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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for SP3

Z-value: 2.42

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Transcription factors associated with SP3

Gene Symbol Gene ID Gene Info
SP3
ENSG00000172845.9 Sp3 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SP3hg19_v2_chr2_-_174830430_1748305630.531.7e-17Click!

Activity profile of SP3 motif

Sorted Z-values of SP3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_90015105 88.99 ENST00000567999.1
ENST00000566079.1
ENST00000566820.1
ENST00000562578.1
ENST00000561741.1
ENST00000268676.7
ENST00000562986.1
ENST00000569453.1
ENST00000567884.1
ENST00000569061.1
ENST00000418391.2
ENST00000561959.1
ENST00000567874.1
ENST00000570182.1
ENST00000563795.1
DEF8
differentially expressed in FDCP 8 homolog (mouse)
chr6_-_4135693 83.40 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
ECI2
enoyl-CoA delta isomerase 2
chr6_-_4135825 74.11 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
ECI2
enoyl-CoA delta isomerase 2
chr19_-_55919087 73.71 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chrX_-_152989798 66.07 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr19_-_291365 65.09 ENST00000591572.1
ENST00000269812.3
ENST00000434325.2
PPAP2C
phosphatidic acid phosphatase type 2C
chr19_-_291133 63.76 ENST00000327790.3
PPAP2C
phosphatidic acid phosphatase type 2C
chr19_+_54694119 60.04 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34
TSEN34 tRNA splicing endonuclease subunit
chr7_+_26241325 58.17 ENST00000456948.1
ENST00000409747.1
CBX3
chromobox homolog 3
chr11_+_65686952 57.52 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr10_+_120863587 57.39 ENST00000535029.1
ENST00000361432.2
ENST00000544016.1
FAM45A
family with sequence similarity 45, member A
chr11_+_1968508 56.74 ENST00000397298.3
ENST00000381519.1
ENST00000397297.3
ENST00000381514.3
ENST00000397294.3
MRPL23
mitochondrial ribosomal protein L23
chr19_+_49497121 53.50 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr20_+_32581452 53.35 ENST00000375114.3
ENST00000448364.1
RALY
RALY heterogeneous nuclear ribonucleoprotein
chr7_+_26241310 53.23 ENST00000396386.2
CBX3
chromobox homolog 3
chr11_+_65687158 53.22 ENST00000532933.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr7_+_116139744 53.15 ENST00000343213.2
CAV2
caveolin 2
chr17_-_76183111 52.88 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1
thymidine kinase 1, soluble
chr1_-_8939265 52.16 ENST00000489867.1
ENO1
enolase 1, (alpha)
chr11_-_535515 51.98 ENST00000311189.7
ENST00000451590.1
ENST00000417302.1
HRAS
Harvey rat sarcoma viral oncogene homolog
chrX_+_118602363 51.64 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr2_-_10588630 51.02 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr11_-_2950642 50.95 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr20_+_62371206 50.77 ENST00000266077.2
SLC2A4RG
SLC2A4 regulator
chr17_-_79481666 50.37 ENST00000575659.1
ACTG1
actin, gamma 1
chr1_-_225840747 50.10 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr18_+_657578 49.81 ENST00000323274.10
TYMS
thymidylate synthetase
chr1_+_10459111 49.69 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chr8_+_38854418 49.27 ENST00000481513.1
ENST00000487273.2
ADAM9
ADAM metallopeptidase domain 9
chr16_-_87903079 48.69 ENST00000261622.4
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr19_+_6361754 48.63 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr20_-_60718430 48.44 ENST00000370873.4
ENST00000370858.3
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr12_-_109125285 48.13 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr18_+_11981427 48.11 ENST00000269159.3
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr9_-_113018746 47.56 ENST00000374515.5
TXN
thioredoxin
chr2_+_235860616 47.51 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr19_+_49496705 46.70 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr1_+_43824577 46.46 ENST00000310955.6
CDC20
cell division cycle 20
chrX_-_152989531 46.45 ENST00000458587.2
ENST00000416815.1
BCAP31
B-cell receptor-associated protein 31
chr18_+_12947981 46.23 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr1_-_212004090 46.09 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr20_-_52210368 46.08 ENST00000371471.2
ZNF217
zinc finger protein 217
chr17_-_4852332 45.87 ENST00000572383.1
PFN1
profilin 1
chr18_+_12308231 45.78 ENST00000590103.1
ENST00000591909.1
ENST00000586653.1
ENST00000592683.1
ENST00000590967.1
ENST00000591208.1
ENST00000591463.1
TUBB6
tubulin, beta 6 class V
chr1_-_1822495 45.40 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_+_166808692 44.81 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr8_+_145149930 44.49 ENST00000318911.4
CYC1
cytochrome c-1
chr16_-_81129951 44.40 ENST00000315467.3
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr20_+_35202909 44.39 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr20_+_32581525 44.19 ENST00000246194.3
ENST00000413297.1
RALY
RALY heterogeneous nuclear ribonucleoprotein
chr11_+_65686802 44.18 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr6_-_159065741 43.95 ENST00000367085.3
ENST00000367089.3
DYNLT1
dynein, light chain, Tctex-type 1
chr20_+_60878005 43.94 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr3_+_23847432 43.46 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr17_+_1733276 43.35 ENST00000254719.5
RPA1
replication protein A1, 70kDa
chr17_-_20946338 42.73 ENST00000261497.4
USP22
ubiquitin specific peptidase 22
chr19_-_1095330 42.62 ENST00000586746.1
POLR2E
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr1_+_43824669 42.39 ENST00000372462.1
CDC20
cell division cycle 20
chr18_+_12948000 42.34 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1L
SEH1-like (S. cerevisiae)
chr17_-_73149921 41.45 ENST00000481647.1
ENST00000470924.1
HN1
hematological and neurological expressed 1
chr2_-_10952832 41.35 ENST00000540494.1
PDIA6
protein disulfide isomerase family A, member 6
chr12_-_118498958 41.19 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr15_-_90777277 41.12 ENST00000328649.6
CIB1
calcium and integrin binding 1 (calmyrin)
chr1_-_8938736 41.01 ENST00000234590.4
ENO1
enolase 1, (alpha)
chr19_-_1568057 40.82 ENST00000402693.4
ENST00000388824.6
MEX3D
mex-3 RNA binding family member D
chr8_-_102217796 40.67 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
ZNF706
zinc finger protein 706
chr16_+_88923494 40.39 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
TRAPPC2L
trafficking protein particle complex 2-like
chr2_-_179315786 39.83 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr1_+_236558694 39.83 ENST00000359362.5
EDARADD
EDAR-associated death domain
chr4_+_174089904 39.54 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_-_6453426 39.38 ENST00000545482.1
ACOT7
acyl-CoA thioesterase 7
chrX_-_153775426 39.27 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr19_+_54695098 39.19 ENST00000396388.2
TSEN34
TSEN34 tRNA splicing endonuclease subunit
chr3_-_53290016 39.04 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
TKT
transketolase
chr3_-_185542817 38.93 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr3_+_100053625 38.90 ENST00000497785.1
NIT2
nitrilase family, member 2
chr1_+_173446405 38.66 ENST00000340385.5
PRDX6
peroxiredoxin 6
chr5_+_138089100 38.52 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr11_+_65686728 38.31 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr18_+_657733 38.15 ENST00000323250.5
ENST00000323224.7
TYMS
thymidylate synthetase
chr19_-_42806723 38.13 ENST00000262890.3
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chrX_-_151999269 38.07 ENST00000370277.3
CETN2
centrin, EF-hand protein, 2
chr1_-_113249948 37.93 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr15_+_57210961 37.88 ENST00000557843.1
TCF12
transcription factor 12
chr4_+_57301896 37.82 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr9_-_113018835 37.81 ENST00000374517.5
TXN
thioredoxin
chr2_+_122494676 37.70 ENST00000455432.1
TSN
translin
chr12_+_6309517 37.65 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr19_+_49496782 37.51 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr2_-_179315490 37.51 ENST00000487082.1
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chrX_-_153707246 37.50 ENST00000407062.1
LAGE3
L antigen family, member 3
chr10_-_17659234 37.50 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_+_53342625 37.30 ENST00000388837.2
ENST00000550600.1
ENST00000388835.3
KRT18
keratin 18
chr14_+_105886150 37.03 ENST00000331320.7
ENST00000406191.1
MTA1
metastasis associated 1
chr3_+_49711777 36.99 ENST00000442186.1
ENST00000438011.1
ENST00000457042.1
APEH
acylaminoacyl-peptide hydrolase
chr16_+_29817841 36.91 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr15_+_52311398 36.81 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr19_+_36631867 36.80 ENST00000588780.1
CAPNS1
calpain, small subunit 1
chr14_-_69446034 36.79 ENST00000193403.6
ACTN1
actinin, alpha 1
chr14_-_105487381 36.78 ENST00000392590.3
ENST00000336219.3
CDCA4
cell division cycle associated 4
chr8_-_102217515 36.77 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
ZNF706
zinc finger protein 706
chr17_-_4852243 36.75 ENST00000225655.5
PFN1
profilin 1
chr15_-_72523454 36.63 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
PKM
pyruvate kinase, muscle
chr20_-_5107180 36.59 ENST00000379160.3
PCNA
proliferating cell nuclear antigen
chr5_-_133340682 36.50 ENST00000265333.3
VDAC1
voltage-dependent anion channel 1
chr22_+_43547937 36.46 ENST00000329563.4
TSPO
translocator protein (18kDa)
chr19_-_33166045 36.42 ENST00000586693.3
ENST00000587352.1
ENST00000586463.1
ENST00000306065.4
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr22_-_19166343 36.42 ENST00000215882.5
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_-_882966 36.17 ENST00000336868.3
NXN
nucleoredoxin
chr7_+_32996997 36.15 ENST00000242209.4
ENST00000538336.1
ENST00000538443.1
FKBP9
FK506 binding protein 9, 63 kDa
chrX_+_133594168 36.11 ENST00000298556.7
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr17_-_62658186 36.05 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr12_+_3068544 36.01 ENST00000540314.1
ENST00000536826.1
ENST00000359864.2
TEAD4
TEA domain family member 4
chr17_-_80606304 35.97 ENST00000392325.4
WDR45B
WD repeat domain 45B
chr9_+_91926103 35.87 ENST00000314355.6
CKS2
CDC28 protein kinase regulatory subunit 2
chr18_+_29077990 35.84 ENST00000261590.8
DSG2
desmoglein 2
chr7_-_97501432 35.82 ENST00000394309.3
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr8_+_26149007 35.73 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_+_64808675 35.73 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr19_-_42806444 35.71 ENST00000594989.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr7_-_97501411 35.44 ENST00000437628.1
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr22_-_18257178 35.41 ENST00000342111.5
BID
BH3 interacting domain death agonist
chr5_-_68665469 35.37 ENST00000217893.5
TAF9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
chr1_-_94703118 35.22 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr7_+_56119323 35.13 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
CCT6A
chaperonin containing TCP1, subunit 6A (zeta 1)
chr10_+_3109695 34.98 ENST00000381125.4
PFKP
phosphofructokinase, platelet
chr10_-_3214965 34.84 ENST00000451104.2
ENST00000224949.4
ENST00000380989.2
PITRM1
pitrilysin metallopeptidase 1
chr20_+_56884752 34.73 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr8_+_145582231 34.73 ENST00000526338.1
ENST00000402965.1
ENST00000534725.1
ENST00000532887.1
ENST00000329994.2
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr21_-_45196326 34.71 ENST00000291568.5
CSTB
cystatin B (stefin B)
chr22_-_50746027 34.70 ENST00000425954.1
ENST00000449103.1
PLXNB2
plexin B2
chr6_+_24775153 34.68 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr7_+_73868220 34.68 ENST00000455841.2
GTF2IRD1
GTF2I repeat domain containing 1
chrX_+_118370288 34.53 ENST00000535419.1
PGRMC1
progesterone receptor membrane component 1
chr9_+_131451480 34.52 ENST00000322030.8
SET
SET nuclear oncogene
chr2_+_238600933 34.52 ENST00000420665.1
ENST00000392000.4
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr15_-_91537723 34.46 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1
protein regulator of cytokinesis 1
chr1_+_26606608 34.41 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr8_+_61429728 34.40 ENST00000529579.1
RAB2A
RAB2A, member RAS oncogene family
chr1_+_54411995 34.37 ENST00000319223.4
ENST00000444987.1
LRRC42
leucine rich repeat containing 42
chr7_+_73868120 34.36 ENST00000265755.3
GTF2IRD1
GTF2I repeat domain containing 1
chr3_-_185542761 34.36 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr21_-_46237883 34.36 ENST00000397893.3
SUMO3
small ubiquitin-like modifier 3
chr1_+_41445413 34.26 ENST00000541520.1
CTPS1
CTP synthase 1
chr22_-_24322660 34.23 ENST00000404092.1
DDT
D-dopachrome tautomerase
chr11_+_832944 34.22 ENST00000322008.4
ENST00000397421.1
ENST00000529810.1
ENST00000526693.1
ENST00000525333.1
ENST00000524748.1
ENST00000527341.1
CD151
CD151 molecule (Raph blood group)
chr1_-_225615599 34.18 ENST00000421383.1
ENST00000272163.4
LBR
lamin B receptor
chr19_-_2015699 34.17 ENST00000255608.4
BTBD2
BTB (POZ) domain containing 2
chr7_+_148395733 34.02 ENST00000602748.1
CUL1
cullin 1
chr2_-_10952922 33.93 ENST00000272227.3
PDIA6
protein disulfide isomerase family A, member 6
chr13_+_28194873 33.86 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr20_-_33872548 33.72 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr5_+_68462837 33.69 ENST00000256442.5
CCNB1
cyclin B1
chr4_-_174256276 33.61 ENST00000296503.5
HMGB2
high mobility group box 2
chr1_-_150947343 33.57 ENST00000271688.6
ENST00000368954.5
CERS2
ceramide synthase 2
chr11_+_64808368 33.47 ENST00000531072.1
ENST00000398846.1
SAC3D1
SAC3 domain containing 1
chr16_-_81129845 33.46 ENST00000569885.1
ENST00000566566.1
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr2_-_64881018 33.37 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr2_+_10262857 33.36 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr2_-_174828892 33.30 ENST00000418194.2
SP3
Sp3 transcription factor
chr7_+_98972298 33.24 ENST00000252725.5
ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr10_-_17659357 33.19 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr19_+_35645817 33.13 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_12917364 33.11 ENST00000221486.4
RNASEH2A
ribonuclease H2, subunit A
chr20_+_17550691 33.07 ENST00000474024.1
DSTN
destrin (actin depolymerizing factor)
chr19_-_48894762 33.03 ENST00000600980.1
ENST00000330720.2
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_68299130 32.99 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr6_+_3000057 32.92 ENST00000397717.2
NQO2
NAD(P)H dehydrogenase, quinone 2
chr16_-_84651673 32.90 ENST00000262428.4
COTL1
coactosin-like 1 (Dictyostelium)
chr15_+_66161802 32.88 ENST00000566233.1
ENST00000565075.1
ENST00000435304.2
RAB11A
RAB11A, member RAS oncogene family
chr4_-_100871506 32.82 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr9_+_131452239 32.77 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr19_+_48824711 32.71 ENST00000599704.1
EMP3
epithelial membrane protein 3
chr12_-_58146128 32.66 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr3_+_171758344 32.65 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr7_+_16685756 32.58 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
BZW2
basic leucine zipper and W2 domains 2
chr20_-_33872518 32.46 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr6_+_138725343 32.46 ENST00000607197.1
ENST00000367697.3
HEBP2
heme binding protein 2
chr19_+_16187816 32.39 ENST00000588410.1
TPM4
tropomyosin 4
chr5_+_172385732 32.36 ENST00000519974.1
ENST00000521476.1
RPL26L1
ribosomal protein L26-like 1
chr1_-_152009460 32.16 ENST00000271638.2
S100A11
S100 calcium binding protein A11
chr2_+_172778952 32.12 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr3_+_49711391 32.11 ENST00000296456.5
ENST00000449966.1
APEH
acylaminoacyl-peptide hydrolase
chr1_+_955448 32.04 ENST00000379370.2
AGRN
agrin
chr2_-_215674374 32.02 ENST00000449967.2
ENST00000421162.1
ENST00000260947.4
BARD1
BRCA1 associated RING domain 1
chr16_+_89989687 32.01 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
TUBB3
Tubulin beta-3 chain
chr7_+_116166331 32.00 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr17_-_73150599 31.91 ENST00000392566.2
ENST00000581874.1
HN1
hematological and neurological expressed 1
chr20_+_43514320 31.86 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr17_-_4269768 31.85 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr16_-_84651647 31.74 ENST00000564057.1
COTL1
coactosin-like 1 (Dictyostelium)
chr1_-_24126892 31.71 ENST00000374497.3
ENST00000425913.1
GALE
UDP-galactose-4-epimerase
chr11_+_64009072 31.68 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr1_+_182992545 31.65 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr8_+_145582217 31.61 ENST00000530047.1
ENST00000527078.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr11_-_102323489 31.60 ENST00000361236.3
TMEM123
transmembrane protein 123
chr20_+_388679 31.56 ENST00000356286.5
ENST00000475269.1
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr1_+_94883931 31.52 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr1_+_65613340 31.49 ENST00000546702.1
AK4
adenylate kinase 4
chr20_+_17550489 31.44 ENST00000246069.7
DSTN
destrin (actin depolymerizing factor)

Network of associatons between targets according to the STRING database.

First level regulatory network of SP3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
38.3 153.2 GO:0019322 pentose biosynthetic process(GO:0019322)
34.5 137.9 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
33.7 101.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
31.5 126.0 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
28.3 85.0 GO:0046680 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
26.8 80.5 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
25.8 103.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
25.7 102.9 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
23.9 71.8 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
22.7 68.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
22.7 113.5 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
22.4 22.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
22.1 44.2 GO:0097212 lysosomal membrane organization(GO:0097212)
21.8 21.8 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
21.8 87.3 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
21.2 63.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
21.1 21.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
20.7 62.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
20.0 60.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
19.9 99.5 GO:0015862 uridine transport(GO:0015862)
19.7 78.6 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
19.6 58.7 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
19.5 58.4 GO:1902463 protein localization to cell leading edge(GO:1902463)
19.4 77.6 GO:0032218 riboflavin transport(GO:0032218)
19.3 77.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
19.1 95.5 GO:0035900 response to isolation stress(GO:0035900)
19.1 38.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
19.1 114.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
18.4 73.7 GO:0010796 regulation of multivesicular body size(GO:0010796)
18.4 55.2 GO:0007113 endomitotic cell cycle(GO:0007113)
17.7 124.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
17.7 88.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
17.5 52.6 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
17.5 52.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
17.3 103.8 GO:0006021 inositol biosynthetic process(GO:0006021)
17.2 86.2 GO:0042256 mature ribosome assembly(GO:0042256)
17.2 120.1 GO:0006226 dUMP biosynthetic process(GO:0006226)
17.2 103.0 GO:0015853 adenine transport(GO:0015853)
16.7 50.0 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
16.6 49.9 GO:0044209 AMP salvage(GO:0044209)
16.6 66.4 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
16.5 16.5 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
16.3 65.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
16.2 81.0 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
16.2 16.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
15.7 78.4 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
15.6 46.9 GO:0006597 spermine biosynthetic process(GO:0006597)
15.5 108.8 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
15.4 46.3 GO:0046098 guanine metabolic process(GO:0046098)
15.4 46.3 GO:1901873 regulation of post-translational protein modification(GO:1901873)
15.4 15.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
15.3 152.9 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
15.3 61.0 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
15.2 45.7 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
15.2 60.9 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
15.1 151.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
15.0 60.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
15.0 134.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
14.9 44.8 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
14.9 44.7 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
14.9 44.7 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
14.8 29.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
14.8 44.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
14.7 44.1 GO:0006059 hexitol metabolic process(GO:0006059)
14.6 87.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
14.6 102.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
14.5 72.6 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
14.5 58.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
14.4 57.6 GO:0006528 asparagine metabolic process(GO:0006528)
14.3 42.9 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
14.3 14.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
14.2 70.8 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
14.1 42.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
14.1 70.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
14.1 14.1 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814)
14.0 42.0 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
14.0 55.9 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
13.8 69.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
13.6 40.7 GO:0006097 glyoxylate cycle(GO:0006097)
13.5 40.4 GO:0061198 fungiform papilla formation(GO:0061198)
13.4 80.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
13.4 66.9 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
13.4 53.4 GO:0043335 protein unfolding(GO:0043335)
13.3 66.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
13.2 131.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
13.1 130.6 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
13.0 52.0 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
12.9 38.6 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
12.9 38.6 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
12.8 38.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
12.6 37.9 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
12.6 138.3 GO:0030043 actin filament fragmentation(GO:0030043)
12.6 12.6 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
12.6 37.7 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
12.5 99.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
12.4 24.7 GO:0006167 AMP biosynthetic process(GO:0006167)
12.2 48.9 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
12.1 60.5 GO:2000254 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
12.1 84.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
12.0 36.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
11.8 189.4 GO:0043248 proteasome assembly(GO:0043248)
11.8 47.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
11.8 35.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
11.8 58.8 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
11.7 46.9 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
11.7 11.7 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
11.7 11.7 GO:0046102 inosine metabolic process(GO:0046102)
11.6 220.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
11.5 11.5 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
11.5 11.5 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
11.5 11.5 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
11.5 149.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
11.5 80.4 GO:0000710 meiotic mismatch repair(GO:0000710)
11.5 11.5 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
11.4 45.8 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
11.4 91.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
11.3 45.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
11.3 34.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
11.3 67.9 GO:0006177 GMP biosynthetic process(GO:0006177)
11.3 101.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
11.2 56.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
11.2 33.7 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
11.2 33.5 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
11.1 22.1 GO:0005997 xylulose metabolic process(GO:0005997)
11.0 55.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
11.0 76.8 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
11.0 43.9 GO:0021564 vagus nerve development(GO:0021564)
10.9 152.7 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
10.9 65.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
10.8 10.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
10.6 10.6 GO:0006041 glucosamine metabolic process(GO:0006041)
10.6 138.3 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
10.6 53.1 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
10.6 31.7 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
10.6 95.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
10.6 21.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
10.5 105.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
10.4 52.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
10.4 62.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
10.4 62.2 GO:0030421 defecation(GO:0030421)
10.3 31.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
10.3 41.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
10.2 30.7 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
10.2 40.9 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
10.2 71.2 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
10.2 30.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
10.1 60.8 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
10.1 40.4 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
10.1 30.2 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
10.1 50.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
10.0 30.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
10.0 30.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
10.0 79.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
9.9 49.7 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
9.9 69.5 GO:0007144 female meiosis I(GO:0007144)
9.8 29.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
9.8 98.0 GO:0015939 pantothenate metabolic process(GO:0015939)
9.8 58.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
9.7 9.7 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872)
9.7 58.3 GO:0022614 membrane to membrane docking(GO:0022614)
9.6 48.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
9.6 19.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
9.5 142.8 GO:0090168 Golgi reassembly(GO:0090168)
9.5 38.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
9.5 28.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
9.4 66.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
9.4 28.3 GO:0043542 endothelial cell migration(GO:0043542)
9.4 28.2 GO:0006106 fumarate metabolic process(GO:0006106)
9.3 28.0 GO:0018158 protein oxidation(GO:0018158)
9.3 65.4 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
9.3 74.5 GO:0006527 arginine catabolic process(GO:0006527)
9.3 130.3 GO:0045793 positive regulation of cell size(GO:0045793)
9.3 37.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
9.1 36.5 GO:0008298 intracellular mRNA localization(GO:0008298)
9.1 27.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
9.0 9.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
9.0 189.5 GO:0051764 actin crosslink formation(GO:0051764)
9.0 9.0 GO:0010225 response to UV-C(GO:0010225)
9.0 26.9 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
8.9 26.8 GO:0015920 lipopolysaccharide transport(GO:0015920)
8.9 89.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
8.9 17.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
8.9 62.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
8.8 44.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
8.8 8.8 GO:0097374 sensory neuron axon guidance(GO:0097374)
8.8 26.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
8.8 35.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
8.8 17.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
8.8 26.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
8.8 26.3 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
8.7 87.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
8.7 43.6 GO:0030047 actin modification(GO:0030047)
8.7 644.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
8.7 104.0 GO:0019388 galactose catabolic process(GO:0019388)
8.7 69.3 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
8.6 25.9 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
8.6 25.8 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
8.6 8.6 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
8.6 17.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
8.6 17.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
8.6 25.7 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
8.5 68.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
8.5 8.5 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
8.5 34.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
8.5 25.6 GO:0006550 isoleucine catabolic process(GO:0006550)
8.5 34.0 GO:1902462 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
8.5 34.0 GO:0003164 His-Purkinje system development(GO:0003164)
8.5 25.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
8.4 33.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
8.4 8.4 GO:0015846 polyamine transport(GO:0015846)
8.3 58.4 GO:0042262 DNA protection(GO:0042262)
8.3 116.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
8.3 33.2 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
8.3 24.9 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
8.3 16.6 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
8.3 16.6 GO:0015866 ADP transport(GO:0015866)
8.3 49.5 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
8.2 8.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
8.2 32.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
8.1 32.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
8.1 129.7 GO:0000338 protein deneddylation(GO:0000338)
8.1 24.3 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
8.1 97.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
8.1 48.6 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
8.1 24.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
8.0 40.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
8.0 16.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305)
8.0 31.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
7.9 31.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
7.9 47.6 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
7.9 23.7 GO:0015680 intracellular copper ion transport(GO:0015680)
7.8 47.0 GO:0061441 renal artery morphogenesis(GO:0061441)
7.8 23.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
7.8 23.4 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
7.8 23.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
7.8 46.7 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
7.8 23.3 GO:1902570 protein localization to nucleolus(GO:1902570)
7.8 643.8 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
7.7 340.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
7.7 30.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
7.7 15.4 GO:0043555 regulation of translation in response to stress(GO:0043555)
7.7 38.5 GO:0002084 protein depalmitoylation(GO:0002084)
7.7 15.4 GO:0002188 translation reinitiation(GO:0002188)
7.7 23.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
7.7 23.0 GO:0001928 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
7.7 53.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
7.7 23.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
7.7 15.3 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
7.6 53.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
7.6 22.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
7.6 22.8 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
7.6 22.7 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
7.5 30.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
7.5 30.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
7.5 59.9 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
7.5 22.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
7.4 51.8 GO:0071896 protein localization to adherens junction(GO:0071896)
7.4 73.9 GO:0060056 mammary gland involution(GO:0060056)
7.4 155.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
7.4 22.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
7.3 22.0 GO:0006404 RNA import into nucleus(GO:0006404)
7.3 14.6 GO:0042816 vitamin B6 metabolic process(GO:0042816)
7.3 21.8 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
7.3 7.3 GO:0048254 snoRNA localization(GO:0048254)
7.3 7.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
7.2 43.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
7.2 7.2 GO:0006513 protein monoubiquitination(GO:0006513)
7.1 7.1 GO:0032506 cytokinetic process(GO:0032506)
7.1 35.7 GO:0032790 ribosome disassembly(GO:0032790)
7.1 7.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
7.1 14.2 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
7.1 28.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
7.1 7.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
7.0 42.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
7.0 168.7 GO:0032986 protein-DNA complex disassembly(GO:0032986)
7.0 49.1 GO:0070269 pyroptosis(GO:0070269)
7.0 21.0 GO:0035092 sperm chromatin condensation(GO:0035092)
7.0 42.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
7.0 215.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
6.9 13.8 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
6.9 6.9 GO:0060613 fat pad development(GO:0060613)
6.9 48.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
6.8 6.8 GO:0032808 lacrimal gland development(GO:0032808)
6.8 47.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
6.8 6.8 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
6.8 6.8 GO:0021511 spinal cord patterning(GO:0021511)
6.8 27.0 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
6.7 54.0 GO:0051096 positive regulation of helicase activity(GO:0051096)
6.7 67.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
6.7 33.6 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
6.7 40.3 GO:0007296 vitellogenesis(GO:0007296)
6.7 6.7 GO:0071035 nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
6.7 73.7 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
6.7 66.9 GO:0032075 positive regulation of nuclease activity(GO:0032075)
6.7 106.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
6.7 73.5 GO:1901070 GTP biosynthetic process(GO:0006183) guanosine-containing compound biosynthetic process(GO:1901070)
6.6 13.3 GO:0051167 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
6.6 53.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
6.6 13.3 GO:1903911 positive regulation of receptor clustering(GO:1903911)
6.6 456.9 GO:0045454 cell redox homeostasis(GO:0045454)
6.6 79.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
6.6 32.9 GO:0016129 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
6.6 65.6 GO:0010265 SCF complex assembly(GO:0010265)
6.5 19.6 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
6.5 13.0 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
6.5 117.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
6.5 297.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
6.5 58.1 GO:0009414 response to water deprivation(GO:0009414)
6.5 32.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
6.4 19.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
6.4 6.4 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
6.4 32.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
6.4 25.6 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
6.4 89.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
6.4 19.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
6.4 38.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
6.3 6.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
6.3 12.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
6.3 25.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
6.3 6.3 GO:2000395 ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
6.3 31.5 GO:1903333 negative regulation of protein folding(GO:1903333)
6.3 206.3 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
6.2 24.9 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
6.2 24.9 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
6.2 18.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
6.2 6.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
6.2 24.7 GO:0044375 regulation of peroxisome size(GO:0044375)
6.2 30.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
6.2 18.5 GO:0071344 diphosphate metabolic process(GO:0071344)
6.1 30.7 GO:0048478 replication fork protection(GO:0048478)
6.1 42.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
6.1 36.7 GO:0010643 cell communication by chemical coupling(GO:0010643)
6.1 12.2 GO:1901656 glycoside transport(GO:1901656)
6.1 177.0 GO:0031581 hemidesmosome assembly(GO:0031581)
6.1 6.1 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
6.1 67.1 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
6.1 18.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
6.0 72.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
6.0 24.2 GO:0072683 T cell extravasation(GO:0072683)
6.0 18.1 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
6.0 30.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
6.0 12.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
6.0 48.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
6.0 6.0 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
6.0 48.0 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
6.0 23.9 GO:0045218 zonula adherens maintenance(GO:0045218)
5.9 17.8 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
5.9 11.9 GO:0006740 NADPH regeneration(GO:0006740)
5.9 17.6 GO:0033341 regulation of collagen binding(GO:0033341)
5.9 17.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
5.9 46.9 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
5.9 17.6 GO:0003064 regulation of heart rate by hormone(GO:0003064)
5.8 11.7 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
5.8 17.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
5.8 126.8 GO:0071294 cellular response to zinc ion(GO:0071294)
5.7 23.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
5.7 149.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
5.7 51.6 GO:0006415 translational termination(GO:0006415)
5.7 5.7 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
5.7 34.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
5.7 17.0 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
5.7 22.7 GO:0031291 Ran protein signal transduction(GO:0031291)
5.7 45.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
5.7 34.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
5.7 28.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
5.6 39.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
5.6 16.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
5.6 50.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
5.6 28.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
5.6 22.4 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
5.6 11.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
5.5 5.5 GO:0060623 regulation of chromosome condensation(GO:0060623)
5.5 16.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
5.5 33.1 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
5.5 11.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
5.5 5.5 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
5.5 16.4 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
5.4 5.4 GO:0045210 FasL biosynthetic process(GO:0045210)
5.4 86.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
5.4 21.6 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
5.4 21.5 GO:0035879 plasma membrane lactate transport(GO:0035879)
5.4 16.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
5.4 26.9 GO:1905214 regulation of RNA binding(GO:1905214)
5.4 26.9 GO:0070836 caveola assembly(GO:0070836)
5.4 80.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
5.3 21.4 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
5.3 42.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
5.3 16.0 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
5.3 26.6 GO:0075525 viral translational termination-reinitiation(GO:0075525)
5.3 21.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
5.3 15.9 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
5.3 5.3 GO:0034214 protein hexamerization(GO:0034214)
5.3 47.4 GO:0060717 chorion development(GO:0060717)
5.3 189.3 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
5.2 26.0 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
5.2 26.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
5.2 15.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
5.1 5.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
5.1 36.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
5.1 41.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
5.1 15.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
5.1 20.5 GO:0060694 regulation of cholesterol transporter activity(GO:0060694)
5.1 10.2 GO:0003278