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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TFAP4_MSC

Z-value: 1.33

Motif logo

Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
ENSG00000090447.7 transcription factor AP-4
ENSG00000178860.8 musculin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP4hg19_v2_chr16_-_4323015_43230760.161.5e-02Click!
MSChg19_v2_chr8_-_72756667_727567360.054.7e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_123752624 24.95 ENST00000542174.1
ENST00000535796.1
cyclin-dependent kinase 2 associated protein 1
chr11_-_111783595 24.16 ENST00000528628.1
crystallin, alpha B
chr1_+_10271674 20.91 ENST00000377086.1
kinesin family member 1B
chr7_-_30029574 19.45 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
secernin 1
chr7_-_30029367 18.87 ENST00000242059.5
secernin 1
chr5_+_102201722 18.74 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chr16_-_21289627 17.74 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr5_+_102201509 17.29 ENST00000348126.2
ENST00000379787.4
peptidylglycine alpha-amidating monooxygenase
chr19_+_18208603 14.64 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr18_-_74728998 14.05 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr15_-_42749711 13.82 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr5_-_16936340 13.58 ENST00000507288.1
ENST00000513610.1
myosin X
chr2_+_54198210 12.90 ENST00000607452.1
ENST00000422521.2
acylphosphatase 2, muscle type
chr14_+_90863327 12.45 ENST00000356978.4
calmodulin 1 (phosphorylase kinase, delta)
chr5_+_102201430 12.15 ENST00000438793.3
ENST00000346918.2
peptidylglycine alpha-amidating monooxygenase
chr5_+_102201687 11.54 ENST00000304400.7
peptidylglycine alpha-amidating monooxygenase
chr3_+_159570722 11.38 ENST00000482804.1
schwannomin interacting protein 1
chr12_+_56473628 11.03 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_-_117748138 10.81 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr11_-_117747607 10.79 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr6_+_30851840 10.67 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
discoidin domain receptor tyrosine kinase 1
chr11_-_117747434 10.64 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr1_+_153600869 10.50 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100 calcium binding protein A1
chr3_-_178790057 10.43 ENST00000311417.2
zinc finger, matrin-type 3
chr3_-_33700933 10.02 ENST00000480013.1
cytoplasmic linker associated protein 2
chr1_-_86043921 9.93 ENST00000535924.2
dimethylarginine dimethylaminohydrolase 1
chr6_+_30852130 9.57 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
discoidin domain receptor tyrosine kinase 1
chr21_-_27542972 9.37 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
amyloid beta (A4) precursor protein
chr3_-_33700589 9.30 ENST00000461133.3
ENST00000496954.2
cytoplasmic linker associated protein 2
chr8_-_110660999 9.24 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
syntabulin (syntaxin-interacting)
chr10_-_97321165 9.10 ENST00000306402.6
sorbin and SH3 domain containing 1
chr2_-_225811747 8.17 ENST00000409592.3
dedicator of cytokinesis 10
chr3_+_167453493 8.15 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr11_-_66725837 8.10 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr14_-_67826486 8.00 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr15_+_42696954 7.63 ENST00000337571.4
ENST00000569136.1
calpain 3, (p94)
chr15_+_42696992 7.48 ENST00000561817.1
calpain 3, (p94)
chr15_+_42697018 7.38 ENST00000397204.4
calpain 3, (p94)
chr12_-_50297638 7.20 ENST00000320634.3
Fas apoptotic inhibitory molecule 2
chr12_-_50298000 7.19 ENST00000550635.2
Fas apoptotic inhibitory molecule 2
chr1_-_150669604 6.95 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr4_-_90759440 6.82 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_153303658 6.55 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr8_+_9413410 6.37 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr21_-_27543425 6.31 ENST00000448388.2
amyloid beta (A4) precursor protein
chr15_+_42697065 6.28 ENST00000565559.1
calpain 3, (p94)
chr10_-_73611046 6.10 ENST00000394934.1
ENST00000394936.3
prosaposin
chr5_-_11589131 6.07 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr19_-_34012674 5.80 ENST00000436370.3
ENST00000397032.4
ENST00000244137.7
peptidase D
chr2_+_11752379 5.76 ENST00000396123.1
growth regulation by estrogen in breast cancer 1
chr2_-_183903133 5.69 ENST00000361354.4
NCK-associated protein 1
chr12_-_120315074 5.62 ENST00000261833.7
ENST00000392521.2
citron (rho-interacting, serine/threonine kinase 21)
chr22_+_38071615 5.44 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr8_-_49834299 5.43 ENST00000396822.1
snail family zinc finger 2
chr11_+_62475130 5.39 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr10_+_13142225 5.39 ENST00000378747.3
optineurin
chr3_+_69134124 5.32 ENST00000478935.1
ADP-ribosylation-like factor 6 interacting protein 5
chr2_-_176866978 5.31 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr3_+_69134080 5.26 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr1_-_175712829 5.22 ENST00000367674.2
tenascin R
chr11_-_62474803 5.19 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_-_62149433 5.17 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_69942298 5.15 ENST00000238918.8
brain-specific angiogenesis inhibitor 3
chr10_+_13142075 5.14 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr8_-_13134045 5.10 ENST00000512044.2
deleted in liver cancer 1
chr1_+_51701924 5.05 ENST00000242719.3
ring finger protein 11
chr8_-_30670053 4.97 ENST00000518564.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr12_+_12938541 4.97 ENST00000356591.4
apolipoprotein L domain containing 1
chr2_-_74607390 4.93 ENST00000413111.1
ENST00000409567.3
ENST00000454119.1
ENST00000361874.3
ENST00000394003.3
dynactin 1
chr19_+_35521572 4.91 ENST00000262631.5
sodium channel, voltage-gated, type I, beta subunit
chr3_+_32147997 4.90 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr1_+_15272271 4.88 ENST00000400797.3
kazrin, periplakin interacting protein
chr17_-_73851285 4.86 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chr10_+_1102721 4.76 ENST00000263150.4
WD repeat domain 37
chr10_-_97321112 4.74 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
sorbin and SH3 domain containing 1
chr8_-_49833978 4.53 ENST00000020945.1
snail family zinc finger 2
chr15_-_83240507 4.47 ENST00000564522.1
ENST00000398592.2
cytoplasmic polyadenylation element binding protein 1
chr4_-_46391805 4.43 ENST00000540012.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr6_-_128841503 4.43 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr6_+_150070831 4.39 ENST00000367380.5
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr10_-_73848764 4.31 ENST00000317376.4
ENST00000412663.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr16_-_31106211 4.29 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr16_-_67514982 4.23 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr2_+_136343820 4.21 ENST00000410054.1
R3H domain containing 1
chr18_+_54318616 4.07 ENST00000254442.3
WD repeat domain 7
chr19_+_35521616 4.06 ENST00000595652.1
sodium channel, voltage-gated, type I, beta subunit
chr10_+_88428206 4.06 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chrX_-_10851762 4.05 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr18_-_5419797 4.03 ENST00000542146.1
ENST00000427684.2
erythrocyte membrane protein band 4.1-like 3
chr11_-_1330834 3.98 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
toll interacting protein
chrX_-_137793826 3.96 ENST00000315930.6
fibroblast growth factor 13
chr4_+_114214125 3.95 ENST00000509550.1
ankyrin 2, neuronal
chr7_+_48128816 3.91 ENST00000395564.4
uridine phosphorylase 1
chr4_-_46391367 3.84 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr15_+_63354769 3.80 ENST00000558910.1
tropomyosin 1 (alpha)
chr10_+_102790980 3.73 ENST00000393459.1
ENST00000224807.5
sideroflexin 3
chr7_+_48128194 3.69 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
uridine phosphorylase 1
chr4_-_52904425 3.67 ENST00000535450.1
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr17_-_1090599 3.67 ENST00000544583.2
active BCR-related
chr8_+_98788003 3.65 ENST00000521545.2
lysosomal protein transmembrane 4 beta
chr7_+_48128854 3.64 ENST00000436673.1
ENST00000429491.2
uridine phosphorylase 1
chr7_-_100065686 3.56 ENST00000423266.1
ENST00000456330.1
TSC22 domain family, member 4
chr7_+_48128316 3.54 ENST00000341253.4
uridine phosphorylase 1
chr8_-_72274467 3.42 ENST00000340726.3
eyes absent homolog 1 (Drosophila)
chr4_+_154178520 3.41 ENST00000433687.1
tripartite motif containing 2
chr3_-_52001448 3.39 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr6_-_132834184 3.39 ENST00000367941.2
ENST00000367937.4
syntaxin 7
chr20_+_62697564 3.38 ENST00000458442.1
transcription elongation factor A (SII), 2
chrX_+_135278908 3.37 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr12_-_54121212 3.30 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
calcium binding and coiled-coil domain 1
chr11_+_45918092 3.24 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr17_+_3379284 3.19 ENST00000263080.2
aspartoacylase
chr16_-_31106048 3.17 ENST00000300851.6
vitamin K epoxide reductase complex, subunit 1
chr3_+_35721106 3.16 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr1_+_200708671 3.14 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr16_-_5147743 3.14 ENST00000587133.1
ENST00000458008.4
ENST00000427587.4
family with sequence similarity 86, member A
chr19_+_36249057 3.10 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
chromosome 19 open reading frame 55
chr4_+_7045042 3.08 ENST00000310074.7
ENST00000512388.1
transcriptional adaptor 2B
chr15_-_72523924 3.05 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
pyruvate kinase, muscle
chrX_-_9734004 3.05 ENST00000467482.1
ENST00000380929.2
G protein-coupled receptor 143
chr12_-_54121261 3.04 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr16_+_23652773 2.88 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
dynactin 5 (p25)
chr7_-_104909435 2.85 ENST00000357311.3
SRSF protein kinase 2
chr11_+_61722629 2.81 ENST00000526988.1
bestrophin 1
chr11_+_71498552 2.77 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
family with sequence similarity 86, member C1
chr19_-_48018203 2.76 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr8_+_104033296 2.75 ENST00000521514.1
ENST00000518738.1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr8_-_30670384 2.75 ENST00000221138.4
ENST00000518243.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr22_+_19705928 2.74 ENST00000383045.3
ENST00000438754.2
septin 5
chr11_-_796197 2.73 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr7_+_99699280 2.64 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr9_+_99212403 2.62 ENST00000375251.3
ENST00000375249.4
hyaluronan binding protein 4
chr1_-_182360498 2.56 ENST00000417584.2
glutamate-ammonia ligase
chr6_+_150070857 2.52 ENST00000544496.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_+_99699179 2.49 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr17_-_41174424 2.43 ENST00000355653.3
vesicle amine transport 1
chr17_-_7145106 2.40 ENST00000577035.1
GABA(A) receptor-associated protein
chr12_-_49525175 2.39 ENST00000336023.5
ENST00000550367.1
ENST00000552984.1
ENST00000547476.1
tubulin, alpha 1b
chr20_+_53092123 2.39 ENST00000262593.5
docking protein 5
chr12_-_56122426 2.37 ENST00000551173.1
CD63 molecule
chr11_-_1587166 2.36 ENST00000331588.4
dual specificity phosphatase 8
chr7_-_82792215 2.36 ENST00000333891.9
ENST00000423517.2
piccolo presynaptic cytomatrix protein
chr17_+_57232690 2.35 ENST00000262293.4
proline rich 11
chr3_-_183273477 2.33 ENST00000341319.3
kelch-like family member 6
chr8_-_57358432 2.28 ENST00000517415.1
ENST00000314922.3
proenkephalin
chr6_+_110012462 2.27 ENST00000441478.2
ENST00000230124.3
FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
chr3_-_15106747 2.26 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
mitochondrial ribosomal protein S25
chr12_-_30887948 2.26 ENST00000433722.2
caprin family member 2
chr20_-_44485835 2.25 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
acyl-CoA thioesterase 8
chr3_-_50360192 2.22 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
hyaluronoglucosaminidase 2
chr7_-_108166505 2.21 ENST00000426128.2
ENST00000427008.1
ENST00000388728.5
ENST00000257694.8
ENST00000422087.1
ENST00000453144.1
ENST00000436062.1
patatin-like phospholipase domain containing 8
chr14_+_45431379 2.20 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
family with sequence similarity 179, member B
chr5_+_113697983 2.20 ENST00000264773.3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr16_+_66914264 2.19 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr12_+_69201923 2.16 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chrX_+_128872998 2.15 ENST00000371106.3
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr9_-_35111420 2.14 ENST00000378557.1
family with sequence similarity 214, member B
chr19_+_10527449 2.12 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr19_+_16830774 2.11 ENST00000524140.2
NACHT and WD repeat domain containing 1
chr1_+_155051305 2.10 ENST00000368408.3
ephrin-A3
chr11_+_32112431 2.10 ENST00000054950.3
reticulocalbin 1, EF-hand calcium binding domain
chr12_-_50677255 2.09 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr1_-_165414414 2.08 ENST00000359842.5
retinoid X receptor, gamma
chr16_+_83932684 2.07 ENST00000262430.4
malonyl-CoA decarboxylase
chr15_-_83680325 2.07 ENST00000508990.2
ENST00000510873.2
ENST00000538348.2
ENST00000451195.3
ENST00000513601.2
ENST00000304177.5
ENST00000565712.1
chromosome 15 open reading frame 40
chr1_-_85462623 2.06 ENST00000370608.3
mucolipin 2
chr2_+_192110199 2.01 ENST00000304164.4
myosin IB
chr9_+_17134980 2.01 ENST00000380647.3
centlein, centrosomal protein
chr4_-_186125077 1.98 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
chr17_-_47755338 1.98 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
speckle-type POZ protein
chrX_+_21857764 1.97 ENST00000365779.2
membrane-bound transcription factor peptidase, site 2
chr17_+_68071458 1.94 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_-_136288113 1.94 ENST00000401392.1
zinc finger, RAN-binding domain containing 3
chr6_-_34524049 1.92 ENST00000374037.3
SAM pointed domain containing ETS transcription factor
chr8_-_72274095 1.89 ENST00000303824.7
eyes absent homolog 1 (Drosophila)
chr17_+_7461849 1.89 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chr3_+_49058444 1.88 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr10_-_73848531 1.87 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_-_69870747 1.86 ENST00000409068.1
AP2 associated kinase 1
chr15_+_43809797 1.86 ENST00000399453.1
ENST00000300231.5
microtubule-associated protein 1A
chr5_+_54455946 1.86 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr19_-_2151523 1.85 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
adaptor-related protein complex 3, delta 1 subunit
chr8_+_104033277 1.85 ENST00000518857.1
ENST00000395862.3
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr3_-_69435224 1.81 ENST00000398540.3
FERM domain containing 4B
chr12_+_122150646 1.80 ENST00000449592.2
transmembrane protein 120B
chr6_+_96463840 1.79 ENST00000302103.5
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr5_+_95066823 1.78 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr3_+_49507559 1.77 ENST00000421560.1
ENST00000308775.2
ENST00000545947.1
ENST00000541308.1
ENST00000539901.1
ENST00000538711.1
ENST00000418588.1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr8_+_107738240 1.77 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chrX_-_30326445 1.75 ENST00000378963.1
nuclear receptor subfamily 0, group B, member 1
chr19_-_59070239 1.75 ENST00000595957.1
ENST00000253023.3
ubiquitin-conjugating enzyme E2M
chr18_+_55816546 1.71 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_-_1785139 1.71 ENST00000236671.2
cathepsin D
chr17_+_7482785 1.69 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68 molecule
chr11_-_47270341 1.68 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
acid phosphatase 2, lysosomal
chr21_+_34398153 1.67 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
oligodendrocyte lineage transcription factor 2
chr6_-_34524093 1.65 ENST00000544425.1
SAM pointed domain containing ETS transcription factor
chr8_+_124428959 1.62 ENST00000287387.2
ENST00000523984.1
WDYHV motif containing 1
chr3_+_132136331 1.60 ENST00000260818.6
DnaJ (Hsp40) homolog, subfamily C, member 13
chr1_+_19638788 1.59 ENST00000375155.3
ENST00000375153.3
ENST00000400548.2
PQ loop repeat containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 59.7 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
7.0 20.9 GO:1904647 response to rotenone(GO:1904647)
4.8 28.8 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
3.7 14.8 GO:0006218 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
3.3 10.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
3.1 15.7 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
3.0 9.0 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
2.8 14.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
2.7 8.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
2.4 19.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
2.2 20.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
2.1 6.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.6 17.7 GO:0006554 lysine catabolic process(GO:0006554)
1.5 1.5 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
1.4 6.8 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.4 5.4 GO:0002317 plasma cell differentiation(GO:0002317)
1.3 24.2 GO:0007021 tubulin complex assembly(GO:0007021)
1.3 10.6 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.3 4.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.3 10.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.3 6.5 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.3 5.2 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.2 4.9 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
1.2 4.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.2 3.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.1 3.2 GO:0006533 aspartate catabolic process(GO:0006533)
1.0 14.4 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.0 11.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.9 8.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.8 4.0 GO:1990834 response to odorant(GO:1990834)
0.8 0.8 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.8 6.9 GO:0030091 protein repair(GO:0030091)
0.8 9.9 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.7 2.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.7 4.9 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.6 2.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.6 4.9 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.6 3.1 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.6 5.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.6 4.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.6 2.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.6 5.7 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.6 4.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.6 1.7 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.6 2.2 GO:0019087 transformation of host cell by virus(GO:0019087)
0.6 11.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 1.6 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.5 3.6 GO:0010454 negative regulation of cell fate commitment(GO:0010454) lung goblet cell differentiation(GO:0060480)
0.5 2.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.5 3.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 2.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.5 3.8 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.5 12.7 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.5 15.8 GO:0090383 phagosome acidification(GO:0090383)
0.5 2.8 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.5 1.4 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.4 2.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 1.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.4 26.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.4 2.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.4 5.0 GO:0042118 endothelial cell activation(GO:0042118)
0.4 3.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 1.6 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.4 2.7 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.4 1.9 GO:0048478 replication fork protection(GO:0048478)
0.4 1.2 GO:0030575 nuclear body organization(GO:0030575)
0.4 3.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.4 4.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 1.7 GO:0035063 nuclear speck organization(GO:0035063)
0.3 5.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 3.7 GO:0055072 iron ion homeostasis(GO:0055072)
0.3 2.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 3.7 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.3 6.1 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.3 1.2 GO:0007525 somatic muscle development(GO:0007525)
0.3 3.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 2.4 GO:0030578 PML body organization(GO:0030578)
0.3 6.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 3.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 1.2 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.3 1.1 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.3 0.6 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 3.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.3 0.8 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.3 2.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 5.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 0.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 4.0 GO:0036010 protein localization to endosome(GO:0036010)
0.2 1.4 GO:0023021 termination of signal transduction(GO:0023021)
0.2 1.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 14.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 2.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.8 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 2.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 5.2 GO:0034389 lipid particle organization(GO:0034389)
0.2 2.8 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 2.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 2.2 GO:0016559 peroxisome fission(GO:0016559)
0.2 1.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 2.1 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 2.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 1.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 1.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 2.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 0.7 GO:0019086 late viral transcription(GO:0019086)
0.2 2.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 2.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 4.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 1.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.1 GO:1905146 lysosomal lumen acidification(GO:0007042) lysosomal protein catabolic process(GO:1905146)
0.2 0.9 GO:0015811 L-cystine transport(GO:0015811)
0.2 1.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.4 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 1.0 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 1.8 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 3.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.1 6.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 2.3 GO:0002467 germinal center formation(GO:0002467)
0.1 2.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 8.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 2.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1 1.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 2.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.5 GO:0070253 somatostatin secretion(GO:0070253) oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 3.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 3.2 GO:0010107 potassium ion import(GO:0010107)
0.1 4.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.6 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 1.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.6 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 1.7 GO:0045116 protein neddylation(GO:0045116)
0.1 6.0 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.5 GO:0033572 transferrin transport(GO:0033572)
0.1 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 10.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 7.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 10.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.3 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 2.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 3.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 3.7 GO:0045214 sarcomere organization(GO:0045214)
0.1 3.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 12.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 1.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 5.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 2.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 1.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 3.3 GO:0035418 protein localization to synapse(GO:0035418)
0.1 0.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 3.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 5.4 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.7 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.2 GO:0061743 motor learning(GO:0061743)
0.1 0.8 GO:0051775 response to redox state(GO:0051775)
0.1 1.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 1.8 GO:0007050 cell cycle arrest(GO:0007050)
0.1 1.0 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 4.6 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 5.4 GO:0070268 cornification(GO:0070268)
0.0 1.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 2.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.7 GO:0060177 regulation of angiotensin levels in blood(GO:0002002) angiotensin maturation(GO:0002003) regulation of angiotensin metabolic process(GO:0060177)
0.0 0.9 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 4.4 GO:0007030 Golgi organization(GO:0007030)
0.0 1.2 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 6.3 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.9 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 2.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 3.0 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 1.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.5 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 13.8 GO:0005899 insulin receptor complex(GO:0005899)
2.0 14.1 GO:0033269 internode region of axon(GO:0033269)
1.9 19.3 GO:0045180 basal cortex(GO:0045180)
1.7 15.7 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
1.5 24.2 GO:0097512 cardiac myofibril(GO:0097512)
1.0 3.1 GO:0072534 perineuronal net(GO:0072534)
0.9 6.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9 4.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.9 5.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.8 4.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.8 4.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.8 4.8 GO:0070545 PeBoW complex(GO:0070545)
0.8 13.6 GO:0032433 filopodium tip(GO:0032433)
0.7 9.2 GO:0097433 dense body(GO:0097433)
0.7 2.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.6 3.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.6 47.5 GO:0030315 T-tubule(GO:0030315)
0.5 8.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 4.8 GO:0016011 dystroglycan complex(GO:0016011)
0.5 3.2 GO:0044294 dendritic growth cone(GO:0044294)
0.5 1.4 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.5 12.3 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.4 5.7 GO:0031209 SCAR complex(GO:0031209)
0.4 64.4 GO:0043204 perikaryon(GO:0043204)
0.4 2.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 22.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 18.1 GO:1904115 axon cytoplasm(GO:1904115)
0.4 4.0 GO:0033270 paranode region of axon(GO:0033270)
0.4 5.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 4.9 GO:0005869 dynactin complex(GO:0005869)
0.3 2.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.3 6.9 GO:0031143 pseudopodium(GO:0031143)
0.3 4.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 1.9 GO:0043596 nuclear replication fork(GO:0043596)
0.2 0.7 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.6 GO:0071203 WASH complex(GO:0071203)
0.2 7.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.8 GO:0032059 bleb(GO:0032059)
0.2 7.9 GO:0031430 M band(GO:0031430)
0.2 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 7.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 4.9 GO:0030057 desmosome(GO:0030057)
0.2 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 3.1 GO:0030914 STAGA complex(GO:0030914)
0.2 13.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.7 GO:1990752 microtubule end(GO:1990752)
0.1 1.3 GO:0032009 early phagosome(GO:0032009)
0.1 2.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 2.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 14.5 GO:0005776 autophagosome(GO:0005776)
0.1 7.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 5.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 3.4 GO:0031201 SNARE complex(GO:0031201)
0.1 2.4 GO:0099738 cell cortex region(GO:0099738)
0.1 11.2 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.9 GO:0005883 neurofilament(GO:0005883)
0.1 6.3 GO:0043195 terminal bouton(GO:0043195)
0.1 1.4 GO:0042599 lamellar body(GO:0042599)
0.1 28.0 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.1 GO:0071011 U5 snRNP(GO:0005682) precatalytic spliceosome(GO:0071011)
0.1 11.7 GO:0043197 dendritic spine(GO:0043197)
0.1 3.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 5.5 GO:0005901 caveola(GO:0005901)
0.1 4.4 GO:0005811 lipid particle(GO:0005811)
0.1 4.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 27.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 4.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.1 GO:0045178 basal part of cell(GO:0045178)
0.0 5.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 9.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 14.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 3.1 GO:0043209 myelin sheath(GO:0043209)
0.0 2.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 3.4 GO:0030424 axon(GO:0030424)
0.0 0.6 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.9 GO:0030133 transport vesicle(GO:0030133)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.9 GO:0031968 organelle outer membrane(GO:0031968)
0.0 5.9 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 1.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.5 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.9 59.7 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
4.4 17.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
4.0 20.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
3.7 14.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
3.0 9.0 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.2 8.7 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.1 12.9 GO:0003998 acylphosphatase activity(GO:0003998)
2.0 28.2 GO:0031432 titin binding(GO:0031432)
2.0 6.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.8 5.4 GO:0048030 disaccharide binding(GO:0048030)
1.7 43.9 GO:0016805 dipeptidase activity(GO:0016805)
1.5 13.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.4 6.8 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.3 4.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.3 7.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.2 12.5 GO:0051425 PTB domain binding(GO:0051425)
1.2 14.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.9 20.5 GO:0002162 dystroglycan binding(GO:0002162)
0.8 11.0 GO:0038132 neuregulin binding(GO:0038132)
0.8 6.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.8 41.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.8 8.1 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.8 23.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.8 3.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 6.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.7 2.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.7 25.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.7 33.4 GO:0019894 kinesin binding(GO:0019894)
0.6 2.6 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.6 8.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.6 12.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.6 1.2 GO:0070097 delta-catenin binding(GO:0070097)
0.6 2.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 2.2 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.5 1.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.5 2.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.5 3.2 GO:0004046 aminoacylase activity(GO:0004046)
0.5 1.4 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.5 9.5 GO:0044548 S100 protein binding(GO:0044548)
0.4 1.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 4.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.4 2.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 2.0 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.3 2.3 GO:0001515 opioid peptide activity(GO:0001515)
0.3 6.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 3.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.3 5.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 5.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3 4.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 14.6 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 6.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 2.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 3.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 0.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 1.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 4.9 GO:0070840 dynein complex binding(GO:0070840)
0.2 1.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 2.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 1.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 2.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 3.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 1.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.8 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 26.3 GO:0044325 ion channel binding(GO:0044325)
0.2 1.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 2.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.9 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 2.4 GO:0005522 profilin binding(GO:0005522)
0.1 10.8 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 6.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 11.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 3.6 GO:0030552 cAMP binding(GO:0030552)
0.1 1.2 GO:0035240 dopamine binding(GO:0035240)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 7.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0032183 SUMO binding(GO:0032183)
0.1 1.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 8.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 7.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.3 GO:0005272 sodium channel activity(GO:0005272)
0.1 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 2.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842) ubiquitin-like protein transferase activity(GO:0019787)
0.0 4.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 2.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 2.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0003774 motor activity(GO:0003774)
0.0 1.1 GO:0042287 MHC protein binding(GO:0042287)
0.0 2.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 2.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.3 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 38.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.4 11.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.3 15.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.3 13.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 13.8 PID INSULIN PATHWAY Insulin Pathway
0.2 7.0 PID RAS PATHWAY Regulation of Ras family activation
0.2 8.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 7.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 3.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 6.6 PID AURORA A PATHWAY Aurora A signaling
0.2 6.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 7.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 9.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 5.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 4.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 6.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 4.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 5.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 3.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 14.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.8 15.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 8.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.5 15.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 12.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.5 7.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.4 11.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4 12.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 16.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 1.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 2.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 13.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 3.5 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.2 9.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 6.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 6.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 2.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 4.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 5.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 8.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 6.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 4.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 9.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 5.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 4.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions