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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for TP63

Z-value: 1.53

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Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
ENSG00000073282.8 tumor protein p63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189507523_189507590-0.441.5e-11Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_63448973 30.03 ENST00000462430.1
ribosomal protein S27-like
chr12_-_122712038 30.02 ENST00000413918.1
ENST00000443649.3
diablo, IAP-binding mitochondrial protein
chr6_-_30712313 28.21 ENST00000376377.2
ENST00000259874.5
immediate early response 3
chrX_-_153602991 23.39 ENST00000369850.3
ENST00000422373.1
filamin A, alpha
chr2_-_151344172 22.35 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr1_+_236558694 22.34 ENST00000359362.5
EDAR-associated death domain
chr12_-_15942503 21.71 ENST00000281172.5
epidermal growth factor receptor pathway substrate 8
chr5_+_162864575 21.47 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr17_+_49230897 18.86 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr19_+_49497121 18.13 ENST00000413176.2
RuvB-like AAA ATPase 2
chr20_+_35234137 18.00 ENST00000344795.3
ENST00000373852.5
chromosome 20 open reading frame 24
chr5_+_115420688 17.86 ENST00000274458.4
COMM domain containing 10
chr20_+_48807351 17.63 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr11_+_832804 17.40 ENST00000397420.3
ENST00000525718.1
CD151 molecule (Raph blood group)
chr20_+_35234223 17.40 ENST00000342422.3
chromosome 20 open reading frame 24
chr2_+_198365122 16.52 ENST00000604458.1
HSPE1-MOB4 readthrough
chr19_+_48824711 16.12 ENST00000599704.1
epithelial membrane protein 3
chr19_+_18496957 15.45 ENST00000252809.3
growth differentiation factor 15
chr16_+_57653989 15.34 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr2_-_47168850 14.86 ENST00000409207.1
multiple coagulation factor deficiency 2
chr6_+_10748019 14.64 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
synaptonemal complex protein 2-like
transmembrane protein 14B
chr15_-_63449663 14.62 ENST00000439025.1
ribosomal protein S27-like
chr3_+_184080387 14.39 ENST00000455712.1
polymerase (RNA) II (DNA directed) polypeptide H
chr2_+_217524323 14.21 ENST00000456764.1
insulin-like growth factor binding protein 2, 36kDa
chr16_+_57653854 13.91 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
G protein-coupled receptor 56
chr6_+_10747986 13.79 ENST00000379542.5
transmembrane protein 14B
chr8_+_22437965 13.55 ENST00000409141.1
ENST00000265810.4
PDZ and LIM domain 2 (mystique)
chr7_+_100466433 13.18 ENST00000429658.1
thyroid hormone receptor interactor 6
chr8_-_49833978 12.72 ENST00000020945.1
snail family zinc finger 2
chr17_-_79818354 12.60 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
prolyl 4-hydroxylase, beta polypeptide
chr2_-_47168906 12.58 ENST00000444761.2
ENST00000409147.1
multiple coagulation factor deficiency 2
chr22_-_36924944 12.25 ENST00000405442.1
ENST00000402116.1
eukaryotic translation initiation factor 3, subunit D
chr1_-_209824643 12.15 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr15_-_72523924 11.83 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
pyruvate kinase, muscle
chr2_+_198365095 11.79 ENST00000409468.1
heat shock 10kDa protein 1
chr17_-_26662440 11.71 ENST00000578122.1
intraflagellar transport 20 homolog (Chlamydomonas)
chr1_+_158979686 11.71 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr5_+_170814803 11.66 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr22_-_36925186 11.54 ENST00000541106.1
ENST00000455547.1
ENST00000432675.1
eukaryotic translation initiation factor 3, subunit D
chr1_+_158979680 11.50 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr11_-_14541872 11.46 ENST00000419365.2
ENST00000530457.1
ENST00000532256.1
ENST00000533068.1
proteasome (prosome, macropain) subunit, alpha type, 1
chr1_+_38158090 11.45 ENST00000373055.1
ENST00000327331.2
cell division cycle associated 8
chr22_+_39378346 11.34 ENST00000407298.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr1_+_158979792 11.29 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr19_+_42364460 11.14 ENST00000593863.1
ribosomal protein S19
chr5_-_179051579 10.94 ENST00000505811.1
ENST00000515714.1
ENST00000513225.1
ENST00000503664.1
ENST00000356731.5
ENST00000523137.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chrX_+_150148976 10.89 ENST00000419110.1
high mobility group box 3
chr3_+_184081213 10.69 ENST00000429568.1
polymerase (RNA) II (DNA directed) polypeptide H
chr3_-_149375783 10.52 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WW domain containing transcription regulator 1
chr8_-_117778494 10.45 ENST00000276682.4
eukaryotic translation initiation factor 3, subunit H
chr2_-_178257401 10.44 ENST00000464747.1
nuclear factor, erythroid 2-like 2
chr14_+_52456193 10.39 ENST00000261700.3
chromosome 14 open reading frame 166
chr14_+_52456327 10.34 ENST00000556760.1
chromosome 14 open reading frame 166
chr15_-_66816853 10.26 ENST00000568588.1
ribosomal protein L4
chr2_+_178257372 10.01 ENST00000264167.4
ENST00000409888.1
alkylglycerone phosphate synthase
chr3_+_184081175 9.91 ENST00000452961.1
ENST00000296223.3
polymerase (RNA) II (DNA directed) polypeptide H
chr11_-_77850629 9.64 ENST00000376156.3
ENST00000525870.1
ENST00000530454.1
ENST00000525755.1
ENST00000527099.1
ENST00000525761.1
ENST00000299626.5
ALG8, alpha-1,3-glucosyltransferase
chr19_+_8509842 9.56 ENST00000325495.4
ENST00000600092.1
ENST00000594907.1
ENST00000596984.1
ENST00000601645.1
heterogeneous nuclear ribonucleoprotein M
chr18_+_57567180 9.30 ENST00000316660.6
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr3_+_45017722 9.18 ENST00000265564.7
exosome component 7
chr2_-_179315786 8.92 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr13_-_78492927 8.74 ENST00000334286.5
endothelin receptor type B
chr19_+_42364313 8.52 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
ribosomal protein S19
chr12_-_15114603 8.47 ENST00000228945.4
Rho GDP dissociation inhibitor (GDI) beta
chr7_+_23145884 8.47 ENST00000409689.1
ENST00000410047.1
kelch-like family member 7
chr19_-_19051103 8.47 ENST00000542541.2
ENST00000433218.2
homer homolog 3 (Drosophila)
chr4_+_39699664 8.46 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
ubiquitin-conjugating enzyme E2K
chr6_-_101329191 8.29 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr3_+_184081137 8.24 ENST00000443489.1
polymerase (RNA) II (DNA directed) polypeptide H
chr3_+_69915385 8.05 ENST00000314589.5
microphthalmia-associated transcription factor
chr8_-_74206133 8.00 ENST00000352983.2
ribosomal protein L7
chr8_-_74206673 7.96 ENST00000396465.1
ribosomal protein L7
chr10_+_124913930 7.84 ENST00000368858.5
BUB3 mitotic checkpoint protein
chr22_+_31489344 7.68 ENST00000404574.1
smoothelin
chr7_+_140396946 7.67 ENST00000476470.1
ENST00000471136.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr1_+_155658849 7.47 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
death associated protein 3
chr2_-_130878140 7.24 ENST00000360967.5
ENST00000361163.4
ENST00000357462.5
POTE ankyrin domain family, member F
chr9_-_70488865 7.20 ENST00000377392.5
COBW domain containing 5
chr13_+_48611665 7.19 ENST00000258662.2
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr2_+_11752379 7.14 ENST00000396123.1
growth regulation by estrogen in breast cancer 1
chr2_-_69664549 7.09 ENST00000450796.2
ENST00000484177.1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr11_+_65686728 7.07 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr3_-_49395892 7.00 ENST00000419783.1
glutathione peroxidase 1
chr15_-_89456630 7.00 ENST00000268150.8
milk fat globule-EGF factor 8 protein
chr8_+_126442563 6.97 ENST00000311922.3
tribbles pseudokinase 1
chr3_-_49395705 6.97 ENST00000419349.1
glutathione peroxidase 1
chr6_-_111804905 6.90 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr12_+_119616447 6.82 ENST00000281938.2
heat shock 22kDa protein 8
chr14_+_19553365 6.79 ENST00000409832.3
POTE ankyrin domain family, member G
chr8_-_22926623 6.78 ENST00000276431.4
tumor necrosis factor receptor superfamily, member 10b
chr7_+_140396756 6.73 ENST00000460088.1
ENST00000472695.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr13_+_76334567 6.54 ENST00000321797.8
LIM domain 7
chr7_+_140396465 6.48 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr15_-_89456593 6.35 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
milk fat globule-EGF factor 8 protein
chr17_+_8191815 6.27 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr19_+_535835 6.22 ENST00000607527.1
ENST00000606065.1
cell division cycle 34
chr2_+_131369054 6.15 ENST00000409602.1
POTE ankyrin domain family, member J
chr1_-_153588334 6.07 ENST00000476873.1
S100 calcium binding protein A14
chr7_+_23145347 5.97 ENST00000322231.7
kelch-like family member 7
chrX_+_48334549 5.77 ENST00000019019.2
ENST00000348411.2
ENST00000396894.4
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr9_+_134065506 5.70 ENST00000483497.2
nucleoporin 214kDa
chr6_+_31633833 5.64 ENST00000375882.2
ENST00000375880.2
casein kinase 2, beta polypeptide
Uncharacterized protein
chr4_-_24586140 5.61 ENST00000336812.4
DEAH (Asp-Glu-Ala-His) box helicase 15
chr21_-_35288284 5.48 ENST00000290299.2
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chrX_-_129244655 5.33 ENST00000335997.7
E74-like factor 4 (ets domain transcription factor)
chr2_-_69664586 5.32 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr9_+_119449576 5.13 ENST00000450136.1
ENST00000373983.2
ENST00000411410.1
tripartite motif containing 32
chrX_-_129244454 5.11 ENST00000308167.5
E74-like factor 4 (ets domain transcription factor)
chr8_+_29953163 5.09 ENST00000518192.1
leptin receptor overlapping transcript-like 1
chr11_-_71823266 5.08 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
anaphase promoting complex subunit 15
chr13_-_78492955 5.05 ENST00000446573.1
endothelin receptor type B
chr19_-_17375541 4.98 ENST00000252597.3
Usher syndrome 1C binding protein 1
chr4_+_71554196 4.93 ENST00000254803.2
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr12_-_15114492 4.92 ENST00000541546.1
Rho GDP dissociation inhibitor (GDI) beta
chr10_+_124913793 4.89 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3 mitotic checkpoint protein
chr15_+_42697065 4.80 ENST00000565559.1
calpain 3, (p94)
chr11_+_64073699 4.70 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr2_+_101179152 4.67 ENST00000264254.6
phosducin-like 3
chr12_+_56367697 4.66 ENST00000553116.1
ENST00000360299.5
ENST00000548068.1
ENST00000549915.1
ENST00000551459.1
ENST00000448789.2
RAB5B, member RAS oncogene family
chr14_-_23904861 4.66 ENST00000355349.3
myosin, heavy chain 7, cardiac muscle, beta
chr12_-_125348329 4.59 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
scavenger receptor class B, member 1
chr13_-_50367057 4.56 ENST00000261667.3
karyopherin alpha 3 (importin alpha 4)
chr7_-_142232071 4.51 ENST00000390364.3
T cell receptor beta variable 10-1(gene/pseudogene)
chr1_-_20987982 4.50 ENST00000375048.3
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr1_+_153747746 4.49 ENST00000368661.3
solute carrier family 27 (fatty acid transporter), member 3
chr12_-_125348448 4.42 ENST00000339570.5
scavenger receptor class B, member 1
chr19_-_11688447 4.38 ENST00000590420.1
acid phosphatase 5, tartrate resistant
chr17_-_26662464 4.36 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
intraflagellar transport 20 homolog (Chlamydomonas)
chr1_-_94312706 4.28 ENST00000370244.1
breast cancer anti-estrogen resistance 3
chr7_+_23145366 4.16 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
kelch-like family member 7
chr20_+_34894247 4.14 ENST00000373913.3
discs, large (Drosophila) homolog-associated protein 4
chr4_-_106629796 4.05 ENST00000416543.1
ENST00000515819.1
ENST00000420368.2
ENST00000503746.1
ENST00000340139.5
ENST00000433009.1
integrator complex subunit 12
chr17_-_74707037 4.00 ENST00000355797.3
ENST00000375036.2
ENST00000449428.2
matrix-remodelling associated 7
chr19_-_47288162 3.96 ENST00000594991.1
solute carrier family 1 (neutral amino acid transporter), member 5
chr12_-_52887034 3.92 ENST00000330722.6
keratin 6A
chr12_-_52845910 3.87 ENST00000252252.3
keratin 6B
chr9_+_124088860 3.76 ENST00000373806.1
gelsolin
chr5_-_179499108 3.48 ENST00000521389.1
ring finger protein 130
chr20_+_61867235 3.35 ENST00000342412.6
ENST00000217169.3
baculoviral IAP repeat containing 7
chr10_+_23384435 3.19 ENST00000376510.3
methionine sulfoxide reductase B2
chr3_+_44840679 3.10 ENST00000425755.1
kinesin family member 15
chr10_+_102106829 3.10 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr3_+_14219858 3.09 ENST00000306024.3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_+_93558069 3.08 ENST00000371627.4
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr5_+_179247759 3.07 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
sequestosome 1
chr17_-_12921270 3.06 ENST00000578071.1
ENST00000426905.3
ENST00000395962.2
ENST00000583371.1
ENST00000338034.4
elaC ribonuclease Z 2
chr1_+_86889769 2.89 ENST00000370565.4
chloride channel accessory 2
chr17_-_40729681 2.87 ENST00000590760.1
ENST00000587209.1
ENST00000393795.3
ENST00000253789.5
PSMC3 interacting protein
chr6_+_148663729 2.77 ENST00000367467.3
SAM and SH3 domain containing 1
chr6_-_33385902 2.77 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr2_+_169312725 2.70 ENST00000392687.4
ceramide synthase 6
chr8_+_29952914 2.62 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chr5_+_153570285 2.61 ENST00000425427.2
ENST00000297107.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr1_-_93426998 2.61 ENST00000370310.4
family with sequence similarity 69, member A
chr1_-_32801825 2.60 ENST00000329421.7
MARCKS-like 1
chr3_-_45017609 2.57 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
zinc finger, DHHC-type containing 3
chr1_-_47655686 2.57 ENST00000294338.2
PDZK1 interacting protein 1
chr16_-_70729496 2.57 ENST00000567648.1
Vac14 homolog (S. cerevisiae)
chr11_-_64889529 2.38 ENST00000531743.1
ENST00000527548.1
ENST00000526555.1
ENST00000279259.3
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr9_+_96338647 2.36 ENST00000359246.4
PHD finger protein 2
chr22_+_50628999 2.30 ENST00000395827.1
TraB domain containing
chr22_+_38302285 2.27 ENST00000215957.6
MICAL-like 1
chr17_-_41277467 2.22 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
breast cancer 1, early onset
chr3_+_122044084 2.21 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr5_-_179499086 2.19 ENST00000261947.4
ring finger protein 130
chr11_+_18287721 2.16 ENST00000356524.4
serum amyloid A1
chr10_+_5726764 2.12 ENST00000328090.5
ENST00000496681.1
family with sequence similarity 208, member B
chr19_-_10613421 2.09 ENST00000393623.2
kelch-like ECH-associated protein 1
chr1_+_110198689 2.02 ENST00000369836.4
glutathione S-transferase mu 4
chr11_-_104972158 1.96 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr15_-_31393910 1.96 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
transient receptor potential cation channel, subfamily M, member 1
chr18_+_61143994 1.95 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr22_+_38201114 1.94 ENST00000340857.2
H1 histone family, member 0
chr9_+_116298778 1.93 ENST00000462143.1
regulator of G-protein signaling 3
chr11_-_64889649 1.92 ENST00000434372.2
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr11_-_104905840 1.88 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr2_+_68384976 1.87 ENST00000263657.2
partner of NOB1 homolog (S. cerevisiae)
chr8_+_67341239 1.85 ENST00000320270.2
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr11_-_414948 1.81 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr19_-_51471381 1.75 ENST00000594641.1
kallikrein-related peptidase 6
chr11_+_18287801 1.73 ENST00000532858.1
ENST00000405158.2
serum amyloid A1
chr19_-_11688500 1.73 ENST00000433365.2
acid phosphatase 5, tartrate resistant
chr3_+_133118839 1.72 ENST00000302334.2
beaded filament structural protein 2, phakinin
chr5_-_156486120 1.72 ENST00000522693.1
hepatitis A virus cellular receptor 1
chr6_+_121756809 1.65 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr4_+_671711 1.65 ENST00000400159.2
myosin, light chain 5, regulatory
chr20_-_43280361 1.61 ENST00000372874.4
adenosine deaminase
chr1_-_3447967 1.46 ENST00000294599.4
multiple EGF-like-domains 6
chr15_+_42696992 1.46 ENST00000561817.1
calpain 3, (p94)
chr1_-_109506036 1.41 ENST00000369976.1
ENST00000356970.2
ENST00000369971.2
ENST00000415331.1
ENST00000357393.4
chloride channel CLIC-like 1
AKNA domain containing 1
chr1_-_185286461 1.37 ENST00000367498.3
influenza virus NS1A binding protein
chr16_-_68000717 1.35 ENST00000541864.2
solute carrier family 12 (potassium/chloride transporter), member 4
chr11_+_19138670 1.32 ENST00000446113.2
ENST00000399351.3
zinc finger, DHHC-type containing 13
chr14_-_73925225 1.29 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
numb homolog (Drosophila)
chr17_+_48556158 1.28 ENST00000258955.2
radical S-adenosyl methionine domain containing 1
chr2_-_165698521 1.28 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
cordon-bleu WH2 repeat protein-like 1
chr15_+_42697018 1.27 ENST00000397204.4
calpain 3, (p94)
chr11_-_75017734 1.27 ENST00000532525.1
arrestin, beta 1
chr11_-_64889252 1.23 ENST00000525297.1
ENST00000529259.1
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr11_-_36310958 1.16 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMM domain containing 9

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 23.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
5.4 21.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
4.9 19.7 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
4.6 13.8 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
4.5 18.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
4.5 9.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
4.2 12.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
3.9 23.4 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
3.3 13.4 GO:0071461 cellular response to redox state(GO:0071461)
3.3 10.0 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.8 14.0 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
2.6 13.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
2.6 10.4 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
2.3 7.0 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.3 9.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
2.0 44.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
2.0 11.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.9 30.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
1.9 18.9 GO:0018202 peptidyl-histidine modification(GO:0018202)
1.8 7.2 GO:0006203 dGTP catabolic process(GO:0006203)
1.7 20.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.7 1.7 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.6 16.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.6 17.6 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
1.6 12.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.6 6.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
1.5 11.7 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
1.3 16.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.3 3.9 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.3 3.9 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
1.3 7.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
1.3 7.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.2 2.5 GO:0009217 purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dATP catabolic process(GO:0046061)
1.2 6.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.2 8.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
1.2 10.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.2 4.7 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.2 4.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
1.0 10.4 GO:0001866 NK T cell proliferation(GO:0001866)
1.0 13.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.0 3.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.0 5.1 GO:0030047 actin modification(GO:0030047)
1.0 3.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
1.0 29.5 GO:0031581 hemidesmosome assembly(GO:0031581)
1.0 4.0 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
1.0 3.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.9 43.2 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.9 9.3 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.8 16.1 GO:0032060 bleb assembly(GO:0032060)
0.8 14.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.8 11.3 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.8 2.4 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.8 3.8 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.7 2.2 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.7 5.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.7 2.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.7 8.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.7 34.5 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.6 1.3 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.6 14.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.6 11.8 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.6 9.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.6 7.3 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.6 31.9 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.5 3.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.5 13.8 GO:0010226 response to lithium ion(GO:0010226)
0.5 10.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 17.8 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.4 2.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 10.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.4 4.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.4 3.2 GO:0030091 protein repair(GO:0030091)
0.3 6.1 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.3 1.9 GO:1902570 protein localization to nucleolus(GO:1902570)
0.3 1.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.3 11.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 4.1 GO:0016180 snRNA processing(GO:0016180)
0.2 6.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 0.7 GO:0042369 vitamin D catabolic process(GO:0042369)
0.2 2.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.2 21.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2 5.8 GO:0030488 tRNA methylation(GO:0030488)
0.2 13.8 GO:0001895 retina homeostasis(GO:0001895)
0.2 0.4 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.2 4.6 GO:0019054 modulation by virus of host process(GO:0019054)
0.2 3.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2 1.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.2 1.7 GO:0070307 lens fiber cell development(GO:0070307)
0.2 5.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 4.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 2.6 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.0 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.2 8.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 20.5 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.2 27.2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.1 10.9 GO:0032392 DNA geometric change(GO:0032392)
0.1 10.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 11.5 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.1 1.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 8.5 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 1.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 2.3 GO:0097320 membrane tubulation(GO:0097320)
0.1 1.8 GO:0016540 protein autoprocessing(GO:0016540)
0.1 10.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 3.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 7.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 3.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.5 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.1 0.4 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 2.9 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 2.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 3.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.1 4.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 2.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.0 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.6 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 2.2 GO:0018149 peptide cross-linking(GO:0018149)
0.0 2.8 GO:0010038 response to metal ion(GO:0010038)
0.0 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 4.5 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.9 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 4.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.0 GO:0007398 ectoderm development(GO:0007398)
0.0 1.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.7 GO:0036499 PERK-mediated unfolded protein response(GO:0036499)
0.0 1.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.0 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 2.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.4 GO:0031523 Myb complex(GO:0031523)
5.4 16.1 GO:1902636 kinociliary basal body(GO:1902636)
4.2 12.7 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
4.2 12.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
3.8 34.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
3.0 20.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
2.4 43.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
2.1 30.0 GO:0035631 CD40 receptor complex(GO:0035631)
1.9 5.7 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
1.8 18.1 GO:0097255 R2TP complex(GO:0097255)
1.5 12.1 GO:0005610 laminin-5 complex(GO:0005610)
1.4 11.4 GO:0032133 chromosome passenger complex(GO:0032133)
1.4 20.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.3 6.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
1.3 5.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.2 9.6 GO:0042382 paraspeckles(GO:0042382)
1.1 5.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.0 3.1 GO:0005873 plus-end kinesin complex(GO:0005873)
1.0 2.0 GO:0051286 growing cell tip(GO:0035838) cell tip(GO:0051286)
1.0 11.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 64.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.8 9.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.8 9.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.8 5.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.8 3.8 GO:0097179 protease inhibitor complex(GO:0097179)
0.6 8.9 GO:0070578 RISC-loading complex(GO:0070578)
0.6 6.1 GO:0097413 Lewy body(GO:0097413)
0.6 2.2 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.5 6.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.5 8.5 GO:0032433 filopodium tip(GO:0032433)
0.5 4.1 GO:0032039 integrator complex(GO:0032039)
0.4 3.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 4.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 2.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.3 27.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.3 9.0 GO:0031528 microvillus membrane(GO:0031528)
0.3 7.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 16.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 3.8 GO:0030478 actin cap(GO:0030478)
0.2 3.1 GO:0044754 autolysosome(GO:0044754)
0.2 23.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.7 GO:0005916 fascia adherens(GO:0005916)
0.2 4.7 GO:0032982 myosin filament(GO:0032982)
0.2 22.6 GO:0005882 intermediate filament(GO:0005882)
0.2 10.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 5.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 10.9 GO:0045178 basal part of cell(GO:0045178)
0.2 0.9 GO:1902560 GMP reductase complex(GO:1902560)
0.1 3.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 3.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 8.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.7 GO:0005859 muscle myosin complex(GO:0005859)
0.1 10.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 17.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 9.4 GO:0005604 basement membrane(GO:0005604)
0.1 4.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 12.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 3.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 6.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.3 GO:0031143 pseudopodium(GO:0031143)
0.1 27.5 GO:0005925 focal adhesion(GO:0005925)
0.1 9.7 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 8.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 9.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 22.7 GO:0016607 nuclear speck(GO:0016607)
0.0 2.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 7.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.8 GO:0016605 PML body(GO:0016605)
0.0 1.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 3.1 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 5.1 GO:0072562 blood microparticle(GO:0072562)
0.0 1.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 6.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 5.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.7 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 23.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
4.6 13.8 GO:0004962 endothelin receptor activity(GO:0004962)
3.2 16.1 GO:0002046 opsin binding(GO:0002046)
3.2 9.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
3.0 18.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
3.0 11.8 GO:0004743 pyruvate kinase activity(GO:0004743)
2.7 18.9 GO:0004673 protein histidine kinase activity(GO:0004673)
2.6 44.7 GO:0008494 translation activator activity(GO:0008494)
2.5 12.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
2.4 43.2 GO:0001054 RNA polymerase I activity(GO:0001054)
2.4 7.2 GO:0035529 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
2.3 11.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
2.3 11.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
2.3 9.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.4 14.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.3 13.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.2 5.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
1.1 23.8 GO:0000339 RNA cap binding(GO:0000339)
1.0 8.3 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
1.0 3.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.0 13.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.0 8.9 GO:0070883 pre-miRNA binding(GO:0070883)
0.9 4.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.8 3.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.7 20.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.7 17.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.6 14.5 GO:0055103 ligase regulator activity(GO:0055103)
0.6 1.9 GO:0008097 5S rRNA binding(GO:0008097)
0.6 3.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.6 4.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.6 8.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.6 8.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.6 19.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.5 10.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.5 5.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.5 6.1 GO:0008199 ferric iron binding(GO:0008199)
0.5 14.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 4.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 10.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.4 1.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 5.1 GO:0030957 Tat protein binding(GO:0030957)
0.4 11.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 10.0 GO:0071949 FAD binding(GO:0071949)
0.4 18.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.3 6.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 4.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 3.8 GO:0045159 myosin II binding(GO:0045159)
0.3 2.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 21.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.3 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.3 1.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3 3.8 GO:0050700 CARD domain binding(GO:0050700)
0.3 3.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 15.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.3 9.2 GO:0017091 3'-5'-exoribonuclease activity(GO:0000175) AU-rich element binding(GO:0017091)
0.3 43.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 10.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 5.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 4.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 0.6 GO:0017129 triglyceride binding(GO:0017129)
0.2 2.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 2.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 8.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 10.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 2.0 GO:0043295 glutathione binding(GO:0043295)
0.2 0.9 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 3.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 3.1 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.1 6.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 31.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 6.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.7 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 2.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 6.1 GO:0042379 chemokine receptor binding(GO:0042379)
0.1 3.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 3.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 6.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 8.6 GO:0051087 chaperone binding(GO:0051087)
0.1 3.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.0 GO:0008252 nucleotidase activity(GO:0008252)
0.1 2.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 9.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.8 GO:0005507 copper ion binding(GO:0005507)
0.0 2.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 7.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 5.6 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 3.6 GO:0005178 integrin binding(GO:0005178)
0.0 16.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 4.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.0 GO:0004519 endonuclease activity(GO:0004519)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 18.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.5 12.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 22.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.5 51.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 28.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 60.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.4 18.0 PID MYC PATHWAY C-MYC pathway
0.3 25.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 13.9 PID BARD1 PATHWAY BARD1 signaling events
0.3 13.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 8.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 21.7 PID CDC42 PATHWAY CDC42 signaling events
0.2 7.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 13.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 3.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 12.7 PID P73PATHWAY p73 transcription factor network
0.1 3.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 5.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.9 PID AURORA B PATHWAY Aurora B signaling
0.0 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 4.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 43.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
1.3 14.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.0 9.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.8 59.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.7 37.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.6 14.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.6 12.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 18.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 9.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 18.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.4 26.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.4 10.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 9.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3 13.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 3.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 10.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 7.9 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.3 8.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 6.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 2.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 29.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 5.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 3.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.2 7.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 23.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 3.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 11.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 17.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 11.5 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.2 8.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 5.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 20.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 3.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.1 REACTOME KINESINS Genes involved in Kinesins
0.1 4.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 3.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 8.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 4.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 6.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 6.9 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 3.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 3.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 4.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 7.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions