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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TLX2

Z-value: 1.35

Motif logo

Transcription factors associated with TLX2

Gene Symbol Gene ID Gene Info
ENSG00000115297.9 T cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TLX2hg19_v2_chr2_+_74741569_747416200.545.6e-18Click!

Activity profile of TLX2 motif

Sorted Z-values of TLX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_88323218 22.12 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr8_-_27941380 16.47 ENST00000413272.2
ENST00000341513.6
nuclear GTPase, germinal center associated
chr16_+_58283814 14.81 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chr12_-_91572278 13.53 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chr3_-_122283100 13.09 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr2_+_17721920 12.62 ENST00000295156.4
visinin-like 1
chr3_-_58572760 12.56 ENST00000447756.2
family with sequence similarity 107, member A
chr1_-_156399184 12.10 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chr11_-_22851367 12.04 ENST00000354193.4
small VCP/p97-interacting protein
chr14_+_23299088 12.01 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
mitochondrial ribosomal protein L52
chrX_+_38420783 11.67 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
tetraspanin 7
chr19_-_37019562 11.65 ENST00000523638.1
zinc finger protein 260
chr19_-_37019136 11.64 ENST00000592282.1
zinc finger protein 260
chr19_-_3028354 11.50 ENST00000586422.1
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr8_+_80523962 11.12 ENST00000518491.1
stathmin-like 2
chr18_-_13726510 11.07 ENST00000322247.3
ENST00000592976.1
ENST00000402563.1
ENST00000591269.1
family with sequence similarity 210, member A
chr1_-_161279749 10.86 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
myelin protein zero
chr1_+_33005020 10.77 ENST00000373510.4
ENST00000316459.4
zinc finger and BTB domain containing 8A
chr12_-_99038732 10.42 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBKB interacting protein
chr1_+_153330322 10.27 ENST00000368738.3
S100 calcium binding protein A9
chr6_-_32498046 9.97 ENST00000374975.3
major histocompatibility complex, class II, DR beta 5
chr20_-_47894936 9.68 ENST00000371754.4
zinc finger, NFX1-type containing 1
chrX_+_56259316 9.43 ENST00000468660.1
Kruppel-like factor 8
chr1_+_16062820 9.29 ENST00000294454.5
solute carrier family 25, member 34
chr8_+_80523321 9.20 ENST00000518111.1
stathmin-like 2
chr14_-_106622419 9.14 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr17_-_27278304 9.07 ENST00000577226.1
PHD finger protein 12
chr16_-_3306587 8.99 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
Mediterranean fever
chr1_-_153363452 8.91 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr4_-_17812309 8.76 ENST00000382247.1
ENST00000536863.1
DDB1 and CUL4 associated factor 16
chrX_+_38420623 8.75 ENST00000378482.2
tetraspanin 7
chr8_-_27115931 8.48 ENST00000523048.1
stathmin-like 4
chr17_-_617949 8.39 ENST00000401468.3
ENST00000574029.1
ENST00000291074.5
ENST00000571805.1
ENST00000437048.2
ENST00000446250.2
vacuolar protein sorting 53 homolog (S. cerevisiae)
chr10_+_76871353 8.26 ENST00000542569.1
sterile alpha motif domain containing 8
chr2_+_149632783 8.23 ENST00000435030.1
kinesin family member 5C
chr18_+_77439775 8.11 ENST00000299543.7
ENST00000075430.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr14_+_101292445 8.06 ENST00000429159.2
ENST00000520714.1
ENST00000522771.2
ENST00000424076.3
ENST00000423456.1
ENST00000521404.1
ENST00000556736.1
ENST00000451743.2
ENST00000398518.2
ENST00000554639.1
ENST00000452120.2
ENST00000519709.1
ENST00000412736.2
maternally expressed 3 (non-protein coding)
chr3_-_170303845 7.98 ENST00000231706.5
solute carrier family 7, member 14
chr12_+_113229737 7.93 ENST00000551052.1
ENST00000415485.3
rabphilin 3A homolog (mouse)
chr20_+_42839600 7.78 ENST00000439943.1
ENST00000437730.1
OSER1 antisense RNA 1 (head to head)
chr1_+_155829286 7.78 ENST00000368324.4
synaptotagmin XI
chr8_-_27115903 7.67 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chrX_-_38186811 7.42 ENST00000318842.7
retinitis pigmentosa GTPase regulator
chr20_+_42839722 7.23 ENST00000442383.1
ENST00000435163.1
OSER1 antisense RNA 1 (head to head)
chr12_-_16759711 7.21 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr4_+_156680153 7.11 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
guanylate cyclase 1, soluble, beta 3
chr11_-_133826852 7.03 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr11_-_64510409 7.02 ENST00000394429.1
ENST00000394428.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr4_+_156680518 7.01 ENST00000513437.1
guanylate cyclase 1, soluble, beta 3
chr1_-_38157877 7.00 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
chromosome 1 open reading frame 109
chr10_+_76871454 7.00 ENST00000372687.4
sterile alpha motif domain containing 8
chrX_+_76709648 6.92 ENST00000439435.1
fibroblast growth factor 16
chr17_-_46667594 6.88 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
homeobox B3
chr3_+_38537960 6.82 ENST00000453767.1
endo/exonuclease (5'-3'), endonuclease G-like
chr10_-_115933942 6.74 ENST00000369285.3
ENST00000369287.3
ENST00000369286.1
chromosome 10 open reading frame 118
chr14_+_65171099 6.73 ENST00000247226.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr16_+_29674540 6.51 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
sialophorin
quinolinate phosphoribosyltransferase
chr17_-_79139817 6.46 ENST00000326724.4
apoptosis-associated tyrosine kinase
chr17_-_46667628 6.38 ENST00000498678.1
homeobox B3
chr1_-_151762943 6.38 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
tudor and KH domain containing
chr19_+_17186577 6.37 ENST00000595618.1
ENST00000594824.1
myosin IXB
chr8_-_27630102 6.26 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
coiled-coil domain containing 25
chr14_+_65171315 6.24 ENST00000394691.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr15_+_91643442 6.21 ENST00000394232.1
synaptic vesicle glycoprotein 2B
chr1_+_92764522 6.18 ENST00000610020.1
RNA polymerase II associated protein 2
chr10_-_47173994 6.16 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr15_+_75118888 6.11 ENST00000395018.4
complexin 3
chr2_+_10183651 6.03 ENST00000305883.1
Kruppel-like factor 11
chr11_+_113930291 5.99 ENST00000335953.4
zinc finger and BTB domain containing 16
chr6_-_6007200 5.96 ENST00000244766.2
neuritin 1
chrX_-_73512411 5.95 ENST00000602576.1
ENST00000429124.1
FTX transcript, XIST regulator (non-protein coding)
chr10_-_124768300 5.94 ENST00000368886.5
IKAROS family zinc finger 5 (Pegasus)
chr10_-_44880491 5.80 ENST00000374426.2
ENST00000395795.4
ENST00000395794.2
ENST00000374429.2
ENST00000395793.3
ENST00000343575.6
chemokine (C-X-C motif) ligand 12
chr20_-_47894569 5.70 ENST00000371744.1
ENST00000371752.1
ENST00000396105.1
zinc finger, NFX1-type containing 1
chr3_-_49158312 5.53 ENST00000398892.3
ENST00000453664.1
ENST00000398888.2
ubiquitin specific peptidase 19
chr10_+_47746929 5.52 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
annexin A8-like 2
Protein LOC100996760
chr1_+_36789335 5.50 ENST00000373137.2
RP11-268J15.5
chr21_+_34398153 5.49 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
oligodendrocyte lineage transcription factor 2
chr16_+_6069586 5.48 ENST00000547372.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_-_89918522 5.48 ENST00000529983.2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr19_+_840963 5.45 ENST00000234347.5
proteinase 3
chr9_-_79520989 5.39 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr1_+_15764931 5.39 ENST00000375949.4
ENST00000375943.2
chymotrypsin C (caldecrin)
chr12_-_71182695 5.39 ENST00000342084.4
protein tyrosine phosphatase, receptor type, R
chr20_+_44746885 5.37 ENST00000372285.3
CD40 molecule, TNF receptor superfamily member 5
chr17_-_74722672 5.34 ENST00000397625.4
ENST00000445478.2
jumonji domain containing 6
chr4_+_156680143 5.31 ENST00000505154.1
guanylate cyclase 1, soluble, beta 3
chr4_+_165675269 5.28 ENST00000507311.1
RP11-294O2.2
chr3_-_49158218 5.26 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
ubiquitin specific peptidase 19
chr2_+_219433281 5.19 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr14_-_21270561 5.07 ENST00000412779.2
ribonuclease, RNase A family, 1 (pancreatic)
chr3_+_115342349 5.06 ENST00000393780.3
growth associated protein 43
chr8_+_26435359 5.03 ENST00000311151.5
dihydropyrimidinase-like 2
chr7_-_99573677 5.03 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr19_-_6767516 5.02 ENST00000245908.6
SH2 domain containing 3A
chr1_-_32169761 5.02 ENST00000271069.6
collagen, type XVI, alpha 1
chr19_-_52133588 4.96 ENST00000570106.2
sialic acid binding Ig-like lectin 5
chr2_-_175869936 4.94 ENST00000409900.3
chimerin 1
chr19_-_22034809 4.93 ENST00000594012.1
ENST00000595461.1
ENST00000596899.1
zinc finger protein 43
chr16_+_1383602 4.91 ENST00000426824.3
ENST00000397488.2
ENST00000562208.1
ENST00000568887.1
BAI1-associated protein 3
chr1_-_31230650 4.88 ENST00000294507.3
lysosomal protein transmembrane 5
chr11_-_1036706 4.87 ENST00000421673.2
mucin 6, oligomeric mucus/gel-forming
chr19_+_10541462 4.83 ENST00000293683.5
phosphodiesterase 4A, cAMP-specific
chr10_+_124768482 4.82 ENST00000368869.4
ENST00000358776.4
acyl-CoA dehydrogenase, short/branched chain
chr10_+_64133934 4.81 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
zinc finger protein 365
chr7_-_99573640 4.79 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr2_+_111878483 4.76 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2-like 11 (apoptosis facilitator)
chr9_-_115480303 4.75 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INTS3 and NABP interacting protein
chrX_-_73512177 4.73 ENST00000603672.1
ENST00000418855.1
FTX transcript, XIST regulator (non-protein coding)
chr2_-_62733476 4.72 ENST00000335390.5
transmembrane protein 17
chr6_-_49712147 4.72 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr20_+_44746939 4.70 ENST00000372276.3
CD40 molecule, TNF receptor superfamily member 5
chr2_+_10184302 4.68 ENST00000440320.1
ENST00000535335.1
Kruppel-like factor 11
chr15_+_81475047 4.67 ENST00000559388.1
interleukin 16
chr12_+_56732658 4.64 ENST00000228534.4
interleukin 23, alpha subunit p19
chr4_+_156588806 4.64 ENST00000513574.1
guanylate cyclase 1, soluble, alpha 3
chr20_-_1472029 4.64 ENST00000359801.3
signal-regulatory protein beta 2
chr12_+_32655048 4.60 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr7_+_24324726 4.58 ENST00000405982.1
neuropeptide Y
chr1_-_32169920 4.57 ENST00000373672.3
ENST00000373668.3
collagen, type XVI, alpha 1
chr3_-_194090460 4.56 ENST00000428839.1
ENST00000347624.3
leucine rich repeat containing 15
chr16_+_6069664 4.56 ENST00000422070.4
RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_-_39421377 4.56 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
seryl-tRNA synthetase 2, mitochondrial
chr1_+_9711781 4.54 ENST00000536656.1
ENST00000377346.4
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr3_+_46412345 4.52 ENST00000292303.4
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr1_-_235813290 4.49 ENST00000391854.2
guanine nucleotide binding protein (G protein), gamma 4
chr11_+_128563652 4.49 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_18957500 4.48 ENST00000375375.3
paired box 7
chr7_-_135433460 4.48 ENST00000415751.1
family with sequence similarity 180, member A
chr14_-_21270995 4.48 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr10_-_90712520 4.44 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr19_+_16435625 4.40 ENST00000248071.5
ENST00000592003.1
Kruppel-like factor 2
chr14_+_76618242 4.38 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
G patch domain containing 2-like
chr1_+_119957554 4.38 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr12_+_69864129 4.36 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
fibroblast growth factor receptor substrate 2
chr3_+_138067666 4.33 ENST00000475711.1
ENST00000464896.1
muscle RAS oncogene homolog
chr6_+_167525277 4.30 ENST00000400926.2
chemokine (C-C motif) receptor 6
chr1_+_207627697 4.30 ENST00000458541.2
complement component (3d/Epstein Barr virus) receptor 2
chr19_-_51920952 4.26 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
sialic acid binding Ig-like lectin 10
chr8_+_86376081 4.26 ENST00000285379.5
carbonic anhydrase II
chr12_-_95611149 4.23 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FYVE, RhoGEF and PH domain containing 6
chr8_+_38758737 4.23 ENST00000521746.1
ENST00000420274.1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr19_+_52264449 4.20 ENST00000599326.1
ENST00000598953.1
formyl peptide receptor 2
chr1_+_207627575 4.19 ENST00000367058.3
ENST00000367057.3
ENST00000367059.3
complement component (3d/Epstein Barr virus) receptor 2
chr4_-_36246060 4.13 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_-_18666360 4.11 ENST00000286485.8
pleckstrin and Sec7 domain containing 3
chr8_-_82024290 4.11 ENST00000220597.4
phosphoprotein associated with glycosphingolipid microdomains 1
chr5_-_107703556 4.11 ENST00000496714.1
F-box and leucine-rich repeat protein 17
chr20_+_3024266 4.10 ENST00000245983.2
ENST00000359100.2
ENST00000359987.1
gonadotropin-releasing hormone 2
chr10_+_48255253 4.09 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
annexin A8
Protein LOC100996760
chr2_-_175870085 4.02 ENST00000409156.3
chimerin 1
chr21_-_38639601 3.98 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
Down syndrome critical region gene 3
chr3_-_48956818 3.95 ENST00000408959.2
ariadne homolog 2 opposite strand
chr4_-_90758118 3.95 ENST00000420646.2
synuclein, alpha (non A4 component of amyloid precursor)
chr19_-_52150053 3.92 ENST00000599649.1
ENST00000429354.3
ENST00000360844.6
ENST00000222107.4
SIGLEC5
sialic acid binding Ig-like lectin 14
sialic acid binding Ig-like lectin 5
chr4_+_2814011 3.90 ENST00000502260.1
ENST00000435136.2
SH3-domain binding protein 2
chr8_+_27183033 3.88 ENST00000420218.2
protein tyrosine kinase 2 beta
chr11_+_117947782 3.87 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
transmembrane protease, serine 4
chr12_+_50794730 3.86 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
La ribonucleoprotein domain family, member 4
chr10_+_17794251 3.84 ENST00000377495.1
ENST00000338221.5
transmembrane protein 236
chr1_+_152881014 3.84 ENST00000368764.3
ENST00000392667.2
involucrin
chr10_+_73975742 3.80 ENST00000299381.4
anaphase promoting complex subunit 16
chr1_+_1370903 3.80 ENST00000338660.5
ENST00000404702.3
ENST00000476993.1
ENST00000471398.1
von Willebrand factor A domain containing 1
chr4_+_2813946 3.75 ENST00000442312.2
SH3-domain binding protein 2
chr11_-_8190534 3.73 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
RIC3 acetylcholine receptor chaperone
chr17_+_7211280 3.68 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
eukaryotic translation initiation factor 5A
chr12_-_33049690 3.67 ENST00000070846.6
ENST00000340811.4
plakophilin 2
chrX_+_153626571 3.66 ENST00000424325.2
ribosomal protein L10
chr8_+_27182862 3.65 ENST00000521164.1
ENST00000346049.5
protein tyrosine kinase 2 beta
chr1_-_36947120 3.64 ENST00000361632.4
colony stimulating factor 3 receptor (granulocyte)
chr15_-_65360450 3.62 ENST00000220062.4
RAS-like, family 12
chr12_+_133563026 3.62 ENST00000540238.1
ENST00000328654.5
ENST00000544181.1
zinc finger protein 26
chr19_-_12833361 3.54 ENST00000592287.1
transportin 2
chr2_-_239197201 3.54 ENST00000254658.3
period circadian clock 2
chr4_+_113970772 3.53 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr12_-_120763739 3.52 ENST00000549767.1
phospholipase A2, group IB (pancreas)
chr6_+_106546808 3.49 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr19_+_2389784 3.48 ENST00000332578.3
transmembrane protease, serine 9
chr6_-_74363803 3.48 ENST00000355773.5
solute carrier family 17 (acidic sugar transporter), member 5
chr22_+_42229100 3.44 ENST00000361204.4
sterol regulatory element binding transcription factor 2
chr15_-_35047166 3.44 ENST00000290374.4
gap junction protein, delta 2, 36kDa
chr8_-_134584092 3.43 ENST00000522652.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr12_+_12938541 3.42 ENST00000356591.4
apolipoprotein L domain containing 1
chr3_-_46608010 3.40 ENST00000395905.3
leucine rich repeat containing 2
chr4_-_90758227 3.39 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
synuclein, alpha (non A4 component of amyloid precursor)
chr8_+_133879193 3.38 ENST00000377869.1
ENST00000220616.4
thyroglobulin
chr12_+_6494285 3.37 ENST00000541102.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr3_-_105587879 3.37 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr19_+_52264104 3.36 ENST00000340023.6
formyl peptide receptor 2
chr14_-_24711470 3.31 ENST00000559969.1
TERF1 (TRF1)-interacting nuclear factor 2
chr21_-_38639813 3.31 ENST00000309117.6
ENST00000398998.1
Down syndrome critical region gene 3
chr1_+_50575292 3.30 ENST00000371821.1
ENST00000371819.1
ELAV like neuron-specific RNA binding protein 4
chr19_-_51920873 3.28 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
sialic acid binding Ig-like lectin 10
chr12_-_48119301 3.28 ENST00000545824.2
ENST00000422538.3
endonuclease, polyU-specific
chr19_+_35783028 3.27 ENST00000600291.1
ENST00000392213.3
myelin associated glycoprotein
chr3_-_45838011 3.27 ENST00000358525.4
ENST00000413781.1
solute carrier family 6 (proline IMINO transporter), member 20
chr2_-_228497888 3.26 ENST00000264387.4
ENST00000409066.1
chromosome 2 open reading frame 83
chr22_+_50925213 3.26 ENST00000395733.3
ENST00000216075.6
ENST00000395732.3
myo-inositol oxygenase
chr4_+_78078304 3.25 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
cyclin G2
chr5_+_79331164 3.23 ENST00000350881.2
thrombospondin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
5.1 20.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
4.8 14.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
4.0 12.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
3.4 10.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
3.0 9.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
2.7 13.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
2.6 7.8 GO:1905154 negative regulation of membrane invagination(GO:1905154)
2.4 4.8 GO:0052042 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
2.2 13.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.9 15.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.9 7.5 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
1.8 5.5 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
1.8 5.5 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.6 6.5 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
1.5 4.6 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
1.5 8.9 GO:0032119 sequestering of zinc ion(GO:0032119)
1.5 4.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.5 7.3 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.5 4.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
1.4 8.7 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
1.4 10.1 GO:0033590 response to cobalamin(GO:0033590)
1.4 4.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.4 4.3 GO:0042938 dipeptide transport(GO:0042938)
1.4 4.1 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
1.4 1.4 GO:2000196 positive regulation of female gonad development(GO:2000196)
1.3 3.8 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.2 7.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.2 3.5 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.2 5.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
1.1 4.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.1 13.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.1 4.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
1.1 3.3 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.1 16.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.0 3.0 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
1.0 2.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.0 6.9 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
1.0 3.0 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
1.0 10.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.0 2.9 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.9 4.6 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.9 2.8 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.9 3.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.9 2.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.9 5.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.9 0.9 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.9 5.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.9 3.5 GO:0044240 activation of phospholipase A2 activity(GO:0032431) multicellular organism lipid catabolic process(GO:0044240)
0.9 2.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.9 3.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.8 5.6 GO:0015824 proline transport(GO:0015824)
0.8 6.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.8 2.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.8 2.4 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.8 2.3 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.8 4.6 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.8 2.3 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.8 5.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.7 3.7 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.7 4.4 GO:0090131 mesenchyme migration(GO:0090131)
0.7 1.5 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.7 5.1 GO:0016198 axon choice point recognition(GO:0016198)
0.7 3.5 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.7 2.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.7 2.8 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.7 4.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.7 2.1 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.7 2.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.7 4.6 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.6 4.5 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.6 11.6 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.6 6.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.6 3.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.6 7.7 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.6 4.6 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.5 18.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.5 2.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.5 4.5 GO:0015705 iodide transport(GO:0015705)
0.5 2.9 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.5 2.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.5 2.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.5 3.8 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.5 0.9 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.5 6.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.5 2.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.5 1.9 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.5 3.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5 3.2 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.4 2.7 GO:1902715 secretory granule localization(GO:0032252) positive regulation of interferon-gamma secretion(GO:1902715)
0.4 0.9 GO:0048867 stem cell fate determination(GO:0048867)
0.4 1.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.4 1.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.4 0.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 2.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.4 3.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.4 11.0 GO:0098743 cell aggregation(GO:0098743)
0.4 7.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.4 1.9 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.4 1.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.4 1.5 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.4 3.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.4 9.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.4 4.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.4 16.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.4 2.1 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.4 2.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 1.0 GO:0001694 histamine biosynthetic process(GO:0001694)
0.3 13.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.3 2.3 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.3 3.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 2.3 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.3 4.4 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.3 0.9 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 3.4 GO:0042118 endothelial cell activation(GO:0042118)
0.3 3.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 1.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.3 7.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 1.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.3 4.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 0.8 GO:0061056 sclerotome development(GO:0061056)
0.3 0.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.3 2.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 4.7 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.7 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.2 3.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 5.6 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 1.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 5.7 GO:0048485 sympathetic nervous system development(GO:0048485)
0.2 1.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 11.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.2 4.5 GO:0035855 megakaryocyte development(GO:0035855)
0.2 13.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 4.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 2.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 7.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.2 7.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 5.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 4.1 GO:0032011 ARF protein signal transduction(GO:0032011)
0.2 1.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.2 1.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 1.0 GO:1903059 positive regulation of lipoprotein metabolic process(GO:0050747) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.2 3.8 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.2 1.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 3.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 2.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 2.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 8.0 GO:0032456 endocytic recycling(GO:0032456)
0.2 5.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.2 2.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 4.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.2 0.8 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 1.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 10.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 9.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 2.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 3.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.9 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 2.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 1.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 2.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 9.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 22.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 6.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 3.3 GO:0046174 polyol catabolic process(GO:0046174)
0.1 1.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.9 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1 3.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 6.4 GO:0042073 intraciliary transport(GO:0042073)
0.1 9.2 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 5.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 14.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 1.0 GO:0070995 NADPH oxidation(GO:0070995)
0.1 2.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 2.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 2.4 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.1 2.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 10.6 GO:0031295 T cell costimulation(GO:0031295)
0.1 2.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 3.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 2.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.7 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 2.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 1.2 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.1 11.1 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 6.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.0 GO:0015074 DNA integration(GO:0015074)
0.1 2.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 2.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 0.4 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 2.6 GO:0010107 potassium ion import(GO:0010107)
0.1 3.5 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.1 2.9 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.2 GO:0010193 response to ozone(GO:0010193) negative regulation of interleukin-13 production(GO:0032696)
0.1 4.0 GO:0042100 B cell proliferation(GO:0042100)
0.1 1.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 1.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 3.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 1.1 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.5 GO:0051601 exocyst localization(GO:0051601)
0.1 0.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 7.3 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 1.6 GO:0003016 respiratory system process(GO:0003016)
0.1 1.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.1 1.8 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 1.3 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 11.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 1.8 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 3.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 1.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 3.6 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 3.5 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 1.8 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 2.0 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 4.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 6.1 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 2.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 1.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 5.5 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 3.3 GO:0007586 digestion(GO:0007586)
0.0 3.3 GO:0000075 cell cycle checkpoint(GO:0000075)
0.0 0.4 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0061325 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.9 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 1.7 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 1.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
2.1 8.4 GO:1990745 EARP complex(GO:1990745)
1.8 16.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.6 7.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.3 6.4 GO:0071546 pi-body(GO:0071546)
1.3 10.1 GO:0043196 varicosity(GO:0043196)
1.2 9.6 GO:0005593 FACIT collagen trimer(GO:0005593)
1.2 4.7 GO:0070876 SOSS complex(GO:0070876)
1.1 4.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.1 3.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
1.0 13.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.0 24.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.8 17.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.8 3.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.8 2.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.8 7.1 GO:0016013 syntrophin complex(GO:0016013)
0.7 5.1 GO:0032584 growth cone membrane(GO:0032584)
0.7 5.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.7 2.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.7 1.3 GO:0033186 CAF-1 complex(GO:0033186)
0.6 1.9 GO:0097447 dendritic tree(GO:0097447)
0.6 7.0 GO:0060077 inhibitory synapse(GO:0060077)
0.6 8.2 GO:0035253 ciliary rootlet(GO:0035253)
0.6 14.8 GO:0034451 centriolar satellite(GO:0034451)
0.6 2.3 GO:0031673 H zone(GO:0031673)
0.5 3.0 GO:1990130 Iml1 complex(GO:1990130)
0.5 3.0 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5 7.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 1.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.5 3.3 GO:0070852 cell body fiber(GO:0070852)
0.4 15.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 1.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 4.7 GO:0036038 MKS complex(GO:0036038)
0.4 1.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 9.1 GO:0016580 Sin3 complex(GO:0016580)
0.4 4.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.4 4.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 2.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.3 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.3 6.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 2.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 1.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 3.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 2.6 GO:0097486 multivesicular body lumen(GO:0097486)
0.3 3.7 GO:0005642 annulate lamellae(GO:0005642)
0.3 12.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 9.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 8.1 GO:0051233 spindle midzone(GO:0051233)
0.3 3.0 GO:0030897 HOPS complex(GO:0030897)
0.2 7.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 3.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 1.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 2.2 GO:0071953 elastic fiber(GO:0071953)
0.2 17.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 7.8 GO:0042629 mast cell granule(GO:0042629)
0.2 1.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 3.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 33.6 GO:0030426 growth cone(GO:0030426)
0.2 5.0 GO:0031143 pseudopodium(GO:0031143)
0.2 3.4 GO:0005922 connexon complex(GO:0005922)
0.2 2.0 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.2 9.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 9.4 GO:0016235 aggresome(GO:0016235)
0.2 13.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 11.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 3.0 GO:0044447 axoneme part(GO:0044447)
0.1 12.3 GO:0035580 specific granule lumen(GO:0035580)
0.1 3.8 GO:0001533 cornified envelope(GO:0001533)
0.1 2.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 3.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 6.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 11.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 16.0 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 3.8 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 9.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 9.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 5.1 GO:0043235 receptor complex(GO:0043235)
0.1 1.4 GO:0097342 ripoptosome(GO:0097342)
0.1 4.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.6 GO:0001726 ruffle(GO:0001726)
0.1 4.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 3.1 GO:0005902 microvillus(GO:0005902)
0.1 1.9 GO:0005901 caveola(GO:0005901)
0.1 4.0 GO:0030315 T-tubule(GO:0030315)
0.1 4.9 GO:0005884 actin filament(GO:0005884)
0.1 0.5 GO:0005921 gap junction(GO:0005921)
0.1 1.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.5 GO:0031526 brush border membrane(GO:0031526)
0.0 2.2 GO:0045095 keratin filament(GO:0045095)
0.0 4.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0005844 polysome(GO:0005844)
0.0 2.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 3.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 2.8 GO:0043204 perikaryon(GO:0043204)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 4.0 GO:0030424 axon(GO:0030424)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.8 GO:0098793 presynapse(GO:0098793)
0.0 2.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 26.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 4.4 GO:0043005 neuron projection(GO:0043005)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
5.1 15.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
2.9 14.3 GO:0008420 CTD phosphatase activity(GO:0008420)
2.5 7.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
2.2 6.5 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
1.9 7.6 GO:0005124 scavenger receptor binding(GO:0005124)
1.7 5.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.6 9.5 GO:0004522 ribonuclease A activity(GO:0004522)
1.5 4.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.5 7.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.5 4.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
1.3 13.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
1.1 3.3 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.1 5.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
1.0 5.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.0 2.9 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
1.0 24.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.9 5.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.9 5.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.9 3.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.8 3.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.8 2.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.8 8.5 GO:0004875 complement receptor activity(GO:0004875)
0.7 8.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.7 7.9 GO:0008430 selenium binding(GO:0008430)
0.7 5.0 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.7 6.4 GO:0048495 Roundabout binding(GO:0048495)
0.7 8.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.7 2.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.7 2.0 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.6 4.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.6 3.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.6 3.1 GO:0051373 FATZ binding(GO:0051373)
0.6 1.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.6 1.8 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.6 18.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.6 3.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.6 2.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 8.2 GO:0033691 sialic acid binding(GO:0033691)
0.5 13.1 GO:0070403 NAD+ binding(GO:0070403)
0.5 9.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.5 4.3 GO:0004064 arylesterase activity(GO:0004064)
0.5 9.8 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.5 5.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.5 3.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.5 3.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 5.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.5 6.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.5 1.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5 4.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 12.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.4 2.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 10.2 GO:0017166 vinculin binding(GO:0017166)
0.4 2.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.4 5.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 6.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.4 5.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 5.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 17.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.4 5.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 4.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 10.3 GO:0042605 peptide antigen binding(GO:0042605)
0.3 5.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 0.9 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.3 1.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 4.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 2.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 8.8 GO:0043236 laminin binding(GO:0043236)
0.3 2.6 GO:0004969 histamine receptor activity(GO:0004969)
0.3 3.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.3 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 3.7 GO:0019215 intermediate filament binding(GO:0019215) alpha-catenin binding(GO:0045294)
0.3 1.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.3 2.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 6.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 9.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 1.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 3.9 GO:0045499 chemorepellent activity(GO:0045499)
0.3 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 6.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.3 0.8 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 13.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 5.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 2.4 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 6.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 2.6 GO:0019843 rRNA binding(GO:0019843)
0.2 7.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 2.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 3.5 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 2.3 GO:0045545 syndecan binding(GO:0045545)
0.2 3.4 GO:0005243 gap junction channel activity(GO:0005243)
0.2 5.5 GO:0071837 HMG box domain binding(GO:0071837)
0.2 21.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 0.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.2 3.5 GO:0030955 potassium ion binding(GO:0030955)
0.2 2.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.4 GO:0097643 amylin receptor activity(GO:0097643)
0.2 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 3.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 6.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 1.9 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 9.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 24.6 GO:0005178 integrin binding(GO:0005178)
0.2 9.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 3.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 1.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 4.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 4.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 3.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.1 3.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 3.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 1.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.8 GO:0003774 motor activity(GO:0003774)
0.1 2.0 GO:0031005 filamin binding(GO:0031005)
0.1 8.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 2.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 5.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 6.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 4.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 28.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.9 GO:0032356 oxidized DNA binding(GO:0032356)
0.1 1.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 8.8 GO:0005179 hormone activity(GO:0005179)
0.1 0.7 GO:0042301 phosphate ion binding(GO:0042301)
0.1 3.3 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 2.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.0 GO:0019864 IgG binding(GO:0019864)
0.1 2.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.0 GO:0043422 protein kinase B binding(GO:0043422)
0.1 13.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.8 GO:0031402 sodium ion binding(GO:0031402)
0.1 5.1 GO:0035064 methylated histone binding(GO:0035064)
0.1 5.0 GO:0015297 antiporter activity(GO:0015297)
0.1 1.1 GO:0032052 bile acid binding(GO:0032052)
0.1 2.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 2.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 2.4 GO:0030332 cyclin binding(GO:0030332)
0.1 72.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 2.9 GO:0002039 p53 binding(GO:0002039)
0.1 1.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 2.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 3.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 3.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.0 GO:0017022 myosin binding(GO:0017022)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.7 GO:0030507 spectrin binding(GO:0030507)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 4.6 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 7.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.6 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 2.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 19.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 14.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 15.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 13.5 PID CD40 PATHWAY CD40/CD40L signaling
0.3 2.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 4.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 9.7 PID RAS PATHWAY Regulation of Ras family activation
0.2 2.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 3.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 5.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 6.5 PID IL23 PATHWAY IL23-mediated signaling events
0.1 4.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 21.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 8.9 PID SHP2 PATHWAY SHP2 signaling
0.1 7.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 4.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 4.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 4.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 6.4 PID FOXO PATHWAY FoxO family signaling
0.1 3.5 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.3 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 3.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 6.0 PID CMYB PATHWAY C-MYB transcription factor network
0.1 7.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.7 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.9 PID ATR PATHWAY ATR signaling pathway
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 10.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.1 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.6 1.9 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.6 11.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.5 5.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.5 13.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 10.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 9.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.5 25.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.4 2.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.3 14.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 4.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 4.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 4.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 6.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 4.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 7.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.3 9.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 3.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 7.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 7.2 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 2.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 3.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 4.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 4.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 4.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 3.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 3.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 3.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.9 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.2 4.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 3.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 10.0 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.2 4.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 1.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 11.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 3.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 5.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 8.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 5.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 4.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 9.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 15.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 7.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 4.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 4.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 7.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 3.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 3.3 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.1 11.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.3 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 14.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.9 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 1.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation