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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SOX30

Z-value: 0.75

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Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
SOX30
ENSG00000039600.6 SRY-box transcription factor 30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079428_157079452,
hg19_v2_chr5_-_157079372_157079395		0.186.9e-03Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_11081828 12.48 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr12_-_11036844 12.28 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr12_-_11548496 12.25 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr12_-_11508520 11.33 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr12_-_11463353 10.69 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
PRB4
proline-rich protein BstNI subfamily 4
chr12_-_11002063 9.87 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr12_-_11422630 7.13 ENST00000381842.3
ENST00000538488.1
PRB3
proline-rich protein BstNI subfamily 3
chr12_-_11422739 6.75 ENST00000279573.7
PRB3
proline-rich protein BstNI subfamily 3
chr1_+_244998602 5.28 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr6_-_134639180 4.91 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr5_+_140739537 4.79 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr5_+_140729649 4.59 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr5_+_140772381 4.28 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr1_-_201476274 4.01 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr5_+_66254698 4.00 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_126240442 3.32 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr10_+_35415978 2.61 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr10_+_35415719 2.60 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr14_+_101299520 2.57 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr7_+_100770328 2.45 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr4_-_176733897 2.44 ENST00000393658.2
GPM6A
glycoprotein M6A
chr6_-_49712123 2.37 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr5_-_141338627 2.37 ENST00000231484.3
PCDH12
protocadherin 12
chr18_+_7946941 2.36 ENST00000444013.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr10_+_70480963 2.35 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr11_+_125365110 2.13 ENST00000527818.1
AP000708.1
AP000708.1
chr10_+_35416090 2.07 ENST00000354759.3
CREM
cAMP responsive element modulator
chr1_-_243418621 1.97 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr10_+_35416223 1.81 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr7_-_82792215 1.73 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr5_-_160279207 1.67 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr11_-_75236867 1.63 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr22_-_43485381 1.60 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
TTLL1
tubulin tyrosine ligase-like family, member 1
chr1_+_93913713 1.57 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr6_+_22146851 1.44 ENST00000606197.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr8_+_105352050 1.39 ENST00000297581.2
DCSTAMP
dendrocyte expressed seven transmembrane protein
chr5_+_170288856 1.37 ENST00000523189.1
RANBP17
RAN binding protein 17
chr1_-_243418344 1.37 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr6_-_11779014 1.35 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr12_-_10251603 1.35 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chrY_+_15016013 1.35 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr10_+_35484793 1.34 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr1_-_167883327 1.31 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr12_-_10251576 1.30 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr2_-_157198860 1.29 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr9_+_103235365 1.28 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr3_-_8686479 1.19 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr4_+_144303093 1.18 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr6_+_12290586 1.03 ENST00000379375.5
EDN1
endothelin 1
chr11_-_102323740 0.98 ENST00000398136.2
TMEM123
transmembrane protein 123
chr3_+_181429704 0.98 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr4_-_87028478 0.97 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr14_-_90421028 0.94 ENST00000267544.9
ENST00000316738.7
ENST00000538485.2
ENST00000556609.1
EFCAB11
EF-hand calcium binding domain 11
chr12_-_10251539 0.93 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr6_-_11779174 0.91 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr1_-_167883353 0.91 ENST00000545172.1
ADCY10
adenylate cyclase 10 (soluble)
chr14_-_90420862 0.90 ENST00000556005.1
ENST00000555872.1
EFCAB11
EF-hand calcium binding domain 11
chr7_-_44229022 0.87 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr11_-_102323489 0.84 ENST00000361236.3
TMEM123
transmembrane protein 123
chr8_-_82024290 0.76 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr19_-_17375541 0.74 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr3_-_57583130 0.74 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr2_-_162931052 0.71 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr22_-_30970560 0.70 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr8_+_24151553 0.60 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr12_-_10282742 0.57 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr3_-_165555200 0.55 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr2_-_166060552 0.50 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr2_-_166060571 0.45 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr5_-_59481406 0.39 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_71457970 0.38 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr8_+_42195972 0.36 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
POLB
polymerase (DNA directed), beta
chr4_-_70725856 0.36 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr5_+_140593509 0.31 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr22_+_31488433 0.31 ENST00000455608.1
SMTN
smoothelin
chr4_+_71458012 0.28 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chr11_+_63137251 0.28 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr16_+_87636474 0.27 ENST00000284262.2
JPH3
junctophilin 3
chr5_+_135468516 0.27 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr5_-_146461027 0.23 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_+_46402744 0.23 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr7_-_107443652 0.19 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr3_-_167191814 0.18 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr11_-_89224638 0.15 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr8_+_24151620 0.14 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr8_-_141810634 0.12 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr2_-_37899323 0.11 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr16_+_4545853 0.09 ENST00000575129.1
ENST00000398595.3
ENST00000414777.1
HMOX2
heme oxygenase (decycling) 2
chr1_-_26324534 0.07 ENST00000374284.1
ENST00000441420.1
ENST00000374282.3
PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
chr7_-_142176790 0.06 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr4_+_113152978 0.06 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr1_-_200379180 0.05 ENST00000294740.3
ZNF281
zinc finger protein 281
chr1_-_200379129 0.02 ENST00000367353.1
ZNF281
zinc finger protein 281

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.7 4.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.4 1.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4 5.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.3 1.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.0 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 1.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 3.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 13.9 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 0.6 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.7 GO:0036343 psychomotor behavior(GO:0036343)
0.2 1.0 GO:0001714 endodermal cell fate specification(GO:0001714)
0.2 1.6 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 10.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 9.9 GO:0001895 retina homeostasis(GO:0001895)
0.1 2.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 1.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.9 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 1.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.4 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 1.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 16.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.7 GO:0045176 apical protein localization(GO:0045176)
0.1 0.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.7 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 4.0 GO:0070527 platelet aggregation(GO:0070527)
0.0 2.4 GO:0003407 neural retina development(GO:0003407)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 1.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 1.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.8 GO:0042476 odontogenesis(GO:0042476)
0.0 0.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 4.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 2.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.7 GO:0099738 cell cortex region(GO:0099738)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.2 GO:0045178 basal part of cell(GO:0045178)
0.0 3.3 GO:0005814 centriole(GO:0005814)
0.0 2.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 10.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 20.5 GO:0005615 extracellular space(GO:0005615)
0.0 16.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 5.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 42.1 GO:0005576 extracellular region(GO:0005576)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 1.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 1.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 1.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 4.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 1.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.9 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.7 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 2.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 5.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 2.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 16.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 4.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 23.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 10.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 5.9 PID FOXO PATHWAY FoxO family signaling
0.1 2.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 3.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 2.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules