Project
averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for SPI1
Z-value: 3.78
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Transcription factors associated with SPI1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SPI1
|
ENSG00000066336.7 | Spi-1 proto-oncogene |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SPI1 | hg19_v2_chr11_-_47400078_47400127, hg19_v2_chr11_-_47399942_47399961 | 0.59 | 1.3e-21 | Click! |
Activity profile of SPI1 motif
Sorted Z-values of SPI1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_198608146 | 141.46 |
ENST00000367376.2
ENST00000352140.3 ENST00000594404.1 ENST00000598951.1 ENST00000530727.1 ENST00000442510.2 ENST00000367367.4 ENST00000348564.6 ENST00000367364.1 ENST00000413409.2 |
PTPRC
|
protein tyrosine phosphatase, receptor type, C |
| chr13_-_46756351 | 99.44 |
ENST00000323076.2
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin) |
| chr3_-_121379739 | 86.66 |
ENST00000428394.2
ENST00000314583.3 |
HCLS1
|
hematopoietic cell-specific Lyn substrate 1 |
| chr12_-_15114603 | 79.79 |
ENST00000228945.4
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr12_-_15114492 | 73.40 |
ENST00000541546.1
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chr6_-_32811771 | 64.75 |
ENST00000395339.3
ENST00000374882.3 |
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8 |
| chr6_-_32160622 | 60.33 |
ENST00000487761.1
ENST00000375040.3 |
GPSM3
|
G-protein signaling modulator 3 |
| chr1_-_167487808 | 58.48 |
ENST00000392122.3
|
CD247
|
CD247 molecule |
| chr2_+_69001913 | 57.98 |
ENST00000409030.3
ENST00000409220.1 |
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr1_-_167487758 | 57.94 |
ENST00000362089.5
|
CD247
|
CD247 molecule |
| chr12_+_54891495 | 57.08 |
ENST00000293373.6
|
NCKAP1L
|
NCK-associated protein 1-like |
| chr1_-_183560011 | 56.31 |
ENST00000367536.1
|
NCF2
|
neutrophil cytosolic factor 2 |
| chr11_-_58343319 | 55.98 |
ENST00000395074.2
|
LPXN
|
leupaxin |
| chr2_+_233925064 | 55.62 |
ENST00000359570.5
ENST00000538935.1 |
INPP5D
|
inositol polyphosphate-5-phosphatase, 145kDa |
| chr5_-_169725231 | 55.37 |
ENST00000046794.5
|
LCP2
|
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| chr11_-_3862206 | 54.92 |
ENST00000351018.4
|
RHOG
|
ras homolog family member G |
| chr6_+_31553901 | 53.38 |
ENST00000418507.2
ENST00000438075.2 ENST00000376100.3 ENST00000376111.4 |
LST1
|
leukocyte specific transcript 1 |
| chr5_+_169064245 | 53.06 |
ENST00000256935.8
|
DOCK2
|
dedicator of cytokinesis 2 |
| chr7_-_5569588 | 52.67 |
ENST00000417101.1
|
ACTB
|
actin, beta |
| chr19_+_49838653 | 51.63 |
ENST00000598095.1
ENST00000426897.2 ENST00000323906.4 ENST00000535669.2 ENST00000597602.1 ENST00000595660.1 |
CD37
|
CD37 molecule |
| chr6_+_32811885 | 51.40 |
ENST00000458296.1
ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1 |
TAPSAR1
PSMB9
|
TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9 |
| chr17_-_62084241 | 50.05 |
ENST00000449662.2
|
ICAM2
|
intercellular adhesion molecule 2 |
| chr1_-_150738261 | 49.57 |
ENST00000448301.2
ENST00000368985.3 |
CTSS
|
cathepsin S |
| chr11_+_128563652 | 49.48 |
ENST00000527786.2
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr12_+_7055767 | 49.38 |
ENST00000447931.2
|
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr12_-_118797475 | 49.24 |
ENST00000541786.1
ENST00000419821.2 ENST00000541878.1 |
TAOK3
|
TAO kinase 3 |
| chr6_-_31704282 | 49.24 |
ENST00000375784.3
ENST00000375779.2 |
CLIC1
|
chloride intracellular channel 1 |
| chr17_+_4618734 | 49.01 |
ENST00000571206.1
|
ARRB2
|
arrestin, beta 2 |
| chr12_+_7055631 | 48.85 |
ENST00000543115.1
ENST00000399448.1 |
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr8_+_56792355 | 48.60 |
ENST00000519728.1
|
LYN
|
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
| chr19_-_10450328 | 48.50 |
ENST00000160262.5
|
ICAM3
|
intercellular adhesion molecule 3 |
| chr19_-_10450287 | 47.83 |
ENST00000589261.1
ENST00000590569.1 ENST00000589580.1 ENST00000589249.1 |
ICAM3
|
intercellular adhesion molecule 3 |
| chr6_+_31553978 | 47.52 |
ENST00000376096.1
ENST00000376099.1 ENST00000376110.3 |
LST1
|
leukocyte specific transcript 1 |
| chr1_-_207095324 | 47.39 |
ENST00000530505.1
ENST00000367091.3 ENST00000442471.2 |
FAIM3
|
Fas apoptotic inhibitory molecule 3 |
| chr2_+_85804614 | 47.09 |
ENST00000263864.5
ENST00000409760.1 |
VAMP8
|
vesicle-associated membrane protein 8 |
| chr19_-_8642289 | 46.89 |
ENST00000596675.1
ENST00000338257.8 |
MYO1F
|
myosin IF |
| chr1_+_111415757 | 46.83 |
ENST00000429072.2
ENST00000271324.5 |
CD53
|
CD53 molecule |
| chr2_-_175499294 | 46.54 |
ENST00000392547.2
|
WIPF1
|
WAS/WASL interacting protein family, member 1 |
| chr1_-_183559693 | 46.23 |
ENST00000367535.3
ENST00000413720.1 ENST00000418089.1 |
NCF2
|
neutrophil cytosolic factor 2 |
| chr1_-_25256368 | 44.01 |
ENST00000308873.6
|
RUNX3
|
runt-related transcription factor 3 |
| chr22_-_37640277 | 43.68 |
ENST00000401529.3
ENST00000249071.6 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr6_-_42016385 | 43.26 |
ENST00000502771.1
ENST00000508143.1 ENST00000514588.1 ENST00000510503.1 ENST00000415497.2 ENST00000372988.4 |
CCND3
|
cyclin D3 |
| chr12_-_92539614 | 43.16 |
ENST00000256015.3
|
BTG1
|
B-cell translocation gene 1, anti-proliferative |
| chr16_-_88717423 | 42.81 |
ENST00000568278.1
ENST00000569359.1 ENST00000567174.1 |
CYBA
|
cytochrome b-245, alpha polypeptide |
| chr14_-_35344093 | 42.63 |
ENST00000382422.2
|
BAZ1A
|
bromodomain adjacent to zinc finger domain, 1A |
| chr22_+_37678424 | 42.41 |
ENST00000248901.6
|
CYTH4
|
cytohesin 4 |
| chr19_-_36399149 | 42.13 |
ENST00000585901.2
ENST00000544690.2 ENST00000424586.3 ENST00000262629.4 ENST00000589517.1 |
TYROBP
|
TYRO protein tyrosine kinase binding protein |
| chr15_+_75074410 | 40.99 |
ENST00000439220.2
|
CSK
|
c-src tyrosine kinase |
| chr8_+_56792377 | 40.37 |
ENST00000520220.2
|
LYN
|
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog |
| chr2_+_143886877 | 39.57 |
ENST00000295095.6
|
ARHGAP15
|
Rho GTPase activating protein 15 |
| chr17_+_43299241 | 38.91 |
ENST00000328118.3
|
FMNL1
|
formin-like 1 |
| chrX_+_128913906 | 38.58 |
ENST00000356892.3
|
SASH3
|
SAM and SH3 domain containing 3 |
| chr19_+_1077393 | 38.37 |
ENST00000590577.1
|
HMHA1
|
histocompatibility (minor) HA-1 |
| chr16_-_88717482 | 38.02 |
ENST00000261623.3
|
CYBA
|
cytochrome b-245, alpha polypeptide |
| chr14_-_23451467 | 37.53 |
ENST00000555074.1
ENST00000361265.4 |
RP11-298I3.5
AJUBA
|
RP11-298I3.5 ajuba LIM protein |
| chr14_-_23285011 | 36.97 |
ENST00000397532.3
|
SLC7A7
|
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| chr21_-_46340770 | 36.36 |
ENST00000397854.3
|
ITGB2
|
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| chr14_-_23285069 | 35.99 |
ENST00000554758.1
ENST00000397528.4 |
SLC7A7
|
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| chr12_+_25205666 | 35.82 |
ENST00000547044.1
|
LRMP
|
lymphoid-restricted membrane protein |
| chr12_+_25205568 | 35.44 |
ENST00000548766.1
ENST00000556887.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr2_+_68961934 | 34.32 |
ENST00000409202.3
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr2_+_68961905 | 34.08 |
ENST00000295381.3
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr11_+_60223225 | 33.77 |
ENST00000524807.1
ENST00000345732.4 |
MS4A1
|
membrane-spanning 4-domains, subfamily A, member 1 |
| chr11_-_72432950 | 33.41 |
ENST00000426523.1
ENST00000429686.1 |
ARAP1
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| chr1_-_31230650 | 32.96 |
ENST00000294507.3
|
LAPTM5
|
lysosomal protein transmembrane 5 |
| chr22_-_37640456 | 32.63 |
ENST00000405484.1
ENST00000441619.1 ENST00000406508.1 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr2_-_235405168 | 32.46 |
ENST00000339728.3
|
ARL4C
|
ADP-ribosylation factor-like 4C |
| chr15_+_75074385 | 32.39 |
ENST00000220003.9
|
CSK
|
c-src tyrosine kinase |
| chr11_+_60223312 | 32.38 |
ENST00000532491.1
ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1 |
MS4A1
|
membrane-spanning 4-domains, subfamily A, member 1 |
| chr17_-_29641104 | 32.25 |
ENST00000577894.1
ENST00000330927.4 |
EVI2B
|
ecotropic viral integration site 2B |
| chr9_-_137809718 | 31.81 |
ENST00000371806.3
|
FCN1
|
ficolin (collagen/fibrinogen domain containing) 1 |
| chr2_+_109204909 | 31.73 |
ENST00000393310.1
|
LIMS1
|
LIM and senescent cell antigen-like domains 1 |
| chr3_+_151986709 | 31.19 |
ENST00000495875.2
ENST00000493459.1 ENST00000324210.5 ENST00000459747.1 |
MBNL1
|
muscleblind-like splicing regulator 1 |
| chr11_-_47399942 | 30.95 |
ENST00000227163.4
|
SPI1
|
spleen focus forming virus (SFFV) proviral integration oncogene |
| chr5_-_131826457 | 30.91 |
ENST00000437654.1
ENST00000245414.4 |
IRF1
|
interferon regulatory factor 1 |
| chr8_+_22438009 | 30.87 |
ENST00000409417.1
|
PDLIM2
|
PDZ and LIM domain 2 (mystique) |
| chr17_+_43299156 | 30.80 |
ENST00000331495.3
|
FMNL1
|
formin-like 1 |
| chr2_-_64371546 | 30.77 |
ENST00000358912.4
|
PELI1
|
pellino E3 ubiquitin protein ligase 1 |
| chr15_-_80263506 | 30.65 |
ENST00000335661.6
|
BCL2A1
|
BCL2-related protein A1 |
| chr1_+_145439306 | 30.50 |
ENST00000425134.1
|
TXNIP
|
thioredoxin interacting protein |
| chr3_-_16555150 | 30.14 |
ENST00000334133.4
|
RFTN1
|
raftlin, lipid raft linker 1 |
| chr1_+_9711781 | 30.07 |
ENST00000536656.1
ENST00000377346.4 |
PIK3CD
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| chr11_+_65407331 | 29.91 |
ENST00000527525.1
|
SIPA1
|
signal-induced proliferation-associated 1 |
| chr7_+_98972298 | 29.80 |
ENST00000252725.5
|
ARPC1B
|
actin related protein 2/3 complex, subunit 1B, 41kDa |
| chr16_+_30484021 | 29.62 |
ENST00000358164.5
|
ITGAL
|
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| chr12_+_25205446 | 29.31 |
ENST00000557489.1
ENST00000354454.3 ENST00000536173.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr2_-_85637459 | 29.05 |
ENST00000409921.1
|
CAPG
|
capping protein (actin filament), gelsolin-like |
| chr7_-_115670804 | 28.99 |
ENST00000320239.7
|
TFEC
|
transcription factor EC |
| chr6_+_31554826 | 28.97 |
ENST00000376089.2
ENST00000396112.2 |
LST1
|
leukocyte specific transcript 1 |
| chrX_-_47489244 | 28.86 |
ENST00000469388.1
ENST00000396992.3 ENST00000377005.2 |
CFP
|
complement factor properdin |
| chr19_-_47220335 | 28.53 |
ENST00000601806.1
ENST00000593363.1 ENST00000598633.1 ENST00000595515.1 ENST00000433867.1 |
PRKD2
|
protein kinase D2 |
| chr9_+_77703414 | 28.50 |
ENST00000346234.6
|
OSTF1
|
osteoclast stimulating factor 1 |
| chr15_+_77287426 | 28.10 |
ENST00000558012.1
ENST00000267939.5 ENST00000379595.3 |
PSTPIP1
|
proline-serine-threonine phosphatase interacting protein 1 |
| chr7_-_115670792 | 28.02 |
ENST00000265440.7
ENST00000393485.1 |
TFEC
|
transcription factor EC |
| chr3_-_185641681 | 27.85 |
ENST00000259043.7
|
TRA2B
|
transformer 2 beta homolog (Drosophila) |
| chr1_+_32716840 | 27.51 |
ENST00000336890.5
|
LCK
|
lymphocyte-specific protein tyrosine kinase |
| chr2_-_96811170 | 27.50 |
ENST00000288943.4
|
DUSP2
|
dual specificity phosphatase 2 |
| chr12_-_51718436 | 27.41 |
ENST00000544402.1
|
BIN2
|
bridging integrator 2 |
| chr12_+_53848549 | 27.28 |
ENST00000439930.3
ENST00000548933.1 ENST00000562264.1 |
PCBP2
|
poly(rC) binding protein 2 |
| chr1_-_207095212 | 26.89 |
ENST00000420007.2
|
FAIM3
|
Fas apoptotic inhibitory molecule 3 |
| chr22_+_37257015 | 26.64 |
ENST00000447071.1
ENST00000248899.6 ENST00000397147.4 |
NCF4
|
neutrophil cytosolic factor 4, 40kDa |
| chr16_-_21663919 | 26.37 |
ENST00000569602.1
|
IGSF6
|
immunoglobulin superfamily, member 6 |
| chr4_+_103423055 | 26.33 |
ENST00000505458.1
|
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| chr1_+_32739733 | 26.24 |
ENST00000333070.4
|
LCK
|
lymphocyte-specific protein tyrosine kinase |
| chr7_+_74188309 | 26.04 |
ENST00000289473.4
ENST00000433458.1 |
NCF1
|
neutrophil cytosolic factor 1 |
| chr16_+_30483962 | 26.04 |
ENST00000356798.6
|
ITGAL
|
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| chr11_-_47400078 | 25.86 |
ENST00000378538.3
|
SPI1
|
spleen focus forming virus (SFFV) proviral integration oncogene |
| chr6_+_31582961 | 25.85 |
ENST00000376059.3
ENST00000337917.7 |
AIF1
|
allograft inflammatory factor 1 |
| chr8_+_22437965 | 25.69 |
ENST00000409141.1
ENST00000265810.4 |
PDLIM2
|
PDZ and LIM domain 2 (mystique) |
| chr1_-_159894319 | 25.61 |
ENST00000320307.4
|
TAGLN2
|
transgelin 2 |
| chr17_+_7461781 | 25.36 |
ENST00000349228.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr15_-_40600026 | 25.26 |
ENST00000456256.2
ENST00000557821.1 |
PLCB2
|
phospholipase C, beta 2 |
| chr4_-_40631859 | 25.23 |
ENST00000295971.7
ENST00000319592.4 |
RBM47
|
RNA binding motif protein 47 |
| chr1_-_111743285 | 25.13 |
ENST00000357640.4
|
DENND2D
|
DENN/MADD domain containing 2D |
| chr14_-_24616426 | 24.84 |
ENST00000216802.5
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr11_+_65408273 | 24.81 |
ENST00000394227.3
|
SIPA1
|
signal-induced proliferation-associated 1 |
| chr15_+_81589254 | 24.81 |
ENST00000394652.2
|
IL16
|
interleukin 16 |
| chr1_-_159893507 | 24.70 |
ENST00000368096.1
|
TAGLN2
|
transgelin 2 |
| chr4_-_174255536 | 24.49 |
ENST00000446922.2
|
HMGB2
|
high mobility group box 2 |
| chr17_+_7461580 | 24.44 |
ENST00000483039.1
ENST00000396542.1 |
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr16_-_89043377 | 24.34 |
ENST00000436887.2
ENST00000448839.1 ENST00000360302.2 |
CBFA2T3
|
core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| chr8_-_134072593 | 24.30 |
ENST00000427060.2
|
SLA
|
Src-like-adaptor |
| chr17_+_72462525 | 24.11 |
ENST00000360141.3
|
CD300A
|
CD300a molecule |
| chr17_-_20370847 | 24.10 |
ENST00000423676.3
ENST00000324290.5 |
LGALS9B
|
lectin, galactoside-binding, soluble, 9B |
| chr11_+_128563948 | 23.67 |
ENST00000534087.2
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr2_+_161993412 | 23.60 |
ENST00000259075.2
ENST00000432002.1 |
TANK
|
TRAF family member-associated NFKB activator |
| chr17_+_7461613 | 23.52 |
ENST00000438470.1
ENST00000436057.1 |
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr19_+_41768401 | 23.25 |
ENST00000352456.3
ENST00000595018.1 ENST00000597725.1 |
HNRNPUL1
|
heterogeneous nuclear ribonucleoprotein U-like 1 |
| chr19_+_42381173 | 23.11 |
ENST00000221972.3
|
CD79A
|
CD79a molecule, immunoglobulin-associated alpha |
| chr14_+_102276209 | 22.96 |
ENST00000445439.3
ENST00000334743.5 ENST00000557095.1 |
PPP2R5C
|
protein phosphatase 2, regulatory subunit B', gamma |
| chr1_+_32716857 | 22.80 |
ENST00000482949.1
ENST00000495610.2 |
LCK
|
lymphocyte-specific protein tyrosine kinase |
| chr2_+_65454926 | 22.77 |
ENST00000542850.1
ENST00000377982.4 |
ACTR2
|
ARP2 actin-related protein 2 homolog (yeast) |
| chr2_+_65454863 | 22.77 |
ENST00000260641.5
|
ACTR2
|
ARP2 actin-related protein 2 homolog (yeast) |
| chrX_-_70331298 | 22.60 |
ENST00000456850.2
ENST00000473378.1 ENST00000487883.1 ENST00000374202.2 |
IL2RG
|
interleukin 2 receptor, gamma |
| chr17_+_7461849 | 22.58 |
ENST00000338784.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr11_-_67120974 | 22.45 |
ENST00000539074.1
ENST00000312419.3 |
POLD4
|
polymerase (DNA-directed), delta 4, accessory subunit |
| chr8_-_102216925 | 22.33 |
ENST00000517844.1
|
ZNF706
|
zinc finger protein 706 |
| chr6_+_89790490 | 22.26 |
ENST00000336032.3
|
PNRC1
|
proline-rich nuclear receptor coactivator 1 |
| chr3_-_18480260 | 22.03 |
ENST00000454909.2
|
SATB1
|
SATB homeobox 1 |
| chr12_-_53601055 | 21.96 |
ENST00000552972.1
ENST00000422257.3 ENST00000267082.5 |
ITGB7
|
integrin, beta 7 |
| chr6_+_89790459 | 21.89 |
ENST00000369472.1
|
PNRC1
|
proline-rich nuclear receptor coactivator 1 |
| chr4_-_103746683 | 21.86 |
ENST00000504211.1
ENST00000508476.1 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr4_-_103747011 | 21.82 |
ENST00000350435.7
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr16_-_89043605 | 21.75 |
ENST00000268679.4
|
CBFA2T3
|
core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| chr19_+_6772710 | 21.70 |
ENST00000304076.2
ENST00000602142.1 ENST00000596764.1 |
VAV1
|
vav 1 guanine nucleotide exchange factor |
| chrX_-_107018969 | 21.59 |
ENST00000372383.4
|
TSC22D3
|
TSC22 domain family, member 3 |
| chr12_-_53601000 | 21.46 |
ENST00000338737.4
ENST00000549086.2 |
ITGB7
|
integrin, beta 7 |
| chr1_+_153330322 | 21.38 |
ENST00000368738.3
|
S100A9
|
S100 calcium binding protein A9 |
| chr11_-_72433346 | 21.35 |
ENST00000334211.8
|
ARAP1
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| chrX_-_154688276 | 21.27 |
ENST00000369445.2
|
F8A3
|
coagulation factor VIII-associated 3 |
| chrX_+_154114635 | 21.03 |
ENST00000369446.2
|
F8A1
|
coagulation factor VIII-associated 1 |
| chr10_-_72362515 | 21.01 |
ENST00000373209.2
ENST00000441259.1 |
PRF1
|
perforin 1 (pore forming protein) |
| chr2_-_153573887 | 21.01 |
ENST00000493468.2
ENST00000545856.1 |
PRPF40A
|
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) |
| chrX_+_48542168 | 20.94 |
ENST00000376701.4
|
WAS
|
Wiskott-Aldrich syndrome |
| chr11_-_47400062 | 20.90 |
ENST00000533030.1
|
SPI1
|
spleen focus forming virus (SFFV) proviral integration oncogene |
| chr11_-_102323740 | 20.83 |
ENST00000398136.2
|
TMEM123
|
transmembrane protein 123 |
| chr8_+_74903580 | 20.83 |
ENST00000284818.2
ENST00000518893.1 |
LY96
|
lymphocyte antigen 96 |
| chr21_-_15918618 | 20.55 |
ENST00000400564.1
ENST00000400566.1 |
SAMSN1
|
SAM domain, SH3 domain and nuclear localization signals 1 |
| chr7_-_76829125 | 20.54 |
ENST00000248598.5
|
FGL2
|
fibrinogen-like 2 |
| chr11_+_75110530 | 20.53 |
ENST00000531188.1
ENST00000530164.1 ENST00000422465.2 ENST00000278572.6 ENST00000534440.1 ENST00000527446.1 ENST00000526608.1 ENST00000527273.1 ENST00000524851.1 |
RPS3
|
ribosomal protein S3 |
| chr2_+_109204743 | 20.52 |
ENST00000332345.6
|
LIMS1
|
LIM and senescent cell antigen-like domains 1 |
| chr2_-_153574480 | 20.51 |
ENST00000410080.1
|
PRPF40A
|
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) |
| chr4_+_103422471 | 20.44 |
ENST00000226574.4
ENST00000394820.4 |
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| chr4_-_185395672 | 20.40 |
ENST00000393593.3
|
IRF2
|
interferon regulatory factor 2 |
| chr10_-_27149851 | 20.39 |
ENST00000376142.2
ENST00000359188.4 ENST00000376139.2 ENST00000376160.1 |
ABI1
|
abl-interactor 1 |
| chr2_+_182321925 | 20.35 |
ENST00000339307.4
ENST00000397033.2 |
ITGA4
|
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| chr1_-_184943610 | 20.15 |
ENST00000367511.3
|
FAM129A
|
family with sequence similarity 129, member A |
| chr16_-_21663950 | 19.97 |
ENST00000268389.4
|
IGSF6
|
immunoglobulin superfamily, member 6 |
| chr16_-_28506840 | 19.97 |
ENST00000569430.1
|
CLN3
|
ceroid-lipofuscinosis, neuronal 3 |
| chr12_-_110888103 | 19.97 |
ENST00000426440.1
ENST00000228825.7 |
ARPC3
|
actin related protein 2/3 complex, subunit 3, 21kDa |
| chr19_+_42387228 | 19.72 |
ENST00000354532.3
ENST00000599846.1 ENST00000347545.4 |
ARHGEF1
|
Rho guanine nucleotide exchange factor (GEF) 1 |
| chr16_+_30205225 | 19.69 |
ENST00000345535.4
ENST00000251303.6 |
SLX1A
|
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) |
| chr10_-_43892668 | 19.68 |
ENST00000544000.1
|
HNRNPF
|
heterogeneous nuclear ribonucleoprotein F |
| chr17_+_72462766 | 19.50 |
ENST00000392625.3
ENST00000361933.3 ENST00000310828.5 |
CD300A
|
CD300a molecule |
| chr16_+_67063142 | 19.49 |
ENST00000412916.2
|
CBFB
|
core-binding factor, beta subunit |
| chr10_-_27149904 | 19.42 |
ENST00000376166.1
ENST00000376138.3 ENST00000355394.4 ENST00000346832.5 ENST00000376134.3 ENST00000376137.4 ENST00000536334.1 ENST00000490841.2 |
ABI1
|
abl-interactor 1 |
| chr8_-_102217515 | 19.41 |
ENST00000520347.1
ENST00000523922.1 ENST00000520984.1 |
ZNF706
|
zinc finger protein 706 |
| chr7_+_99971129 | 19.29 |
ENST00000394000.2
ENST00000350573.2 |
PILRA
|
paired immunoglobin-like type 2 receptor alpha |
| chr16_+_29465822 | 19.23 |
ENST00000330181.5
ENST00000351581.4 |
SLX1B
|
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) |
| chrX_+_11777671 | 19.22 |
ENST00000380693.3
ENST00000380692.2 |
MSL3
|
male-specific lethal 3 homolog (Drosophila) |
| chr5_+_35856951 | 19.19 |
ENST00000303115.3
ENST00000343305.4 ENST00000506850.1 ENST00000511982.1 |
IL7R
|
interleukin 7 receptor |
| chr14_+_23340822 | 19.16 |
ENST00000359591.4
|
LRP10
|
low density lipoprotein receptor-related protein 10 |
| chr16_+_67063036 | 19.12 |
ENST00000290858.6
ENST00000564034.1 |
CBFB
|
core-binding factor, beta subunit |
| chr16_+_28505955 | 19.12 |
ENST00000564831.1
ENST00000328423.5 ENST00000431282.1 |
APOBR
|
apolipoprotein B receptor |
| chr17_-_34417479 | 19.00 |
ENST00000225245.5
|
CCL3
|
chemokine (C-C motif) ligand 3 |
| chr3_-_105588231 | 18.88 |
ENST00000545639.1
ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1 |
CBLB
|
Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| chr4_-_103746924 | 18.61 |
ENST00000505207.1
ENST00000502404.1 ENST00000507845.1 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr7_+_99971068 | 18.52 |
ENST00000198536.2
ENST00000453419.1 |
PILRA
|
paired immunoglobin-like type 2 receptor alpha |
| chr10_-_27149792 | 18.07 |
ENST00000376140.3
ENST00000376170.4 |
ABI1
|
abl-interactor 1 |
| chr10_-_98031310 | 18.02 |
ENST00000427367.2
ENST00000413476.2 |
BLNK
|
B-cell linker |
| chr19_+_48248779 | 17.99 |
ENST00000246802.5
|
GLTSCR2
|
glioma tumor suppressor candidate region gene 2 |
| chr9_-_88969303 | 17.94 |
ENST00000277141.6
ENST00000375963.3 |
ZCCHC6
|
zinc finger, CCHC domain containing 6 |
| chrX_+_118602363 | 17.79 |
ENST00000317881.8
|
SLC25A5
|
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 |
| chr8_-_101965559 | 17.79 |
ENST00000353245.3
|
YWHAZ
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
| chr7_+_50344289 | 17.66 |
ENST00000413698.1
ENST00000359197.5 ENST00000331340.3 ENST00000357364.4 ENST00000343574.5 ENST00000349824.4 ENST00000346667.4 ENST00000440768.2 |
IKZF1
|
IKAROS family zinc finger 1 (Ikaros) |
| chr11_+_1874200 | 17.64 |
ENST00000311604.3
|
LSP1
|
lymphocyte-specific protein 1 |
| chr5_-_142783694 | 17.58 |
ENST00000394466.2
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| chr2_+_202125219 | 17.51 |
ENST00000323492.7
|
CASP8
|
caspase 8, apoptosis-related cysteine peptidase |
| chr12_-_120638902 | 17.49 |
ENST00000551150.1
ENST00000313104.5 ENST00000547191.1 ENST00000546989.1 ENST00000392514.4 ENST00000228306.4 ENST00000550856.1 |
RPLP0
|
ribosomal protein, large, P0 |
| chr17_-_38721711 | 17.46 |
ENST00000578085.1
ENST00000246657.2 |
CCR7
|
chemokine (C-C motif) receptor 7 |
Network of associatons between targets according to the STRING database.
First level regulatory network of SPI1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 38.3 | 153.2 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 29.7 | 89.0 | GO:0070668 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668) |
| 28.3 | 141.5 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539) |
| 24.7 | 197.8 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 20.4 | 101.9 | GO:1904845 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 19.4 | 77.7 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 18.5 | 55.6 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 15.9 | 63.8 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 15.7 | 47.1 | GO:1903595 | positive regulation of histamine secretion by mast cell(GO:1903595) |
| 15.2 | 45.5 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 14.7 | 73.4 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 14.3 | 57.1 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358) |
| 13.7 | 54.8 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 12.2 | 73.0 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 12.0 | 12.0 | GO:1904124 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 11.7 | 47.0 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 10.9 | 54.7 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 10.7 | 32.2 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 10.4 | 124.3 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 10.3 | 30.9 | GO:0034124 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) |
| 10.2 | 30.7 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 9.8 | 49.0 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 9.3 | 46.4 | GO:0010956 | negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) |
| 9.1 | 36.4 | GO:2000538 | regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 9.0 | 36.1 | GO:0003138 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 8.9 | 143.1 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 8.9 | 35.6 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 8.8 | 43.9 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 8.4 | 25.3 | GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) |
| 7.8 | 23.5 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 7.8 | 147.6 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 7.7 | 30.8 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 7.3 | 51.0 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
| 7.2 | 36.0 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 7.1 | 21.4 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 7.0 | 27.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 6.9 | 76.3 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 6.6 | 53.1 | GO:0044351 | macropinocytosis(GO:0044351) |
| 6.5 | 104.2 | GO:0045651 | positive regulation of macrophage differentiation(GO:0045651) |
| 6.1 | 127.9 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 5.8 | 46.1 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 5.7 | 34.3 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 5.6 | 16.7 | GO:0052250 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 5.5 | 22.2 | GO:0016068 | regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068) |
| 5.5 | 44.1 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 5.2 | 25.8 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
| 5.1 | 36.0 | GO:0002349 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 5.1 | 15.2 | GO:0002339 | B cell selection(GO:0002339) B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 4.9 | 34.5 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 4.9 | 4.9 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 4.9 | 24.4 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 4.8 | 33.6 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 4.6 | 18.5 | GO:0030242 | pexophagy(GO:0030242) |
| 4.5 | 9.1 | GO:0033029 | regulation of neutrophil apoptotic process(GO:0033029) |
| 4.4 | 13.3 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 4.4 | 21.8 | GO:0002669 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) |
| 4.4 | 13.1 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 4.3 | 30.1 | GO:0032594 | protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596) |
| 4.2 | 25.4 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 4.2 | 25.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 4.2 | 41.7 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 4.1 | 12.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 4.0 | 16.1 | GO:0016334 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
| 4.0 | 12.0 | GO:1903676 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 4.0 | 55.7 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 3.9 | 30.8 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 3.8 | 19.2 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 3.8 | 7.7 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
| 3.8 | 19.0 | GO:0043307 | eosinophil activation(GO:0043307) |
| 3.8 | 26.5 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 3.8 | 112.7 | GO:0045730 | respiratory burst(GO:0045730) |
| 3.8 | 116.4 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 3.7 | 18.4 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 3.7 | 22.0 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 3.7 | 69.7 | GO:0051014 | actin filament severing(GO:0051014) |
| 3.6 | 3.6 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 3.5 | 13.9 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 3.4 | 13.6 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 3.4 | 26.8 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 3.3 | 43.2 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 3.3 | 19.8 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 3.2 | 42.1 | GO:0002281 | macrophage activation involved in immune response(GO:0002281) |
| 3.1 | 24.5 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 3.0 | 15.2 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 3.0 | 12.0 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 3.0 | 17.8 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 2.9 | 20.5 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 2.9 | 11.5 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 2.9 | 28.9 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 2.8 | 56.2 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 2.8 | 8.4 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 2.7 | 40.8 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 2.7 | 8.2 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 2.7 | 38.1 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 2.7 | 48.2 | GO:0002347 | response to tumor cell(GO:0002347) |
| 2.7 | 5.3 | GO:0002384 | hepatic immune response(GO:0002384) |
| 2.6 | 10.3 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 2.5 | 10.2 | GO:2000567 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
| 2.5 | 5.0 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 2.5 | 10.0 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 2.5 | 22.6 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 2.4 | 7.3 | GO:1903772 | ubiquitin-dependent endocytosis(GO:0070086) regulation of viral budding via host ESCRT complex(GO:1903772) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 2.4 | 14.6 | GO:1903800 | regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 2.4 | 77.8 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 2.4 | 12.1 | GO:0002634 | regulation of germinal center formation(GO:0002634) |
| 2.4 | 9.6 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 2.4 | 9.6 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 2.4 | 62.1 | GO:0010447 | response to acidic pH(GO:0010447) |
| 2.3 | 58.3 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 2.3 | 18.0 | GO:0070424 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) |
| 2.2 | 55.4 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 2.2 | 37.1 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 2.1 | 20.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 2.0 | 6.1 | GO:2000017 | positive regulation of determination of dorsal identity(GO:2000017) |
| 2.0 | 5.9 | GO:0001928 | regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178) |
| 2.0 | 37.4 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 2.0 | 3.9 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 1.9 | 21.4 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 1.9 | 5.8 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 1.9 | 42.0 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 1.8 | 25.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 1.8 | 24.8 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 1.8 | 3.5 | GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947) |
| 1.7 | 10.5 | GO:0043316 | cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435) |
| 1.7 | 12.1 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 1.7 | 27.4 | GO:0097320 | membrane tubulation(GO:0097320) |
| 1.7 | 23.9 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 1.7 | 13.7 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 1.7 | 8.5 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) positive regulation of IRE1-mediated unfolded protein response(GO:1903896) |
| 1.7 | 1.7 | GO:0045360 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 1.7 | 5.1 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 1.7 | 210.8 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 1.7 | 18.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 1.7 | 36.4 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 1.6 | 13.1 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 1.6 | 94.5 | GO:0045576 | mast cell activation(GO:0045576) |
| 1.6 | 25.6 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 1.6 | 236.6 | GO:0002433 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 1.6 | 11.0 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 1.5 | 4.6 | GO:0060380 | regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744) |
| 1.5 | 4.5 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
| 1.5 | 7.4 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
| 1.5 | 59.5 | GO:1901224 | positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
| 1.4 | 19.9 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
| 1.4 | 5.6 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 1.4 | 13.8 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 1.4 | 6.9 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 1.4 | 100.1 | GO:0002220 | innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 1.4 | 31.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 1.4 | 12.3 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 1.4 | 4.1 | GO:0010957 | negative regulation of vitamin D biosynthetic process(GO:0010957) |
| 1.4 | 12.2 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 1.3 | 34.8 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 1.3 | 9.0 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
| 1.3 | 10.1 | GO:0006116 | NADH oxidation(GO:0006116) |
| 1.3 | 13.9 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 1.3 | 8.8 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 1.2 | 17.3 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 1.2 | 3.7 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 1.2 | 50.0 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 1.2 | 8.4 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 1.2 | 3.6 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 1.2 | 13.1 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 1.2 | 8.2 | GO:0071569 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 1.2 | 17.5 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 1.2 | 7.0 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 1.2 | 29.2 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 1.2 | 5.8 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 1.2 | 8.1 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 1.1 | 3.4 | GO:0018201 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 1.1 | 27.2 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 1.1 | 19.1 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
| 1.1 | 16.8 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
| 1.1 | 53.4 | GO:0042100 | B cell proliferation(GO:0042100) |
| 1.1 | 7.8 | GO:2001138 | regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140) |
| 1.1 | 3.3 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 1.1 | 7.6 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 1.1 | 6.5 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 1.1 | 88.6 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 1.1 | 4.3 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 1.1 | 153.5 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 1.1 | 14.9 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 1.0 | 12.1 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 1.0 | 5.0 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 1.0 | 17.7 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 1.0 | 10.8 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 1.0 | 12.5 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 1.0 | 5.7 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.9 | 12.9 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.9 | 28.5 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.9 | 26.7 | GO:0006266 | DNA ligation(GO:0006266) |
| 0.9 | 4.5 | GO:0019230 | proprioception(GO:0019230) |
| 0.9 | 11.5 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.9 | 6.1 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.9 | 58.5 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.9 | 2.6 | GO:0060613 | fat pad development(GO:0060613) |
| 0.8 | 5.0 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.8 | 11.5 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.8 | 12.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.8 | 29.5 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.8 | 14.6 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.8 | 12.0 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.8 | 1.5 | GO:0061056 | sclerotome development(GO:0061056) |
| 0.8 | 12.1 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.7 | 95.8 | GO:0007338 | single fertilization(GO:0007338) |
| 0.7 | 18.3 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.7 | 5.8 | GO:0002517 | T cell tolerance induction(GO:0002517) |
| 0.7 | 104.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.7 | 7.2 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.7 | 22.2 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.7 | 3.5 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.7 | 9.0 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.7 | 9.6 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.7 | 2.0 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.7 | 2.0 | GO:0033385 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 0.6 | 5.2 | GO:1903748 | negative regulation of establishment of protein localization to mitochondrion(GO:1903748) |
| 0.6 | 21.8 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.6 | 6.2 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.6 | 35.1 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.6 | 0.6 | GO:2000137 | cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) |
| 0.6 | 24.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.6 | 2.8 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.6 | 6.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.6 | 3.3 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.5 | 24.2 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.5 | 15.5 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.5 | 20.8 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.5 | 4.8 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.5 | 11.5 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.5 | 4.1 | GO:0001780 | neutrophil homeostasis(GO:0001780) |
| 0.5 | 15.1 | GO:0046039 | GTP metabolic process(GO:0046039) |
| 0.5 | 9.2 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.5 | 7.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.4 | 0.8 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.4 | 4.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.4 | 2.4 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.4 | 1.9 | GO:0050729 | positive regulation of inflammatory response(GO:0050729) |
| 0.4 | 1.5 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.4 | 17.6 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.4 | 5.5 | GO:0017145 | stem cell division(GO:0017145) |
| 0.4 | 78.3 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.4 | 7.2 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.4 | 1.1 | GO:0036079 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.4 | 2.8 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.3 | 3.5 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.3 | 39.5 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.3 | 11.0 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.3 | 2.5 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.3 | 6.4 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.3 | 5.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.3 | 43.2 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.3 | 5.5 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.3 | 1.8 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.3 | 2.6 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.3 | 0.3 | GO:0045416 | positive regulation of interleukin-8 biosynthetic process(GO:0045416) |
| 0.3 | 17.7 | GO:0030218 | erythrocyte differentiation(GO:0030218) |
| 0.3 | 20.4 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.3 | 9.3 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.3 | 8.5 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.3 | 0.5 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
| 0.3 | 20.2 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.2 | 4.2 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.2 | 4.0 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.2 | 4.6 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.2 | 9.3 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.2 | 4.4 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.2 | 17.7 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.2 | 1.4 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.2 | 8.4 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.2 | 0.8 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.2 | 8.2 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.2 | 4.7 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.2 | 6.1 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 0.2 | 4.1 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.2 | 2.3 | GO:0060117 | auditory receptor cell development(GO:0060117) |
| 0.2 | 7.1 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.2 | 2.1 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.2 | 11.8 | GO:0042113 | B cell activation(GO:0042113) |
| 0.2 | 0.9 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.2 | 1.9 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.2 | 3.5 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
| 0.2 | 2.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.2 | 0.5 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.2 | 1.5 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.2 | 23.0 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.2 | 1.9 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.2 | 9.2 | GO:0048678 | response to axon injury(GO:0048678) |
| 0.2 | 40.6 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.2 | 6.1 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 8.0 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 1.5 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.1 | 0.7 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.1 | 3.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 1.7 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.1 | 5.6 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
| 0.1 | 1.6 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 0.3 | GO:0032930 | positive regulation of superoxide anion generation(GO:0032930) |
| 0.1 | 2.1 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 1.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 3.5 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 0.6 | GO:0097480 | synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480) |
| 0.1 | 1.6 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 1.0 | GO:0042108 | positive regulation of cytokine biosynthetic process(GO:0042108) |
| 0.1 | 0.4 | GO:0032048 | cardiolipin metabolic process(GO:0032048) cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.1 | 0.7 | GO:0036507 | protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 0.2 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.1 | 1.6 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.1 | 0.9 | GO:0010659 | striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) |
| 0.1 | 0.8 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 1.0 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.0 | 0.4 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 0.3 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.0 | 0.6 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 10.4 | GO:0051260 | protein homooligomerization(GO:0051260) |
| 0.0 | 1.0 | GO:0031294 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.0 | 2.1 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.0 | 2.9 | GO:1990830 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.0 | 1.5 | GO:0048278 | vesicle docking(GO:0048278) |
| 0.0 | 0.6 | GO:0021983 | pituitary gland development(GO:0021983) |
| 0.0 | 0.4 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 0.2 | GO:0055078 | sodium ion homeostasis(GO:0055078) |
| 0.0 | 1.0 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 2.1 | GO:0001503 | ossification(GO:0001503) |
| 0.0 | 0.2 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.6 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 1.1 | GO:0008033 | tRNA processing(GO:0008033) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 21.5 | 236.5 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 19.4 | 155.2 | GO:0032010 | phagolysosome(GO:0032010) |
| 17.8 | 89.0 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 15.9 | 63.8 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 15.3 | 92.0 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
| 14.5 | 116.2 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 11.1 | 55.4 | GO:0036398 | TCR signalosome(GO:0036398) |
| 9.6 | 19.1 | GO:0042627 | chylomicron(GO:0042627) |
| 9.2 | 55.4 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 9.0 | 125.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 8.2 | 164.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 7.8 | 102.0 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 7.1 | 49.6 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 6.9 | 27.5 | GO:0097422 | tubular endosome(GO:0097422) |
| 6.8 | 20.5 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 6.4 | 31.8 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 6.1 | 6.1 | GO:1902911 | serine/threonine protein kinase complex(GO:1902554) protein kinase complex(GO:1902911) |
| 5.7 | 34.3 | GO:0071817 | MMXD complex(GO:0071817) |
| 5.6 | 22.4 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 5.4 | 26.8 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 5.3 | 37.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 5.0 | 95.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 5.0 | 50.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 5.0 | 34.8 | GO:0072487 | MSL complex(GO:0072487) |
| 4.2 | 12.5 | GO:0034271 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 4.1 | 69.7 | GO:0032059 | bleb(GO:0032059) |
| 4.1 | 52.7 | GO:0097433 | dense body(GO:0097433) |
| 4.0 | 216.8 | GO:0001772 | immunological synapse(GO:0001772) |
| 3.9 | 42.6 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 3.8 | 15.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 3.8 | 11.4 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 3.7 | 22.4 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 3.6 | 32.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 3.3 | 10.0 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 3.3 | 49.8 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 3.2 | 16.1 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 3.1 | 12.2 | GO:0005687 | U4 snRNP(GO:0005687) |
| 3.0 | 21.0 | GO:0044194 | cytolytic granule(GO:0044194) |
| 2.9 | 46.9 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 2.8 | 22.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 2.8 | 22.5 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 2.5 | 44.4 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 2.5 | 9.9 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 2.2 | 32.8 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 2.2 | 13.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 2.2 | 167.2 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 2.1 | 29.3 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 2.0 | 13.9 | GO:0030870 | Mre11 complex(GO:0030870) |
| 1.9 | 13.6 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 1.9 | 13.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 1.9 | 13.3 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 1.9 | 7.5 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 1.8 | 10.8 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 1.7 | 55.0 | GO:0005685 | U1 snRNP(GO:0005685) |
| 1.6 | 8.2 | GO:0000125 | PCAF complex(GO:0000125) |
| 1.6 | 14.6 | GO:0032039 | integrator complex(GO:0032039) |
| 1.6 | 4.8 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 1.6 | 1.6 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 1.6 | 11.0 | GO:0097452 | GAIT complex(GO:0097452) |
| 1.5 | 132.6 | GO:0035580 | specific granule lumen(GO:0035580) |
| 1.5 | 4.5 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 1.4 | 5.8 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 1.4 | 15.2 | GO:1990907 | beta-catenin-TCF complex(GO |