averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SPI1 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000066336.7	Spi-1 proto-oncogene

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SPI1	hg19_v2_chr11_-_47400078_47400127, hg19_v2_chr11_-_47399942_47399961	0.59	1.3e-21	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_198608146 Show fit	141.46	ENST00000367376.2 ENST00000352140.3 ENST00000594404.1 ENST00000598951.1 ENST00000530727.1 ENST00000442510.2 ENST00000367367.4 ENST00000348564.6 ENST00000367364.1 ENST00000413409.2	PTPRC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, receptor type, C
chr13_-_46756351 Show fit	99.44	ENST00000323076.2	LCP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_121379739 Show fit	86.66	ENST00000428394.2 ENST00000314583.3	HCLS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hematopoietic cell-specific Lyn substrate 1
chr12_-_15114603 Show fit	79.79	ENST00000228945.4	ARHGDIB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr12_-_15114492 Show fit	73.40	ENST00000541546.1	ARHGDIB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr6_-_32811771 Show fit	64.75	ENST00000395339.3 ENST00000374882.3	PSMB8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) subunit, beta type, 8
chr6_-_32160622 Show fit	60.33	ENST00000487761.1 ENST00000375040.3	GPSM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G-protein signaling modulator 3
chr1_-_167487808 Show fit	58.48	ENST00000392122.3	CD247 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD247 molecule
chr2_+_69001913 Show fit	57.98	ENST00000409030.3 ENST00000409220.1	ARHGAP25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 25
chr1_-_167487758 Show fit	57.94	ENST00000362089.5	CD247 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD247 molecule
chr12_+_54891495 Show fit	57.08	ENST00000293373.6	NCKAP1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NCK-associated protein 1-like
chr1_-_183560011 Show fit	56.31	ENST00000367536.1	NCF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neutrophil cytosolic factor 2
chr11_-_58343319 Show fit	55.98	ENST00000395074.2	LPXN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leupaxin
chr2_+_233925064 Show fit	55.62	ENST00000359570.5 ENST00000538935.1	INPP5D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inositol polyphosphate-5-phosphatase, 145kDa
chr5_-_169725231 Show fit	55.37	ENST00000046794.5	LCP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_3862206 Show fit	54.92	ENST00000351018.4	RHOG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member G
chr6_+_31553901 Show fit	53.38	ENST00000418507.2 ENST00000438075.2 ENST00000376100.3 ENST00000376111.4	LST1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leukocyte specific transcript 1
chr5_+_169064245 Show fit	53.06	ENST00000256935.8	DOCK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dedicator of cytokinesis 2
chr7_-_5569588 Show fit	52.67	ENST00000417101.1	ACTB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin, beta
chr19_+_49838653 Show fit	51.63	ENST00000598095.1 ENST00000426897.2 ENST00000323906.4 ENST00000535669.2 ENST00000597602.1 ENST00000595660.1	CD37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD37 molecule
chr6_+_32811885 Show fit	51.40	ENST00000458296.1 ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1	TAPSAR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit PSMB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9
chr17_-_62084241 Show fit	50.05	ENST00000449662.2	ICAM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intercellular adhesion molecule 2
chr1_-_150738261 Show fit	49.57	ENST00000448301.2 ENST00000368985.3	CTSS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cathepsin S
chr11_+_128563652 Show fit	49.48	ENST00000527786.2	FLI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr12_+_7055767 Show fit	49.38	ENST00000447931.2	PTPN6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr12_-_118797475 Show fit	49.24	ENST00000541786.1 ENST00000419821.2 ENST00000541878.1	TAOK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TAO kinase 3
chr6_-_31704282 Show fit	49.24	ENST00000375784.3 ENST00000375779.2	CLIC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride intracellular channel 1
chr17_+_4618734 Show fit	49.01	ENST00000571206.1	ARRB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	arrestin, beta 2
chr12_+_7055631 Show fit	48.85	ENST00000543115.1 ENST00000399448.1	PTPN6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr8_+_56792355 Show fit	48.60	ENST00000519728.1	LYN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr19_-_10450328 Show fit	48.50	ENST00000160262.5	ICAM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intercellular adhesion molecule 3
chr19_-_10450287 Show fit	47.83	ENST00000589261.1 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intercellular adhesion molecule 3
chr6_+_31553978 Show fit	47.52	ENST00000376096.1 ENST00000376099.1 ENST00000376110.3	LST1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leukocyte specific transcript 1
chr1_-_207095324 Show fit	47.39	ENST00000530505.1 ENST00000367091.3 ENST00000442471.2	FAIM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fas apoptotic inhibitory molecule 3
chr2_+_85804614 Show fit	47.09	ENST00000263864.5 ENST00000409760.1	VAMP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vesicle-associated membrane protein 8
chr19_-_8642289 Show fit	46.89	ENST00000596675.1 ENST00000338257.8	MYO1F Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin IF
chr1_+_111415757 Show fit	46.83	ENST00000429072.2 ENST00000271324.5	CD53 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD53 molecule
chr2_-_175499294 Show fit	46.54	ENST00000392547.2	WIPF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WAS/WASL interacting protein family, member 1
chr1_-_183559693 Show fit	46.23	ENST00000367535.3 ENST00000413720.1 ENST00000418089.1	NCF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neutrophil cytosolic factor 2
chr1_-_25256368 Show fit	44.01	ENST00000308873.6	RUNX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	runt-related transcription factor 3
chr22_-_37640277 Show fit	43.68	ENST00000401529.3 ENST00000249071.6	RAC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_-_42016385 Show fit	43.26	ENST00000502771.1 ENST00000508143.1 ENST00000514588.1 ENST00000510503.1 ENST00000415497.2 ENST00000372988.4	CCND3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin D3
chr12_-_92539614 Show fit	43.16	ENST00000256015.3	BTG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B-cell translocation gene 1, anti-proliferative
chr16_-_88717423 Show fit	42.81	ENST00000568278.1 ENST00000569359.1 ENST00000567174.1	CYBA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome b-245, alpha polypeptide
chr14_-_35344093 Show fit	42.63	ENST00000382422.2	BAZ1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	bromodomain adjacent to zinc finger domain, 1A
chr22_+_37678424 Show fit	42.41	ENST00000248901.6	CYTH4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytohesin 4
chr19_-_36399149 Show fit	42.13	ENST00000585901.2 ENST00000544690.2 ENST00000424586.3 ENST00000262629.4 ENST00000589517.1	TYROBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TYRO protein tyrosine kinase binding protein
chr15_+_75074410 Show fit	40.99	ENST00000439220.2	CSK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	c-src tyrosine kinase
chr8_+_56792377 Show fit	40.37	ENST00000520220.2	LYN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr2_+_143886877 Show fit	39.57	ENST00000295095.6	ARHGAP15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 15
chr17_+_43299241 Show fit	38.91	ENST00000328118.3	FMNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	formin-like 1
chrX_+_128913906 Show fit	38.58	ENST00000356892.3	SASH3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SAM and SH3 domain containing 3
chr19_+_1077393 Show fit	38.37	ENST00000590577.1	HMHA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histocompatibility (minor) HA-1
chr16_-_88717482 Show fit	38.02	ENST00000261623.3	CYBA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome b-245, alpha polypeptide
chr14_-_23451467 Show fit	37.53	ENST00000555074.1 ENST00000361265.4	RP11-298I3.5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit AJUBA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-298I3.5 ajuba LIM protein
chr14_-_23285011 Show fit	36.97	ENST00000397532.3	SLC7A7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr21_-_46340770 Show fit	36.36	ENST00000397854.3	ITGB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_23285069 Show fit	35.99	ENST00000554758.1 ENST00000397528.4	SLC7A7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_+_25205666 Show fit	35.82	ENST00000547044.1	LRMP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphoid-restricted membrane protein
chr12_+_25205568 Show fit	35.44	ENST00000548766.1 ENST00000556887.1	LRMP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphoid-restricted membrane protein
chr2_+_68961934 Show fit	34.32	ENST00000409202.3	ARHGAP25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 25
chr2_+_68961905 Show fit	34.08	ENST00000295381.3	ARHGAP25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 25
chr11_+_60223225 Show fit	33.77	ENST00000524807.1 ENST00000345732.4	MS4A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane-spanning 4-domains, subfamily A, member 1
chr11_-_72432950 Show fit	33.41	ENST00000426523.1 ENST00000429686.1	ARAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_-_31230650 Show fit	32.96	ENST00000294507.3	LAPTM5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysosomal protein transmembrane 5
chr22_-_37640456 Show fit	32.63	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_-_235405168 Show fit	32.46	ENST00000339728.3	ARL4C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 4C
chr15_+_75074385 Show fit	32.39	ENST00000220003.9	CSK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	c-src tyrosine kinase
chr11_+_60223312 Show fit	32.38	ENST00000532491.1 ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1	MS4A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane-spanning 4-domains, subfamily A, member 1
chr17_-_29641104 Show fit	32.25	ENST00000577894.1 ENST00000330927.4	EVI2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ecotropic viral integration site 2B
chr9_-_137809718 Show fit	31.81	ENST00000371806.3	FCN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ficolin (collagen/fibrinogen domain containing) 1
chr2_+_109204909 Show fit	31.73	ENST00000393310.1	LIMS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and senescent cell antigen-like domains 1
chr3_+_151986709 Show fit	31.19	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscleblind-like splicing regulator 1
chr11_-_47399942 Show fit	30.95	ENST00000227163.4	SPI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spleen focus forming virus (SFFV) proviral integration oncogene
chr5_-_131826457 Show fit	30.91	ENST00000437654.1 ENST00000245414.4	IRF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon regulatory factor 1
chr8_+_22438009 Show fit	30.87	ENST00000409417.1	PDLIM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PDZ and LIM domain 2 (mystique)
chr17_+_43299156 Show fit	30.80	ENST00000331495.3	FMNL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	formin-like 1
chr2_-_64371546 Show fit	30.77	ENST00000358912.4	PELI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pellino E3 ubiquitin protein ligase 1
chr15_-_80263506 Show fit	30.65	ENST00000335661.6	BCL2A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-related protein A1
chr1_+_145439306 Show fit	30.50	ENST00000425134.1	TXNIP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin interacting protein
chr3_-_16555150 Show fit	30.14	ENST00000334133.4	RFTN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	raftlin, lipid raft linker 1
chr1_+_9711781 Show fit	30.07	ENST00000536656.1 ENST00000377346.4	PIK3CD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr11_+_65407331 Show fit	29.91	ENST00000527525.1	SIPA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal-induced proliferation-associated 1
chr7_+_98972298 Show fit	29.80	ENST00000252725.5	ARPC1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 1B, 41kDa
chr16_+_30484021 Show fit	29.62	ENST00000358164.5	ITGAL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr12_+_25205446 Show fit	29.31	ENST00000557489.1 ENST00000354454.3 ENST00000536173.1	LRMP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphoid-restricted membrane protein
chr2_-_85637459 Show fit	29.05	ENST00000409921.1	CAPG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	capping protein (actin filament), gelsolin-like
chr7_-_115670804 Show fit	28.99	ENST00000320239.7	TFEC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor EC
chr6_+_31554826 Show fit	28.97	ENST00000376089.2 ENST00000396112.2	LST1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leukocyte specific transcript 1
chrX_-_47489244 Show fit	28.86	ENST00000469388.1 ENST00000396992.3 ENST00000377005.2	CFP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	complement factor properdin
chr19_-_47220335 Show fit	28.53	ENST00000601806.1 ENST00000593363.1 ENST00000598633.1 ENST00000595515.1 ENST00000433867.1	PRKD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase D2
chr9_+_77703414 Show fit	28.50	ENST00000346234.6	OSTF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	osteoclast stimulating factor 1
chr15_+_77287426 Show fit	28.10	ENST00000558012.1 ENST00000267939.5 ENST00000379595.3	PSTPIP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proline-serine-threonine phosphatase interacting protein 1
chr7_-_115670792 Show fit	28.02	ENST00000265440.7 ENST00000393485.1	TFEC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor EC
chr3_-_185641681 Show fit	27.85	ENST00000259043.7	TRA2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transformer 2 beta homolog (Drosophila)
chr1_+_32716840 Show fit	27.51	ENST00000336890.5	LCK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte-specific protein tyrosine kinase
chr2_-_96811170 Show fit	27.50	ENST00000288943.4	DUSP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 2
chr12_-_51718436 Show fit	27.41	ENST00000544402.1	BIN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	bridging integrator 2
chr12_+_53848549 Show fit	27.28	ENST00000439930.3 ENST00000548933.1 ENST00000562264.1	PCBP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	poly(rC) binding protein 2
chr1_-_207095212 Show fit	26.89	ENST00000420007.2	FAIM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fas apoptotic inhibitory molecule 3
chr22_+_37257015 Show fit	26.64	ENST00000447071.1 ENST00000248899.6 ENST00000397147.4	NCF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neutrophil cytosolic factor 4, 40kDa
chr16_-_21663919 Show fit	26.37	ENST00000569602.1	IGSF6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin superfamily, member 6
chr4_+_103423055 Show fit	26.33	ENST00000505458.1	NFKB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_32739733 Show fit	26.24	ENST00000333070.4	LCK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte-specific protein tyrosine kinase
chr7_+_74188309 Show fit	26.04	ENST00000289473.4 ENST00000433458.1	NCF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neutrophil cytosolic factor 1
chr16_+_30483962 Show fit	26.04	ENST00000356798.6	ITGAL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr11_-_47400078 Show fit	25.86	ENST00000378538.3	SPI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spleen focus forming virus (SFFV) proviral integration oncogene
chr6_+_31582961 Show fit	25.85	ENST00000376059.3 ENST00000337917.7	AIF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	allograft inflammatory factor 1
chr8_+_22437965 Show fit	25.69	ENST00000409141.1 ENST00000265810.4	PDLIM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PDZ and LIM domain 2 (mystique)
chr1_-_159894319 Show fit	25.61	ENST00000320307.4	TAGLN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin 2
chr17_+_7461781 Show fit	25.36	ENST00000349228.4	TNFSF13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr15_-_40600026 Show fit	25.26	ENST00000456256.2 ENST00000557821.1	PLCB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase C, beta 2
chr4_-_40631859 Show fit	25.23	ENST00000295971.7 ENST00000319592.4	RBM47 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein 47
chr1_-_111743285 Show fit	25.13	ENST00000357640.4	DENND2D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DENN/MADD domain containing 2D
chr14_-_24616426 Show fit	24.84	ENST00000216802.5	PSME2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_+_65408273 Show fit	24.81	ENST00000394227.3	SIPA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal-induced proliferation-associated 1
chr15_+_81589254 Show fit	24.81	ENST00000394652.2	IL16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 16
chr1_-_159893507 Show fit	24.70	ENST00000368096.1	TAGLN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin 2
chr4_-_174255536 Show fit	24.49	ENST00000446922.2	HMGB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	high mobility group box 2
chr17_+_7461580 Show fit	24.44	ENST00000483039.1 ENST00000396542.1	TNFSF13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr16_-_89043377 Show fit	24.34	ENST00000436887.2 ENST00000448839.1 ENST00000360302.2	CBFA2T3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr8_-_134072593 Show fit	24.30	ENST00000427060.2	SLA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Src-like-adaptor
chr17_+_72462525 Show fit	24.11	ENST00000360141.3	CD300A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD300a molecule
chr17_-_20370847 Show fit	24.10	ENST00000423676.3 ENST00000324290.5	LGALS9B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lectin, galactoside-binding, soluble, 9B
chr11_+_128563948 Show fit	23.67	ENST00000534087.2	FLI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr2_+_161993412 Show fit	23.60	ENST00000259075.2 ENST00000432002.1	TANK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TRAF family member-associated NFKB activator
chr17_+_7461613 Show fit	23.52	ENST00000438470.1 ENST00000436057.1	TNFSF13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr19_+_41768401 Show fit	23.25	ENST00000352456.3 ENST00000595018.1 ENST00000597725.1	HNRNPUL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein U-like 1
chr19_+_42381173 Show fit	23.11	ENST00000221972.3	CD79A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD79a molecule, immunoglobulin-associated alpha
chr14_+_102276209 Show fit	22.96	ENST00000445439.3 ENST00000334743.5 ENST00000557095.1	PPP2R5C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B', gamma
chr1_+_32716857 Show fit	22.80	ENST00000482949.1 ENST00000495610.2	LCK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte-specific protein tyrosine kinase
chr2_+_65454926 Show fit	22.77	ENST00000542850.1 ENST00000377982.4	ACTR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ARP2 actin-related protein 2 homolog (yeast)
chr2_+_65454863 Show fit	22.77	ENST00000260641.5	ACTR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ARP2 actin-related protein 2 homolog (yeast)
chrX_-_70331298 Show fit	22.60	ENST00000456850.2 ENST00000473378.1 ENST00000487883.1 ENST00000374202.2	IL2RG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 2 receptor, gamma
chr17_+_7461849 Show fit	22.58	ENST00000338784.4	TNFSF13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr11_-_67120974 Show fit	22.45	ENST00000539074.1 ENST00000312419.3	POLD4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (DNA-directed), delta 4, accessory subunit
chr8_-_102216925 Show fit	22.33	ENST00000517844.1	ZNF706 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 706
chr6_+_89790490 Show fit	22.26	ENST00000336032.3	PNRC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proline-rich nuclear receptor coactivator 1
chr3_-_18480260 Show fit	22.03	ENST00000454909.2	SATB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SATB homeobox 1
chr12_-_53601055 Show fit	21.96	ENST00000552972.1 ENST00000422257.3 ENST00000267082.5	ITGB7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, beta 7
chr6_+_89790459 Show fit	21.89	ENST00000369472.1	PNRC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proline-rich nuclear receptor coactivator 1
chr4_-_103746683 Show fit	21.86	ENST00000504211.1 ENST00000508476.1	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr4_-_103747011 Show fit	21.82	ENST00000350435.7	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr16_-_89043605 Show fit	21.75	ENST00000268679.4	CBFA2T3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr19_+_6772710 Show fit	21.70	ENST00000304076.2 ENST00000602142.1 ENST00000596764.1	VAV1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vav 1 guanine nucleotide exchange factor
chrX_-_107018969 Show fit	21.59	ENST00000372383.4	TSC22D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TSC22 domain family, member 3
chr12_-_53601000 Show fit	21.46	ENST00000338737.4 ENST00000549086.2	ITGB7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, beta 7
chr1_+_153330322 Show fit	21.38	ENST00000368738.3	S100A9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S100 calcium binding protein A9
chr11_-_72433346 Show fit	21.35	ENST00000334211.8	ARAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chrX_-_154688276 Show fit	21.27	ENST00000369445.2	F8A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coagulation factor VIII-associated 3
chrX_+_154114635 Show fit	21.03	ENST00000369446.2	F8A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coagulation factor VIII-associated 1
chr10_-_72362515 Show fit	21.01	ENST00000373209.2 ENST00000441259.1	PRF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	perforin 1 (pore forming protein)
chr2_-_153573887 Show fit	21.01	ENST00000493468.2 ENST00000545856.1	PRPF40A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chrX_+_48542168 Show fit	20.94	ENST00000376701.4	WAS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Wiskott-Aldrich syndrome
chr11_-_47400062 Show fit	20.90	ENST00000533030.1	SPI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spleen focus forming virus (SFFV) proviral integration oncogene
chr11_-_102323740 Show fit	20.83	ENST00000398136.2	TMEM123 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 123
chr8_+_74903580 Show fit	20.83	ENST00000284818.2 ENST00000518893.1	LY96 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte antigen 96
chr21_-_15918618 Show fit	20.55	ENST00000400564.1 ENST00000400566.1	SAMSN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr7_-_76829125 Show fit	20.54	ENST00000248598.5	FGL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrinogen-like 2
chr11_+_75110530 Show fit	20.53	ENST00000531188.1 ENST00000530164.1 ENST00000422465.2 ENST00000278572.6 ENST00000534440.1 ENST00000527446.1 ENST00000526608.1 ENST00000527273.1 ENST00000524851.1	RPS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S3
chr2_+_109204743 Show fit	20.52	ENST00000332345.6	LIMS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and senescent cell antigen-like domains 1
chr2_-_153574480 Show fit	20.51	ENST00000410080.1	PRPF40A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr4_+_103422471 Show fit	20.44	ENST00000226574.4 ENST00000394820.4	NFKB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_-_185395672 Show fit	20.40	ENST00000393593.3	IRF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon regulatory factor 2
chr10_-_27149851 Show fit	20.39	ENST00000376142.2 ENST00000359188.4 ENST00000376139.2 ENST00000376160.1	ABI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	abl-interactor 1
chr2_+_182321925 Show fit	20.35	ENST00000339307.4 ENST00000397033.2	ITGA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_-_184943610 Show fit	20.15	ENST00000367511.3	FAM129A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 129, member A
chr16_-_21663950 Show fit	19.97	ENST00000268389.4	IGSF6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin superfamily, member 6
chr16_-_28506840 Show fit	19.97	ENST00000569430.1	CLN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr12_-_110888103 Show fit	19.97	ENST00000426440.1 ENST00000228825.7	ARPC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin related protein 2/3 complex, subunit 3, 21kDa
chr19_+_42387228 Show fit	19.72	ENST00000354532.3 ENST00000599846.1 ENST00000347545.4	ARHGEF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho guanine nucleotide exchange factor (GEF) 1
chr16_+_30205225 Show fit	19.69	ENST00000345535.4 ENST00000251303.6	SLX1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr10_-_43892668 Show fit	19.68	ENST00000544000.1	HNRNPF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr17_+_72462766 Show fit	19.50	ENST00000392625.3 ENST00000361933.3 ENST00000310828.5	CD300A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD300a molecule
chr16_+_67063142 Show fit	19.49	ENST00000412916.2	CBFB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	core-binding factor, beta subunit
chr10_-_27149904 Show fit	19.42	ENST00000376166.1 ENST00000376138.3 ENST00000355394.4 ENST00000346832.5 ENST00000376134.3 ENST00000376137.4 ENST00000536334.1 ENST00000490841.2	ABI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	abl-interactor 1
chr8_-_102217515 Show fit	19.41	ENST00000520347.1 ENST00000523922.1 ENST00000520984.1	ZNF706 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 706
chr7_+_99971129 Show fit	19.29	ENST00000394000.2 ENST00000350573.2	PILRA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired immunoglobin-like type 2 receptor alpha
chr16_+_29465822 Show fit	19.23	ENST00000330181.5 ENST00000351581.4	SLX1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chrX_+_11777671 Show fit	19.22	ENST00000380693.3 ENST00000380692.2	MSL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	male-specific lethal 3 homolog (Drosophila)
chr5_+_35856951 Show fit	19.19	ENST00000303115.3 ENST00000343305.4 ENST00000506850.1 ENST00000511982.1	IL7R Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 7 receptor
chr14_+_23340822 Show fit	19.16	ENST00000359591.4	LRP10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	low density lipoprotein receptor-related protein 10
chr16_+_67063036 Show fit	19.12	ENST00000290858.6 ENST00000564034.1	CBFB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	core-binding factor, beta subunit
chr16_+_28505955 Show fit	19.12	ENST00000564831.1 ENST00000328423.5 ENST00000431282.1	APOBR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein B receptor
chr17_-_34417479 Show fit	19.00	ENST00000225245.5	CCL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-C motif) ligand 3
chr3_-_105588231 Show fit	18.88	ENST00000545639.1 ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1	CBLB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr4_-_103746924 Show fit	18.61	ENST00000505207.1 ENST00000502404.1 ENST00000507845.1	UBE2D3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin-conjugating enzyme E2D 3
chr7_+_99971068 Show fit	18.52	ENST00000198536.2 ENST00000453419.1	PILRA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired immunoglobin-like type 2 receptor alpha
chr10_-_27149792 Show fit	18.07	ENST00000376140.3 ENST00000376170.4	ABI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	abl-interactor 1
chr10_-_98031310 Show fit	18.02	ENST00000427367.2 ENST00000413476.2	BLNK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B-cell linker
chr19_+_48248779 Show fit	17.99	ENST00000246802.5	GLTSCR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glioma tumor suppressor candidate region gene 2
chr9_-_88969303 Show fit	17.94	ENST00000277141.6 ENST00000375963.3	ZCCHC6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, CCHC domain containing 6
chrX_+_118602363 Show fit	17.79	ENST00000317881.8	SLC25A5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr8_-_101965559 Show fit	17.79	ENST00000353245.3	YWHAZ Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_+_50344289 Show fit	17.66	ENST00000413698.1 ENST00000359197.5 ENST00000331340.3 ENST00000357364.4 ENST00000343574.5 ENST00000349824.4 ENST00000346667.4 ENST00000440768.2	IKZF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IKAROS family zinc finger 1 (Ikaros)
chr11_+_1874200 Show fit	17.64	ENST00000311604.3	LSP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphocyte-specific protein 1
chr5_-_142783694 Show fit	17.58	ENST00000394466.2	NR3C1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_202125219 Show fit	17.51	ENST00000323492.7	CASP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	caspase 8, apoptosis-related cysteine peptidase
chr12_-_120638902 Show fit	17.49	ENST00000551150.1 ENST00000313104.5 ENST00000547191.1 ENST00000546989.1 ENST00000392514.4 ENST00000228306.4 ENST00000550856.1	RPLP0 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein, large, P0
chr17_-_38721711 Show fit	17.46	ENST00000578085.1 ENST00000246657.2	CCR7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-C motif) receptor 7

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
38.3	153.2	GO:0071461	cellular response to redox state(GO:0071461)
29.7	89.0	GO:0070668	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
28.3	141.5	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
24.7	197.8	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
20.4	101.9	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
19.4	77.7	GO:0044027	hypermethylation of CpG island(GO:0044027)
18.5	55.6	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
15.9	63.8	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
15.7	47.1	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
15.2	45.5	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
14.7	73.4	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
14.3	57.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
13.7	54.8	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
12.2	73.0	GO:0000821	regulation of arginine metabolic process(GO:0000821)
12.0	12.0	GO:1904124	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
11.7	47.0	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
10.9	54.7	GO:0042631	cellular response to water deprivation(GO:0042631)
10.7	32.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
10.4	124.3	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
10.3	30.9	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
10.2	30.7	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
9.8	49.0	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
9.3	46.4	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
9.1	36.4	GO:2000538	regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
9.0	36.1	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
8.9	143.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
8.9	35.6	GO:0010796	regulation of multivesicular body size(GO:0010796)
8.8	43.9	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
8.4	25.3	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
7.8	23.5	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
7.8	147.6	GO:0035855	megakaryocyte development(GO:0035855)
7.7	30.8	GO:0008063	Toll signaling pathway(GO:0008063)
7.3	51.0	GO:0006226	dUMP biosynthetic process(GO:0006226)
7.2	36.0	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
7.1	21.4	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
7.0	27.9	GO:0021796	cerebral cortex regionalization(GO:0021796)
6.9	76.3	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
6.6	53.1	GO:0044351	macropinocytosis(GO:0044351)
6.5	104.2	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
6.1	127.9	GO:0071803	positive regulation of podosome assembly(GO:0071803)
5.8	46.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
5.7	34.3	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
5.6	16.7	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
5.5	22.2	GO:0016068	regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
5.5	44.1	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
5.2	25.8	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
5.1	36.0	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
5.1	15.2	GO:0002339	B cell selection(GO:0002339) B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
4.9	34.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
4.9	4.9	GO:0006624	vacuolar protein processing(GO:0006624)
4.9	24.4	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
4.8	33.6	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
4.6	18.5	GO:0030242	pexophagy(GO:0030242)
4.5	9.1	GO:0033029	regulation of neutrophil apoptotic process(GO:0033029)
4.4	13.3	GO:0007518	myoblast fate determination(GO:0007518)
4.4	21.8	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
4.4	13.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
4.3	30.1	GO:0032594	protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
4.2	25.4	GO:1904431	positive regulation of t-circle formation(GO:1904431)
4.2	25.2	GO:0016554	cytidine to uridine editing(GO:0016554)
4.2	41.7	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
4.1	12.3	GO:0006597	spermine biosynthetic process(GO:0006597)
4.0	16.1	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
4.0	12.0	GO:1903676	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
4.0	55.7	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
3.9	30.8	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
3.8	19.2	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
3.8	7.7	GO:0010572	positive regulation of platelet activation(GO:0010572)
3.8	19.0	GO:0043307	eosinophil activation(GO:0043307)
3.8	26.5	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
3.8	112.7	GO:0045730	respiratory burst(GO:0045730)
3.8	116.4	GO:0070207	protein homotrimerization(GO:0070207)
3.7	18.4	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
3.7	22.0	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
3.7	69.7	GO:0051014	actin filament severing(GO:0051014)
3.6	3.6	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
3.5	13.9	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
3.4	13.6	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
3.4	26.8	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
3.3	43.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
3.3	19.8	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
3.2	42.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
3.1	24.5	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
3.0	15.2	GO:0071895	odontoblast differentiation(GO:0071895)
3.0	12.0	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
3.0	17.8	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
2.9	20.5	GO:0050869	negative regulation of B cell activation(GO:0050869)
2.9	11.5	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
2.9	28.9	GO:0036066	protein O-linked fucosylation(GO:0036066)
2.8	56.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
2.8	8.4	GO:1905224	clathrin-coated pit assembly(GO:1905224)
2.7	40.8	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.7	8.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
2.7	38.1	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
2.7	48.2	GO:0002347	response to tumor cell(GO:0002347)
2.7	5.3	GO:0002384	hepatic immune response(GO:0002384)
2.6	10.3	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
2.5	10.2	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.5	5.0	GO:0045903	positive regulation of translational fidelity(GO:0045903)
2.5	10.0	GO:0000255	allantoin metabolic process(GO:0000255)
2.5	22.6	GO:0002315	marginal zone B cell differentiation(GO:0002315)
2.4	7.3	GO:1903772	ubiquitin-dependent endocytosis(GO:0070086) regulation of viral budding via host ESCRT complex(GO:1903772) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
2.4	14.6	GO:1903800	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
2.4	77.8	GO:0060216	definitive hemopoiesis(GO:0060216)
2.4	12.1	GO:0002634	regulation of germinal center formation(GO:0002634)
2.4	9.6	GO:0071802	negative regulation of podosome assembly(GO:0071802)
2.4	9.6	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
2.4	62.1	GO:0010447	response to acidic pH(GO:0010447)
2.3	58.3	GO:0016601	Rac protein signal transduction(GO:0016601)
2.3	18.0	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
2.2	55.4	GO:0043101	purine-containing compound salvage(GO:0043101)
2.2	37.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
2.1	20.9	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
2.0	6.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
2.0	5.9	GO:0001928	regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
2.0	37.4	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
2.0	3.9	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
1.9	21.4	GO:0061635	regulation of protein complex stability(GO:0061635)
1.9	5.8	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
1.9	42.0	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
1.8	25.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
1.8	24.8	GO:0050930	induction of positive chemotaxis(GO:0050930)
1.8	3.5	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
1.7	10.5	GO:0043316	cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
1.7	12.1	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
1.7	27.4	GO:0097320	membrane tubulation(GO:0097320)
1.7	23.9	GO:0051683	establishment of Golgi localization(GO:0051683)
1.7	13.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.7	8.5	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.7	1.7	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.7	5.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
1.7	210.8	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
1.7	18.5	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.7	36.4	GO:0008053	mitochondrial fusion(GO:0008053)
1.6	13.1	GO:0035897	proteolysis in other organism(GO:0035897)
1.6	94.5	GO:0045576	mast cell activation(GO:0045576)
1.6	25.6	GO:0071044	histone mRNA catabolic process(GO:0071044)
1.6	236.6	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.6	11.0	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
1.5	4.6	GO:0060380	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
1.5	4.5	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
1.5	7.4	GO:0072719	cellular response to cisplatin(GO:0072719)
1.5	59.5	GO:1901224	positive regulation of NIK/NF-kappaB signaling(GO:1901224)
1.4	19.9	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
1.4	5.6	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
1.4	13.8	GO:0071763	nuclear membrane organization(GO:0071763)
1.4	6.9	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
1.4	100.1	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
1.4	31.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
1.4	12.3	GO:0001887	selenium compound metabolic process(GO:0001887)
1.4	4.1	GO:0010957	negative regulation of vitamin D biosynthetic process(GO:0010957)
1.4	12.2	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
1.3	34.8	GO:0043984	histone H4-K16 acetylation(GO:0043984)
1.3	9.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
1.3	10.1	GO:0006116	NADH oxidation(GO:0006116)
1.3	13.9	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.3	8.8	GO:1902410	mitotic cytokinetic process(GO:1902410)
1.2	17.3	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
1.2	3.7	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.2	50.0	GO:0000188	inactivation of MAPK activity(GO:0000188)
1.2	8.4	GO:0021847	ventricular zone neuroblast division(GO:0021847)
1.2	3.6	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
1.2	13.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
1.2	8.2	GO:0071569	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.2	17.5	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
1.2	7.0	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
1.2	29.2	GO:0007202	activation of phospholipase C activity(GO:0007202)
1.2	5.8	GO:0006642	triglyceride mobilization(GO:0006642)
1.2	8.1	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
1.1	3.4	GO:0018201	N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
1.1	27.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
1.1	19.1	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
1.1	16.8	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
1.1	53.4	GO:0042100	B cell proliferation(GO:0042100)
1.1	7.8	GO:2001138	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
1.1	3.3	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.1	7.6	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
1.1	6.5	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
1.1	88.6	GO:0050672	negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
1.1	4.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
1.1	153.5	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
1.1	14.9	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
1.0	12.1	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
1.0	5.0	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.0	17.7	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
1.0	10.8	GO:0010815	bradykinin catabolic process(GO:0010815)
1.0	12.5	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
1.0	5.7	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.9	12.9	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.9	28.5	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.9	26.7	GO:0006266	DNA ligation(GO:0006266)
0.9	4.5	GO:0019230	proprioception(GO:0019230)
0.9	11.5	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.9	6.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.9	58.5	GO:0070527	platelet aggregation(GO:0070527)
0.9	2.6	GO:0060613	fat pad development(GO:0060613)
0.8	5.0	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.8	11.5	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.8	12.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.8	29.5	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.8	14.6	GO:0016180	snRNA processing(GO:0016180)
0.8	12.0	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.8	1.5	GO:0061056	sclerotome development(GO:0061056)
0.8	12.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.7	95.8	GO:0007338	single fertilization(GO:0007338)
0.7	18.3	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.7	5.8	GO:0002517	T cell tolerance induction(GO:0002517)
0.7	104.6	GO:0043484	regulation of RNA splicing(GO:0043484)
0.7	7.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.7	22.2	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.7	3.5	GO:0021759	globus pallidus development(GO:0021759)
0.7	9.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.7	9.6	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.7	2.0	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.7	2.0	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.6	5.2	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.6	21.8	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.6	6.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.6	35.1	GO:0030183	B cell differentiation(GO:0030183)
0.6	0.6	GO:2000137	cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.6	24.1	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.6	2.8	GO:0051182	coenzyme transport(GO:0051182)
0.6	6.2	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.6	3.3	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.5	24.2	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.5	15.5	GO:0006491	N-glycan processing(GO:0006491)
0.5	20.8	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.5	4.8	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.5	11.5	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.5	4.1	GO:0001780	neutrophil homeostasis(GO:0001780)
0.5	15.1	GO:0046039	GTP metabolic process(GO:0046039)
0.5	9.2	GO:0007035	vacuolar acidification(GO:0007035)
0.5	7.2	GO:0038092	nodal signaling pathway(GO:0038092)
0.4	0.8	GO:0007296	vitellogenesis(GO:0007296)
0.4	4.4	GO:0045116	protein neddylation(GO:0045116)
0.4	2.4	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.4	1.9	GO:0050729	positive regulation of inflammatory response(GO:0050729)
0.4	1.5	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.4	17.6	GO:0006968	cellular defense response(GO:0006968)
0.4	5.5	GO:0017145	stem cell division(GO:0017145)
0.4	78.3	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.4	7.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.4	1.1	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.4	2.8	GO:0038203	TORC2 signaling(GO:0038203)
0.3	3.5	GO:0040016	embryonic cleavage(GO:0040016)
0.3	39.5	GO:0034605	cellular response to heat(GO:0034605)
0.3	11.0	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.3	2.5	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.3	6.4	GO:0003334	keratinocyte development(GO:0003334)
0.3	5.5	GO:0071539	protein localization to centrosome(GO:0071539)
0.3	43.2	GO:0006338	chromatin remodeling(GO:0006338)
0.3	5.5	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.3	1.8	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3	2.6	GO:0034508	centromere complex assembly(GO:0034508)
0.3	0.3	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.3	17.7	GO:0030218	erythrocyte differentiation(GO:0030218)
0.3	20.4	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.3	9.3	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.3	8.5	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.3	0.5	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.3	20.2	GO:0045727	positive regulation of translation(GO:0045727)
0.2	4.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.2	4.0	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.2	4.6	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2	9.3	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.2	4.4	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.2	17.7	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	1.4	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.2	8.4	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.2	0.8	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.2	8.2	GO:0006446	regulation of translational initiation(GO:0006446)
0.2	4.7	GO:0006298	mismatch repair(GO:0006298)
0.2	6.1	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.2	4.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.2	2.3	GO:0060117	auditory receptor cell development(GO:0060117)
0.2	7.1	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.2	2.1	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.2	11.8	GO:0042113	B cell activation(GO:0042113)
0.2	0.9	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.2	1.9	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.2	3.5	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.2	2.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.2	0.5	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.2	1.5	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.2	23.0	GO:0002576	platelet degranulation(GO:0002576)
0.2	1.9	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.2	9.2	GO:0048678	response to axon injury(GO:0048678)
0.2	40.6	GO:0051056	regulation of small GTPase mediated signal transduction(GO:0051056)
0.2	6.1	GO:0016266	O-glycan processing(GO:0016266)
0.1	8.0	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	1.5	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.7	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.1	3.7	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	1.7	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1	5.6	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.1	1.6	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.3	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
0.1	2.1	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	1.4	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	3.5	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.1	0.6	GO:0097480	synaptic vesicle transport(GO:0048489) establishment of synaptic vesicle localization(GO:0097480)
0.1	1.6	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	1.0	GO:0042108	positive regulation of cytokine biosynthetic process(GO:0042108)
0.1	0.4	GO:0032048	cardiolipin metabolic process(GO:0032048) cardiolipin acyl-chain remodeling(GO:0035965)
0.1	0.7	GO:0036507	protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) endoplasmic reticulum mannose trimming(GO:1904380)
0.1	0.2	GO:1904327	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1	1.6	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.9	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659)
0.1	0.8	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	1.0	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.4	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.3	GO:0048305	immunoglobulin secretion(GO:0048305)
0.0	0.6	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	10.4	GO:0051260	protein homooligomerization(GO:0051260)
0.0	1.0	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	2.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	2.9	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	1.5	GO:0048278	vesicle docking(GO:0048278)
0.0	0.6	GO:0021983	pituitary gland development(GO:0021983)
0.0	0.4	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.0	0.2	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	1.0	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	2.1	GO:0001503	ossification(GO:0001503)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.6	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	1.1	GO:0008033	tRNA processing(GO:0008033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
21.5	236.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
19.4	155.2	GO:0032010	phagolysosome(GO:0032010)
17.8	89.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
15.9	63.8	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
15.3	92.0	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
14.5	116.2	GO:1990111	spermatoproteasome complex(GO:1990111)
11.1	55.4	GO:0036398	TCR signalosome(GO:0036398)
9.6	19.1	GO:0042627	chylomicron(GO:0042627)
9.2	55.4	GO:1902560	GMP reductase complex(GO:1902560)
9.0	125.9	GO:0031209	SCAR complex(GO:0031209)
8.2	164.3	GO:0001891	phagocytic cup(GO:0001891)
7.8	102.0	GO:0043020	NADPH oxidase complex(GO:0043020)
7.1	49.6	GO:0036021	endolysosome lumen(GO:0036021)
6.9	27.5	GO:0097422	tubular endosome(GO:0097422)
6.8	20.5	GO:0071159	NF-kappaB complex(GO:0071159)
6.4	31.8	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
6.1	6.1	GO:1902911	serine/threonine protein kinase complex(GO:1902554) protein kinase complex(GO:1902911)
5.7	34.3	GO:0071817	MMXD complex(GO:0071817)
5.6	22.4	GO:0043625	delta DNA polymerase complex(GO:0043625)
5.4	26.8	GO:0098837	postsynaptic recycling endosome(GO:0098837)
5.3	37.1	GO:0019815	B cell receptor complex(GO:0019815)
5.0	95.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
5.0	50.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
5.0	34.8	GO:0072487	MSL complex(GO:0072487)
4.2	12.5	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
4.1	69.7	GO:0032059	bleb(GO:0032059)
4.1	52.7	GO:0097433	dense body(GO:0097433)
4.0	216.8	GO:0001772	immunological synapse(GO:0001772)
3.9	42.6	GO:0031010	ISWI-type complex(GO:0031010)
3.8	15.2	GO:0030905	retromer, tubulation complex(GO:0030905)
3.8	11.4	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
3.7	22.4	GO:0008537	proteasome activator complex(GO:0008537)
3.6	32.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
3.3	10.0	GO:0070195	growth hormone receptor complex(GO:0070195)
3.3	49.8	GO:0008290	F-actin capping protein complex(GO:0008290)
3.2	16.1	GO:0042643	actomyosin, actin portion(GO:0042643)
3.1	12.2	GO:0005687	U4 snRNP(GO:0005687)
3.0	21.0	GO:0044194	cytolytic granule(GO:0044194)
2.9	46.9	GO:0016461	unconventional myosin complex(GO:0016461)
2.8	22.6	GO:0042382	paraspeckles(GO:0042382)
2.8	22.5	GO:0097504	Gemini of coiled bodies(GO:0097504)
2.5	44.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
2.5	9.9	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
2.2	32.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
2.2	13.1	GO:1990037	Lewy body core(GO:1990037)
2.2	167.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
2.1	29.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
2.0	13.9	GO:0030870	Mre11 complex(GO:0030870)
1.9	13.6	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.9	13.3	GO:0016272	prefoldin complex(GO:0016272)
1.9	13.3	GO:0070765	gamma-secretase complex(GO:0070765)
1.9	7.5	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
1.8	10.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
1.7	55.0	GO:0005685	U1 snRNP(GO:0005685)
1.6	8.2	GO:0000125	PCAF complex(GO:0000125)
1.6	14.6	GO:0032039	integrator complex(GO:0032039)
1.6	4.8	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.6	1.6	GO:0034719	SMN-Sm protein complex(GO:0034719)
1.6	11.0	GO:0097452	GAIT complex(GO:0097452)
1.5	132.6	GO:0035580	specific granule lumen(GO:0035580)
1.5	4.5	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
1.4	5.8	GO:0030915	Smc5-Smc6 complex(GO:0030915)
1.4	15.2	GO:1990907	beta-catenin-TCF complex(GO:1990907)
1.4	6.9	GO:0032021	NELF complex(GO:0032021)
1.4	8.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
1.3	94.3	GO:0035577	azurophil granule membrane(GO:0035577)
1.3	5.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.3	5.3	GO:0032044	DSIF complex(GO:0032044)
1.2	8.7	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
1.2	16.1	GO:0005577	fibrinogen complex(GO:0005577)
1.2	45.7	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
1.2	5.9	GO:0033263	CORVET complex(GO:0033263)
1.2	15.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
1.1	11.9	GO:0016602	CCAAT-binding factor complex(GO:0016602)
1.1	7.6	GO:0017119	Golgi transport complex(GO:0017119)
1.1	45.2	GO:0002102	podosome(GO:0002102)
1.1	15.1	GO:0042588	zymogen granule(GO:0042588)
1.1	8.4	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.0	7.3	GO:0000813	ESCRT I complex(GO:0000813)
1.0	113.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
1.0	5.0	GO:0034457	Mpp10 complex(GO:0034457)
1.0	17.5	GO:0097342	ripoptosome(GO:0097342)
1.0	11.6	GO:0030008	TRAPP complex(GO:0030008)
1.0	4.8	GO:0032009	early phagosome(GO:0032009)
1.0	5.7	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.9	12.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.9	9.3	GO:0005916	fascia adherens(GO:0005916)
0.9	3.6	GO:0055087	Ski complex(GO:0055087)
0.9	274.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.9	7.0	GO:0035976	AP1 complex(GO:0035976)
0.9	7.0	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.8	5.0	GO:1990130	Iml1 complex(GO:1990130)
0.8	5.0	GO:0005865	striated muscle thin filament(GO:0005865)
0.8	112.0	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.8	5.7	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.8	6.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.8	4.8	GO:0000322	storage vacuole(GO:0000322)
0.8	2.4	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.8	2.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.7	12.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.7	69.9	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.7	12.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.7	5.6	GO:0071439	clathrin complex(GO:0071439)
0.7	50.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.7	8.8	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7	34.3	GO:0043198	dendritic shaft(GO:0043198)
0.7	53.9	GO:0034707	chloride channel complex(GO:0034707)
0.7	97.8	GO:0005795	Golgi stack(GO:0005795)
0.7	6.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.6	1.9	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.6	100.5	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.6	34.0	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.6	18.7	GO:0000793	condensed chromosome(GO:0000793)
0.5	21.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.5	18.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.5	11.5	GO:0031105	septin complex(GO:0031105)
0.5	14.9	GO:0005720	nuclear heterochromatin(GO:0005720)
0.5	28.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.5	2.4	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.5	12.9	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.5	7.7	GO:0036452	ESCRT complex(GO:0036452)
0.4	10.8	GO:0071564	npBAF complex(GO:0071564)
0.4	1.7	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4	27.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.4	9.0	GO:0031201	SNARE complex(GO:0031201)
0.4	4.0	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.4	6.2	GO:0097225	sperm midpiece(GO:0097225)
0.4	34.2	GO:0005884	actin filament(GO:0005884)
0.4	2.1	GO:0035371	microtubule plus-end(GO:0035371)
0.3	29.2	GO:0005758	mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.3	2.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.3	122.8	GO:0016607	nuclear speck(GO:0016607)
0.3	6.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.3	53.4	GO:0030667	secretory granule membrane(GO:0030667)
0.3	3.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.3	22.3	GO:0005905	clathrin-coated pit(GO:0005905)
0.3	2.9	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.3	5.1	GO:0000242	pericentriolar material(GO:0000242)
0.3	13.3	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3	7.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.3	3.2	GO:0032433	filopodium tip(GO:0032433)
0.3	22.3	GO:0035578	azurophil granule lumen(GO:0035578)
0.3	145.6	GO:0000139	Golgi membrane(GO:0000139)
0.2	30.9	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2	6.4	GO:0009925	basal plasma membrane(GO:0009925)
0.2	10.6	GO:0005902	microvillus(GO:0005902)
0.2	22.9	GO:0016605	PML body(GO:0016605)
0.2	52.0	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2	4.5	GO:0000421	autophagosome membrane(GO:0000421)
0.2	2.8	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.2	3.2	GO:0000145	exocyst(GO:0000145)
0.2	4.3	GO:0005770	late endosome(GO:0005770)
0.2	17.8	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.2	9.5	GO:0005923	bicellular tight junction(GO:0005923)
0.2	4.1	GO:0000930	gamma-tubulin complex(GO:0000930)
0.2	2.3	GO:0032420	stereocilium(GO:0032420)
0.2	0.6	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.1	1.1	GO:0070187	telosome(GO:0070187)
0.1	8.9	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.1	9.5	GO:0005667	transcription factor complex(GO:0005667)
0.1	0.7	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	548.0	GO:0005829	cytosol(GO:0005829)
0.1	4.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	1.5	GO:0032587	ruffle membrane(GO:0032587)
0.1	8.7	GO:0031965	nuclear membrane(GO:0031965)
0.1	0.5	GO:0035861	site of double-strand break(GO:0035861)
0.1	2.3	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.7	GO:1904115	axon cytoplasm(GO:1904115)
0.0	5.0	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	3.8	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529)
0.0	4.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.3	GO:0031093	platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.5	55.6	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
16.3	49.0	GO:0031859	platelet activating factor receptor binding(GO:0031859)
15.3	153.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
13.9	41.8	GO:0004917	interleukin-7 receptor activity(GO:0004917)
13.8	96.6	GO:0043208	glycosphingolipid binding(GO:0043208)
13.3	133.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
13.1	92.0	GO:0030369	ICAM-3 receptor activity(GO:0030369)
12.8	76.6	GO:0042610	CD8 receptor binding(GO:0042610)
12.7	51.0	GO:0004132	dCMP deaminase activity(GO:0004132)
10.9	32.8	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
10.7	74.9	GO:0042608	T cell receptor binding(GO:0042608)
10.4	31.2	GO:0001069	regulatory region RNA binding(GO:0001069)
9.2	55.4	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
9.2	27.5	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
8.4	25.3	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
8.1	146.4	GO:0005522	profilin binding(GO:0005522)
7.8	211.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
7.1	21.4	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
7.1	77.7	GO:0051525	NFAT protein binding(GO:0051525)
6.6	19.9	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
6.6	26.3	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
6.6	19.7	GO:0017108	5'-flap endonuclease activity(GO:0017108)
6.4	25.6	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
6.3	38.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
6.3	69.0	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
6.0	102.0	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
5.4	26.8	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
5.1	56.0	GO:0019869	chloride channel inhibitor activity(GO:0019869)
4.5	67.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
4.1	57.9	GO:0030957	Tat protein binding(GO:0030957)
4.1	12.3	GO:0098625	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
3.9	116.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
3.8	15.3	GO:0019770	IgG receptor activity(GO:0019770)
3.8	11.4	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
3.8	19.0	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
3.7	56.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
3.7	118.5	GO:0070064	proline-rich region binding(GO:0070064)
3.7	22.0	GO:0035800	deubiquitinase activator activity(GO:0035800)
3.5	28.0	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
3.5	17.5	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
3.4	6.8	GO:0019763	immunoglobulin receptor activity(GO:0019763)
3.4	43.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
3.2	22.4	GO:0061133	endopeptidase activator activity(GO:0061133)
3.0	15.2	GO:1990460	leptin receptor binding(GO:1990460)
3.0	57.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.9	132.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
2.9	23.5	GO:0016842	amidine-lyase activity(GO:0016842)
2.9	8.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
2.9	8.7	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.9	11.5	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
2.7	19.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
2.7	31.8	GO:0033691	sialic acid binding(GO:0033691)
2.6	10.6	GO:0019826	oxygen sensor activity(GO:0019826)
2.5	20.4	GO:1990405	protein antigen binding(GO:1990405)
2.5	10.2	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.5	17.7	GO:0035614	snRNA stem-loop binding(GO:0035614)
2.5	74.9	GO:0023026	MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
2.5	32.1	GO:0019957	C-C chemokine binding(GO:0019957)
2.4	14.6	GO:0035500	MH2 domain binding(GO:0035500)
2.4	21.6	GO:0043426	MRF binding(GO:0043426)
2.4	31.0	GO:0045294	alpha-catenin binding(GO:0045294)
2.4	40.0	GO:0004143	diacylglycerol kinase activity(GO:0004143)
2.3	7.0	GO:0005047	signal recognition particle binding(GO:0005047)
2.3	57.9	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
2.3	142.9	GO:1990782	protein tyrosine kinase binding(GO:1990782)
2.2	56.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
2.2	44.8	GO:0051400	BH domain binding(GO:0051400)
2.2	31.2	GO:0003680	AT DNA binding(GO:0003680)
2.2	33.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
2.2	12.9	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
2.1	29.6	GO:0019864	IgG binding(GO:0019864)
2.1	16.6	GO:0008266	poly(U) RNA binding(GO:0008266)
2.0	12.1	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
1.9	13.6	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.9	3.9	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.9	7.8	GO:0001632	leukotriene B4 receptor activity(GO:0001632)
1.9	7.5	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.9	9.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.8	5.5	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
1.8	5.3	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.8	8.8	GO:0004906	interferon-gamma receptor activity(GO:0004906)
1.8	7.0	GO:0070051	fibrinogen binding(GO:0070051)
1.7	12.2	GO:0030621	U4 snRNA binding(GO:0030621)
1.7	13.9	GO:0070087	chromo shadow domain binding(GO:0070087)
1.7	6.9	GO:0016936	galactoside binding(GO:0016936)
1.7	15.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
1.7	8.4	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
1.7	11.6	GO:1990226	histone methyltransferase binding(GO:1990226)
1.7	24.8	GO:0042609	CD4 receptor binding(GO:0042609)
1.6	8.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.6	4.8	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.6	73.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
1.6	28.5	GO:0035497	cAMP response element binding(GO:0035497)
1.6	31.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.6	17.1	GO:0034452	dynactin binding(GO:0034452)
1.5	9.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.5	6.0	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.5	28.5	GO:0004697	protein kinase C activity(GO:0004697)
1.5	32.2	GO:0000339	RNA cap binding(GO:0000339)
1.5	49.6	GO:0043236	laminin binding(GO:0043236)
1.4	37.3	GO:0031489	myosin V binding(GO:0031489)
1.4	5.7	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
1.4	8.4	GO:0004167	dopachrome isomerase activity(GO:0004167)
1.4	20.9	GO:0043274	phospholipase binding(GO:0043274)
1.4	13.9	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.3	44.3	GO:0042288	MHC class I protein binding(GO:0042288)
1.3	5.3	GO:0017160	Ral GTPase binding(GO:0017160)
1.2	14.9	GO:0045159	myosin II binding(GO:0045159)
1.2	3.6	GO:0004967	glucagon receptor activity(GO:0004967)
1.2	38.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
1.2	62.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.2	112.6	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
1.2	40.1	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
1.2	38.9	GO:0070717	poly-purine tract binding(GO:0070717)
1.1	6.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.1	3.4	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.1	19.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
1.1	6.7	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
1.1	9.9	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
1.1	66.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
1.0	11.4	GO:0005049	nuclear export signal receptor activity(GO:0005049)
1.0	3.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
1.0	49.2	GO:0004364	glutathione transferase activity(GO:0004364)
1.0	24.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.9	15.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.9	93.6	GO:0017124	SH3 domain binding(GO:0017124)
0.9	20.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.9	2.8	GO:0051185	coenzyme transporter activity(GO:0051185)
0.9	12.0	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.9	211.5	GO:0051015	actin filament binding(GO:0051015)
0.9	8.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.9	52.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.9	6.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.9	4.4	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.9	13.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.9	21.0	GO:0022829	wide pore channel activity(GO:0022829)
0.9	19.1	GO:0005521	lamin binding(GO:0005521)
0.9	15.6	GO:0017091	AU-rich element binding(GO:0017091)
0.8	18.7	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.8	31.4	GO:0017025	TBP-class protein binding(GO:0017025)
0.8	5.7	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.8	109.6	GO:0005178	integrin binding(GO:0005178)
0.8	21.6	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.8	4.7	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.8	241.3	GO:0005096	GTPase activator activity(GO:0005096)
0.8	22.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.8	25.5	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.8	7.7	GO:0046790	virion binding(GO:0046790)
0.8	4.6	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.8	13.6	GO:0097602	cullin family protein binding(GO:0097602)
0.7	15.4	GO:0046961	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.7	11.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.7	3.6	GO:0001594	trace-amine receptor activity(GO:0001594)
0.7	7.2	GO:0042287	MHC protein binding(GO:0042287)
0.7	148.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.7	39.5	GO:0035064	methylated histone binding(GO:0035064)
0.7	3.3	GO:0019003	GDP binding(GO:0019003)
0.6	187.2	GO:0003924	GTPase activity(GO:0003924)
0.6	18.0	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.6	2.5	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.6	8.5	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
0.6	1.7	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.5	4.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.5	2.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.5	18.6	GO:0042162	telomeric DNA binding(GO:0042162)
0.5	4.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.5	12.4	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.5	28.4	GO:0004402	histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.5	7.0	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.5	5.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.5	10.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.5	2.9	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.5	7.6	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.5	18.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.5	52.0	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.5	14.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4	2.2	GO:0050693	LBD domain binding(GO:0050693)
0.4	4.3	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.4	7.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4	0.8	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.4	6.1	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4	9.5	GO:0051393	alpha-actinin binding(GO:0051393)
0.4	2.0	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4	48.8	GO:0047485	protein N-terminus binding(GO:0047485)
0.4	9.7	GO:0001671	ATPase activator activity(GO:0001671)
0.4	9.6	GO:0046965	retinoid X receptor binding(GO:0046965)
0.4	1.9	GO:0034511	U3 snoRNA binding(GO:0034511)
0.4	17.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.4	22.1	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.4	4.7	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.4	12.9	GO:0004407	histone deacetylase activity(GO:0004407)
0.4	1.1	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.3	17.8	GO:0003743	translation initiation factor activity(GO:0003743)
0.3	0.7	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.3	5.8	GO:0035004	phosphatidylinositol 3-kinase activity(GO:0035004) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.3	84.2	GO:0003713	transcription coactivator activity(GO:0003713)
0.3	1.5	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.3	3.5	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3	21.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.3	13.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3	5.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.2	4.0	GO:0004526	ribonuclease P activity(GO:0004526)
0.2	29.3	GO:0003774	motor activity(GO:0003774)
0.2	9.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.2	0.7	GO:0050811	GABA receptor binding(GO:0050811)
0.2	9.4	GO:0005548	phospholipid transporter activity(GO:0005548)
0.2	3.7	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	2.3	GO:0071889	14-3-3 protein binding(GO:0071889)
0.2	0.7	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2	6.3	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2	4.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	41.8	GO:0003712	transcription cofactor activity(GO:0003712)
0.2	3.9	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	1.7	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	2.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	1.7	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	2.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	2.4	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	1.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.6	GO:0036122	BMP binding(GO:0036122)
0.1	4.1	GO:0004896	cytokine receptor activity(GO:0004896)
0.1	15.4	GO:0003682	chromatin binding(GO:0003682)
0.0	2.1	GO:0004386	helicase activity(GO:0004386)
0.0	0.5	GO:0030346	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) protein phosphatase 2B binding(GO:0030346)
0.0	3.0	GO:0000149	SNARE binding(GO:0000149)
0.0	1.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	2.0	GO:0044325	ion channel binding(GO:0044325)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.7	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.4	684.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
6.1	280.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
4.7	407.9	PID RAC1 PATHWAY	RAC1 signaling pathway
4.5	316.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
4.3	225.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
2.9	17.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
2.8	42.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
2.6	186.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
2.6	23.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
2.5	73.9	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
2.1	49.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
2.1	33.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
2.1	150.5	PID ILK PATHWAY	Integrin-linked kinase signaling
2.0	66.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
1.7	47.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
1.7	163.6	PID CMYB PATHWAY	C-MYB transcription factor network
1.6	16.4	PID S1P S1P4 PATHWAY	S1P4 pathway
1.6	61.6	PID BCR 5PATHWAY	BCR signaling pathway
1.5	20.4	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
1.4	211.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
1.3	38.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
1.2	32.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
1.2	29.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
1.1	27.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
1.1	5.6	PID IL3 PATHWAY	IL3-mediated signaling events
1.1	15.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.1	17.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
1.0	9.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
1.0	35.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.9	22.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.9	5.3	ST STAT3 PATHWAY	STAT3 Pathway
0.9	17.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.8	3.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.7	51.9	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.7	22.1	PID IL12 2PATHWAY	IL12-mediated signaling events
0.6	7.0	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.5	54.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.5	12.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.4	39.1	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.4	19.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3	5.9	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.3	11.0	PID BARD1 PATHWAY	BARD1 signaling events
0.3	10.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.3	7.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.3	5.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	10.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.2	4.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	2.9	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	3.1	PID ATR PATHWAY	ATR signaling pathway
0.1	4.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	5.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	1.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	3.9	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	3.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.1	PID E2F PATHWAY	E2F transcription factor network
0.0	1.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.6	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	2.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.7	PID P73PATHWAY	p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.4	98.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
15.9	429.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
5.8	253.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
5.4	310.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
5.0	49.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
4.3	349.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
4.2	67.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
4.0	19.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
3.2	41.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
2.9	17.5	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
2.7	52.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
2.6	28.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
2.4	65.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
2.2	368.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
2.2	315.2	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
2.2	55.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
2.2	44.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
2.2	50.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
2.0	47.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
2.0	23.9	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
2.0	61.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.9	22.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
1.9	54.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.8	59.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.8	38.8	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
1.7	65.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.5	38.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
1.5	21.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
1.5	51.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
1.4	56.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
1.4	16.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
1.4	23.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.4	103.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.3	22.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
1.3	49.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.3	31.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.3	22.9	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
1.3	25.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
1.3	40.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.2	9.9	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
1.2	7.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
1.2	46.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
1.2	28.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
1.1	66.2	REACTOME G1 PHASE	Genes involved in G1 Phase
1.1	6.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
1.1	5.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
1.0	8.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
1.0	13.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
1.0	101.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
1.0	45.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.9	16.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.8	124.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.8	13.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.7	8.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.7	10.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.7	13.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.7	14.0	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.7	10.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.6	5.7	REACTOME TRANSCRIPTION COUPLED NER TC NER	Genes involved in Transcription-coupled NER (TC-NER)
0.6	16.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.6	10.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.6	5.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.6	11.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.5	6.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.5	21.7	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.5	5.9	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.5	12.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.5	17.0	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5	22.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.4	10.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.4	10.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.4	9.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.4	7.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.4	5.8	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.4	15.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.3	26.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.3	6.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.3	2.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.3	17.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	14.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.2	7.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	12.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	5.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	4.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.2	17.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	3.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	5.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	3.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	1.1	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.1	2.1	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	5.8	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.1	1.5	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	1.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	2.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	1.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	3.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen