ISMARA results: TEAD3

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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TEAD3_TEAD1

Z-value: 3.38

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Transcription factors associated with TEAD3_TEAD1

Gene Symbol	Gene ID	Gene Info
TEAD3 Ensembl NCBI GeneCards UniProt	ENSG00000007866.14	TEA domain transcription factor 3
TEAD1 Ensembl NCBI GeneCards UniProt	ENSG00000187079.10	TEA domain transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TEAD3	hg19_v2_chr6_-_35464727_35464738, hg19_v2_chr6_-_35464817_35464894	0.58	3.8e-21	Click!
TEAD1	hg19_v2_chr11_+_12766583_12766592, hg19_v2_chr11_+_12696102_12696164, hg19_v2_chr11_+_12695944_12695989	0.53	2.3e-17	Click!

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_-_132272504 Show fit	208.59	ENST00000367976.3	CTGF Ensembl NCBI GeneCards UniProt Show fit	connective tissue growth factor
chr10_-_90712520 Show fit	124.85	ENST00000224784.6	ACTA2 Ensembl NCBI GeneCards UniProt Show fit	actin, alpha 2, smooth muscle, aorta
chr1_+_86046433 Show fit	81.33	ENST00000451137.2	CYR61 Ensembl NCBI GeneCards UniProt Show fit	cysteine-rich, angiogenic inducer, 61
chr11_-_111781454 Show fit	64.46	ENST00000533280.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr7_+_134464414 Show fit	60.30	ENST00000361901.2	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr5_-_39425068 Show fit	55.00	ENST00000515700.1 ENST00000339788.6	DAB2 Ensembl NCBI GeneCards UniProt Show fit	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_-_40575535 Show fit	54.30	ENST00000357037.5	PTRF Ensembl NCBI GeneCards UniProt Show fit	polymerase I and transcript release factor
chr1_-_95391315 Show fit	54.17	ENST00000545882.1 ENST00000415017.1	CNN3 Ensembl NCBI GeneCards UniProt Show fit	calponin 3, acidic
chr15_+_63334831 Show fit	53.57	ENST00000288398.6 ENST00000358278.3 ENST00000560445.1 ENST00000403994.3 ENST00000357980.4 ENST00000559556.1 ENST00000559397.1 ENST00000267996.7 ENST00000560970.1	TPM1 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 1 (alpha)
chr2_-_216257849 Show fit	50.57	ENST00000456923.1	FN1 Ensembl NCBI GeneCards UniProt Show fit	fibronectin 1
chr4_+_184020398 Show fit	49.41	ENST00000403733.3 ENST00000378925.3	WWC2 Ensembl NCBI GeneCards UniProt Show fit	WW and C2 domain containing 2
chr7_+_116165754 Show fit	48.02	ENST00000405348.1	CAV1 Ensembl NCBI GeneCards UniProt Show fit	caveolin 1, caveolae protein, 22kDa
chr12_-_7245125 Show fit	47.99	ENST00000542285.1 ENST00000540610.1	C1R Ensembl NCBI GeneCards UniProt Show fit	complement component 1, r subcomponent
chr20_+_35169885 Show fit	41.58	ENST00000279022.2 ENST00000346786.2	MYL9 Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 9, regulatory
chr15_+_39873268 Show fit	40.99	ENST00000397591.2 ENST00000260356.5	THBS1 Ensembl NCBI GeneCards UniProt Show fit	thrombospondin 1
chr7_+_134464376 Show fit	40.78	ENST00000454108.1 ENST00000361675.2	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr7_+_128470431 Show fit	40.78	ENST00000325888.8 ENST00000346177.6	FLNC Ensembl NCBI GeneCards UniProt Show fit	filamin C, gamma
chr15_+_96869165 Show fit	38.36	ENST00000421109.2	NR2F2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2, group F, member 2
chr6_+_30850697 Show fit	38.17	ENST00000509639.1 ENST00000412274.2 ENST00000507901.1 ENST00000507046.1 ENST00000437124.2 ENST00000454612.2 ENST00000396342.2	DDR1 Ensembl NCBI GeneCards UniProt Show fit	discoidin domain receptor tyrosine kinase 1
chr8_+_144816303 Show fit	37.45	ENST00000533004.1	FAM83H-AS1 Ensembl NCBI GeneCards UniProt Show fit	FAM83H antisense RNA 1 (head to head)
chr1_-_1293904 Show fit	36.48	ENST00000309212.6 ENST00000342753.4 ENST00000445648.2	MXRA8 Ensembl NCBI GeneCards UniProt Show fit	matrix-remodelling associated 8
chr11_-_111782696 Show fit	36.03	ENST00000227251.3 ENST00000526180.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr6_+_83073334 Show fit	35.20	ENST00000369750.3	TPBG Ensembl NCBI GeneCards UniProt Show fit	trophoblast glycoprotein
chr5_-_39425222 Show fit	35.05	ENST00000320816.6	DAB2 Ensembl NCBI GeneCards UniProt Show fit	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr7_+_116165038 Show fit	34.97	ENST00000393470.1	CAV1 Ensembl NCBI GeneCards UniProt Show fit	caveolin 1, caveolae protein, 22kDa
chr6_+_83072923 Show fit	34.90	ENST00000535040.1	TPBG Ensembl NCBI GeneCards UniProt Show fit	trophoblast glycoprotein
chr11_-_111781610 Show fit	34.60	ENST00000525823.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr5_-_39425290 Show fit	34.50	ENST00000545653.1	DAB2 Ensembl NCBI GeneCards UniProt Show fit	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_+_20059302 Show fit	32.70	ENST00000395530.2	SPECC1 Ensembl NCBI GeneCards UniProt Show fit	sperm antigen with calponin homology and coiled-coil domains 1
chr11_-_111782484 Show fit	32.43	ENST00000533971.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr3_-_134093275 Show fit	31.78	ENST00000513145.1 ENST00000422605.2	AMOTL2 Ensembl NCBI GeneCards UniProt Show fit	angiomotin like 2
chr7_+_100464760 Show fit	31.46	ENST00000200457.4	TRIP6 Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 6
chr4_-_187644930 Show fit	31.32	ENST00000441802.2	FAT1 Ensembl NCBI GeneCards UniProt Show fit	FAT atypical cadherin 1
chr11_+_114166536 Show fit	31.30	ENST00000299964.3	NNMT Ensembl NCBI GeneCards UniProt Show fit	nicotinamide N-methyltransferase
chr10_-_33247124 Show fit	31.28	ENST00000414670.1 ENST00000302278.3 ENST00000374956.4 ENST00000488494.1 ENST00000417122.2 ENST00000474568.1	ITGB1 Ensembl NCBI GeneCards UniProt Show fit	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr11_-_111781554 Show fit	31.17	ENST00000526167.1 ENST00000528961.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr15_-_60690163 Show fit	31.03	ENST00000558998.1 ENST00000560165.1 ENST00000557986.1 ENST00000559780.1 ENST00000559467.1 ENST00000559956.1 ENST00000332680.4 ENST00000396024.3 ENST00000421017.2 ENST00000560466.1 ENST00000558132.1 ENST00000559113.1 ENST00000557906.1 ENST00000558558.1 ENST00000560468.1 ENST00000559370.1 ENST00000558169.1 ENST00000559725.1 ENST00000558985.1 ENST00000451270.2	ANXA2 Ensembl NCBI GeneCards UniProt Show fit	annexin A2
chr3_-_134093395 Show fit	30.15	ENST00000249883.5	AMOTL2 Ensembl NCBI GeneCards UniProt Show fit	angiomotin like 2
chr3_-_114343039 Show fit	29.72	ENST00000481632.1	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr10_-_99447024 Show fit	27.32	ENST00000370626.3	AVPI1 Ensembl NCBI GeneCards UniProt Show fit	arginine vasopressin-induced 1
chr5_-_55290773 Show fit	26.96	ENST00000502326.3 ENST00000381298.2	IL6ST Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr1_-_201438282 Show fit	26.86	ENST00000367311.3 ENST00000367309.1	PHLDA3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology-like domain, family A, member 3
chrX_-_10588459 Show fit	26.71	ENST00000380782.2	MID1 Ensembl NCBI GeneCards UniProt Show fit	midline 1 (Opitz/BBB syndrome)
chr1_-_94050668 Show fit	24.97	ENST00000539242.1	BCAR3 Ensembl NCBI GeneCards UniProt Show fit	breast cancer anti-estrogen resistance 3
chr10_+_123872483 Show fit	23.65	ENST00000369001.1	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming, acidic coiled-coil containing protein 2
chr1_-_16344500 Show fit	23.49	ENST00000406363.2 ENST00000411503.1 ENST00000545268.1 ENST00000487046.1	HSPB7 Ensembl NCBI GeneCards UniProt Show fit	heat shock 27kDa protein family, member 7 (cardiovascular)
chr11_-_14379997 Show fit	23.47	ENST00000526063.1 ENST00000532814.1	RRAS2 Ensembl NCBI GeneCards UniProt Show fit	related RAS viral (r-ras) oncogene homolog 2
chr3_-_127541194 Show fit	23.42	ENST00000453507.2	MGLL Ensembl NCBI GeneCards UniProt Show fit	monoglyceride lipase
chr7_+_134430212 Show fit	22.51	ENST00000436461.2	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr1_-_161279749 Show fit	22.46	ENST00000533357.1 ENST00000360451.6 ENST00000336559.4	MPZ Ensembl NCBI GeneCards UniProt Show fit	myelin protein zero
chr4_-_186733363 Show fit	22.13	ENST00000393523.2 ENST00000393528.3 ENST00000449407.2	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr16_-_122619 Show fit	21.77	ENST00000262316.6	RHBDF1 Ensembl NCBI GeneCards UniProt Show fit	rhomboid 5 homolog 1 (Drosophila)
chr11_+_92085707 Show fit	21.27	ENST00000525166.1	FAT3 Ensembl NCBI GeneCards UniProt Show fit	FAT atypical cadherin 3
chr6_-_128841503 Show fit	21.18	ENST00000368215.3 ENST00000532331.1 ENST00000368213.5 ENST00000368207.3 ENST00000525459.1 ENST00000368210.3 ENST00000368226.4 ENST00000368227.3	PTPRK Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, receptor type, K
chr19_-_14606900 Show fit	20.18	ENST00000393029.3 ENST00000393028.1 ENST00000393033.4 ENST00000345425.2 ENST00000586027.1 ENST00000591349.1 ENST00000587210.1	GIPC1 Ensembl NCBI GeneCards UniProt Show fit	GIPC PDZ domain containing family, member 1
chr11_+_92577506 Show fit	19.65	ENST00000533797.1	FAT3 Ensembl NCBI GeneCards UniProt Show fit	FAT atypical cadherin 3
chr19_+_33182823 Show fit	18.65	ENST00000397061.3	NUDT19 Ensembl NCBI GeneCards UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr12_-_8815299 Show fit	18.42	ENST00000535336.1	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar associated protein 5
chr11_+_66824276 Show fit	18.36	ENST00000308831.2	RHOD Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member D
chr19_+_45409011 Show fit	18.18	ENST00000252486.4 ENST00000446996.1 ENST00000434152.1	APOE Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein E
chr1_-_16482554 Show fit	18.00	ENST00000358432.5	EPHA2 Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A2
chr12_-_8815215 Show fit	17.77	ENST00000544889.1 ENST00000543369.1	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar associated protein 5
chr11_+_92085262 Show fit	17.51	ENST00000298047.6 ENST00000409404.2 ENST00000541502.1	FAT3 Ensembl NCBI GeneCards UniProt Show fit	FAT atypical cadherin 3
chr3_-_128712955 Show fit	17.48	ENST00000265068.5	KIAA1257 Ensembl NCBI GeneCards UniProt Show fit	KIAA1257
chr15_-_48937982 Show fit	17.29	ENST00000316623.5	FBN1 Ensembl NCBI GeneCards UniProt Show fit	fibrillin 1
chr4_+_41614909 Show fit	17.09	ENST00000509454.1 ENST00000396595.3 ENST00000381753.4	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr19_-_17185848 Show fit	16.59	ENST00000593360.1	HAUS8 Ensembl NCBI GeneCards UniProt Show fit	HAUS augmin-like complex, subunit 8
chr2_-_190044480 Show fit	16.53	ENST00000374866.3	COL5A2 Ensembl NCBI GeneCards UniProt Show fit	collagen, type V, alpha 2
chr14_-_23904861 Show fit	16.49	ENST00000355349.3	MYH7 Ensembl NCBI GeneCards UniProt Show fit	myosin, heavy chain 7, cardiac muscle, beta
chr6_-_35464817 Show fit	16.21	ENST00000338863.7	TEAD3 Ensembl NCBI GeneCards UniProt Show fit	TEA domain family member 3
chr6_-_35464727 Show fit	15.81	ENST00000402886.3	TEAD3 Ensembl NCBI GeneCards UniProt Show fit	TEA domain family member 3
chr4_+_41614720 Show fit	15.43	ENST00000509277.1	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr17_+_4901199 Show fit	15.08	ENST00000320785.5 ENST00000574165.1	KIF1C Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 1C
chr2_-_217560248 Show fit	14.83	ENST00000233813.4	IGFBP5 Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor binding protein 5
chr6_-_30712313 Show fit	14.58	ENST00000376377.2 ENST00000259874.5	IER3 Ensembl NCBI GeneCards UniProt Show fit	immediate early response 3
chr4_+_169552748 Show fit	14.45	ENST00000504519.1 ENST00000512127.1	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr1_-_59043166 Show fit	14.40	ENST00000371225.2	TACSTD2 Ensembl NCBI GeneCards UniProt Show fit	tumor-associated calcium signal transducer 2
chr20_-_44540686 Show fit	14.30	ENST00000477313.1 ENST00000542937.1 ENST00000372431.3 ENST00000354050.4 ENST00000420868.2	PLTP Ensembl NCBI GeneCards UniProt Show fit	phospholipid transfer protein
chr7_-_137686791 Show fit	14.01	ENST00000452463.1 ENST00000330387.6 ENST00000456390.1	CREB3L2 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 3-like 2
chr3_+_147127142 Show fit	13.99	ENST00000282928.4	ZIC1 Ensembl NCBI GeneCards UniProt Show fit	Zic family member 1
chrX_-_10851762 Show fit	13.94	ENST00000380785.1 ENST00000380787.1	MID1 Ensembl NCBI GeneCards UniProt Show fit	midline 1 (Opitz/BBB syndrome)
chr11_-_8832182 Show fit	13.90	ENST00000527510.1 ENST00000528527.1 ENST00000528523.1 ENST00000313726.6	ST5 Ensembl NCBI GeneCards UniProt Show fit	suppression of tumorigenicity 5
chr19_+_15218180 Show fit	13.81	ENST00000342784.2 ENST00000597977.1 ENST00000600440.1	SYDE1 Ensembl NCBI GeneCards UniProt Show fit	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr18_+_21693306 Show fit	13.40	ENST00000540918.2	TTC39C Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 39C
chr7_+_102715315 Show fit	13.22	ENST00000428183.2 ENST00000323716.3 ENST00000441711.2 ENST00000454559.1 ENST00000425331.1 ENST00000541300.1	ARMC10 Ensembl NCBI GeneCards UniProt Show fit	armadillo repeat containing 10
chr1_+_196621002 Show fit	13.14	ENST00000367429.4 ENST00000439155.2	CFH Ensembl NCBI GeneCards UniProt Show fit	complement factor H
chr8_+_70378852 Show fit	12.98	ENST00000525061.1 ENST00000458141.2 ENST00000260128.4	SULF1 Ensembl NCBI GeneCards UniProt Show fit	sulfatase 1
chr11_-_76381029 Show fit	12.68	ENST00000407242.2 ENST00000421973.1	LRRC32 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 32
chr8_-_82395461 Show fit	12.58	ENST00000256104.4	FABP4 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 4, adipocyte
chr17_+_37856299 Show fit	12.53	ENST00000269571.5	ERBB2 Ensembl NCBI GeneCards UniProt Show fit	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr3_-_185538849 Show fit	12.49	ENST00000421047.2	IGF2BP2 Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor 2 mRNA binding protein 2
chr9_-_14314518 Show fit	12.40	ENST00000397581.2	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I/B
chr9_-_14314566 Show fit	12.24	ENST00000397579.2	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I/B
chr17_-_39677971 Show fit	12.23	ENST00000393976.2	KRT15 Ensembl NCBI GeneCards UniProt Show fit	keratin 15
chr19_-_50143452 Show fit	12.22	ENST00000246792.3	RRAS Ensembl NCBI GeneCards UniProt Show fit	related RAS viral (r-ras) oncogene homolog
chr9_+_118916082 Show fit	12.06	ENST00000328252.3	PAPPA Ensembl NCBI GeneCards UniProt Show fit	pregnancy-associated plasma protein A, pappalysin 1
chr12_-_8815404 Show fit	11.77	ENST00000359478.2 ENST00000396549.2	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar associated protein 5
chr7_+_26438187 Show fit	11.63	ENST00000439120.1 ENST00000430548.1 ENST00000421862.1 ENST00000449537.1 ENST00000420774.1 ENST00000418758.2	AC004540.5 Ensembl NCBI GeneCards UniProt Show fit	AC004540.5
chr2_+_189157536 Show fit	11.53	ENST00000409580.1 ENST00000409637.3	GULP1 Ensembl NCBI GeneCards UniProt Show fit	GULP, engulfment adaptor PTB domain containing 1
chr6_+_134210243 Show fit	11.51	ENST00000367882.4	TCF21 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 21
chr2_+_102759199 Show fit	11.43	ENST00000409288.1 ENST00000410023.1	IL1R1 Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor, type I
chr2_+_189157498 Show fit	11.36	ENST00000359135.3	GULP1 Ensembl NCBI GeneCards UniProt Show fit	GULP, engulfment adaptor PTB domain containing 1
chr3_-_48057890 Show fit	11.33	ENST00000434267.1	MAP4 Ensembl NCBI GeneCards UniProt Show fit	microtubule-associated protein 4
chr5_-_43412418 Show fit	11.15	ENST00000537013.1 ENST00000361115.4	CCL28 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 28
chr1_+_150229554 Show fit	10.93	ENST00000369111.4	CA14 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase XIV
chr12_-_54813229 Show fit	10.74	ENST00000293379.4	ITGA5 Ensembl NCBI GeneCards UniProt Show fit	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_229569834 Show fit	10.73	ENST00000366684.3 ENST00000366683.2	ACTA1 Ensembl NCBI GeneCards UniProt Show fit	actin, alpha 1, skeletal muscle
chr12_+_27677085 Show fit	10.71	ENST00000545334.1 ENST00000540114.1 ENST00000537927.1 ENST00000318304.8 ENST00000535047.1 ENST00000542629.1 ENST00000228425.6	PPFIBP1 Ensembl NCBI GeneCards UniProt Show fit	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr1_+_196621156 Show fit	10.66	ENST00000359637.2	CFH Ensembl NCBI GeneCards UniProt Show fit	complement factor H
chr15_+_63354769 Show fit	10.61	ENST00000558910.1	TPM1 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 1 (alpha)
chr16_+_30387141 Show fit	10.42	ENST00000566955.1	MYLPF Ensembl NCBI GeneCards UniProt Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr4_-_186877806 Show fit	10.32	ENST00000355634.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr3_-_149375783 Show fit	10.18	ENST00000467467.1 ENST00000460517.1 ENST00000360632.3	WWTR1 Ensembl NCBI GeneCards UniProt Show fit	WW domain containing transcription regulator 1
chr17_+_37856253 Show fit	10.06	ENST00000540147.1 ENST00000584450.1	ERBB2 Ensembl NCBI GeneCards UniProt Show fit	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr5_+_140868717 Show fit	9.98	ENST00000252087.1	PCDHGC5 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily C, 5
chr10_-_33625154 Show fit	9.93	ENST00000265371.4	NRP1 Ensembl NCBI GeneCards UniProt Show fit	neuropilin 1
chr13_-_33760216 Show fit	9.86	ENST00000255486.4	STARD13 Ensembl NCBI GeneCards UniProt Show fit	StAR-related lipid transfer (START) domain containing 13
chr17_-_73505961 Show fit	9.81	ENST00000433559.2	CASKIN2 Ensembl NCBI GeneCards UniProt Show fit	CASK interacting protein 2
chr12_-_111358372 Show fit	9.71	ENST00000548438.1 ENST00000228841.8	MYL2 Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 2, regulatory, cardiac, slow
chr11_+_46299199 Show fit	9.68	ENST00000529193.1 ENST00000288400.3	CREB3L1 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 3-like 1
chr4_+_176986978 Show fit	9.67	ENST00000508596.1 ENST00000393643.2	WDR17 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 17
chr8_+_97597148 Show fit	9.60	ENST00000521590.1	SDC2 Ensembl NCBI GeneCards UniProt Show fit	syndecan 2
chr4_-_186877502 Show fit	9.46	ENST00000431902.1 ENST00000284776.7 ENST00000415274.1	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr1_-_94079648 Show fit	9.29	ENST00000370247.3	BCAR3 Ensembl NCBI GeneCards UniProt Show fit	breast cancer anti-estrogen resistance 3
chr1_+_114522049 Show fit	9.24	ENST00000369551.1 ENST00000320334.4	OLFML3 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin-like 3
chr9_-_16727978 Show fit	9.14	ENST00000418777.1 ENST00000468187.2	BNC2 Ensembl NCBI GeneCards UniProt Show fit	basonuclin 2
chr17_-_73511584 Show fit	9.10	ENST00000321617.3	CASKIN2 Ensembl NCBI GeneCards UniProt Show fit	CASK interacting protein 2
chr11_-_111170526 Show fit	9.10	ENST00000355430.4	COLCA1 Ensembl NCBI GeneCards UniProt Show fit	colorectal cancer associated 1
chr18_+_3247779 Show fit	8.89	ENST00000578611.1 ENST00000583449.1	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 12A, regulatory, non-sarcomeric
chr10_-_17659234 Show fit	8.83	ENST00000466335.1	PTPLA Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr18_-_25616519 Show fit	8.76	ENST00000399380.3	CDH2 Ensembl NCBI GeneCards UniProt Show fit	cadherin 2, type 1, N-cadherin (neuronal)
chr17_-_39093672 Show fit	8.58	ENST00000209718.3 ENST00000436344.3 ENST00000485751.1	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23 (histone deacetylase inducible)
chr1_+_62417957 Show fit	8.57	ENST00000307297.7 ENST00000543708.1	INADL Ensembl NCBI GeneCards UniProt Show fit	InaD-like (Drosophila)
chr1_-_11918988 Show fit	8.50	ENST00000376468.3	NPPB Ensembl NCBI GeneCards UniProt Show fit	natriuretic peptide B
chr1_-_201915590 Show fit	8.48	ENST00000367288.4	LMOD1 Ensembl NCBI GeneCards UniProt Show fit	leiomodin 1 (smooth muscle)
chr8_-_38325219 Show fit	8.35	ENST00000533668.1 ENST00000413133.2 ENST00000397108.4 ENST00000526742.1 ENST00000525001.1 ENST00000425967.3 ENST00000529552.1 ENST00000397113.2	FGFR1 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor receptor 1
chr17_+_57232690 Show fit	8.04	ENST00000262293.4	PRR11 Ensembl NCBI GeneCards UniProt Show fit	proline rich 11
chr18_+_3247413 Show fit	7.96	ENST00000579226.1 ENST00000217652.3	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 12A, regulatory, non-sarcomeric
chr17_+_70117153 Show fit	7.89	ENST00000245479.2	SOX9 Ensembl NCBI GeneCards UniProt Show fit	SRY (sex determining region Y)-box 9
chr6_+_118869452 Show fit	7.85	ENST00000357525.5	PLN Ensembl NCBI GeneCards UniProt Show fit	phospholamban
chr16_+_30386098 Show fit	7.79	ENST00000322861.7	MYLPF Ensembl NCBI GeneCards UniProt Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr5_-_150138551 Show fit	7.70	ENST00000446090.2 ENST00000447998.2	DCTN4 Ensembl NCBI GeneCards UniProt Show fit	dynactin 4 (p62)
chr15_+_33010175 Show fit	7.65	ENST00000300177.4 ENST00000560677.1 ENST00000560830.1	GREM1 Ensembl NCBI GeneCards UniProt Show fit	gremlin 1, DAN family BMP antagonist
chr6_+_148663729 Show fit	7.64	ENST00000367467.3	SASH1 Ensembl NCBI GeneCards UniProt Show fit	SAM and SH3 domain containing 1
chr2_+_30569506 Show fit	7.57	ENST00000421976.2	AC109642.1 Ensembl NCBI GeneCards UniProt Show fit	AC109642.1
chr6_-_3157760 Show fit	7.54	ENST00000333628.3	TUBB2A Ensembl NCBI GeneCards UniProt Show fit	tubulin, beta 2A class IIa
chr19_+_39138320 Show fit	7.53	ENST00000424234.2 ENST00000390009.3 ENST00000589528.1	ACTN4 Ensembl NCBI GeneCards UniProt Show fit	actinin, alpha 4
chr8_-_119124045 Show fit	7.52	ENST00000378204.2	EXT1 Ensembl NCBI GeneCards UniProt Show fit	exostosin glycosyltransferase 1
chr17_+_73717551 Show fit	7.44	ENST00000450894.3	ITGB4 Ensembl NCBI GeneCards UniProt Show fit	integrin, beta 4
chr9_-_113341985 Show fit	7.31	ENST00000374469.1	SVEP1 Ensembl NCBI GeneCards UniProt Show fit	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr9_-_14308004 Show fit	7.28	ENST00000493697.1	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I/B
chr17_+_73717407 Show fit	7.28	ENST00000579662.1	ITGB4 Ensembl NCBI GeneCards UniProt Show fit	integrin, beta 4
chr15_+_74466744 Show fit	7.27	ENST00000560862.1 ENST00000395118.1	ISLR Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily containing leucine-rich repeat
chr4_-_186732048 Show fit	7.16	ENST00000448662.2 ENST00000439049.1 ENST00000420158.1 ENST00000431808.1 ENST00000319471.9	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr12_+_52445191 Show fit	7.06	ENST00000243050.1 ENST00000394825.1 ENST00000550763.1 ENST00000394824.2 ENST00000548232.1 ENST00000562373.1	NR4A1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 4, group A, member 1
chr11_-_47470703 Show fit	7.00	ENST00000298854.2	RAPSN Ensembl NCBI GeneCards UniProt Show fit	receptor-associated protein of the synapse
chr11_+_111782934 Show fit	7.00	ENST00000304298.3	HSPB2 Ensembl NCBI GeneCards UniProt Show fit	Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr11_+_46316677 Show fit	6.98	ENST00000534787.1	CREB3L1 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 3-like 1
chr19_+_39138271 Show fit	6.96	ENST00000252699.2	ACTN4 Ensembl NCBI GeneCards UniProt Show fit	actinin, alpha 4
chr19_+_676385 Show fit	6.95	ENST00000166139.4	FSTL3 Ensembl NCBI GeneCards UniProt Show fit	follistatin-like 3 (secreted glycoprotein)
chr7_+_30960915 Show fit	6.85	ENST00000441328.2 ENST00000409899.1 ENST00000409611.1	AQP1 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 1 (Colton blood group)
chr2_-_211179883 Show fit	6.82	ENST00000352451.3	MYL1 Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 1, alkali; skeletal, fast
chr11_-_47470682 Show fit	6.80	ENST00000529341.1 ENST00000352508.3	RAPSN Ensembl NCBI GeneCards UniProt Show fit	receptor-associated protein of the synapse
chr18_+_7754957 Show fit	6.76	ENST00000400053.4	PTPRM Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, receptor type, M
chr9_+_139873264 Show fit	6.66	ENST00000446677.1	PTGDS Ensembl NCBI GeneCards UniProt Show fit	prostaglandin D2 synthase 21kDa (brain)
chr4_+_166300084 Show fit	6.62	ENST00000402744.4	CPE Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase E
chr15_+_41136216 Show fit	6.49	ENST00000562057.1 ENST00000344051.4	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr9_-_13175823 Show fit	6.48	ENST00000545857.1	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain protein
chr15_+_41136586 Show fit	6.38	ENST00000431806.1	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr4_+_165675269 Show fit	6.35	ENST00000507311.1	RP11-294O2.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-294O2.2
chrX_-_41449204 Show fit	6.18	ENST00000378179.3	CASK Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr12_+_32655048 Show fit	6.09	ENST00000427716.2 ENST00000266482.3	FGD4 Ensembl NCBI GeneCards UniProt Show fit	FYVE, RhoGEF and PH domain containing 4
chr7_-_135412925 Show fit	6.08	ENST00000354042.4	SLC13A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 13 (sodium/sulfate symporter), member 4
chr9_+_112542572 Show fit	6.04	ENST00000374530.3	PALM2-AKAP2 Ensembl NCBI GeneCards UniProt Show fit	PALM2-AKAP2 readthrough
chr8_-_141728760 Show fit	6.03	ENST00000430260.2	PTK2 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2
chr12_-_104443890 Show fit	6.01	ENST00000547583.1 ENST00000360814.4 ENST00000546851.1	GLT8D2 Ensembl NCBI GeneCards UniProt Show fit	glycosyltransferase 8 domain containing 2
chr3_+_38347427 Show fit	5.96	ENST00000273173.4	SLC22A14 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 22, member 14
chr11_+_101981169 Show fit	5.95	ENST00000526343.1 ENST00000282441.5 ENST00000537274.1 ENST00000345877.2	YAP1 Ensembl NCBI GeneCards UniProt Show fit	Yes-associated protein 1
chr11_-_47470591 Show fit	5.91	ENST00000524487.1	RAPSN Ensembl NCBI GeneCards UniProt Show fit	receptor-associated protein of the synapse
chr10_+_123923205 Show fit	5.87	ENST00000369004.3 ENST00000260733.3	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming, acidic coiled-coil containing protein 2
chr19_+_782755 Show fit	5.86	ENST00000606242.1 ENST00000586061.1	AC006273.5 Ensembl NCBI GeneCards UniProt Show fit	AC006273.5
chr14_+_32546485 Show fit	5.78	ENST00000345122.3 ENST00000432921.1 ENST00000433497.1	ARHGAP5 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 5
chr4_-_175443943 Show fit	5.77	ENST00000296522.6	HPGD Ensembl NCBI GeneCards UniProt Show fit	hydroxyprostaglandin dehydrogenase 15-(NAD)
chr9_+_131314859 Show fit	5.76	ENST00000358161.5 ENST00000372731.4 ENST00000372739.3	SPTAN1 Ensembl NCBI GeneCards UniProt Show fit	spectrin, alpha, non-erythrocytic 1
chr4_+_25657444 Show fit	5.75	ENST00000504570.1 ENST00000382051.3	SLC34A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 34 (type II sodium/phosphate contransporter), member 2
chr1_+_119957554 Show fit	5.68	ENST00000543831.1 ENST00000433745.1 ENST00000369416.3	HSD3B2 Ensembl NCBI GeneCards UniProt Show fit	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chrX_-_135333514 Show fit	5.66	ENST00000370661.1 ENST00000370660.3	MAP7D3 Ensembl NCBI GeneCards UniProt Show fit	MAP7 domain containing 3
chr14_-_89021077 Show fit	5.58	ENST00000556564.1	PTPN21 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, non-receptor type 21
chr14_+_74035763 Show fit	5.57	ENST00000238651.5	ACOT2 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA thioesterase 2
chr1_+_26503894 Show fit	5.57	ENST00000361530.6 ENST00000374253.5	CNKSR1 Ensembl NCBI GeneCards UniProt Show fit	connector enhancer of kinase suppressor of Ras 1
chr19_-_49371711 Show fit	5.53	ENST00000355496.5 ENST00000263265.6	PLEKHA4 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr12_+_3068466 Show fit	5.51	ENST00000358409.2	TEAD4 Ensembl NCBI GeneCards UniProt Show fit	TEA domain family member 4
chr7_-_83278322 Show fit	5.51	ENST00000307792.3	SEMA3E Ensembl NCBI GeneCards UniProt Show fit	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr8_+_120079478 Show fit	5.48	ENST00000332843.2	COLEC10 Ensembl NCBI GeneCards UniProt Show fit	collectin sub-family member 10 (C-type lectin)
chr2_+_32502952 Show fit	5.43	ENST00000238831.4	YIPF4 Ensembl NCBI GeneCards UniProt Show fit	Yip1 domain family, member 4
chr1_+_100818484 Show fit	5.42	ENST00000544534.1	CDC14A Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14A
chr14_-_23877474 Show fit	5.38	ENST00000405093.3	MYH6 Ensembl NCBI GeneCards UniProt Show fit	myosin, heavy chain 6, cardiac muscle, alpha
chr1_+_152974218 Show fit	5.37	ENST00000331860.3 ENST00000443178.1 ENST00000295367.4	SPRR3 Ensembl NCBI GeneCards UniProt Show fit	small proline-rich protein 3
chr5_+_54455946 Show fit	5.34	ENST00000503787.1 ENST00000296734.6 ENST00000515370.1	GPX8 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 8 (putative)
chr10_+_104005272 Show fit	5.30	ENST00000369983.3	GBF1 Ensembl NCBI GeneCards UniProt Show fit	golgi brefeldin A resistant guanine nucleotide exchange factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
69.5	208.6	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
31.1	124.5	GO:0035026	leading edge cell differentiation(GO:0035026)
27.7	83.0	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
22.6	135.6	GO:0090131	mesenchyme migration(GO:0090131)
16.9	50.6	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
13.7	41.0	GO:0002605	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
11.0	198.7	GO:0007021	tubulin complex assembly(GO:0007021)
10.4	31.3	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
10.3	31.0	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
9.6	38.4	GO:0009956	radial pattern formation(GO:0009956)
9.1	18.2	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
9.0	81.3	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278) chondroblast differentiation(GO:0060591)
9.0	18.0	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
8.4	33.7	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
8.0	64.2	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
7.9	7.9	GO:0072197	ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
6.6	19.7	GO:1900073	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
6.4	25.6	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
6.3	31.5	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
5.4	27.1	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
5.3	32.0	GO:0055059	asymmetric neuroblast division(GO:0055059)
4.9	14.8	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
4.8	14.5	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
4.6	31.9	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
4.4	22.0	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
4.2	38.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
4.1	16.5	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
3.8	11.5	GO:0072276	branchiomeric skeletal muscle development(GO:0014707) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
3.8	11.4	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
3.6	14.3	GO:0042360	vitamin E metabolic process(GO:0042360)
3.5	17.3	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
3.5	13.8	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
3.3	23.4	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
3.1	40.6	GO:0035372	protein localization to microtubule(GO:0035372)
2.9	66.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
2.8	8.4	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
2.8	8.4	GO:1903465	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
2.8	16.7	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
2.6	31.3	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
2.5	15.2	GO:0051012	microtubule sliding(GO:0051012)
2.3	4.6	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
2.3	6.9	GO:0072019	carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237)
2.2	15.6	GO:0035331	negative regulation of hippo signaling(GO:0035331)
2.2	11.2	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
2.2	6.6	GO:0032971	regulation of muscle filament sliding(GO:0032971)
2.2	11.1	GO:0010587	miRNA catabolic process(GO:0010587)
2.2	13.0	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
2.1	36.5	GO:0060856	establishment of blood-brain barrier(GO:0060856)
2.1	87.7	GO:0035329	hippo signaling(GO:0035329)
2.1	12.7	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
2.0	4.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
2.0	2.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
2.0	9.9	GO:0060301	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
2.0	9.9	GO:0097498	endothelial tube lumen extension(GO:0097498)
2.0	11.8	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631)
2.0	27.4	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.9	7.6	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
1.8	3.6	GO:0061386	closure of optic fissure(GO:0061386)
1.8	3.6	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
1.8	60.7	GO:0060216	definitive hemopoiesis(GO:0060216)
1.6	34.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
1.6	4.8	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.6	3.2	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
1.5	49.1	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.4	8.5	GO:0051694	pointed-end actin filament capping(GO:0051694)
1.4	6.9	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
1.4	9.6	GO:0008218	bioluminescence(GO:0008218)
1.4	4.1	GO:0007538	primary sex determination(GO:0007538)
1.3	4.0	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533)
1.3	5.3	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.3	6.6	GO:0030070	insulin processing(GO:0030070)
1.3	8.9	GO:0060480	lung goblet cell differentiation(GO:0060480)
1.3	3.8	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
1.3	2.5	GO:0031133	regulation of axon diameter(GO:0031133)
1.2	9.7	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
1.2	4.6	GO:0035720	intraciliary anterograde transport(GO:0035720)
1.1	4.6	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
1.1	3.3	GO:0036071	N-glycan fucosylation(GO:0036071)
1.1	3.2	GO:0060214	endocardium formation(GO:0060214)
1.1	14.8	GO:0035878	nail development(GO:0035878)
1.0	5.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.0	23.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
1.0	3.0	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.0	10.7	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
1.0	2.9	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
1.0	1.9	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
1.0	1.9	GO:0048263	determination of dorsal identity(GO:0048263)
1.0	3.8	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
0.9	7.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.9	9.3	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.9	8.4	GO:0006477	protein sulfation(GO:0006477)
0.9	70.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.9	3.7	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.9	3.6	GO:0072660	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9	8.2	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.9	5.4	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.9	3.5	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.8	8.5	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.8	3.4	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.8	3.4	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.8	3.3	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.8	46.3	GO:0048747	muscle fiber development(GO:0048747)
0.8	2.5	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.8	18.5	GO:0098743	cell aggregation(GO:0098743)
0.8	12.3	GO:0007097	nuclear migration(GO:0007097)
0.7	20.2	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.7	14.5	GO:0003334	keratinocyte development(GO:0003334)
0.7	5.8	GO:2001300	lipoxin metabolic process(GO:2001300)
0.7	12.9	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.7	4.3	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.7	2.8	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.7	5.6	GO:0007266	Rho protein signal transduction(GO:0007266)
0.7	4.8	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.7	2.0	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7	103.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.7	6.0	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.7	9.9	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.6	56.8	GO:0070527	platelet aggregation(GO:0070527)
0.6	10.0	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.6	1.9	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.6	1.8	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.6	1.2	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.6	1.7	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.5	2.7	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.5	2.1	GO:0023021	glucosylceramide catabolic process(GO:0006680) termination of signal transduction(GO:0023021) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.5	2.1	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
0.5	3.6	GO:0031642	negative regulation of myelination(GO:0031642)
0.5	10.3	GO:0003416	endochondral bone growth(GO:0003416)
0.5	3.0	GO:0060346	bone trabecula formation(GO:0060346)
0.5	9.8	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.5	12.2	GO:0060325	face morphogenesis(GO:0060325)
0.5	4.3	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.5	20.7	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.5	1.4	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.5	1.8	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.5	2.7	GO:0015811	L-cystine transport(GO:0015811)
0.5	5.0	GO:0008272	sulfate transport(GO:0008272)
0.5	2.3	GO:0030035	microspike assembly(GO:0030035)
0.4	4.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.4	6.7	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.4	3.5	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.4	5.7	GO:0006702	androgen biosynthetic process(GO:0006702)
0.4	9.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.4	48.0	GO:0030449	regulation of complement activation(GO:0030449)
0.4	5.5	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.4	2.5	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.4	3.5	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4	3.5	GO:0051451	myoblast migration(GO:0051451)
0.4	8.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.4	2.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.4	26.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.4	3.5	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.3	1.7	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.3	27.4	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.3	3.0	GO:0060242	contact inhibition(GO:0060242)
0.3	2.0	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3	1.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.3	1.9	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.3	3.7	GO:0015671	oxygen transport(GO:0015671)
0.3	2.6	GO:1905247	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3	25.9	GO:0070268	cornification(GO:0070268)
0.3	117.9	GO:0006936	muscle contraction(GO:0006936)
0.3	12.4	GO:0015701	bicarbonate transport(GO:0015701)
0.3	2.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.3	3.1	GO:0045475	locomotor rhythm(GO:0045475)
0.3	1.5	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2	1.7	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2	1.5	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.2	0.7	GO:0006711	estrogen catabolic process(GO:0006711)
0.2	0.7	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.2	3.1	GO:0051764	actin crosslink formation(GO:0051764)
0.2	2.1	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.2	21.8	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.2	26.0	GO:0021987	cerebral cortex development(GO:0021987)
0.2	1.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.2	0.9	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.2	5.6	GO:0006825	copper ion transport(GO:0006825)
0.2	4.5	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.2	4.2	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.2	13.5	GO:0042472	inner ear morphogenesis(GO:0042472)
0.2	2.6	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.2	2.6	GO:2000394	phosphatidylcholine catabolic process(GO:0034638) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2	21.7	GO:0051225	spindle assembly(GO:0051225)
0.2	23.5	GO:0000187	activation of MAPK activity(GO:0000187)
0.2	1.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.2	0.5	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.2	27.2	GO:0031032	actomyosin structure organization(GO:0031032)
0.2	15.1	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2	16.8	GO:0009062	fatty acid catabolic process(GO:0009062)
0.2	0.5	GO:0045112	integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.2	1.0	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.2	2.2	GO:0030220	platelet formation(GO:0030220)
0.2	2.5	GO:0006751	glutathione catabolic process(GO:0006751)
0.2	12.3	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.2	4.7	GO:0019433	triglyceride catabolic process(GO:0019433)
0.2	1.9	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2	5.7	GO:0046785	microtubule polymerization(GO:0046785)
0.2	5.6	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.2	31.4	GO:0006986	response to unfolded protein(GO:0006986)
0.2	6.2	GO:0008542	visual learning(GO:0008542)
0.1	0.7	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.1	1.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	2.4	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.5	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.1	5.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	2.5	GO:0031638	zymogen activation(GO:0031638)
0.1	4.0	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.1	0.8	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1	11.5	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1	1.3	GO:0042346	positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1	5.1	GO:0021549	cerebellum development(GO:0021549)
0.1	1.6	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1	1.2	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	1.8	GO:0016540	protein autoprocessing(GO:0016540)
0.1	10.7	GO:0002576	platelet degranulation(GO:0002576)
0.1	0.8	GO:0098719	gastric acid secretion(GO:0001696) sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1	1.4	GO:0070914	UV-damage excision repair(GO:0070914)
0.1	1.2	GO:0007605	sensory perception of sound(GO:0007605)
0.1	4.0	GO:0006749	glutathione metabolic process(GO:0006749)
0.1	0.8	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.9	GO:0061037	negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037)
0.1	2.0	GO:0015695	organic cation transport(GO:0015695)
0.1	1.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	3.3	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.1	0.1	GO:0070638	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1	8.8	GO:0001649	osteoblast differentiation(GO:0001649)
0.1	0.5	GO:0044245	polysaccharide digestion(GO:0044245)
0.1	5.3	GO:0098869	cellular oxidant detoxification(GO:0098869)
0.1	5.6	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	0.7	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.1	0.3	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1	1.0	GO:0030252	growth hormone secretion(GO:0030252)
0.1	0.7	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.7	GO:0030050	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1	1.6	GO:0007052	mitotic spindle organization(GO:0007052)
0.1	1.1	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	1.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.8	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	1.9	GO:0046847	filopodium assembly(GO:0046847)
0.0	1.5	GO:0051693	actin filament capping(GO:0051693)
0.0	2.7	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	3.5	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	2.8	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	2.6	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.9	GO:0051646	mitochondrion localization(GO:0051646)
0.0	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.0	1.6	GO:0030879	mammary gland development(GO:0030879)
0.0	0.1	GO:0044254	angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0	0.1	GO:2000510	positive regulation of sperm motility involved in capacitation(GO:0060474) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.7	GO:0006479	protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0	0.8	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	2.9	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
31.2	124.9	GO:0030485	smooth muscle contractile fiber(GO:0030485)
13.8	124.5	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
13.5	215.8	GO:0097512	cardiac myofibril(GO:0097512)
10.4	31.3	GO:0034680	integrin alpha3-beta1 complex(GO:0034667) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
6.9	90.0	GO:0005577	fibrinogen complex(GO:0005577)
6.5	97.9	GO:0030478	actin cap(GO:0030478)
6.3	31.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
6.2	31.0	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
6.2	24.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
6.1	18.2	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
5.7	80.0	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
5.5	16.5	GO:0005588	collagen type V trimer(GO:0005588)
3.8	64.2	GO:0032059	bleb(GO:0032059)
3.6	213.6	GO:0005801	cis-Golgi network(GO:0005801)
3.3	72.6	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
2.7	10.7	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
2.7	31.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
2.5	89.0	GO:0005859	muscle myosin complex(GO:0005859)
2.3	6.9	GO:0020005	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
2.2	19.7	GO:0099634	postsynaptic specialization membrane(GO:0099634)
2.0	9.9	GO:0060091	kinocilium(GO:0060091)
1.8	16.6	GO:0070652	HAUS complex(GO:0070652)
1.7	3.4	GO:1990584	cardiac Troponin complex(GO:1990584)
1.6	14.8	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
1.6	4.7	GO:0005607	laminin-2 complex(GO:0005607)
1.5	4.6	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.4	4.3	GO:0000806	Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124)
1.3	4.0	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
1.3	4.0	GO:0031523	Myb complex(GO:0031523)
1.2	5.9	GO:0071148	TEAD-1-YAP complex(GO:0071148)
1.1	12.0	GO:0002116	semaphorin receptor complex(GO:0002116)
1.0	14.8	GO:0030056	hemidesmosome(GO:0030056)
0.9	45.5	GO:0043034	costamere(GO:0043034)
0.8	12.3	GO:0005869	dynactin complex(GO:0005869)
0.8	8.8	GO:0005916	fascia adherens(GO:0005916)
0.8	3.1	GO:0016600	flotillin complex(GO:0016600)
0.7	22.7	GO:0009925	basal plasma membrane(GO:0009925)
0.7	4.8	GO:0001520	outer dense fiber(GO:0001520)
0.7	16.5	GO:0031143	pseudopodium(GO:0031143)
0.6	41.4	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.6	5.4	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.6	61.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.5	9.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.5	19.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.5	1.6	GO:0031262	Ndc80 complex(GO:0031262)
0.5	7.6	GO:0043234	protein complex(GO:0043234)
0.5	4.0	GO:0042788	polysomal ribosome(GO:0042788)
0.5	7.8	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.4	3.6	GO:0005610	laminin-5 complex(GO:0005610)
0.4	179.0	GO:0016324	apical plasma membrane(GO:0016324)
0.4	2.6	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.4	3.8	GO:0005579	membrane attack complex(GO:0005579)
0.4	2.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.4	36.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.4	75.5	GO:0072562	blood microparticle(GO:0072562)
0.4	20.0	GO:0016235	aggresome(GO:0016235)
0.4	6.2	GO:0005652	nuclear lamina(GO:0005652)
0.4	126.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.4	27.3	GO:0005811	lipid particle(GO:0005811)
0.3	14.5	GO:0002102	podosome(GO:0002102)
0.3	13.3	GO:0043198	dendritic shaft(GO:0043198)
0.3	29.1	GO:0030175	filopodium(GO:0030175)
0.3	15.1	GO:0005871	kinesin complex(GO:0005871)
0.3	2.1	GO:0033269	internode region of axon(GO:0033269)
0.3	2.0	GO:0097209	epidermal lamellar body(GO:0097209)
0.3	2.5	GO:0043083	synaptic cleft(GO:0043083)
0.3	15.0	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3	11.2	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.3	0.5	GO:0071437	invadopodium(GO:0071437) invadopodium membrane(GO:0071438)
0.2	20.5	GO:0005882	intermediate filament(GO:0005882)
0.2	21.0	GO:0032587	ruffle membrane(GO:0032587)
0.2	17.6	GO:0001750	photoreceptor outer segment(GO:0001750)
0.2	3.1	GO:0031941	filamentous actin(GO:0031941)
0.2	2.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	1.8	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2	1.8	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.2	12.4	GO:0072686	mitotic spindle(GO:0072686)
0.2	6.7	GO:0016459	myosin complex(GO:0016459)
0.2	6.6	GO:0001533	cornified envelope(GO:0001533)
0.2	1.4	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2	5.0	GO:0097542	ciliary tip(GO:0097542)
0.2	3.5	GO:0033268	node of Ranvier(GO:0033268)
0.2	10.2	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	0.9	GO:0097427	microtubule bundle(GO:0097427)
0.1	3.3	GO:0035869	ciliary transition zone(GO:0035869)
0.1	1.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	5.5	GO:0005581	collagen trimer(GO:0005581)
0.1	1.5	GO:0008091	spectrin(GO:0008091)
0.1	0.7	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	6.2	GO:0042641	actomyosin(GO:0042641)
0.1	1.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	4.5	GO:0030863	cortical cytoskeleton(GO:0030863)
0.1	3.7	GO:0036064	ciliary basal body(GO:0036064)
0.1	6.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	11.9	GO:0001650	fibrillar center(GO:0001650)
0.1	92.8	GO:0005783	endoplasmic reticulum(GO:0005783)
0.1	76.9	GO:0005615	extracellular space(GO:0005615)
0.1	1.1	GO:0042629	mast cell granule(GO:0042629)
0.1	0.9	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	11.2	GO:0005769	early endosome(GO:0005769)
0.0	1.3	GO:0045177	apical part of cell(GO:0045177)
0.0	2.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	6.9	GO:0005874	microtubule(GO:0005874)
0.0	10.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	1.3	GO:0044215	host(GO:0018995) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.4	GO:0005771	multivesicular body(GO:0005771)
0.0	1.5	GO:0005770	late endosome(GO:0005770)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.4	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.2	GO:0071004	U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
27.7	83.0	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
13.7	41.0	GO:0070052	collagen V binding(GO:0070052)
11.2	33.7	GO:0004924	oncostatin-M receptor activity(GO:0004924)
10.9	261.6	GO:0001968	fibronectin binding(GO:0001968)
7.8	31.3	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
7.6	38.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
6.4	196.9	GO:0005212	structural constituent of eye lens(GO:0005212)
6.1	18.2	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
5.8	127.1	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
5.2	31.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
4.9	136.3	GO:0005523	tropomyosin binding(GO:0005523)
3.2	13.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
3.1	96.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
2.9	46.4	GO:0032036	myosin heavy chain binding(GO:0032036)
2.9	11.4	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
2.7	26.9	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
2.6	18.4	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
2.5	20.3	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
2.5	10.0	GO:0038132	neuregulin binding(GO:0038132)
2.5	27.1	GO:0001042	RNA polymerase I core binding(GO:0001042)
2.5	54.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
2.3	6.9	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
2.0	7.8	GO:0042030	ATPase inhibitor activity(GO:0042030)
1.9	5.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
1.9	7.5	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
1.9	1.9	GO:0031432	titin binding(GO:0031432) RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.8	23.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
1.8	46.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
1.8	3.5	GO:0010465	nerve growth factor receptor activity(GO:0010465)
1.7	6.7	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
1.6	31.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
1.5	24.3	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
1.5	29.6	GO:0045295	gamma-catenin binding(GO:0045295)
1.5	30.7	GO:0035497	cAMP response element binding(GO:0035497)
1.4	5.8	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
1.4	36.5	GO:0030506	ankyrin binding(GO:0030506)
1.4	8.4	GO:0009378	four-way junction helicase activity(GO:0009378)
1.3	4.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
1.3	26.6	GO:0031005	filamin binding(GO:0031005)
1.3	14.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
1.2	96.1	GO:0008307	structural constituent of muscle(GO:0008307)
1.2	8.4	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.2	3.5	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.2	16.3	GO:0042043	neurexin family protein binding(GO:0042043)
1.1	9.9	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
1.1	3.3	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
1.1	3.3	GO:0042015	interleukin-20 binding(GO:0042015)
1.1	5.4	GO:0017018	myosin phosphatase activity(GO:0017018)
1.0	19.7	GO:0033130	acetylcholine receptor binding(GO:0033130) protein anchor(GO:0043495)
1.0	4.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
1.0	3.0	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.0	50.6	GO:0016504	peptidase activator activity(GO:0016504)
1.0	38.1	GO:0001972	retinoic acid binding(GO:0001972)
1.0	23.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.9	9.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.9	7.1	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.9	20.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.9	3.5	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.8	3.4	GO:0047708	biotinidase activity(GO:0047708)
0.8	15.7	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.8	2.5	GO:0015403	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.8	4.0	GO:0034046	poly(G) binding(GO:0034046)
0.8	72.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.7	5.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.7	5.7	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.7	7.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.7	4.6	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.6	2.6	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.6	10.9	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	5.0	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.6	5.6	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6	3.6	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.6	7.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.5	6.0	GO:0008432	JUN kinase binding(GO:0008432)
0.5	5.3	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5	2.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.5	32.4	GO:0017022	myosin binding(GO:0017022)
0.5	6.3	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.5	2.7	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.4	1.7	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4	3.4	GO:0031014	troponin T binding(GO:0031014)
0.4	1.7	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.4	12.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.4	2.4	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.4	34.7	GO:0032947	protein complex scaffold(GO:0032947)
0.3	1.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.3	8.7	GO:0042169	SH2 domain binding(GO:0042169)
0.3	2.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3	2.2	GO:0030332	cyclin binding(GO:0030332)
0.3	5.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3	32.9	GO:0019838	growth factor binding(GO:0019838)
0.3	6.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3	1.8	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	3.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.3	34.4	GO:0051219	phosphoprotein binding(GO:0051219)
0.3	5.5	GO:0005537	mannose binding(GO:0005537)
0.3	3.7	GO:0005344	oxygen transporter activity(GO:0005344)
0.3	5.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.3	3.0	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3	4.3	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.3	0.5	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.3	2.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.3	2.0	GO:0031433	telethonin binding(GO:0031433)
0.2	36.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.2	10.7	GO:0005504	fatty acid binding(GO:0005504)
0.2	11.2	GO:0008009	chemokine activity(GO:0008009)
0.2	7.5	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.2	22.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.2	9.9	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2	175.8	GO:0005509	calcium ion binding(GO:0005509)
0.2	12.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2	0.9	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	5.0	GO:0070064	proline-rich region binding(GO:0070064)
0.2	4.7	GO:0004806	triglyceride lipase activity(GO:0004806)
0.2	5.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	11.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.2	2.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	12.4	GO:0019003	GDP binding(GO:0019003)
0.2	0.8	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2	5.2	GO:0019894	kinesin binding(GO:0019894)
0.2	5.6	GO:0008013	beta-catenin binding(GO:0008013)
0.2	13.7	GO:0003777	microtubule motor activity(GO:0003777)
0.2	0.5	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.2	1.9	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.2	2.0	GO:0017166	vinculin binding(GO:0017166)
0.2	4.3	GO:0035173	histone kinase activity(GO:0035173)
0.2	2.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	1.6	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	12.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	1.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	0.7	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	2.8	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	41.8	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1	6.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	31.0	GO:0003924	GTPase activity(GO:0003924)
0.1	3.6	GO:0030507	spectrin binding(GO:0030507)
0.1	17.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	13.7	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.1	3.8	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	11.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	3.3	GO:0030165	PDZ domain binding(GO:0030165)
0.1	4.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	1.2	GO:0005112	Notch binding(GO:0005112)
0.1	5.6	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	0.7	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1	0.4	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.8	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.1	0.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	3.9	GO:0097110	scaffold protein binding(GO:0097110)
0.1	2.1	GO:0030515	snoRNA binding(GO:0030515)
0.1	13.7	GO:0008017	microtubule binding(GO:0008017)
0.1	4.8	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	2.5	GO:0043621	protein self-association(GO:0043621)
0.1	7.9	GO:0005179	hormone activity(GO:0005179)
0.1	1.1	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	1.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	1.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	2.1	GO:0005507	copper ion binding(GO:0005507)
0.1	2.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.1	2.8	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	10.4	GO:0005198	structural molecule activity(GO:0005198)
0.0	1.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	1.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	1.6	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.9	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.5	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	6.6	GO:0000287	magnesium ion binding(GO:0000287)
0.0	2.4	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	4.8	GO:0030246	carbohydrate binding(GO:0030246)
0.0	1.7	GO:0051087	chaperone binding(GO:0051087)
0.0	0.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	2.8	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	2.1	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	1.2	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.6	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	1.4	GO:0047485	protein N-terminus binding(GO:0047485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.0	149.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
4.1	397.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
2.0	116.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.4	23.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.1	39.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.1	4.6	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.9	21.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.9	12.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.9	42.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.8	30.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.8	63.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.7	25.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.7	40.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.7	56.8	PID NOTCH PATHWAY	Notch signaling pathway
0.6	9.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.6	115.6	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.6	26.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.6	6.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.5	9.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.5	17.6	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.5	43.3	PID AP1 PATHWAY	AP-1 transcription factor network
0.4	8.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.4	16.0	NABA COLLAGENS	Genes encoding collagen proteins
0.4	11.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.4	18.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3	8.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.3	4.3	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.3	49.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	4.6	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.3	5.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.2	9.1	PID ARF6 PATHWAY	Arf6 signaling events
0.2	7.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2	5.1	PID ARF 3PATHWAY	Arf1 pathway
0.2	13.3	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.2	4.0	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	7.5	PID FGF PATHWAY	FGF signaling pathway
0.2	6.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.2	5.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	4.2	PID CDC42 PATHWAY	CDC42 signaling events
0.2	4.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	5.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.2	31.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	1.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.2	7.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.7	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	0.6	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	0.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	17.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	2.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	1.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	2.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	15.0	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	2.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.0	265.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
6.9	124.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
5.7	362.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
4.1	119.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
3.5	38.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
2.5	61.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
2.3	64.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
2.3	55.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
1.5	31.9	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
1.3	32.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
1.3	23.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
1.3	37.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.2	22.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.0	26.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.9	23.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.8	20.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.7	10.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.7	25.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.7	17.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.5	26.6	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.5	5.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.5	11.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.5	7.4	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.5	6.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.4	15.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.4	5.7	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.4	44.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.4	9.9	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3	8.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.3	4.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3	8.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.3	7.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.3	32.6	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.3	8.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	6.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	16.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	10.7	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.2	13.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	6.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2	11.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	2.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.2	3.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.2	15.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	9.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	4.9	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	0.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	5.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	2.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	1.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	4.3	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	6.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.9	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	1.2	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.1	9.1	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	5.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	2.8	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.4	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	0.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	2.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.5	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	3.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	1.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.8	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor

Results for TEAD3_TEAD1

Z-value: 3.38

Motif logo

Transcription factors associated with TEAD3_TEAD1

Activity-expression correlation:

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: