.9 3.9 GO:0048807 female genitalia morphogenesis(GO:0048807)
3.9 55.0 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
3.9 11.6 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
3.9 19.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
3.8 19.0 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
3.8 11.3 GO:0043366 beta selection(GO:0043366)
3.7 11.2 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
3.7 22.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
3.7 11.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
3.7 18.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
3.6 21.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
3.6 25.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
3.6 25.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
3.6 10.7 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
3.6 21.3 GO:0051013 microtubule severing(GO:0051013)
3.5 17.7 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
3.5 10.6 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
3.5 7.0 GO:0006258 UDP-glucose catabolic process(GO:0006258)
3.5 10.5 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
3.5 10.4 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
3.5 13.9 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
3.5 3.5 GO:0046113 nucleobase catabolic process(GO:0046113)
3.5 6.9 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
3.4 13.7 GO:0048749 compound eye development(GO:0048749)
3.4 379.7 GO:0031295 T cell costimulation(GO:0031295)
3.3 6.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
3.3 19.9 GO:0030035 microspike assembly(GO:0030035)
3.3 16.6 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
3.3 19.8 GO:0018095 protein polyglutamylation(GO:0018095)
3.3 3.3 GO:0032606 regulation of type I interferon production(GO:0032479) type I interferon production(GO:0032606)
3.3 13.2 GO:0018094 protein polyglycylation(GO:0018094)
3.3 16.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
3.2 6.5 GO:0002088 lens development in camera-type eye(GO:0002088)
3.2 6.4 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
3.2 3.2 GO:0009896 positive regulation of catabolic process(GO:0009896)
3.2 25.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
3.2 3.2 GO:0060594 mammary gland specification(GO:0060594)
3.1 6.3 GO:0002384 hepatic immune response(GO:0002384)
3.1 9.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
3.1 6.3 GO:0001810 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
3.1 6.2 GO:0070543 response to linoleic acid(GO:0070543)
3.1 9.3 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
3.1 12.4 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
3.1 18.6 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
3.1 30.9 GO:1990403 embryonic brain development(GO:1990403)
3.1 9.3 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
3.1 6.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
3.1 30.7 GO:0032074 negative regulation of nuclease activity(GO:0032074)
3.1 9.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
3.0 9.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
3.0 18.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
3.0 18.2 GO:0015811 L-cystine transport(GO:0015811)
3.0 15.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
3.0 24.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
3.0 9.0 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
3.0 9.0 GO:1902490 regulation of sperm capacitation(GO:1902490)
3.0 12.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
3.0 6.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
3.0 23.9 GO:0015705 iodide transport(GO:0015705)
3.0 23.8 GO:0006013 mannose metabolic process(GO:0006013)
3.0 5.9 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
3.0 11.8 GO:0032053 ciliary basal body organization(GO:0032053)
2.9 2.9 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
2.9 8.8 GO:1904430 negative regulation of t-circle formation(GO:1904430)
2.9 2.9 GO:0010755 regulation of plasminogen activation(GO:0010755)
2.9 11.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
2.9 14.6 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
2.9 5.8 GO:0098780 macromitophagy(GO:0000423) response to mitochondrial depolarisation(GO:0098780)
2.9 8.7 GO:0070842 aggresome assembly(GO:0070842)
2.9 59.9 GO:0048730 epidermis morphogenesis(GO:0048730)
2.8 28.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
2.8 8.5 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
2.8 11.3 GO:0051866 general adaptation syndrome(GO:0051866)
2.8 11.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
2.8 11.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.8 19.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.8 2.8 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
2.8 8.3 GO:0010332 response to gamma radiation(GO:0010332)
2.7 2.7 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
2.7 5.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.7 5.4 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.7 8.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
2.7 10.8 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
2.7 8.1 GO:0007341 penetration of zona pellucida(GO:0007341)
2.7 5.4 GO:0071224 positive regulation of immature T cell proliferation(GO:0033091) cellular response to peptidoglycan(GO:0071224)
2.7 2.7 GO:0046487 glyoxylate metabolic process(GO:0046487)
2.7 10.7 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
2.7 5.4 GO:0002266 follicular dendritic cell activation(GO:0002266)
2.7 18.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
2.7 42.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
2.7 24.0 GO:0090197 positive regulation of chemokine secretion(GO:0090197)
2.7 8.0 GO:1902988 neurofibrillary tangle assembly(GO:1902988)
2.7 13.3 GO:0071554 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
2.6 7.9 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
2.6 10.5 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
2.6 2.6 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
2.6 10.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
2.6 2.6 GO:0035963 cellular response to interleukin-13(GO:0035963)
2.6 10.4 GO:0001825 blastocyst formation(GO:0001825)
2.6 20.9 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
2.6 2.6 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.6 10.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
2.6 53.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
2.6 15.3 GO:0021523 somatic motor neuron differentiation(GO:0021523)
2.5 5.0 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
2.5 10.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
2.5 65.4 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
2.5 20.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.5 15.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
2.5 125.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
2.5 10.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.5 15.0 GO:0042133 neurotransmitter metabolic process(GO:0042133)
2.5 7.5 GO:0010828 positive regulation of glucose transport(GO:0010828)
2.5 5.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
2.5 9.9 GO:0030279 negative regulation of ossification(GO:0030279)
2.5 2.5 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
2.5 2.5 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
2.5 4.9 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
2.5 14.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
2.4 7.3 GO:0015680 intracellular copper ion transport(GO:0015680)
2.4 4.9 GO:0072237 metanephric proximal tubule development(GO:0072237)
2.4 79.9 GO:0006536 glutamate metabolic process(GO:0006536)
2.4 4.8 GO:0046110 xanthine metabolic process(GO:0046110)
2.4 7.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
2.4 4.8 GO:0002027 regulation of heart rate(GO:0002027)
2.4 4.8 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
2.4 23.9 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
2.4 12.0 GO:0046968 peptide antigen transport(GO:0046968)
2.4 4.8 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.4 7.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.4 19.1 GO:0006116 NADH oxidation(GO:0006116)
2.4 9.5 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
2.4 16.6 GO:0006102 isocitrate metabolic process(GO:0006102)
2.4 7.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
2.3 7.0 GO:0097359 UDP-glucosylation(GO:0097359)
2.3 2.3 GO:0032571 response to vitamin K(GO:0032571)
2.3 2.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
2.3 2.3 GO:0030317 sperm motility(GO:0030317)
2.3 7.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
2.3 9.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
2.3 16.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
2.3 6.9 GO:0045918 negative regulation of cytolysis(GO:0045918)
2.3 6.9 GO:2000870 regulation of progesterone secretion(GO:2000870)
2.3 9.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
2.3 16.0 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
2.3 6.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
2.3 6.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
2.3 9.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.3 9.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.3 6.8 GO:1904529 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
2.2 2.2 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
2.2 13.4 GO:0006477 protein sulfation(GO:0006477)
2.2 15.6 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
2.2 15.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
2.2 28.7 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
2.2 4.4 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826) negative regulation of T-helper 1 cell differentiation(GO:0045626)
2.2 6.6 GO:0008355 olfactory learning(GO:0008355)
2.2 6.6 GO:0003218 cardiac left ventricle formation(GO:0003218) cell migration involved in vasculogenesis(GO:0035441)
2.2 8.8 GO:0009450 gamma-aminobutyric acid biosynthetic process(GO:0009449) gamma-aminobutyric acid catabolic process(GO:0009450) negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
2.2 11.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
2.2 2.2 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
2.2 4.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.2 13.0 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
2.2 10.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.2 43.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
2.1 6.4 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
2.1 10.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.1 6.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
2.1 10.7 GO:0050808 synapse organization(GO:0050808)
2.1 17.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
2.1 12.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
2.1 6.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
2.1 27.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
2.1 2.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
2.1 21.1 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
2.1 8.4 GO:0006929 substrate-dependent cell migration(GO:0006929)
2.1 21.0 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
2.1 6.3 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
2.1 18.8 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
2.1 6.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
2.1 4.1 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
2.1 6.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
2.1 35.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
2.1 2.1 GO:0009233 menaquinone metabolic process(GO:0009233)
2.0 6.1 GO:0001694 histamine biosynthetic process(GO:0001694)
2.0 16.4 GO:1903416 response to glycoside(GO:1903416)
2.0 12.3 GO:0001661 conditioned taste aversion(GO:0001661)
2.0 8.2 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
2.0 6.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
2.0 12.2 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
2.0 14.2 GO:0006772 thiamine metabolic process(GO:0006772)
2.0 4.0 GO:0008045 motor neuron axon guidance(GO:0008045)
2.0 16.1 GO:0007506 gonadal mesoderm development(GO:0007506)
2.0 4.0 GO:0019233 sensory perception of pain(GO:0019233)
2.0 16.0 GO:0019370 leukotriene biosynthetic process(GO:0019370)
2.0 4.0 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
2.0 12.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.0 12.0 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
2.0 9.9 GO:0006041 glucosamine metabolic process(GO:0006041)
2.0 59.1 GO:0045730 respiratory burst(GO:0045730)
2.0 19.7 GO:0019835 cytolysis(GO:0019835)
2.0 9.8 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
2.0 5.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
2.0 2.0 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
1.9 13.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.9 5.8 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.9 7.8 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
1.9 15.4 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.9 5.8 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
1.9 19.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.9 246.6 GO:0002377 immunoglobulin production(GO:0002377)
1.9 13.4 GO:0045007 depurination(GO:0045007)
1.9 1.9 GO:0035962 response to interleukin-13(GO:0035962)
1.9 20.9 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.9 3.8 GO:0035995 detection of muscle stretch(GO:0035995)
1.9 13.2 GO:0042426 choline catabolic process(GO:0042426)
1.9 7.5 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.9 7.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.9 26.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
1.9 18.5 GO:0010002 cardioblast differentiation(GO:0010002)
1.9 3.7 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.8 1.8 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
1.8 5.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
1.8 11.0 GO:0072719 cellular response to cisplatin(GO:0072719)
1.8 1.8 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
1.8 5.5 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.8 36.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
1.8 1.8 GO:0007635 chemosensory behavior(GO:0007635)
1.8 5.4 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
1.8 9.0 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
1.8 18.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
1.8 5.4 GO:0036090 cleavage furrow ingression(GO:0036090)
1.8 3.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.8 9.0 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.8 7.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
1.8 21.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.8 3.6 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.8 10.6 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
1.8 7.1 GO:0042335 cuticle development(GO:0042335)
1.7 28.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
1.7 5.2 GO:0032847 regulation of cellular pH reduction(GO:0032847)
1.7 6.9 GO:0018377 protein myristoylation(GO:0018377)
1.7 8.6 GO:0060017 parathyroid gland development(GO:0060017)
1.7 12.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
1.7 6.8 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
1.7 3.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
1.7 5.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
1.7 6.7 GO:0042713 sperm ejaculation(GO:0042713)
1.7 5.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.7 6.6 GO:0009822 alkaloid catabolic process(GO:0009822)
1.7 9.9 GO:0007258 JUN phosphorylation(GO:0007258)
1.6 4.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.6 9.9 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.6 4.9 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.6 21.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.6 13.1 GO:0070995 NADPH oxidation(GO:0070995)
1.6 9.8 GO:0015732 prostaglandin transport(GO:0015732)
1.6 6.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
1.6 6.5 GO:0051608 histamine transport(GO:0051608)
1.6 44.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.6 1.6 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
1.6 4.9 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.6 4.9 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
1.6 9.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
1.6 4.8 GO:0043605 cellular amide catabolic process(GO:0043605)
1.6 11.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.6 1.6 GO:0071288 cellular response to mercury ion(GO:0071288)
1.6 9.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.6 12.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.6 3.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
1.6 9.4 GO:0042088