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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TAF1

Z-value: 5.41

Motif logo

Transcription factors associated with TAF1

Gene Symbol Gene ID Gene Info
ENSG00000147133.11 TATA-box binding protein associated factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TAF1hg19_v2_chrX_+_70586082_70586114-0.522.9e-16Click!

Activity profile of TAF1 motif

Sorted Z-values of TAF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_37679803 180.20 ENST00000379800.3
casein kinase 1, alpha 1-like
chr20_-_49547731 112.10 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr19_-_13044494 106.06 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
phenylalanyl-tRNA synthetase, alpha subunit
chr8_+_98656336 103.19 ENST00000336273.3
metadherin
chr2_+_114647504 102.20 ENST00000263238.2
ARP3 actin-related protein 3 homolog (yeast)
chr12_-_49075941 100.40 ENST00000553086.1
ENST00000548304.1
KAT8 regulatory NSL complex subunit 2
chr11_-_10879593 97.17 ENST00000528289.1
ENST00000432999.2
zinc finger, BED-type containing 5
chr14_+_78174414 94.50 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SRA stem-loop interacting RNA binding protein
chr1_+_93544821 92.97 ENST00000370303.4
metal response element binding transcription factor 2
chr19_+_8509842 91.92 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
heterogeneous nuclear ribonucleoprotein M
chr5_-_150284532 91.75 ENST00000394226.2
ENST00000446148.2
ENST00000274599.5
ENST00000418587.2
zinc finger protein 300
chr1_-_155904187 90.75 ENST00000368321.3
ENST00000368320.3
KIAA0907
chr14_+_103801140 89.83 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
eukaryotic translation initiation factor 5
chrX_+_123095155 89.81 ENST00000371160.1
ENST00000435103.1
stromal antigen 2
chr14_-_69864993 89.57 ENST00000555373.1
enhancer of rudimentary homolog (Drosophila)
chr9_+_131452239 89.25 ENST00000372688.4
ENST00000372686.5
SET nuclear oncogene
chr5_-_150284351 86.92 ENST00000427179.1
zinc finger protein 300
chr17_-_62502022 86.55 ENST00000578804.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr5_-_180670880 85.83 ENST00000511566.1
ENST00000511900.1
ENST00000504726.1
ENST00000512968.1
ENST00000376817.4
ENST00000513027.1
ENST00000503081.1
ENST00000456394.2
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr19_+_797392 85.28 ENST00000350092.4
ENST00000349038.4
ENST00000586481.1
ENST00000585535.1
polypyrimidine tract binding protein 1
chr19_+_797443 85.19 ENST00000394601.4
ENST00000589575.1
polypyrimidine tract binding protein 1
chr12_+_7079944 84.50 ENST00000261406.6
EMG1 N1-specific pseudouridine methyltransferase
chr6_+_36562132 84.16 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chr11_-_10879572 81.65 ENST00000413761.2
zinc finger, BED-type containing 5
chr12_-_49076002 79.17 ENST00000357861.3
ENST00000550347.1
ENST00000420613.2
ENST00000550931.1
ENST00000550870.1
KAT8 regulatory NSL complex subunit 2
chrX_+_48433326 78.81 ENST00000376755.1
RNA binding motif (RNP1, RRM) protein 3
chr8_+_98656693 74.62 ENST00000519934.1
metadherin
chr5_-_71616043 73.72 ENST00000508863.2
ENST00000522095.1
ENST00000513900.1
ENST00000515404.1
ENST00000457646.4
ENST00000261413.5
mitochondrial ribosomal protein S27
chrX_-_109561294 73.23 ENST00000372059.2
ENST00000262844.5
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_+_153606532 73.11 ENST00000403433.1
chromatin target of PRMT1
chr12_-_123011536 71.92 ENST00000331738.7
ENST00000354654.2
arginine/serine-rich coiled-coil 2
chr20_-_49547910 71.85 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr14_+_23235886 68.83 ENST00000604262.1
ENST00000431881.2
ENST00000412791.1
ENST00000358043.5
oxidase (cytochrome c) assembly 1-like
chr20_-_524415 68.67 ENST00000400217.2
casein kinase 2, alpha 1 polypeptide
chr5_-_180671172 68.63 ENST00000512805.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr1_+_62902308 68.23 ENST00000339950.4
ubiquitin specific peptidase 1
chr17_-_79481666 67.65 ENST00000575659.1
actin, gamma 1
chr1_+_46769303 67.00 ENST00000311672.5
ubiquinol-cytochrome c reductase hinge protein
chr3_+_160117087 66.88 ENST00000357388.3
structural maintenance of chromosomes 4
chr17_+_73257945 66.13 ENST00000579002.1
mitochondrial ribosomal protein S7
chr3_+_160117418 65.95 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
structural maintenance of chromosomes 4
chr15_-_89010607 65.64 ENST00000312475.4
mitochondrial ribosomal protein L46
chr19_+_38865398 65.37 ENST00000585598.1
ENST00000602911.1
ENST00000592561.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr11_+_4116054 65.24 ENST00000423050.2
ribonucleotide reductase M1
chr6_-_86352982 64.81 ENST00000369622.3
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_1303462 64.48 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr17_+_73257742 64.39 ENST00000579761.1
ENST00000245539.6
mitochondrial ribosomal protein S7
chr11_+_65686802 63.99 ENST00000376991.2
DR1-associated protein 1 (negative cofactor 2 alpha)
chr12_-_82752565 63.78 ENST00000256151.7
coiled-coil domain containing 59
chr16_-_28223166 63.18 ENST00000304658.5
exportin 6
chr4_-_83350580 63.10 ENST00000349655.4
ENST00000602300.1
heterogeneous nuclear ribonucleoprotein D-like
chr11_+_4116005 62.82 ENST00000300738.5
ribonucleotide reductase M1
chr21_-_44527613 62.78 ENST00000380276.2
ENST00000398137.1
ENST00000291552.4
U2 small nuclear RNA auxiliary factor 1
chr6_+_32940436 62.62 ENST00000395287.1
bromodomain containing 2
chr16_+_67596310 62.35 ENST00000264010.4
ENST00000401394.1
CCCTC-binding factor (zinc finger protein)
chr1_+_113161778 61.35 ENST00000263168.3
capping protein (actin filament) muscle Z-line, alpha 1
chrX_+_48432892 61.21 ENST00000376759.3
ENST00000430348.2
RNA binding motif (RNP1, RRM) protein 3
chr6_-_109703600 60.98 ENST00000512821.1
CD164 molecule, sialomucin
chr19_+_38865176 60.78 ENST00000215071.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr6_+_155054459 60.77 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
SR-related CTD-associated factor 8
chr17_-_56084578 60.60 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
serine/arginine-rich splicing factor 1
chr3_+_38206975 60.56 ENST00000446845.1
ENST00000311806.3
oxidative stress responsive 1
chr6_-_8102279 60.43 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr15_+_40453204 60.34 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chr12_+_93861264 60.22 ENST00000549982.1
ENST00000361630.2
mitochondrial ribosomal protein L42
chr15_-_59225758 59.81 ENST00000558486.1
ENST00000560682.1
ENST00000249736.7
ENST00000559880.1
ENST00000536328.1
SAFB-like, transcription modulator
chr11_+_65686952 59.80 ENST00000527119.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chrX_+_19373700 59.28 ENST00000379804.1
pyruvate dehydrogenase (lipoamide) alpha 1
chr1_+_46049706 58.37 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
nuclear autoantigenic sperm protein (histone-binding)
chrX_+_70503037 58.33 ENST00000535149.1
non-POU domain containing, octamer-binding
chr1_-_149900122 57.95 ENST00000271628.8
splicing factor 3b, subunit 4, 49kDa
chr12_+_93861282 57.15 ENST00000552217.1
ENST00000393128.4
ENST00000547098.1
mitochondrial ribosomal protein L42
chr12_-_111180644 57.08 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
protein phosphatase 1, catalytic subunit, gamma isozyme
chr1_+_155657737 57.00 ENST00000471642.2
ENST00000471214.1
death associated protein 3
chr5_+_32531893 56.92 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr1_+_33116765 56.90 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
retinoblastoma binding protein 4
chr1_+_153606513 56.81 ENST00000368694.3
chromatin target of PRMT1
chr8_+_125486939 56.40 ENST00000303545.3
ring finger protein 139
chr2_+_242255275 56.36 ENST00000391971.2
septin 2
chr12_+_96252706 56.17 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chrX_+_154444643 56.08 ENST00000286428.5
von Hippel-Lindau binding protein 1
chr2_-_38978492 55.81 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
serine/arginine-rich splicing factor 7
chr5_-_133561752 55.43 ENST00000519718.1
ENST00000481195.1
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr12_+_56211703 55.40 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
ORM1-like 2 (S. cerevisiae)
chr13_+_37574678 55.25 ENST00000389704.3
exosome component 8
chr7_+_73097890 55.15 ENST00000265758.2
ENST00000423166.2
ENST00000423497.1
Williams Beuren syndrome chromosome region 22
chr2_-_150444300 54.69 ENST00000303319.5
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr17_-_40169659 54.66 ENST00000457167.4
DnaJ (Hsp40) homolog, subfamily C, member 7
chr1_+_155178518 54.29 ENST00000316721.4
metaxin 1
chr5_+_137514687 54.26 ENST00000394894.3
kinesin family member 20A
chr12_+_69633372 53.75 ENST00000456847.3
ENST00000266679.8
cleavage and polyadenylation specific factor 6, 68kDa
chr4_-_103746683 53.48 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr19_-_2328572 53.29 ENST00000252622.10
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_+_52856456 53.09 ENST00000296684.5
ENST00000506765.1
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr19_+_55897699 53.09 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
ribosomal protein L28
chr20_+_61569463 53.07 ENST00000266069.3
GID complex subunit 8
chr16_-_75681522 53.05 ENST00000568378.1
ENST00000568682.1
ENST00000570215.1
ENST00000319410.5
ENST00000302445.3
lysyl-tRNA synthetase
chr11_-_34937858 52.76 ENST00000278359.5
APAF1 interacting protein
chr11_-_122930121 52.74 ENST00000524552.1
heat shock 70kDa protein 8
chr2_+_86426478 52.71 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
mitochondrial ribosomal protein L35
chr6_-_8102714 52.64 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr17_-_40169429 52.47 ENST00000316603.7
ENST00000588641.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chrX_+_106871713 52.42 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
phosphoribosyl pyrophosphate synthetase 1
chr4_-_103747011 52.40 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr3_-_12705600 52.32 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
v-raf-1 murine leukemia viral oncogene homolog 1
chr15_-_59225844 52.19 ENST00000380516.2
SAFB-like, transcription modulator
chr12_+_12966250 52.10 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr11_-_122929699 51.45 ENST00000526686.1
heat shock 70kDa protein 8
chr17_-_40169161 51.37 ENST00000589586.2
ENST00000426588.3
ENST00000589576.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr11_+_74660278 51.32 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr2_+_27851863 51.10 ENST00000264718.3
ENST00000610189.1
GPN-loop GTPase 1
chr5_+_154320623 51.04 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
mitochondrial ribosomal protein L22
chr7_-_23571586 50.98 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
transformer 2 alpha homolog (Drosophila)
chr1_-_89357179 50.98 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
general transcription factor IIB
chrX_-_20284958 50.95 ENST00000379565.3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_+_197677379 50.54 ENST00000442341.1
ribosomal protein L35a
chr2_-_150444116 50.53 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr15_+_41624892 50.46 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
nucleolar and spindle associated protein 1
chr5_+_170814803 50.38 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr11_-_58343319 50.10 ENST00000395074.2
leupaxin
chr3_+_197677047 49.68 ENST00000448864.1
ribosomal protein L35a
chr2_+_27435179 49.51 ENST00000606999.1
ENST00000405489.3
all-trans retinoic acid-induced differentiation factor
chr12_-_108954933 49.39 ENST00000431469.2
ENST00000546815.1
squamous cell carcinoma antigen recognized by T cells 3
chr8_-_117768023 49.38 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chr3_+_184079492 49.33 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
polymerase (RNA) II (DNA directed) polypeptide H
chr11_-_118972575 49.27 ENST00000432443.2
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr5_+_72112470 49.26 ENST00000447967.2
ENST00000523768.1
transportin 1
chr8_-_109260897 49.22 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
eukaryotic translation initiation factor 3, subunit E
chr17_+_66509019 49.21 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr10_+_28822236 48.98 ENST00000347934.4
ENST00000354911.4
WW domain containing adaptor with coiled-coil
chr20_-_524455 48.87 ENST00000349736.5
ENST00000217244.3
casein kinase 2, alpha 1 polypeptide
chr17_+_44668035 48.71 ENST00000398238.4
ENST00000225282.8
N-ethylmaleimide-sensitive factor
chr1_+_62901968 48.68 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
ubiquitin specific peptidase 1
chr1_+_28157273 48.59 ENST00000311772.5
ENST00000236412.7
ENST00000373931.4
protein phosphatase 1, regulatory subunit 8
chr11_+_85339623 48.52 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
transmembrane protein 126B
chr12_+_69979210 48.41 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr11_-_47447767 48.26 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr12_+_6602517 48.16 ENST00000315579.5
ENST00000539714.1
non-SMC condensin I complex, subunit D2
chr17_+_30677136 47.72 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
zinc finger protein 207
chr19_-_8386238 47.72 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr10_+_120863587 47.51 ENST00000535029.1
ENST00000361432.2
ENST00000544016.1
family with sequence similarity 45, member A
chr17_-_4269768 47.46 ENST00000396981.2
ubiquitin-conjugating enzyme E2G 1
chr5_+_32585605 47.43 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1 homolog (S. cerevisiae)
chr3_+_180630444 47.36 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
fragile X mental retardation, autosomal homolog 1
chrX_-_153285251 47.35 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr12_+_69004619 47.09 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr4_+_17616253 47.08 ENST00000237380.7
mediator complex subunit 28
chr12_+_69979446 46.95 ENST00000543146.2
chaperonin containing TCP1, subunit 2 (beta)
chr17_-_5322786 46.90 ENST00000225696.4
nucleoporin 88kDa
chr2_+_242577097 46.75 ENST00000419606.1
ENST00000474739.2
ENST00000396411.3
ENST00000425239.1
ENST00000400771.3
ENST00000430617.2
autophagy related 4B, cysteine peptidase
chr1_+_111992064 46.46 ENST00000483994.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr6_-_86352642 46.37 ENST00000355238.6
synaptotagmin binding, cytoplasmic RNA interacting protein
chr2_+_232572361 46.31 ENST00000409321.1
prothymosin, alpha
chr4_-_103746924 46.31 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
ubiquitin-conjugating enzyme E2D 3
chr16_-_28857677 46.28 ENST00000313511.3
Tu translation elongation factor, mitochondrial
chr5_+_44809027 46.25 ENST00000507110.1
mitochondrial ribosomal protein S30
chr6_+_32939964 46.23 ENST00000607833.1
bromodomain containing 2
chr14_-_23504087 46.10 ENST00000493471.2
ENST00000460922.2
proteasome (prosome, macropain) subunit, beta type, 5
chr2_-_61697862 46.07 ENST00000398571.2
ubiquitin specific peptidase 34
chr14_-_23504337 46.03 ENST00000361611.6
proteasome (prosome, macropain) subunit, beta type, 5
chr1_+_33116743 45.79 ENST00000414241.3
ENST00000373493.5
retinoblastoma binding protein 4
chr7_+_156931606 45.66 ENST00000348165.5
ubiquitin protein ligase E3C
chr4_+_57302297 45.65 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr8_+_145149930 45.48 ENST00000318911.4
cytochrome c-1
chr11_+_47600562 45.38 ENST00000263774.4
ENST00000529276.1
ENST00000528192.1
ENST00000530295.1
ENST00000534208.1
ENST00000534716.2
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
chr7_+_148395959 45.17 ENST00000325222.4
cullin 1
chr1_-_153949751 45.13 ENST00000428469.1
jumping translocation breakpoint
chr19_+_17378278 44.92 ENST00000596335.1
ENST00000601436.1
ENST00000595632.1
BRISC and BRCA1 A complex member 1
chrX_-_53461288 44.83 ENST00000375298.4
ENST00000375304.5
hydroxysteroid (17-beta) dehydrogenase 10
chr10_-_120938303 44.71 ENST00000356951.3
ENST00000298510.2
peroxiredoxin 3
chr18_+_9102592 44.65 ENST00000318388.6
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr17_-_4269920 44.62 ENST00000572484.1
ubiquitin-conjugating enzyme E2G 1
chr19_+_17378159 44.60 ENST00000598188.1
ENST00000359435.4
ENST00000599474.1
ENST00000599057.1
ENST00000601043.1
ENST00000447614.2
BRISC and BRCA1 A complex member 1
chr12_-_54070098 44.42 ENST00000394349.3
ENST00000549164.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr8_-_67974552 44.42 ENST00000357849.4
COP9 signalosome subunit 5
chrX_+_153991025 44.34 ENST00000369550.5
dyskeratosis congenita 1, dyskerin
chr14_-_23398565 44.20 ENST00000397440.4
ENST00000538452.1
ENST00000421938.2
ENST00000554867.1
ENST00000556616.1
ENST00000216350.8
ENST00000553550.1
ENST00000397441.2
ENST00000553897.1
protein arginine methyltransferase 5
chrX_+_123094672 44.15 ENST00000354548.5
ENST00000458700.1
stromal antigen 2
chr7_+_135242652 44.09 ENST00000285968.6
ENST00000440390.2
nucleoporin 205kDa
chr17_+_65713925 44.07 ENST00000253247.4
nucleolar protein 11
chr4_-_174256276 44.05 ENST00000296503.5
high mobility group box 2
chr12_-_54069856 44.02 ENST00000602871.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr1_-_161087802 43.92 ENST00000368010.3
prefoldin subunit 2
chr14_+_51706886 43.82 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr2_+_27434860 43.73 ENST00000380171.3
all-trans retinoic acid-induced differentiation factor
chr3_+_180630090 43.72 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr2_-_230786679 43.69 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
thyroid hormone receptor interactor 12
chrX_+_24072833 43.69 ENST00000253039.4
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_161284047 43.65 ENST00000367975.2
ENST00000342751.4
ENST00000432287.2
ENST00000392169.2
ENST00000513009.1
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr10_+_75936444 43.64 ENST00000372734.3
ENST00000541550.1
adenosine kinase
chrX_-_118986911 43.61 ENST00000276201.2
ENST00000345865.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr1_-_153950164 43.51 ENST00000271843.4
jumping translocation breakpoint
chr14_-_102605983 43.51 ENST00000334701.7
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr22_+_21921994 43.49 ENST00000545681.1
ubiquitin-conjugating enzyme E2L 3
chr2_-_174828892 43.42 ENST00000418194.2
Sp3 transcription factor
chr2_+_242255297 43.37 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
septin 2
chr5_-_137514288 43.36 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
bromodomain containing 8
chr14_-_23504432 43.18 ENST00000425762.2
proteasome (prosome, macropain) subunit, beta type, 5
chr1_-_153950098 42.99 ENST00000356648.1
jumping translocation breakpoint
chr11_-_73687997 42.75 ENST00000545212.1
uncoupling protein 2 (mitochondrial, proton carrier)

Network of associatons between targets according to the STRING database.

First level regulatory network of TAF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
44.7 44.7 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
34.1 102.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
31.8 95.4 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
29.1 116.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
27.2 81.6 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
27.0 80.9 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
26.8 80.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
26.6 79.8 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
26.3 183.9 GO:0033484 nitric oxide homeostasis(GO:0033484)
26.1 78.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
25.6 76.8 GO:0044209 AMP salvage(GO:0044209)
24.4 24.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
23.7 142.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
23.6 94.5 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
23.4 117.0 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
23.2 69.7 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
22.7 68.2 GO:0097212 lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
22.6 181.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
22.6 67.8 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
22.5 180.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
22.2 133.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
22.1 66.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
21.5 64.5 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
21.1 147.9 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
20.2 221.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
19.7 98.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
19.0 76.0 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
18.7 187.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
18.6 55.9 GO:0051697 protein delipidation(GO:0051697)
18.2 90.9 GO:0006167 AMP biosynthetic process(GO:0006167)
17.7 53.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
17.6 70.2 GO:0006382 adenosine to inosine editing(GO:0006382)
17.0 51.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
16.8 151.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
16.4 98.2 GO:0071046 nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
16.1 161.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
15.9 111.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
15.4 46.2 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
15.3 183.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
15.3 259.7 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
15.1 15.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
14.7 58.8 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
14.6 29.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
14.6 87.6 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
14.6 87.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
14.4 57.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
14.2 99.7 GO:1902416 positive regulation of mRNA binding(GO:1902416)
14.2 71.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
14.1 197.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
14.0 41.9 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
13.6 27.1 GO:1903376 neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
13.2 211.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
12.9 90.5 GO:0070269 pyroptosis(GO:0070269)
12.9 939.0 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
12.7 89.2 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
12.7 51.0 GO:1904798 positive regulation of core promoter binding(GO:1904798)
12.7 50.9 GO:0043555 regulation of translation in response to stress(GO:0043555)
12.7 76.1 GO:0043144 snoRNA processing(GO:0043144)
12.7 88.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
12.5 87.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
12.2 73.1 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
12.2 12.2 GO:0097695 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
12.1 193.4 GO:0043248 proteasome assembly(GO:0043248)
11.9 35.6 GO:0061198 fungiform papilla formation(GO:0061198)
11.8 23.5 GO:1902415 regulation of mRNA binding(GO:1902415)
11.6 46.5 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
11.5 92.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
11.3 33.9 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
11.2 347.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
11.2 156.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
11.1 66.7 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
11.0 44.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
11.0 11.0 GO:0040031 snRNA modification(GO:0040031)
10.9 54.4 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
10.9 43.5 GO:0043335 protein unfolding(GO:0043335)
10.8 54.2 GO:0019348 dolichol metabolic process(GO:0019348)
10.8 54.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
10.8 75.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
10.7 32.0 GO:0046294 formaldehyde catabolic process(GO:0046294)
10.2 30.7 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
10.2 40.8 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
10.1 161.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
10.0 79.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
9.8 68.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
9.7 48.6 GO:0006999 nuclear pore organization(GO:0006999)
9.3 149.3 GO:0000338 protein deneddylation(GO:0000338)
9.3 55.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
9.2 73.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
9.0 582.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
8.9 133.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
8.8 26.5 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
8.8 35.2 GO:0002192 IRES-dependent translational initiation(GO:0002192)
8.3 16.6 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
8.0 79.6 GO:0010265 SCF complex assembly(GO:0010265)
8.0 15.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
7.8 78.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
7.8 54.5 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
7.8 15.5 GO:0034227 tRNA thio-modification(GO:0034227)
7.7 31.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
7.7 30.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
7.6 53.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
7.6 15.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
7.6 75.6 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
7.6 22.7 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
7.5 30.2 GO:0001845 phagolysosome assembly(GO:0001845)
7.5 60.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
7.4 22.3 GO:0070541 response to platinum ion(GO:0070541)
7.4 37.1 GO:0035617 stress granule disassembly(GO:0035617)
7.3 58.8 GO:0070475 rRNA base methylation(GO:0070475)
7.2 50.4 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
7.2 151.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
7.0 20.9 GO:0051685 maintenance of ER location(GO:0051685)
6.9 27.5 GO:0007538 primary sex determination(GO:0007538)
6.8 41.0 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
6.8 67.8 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
6.7 33.5 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
6.6 91.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
6.5 51.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
6.4 89.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
6.4 19.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
6.2 18.7 GO:0090234 regulation of kinetochore assembly(GO:0090234)
6.2 80.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
6.2 37.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
6.2 18.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
6.1 55.1 GO:0071763 nuclear membrane organization(GO:0071763)
6.1 159.0 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
6.1 30.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
6.0 18.0 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
6.0 6.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
5.9 70.6 GO:0018206 peptidyl-methionine modification(GO:0018206)
5.8 151.3 GO:0006337 nucleosome disassembly(GO:0006337)
5.7 137.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
5.7 22.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
5.7 51.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
5.7 34.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
5.6 16.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
5.6 67.7 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
5.6 16.7 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
5.6 88.9 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
5.5 27.7 GO:1900063 regulation of peroxisome organization(GO:1900063)
5.5 16.6 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
5.5 93.8 GO:0046931 pore complex assembly(GO:0046931)
5.4 21.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
5.4 43.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
5.4 21.6 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
5.4 21.5 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
5.3 5.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
5.3 154.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
5.3 117.1 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
5.3 5.3 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
5.3 36.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
5.2 20.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
5.0 231.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
5.0 40.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
5.0 24.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
4.9 93.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
4.9 29.2 GO:0051661 maintenance of centrosome location(GO:0051661)
4.8 38.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
4.8 38.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
4.8 48.3 GO:0015939 pantothenate metabolic process(GO:0015939)
4.8 14.4 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
4.7 18.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
4.7 14.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
4.7 23.3 GO:0002084 protein depalmitoylation(GO:0002084)
4.7 139.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
4.6 9.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
4.5 27.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
4.4 128.1 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
4.4 48.5 GO:0006621 protein retention in ER lumen(GO:0006621)
4.4 17.6 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
4.4 65.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
4.3 73.0 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
4.3 42.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
4.3 123.9 GO:0043968 histone H2A acetylation(GO:0043968)
4.2 227.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
4.2 29.3 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
4.2 138.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
4.2 12.5 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
4.1 32.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
4.1 16.2 GO:0048496 maintenance of organ identity(GO:0048496)
4.1 32.5 GO:0009838 abscission(GO:0009838)
4.0 71.8 GO:0007021 tubulin complex assembly(GO:0007021)
4.0 27.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
4.0 63.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
4.0 115.2 GO:0006491 N-glycan processing(GO:0006491)
3.9 47.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
3.9 27.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
3.9 11.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
3.9 3.9 GO:0090316 positive regulation of intracellular protein transport(GO:0090316)
3.9 31.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
3.9 100.8 GO:0009235 cobalamin metabolic process(GO:0009235)
3.8 3.8 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
3.8 38.0 GO:0051383 kinetochore organization(GO:0051383)
3.8 34.0 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
3.7 15.0 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
3.7 33.7 GO:1901977 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
3.7 11.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
3.7 265.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
3.6 7.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
3.6 10.9 GO:0015680 intracellular copper ion transport(GO:0015680)
3.6 54.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
3.6 32.5 GO:0042255 ribosome assembly(GO:0042255)
3.6 10.8 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
3.6 46.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
3.5 74.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
3.5 3.5 GO:0060767 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
3.5 20.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
3.4 10.3 GO:0006333 chromatin assembly or disassembly(GO:0006333)
3.4 20.7 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
3.4 30.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
3.4 41.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
3.4 87.8 GO:0030033 microvillus assembly(GO:0030033)
3.4 13.5 GO:0071233 cellular response to leucine(GO:0071233)
3.4 507.3 GO:0045047 protein targeting to ER(GO:0045047)
3.3 13.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
3.3 78.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
3.3 35.8 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
3.3 6.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
3.2 22.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
3.2 12.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
3.1 75.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
3.1 40.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
3.0 6.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
3.0 11.8 GO:0034398 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
2.9 26.4 GO:0031053 primary miRNA processing(GO:0031053)
2.9 174.8 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
2.9 8.7 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
2.8 42.3 GO:0006449 regulation of translational termination(GO:0006449)
2.8 181.2 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
2.8 52.9 GO:0030488 tRNA methylation(GO:0030488)
2.8 11.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
2.7 27.2 GO:1904424 regulation of GTP binding(GO:1904424)
2.7 43.6 GO:0072321 chaperone-mediated protein transport(GO:0072321)
2.7 10.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
2.7 21.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
2.7 8.0 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
2.7 8.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
2.7 42.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
2.7 21.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
2.6 39.7 GO:0000154 rRNA modification(GO:0000154)
2.6 89.1 GO:0045841 negative regulation of mitotic metaphase/anaphase transition(GO:0045841) mitotic spindle checkpoint(GO:0071174) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100)
2.6 7.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
2.6 28.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
2.6 7.8 GO:0018201 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
2.6 23.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
2.6 141.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
2.6 12.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
2.5 20.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
2.5 15.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
2.5 32.6 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
2.4 24.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
2.4 16.8 GO:0001675 acrosome assembly(GO:0001675)
2.4 18.9 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
2.4 11.8 GO:0046203 spermidine catabolic process(GO:0046203)
2.3 48.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
2.3 6.9 GO:0006970 response to osmotic stress(GO:0006970)
2.3 59.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.3 9.1 GO:0030242 pexophagy(GO:0030242)
2.3 11.4 GO:0016240 autophagosome docking(GO:0016240)
2.3 15.9 GO:0060576 intestinal epithelial cell development(GO:0060576)
2.3 13.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
2.2 11.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
2.2 108.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
2.2 454.4 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
2.1 15.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
2.1 6.4 GO:0065001 specification of axis polarity(GO:0065001) negative regulation of tooth mineralization(GO:0070171)
2.1 258.6 GO:0008380 RNA splicing(GO:0008380)
2.1 25.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
2.1 12.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.1 12.5 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.1 56.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
2.0 20.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
2.0 8.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
2.0 18.3 GO:0042182 ketone catabolic process(GO:0042182)
2.0 8.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.0 20.0 GO:0006105 succinate metabolic process(GO:0006105)
2.0 21.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
2.0 11.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
1.9 7.8 GO:0090235 regulation of metaphase plate congression(GO:0090235)
1.9 7.5 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.8 16.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.8 16.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
1.8 5.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.8 51.0 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
1.8 17.8 GO:0044458 motile cilium assembly(GO:0044458)
1.8 5.3 GO:0072553 terminal button organization(GO:0072553)
1.7 8.7 GO:0022615 protein to membrane docking(GO:0022615)
1.7 17.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.7 13.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
1.7 5.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.7 18.2 GO:0031935 regulation of chromatin silencing(GO:0031935)
1.7 18.2 GO:0015886 heme transport(GO:0015886)
1.7 5.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.6 44.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
1.6 27.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.6 12.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
1.6 46.6 GO:0006378 mRNA polyadenylation(GO:0006378)
1.6 110.3 GO:0045454 cell redox homeostasis(GO:0045454)
1.6 7.9 GO:0070987 error-free translesion synthesis(GO:0070987)
1.6 37.8 GO:0000060 protein import into nucleus, translocation(GO:0000060)
1.6 22.0 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
1.6 57.9 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
1.6 6.2 GO:0070459 prolactin secretion(GO:0070459)
1.5 26.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.5 21.6 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
1.5 29.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
1.5 7.6 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
1.5 42.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
1.5 15.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
1.5 130.7 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
1.5 3.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
1.5 212.5 GO:0000910 cytokinesis(GO:0000910)
1.4 14.5 GO:0051451 myoblast migration(GO:0051451)
1.4 52.2 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
1.4 61.8 GO:0043488 regulation of mRNA stability(GO:0043488)
1.4 50.8 GO:0090382 phagosome maturation(GO:0090382)
1.4 15.5 GO:0045008 depyrimidination(GO:0045008)
1.4 4.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
1.4 18.0 GO:0044804 nucleophagy(GO:0044804)
1.4 16.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.4 2.7 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
1.3 2.6 GO:0060789 hair follicle placode formation(GO:0060789)
1.3 8.9 GO:0006264 mitochondrial DNA replication(GO:0006264)
1.2 2.5 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
1.2 8.7 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
1.2 22.4 GO:0006817 phosphate ion transport(GO:0006817)
1.2 10.4 GO:0042659 regulation of cell fate specification(GO:0042659)
1.1 25.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
1.1 5.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.1 21.1 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
1.1 8.9 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
1.1 3.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.1 6.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.1 20.1 GO:0006261 DNA-dependent DNA replication(GO:0006261)
1.1 59.9 GO:0006413 translational initiation(GO:0006413)
1.0 37.4 GO:0014003 oligodendrocyte development(GO:0014003)
1.0 15.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
1.0 2.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.0 44.3 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.0 6.1 GO:0016584 nucleosome positioning(GO:0016584)
1.0 21.2 GO:1901998 toxin transport(GO:1901998)
1.0 79.5 GO:0070527 platelet aggregation(GO:0070527)
1.0 6.0 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
1.0 6.9 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
1.0 3.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.0 11.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.0 14.5 GO:0001881 receptor recycling(GO:0001881)
1.0 3.8 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
1.0 10.5 GO:0045116 protein neddylation(GO:0045116)
1.0 10.5 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.9 36.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.9 2.8 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.9 2.8 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.9 11.1 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.9 38.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.9 9.1 GO:0034453 microtubule anchoring(GO:0034453)
0.9 10.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.9 10.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.9 3.5 GO:0030901 midbrain development(GO:0030901)
0.9 32.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.9 12.9 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.8 3.3 GO:0071352 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
0.8 13.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.8 4.8 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.8 1.6 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.8 12.7 GO:0002643 regulation of tolerance induction(GO:0002643)
0.8 42.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.8 15.0 GO:0007020 microtubule nucleation(GO:0007020)
0.8 13.4 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.8 7.1 GO:0007097 nuclear migration(GO:0007097)
0.8 12.5 GO:0009650 UV protection(GO:0009650)
0.8 8.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.8 46.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.8 22.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.7 3.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.7 5.2 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.7 8.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.7 2.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.7 33.9 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.7 2.8 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092) negative regulation of glycogen metabolic process(GO:0070874)
0.7 13.2 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.7 10.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.7 22.3 GO:0032508 DNA duplex unwinding(GO:0032508)
0.7 21.4 GO:0017145 stem cell division(GO:0017145)
0.7 33.4 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.6 13.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.6 14.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.6 92.7 GO:0006457 protein folding(GO:0006457)
0.6 6.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.6 7.3 GO:0009303 rRNA transcription(GO:0009303)
0.6 12.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.6 10.6 GO:0006903 vesicle targeting(GO:0006903)
0.6 12.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.6 90.6 GO:0008360 regulation of cell shape(GO:0008360)
0.6 5.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.6 8.6 GO:2000147 positive regulation of cell migration(GO:0030335) positive regulation of locomotion(GO:0040017) positive regulation of cellular component movement(GO:0051272) positive regulation of cell motility(GO:2000147)
0.5 10.0 GO:0006012 galactose metabolic process(GO:0006012)
0.5 5.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.5 38.0 GO:0045727 positive regulation of translation(GO:0045727)
0.5 6.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 29.5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.5 5.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.5 2.0 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.5 14.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.5 20.1 GO:0006611 protein export from nucleus(GO:0006611)
0.5 0.5 GO:0061035 regulation of cartilage development(GO:0061035)
0.5 15.7 GO:0051603 proteolysis involved in cellular protein catabolic process(GO:0051603)
0.5 12.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.5 12.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 1.4 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.4 3.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.4 40.3 GO:0045471 response to ethanol(GO:0045471)
0.4 13.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.4 11.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.4 5.8 GO:0021697 cell differentiation in hindbrain(GO:0021533) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar cortex formation(GO:0021697) cerebellar Purkinje cell differentiation(GO:0021702)
0.4 2.0 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.4 7.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.4 5.9 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 24.5 GO:0001909 leukocyte mediated cytotoxicity(GO:0001909)
0.3 25.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.3 8.3 GO:0070207 protein homotrimerization(GO:0070207)
0.3 12.5 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.3 7.4 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.3 16.4 GO:0006968 cellular defense response(GO:0006968)
0.2 0.7 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.2 7.0 GO:0007566 embryo implantation(GO:0007566)
0.2 4.4 GO:0002076 osteoblast development(GO:0002076)
0.2 8.5 GO:0006397 mRNA processing(GO:0006397)
0.2 2.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 10.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.9 GO:0071545 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) inositol phosphate catabolic process(GO:0071545) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 4.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 12.6 GO:0048675 axon extension(GO:0048675)
0.2 2.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.2 1.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.2 3.9 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 0.5 GO:0072205 metanephric collecting duct development(GO:0072205)
0.2 4.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.7 GO:0044728 DNA methylation or demethylation(GO:0044728)
0.1 1.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 4.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 13.7 GO:0060348 bone development(GO:0060348)
0.1 1.2 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.5 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.3 GO:0035601 protein deacylation(GO:0035601)
0.1 3.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.6 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 1.7 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 1.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.6 GO:0015825 L-serine transport(GO:0015825)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 1.0 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
0.0 1.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 4.1 GO:0042113 B cell activation(GO:0042113)
0.0 0.7 GO:0090398 cellular senescence(GO:0090398)
0.0 0.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.4 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 1.0 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.4 GO:0022900 electron transport chain(GO:0022900)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
37.8 302.1 GO:0042382 paraspeckles(GO:0042382)
32.0 128.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
30.4 30.4 GO:0031372 UBC13-MMS2 complex(GO:0031372)
26.9 188.1 GO:0016589 NURF complex(GO:0016589)
25.4 177.8 GO:0046581 intercellular canaliculus(GO:0046581)
22.9 68.8 GO:0034455 t-UTP complex(GO:0034455)
22.5 112.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
21.8 87.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
21.7 151.9 GO:0016272 prefoldin complex(GO:0016272)
21.5 86.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
20.0 541.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
19.5 214.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
19.2 57.5 GO:0032302 MutSbeta complex(GO:0032302)
19.1 76.5 GO:0071001 U4/U6 snRNP(GO:0071001)
18.1 181.0 GO:0000796 condensin complex(GO:0000796)
17.8 88.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
16.7 117.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
15.7 283.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
15.7 78.6 GO:0044530 supraspliceosomal complex(GO:0044530)
15.7 156.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
15.5 62.2 GO:0000798 nuclear cohesin complex(GO:0000798)
15.2 242.8 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
14.6 43.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
14.5 43.6 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
14.2 99.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
14.1 42.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
14.0 41.9 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
13.8 55.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
13.4 134.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
13.0 38.9 GO:0070557 PCNA-p21 complex(GO:0070557)
12.6 189.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
12.6 126.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
12.5 62.6 GO:0035061 interchromatin granule(GO:0035061)
12.4 62.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
12.2 134.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
12.2 36.6 GO:1990246 uniplex complex(GO:1990246)
11.9 35.8 GO:0005873 plus-end kinesin complex(GO:0005873)
11.7 93.3 GO:0070552 BRISC complex(GO:0070552)
11.7 116.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
11.4 34.2 GO:0071159 NF-kappaB complex(GO:0071159)
11.3 170.2 GO:0000346 transcription export complex(GO:0000346)
11.3 124.3 GO:0031595 nuclear proteasome complex(GO:0031595)
11.2 235.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
11.2 55.8 GO:0034457 Mpp10 complex(GO:0034457)
10.9 32.6 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
10.8 270.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
10.7 193.3 GO:0034709 methylosome(GO:0034709)
10.6 74.4 GO:0061700 GATOR2 complex(GO:0061700)
10.5 52.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
10.4 72.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
10.0 129.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
9.8 39.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
9.7 58.0 GO:0030905 retromer, tubulation complex(GO:0030905)
9.6 48.0 GO:0070470 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
9.3 74.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
9.2 138.0 GO:0008290 F-actin capping protein complex(GO:0008290)
9.1 91.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
9.0 27.1 GO:0005826 actomyosin contractile ring(GO:0005826) GID complex(GO:0034657)
8.9 35.4 GO:0044611 nuclear pore inner ring(GO:0044611)
8.8 123.1 GO:0097227 sperm annulus(GO:0097227)
8.5 521.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
8.5 67.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
8.2 40.8 GO:0000444 MIS12/MIND type complex(GO:0000444)
8.0 192.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
8.0 55.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
7.9 165.5 GO:0000812 Swr1 complex(GO:0000812)
7.4 44.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
7.1 50.0 GO:0005787 signal peptidase complex(GO:0005787)
6.8 20.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
6.6 79.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
6.5 91.6 GO:0042405 nuclear inclusion body(GO:0042405)
6.5 267.3 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
6.4 45.0 GO:0031415 NatA complex(GO:0031415)
6.3 25.1 GO:0005797 Golgi medial cisterna(GO:0005797)
6.2 67.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
6.1 61.4 GO:0090543 Flemming body(GO:0090543)
6.1 152.4 GO:0035145 exon-exon junction complex(GO:0035145)
6.0 102.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
6.0 6.0 GO:0071203 WASH complex(GO:0071203)
5.9 17.8 GO:0044393 microspike(GO:0044393)
5.9 23.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
5.8 23.1 GO:0089701 U2AF(GO:0089701)
5.6 128.3 GO:0071141 SMAD protein complex(GO:0071141)
5.4 16.2 GO:1903349 omegasome membrane(GO:1903349)
5.4 16.1 GO:0070939 Dsl1p complex(GO:0070939)
5.3 37.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
5.2 10.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
5.2 67.7 GO:0097433 dense body(GO:0097433)
5.2 20.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
5.1 56.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
5.1 56.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
5.1 40.5 GO:0097208 alveolar lamellar body(GO:0097208)
5.0 50.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
4.9 64.3 GO:0042555 MCM complex(GO:0042555)
4.8 14.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
4.7 28.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
4.7 75.0 GO:0000178 exosome (RNase complex)(GO:0000178)
4.6 64.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
4.5 17.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
4.4 13.2 GO:0001740 Barr body(GO:0001740)
4.3 12.8 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
4.3 55.5 GO:0008385 IkappaB kinase complex(GO:0008385)
4.3 93.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
4.2 21.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
4.2 12.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
4.1 32.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
4.1 12.2 GO:0072487 MSL complex(GO:0072487)
4.1 20.3 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
4.0 68.2 GO:0031616 spindle pole centrosome(GO:0031616)
4.0 40.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
4.0 431.0 GO:0015934 large ribosomal subunit(GO:0015934)
3.9 89.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
3.8 60.7 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
3.8 22.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
3.7 52.5 GO:0017119 Golgi transport complex(GO:0017119)
3.7 242.6 GO:0005637 nuclear inner membrane(GO:0005637)
3.6 14.2 GO:0030686 90S preribosome(GO:0030686)
3.5 108.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
3.5 17.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
3.5 27.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
3.4 17.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
3.4 34.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
3.4 91.8 GO:0032040 small-subunit processome(GO:0032040)
3.3 157.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
3.3 20.0 GO:0032039 integrator complex(GO:0032039)
3.3 39.8 GO:0005686 U2 snRNP(GO:0005686)
3.3 56.1 GO:0010369 chromocenter(GO:0010369)
3.2 38.8 GO:0030008 TRAPP complex(GO:0030008)
3.2 76.8 GO:0030137 COPI-coated vesicle(GO:0030137)
3.2 171.5 GO:0000502 proteasome complex(GO:0000502)
3.2 19.1 GO:0051286 cell tip(GO:0051286)
3.1 28.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
3.0 24.4 GO:0072546 ER membrane protein complex(GO:0072546)
3.0 304.6 GO:0005840 ribosome(GO:0005840)
3.0 24.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
3.0 18.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
3.0 59.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
2.8 120.6 GO:0008180 COP9 signalosome(GO:0008180)
2.8 52.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
2.7 144.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
2.7 18.7 GO:0070187 telosome(GO:0070187)
2.6 49.9 GO:0001891 phagocytic cup(GO:0001891)
2.6 33.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
2.6 138.6 GO:0005871 kinesin complex(GO:0005871)
2.5 15.0 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
2.5 61.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
2.4 59.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
2.4 356.7 GO:0005681 spliceosomal complex(GO:0005681)
2.3 25.7 GO:0042575 DNA polymerase complex(GO:0042575)
2.3 4.6 GO:0000974 Prp19 complex(GO:0000974)
2.3 11.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.2 8.7 GO:0032021 NELF complex(GO:0032021)
2.1 34.1 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
2.1 53.7 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
2.0 18.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.0 57.3 GO:0031143 pseudopodium(GO:0031143)
2.0 158.5 GO:0005811 lipid particle(GO:0005811)
2.0 8.1 GO:0032044 DSIF complex(GO:0032044)
1.9 79.7 GO:0002102 podosome(GO:0002102)
1.9 32.1 GO:0030904 retromer complex(GO:0030904)
1.9 63.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.9 5.6 GO:1990423 RZZ complex(GO:1990423)
1.9 35.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.8 11.0 GO:0000322 storage vacuole(GO:0000322)
1.8 91.1 GO:0043034 costamere(GO:0043034)
1.8 19.7 GO:0035631 CD40 receptor complex(GO:0035631)
1.7 60.7 GO:0016592 mediator complex(GO:0016592)
1.7 5.1 GO:0018444 translation release factor complex(GO:0018444)
1.7 15.0 GO:0005827 polar microtubule(GO:0005827)
1.6 4.8 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
1.6 43.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
1.5 3.0 GO:0031213 RSF complex(GO:0031213)
1.5 42.3 GO:1904115 axon cytoplasm(GO:1904115)
1.5 7.5 GO:0044327 dendritic spine head(GO:0044327)
1.5 4.4 GO:0035976 AP1 complex(GO:0035976)
1.4 40.0 GO:0005719 nuclear euchromatin(GO:0005719)
1.4 44.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
1.4 2.7 GO:0001940 male pronucleus(GO:0001940)
1.3 47.2 GO:0005876 spindle microtubule(GO:0005876)
1.3 1.3 GO:0000806 Y chromosome(GO:0000806)
1.3 12.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.2 13.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.2 35.7 GO:0005680 anaphase-promoting complex(GO:0005680)
1.2 7.3 GO:0030014 CCR4-NOT complex(GO:0030014)
1.2 8.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
1.2 74.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.1 20.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.1 10.3 GO:0005869 dynactin complex(GO:0005869)
1.1 68.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
1.1 31.9 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
1.1 54.9 GO:0005801 cis-Golgi network(GO:0005801)
1.1 18.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
1.0 8.2 GO:0005641 nuclear envelope lumen(GO:0005641)
1.0 3.0 GO:0005879 axonemal microtubule(GO:0005879)
1.0 66.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
1.0 81.1 GO:0035578 azurophil granule lumen(GO:0035578)
1.0 9.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.9 50.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.9 20.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.9 7.0 GO:0005642 annulate lamellae(GO:0005642)
0.9 6.9 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.9 19.6 GO:0071564 npBAF complex(GO:0071564)
0.8 202.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.8 109.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.8 26.6 GO:0030125 clathrin vesicle coat(GO:0030125)
0.8 34.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.8 3.2 GO:0030314 junctional membrane complex(GO:0030314)
0.8 318.7 GO:0005635 nuclear envelope(GO:0005635)
0.8 3.1 GO:0044194 cytolytic granule(GO:0044194)
0.8 6.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.7 57.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.7 3.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.7 7.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.7 17.0 GO:0000421 autophagosome membrane(GO:0000421)
0.7 51.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.7 4.0 GO:0001520 outer dense fiber(GO:0001520)
0.6 31.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.6 41.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.6 6.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.6 68.0 GO:0005795 Golgi stack(GO:0005795)
0.6 19.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.6 12.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.6 1.7 GO:0061574 ASAP complex(GO:0061574)
0.6 2.2 GO:0043259 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.5 12.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 8.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.5 105.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.5 2.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 141.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.4 16.3 GO:0045095 keratin filament(GO:0045095)
0.4 2.7 GO:0070382 synaptic vesicle(GO:0008021) exocytic vesicle(GO:0070382)
0.4 5.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 6.0 GO:0044295 axonal growth cone(GO:0044295)
0.3 31.6 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.3 14.7 GO:0031526 brush border membrane(GO:0031526)
0.3 79.7 GO:0016607 nuclear speck(GO:0016607)
0.2 6.6 GO:0042581 specific granule(GO:0042581)
0.2 20.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.2 10.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 7.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.2 14.9 GO:0031968 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.2 17.4 GO:0031091 platelet alpha granule(GO:0031091)
0.2 11.6 GO:0030496 midbody(GO:0030496)
0.2 12.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 25.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 105.9 GO:0005615 extracellular space(GO:0005615)
0.1 7.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 11.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 9.5 GO:0072562 blood microparticle(GO:0072562)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 3.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 173.6 GO:0070062 extracellular exosome(GO:0070062)
0.1 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 12.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
32.0 128.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
29.1 116.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
23.2 69.7 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
22.3 89.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
21.5 86.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
20.5 102.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
20.0 140.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
19.5 78.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
19.3 96.4 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
19.1 57.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
18.5 184.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
18.0 108.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
17.7 71.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
17.5 87.6 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
17.4 121.7 GO:0050733 RS domain binding(GO:0050733)
17.2 34.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
16.4 49.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
16.4 98.4 GO:0035500 MH2 domain binding(GO:0035500)
16.0 64.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
15.7 110.2 GO:0030621 U4 snRNA binding(GO:0030621)
15.7 47.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
15.6 46.9 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
15.4 46.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
15.2 45.5 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
14.8 74.1 GO:0070404 NADH binding(GO:0070404)
14.7 117.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
13.9 125.5 GO:0033592 RNA strand annealing activity(GO:0033592)
13.6 40.9 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
13.5 40.4 GO:0005047 signal recognition particle binding(GO:0005047)
13.2 39.7 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
13.0 181.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
12.7 88.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
12.7 50.6 GO:0005046 KDEL sequence binding(GO:0005046)
12.6 37.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
11.7 35.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
11.7 58.3 GO:1990460 leptin receptor binding(GO:1990460)
11.3 124.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
11.0 44.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
11.0 296.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
10.7 32.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
10.6 117.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
10.6 52.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
10.5 555.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
9.9 69.5 GO:0050815 phosphoserine binding(GO:0050815)
9.3 37.3 GO:0099609 microtubule lateral binding(GO:0099609)
9.3 37.1 GO:0036033 mediator complex binding(GO:0036033)
9.2 184.6 GO:0070717 poly-purine tract binding(GO:0070717)
9.2 36.8 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
9.0 35.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
8.8 265.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
8.6 34.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
8.5 221.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
8.5 194.9 GO:0008327 methyl-CpG binding(GO:0008327)
8.5 33.9 GO:0004594 pantothenate kinase activity(GO:0004594)
8.2 24.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
8.1 48.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
7.9 79.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
7.7 30.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
7.5 29.9 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
7.4 44.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
7.1 21.2 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
7.1 63.6 GO:0030911 TPR domain binding(GO:0030911)
7.0 55.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
7.0 41.9 GO:0042296 ISG15 transferase activity(GO:0042296)
7.0 97.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
6.9 20.8 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
6.9 20.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
6.8 47.6 GO:0008312 7S RNA binding(GO:0008312)
6.8 81.6 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
6.6 231.6 GO:0051059 NF-kappaB binding(GO:0051059)
6.6 98.3 GO:0042809 vitamin D receptor binding(GO:0042809)
6.4 32.0 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
6.4 38.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
6.3 269.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
6.1 220.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
6.1 67.3 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
6.1 42.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
6.1 48.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
6.0 72.3 GO:0017070 U6 snRNA binding(GO:0017070)
6.0 18.0 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
6.0 381.6 GO:0003743 translation initiation factor activity(GO:0003743)
5.9 23.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
5.8 29.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
5.8 23.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
5.8 17.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
5.6 44.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
5.5 33.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
5.4 70.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
5.4 248.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
5.4 171.4 GO:0001671 ATPase activator activity(GO:0001671)
5.2 36.4 GO:0042979 ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979)
5.1 56.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
5.1 66.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
5.1 40.7 GO:0004111 creatine kinase activity(GO:0004111)
5.1 35.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
5.1 50.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
5.0 20.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
5.0 24.9 GO:0030348 syntaxin-3 binding(GO:0030348)
4.9 1068.8 GO:0003735 structural constituent of ribosome(GO:0003735)
4.8 38.4 GO:0016842 amidine-lyase activity(GO:0016842)
4.6 23.0 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
4.6 45.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
4.5 76.8 GO:0019206 nucleoside kinase activity(GO:0019206)
4.2 12.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
4.2 87.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
4.2 58.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
4.1 289.4 GO:0019003 GDP binding(GO:0019003)
3.9 11.8 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
3.9 43.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
3.9 85.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
3.8 130.5 GO:0043022 ribosome binding(GO:0043022)
3.8 99.7 GO:0036002 pre-mRNA binding(GO:0036002)
3.8 57.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
3.7 11.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
3.7 117.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
3.6 32.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
3.6 14.4 GO:0097001 ceramide binding(GO:0097001)
3.6 50.4 GO:0016018 cyclosporin A binding(GO:0016018)
3.6 10.8 GO:0032090 Pyrin domain binding(GO:0032090)
3.4 10.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
3.4 116.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
3.3 33.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
3.3 29.5 GO:0015288 porin activity(GO:0015288)
3.2 12.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
3.2 25.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
3.2 35.0 GO:0000150 recombinase activity(GO:0000150)
3.2 149.4 GO:0051879 Hsp90 protein binding(GO:0051879)
3.2 120.3 GO:0004532 exoribonuclease activity(GO:0004532)
3.1 12.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
3.0 18.0 GO:0019776 Atg8 ligase activity(GO:0019776)
3.0 20.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
3.0 77.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.9 88.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
2.9 23.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
2.9 26.1 GO:0070182 DNA polymerase binding(GO:0070182)
2.8 58.4 GO:0050811 GABA receptor binding(GO:0050811)
2.8 16.6 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
2.8 16.6 GO:0017018 myosin phosphatase activity(GO:0017018)
2.7 10.9 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
2.7 8.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
2.7 32.4 GO:0003678 DNA helicase activity(GO:0003678)
2.7 13.5 GO:0070728 leucine binding(GO:0070728)
2.7 61.3 GO:0001056 RNA polymerase III activity(GO:0001056)
2.6 52.8 GO:0005537 mannose binding(GO:0005537)
2.6 183.9 GO:0005507 copper ion binding(GO:0005507)
2.6 10.5 GO:0031685 adenosine receptor binding(GO:0031685)
2.6 7.8 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
2.6 20.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
2.6 12.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
2.4 56.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
2.4 43.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
2.4 26.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
2.4 11.9 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
2.4 37.7 GO:0070628 proteasome binding(GO:0070628)
2.3 18.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
2.3 11.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
2.3 96.7 GO:0008536 Ran GTPase binding(GO:0008536)
2.3 22.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.2 11.2 GO:0031491 nucleosome binding(GO:0031491)
2.2 15.5 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
2.2 123.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
2.2 13.2 GO:0016887 ATPase activity(GO:0016887)
2.2 28.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
2.1 36.5 GO:0003746 translation elongation factor activity(GO:0003746)
2.1 12.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.1 119.5 GO:0070063 RNA polymerase binding(GO:0070063)
2.0 4.1 GO:0043398 HLH domain binding(GO:0043398)
2.0 30.2 GO:0032036 myosin heavy chain binding(GO:0032036)
2.0 3.9 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
1.9 31.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
1.9 27.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.9 30.7 GO:0004526 ribonuclease P activity(GO:0004526)
1.9 13.4 GO:0031386 protein tag(GO:0031386)
1.9 37.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
1.9 39.7 GO:0003924 GTPase activity(GO:0003924)
1.9 22.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.9 24.1 GO:0044548 S100 protein binding(GO:0044548)
1.8 21.9 GO:0005131 growth hormone receptor binding(GO:0005131)
1.8 12.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.8 18.2 GO:0015232 heme transporter activity(GO:0015232)
1.8 85.9 GO:0004364 glutathione transferase activity(GO:0004364)
1.8 49.9 GO:0071889 14-3-3 protein binding(GO:0071889)
1.8 16.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.8 29.9 GO:0043274 phospholipase binding(GO:0043274)
1.8 105.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
1.8 80.6 GO:0016836 hydro-lyase activity(GO:0016836)
1.7 36.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.6 70.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
1.6 4.8 GO:0015616 DNA translocase activity(GO:0015616)
1.6 2160.4 GO:0003723 RNA binding(GO:0003723)
1.6 25.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
1.6 28.4 GO:0070410 co-SMAD binding(GO:0070410)
1.6 11.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.5 84.8 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
1.5 17.4 GO:0045294 alpha-catenin binding(GO:0045294)
1.4 5.8 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.4 5.8 GO:0001222 transcription corepressor binding(GO:0001222)
1.4 15.5 GO:0016783 sulfurtransferase activity(GO:0016783)
1.4 47.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
1.4 19.1 GO:0030215 semaphorin receptor binding(GO:0030215)
1.3 2.7 GO:0043522 leucine zipper domain binding(GO:0043522)
1.3 12.9 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
1.3 16.7 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.3 6.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106) ubiquitin-protein transferase activator activity(GO:0097027)
1.3 15.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
1.3 8.8 GO:0051087 chaperone binding(GO:0051087)
1.3 12.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.2 11.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
1.2 28.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
1.2 36.5 GO:0031593 polyubiquitin binding(GO:0031593)
1.2 37.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.2 2.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.2 36.8 GO:0015248 sterol transporter activity(GO:0015248)
1.2 2.4 GO:0004040 amidase activity(GO:0004040)
1.2 9.2 GO:0019237 centromeric DNA binding(GO:0019237)
1.1 21.6 GO:0046965 retinoid X receptor binding(GO:0046965)
1.1 12.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.1 71.5 GO:0051082 unfolded protein binding(GO:0051082)
1.1 55.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
1.1 6.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.1 41.0 GO:0005080 protein kinase C binding(GO:0005080)
1.0 13.6 GO:0042608 T cell receptor binding(GO:0042608)
1.0 14.5 GO:0017049 GTP-Rho binding(GO:0017049)
1.0 222.0 GO:0003714 transcription corepressor activity(GO:0003714)
1.0 2.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.0 3.8 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.9 3.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.8 8.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.8 28.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.8 3.3 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.8 178.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.7 5.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.7 2.8 GO:0005499 vitamin D binding(GO:0005499)
0.7 15.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.7 2.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.6 3.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.6 3.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.6 56.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.6 12.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.6 5.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 49.9 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.6 10.8 GO:0070840 dynein complex binding(GO:0070840)
0.6 17.2 GO:0042605 peptide antigen binding(GO:0042605)
0.6 6.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.5 1.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.5 10.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.5 42.2 GO:0008565 protein transporter activity(GO:0008565)
0.5 11.7 GO:0051117 ATPase binding(GO:0051117)
0.5 8.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.5 5.2 GO:0097602 cullin family protein binding(GO:0097602)
0.5 0.9 GO:0050072 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) m7G(5')pppN diphosphatase activity(GO:0050072) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.5 15.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.4 4.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.4 47.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 25.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 9.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 33.4 GO:0009055 electron carrier activity(GO:0009055)
0.3 2.4 GO:0003712 transcription cofactor activity(GO:0003712)
0.3 9.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 24.0 GO:0003777 microtubule motor activity(GO:0003777)
0.3 1.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3 8.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 44.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 14.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.3 6.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 15.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2 61.4 GO:0005525 GTP binding(GO:0005525)
0.2 6.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 6.2 GO:0008013 beta-catenin binding(GO:0008013)
0.2 10.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 84.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 27.6 GO:0008201 heparin binding(GO:0008201)
0.2 8.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.2 4.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 2.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.7 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 6.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 5.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.3 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 3.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 7.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 67.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
9.0 17.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
6.5 443.1 PID PLK1 PATHWAY PLK1 signaling events
5.3 79.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
5.2 235.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
5.0 287.2 PID AURORA B PATHWAY Aurora B signaling
4.6 187.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
4.4 96.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
4.0 158.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
3.5 88.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
3.3 88.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
3.1 77.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
3.0 44.9 PID ATM PATHWAY ATM pathway
3.0 291.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
2.7 21.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
2.4 95.8 PID EPHB FWD PATHWAY EPHB forward signaling
2.3 268.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
2.2 50.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
2.2 99.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
2.1 205.1 PID CDC42 PATHWAY CDC42 signaling events
2.0 77.0 PID TRAIL PATHWAY TRAIL signaling pathway
1.9 84.0 PID FOXO PATHWAY FoxO family signaling
1.9 44.7 PID AURORA A PATHWAY Aurora A signaling
1.8 38.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
1.8 57.8 PID IL1 PATHWAY IL1-mediated signaling events
1.8 83.9 PID P53 REGULATION PATHWAY p53 pathway
1.8 49.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
1.7 40.4 PID IL3 PATHWAY IL3-mediated signaling events
1.7 112.8 PID HNF3A PATHWAY FOXA1 transcription factor network
1.7 165.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
1.5 18.3 PID BARD1 PATHWAY BARD1 signaling events
1.3 62.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.2 48.3 PID NCADHERIN PATHWAY N-cadherin signaling events
1.2 25.1 PID IFNG PATHWAY IFN-gamma pathway
1.2 55.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
1.2 71.5 PID E2F PATHWAY E2F transcription factor network
1.1 32.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.1 49.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
1.1 20.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
1.0 17.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.9 52.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.9 122.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.9 29.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.9 16.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.9 10.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.7 30.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.7 29.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.7 44.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.7 7.2 ST GA13 PATHWAY G alpha 13 Pathway
0.6 25.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.6 28.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.5 13.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.5 8.2 PID ALK2 PATHWAY ALK2 signaling events
0.5 12.5 PID IL23 PATHWAY IL23-mediated signaling events
0.4 27.2 PID CMYB PATHWAY C-MYB transcription factor network
0.4 17.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.4 3.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.4 3.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 6.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.3 7.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 18.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.3 5.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 5.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.2 4.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 6.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 6.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 2.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 5.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 16.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
11.3 258.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
10.1 857.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
9.9 357.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
9.5 95.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
8.7 78.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
8.7 52.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
8.6 267.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
8.6 77.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
8.6 34.3 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
8.5 381.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
8.1 634.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
7.8 305.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
7.8 140.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
7.4 126.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
7.4 88.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
6.7 134.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
6.6 72.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
6.6 190.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
6.5 96.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
6.3 188.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
6.1 202.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
6.1 42.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
6.1 680.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
6.0 72.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
6.0 137.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
5.5 94.3 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
5.1 144.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
4.9 191.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
4.9 127.1 REACTOME KINESINS Genes involved in Kinesins
4.8 1123.5 REACTOME TRANSLATION Genes involved in Translation
4.6 78.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
4.6 73.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
4.5 49.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
4.4 151.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
4.0 36.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
3.9 90.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
3.8 53.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
3.8 22.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
3.7 54.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.2 51.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
3.1 44.0 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
3.1 76.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
3.0 39.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
3.0 47.6 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
3.0 62.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
2.8 25.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
2.8 252.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
2.6 13.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
2.6 139.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
2.5 68.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
2.5 63.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
2.4 95.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
2.4 63.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
2.3 154.6 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
2.2 13.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
2.2 21.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
2.2 28.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
2.2 26.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
2.1 44.3 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
2.1 33.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
2.1 60.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
2.1 37.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
2.0 74.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
1.8 43.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
1.8 55.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
1.8 275.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.7 17.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.6 36.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
1.6 15.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.6 18.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
1.5 6.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
1.5 31.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
1.5 38.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.4 31.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.4 84.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
1.4 40.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.4 78.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
1.3 83.4 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
1.3 16.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.1 33.6 REACTOME G1 PHASE Genes involved in G1 Phase
1.1 15.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
1.0 6.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
1.0 3.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
1.0 18.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.9 53.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.9 7.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.9 10.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.8 7.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.8 13.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8 23.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.7 20.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.6 29.7 REACTOME DNA REPAIR Genes involved in DNA Repair
0.6 11.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.5 30.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.5 11.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.4 19.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 8.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.4 10.0 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.4 6.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 4.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.3 13.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 12.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 10.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 14.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.3 23.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 10.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 29.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 3.0 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.2 3.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 5.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 17.9 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 3.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 18.9 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions