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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TFDP1

Z-value: 2.64

Motif logo

Transcription factors associated with TFDP1

Gene Symbol Gene ID Gene Info
ENSG00000198176.8 transcription factor Dp-1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFDP1hg19_v2_chr13_+_114238997_1142390770.646.3e-27Click!

Activity profile of TFDP1 motif

Sorted Z-values of TFDP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_27022839 87.07 ENST00000457599.2
AT rich interactive domain 1A (SWI-like)
chr6_-_86352982 79.95 ENST00000369622.3
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_73179046 59.63 ENST00000314523.7
ENST00000420826.2
small ubiquitin-like modifier 2
chr11_+_85955787 53.05 ENST00000528180.1
embryonic ectoderm development
chr17_-_73178599 50.79 ENST00000578238.1
small ubiquitin-like modifier 2
chrX_-_16887963 47.90 ENST00000380084.4
retinoblastoma binding protein 7
chr1_+_43148625 47.83 ENST00000436427.1
Y box binding protein 1
chr17_+_34900737 47.45 ENST00000304718.4
ENST00000485685.2
gametogenetin binding protein 2
chrX_+_64887512 44.74 ENST00000360270.5
moesin
chr1_+_62902308 43.59 ENST00000339950.4
ubiquitin specific peptidase 1
chr1_+_29063119 42.34 ENST00000474884.1
ENST00000542507.1
YTH domain family, member 2
chr1_+_26798955 41.94 ENST00000361427.5
high mobility group nucleosomal binding domain 2
chr1_+_29063439 41.10 ENST00000541996.1
ENST00000496288.1
YTH domain family, member 2
chr4_-_83350580 40.90 ENST00000349655.4
ENST00000602300.1
heterogeneous nuclear ribonucleoprotein D-like
chr17_+_37026106 40.78 ENST00000318008.6
LIM and SH3 protein 1
chr17_+_37026284 40.46 ENST00000433206.2
ENST00000435347.3
LIM and SH3 protein 1
chr6_-_86352642 39.13 ENST00000355238.6
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_4852332 38.55 ENST00000572383.1
profilin 1
chr1_+_29063271 38.41 ENST00000373812.3
YTH domain family, member 2
chr16_+_67596310 36.17 ENST00000264010.4
ENST00000401394.1
CCCTC-binding factor (zinc finger protein)
chr1_+_110881945 35.57 ENST00000602849.1
ENST00000487146.2
RNA binding motif protein 15
chr17_-_4852243 35.34 ENST00000225655.5
profilin 1
chr4_+_57301896 34.62 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr1_+_43148059 34.23 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr2_+_172778952 33.69 ENST00000392584.1
ENST00000264108.4
histone acetyltransferase 1
chr12_-_57081940 33.08 ENST00000436399.2
prostaglandin E synthase 3 (cytosolic)
chrX_-_16888448 32.73 ENST00000468092.1
ENST00000404022.1
ENST00000380087.2
retinoblastoma binding protein 7
chr4_-_174255536 32.24 ENST00000446922.2
high mobility group box 2
chr6_-_17706618 32.07 ENST00000262077.2
ENST00000537253.1
nucleoporin 153kDa
chr6_+_34204642 31.77 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr3_-_113465065 30.78 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr12_-_31479045 29.41 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr16_+_67063036 29.13 ENST00000290858.6
ENST00000564034.1
core-binding factor, beta subunit
chr1_+_27022485 28.94 ENST00000324856.7
AT rich interactive domain 1A (SWI-like)
chr13_-_31039375 28.38 ENST00000399494.1
high mobility group box 1
chr4_-_83351005 28.33 ENST00000295470.5
heterogeneous nuclear ribonucleoprotein D-like
chr16_+_67063142 28.28 ENST00000412916.2
core-binding factor, beta subunit
chr9_+_131451480 28.16 ENST00000322030.8
SET nuclear oncogene
chr11_-_46142948 27.96 ENST00000257821.4
PHD finger protein 21A
chr13_-_31040060 27.61 ENST00000326004.4
ENST00000341423.5
high mobility group box 1
chr16_-_50402690 27.13 ENST00000394689.2
bromodomain containing 7
chr16_-_50402836 26.52 ENST00000394688.3
bromodomain containing 7
chr11_-_46142615 26.18 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chrX_-_129244655 26.02 ENST00000335997.7
E74-like factor 4 (ets domain transcription factor)
chr17_-_61920280 25.75 ENST00000448276.2
ENST00000577990.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr1_-_183604794 25.37 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
actin related protein 2/3 complex, subunit 5, 16kDa
chr7_-_72936531 25.20 ENST00000339594.4
bromodomain adjacent to zinc finger domain, 1B
chr17_+_45728427 24.93 ENST00000540627.1
karyopherin (importin) beta 1
chr4_-_103748696 24.90 ENST00000321805.7
ubiquitin-conjugating enzyme E2D 3
chr1_-_32403903 24.85 ENST00000344035.6
ENST00000356536.3
protein tyrosine phosphatase type IVA, member 2
chr19_+_16222439 24.72 ENST00000300935.3
RAB8A, member RAS oncogene family
chr20_-_49547731 24.45 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr20_+_35234137 24.37 ENST00000344795.3
ENST00000373852.5
chromosome 20 open reading frame 24
chr9_-_35103105 24.34 ENST00000452248.2
ENST00000356493.5
stomatin (EPB72)-like 2
chr17_-_38574169 23.84 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr2_-_61765315 23.49 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chr6_+_47445467 23.47 ENST00000359314.5
CD2-associated protein
chr6_-_52149475 23.22 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
minichromosome maintenance complex component 3
chr16_-_87903079 23.16 ENST00000261622.4
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr20_+_35234223 22.95 ENST00000342422.3
chromosome 20 open reading frame 24
chr19_+_39138320 22.74 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
actinin, alpha 4
chr9_+_36572851 22.65 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chr18_-_48723690 22.59 ENST00000406189.3
mex-3 RNA binding family member C
chr14_-_75643296 22.29 ENST00000303575.4
transmembrane emp24-like trafficking protein 10 (yeast)
chrX_+_123094369 22.22 ENST00000455404.1
ENST00000218089.9
stromal antigen 2
chr15_+_57210961 22.12 ENST00000557843.1
transcription factor 12
chr16_+_85645007 22.07 ENST00000405402.2
Gse1 coiled-coil protein
chr2_+_219081817 21.88 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
actin related protein 2/3 complex, subunit 2, 34kDa
chr1_+_94883931 21.87 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ATP-binding cassette, sub-family D (ALD), member 3
chr19_+_16186903 21.82 ENST00000588507.1
tropomyosin 4
chr2_-_174828892 21.71 ENST00000418194.2
Sp3 transcription factor
chr11_-_67169265 21.57 ENST00000358239.4
ENST00000376745.4
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_+_47799446 21.50 ENST00000371873.5
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr4_-_103748271 21.40 ENST00000343106.5
ubiquitin-conjugating enzyme E2D 3
chr1_-_32403370 21.40 ENST00000534796.1
protein tyrosine phosphatase type IVA, member 2
chrX_-_129244454 21.29 ENST00000308167.5
E74-like factor 4 (ets domain transcription factor)
chr3_+_184079492 21.14 ENST00000456318.1
ENST00000412877.1
ENST00000438240.1
polymerase (RNA) II (DNA directed) polypeptide H
chr2_-_136633940 21.02 ENST00000264156.2
minichromosome maintenance complex component 6
chr8_-_67525473 20.94 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr4_-_83351294 20.55 ENST00000502762.1
heterogeneous nuclear ribonucleoprotein D-like
chr20_+_35202909 20.49 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr6_+_135502466 20.48 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr3_-_127872625 20.25 ENST00000464873.1
RuvB-like AAA ATPase 1
chr1_-_150208498 20.10 ENST00000314136.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr20_+_3776371 20.08 ENST00000245960.5
cell division cycle 25B
chr12_+_69004619 20.06 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr22_-_36784035 20.02 ENST00000216181.5
myosin, heavy chain 9, non-muscle
chr11_-_76091986 19.85 ENST00000260045.3
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr6_+_135502408 19.52 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr20_+_3776936 19.50 ENST00000439880.2
cell division cycle 25B
chr14_+_23790690 19.40 ENST00000556821.1
poly(A) binding protein, nuclear 1
chr12_-_58146128 19.20 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr20_+_47662805 19.17 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr11_+_63706444 19.17 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr1_+_94883991 19.16 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr17_-_42276574 19.12 ENST00000589805.1
ataxin 7-like 3
chr12_-_57082060 19.09 ENST00000448157.2
ENST00000414274.3
ENST00000262033.6
ENST00000456859.2
prostaglandin E synthase 3 (cytosolic)
chr14_-_23451467 19.07 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chr1_+_33116743 19.05 ENST00000414241.3
ENST00000373493.5
retinoblastoma binding protein 4
chr19_-_50432782 19.03 ENST00000413454.1
ENST00000596437.1
ENST00000341114.3
ENST00000595948.1
nucleoporin 62kDa
interleukin 4 induced 1
chr17_-_74733404 18.83 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
serine/arginine-rich splicing factor 2
chr17_+_36861735 18.61 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr1_-_150208412 18.61 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr15_+_57210818 18.54 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
transcription factor 12
chr2_-_48132814 18.54 ENST00000316377.4
ENST00000378314.3
F-box protein 11
chr12_+_96252706 18.53 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chrX_-_20284958 18.35 ENST00000379565.3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_+_56046990 18.28 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
kinectin 1 (kinesin receptor)
chr5_+_133450365 18.26 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
transcription factor 7 (T-cell specific, HMG-box)
chr3_+_152017181 18.23 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
muscleblind-like splicing regulator 1
chr12_-_58146048 18.18 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr6_+_20403997 18.14 ENST00000535432.1
E2F transcription factor 3
chr3_+_152017360 18.14 ENST00000485910.1
ENST00000463374.1
muscleblind-like splicing regulator 1
chr17_+_38278826 17.98 ENST00000577454.1
ENST00000578648.1
ENST00000579565.1
male-specific lethal 1 homolog (Drosophila)
chr20_+_31407692 17.96 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chr7_+_98972298 17.93 ENST00000252725.5
actin related protein 2/3 complex, subunit 1B, 41kDa
chr5_+_61602055 17.68 ENST00000381103.2
kinesin heavy chain member 2A
chr7_+_150756657 17.56 ENST00000413384.2
solute carrier family 4 (anion exchanger), member 2
chr2_-_174830430 17.54 ENST00000310015.6
ENST00000455789.2
Sp3 transcription factor
chr1_+_62901968 17.46 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
ubiquitin specific peptidase 1
chr12_+_98909351 17.27 ENST00000343315.5
ENST00000266732.4
ENST00000393053.2
thymopoietin
chr10_-_120840309 17.22 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr15_-_85259294 17.20 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11 homolog A (S. cerevisiae)
chr14_+_50359773 17.16 ENST00000298316.5
ADP-ribosylation factor 6
chr6_-_18265050 17.15 ENST00000397239.3
DEK oncogene
chr4_+_57302297 17.03 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr1_-_67896009 17.02 ENST00000370990.5
SERPINE1 mRNA binding protein 1
chr3_+_9439400 17.01 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SET domain containing 5
chr6_-_41909466 17.00 ENST00000414200.2
cyclin D3
chr2_-_38978492 16.95 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
serine/arginine-rich splicing factor 7
chr1_-_155904187 16.91 ENST00000368321.3
ENST00000368320.3
KIAA0907
chr13_+_114238997 16.79 ENST00000538138.1
ENST00000375370.5
transcription factor Dp-1
chr6_-_41909561 16.76 ENST00000372991.4
cyclin D3
chr19_+_3572925 16.75 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
high mobility group 20B
chr2_+_232573222 16.64 ENST00000341369.7
ENST00000409683.1
prothymosin, alpha
chr11_-_67169253 16.64 ENST00000527663.1
ENST00000312989.7
protein phosphatase 1, catalytic subunit, alpha isozyme
chr18_+_3449821 16.64 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr7_-_132766818 16.51 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr9_-_15510989 16.51 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PC4 and SFRS1 interacting protein 1
chr19_-_55919087 16.48 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
ubiquitin-conjugating enzyme E2S
chr2_+_232573208 16.38 ENST00000409115.3
prothymosin, alpha
chr1_+_113161778 16.31 ENST00000263168.3
capping protein (actin filament) muscle Z-line, alpha 1
chr8_-_17104356 16.27 ENST00000361272.4
ENST00000523917.1
CCR4-NOT transcription complex, subunit 7
chr4_-_83295103 16.27 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr17_+_7210898 16.26 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr1_-_67896095 16.24 ENST00000370994.4
SERPINE1 mRNA binding protein 1
chr6_+_37137939 16.22 ENST00000373509.5
pim-1 oncogene
chr14_+_56046914 16.15 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
kinectin 1 (kinesin receptor)
chr3_-_185655795 15.98 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
transformer 2 beta homolog (Drosophila)
chr1_-_150208363 15.90 ENST00000436748.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_+_133861790 15.89 ENST00000395003.1
jade family PHD finger 2
chr5_+_65222299 15.75 ENST00000284037.5
erbb2 interacting protein
chr9_+_33025209 15.68 ENST00000330899.4
ENST00000544625.1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr15_-_85259330 15.60 ENST00000560266.1
SEC11 homolog A (S. cerevisiae)
chr7_-_132766800 15.59 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr1_-_35658736 15.52 ENST00000357214.5
splicing factor proline/glutamine-rich
chr22_+_41347363 15.51 ENST00000216225.8
ring-box 1, E3 ubiquitin protein ligase
chr2_-_27632390 15.43 ENST00000350803.4
ENST00000344034.4
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr18_-_51751132 15.23 ENST00000256429.3
methyl-CpG binding domain protein 2
chr14_+_64970662 15.09 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chr18_+_3449695 15.03 ENST00000343820.5
TGFB-induced factor homeobox 1
chr1_-_67896069 15.02 ENST00000370995.2
ENST00000361219.6
SERPINE1 mRNA binding protein 1
chr18_+_29672573 14.99 ENST00000578107.1
ENST00000257190.5
ENST00000580499.1
ring finger protein 138, E3 ubiquitin protein ligase
chrX_+_123094672 14.92 ENST00000354548.5
ENST00000458700.1
stromal antigen 2
chr1_+_154947126 14.89 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chr15_-_85259384 14.78 ENST00000455959.3
SEC11 homolog A (S. cerevisiae)
chr20_-_49547910 14.77 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr16_-_28222797 14.68 ENST00000569951.1
ENST00000565698.1
exportin 6
chr7_+_116502605 14.61 ENST00000458284.2
ENST00000490693.1
capping protein (actin filament) muscle Z-line, alpha 2
chr2_+_86668464 14.57 ENST00000409064.1
lysine (K)-specific demethylase 3A
chr17_-_46178741 14.51 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr5_+_65440032 14.50 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr3_+_9439579 14.49 ENST00000406341.1
SET domain containing 5
chr2_-_153574480 14.35 ENST00000410080.1
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr1_-_156721502 14.31 ENST00000357325.5
hepatoma-derived growth factor
chr20_-_5100591 14.28 ENST00000379143.5
proliferating cell nuclear antigen
chr3_+_133292759 14.25 ENST00000431519.2
CDV3 homolog (mouse)
chr7_+_98972345 14.20 ENST00000418347.2
ENST00000429246.1
ENST00000417330.1
ENST00000431816.1
ENST00000427217.1
ENST00000458033.1
ENST00000451682.1
actin related protein 2/3 complex, subunit 1B, 41kDa
chr6_-_41909191 14.16 ENST00000512426.1
ENST00000372987.4
cyclin D3
chr2_-_48132924 14.13 ENST00000403359.3
F-box protein 11
chr15_+_75074410 14.08 ENST00000439220.2
c-src tyrosine kinase
chr17_-_46178527 14.01 ENST00000393408.3
chromobox homolog 1
chr11_+_85956182 14.01 ENST00000327320.4
ENST00000351625.6
ENST00000534595.1
embryonic ectoderm development
chr17_-_29151794 13.97 ENST00000324238.6
cytokine receptor-like factor 3
chr6_+_24775153 13.93 ENST00000356509.3
ENST00000230056.3
geminin, DNA replication inhibitor
chr4_-_100871506 13.92 ENST00000296417.5
H2A histone family, member Z
chr6_+_30689401 13.88 ENST00000396389.1
ENST00000396384.1
tubulin, beta class I
chr1_+_33116765 13.81 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
retinoblastoma binding protein 4
chrX_-_109561294 13.61 ENST00000372059.2
ENST00000262844.5
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_-_245027766 13.56 ENST00000283179.9
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr7_-_138794081 13.55 ENST00000464606.1
zinc finger CCCH-type, antiviral 1
chr20_+_306221 13.45 ENST00000342665.2
SRY (sex determining region Y)-box 12
chr14_+_24605361 13.35 ENST00000206451.6
ENST00000559123.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr5_+_6714718 13.33 ENST00000230859.6
ENST00000515721.1
PAP associated domain containing 7
chr9_+_110045537 13.29 ENST00000358015.3
RAD23 homolog B (S. cerevisiae)
chr2_+_136289030 13.21 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
R3H domain containing 1
chr17_-_62658186 13.19 ENST00000262435.9
SMAD specific E3 ubiquitin protein ligase 2
chr19_-_8070474 13.13 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1
chr15_-_69113218 13.13 ENST00000560303.1
ENST00000465139.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr10_+_70661014 13.03 ENST00000373585.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50

Network of associatons between targets according to the STRING database.

First level regulatory network of TFDP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
32.5 227.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
23.2 116.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
18.9 132.0 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
16.1 80.6 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
15.8 47.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
15.8 63.2 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
15.6 46.7 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
12.1 36.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
12.1 36.2 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
11.1 33.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
9.6 38.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
9.2 36.8 GO:0002572 pro-T cell differentiation(GO:0002572)
8.8 8.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
8.5 51.0 GO:0022614 membrane to membrane docking(GO:0022614)
8.4 84.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
8.4 67.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
7.9 31.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
7.8 23.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
7.6 30.2 GO:0031291 Ran protein signal transduction(GO:0031291)
7.4 73.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
7.4 22.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
6.7 20.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
6.7 20.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
6.7 46.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
6.5 39.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
6.3 31.4 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
6.2 30.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
6.1 24.3 GO:1901858 regulation of mitochondrial DNA replication(GO:0090296) regulation of mitochondrial DNA metabolic process(GO:1901858)
6.0 12.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
6.0 60.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
6.0 18.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
5.8 29.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
5.7 17.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
5.6 39.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
5.6 22.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
5.5 16.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
5.5 16.5 GO:0030474 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
5.4 16.3 GO:1901355 response to rapamycin(GO:1901355)
5.2 20.9 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
5.2 15.6 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
5.0 25.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
5.0 59.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
4.9 49.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
4.8 24.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
4.8 9.6 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
4.8 14.3 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
4.7 47.3 GO:0001866 NK T cell proliferation(GO:0001866)
4.5 31.5 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
4.3 56.1 GO:0006265 DNA topological change(GO:0006265)
4.3 12.8 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
4.2 58.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
4.2 4.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
4.1 41.4 GO:0007144 female meiosis I(GO:0007144)
4.1 20.7 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
4.1 16.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
4.1 12.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
4.0 12.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
4.0 12.0 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
4.0 11.9 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
4.0 11.9 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
3.9 11.8 GO:0001922 B-1 B cell homeostasis(GO:0001922)
3.9 19.5 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
3.8 26.8 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
3.8 11.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
3.8 11.5 GO:1903028 positive regulation of opsonization(GO:1903028)
3.8 15.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
3.7 15.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
3.7 11.2 GO:0010587 miRNA catabolic process(GO:0010587)
3.6 25.5 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
3.6 10.9 GO:0006172 ADP biosynthetic process(GO:0006172)
3.6 78.7 GO:0006337 nucleosome disassembly(GO:0006337)
3.5 21.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
3.5 31.5 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
3.5 164.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
3.4 13.7 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
3.4 23.9 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
3.4 23.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
3.3 16.7 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.3 16.6 GO:0015862 uridine transport(GO:0015862)
3.3 9.9 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
3.3 16.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
3.3 6.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
3.2 12.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
3.2 32.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
3.2 6.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
3.2 12.6 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
3.1 9.3 GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
3.1 15.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
3.1 21.7 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
3.1 15.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
3.1 18.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
3.1 12.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
3.0 48.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
3.0 9.0 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
3.0 18.0 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
3.0 3.0 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.0 14.8 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
2.9 5.9 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.9 20.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
2.9 38.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
2.9 23.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
2.9 8.6 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
2.9 94.1 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
2.8 31.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
2.8 64.8 GO:0043555 regulation of translation in response to stress(GO:0043555)
2.8 58.4 GO:0006465 signal peptide processing(GO:0006465)
2.8 2.8 GO:0032768 regulation of monooxygenase activity(GO:0032768)
2.7 8.2 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.7 8.2 GO:0052251 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
2.7 10.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
2.7 13.4 GO:0006167 AMP biosynthetic process(GO:0006167)
2.7 5.3 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
2.6 21.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.6 7.8 GO:0006597 spermine biosynthetic process(GO:0006597)
2.6 85.0 GO:0060216 definitive hemopoiesis(GO:0060216)
2.5 10.2 GO:0060623 regulation of chromosome condensation(GO:0060623)
2.5 15.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.5 15.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
2.5 32.7 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
2.5 20.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
2.5 12.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
2.4 29.3 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
2.4 14.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
2.4 9.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
2.4 7.2 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
2.4 26.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
2.4 7.1 GO:1902303 negative regulation of potassium ion export(GO:1902303)
2.3 7.0 GO:1903181 positive regulation of Wnt protein secretion(GO:0061357) regulation of late endosome to lysosome transport(GO:1902822) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of vacuolar transport(GO:1903336) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
2.3 25.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
2.3 20.5 GO:0006089 lactate metabolic process(GO:0006089)
2.3 6.8 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
2.2 13.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
2.2 8.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.2 13.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
2.2 10.9 GO:0021553 olfactory nerve development(GO:0021553)
2.2 6.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
2.2 8.6 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
2.2 17.2 GO:0051660 establishment of centrosome localization(GO:0051660)
2.1 12.9 GO:0007296 vitellogenesis(GO:0007296)
2.1 15.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
2.1 85.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
2.1 32.0 GO:0051639 actin filament network formation(GO:0051639)
2.1 10.5 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
2.1 176.9 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
2.1 20.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.1 24.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
2.1 14.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
2.0 6.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.0 14.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
2.0 35.9 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
2.0 43.5 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
2.0 5.9 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
2.0 7.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
2.0 3.9 GO:0060374 mast cell differentiation(GO:0060374)
2.0 7.9 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.0 21.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
1.9 7.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
1.9 19.1 GO:0006188 IMP biosynthetic process(GO:0006188)
1.9 9.5 GO:0060022 hard palate development(GO:0060022)
1.9 7.6 GO:0006543 glutamine catabolic process(GO:0006543)
1.9 5.7 GO:0032679 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.9 5.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
1.8 5.5 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.8 3.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
1.8 10.8 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
1.8 9.0 GO:0006740 NADPH regeneration(GO:0006740)
1.8 23.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
1.8 5.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.7 24.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.7 1.7 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
1.7 5.1 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
1.7 6.9 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
1.7 5.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.7 5.1 GO:0036071 N-glycan fucosylation(GO:0036071)
1.7 8.4 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
1.7 23.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.7 5.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.6 66.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.6 16.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.6 1.6 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
1.6 7.9 GO:0098502 DNA dephosphorylation(GO:0098502)
1.6 11.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
1.6 7.8 GO:0070734 histone H3-K27 methylation(GO:0070734)
1.6 9.3 GO:0072711 cellular response to hydroxyurea(GO:0072711)
1.5 9.0 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
1.5 8.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
1.5 50.0 GO:0006270 DNA replication initiation(GO:0006270)
1.5 10.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.5 32.1 GO:0008053 mitochondrial fusion(GO:0008053)
1.5 5.8 GO:0045218 zonula adherens maintenance(GO:0045218)
1.5 7.3 GO:0030047 actin modification(GO:0030047)
1.4 5.8 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.4 59.0 GO:0043486 histone exchange(GO:0043486)
1.4 10.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
1.4 15.7 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
1.4 36.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.4 14.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
1.4 7.0 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
1.4 8.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
1.4 5.5 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
1.4 24.7 GO:1903540 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
1.4 12.3 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
1.4 4.1 GO:1902309 regulation of peptidyl-serine dephosphorylation(GO:1902308) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.4 2.7 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.3 18.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.3 22.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
1.3 23.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
1.3 2.6 GO:0061511 centriole elongation(GO:0061511)
1.3 10.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.3 16.6 GO:0038092 nodal signaling pathway(GO:0038092)
1.3 6.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
1.3 10.1 GO:0000212 meiotic spindle organization(GO:0000212)
1.3 3.8 GO:0008063 Toll signaling pathway(GO:0008063)
1.3 11.3 GO:0051382 kinetochore assembly(GO:0051382)
1.3 17.5 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
1.2 6.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
1.2 14.5 GO:0010225 response to UV-C(GO:0010225)
1.2 6.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.2 22.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
1.2 25.2 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.2 14.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
1.2 3.6 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.2 7.2 GO:0043418 homocysteine catabolic process(GO:0043418)
1.2 2.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
1.2 16.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
1.1 22.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.1 8.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
1.1 9.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.1 11.0 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
1.1 4.4 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
1.1 5.4 GO:2000035 regulation of stem cell division(GO:2000035)
1.1 21.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
1.1 11.8 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
1.1 2.1 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
1.1 4.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
1.1 6.3 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
1.1 19.0 GO:0051014 actin filament severing(GO:0051014)
1.1 4.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.0 15.6 GO:0033197 response to vitamin E(GO:0033197)
1.0 4.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
1.0 5.1 GO:0006449 regulation of translational termination(GO:0006449)
1.0 5.0 GO:0050957 equilibrioception(GO:0050957)
1.0 3.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
1.0 3.0 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
1.0 6.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.0 6.0 GO:2000510 peptide antigen assembly with MHC protein complex(GO:0002501) positive regulation of dendritic cell chemotaxis(GO:2000510)
1.0 7.0 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
1.0 6.9 GO:0006116 NADH oxidation(GO:0006116)
1.0 11.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
1.0 63.2 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
1.0 1.0 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.0 9.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.9 2.8 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.9 2.8 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.9 10.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.9 2.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.9 2.8 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.9 15.8 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.9 6.3 GO:0030220 platelet formation(GO:0030220)
0.9 2.6 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.9 6.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.9 2.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.9 4.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.9 3.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.9 3.4 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.8 19.5 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.8 1.7 GO:1902903 regulation of fibril organization(GO:1902903)
0.8 4.2 GO:0046836 glycolipid transport(GO:0046836)
0.8 4.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.8 8.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.8 22.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.8 4.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.8 11.2 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.8 8.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.8 28.1 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.8 10.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.8 2.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.7 0.7 GO:1990791 dorsal root ganglion development(GO:1990791)
0.7 8.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.7 14.6 GO:0006342 chromatin silencing(GO:0006342)
0.7 10.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.7 10.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.7 2.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.7 2.2 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.7 4.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.7 2.8 GO:0030242 pexophagy(GO:0030242)
0.7 5.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.7 2.8 GO:0090670 RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672) regulation of telomerase RNA localization to Cajal body(GO:1904872)
0.7 19.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.7 8.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.7 7.5 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.7 0.7 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.7 4.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.7 3.3 GO:0071462 cellular response to water deprivation(GO:0042631) cellular response to water stimulus(GO:0071462)
0.7 10.6 GO:0051683 establishment of Golgi localization(GO:0051683)
0.7 2.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.7 6.6 GO:0035855 megakaryocyte development(GO:0035855)
0.6 4.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.6 1.9 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.6 1.9 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.6 2.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.6 5.1 GO:0010265 SCF complex assembly(GO:0010265)
0.6 7.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 3.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.6 2.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.6 2.5 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.6 4.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.6 3.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.6 2.4 GO:0042418 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.6 6.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.6 3.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.6 3.6 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.6 1.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.6 3.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.6 10.0 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.6 0.6 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.6 2.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.6 3.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.6 9.8 GO:0007035 vacuolar acidification(GO:0007035)
0.6 12.7 GO:0002063 chondrocyte development(GO:0002063)
0.6 34.3 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.6 2.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.6 10.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.6 21.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.6 5.6 GO:0006612 protein targeting to membrane(GO:0006612)
0.6 3.4 GO:0051013 microtubule severing(GO:0051013)
0.6 3.9 GO:0019054 modulation by virus of host process(GO:0019054)
0.6 1.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.6 10.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.5 2.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.5 3.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.5 6.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.5 2.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.5 9.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.5 19.5 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.5 8.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.5 2.6 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.5 2.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.5 1.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.5 6.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.5 3.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.5 10.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.5 1.5 GO:0080009 mRNA methylation(GO:0080009)
0.5 13.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.5 45.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.5 2.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.5 0.9 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 39.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.5 34.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 5.1 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.5 4.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.5 5.1 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.5 6.9 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.5 5.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.5 5.9 GO:0042026 protein refolding(GO:0042026)
0.4 4.0 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.4 1.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.4 4.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4 7.1 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 3.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.4 7.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.4 3.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 3.0 GO:0023035 CD40 signaling pathway(GO:0023035)
0.4 17.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.4 5.1 GO:0019985 translesion synthesis(GO:0019985)
0.4 5.1 GO:0090527 actin filament reorganization(GO:0090527)
0.4 6.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.4 29.0 GO:0051225 spindle assembly(GO:0051225)
0.4 1.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 1.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.4 15.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.4 2.0 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.4 2.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 2.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.4 12.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.4 1.5 GO:0030252 growth hormone secretion(GO:0030252)
0.4 1.5 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.4 0.4 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.4 4.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4 16.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.4 2.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.4 9.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.4 3.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.4 9.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.4 2.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 1.8 GO:0042659 regulation of cell fate specification(GO:0042659)
0.4 1.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3 2.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 3.5 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 0.3 GO:0072553 terminal button organization(GO:0072553)
0.3 1.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.3 1.4 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.3 5.7 GO:0034629 cellular protein complex localization(GO:0034629)
0.3 1.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 11.7 GO:0006414 translational elongation(GO:0006414)
0.3 1.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 1.0 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.3 17.5 GO:0016575 histone deacetylation(GO:0016575)
0.3 0.9 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.3 1.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.3 0.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 24.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 2.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.3 3.0 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.3 2.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.3 2.7 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.3 3.2 GO:0031648 protein destabilization(GO:0031648)
0.3 2.3 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.3 2.0 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.3 2.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 2.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 2.3 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 9.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.3 2.5 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.3 7.2 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.3 7.2 GO:0006412 translation(GO:0006412)
0.3 6.3 GO:0032392 DNA geometric change(GO:0032392)
0.3 6.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.3 14.1 GO:0015701 bicarbonate transport(GO:0015701)
0.3 1.6 GO:0070375 ERK5 cascade(GO:0070375)
0.3 0.5 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.3 3.5 GO:0009303 rRNA transcription(GO:0009303)
0.2 0.5 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.2 GO:0016458 gene silencing(GO:0016458)
0.2 4.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.9 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.2 3.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 2.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 24.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 8.2 GO:0007031 peroxisome organization(GO:0007031)
0.2 1.6 GO:0032479 regulation of type I interferon production(GO:0032479)
0.2 6.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 1.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 2.4 GO:0032310 prostaglandin secretion(GO:0032310)
0.2 1.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.3 GO:0001782 B cell homeostasis(GO:0001782)
0.2 7.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 21.4 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.2 12.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 6.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 20.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 7.6 GO:0006611 protein export from nucleus(GO:0006611)
0.2 5.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.2 2.0 GO:0045116 protein neddylation(GO:0045116)
0.2 4.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.2 1.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 5.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 0.8 GO:0043970 histone H3-K9 acetylation(GO:0043970) regulation of histone H3-K9 acetylation(GO:2000615)
0.2 9.2 GO:0031100 organ regeneration(GO:0031100)
0.2 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.5 GO:0031297 replication fork processing(GO:0031297)
0.2 4.9 GO:0007140 male meiosis(GO:0007140)
0.2 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.2 10.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 8.7 GO:0016266 O-glycan processing(GO:0016266)
0.2 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.7 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.2 1.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 1.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 2.5 GO:0072348 sulfur compound transport(GO:0072348)
0.2 4.3 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.2 1.3 GO:0002192 IRES-dependent translational initiation(GO:0002192)
0.2 6.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 0.5 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2 1.5 GO:0035065 regulation of histone acetylation(GO:0035065)
0.2 0.6 GO:0071801 regulation of podosome assembly(GO:0071801)
0.1 0.7 GO:0097338 response to clozapine(GO:0097338)
0.1 1.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 1.4 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.7 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 1.0 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 5.4 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 15.3 GO:0070268 cornification(GO:0070268)
0.1 3.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 4.9 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 1.0 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 5.4 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.1 1.0 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.1 0.4 GO:0009447 putrescine catabolic process(GO:0009447)
0.1 2.3 GO:0030033 microvillus assembly(GO:0030033)
0.1 2.5 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.2 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.4 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 1.8 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 4.3 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.1 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 4.7 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 1.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 5.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 4.4 GO:0006968 cellular defense response(GO:0006968)
0.1 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 2.5 GO:0019835 cytolysis(GO:0019835)
0.1 0.2 GO:0060459 subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.9 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 4.8 GO:0008033 tRNA processing(GO:0008033)
0.1 0.3 GO:0071389 cellular response to corticosterone stimulus(GO:0071386) cellular response to mineralocorticoid stimulus(GO:0071389)
0.1 2.2 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 2.4 GO:0045445 myoblast differentiation(GO:0045445)
0.1 0.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 1.3 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0060346 bone trabecula formation(GO:0060346)
0.0 2.4 GO:1903391 regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of adherens junction organization(GO:1903391)
0.0 0.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.1 GO:0030810 positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.0 1.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0033260 nuclear DNA replication(GO:0033260)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
24.3 194.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
8.4 33.7 GO:0033186 CAF-1 complex(GO:0033186)
8.3 58.4 GO:0005787 signal peptidase complex(GO:0005787)
7.9 23.8 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
7.8 77.7 GO:0001739 sex chromatin(GO:0001739)
7.7 23.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
7.3 21.9 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
7.1 28.6 GO:0001740 Barr body(GO:0001740)
6.7 20.0 GO:0005826 actomyosin contractile ring(GO:0005826)
6.4 154.5 GO:0071564 npBAF complex(GO:0071564)
6.4 76.8 GO:0090544 BAF-type complex(GO:0090544)
6.2 24.9 GO:0032301 MutSalpha complex(GO:0032301)
6.2 6.2 GO:0032839 dendrite cytoplasm(GO:0032839)
5.9 41.2 GO:0031415 NatA complex(GO:0031415)
5.8 40.9 GO:0005663 DNA replication factor C complex(GO:0005663)
5.7 22.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
5.5 33.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
5.5 16.5 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
5.4 59.1 GO:0005642 annulate lamellae(GO:0005642)
5.3 26.3 GO:0097422 tubular endosome(GO:0097422)
5.2 93.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
5.2 15.5 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
5.1 76.9 GO:0042405 nuclear inclusion body(GO:0042405)
5.1 51.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
5.1 20.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
5.0 25.0 GO:0001940 male pronucleus(GO:0001940)
5.0 19.8 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
4.8 62.1 GO:0042555 MCM complex(GO:0042555)
4.7 99.0 GO:0000812 Swr1 complex(GO:0000812)
4.6 46.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
4.6 32.1 GO:0061617 MICOS complex(GO:0061617)
4.3 25.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
4.0 19.8 GO:0035061 interchromatin granule(GO:0035061)
3.9 23.2 GO:0008537 proteasome activator complex(GO:0008537)
3.6 61.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
3.6 10.7 GO:0030689 Noc complex(GO:0030689)
3.4 13.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
3.4 23.5 GO:0090543 Flemming body(GO:0090543)
3.2 9.6 GO:0005726 perichromatin fibrils(GO:0005726)
3.1 25.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
3.1 87.5 GO:0031143 pseudopodium(GO:0031143)
3.1 9.3 GO:0031523 Myb complex(GO:0031523)
3.1 9.3 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
3.0 18.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
2.7 13.7 GO:0097149 centralspindlin complex(GO:0097149)
2.7 19.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
2.7 8.0 GO:0043291 RAVE complex(GO:0043291)
2.6 39.6 GO:0008290 F-actin capping protein complex(GO:0008290)
2.6 7.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
2.6 38.9 GO:0005641 nuclear envelope lumen(GO:0005641)
2.6 12.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
2.5 7.4 GO:0071159 NF-kappaB complex(GO:0071159)
2.5 4.9 GO:0035189 Rb-E2F complex(GO:0035189)
2.4 45.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
2.4 23.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.4 7.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
2.4 80.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
2.3 7.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
2.2 11.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
2.2 24.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.1 289.0 GO:0016605 PML body(GO:0016605)
2.1 8.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
2.1 21.2 GO:0000796 condensin complex(GO:0000796)
2.1 14.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
2.1 14.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
2.0 21.9 GO:0005688 U6 snRNP(GO:0005688)
1.9 17.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.9 15.5 GO:0042382 paraspeckles(GO:0042382)
1.9 17.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.9 32.4 GO:0032059 bleb(GO:0032059)
1.9 41.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.8 9.2 GO:0044530 supraspliceosomal complex(GO:0044530)
1.8 18.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.8 8.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.8 14.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.8 31.5 GO:0005721 pericentric heterochromatin(GO:0005721)
1.7 6.9 GO:0071001 U4/U6 snRNP(GO:0071001)
1.7 34.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.7 11.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.7 5.1 GO:0033565 ESCRT-0 complex(GO:0033565)
1.7 47.0 GO:0005719 nuclear euchromatin(GO:0005719)
1.6 75.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.6 25.6 GO:0035861 site of double-strand break(GO:0035861)
1.5 15.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.5 40.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
1.5 9.2 GO:0032039 integrator complex(GO:0032039)
1.5 24.4 GO:0036020 endolysosome membrane(GO:0036020)
1.5 7.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
1.5 10.5 GO:0046581 intercellular canaliculus(GO:0046581)
1.5 13.5 GO:0044666 MLL3/4 complex(GO:0044666)
1.5 6.0 GO:0000811 GINS complex(GO:0000811)
1.4 18.7 GO:0097227 sperm annulus(GO:0097227)
1.4 156.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
1.4 8.6 GO:0032444 activin responsive factor complex(GO:0032444)
1.4 7.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.4 7.0 GO:0016589 NURF complex(GO:0016589)
1.4 9.8 GO:0034709 methylosome(GO:0034709)
1.4 76.7 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
1.4 9.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.4 6.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.3 18.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.3 32.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
1.3 17.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.3 19.0 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.3 13.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.3 6.3 GO:0032021 NELF complex(GO:0032021)
1.2 6.0 GO:0030014 CCR4-NOT complex(GO:0030014)
1.2 6.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.2 35.4 GO:0005680 anaphase-promoting complex(GO:0005680)
1.1 14.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.1 3.4 GO:0031298 replication fork protection complex(GO:0031298)
1.1 14.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.1 5.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
1.1 75.2 GO:0005637 nuclear inner membrane(GO:0005637)
1.1 5.5 GO:0042643 actomyosin, actin portion(GO:0042643)
1.1 7.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.1 12.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.1 4.2 GO:0042575 DNA polymerase complex(GO:0042575)
1.0 44.7 GO:1990391 DNA repair complex(GO:1990391)
1.0 5.1 GO:0032449 CBM complex(GO:0032449)
1.0 10.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.0 7.0 GO:0072487 MSL complex(GO:0072487)
1.0 3.0 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
1.0 4.8 GO:0001652 granular component(GO:0001652)
0.9 5.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.9 5.6 GO:0010369 chromocenter(GO:0010369)
0.9 28.9 GO:0042101 T cell receptor complex(GO:0042101)
0.9 2.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.9 5.5 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.9 1.8 GO:0005667 transcription factor complex(GO:0005667)
0.9 4.3 GO:0034457 Mpp10 complex(GO:0034457)
0.8 46.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.8 56.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.8 3.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.8 6.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.8 3.9 GO:0071817 MMXD complex(GO:0071817)
0.8 77.2 GO:0016363 nuclear matrix(GO:0016363)
0.7 6.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.7 57.8 GO:0005811 lipid particle(GO:0005811)
0.7 103.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.7 15.0 GO:0070822 Sin3-type complex(GO:0070822)
0.7 7.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.7 17.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.7 2.7 GO:0043596 nuclear replication fork(GO:0043596)
0.6 5.8 GO:0005915 zonula adherens(GO:0005915)
0.6 2.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.6 17.3 GO:0097228 sperm principal piece(GO:0097228)
0.6 5.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.6 2.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.6 5.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.6 6.2 GO:0097413 Lewy body(GO:0097413)
0.6 3.4 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.5 51.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.5 7.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.5 3.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.5 4.6 GO:0005827 polar microtubule(GO:0005827)
0.5 4.6 GO:0000815 ESCRT III complex(GO:0000815)
0.5 1.5 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.5 3.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.5 3.0 GO:0001520 outer dense fiber(GO:0001520)
0.5 9.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 13.4 GO:0000421 autophagosome membrane(GO:0000421)
0.5 6.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.5 5.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.5 154.2 GO:0000785 chromatin(GO:0000785)
0.5 11.0 GO:0031941 filamentous actin(GO:0031941)
0.5 3.2 GO:0005916 fascia adherens(GO:0005916)
0.4 3.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.4 93.8 GO:0072562 blood microparticle(GO:0072562)
0.4 1.7 GO:0005846 nuclear cap binding complex(GO:0005846)
0.4 21.2 GO:0005681 spliceosomal complex(GO:0005681)
0.4 3.8 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.4 11.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 20.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.4 2.0 GO:0044326 dendritic spine neck(GO:0044326)
0.4 1.6 GO:1990423 RZZ complex(GO:1990423)
0.4 93.5 GO:0031965 nuclear membrane(GO:0031965)
0.4 2.8 GO:0005871 kinesin complex(GO:0005871)
0.4 2.5 GO:0070187 telosome(GO:0070187)
0.3 19.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 2.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 4.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 1.4 GO:0030314 junctional membrane complex(GO:0030314)
0.3 11.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 1.2 GO:0005875 microtubule associated complex(GO:0005875)
0.3 3.9 GO:0005869 dynactin complex(GO:0005869)
0.3 0.6 GO:0042587 glycogen granule(GO:0042587)
0.3 3.0 GO:0005814 centriole(GO:0005814)
0.3 11.3 GO:0002102 podosome(GO:0002102)
0.3 1.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.3 4.9 GO:0032433 filopodium tip(GO:0032433)
0.3 6.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 2.0 GO:0005938 cell cortex(GO:0005938)
0.3 3.9 GO:0000242 pericentriolar material(GO:0000242)
0.3 7.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 4.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 9.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 21.9 GO:0000922 spindle pole(GO:0000922)
0.2 29.7 GO:0030496 midbody(GO:0030496)
0.2 30.8 GO:0005635 nuclear envelope(GO:0005635)
0.2 8.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.2 1.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 19.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 25.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 0.8 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.2 0.6 GO:0032280 symmetric synapse(GO:0032280)
0.2 6.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 4.2 GO:0072686 mitotic spindle(GO:0072686)
0.2 1.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 9.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 2.6 GO:0030686 90S preribosome(GO:0030686)
0.1 11.6 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 11.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 3.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 5.4 GO:0045095 keratin filament(GO:0045095)
0.1 10.2 GO:0005819 spindle(GO:0005819)
0.1 3.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 3.9 GO:0042629 mast cell granule(GO:0042629)
0.1 7.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 3.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 9.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 1.1 GO:0045177 apical part of cell(GO:0045177)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.4 GO:0005844 polysome(GO:0005844)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 9.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.5 GO:0031932 TORC2 complex(GO:0031932)
0.1 3.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 4.3 GO:0035579 specific granule membrane(GO:0035579)
0.1 0.5 GO:0061574 ASAP complex(GO:0061574)
0.1 0.3 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 10.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.6 GO:0005795 Golgi stack(GO:0005795)
0.0 7.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 5.9 GO:0005925 focal adhesion(GO:0005925)
0.0 1.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
13.0 52.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
12.1 36.4 GO:0001069 regulatory region RNA binding(GO:0001069)
11.6 46.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
11.2 145.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
10.5 63.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
9.8 117.7 GO:0031386 protein tag(GO:0031386)
9.6 86.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
8.1 32.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
7.9 23.8 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
6.7 80.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
6.2 24.9 GO:0032143 single thymine insertion binding(GO:0032143)
5.7 22.8 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
5.5 60.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
5.1 5.1 GO:0032427 GBD domain binding(GO:0032427)
4.9 14.8 GO:0031859 platelet activating factor receptor binding(GO:0031859)
4.8 14.3 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
4.6 60.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
4.6 139.1 GO:0008143 poly(A) binding(GO:0008143)
4.5 31.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
4.4 26.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
4.3 12.9 GO:0034452 dynactin binding(GO:0034452)
4.2 129.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
4.1 16.4 GO:0034057 RNA strand-exchange activity(GO:0034057)
4.0 12.1 GO:0033149 FFAT motif binding(GO:0033149)
4.0 12.0 GO:0004802 transketolase activity(GO:0004802)
4.0 12.0 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
3.8 26.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
3.8 19.1 GO:0008420 CTD phosphatase activity(GO:0008420)
3.7 55.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
3.7 14.6 GO:0004743 pyruvate kinase activity(GO:0004743)
3.7 21.9 GO:0042610 CD8 receptor binding(GO:0042610)
3.6 127.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
3.6 10.9 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
3.6 25.3 GO:0070717 poly-purine tract binding(GO:0070717)
3.6 21.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
3.5 21.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
3.5 24.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.5 24.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
3.4 37.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
3.4 13.5 GO:0043398 HLH domain binding(GO:0043398)
3.4 23.5 GO:0050733 RS domain binding(GO:0050733)
3.3 40.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
3.3 10.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
3.3 23.2 GO:0061133 endopeptidase activator activity(GO:0061133)
3.3 16.5 GO:0097100 supercoiled DNA binding(GO:0097100)
3.3 9.9 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
3.3 29.6 GO:1990226 histone methyltransferase binding(GO:1990226)
3.3 42.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
3.2 139.7 GO:0004407 histone deacetylase activity(GO:0004407)
3.2 129.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
3.1 9.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
3.0 11.9 GO:0016748 succinyltransferase activity(GO:0016748)
2.8 73.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.8 11.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
2.7 8.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
2.7 24.5 GO:1901612 cardiolipin binding(GO:1901612)
2.6 15.7 GO:0030957 Tat protein binding(GO:0030957)
2.6 114.7 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
2.6 7.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
2.5 15.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.5 17.5 GO:0000400 four-way junction DNA binding(GO:0000400)
2.5 27.3 GO:0001222 transcription corepressor binding(GO:0001222)
2.5 17.2 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
2.4 14.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
2.4 43.6 GO:0017070 U6 snRNA binding(GO:0017070)
2.4 42.7 GO:0035497 cAMP response element binding(GO:0035497)
2.4 37.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
2.3 9.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
2.3 16.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
2.3 6.9 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.3 9.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
2.3 13.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
2.2 6.7 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
2.2 11.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.2 6.7 GO:1901611 phosphatidylglycerol binding(GO:1901611)
2.2 15.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.2 34.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
2.2 10.8 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.1 19.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
2.1 6.3 GO:0004137 deoxycytidine kinase activity(GO:0004137)
2.1 43.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
2.1 8.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
2.1 43.2 GO:0016881 acid-amino acid ligase activity(GO:0016881)
2.0 10.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
2.0 7.9 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.0 21.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
2.0 5.9 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
2.0 11.8 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
1.9 5.6 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.8 23.2 GO:0038132 neuregulin binding(GO:0038132)
1.8 3.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.8 5.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.7 7.0 GO:0008384 IkappaB kinase activity(GO:0008384)
1.7 5.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
1.7 5.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.6 6.6 GO:1990446 U1 snRNP binding(GO:1990446)
1.6 4.9 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
1.6 87.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
1.6 21.0 GO:0045294 alpha-catenin binding(GO:0045294)
1.6 7.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.6 24.9 GO:0042609 CD4 receptor binding(GO:0042609)
1.6 10.9 GO:0004017 adenylate kinase activity(GO:0004017)
1.6 12.4 GO:0019237 centromeric DNA binding(GO:0019237)
1.5 4.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.5 7.6 GO:0004359 glutaminase activity(GO:0004359)
1.5 183.3 GO:0003697 single-stranded DNA binding(GO:0003697)
1.5 7.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.5 32.9 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.5 4.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.5 5.9 GO:0038025 reelin receptor activity(GO:0038025)
1.5 4.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
1.5 46.5 GO:0051059 NF-kappaB binding(GO:0051059)
1.4 41.6 GO:0070410 co-SMAD binding(GO:0070410)
1.4 39.0 GO:0042288 MHC class I protein binding(GO:0042288)
1.4 12.5 GO:0030620 U2 snRNA binding(GO:0030620)
1.4 9.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.4 16.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.4 9.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
1.3 75.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.3 22.2 GO:0005522 profilin binding(GO:0005522)
1.3 15.6 GO:0000339 RNA cap binding(GO:0000339)
1.3 5.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
1.3 7.6 GO:0035613 RNA stem-loop binding(GO:0035613)
1.3 10.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.2 46.1 GO:0036002 pre-mRNA binding(GO:0036002)
1.2 7.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.2 8.7 GO:0046790 virion binding(GO:0046790)
1.2 16.1 GO:0031996 thioesterase binding(GO:0031996)
1.2 8.6 GO:0070569 uridylyltransferase activity(GO:0070569)
1.2 15.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.2 83.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
1.2 6.0 GO:0001849 complement component C1q binding(GO:0001849)
1.2 58.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
1.2 10.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
1.2 7.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.2 45.0 GO:0008536 Ran GTPase binding(GO:0008536)
1.1 3.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.1 17.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
1.1 3.4 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.1 13.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.1 6.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.1 22.8 GO:0005521 lamin binding(GO:0005521)
1.1 18.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.1 7.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.1 8.6 GO:0004064 arylesterase activity(GO:0004064)
1.1 7.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.1 4.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.1 4.2 GO:0017089 glycolipid transporter activity(GO:0017089)
1.1 17.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
1.0 6.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
1.0 17.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.0 3.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.0 33.7 GO:0042605 peptide antigen binding(GO:0042605)
1.0 3.0 GO:0036033 mediator complex binding(GO:0036033)
1.0 17.1 GO:0043495 protein anchor(GO:0043495)
1.0 14.9 GO:0070403 NAD+ binding(GO:0070403)
1.0 4.9 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
1.0 1.0 GO:0070878 primary miRNA binding(GO:0070878)
1.0 1.0 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.0 14.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.0 1.9 GO:0097001 ceramide binding(GO:0097001)
1.0 3.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.9 2.8 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.9 2.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.9 2.8 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.9 3.6 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.9 11.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.9 33.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.9 18.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.9 4.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.9 8.8 GO:0042301 phosphate ion binding(GO:0042301)
0.9 2.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.9 3.5 GO:0016531 copper chaperone activity(GO:0016531)
0.9 25.3 GO:0070064 proline-rich region binding(GO:0070064)
0.9 4.3 GO:1990254 keratin filament binding(GO:1990254)
0.9 8.6 GO:0030274 LIM domain binding(GO:0030274)
0.9 2.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.9 3.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.9 2.6 GO:0048030 disaccharide binding(GO:0048030)
0.8 5.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.8 18.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 5.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.8 2.4 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.8 6.4 GO:0051525 NFAT protein binding(GO:0051525)
0.8 45.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.8 11.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.8 16.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.8 55.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.8 17.8 GO:0031489 myosin V binding(GO:0031489)
0.8 13.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.7 93.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.7 13.2 GO:0097602 cullin family protein binding(GO:0097602)
0.7 2.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.7 14.4 GO:0051400 BH domain binding(GO:0051400)
0.7 2.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.7 2.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.7 7.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.7 18.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.7 147.0 GO:0051015 actin filament binding(GO:0051015)
0.7 4.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 17.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.7 10.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.7 6.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.7 7.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.7 11.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.6 9.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 6.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 2.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.6 15.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.6 11.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.6 7.7 GO:0015926 glucosidase activity(GO:0015926)
0.6 43.0 GO:0032947 protein complex scaffold(GO:0032947)
0.6 10.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.5 9.3 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.5 11.9 GO:0004697 protein kinase C activity(GO:0004697)
0.5 5.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 2.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.5 2.6 GO:1990460 leptin receptor binding(GO:1990460)
0.5 35.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.5 5.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 3.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.5 8.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.5 12.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 9.8 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.5 2.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 1.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.5 13.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.4 1.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.4 3.1 GO:0048156 tau protein binding(GO:0048156)
0.4 6.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 9.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.4 7.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 1.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.4 13.3 GO:0003678 DNA helicase activity(GO:0003678)
0.4 7.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 12.7 GO:0019956 chemokine binding(GO:0019956)
0.4 2.1 GO:0003680 AT DNA binding(GO:0003680)
0.4 3.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 4.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 25.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.4 17.4 GO:0050681 androgen receptor binding(GO:0050681)
0.4 5.5 GO:0031491 nucleosome binding(GO:0031491)
0.4 7.8 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.4 6.6 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.4 1.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 17.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.4 32.6 GO:0042393 histone binding(GO:0042393)
0.4 6.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 1.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 7.3 GO:0030275 LRR domain binding(GO:0030275)
0.3 3.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.3 4.8 GO:0000287 magnesium ion binding(GO:0000287)
0.3 7.7 GO:0030515 snoRNA binding(GO:0030515)
0.3 4.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 5.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.3 1.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 13.4 GO:0002039 p53 binding(GO:0002039)
0.3 1.3 GO:0045182 translation regulator activity(GO:0045182)
0.3 2.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 1.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 2.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 23.9 GO:0004386 helicase activity(GO:0004386)
0.3 10.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 2.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 2.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 0.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 2.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 14.0 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.3 7.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 5.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 2.9 GO:0019206 nucleoside kinase activity(GO:0019206)
0.3 50.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 74.2 GO:0045296 cadherin binding(GO:0045296)
0.2 14.1 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.0 GO:0032810 sterol response element binding(GO:0032810)
0.2 2.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 3.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 7.4 GO:0030145 manganese ion binding(GO:0030145)
0.2 1.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.2 9.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 16.4 GO:0008565 protein transporter activity(GO:0008565)
0.2 0.6 GO:0009881 photoreceptor activity(GO:0009881)
0.2 20.5 GO:0000149 SNARE binding(GO:0000149)
0.2 1.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 2.1 GO:0017091 AU-rich element binding(GO:0017091)
0.2 2.3 GO:0070628 proteasome binding(GO:0070628)
0.2 2.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 5.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.2 0.7 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.2 1.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 4.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 6.8 GO:0005198 structural molecule activity(GO:0005198)
0.1 0.5 GO:0003690 double-stranded DNA binding(GO:0003690)
0.1 2.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 5.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 19.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.1 GO:0008483 transaminase activity(GO:0008483)
0.1 5.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.0 GO:0046332 SMAD binding(GO:0046332)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 7.2 GO:0031072 heat shock protein binding(GO:0031072)
0.1 3.8 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 3.1 GO:0004527 exonuclease activity(GO:0004527)
0.1 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 4.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.8 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.6 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 56.9 GO:0003723 RNA binding(GO:0003723)
0.1 5.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.2 GO:0004672 protein kinase activity(GO:0004672)
0.1 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.0 12.0 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.0 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.0 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 138.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
2.6 76.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
2.4 82.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
2.1 30.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.1 52.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.9 188.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
1.9 46.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.8 38.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
1.8 222.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
1.7 94.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
1.7 87.0 PID FANCONI PATHWAY Fanconi anemia pathway
1.6 16.2 PID IL5 PATHWAY IL5-mediated signaling events
1.5 57.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.5 26.3 PID BARD1 PATHWAY BARD1 signaling events
1.4 51.4 PID ALK1 PATHWAY ALK1 signaling events
1.4 114.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
1.4 5.5 ST JAK STAT PATHWAY Jak-STAT Pathway
1.3 10.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
1.3 132.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.3 13.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.2 3.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
1.2 91.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
1.2 33.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
1.2 58.9 PID AURORA B PATHWAY Aurora B signaling
1.1 59.2 PID P53 REGULATION PATHWAY p53 pathway
1.1 50.9 PID ILK PATHWAY Integrin-linked kinase signaling
1.1 61.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.1 74.8 PID CDC42 PATHWAY CDC42 signaling events
1.0 23.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.0 15.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.0 32.0 PID RHOA PATHWAY RhoA signaling pathway
1.0 42.5 PID PLK1 PATHWAY PLK1 signaling events
1.0 52.4 PID E2F PATHWAY E2F transcription factor network
0.9 15.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.8 12.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.8 21.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.8 7.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.7 24.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.6 7.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.6 14.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.5 10.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.5 3.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.5 15.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 33.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.4 20.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 15.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.4 5.4 PID ATM PATHWAY ATM pathway
0.3 5.4 PID ATR PATHWAY ATR signaling pathway
0.3 6.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 20.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 10.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 4.9 PID ARF 3PATHWAY Arf1 pathway
0.2 5.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 4.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 2.5 PID EPO PATHWAY EPO signaling pathway
0.2 2.2 PID NOTCH PATHWAY Notch signaling pathway
0.2 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 10.8 PID CMYB PATHWAY C-MYB transcription factor network
0.2 4.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 9.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.5 PID FOXO PATHWAY FoxO family signaling
0.1 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 5.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 127.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
6.3 56.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
4.6 59.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
4.3 68.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
4.0 68.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
3.7 162.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
3.6 61.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
3.3 49.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
2.8 62.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
2.6 82.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
2.4 148.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
2.4 152.6 REACTOME G1 PHASE Genes involved in G1 Phase
2.3 356.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
2.2 15.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
2.2 17.5 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
1.9 65.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
1.8 23.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.8 18.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.7 39.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.7 59.7 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
1.6 55.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.6 7.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
1.5 31.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
1.5 54.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
1.4 10.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.4 61.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
1.4 143.9 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
1.4 103.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
1.3 12.9 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
1.3 8.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.2 34.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.2 24.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
1.2 17.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
1.1 28.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.1 19.8 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.1 24.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
1.1 25.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.1 22.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.1 26.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.0 11.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.9 11.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.9 1.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.9 21.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.9 68.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.9 27.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.8 28.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.8 21.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.8 9.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.8 15.6 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.8 12.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.8 35.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.8 6.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.8 27.1 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.8 26.9 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.8 29.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.7 5.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.7 5.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.6 26.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.6 3.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.6 15.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.6 40.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6 7.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.6 3.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.5 6.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 12.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.5 15.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.5 5.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.5 2.4 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.5 68.6 REACTOME TRANSLATION Genes involved in Translation
0.5 29.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 55.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.4 4.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.4 10.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.4 7.9 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.4 4.6 REACTOME OPSINS Genes involved in Opsins
0.4 3.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.4 5.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 3.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4 16.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 6.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 4.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 3.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.3 4.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3 11.7 REACTOME METABOLISM OF NUCLEOTIDES Genes involved in Metabolism of nucleotides
0.3 7.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 7.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 9.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.3 41.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 10.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 2.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 4.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 10.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 1.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.2 5.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 1.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 4.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 4.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 1.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 10.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 2.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 0.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 2.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 5.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 4.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 6.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 5.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.4 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.6 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation