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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UGGUCCC

Z-value: 1.09

Motif logo

logo of

miRNA associated with seed UGGUCCC

NamemiRBASE accession
hsa-miR-133a-3p.1

Activity profile of UGGUCCC motif

Sorted Z-values of UGGUCCC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_11871371 15.71 ENST00000254977.3
BTBD3
BTB (POZ) domain containing 3
chr4_-_176923483 14.03 ENST00000280187.7
ENST00000512509.1
GPM6A
glycoprotein M6A
chr5_+_140864649 13.94 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr5_+_140749803 13.89 ENST00000576222.1
PCDHGB3
protocadherin gamma subfamily B, 3
chr5_+_140868717 13.78 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr5_+_140797296 13.59 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr5_+_140762268 12.90 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr5_+_140772381 12.80 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr5_+_140739537 12.54 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr6_-_134639180 12.29 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr5_+_140729649 11.89 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr14_+_90863327 10.42 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chrX_+_40440146 9.98 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr5_+_140743859 9.95 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr14_+_23775971 9.64 ENST00000250405.5
BCL2L2
BCL2-like 2
chr5_+_140753444 9.57 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr12_+_79258547 9.30 ENST00000457153.2
SYT1
synaptotagmin I
chr5_-_133561752 9.01 ENST00000519718.1
ENST00000481195.1
CTD-2410N18.5
PPP2CA
S-phase kinase-associated protein 1
protein phosphatase 2, catalytic subunit, alpha isozyme
chr7_+_121513143 8.72 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr10_+_17686124 8.56 ENST00000377524.3
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr5_+_140734570 8.56 ENST00000571252.1
PCDHGA4
protocadherin gamma subfamily A, 4
chr5_+_140810132 8.39 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr22_-_38669030 8.31 ENST00000361906.3
TMEM184B
transmembrane protein 184B
chr6_+_107811162 8.23 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr15_-_37390482 7.80 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr4_-_108641608 7.62 ENST00000265174.4
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr8_-_103876965 7.60 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr17_+_37026106 7.18 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chrX_+_64887512 7.18 ENST00000360270.5
MSN
moesin
chr5_+_140718396 7.15 ENST00000394576.2
PCDHGA2
protocadherin gamma subfamily A, 2
chr9_+_36190853 7.00 ENST00000433436.2
ENST00000538225.1
ENST00000540080.1
CLTA
clathrin, light chain A
chr1_+_47799446 6.94 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr6_-_52441713 6.59 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr6_+_111195973 6.29 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr5_+_140767452 6.06 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr5_+_178286925 5.92 ENST00000322434.3
ZNF354B
zinc finger protein 354B
chr8_-_134309335 5.76 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr12_-_109125285 5.69 ENST00000552871.1
ENST00000261401.3
CORO1C
coronin, actin binding protein, 1C
chr10_-_98346801 5.61 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr6_+_148663729 5.37 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr15_-_49338748 5.32 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chr16_-_15736953 5.13 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
KIAA0430
chr3_+_43328004 5.10 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK
SNF related kinase
chr6_-_128841503 4.99 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr1_-_149889382 4.96 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr22_-_41252962 4.83 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr3_+_11034403 4.79 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr6_-_82462425 4.66 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr9_-_124132483 4.61 ENST00000286713.2
ENST00000538954.1
ENST00000347359.2
STOM
stomatin
chr1_-_43833628 4.55 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr6_-_17706618 4.36 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr1_-_212004090 4.28 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr8_-_30670384 4.20 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr3_+_45730733 4.19 ENST00000418611.1
ENST00000389061.5
SACM1L
SAC1 suppressor of actin mutations 1-like (yeast)
chrX_-_48901012 4.14 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr12_-_76953284 4.10 ENST00000547544.1
ENST00000393249.2
OSBPL8
oxysterol binding protein-like 8
chr6_-_10415470 4.05 ENST00000379604.2
ENST00000379613.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_+_57697216 4.00 ENST00000393043.1
ENST00000269122.3
CLTC
clathrin, heavy chain (Hc)
chr2_-_26205340 3.85 ENST00000264712.3
KIF3C
kinesin family member 3C
chrX_-_153775426 3.85 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr1_-_150947343 3.72 ENST00000271688.6
ENST00000368954.5
CERS2
ceramide synthase 2
chr11_+_64009072 3.68 ENST00000535135.1
ENST00000394540.3
FKBP2
FK506 binding protein 2, 13kDa
chr2_-_174830430 3.67 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr3_-_32544900 3.63 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr5_+_140855495 3.61 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr10_-_126849068 3.57 ENST00000494626.2
ENST00000337195.5
CTBP2
C-terminal binding protein 2
chr5_+_140723601 3.50 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chr16_-_11876408 3.47 ENST00000396516.2
ZC3H7A
zinc finger CCCH-type containing 7A
chr5_+_140792614 3.44 ENST00000398610.2
PCDHGA10
protocadherin gamma subfamily A, 10
chr1_-_155942086 3.40 ENST00000368315.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_201924619 3.38 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr15_+_81071684 3.37 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
KIAA1199
chr19_+_49468558 3.33 ENST00000331825.6
FTL
ferritin, light polypeptide
chr22_-_39239987 3.33 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chr1_-_149900122 3.31 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr17_-_8066250 3.26 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
VAMP2
RP11-599B13.6
vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr19_+_48216600 3.10 ENST00000263277.3
ENST00000538399.1
EHD2
EH-domain containing 2
chr1_-_51984908 3.08 ENST00000371730.2
EPS15
epidermal growth factor receptor pathway substrate 15
chr7_+_129710350 3.00 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr10_-_79686284 2.96 ENST00000372391.2
ENST00000372388.2
DLG5
discs, large homolog 5 (Drosophila)
chr16_-_2390704 2.93 ENST00000301732.5
ENST00000382381.3
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_+_22379120 2.91 ENST00000400259.1
ENST00000344548.3
CDC42
cell division cycle 42
chr4_-_89744457 2.91 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr6_+_39760783 2.88 ENST00000398904.2
ENST00000538976.1
DAAM2
dishevelled associated activator of morphogenesis 2
chr13_-_77900814 2.81 ENST00000544440.2
MYCBP2
MYC binding protein 2, E3 ubiquitin protein ligase
chr14_-_25519095 2.80 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr16_+_5008290 2.79 ENST00000251170.7
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr17_+_38296576 2.78 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr1_+_15736359 2.78 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr2_-_16847084 2.75 ENST00000406434.1
ENST00000381323.3
FAM49A
family with sequence similarity 49, member A
chr19_+_34919257 2.70 ENST00000246548.4
ENST00000590048.2
UBA2
ubiquitin-like modifier activating enzyme 2
chr14_-_23388338 2.68 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23
RNA binding motif protein 23
chr9_-_74383799 2.66 ENST00000377044.4
TMEM2
transmembrane protein 2
chr9_-_123964114 2.63 ENST00000373840.4
RAB14
RAB14, member RAS oncogene family
chr6_-_90121938 2.63 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr17_+_72983674 2.56 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr22_-_28315115 2.54 ENST00000455418.3
ENST00000436663.1
ENST00000320996.10
ENST00000335272.5
PITPNB
phosphatidylinositol transfer protein, beta
chr1_-_159893507 2.52 ENST00000368096.1
TAGLN2
transgelin 2
chrX_-_108976521 2.50 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4
acyl-CoA synthetase long-chain family member 4
chr16_-_10674528 2.47 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr21_-_15755446 2.47 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr1_+_32645269 2.41 ENST00000373610.3
TXLNA
taxilin alpha
chr10_+_85899196 2.29 ENST00000372134.3
GHITM
growth hormone inducible transmembrane protein
chr1_-_40157345 2.26 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr8_-_71519889 2.25 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr17_-_41174424 2.21 ENST00000355653.3
VAT1
vesicle amine transport 1
chr5_+_140782351 2.12 ENST00000573521.1
PCDHGA9
protocadherin gamma subfamily A, 9
chr10_+_6186847 2.10 ENST00000536985.1
ENST00000379789.4
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr19_+_17622415 2.09 ENST00000252603.2
ENST00000600923.1
PGLS
6-phosphogluconolactonase
chr1_+_165796753 1.96 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr17_-_1359443 1.96 ENST00000574295.1
ENST00000398970.5
ENST00000300574.2
CRK
v-crk avian sarcoma virus CT10 oncogene homolog
chr22_-_36784035 1.90 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr14_-_64194745 1.88 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr1_-_154531095 1.85 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr11_-_9025541 1.81 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr5_+_179159813 1.80 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr3_-_48723268 1.77 ENST00000439518.1
ENST00000416649.2
ENST00000341520.4
ENST00000294129.2
NCKIPSD
NCK interacting protein with SH3 domain
chr12_-_133405288 1.77 ENST00000204726.3
GOLGA3
golgin A3
chr14_-_75179774 1.71 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
AREL1
AC007956.1
apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr11_+_57520715 1.70 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr8_-_53626974 1.68 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr3_-_49823941 1.63 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
IP6K1
inositol hexakisphosphate kinase 1
chr10_-_75634260 1.63 ENST00000372765.1
ENST00000351293.3
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr19_-_14629224 1.58 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr5_+_151151471 1.51 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr2_+_27593389 1.51 ENST00000233575.2
ENST00000543024.1
ENST00000537606.1
SNX17
sorting nexin 17
chr19_-_47975417 1.51 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr12_-_51477333 1.50 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
CSRNP2
cysteine-serine-rich nuclear protein 2
chr12_+_10365404 1.39 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_+_33168597 1.35 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr5_-_16509101 1.33 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chrX_+_41192595 1.32 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr19_-_4400415 1.30 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1
SH3-domain GRB2-like 1
chr9_-_21335356 1.30 ENST00000359039.4
KLHL9
kelch-like family member 9
chr11_+_61520075 1.25 ENST00000278836.5
MYRF
myelin regulatory factor
chr7_+_157129660 1.25 ENST00000429029.2
ENST00000262177.4
ENST00000417758.1
ENST00000452797.2
ENST00000443280.1
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr14_+_75348592 1.20 ENST00000334220.4
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr5_+_140710061 1.18 ENST00000517417.1
ENST00000378105.3
PCDHGA1
protocadherin gamma subfamily A, 1
chr1_+_206557366 1.17 ENST00000414007.1
ENST00000419187.2
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr19_+_15218180 1.16 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chrX_-_135962876 1.10 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr6_+_163835669 1.07 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI
QKI, KH domain containing, RNA binding
chr11_-_62414070 1.07 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr20_-_57617831 1.06 ENST00000371033.5
ENST00000355937.4
SLMO2
slowmo homolog 2 (Drosophila)
chr1_-_89458415 1.01 ENST00000321792.5
ENST00000370491.3
RBMXL1
CCBL2
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr17_-_79829190 1.01 ENST00000581876.1
ENST00000584461.1
ENST00000583868.1
ENST00000400721.4
ENST00000269321.7
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr11_-_117186946 0.98 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr2_-_166930131 0.96 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr1_+_110091189 0.95 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr4_-_7873981 0.91 ENST00000360265.4
AFAP1
actin filament associated protein 1
chr19_+_16222439 0.91 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr17_+_7788104 0.86 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr15_-_23034322 0.86 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr20_+_36149602 0.82 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr2_-_238323007 0.81 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr19_+_16187085 0.80 ENST00000300933.4
TPM4
tropomyosin 4
chr16_-_66584059 0.80 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2
thymidine kinase 2, mitochondrial
chr2_-_64881018 0.76 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr17_+_16593539 0.75 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
CCDC144A
coiled-coil domain containing 144A
chr1_-_108507631 0.74 ENST00000527011.1
ENST00000370056.4
VAV3
vav 3 guanine nucleotide exchange factor
chr11_-_6502534 0.70 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr14_+_89029253 0.70 ENST00000251038.5
ENST00000359301.3
ENST00000302216.8
ZC3H14
zinc finger CCCH-type containing 14
chrX_-_124097620 0.68 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr10_-_5855350 0.67 ENST00000456041.1
ENST00000380181.3
ENST00000418688.1
ENST00000380132.4
ENST00000609712.1
ENST00000380191.4
GDI2
GDP dissociation inhibitor 2
chr17_+_5031687 0.65 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr17_+_40834580 0.61 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr6_+_42952237 0.54 ENST00000485511.1
ENST00000394110.3
ENST00000472118.1
ENST00000461010.1
PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr9_+_131549483 0.52 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chr10_-_128077024 0.52 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM12
ADAM metallopeptidase domain 12
chr2_+_109335929 0.50 ENST00000283195.6
RANBP2
RAN binding protein 2
chr17_-_74733404 0.49 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr10_+_104474207 0.48 ENST00000602831.1
ENST00000369893.5
SFXN2
sideroflexin 2
chr1_+_87380299 0.47 ENST00000370551.4
ENST00000370550.5
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr19_+_10828724 0.45 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr3_-_88108192 0.44 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr11_-_71791435 0.43 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
NUMA1
nuclear mitotic apparatus protein 1
chr7_+_91570165 0.41 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
AKAP9
A kinase (PRKA) anchor protein 9
chr17_+_26989109 0.40 ENST00000314616.6
ENST00000347486.4
SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr7_+_30951461 0.38 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr1_+_218458625 0.36 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr12_-_105630016 0.32 ENST00000258530.3
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr9_+_118916082 0.28 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr2_-_232645977 0.28 ENST00000409772.1
PDE6D
phosphodiesterase 6D, cGMP-specific, rod, delta
chr11_-_88796803 0.27 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr19_-_10121144 0.23 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr17_-_5389477 0.21 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
DERL2
derlin 2
chr17_-_40273348 0.20 ENST00000225916.5
KAT2A
K(lysine) acetyltransferase 2A
chr9_+_128024067 0.18 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GAPVD1
GTPase activating protein and VPS9 domains 1
chr16_+_12995468 0.17 ENST00000424107.3
ENST00000558583.1
ENST00000558318.1
SHISA9
shisa family member 9
chr15_+_91411810 0.16 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr8_-_38326139 0.14 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
FGFR1
fibroblast growth factor receptor 1
chr11_-_118047376 0.13 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr1_+_33116743 0.13 ENST00000414241.3
ENST00000373493.5
RBBP4
retinoblastoma binding protein 4
chr3_-_15901278 0.12 ENST00000399451.2
ANKRD28
ankyrin repeat domain 28
chr20_+_36322408 0.07 ENST00000361383.6
ENST00000447935.1
ENST00000405275.2
CTNNBL1
catenin, beta like 1
chr2_+_5832799 0.06 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr2_+_33661382 0.06 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr17_+_4736627 0.04 ENST00000355280.6
ENST00000347992.7
MINK1
misshapen-like kinase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of UGGUCCC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
2.1 6.3 GO:0006597 spermine biosynthetic process(GO:0006597)
2.0 5.9 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
1.9 7.6 GO:0000103 sulfate assimilation(GO:0000103)
1.8 12.3 GO:0070294 renal sodium ion absorption(GO:0070294)
1.4 9.6 GO:0060011 Sertoli cell proliferation(GO:0060011)
1.3 5.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.2 10.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.2 8.6 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
1.2 4.8 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.2 7.2 GO:0022614 membrane to membrane docking(GO:0022614)
1.2 6.9 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
1.1 7.7 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
1.1 7.6 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
1.0 6.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.0 4.0 GO:0003409 optic cup structural organization(GO:0003409)
1.0 5.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
1.0 161.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.9 6.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.8 3.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.8 4.8 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.8 3.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.8 4.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.7 3.7 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.7 2.9 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.6 1.9 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.6 9.0 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.6 1.8 GO:0060926 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.6 11.2 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.6 4.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.6 5.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.5 5.8 GO:0090232 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.5 2.5 GO:0070836 caveola assembly(GO:0070836)
0.5 2.0 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.5 5.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.5 3.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 1.9 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.5 3.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.5 4.6 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.4 3.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 2.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.4 2.6 GO:0071233 cellular response to leucine(GO:0071233)
0.4 3.0 GO:0071896 negative regulation of hippo signaling(GO:0035331) protein localization to adherens junction(GO:0071896)
0.4 1.7 GO:0030242 pexophagy(GO:0030242)
0.4 1.2 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.4 3.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 4.8 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.4 2.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 5.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 1.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 12.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 2.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 1.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 2.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.3 4.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2 2.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.8 GO:0070459 prolactin secretion(GO:0070459)
0.2 0.5 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.2 3.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 2.0 GO:0001878 response to yeast(GO:0001878)
0.2 0.8 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 0.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) positive regulation of hexokinase activity(GO:1903301)
0.2 1.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 1.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 4.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.4 GO:0072229 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229) metanephric proximal tubule development(GO:0072237)
0.1 7.3 GO:0090102 cochlea development(GO:0090102)
0.1 1.2 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1 2.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 12.6 GO:0021987 cerebral cortex development(GO:0021987)
0.1 3.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 2.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 5.5 GO:0008542 visual learning(GO:0008542)
0.1 0.3 GO:1902938 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 1.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 1.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 3.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.9 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.1 0.8 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 4.2 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.2 GO:0043983 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) histone H4-K12 acetylation(GO:0043983)
0.1 1.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 1.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.9 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 0.1 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.7 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 2.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 4.7 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.5 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 1.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 2.4 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 1.5 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.9 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.5 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 1.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 2.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.8 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 4.1 GO:0006959 humoral immune response(GO:0006959)
0.0 1.8 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0072534 perineuronal net(GO:0072534)
2.9 8.6 GO:0033565 ESCRT-0 complex(GO:0033565)
1.9 9.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.2 11.0 GO:0071439 clathrin complex(GO:0071439)
0.8 3.3 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.8 3.3 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.7 2.7 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.7 8.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.6 14.0 GO:0044295 axonal growth cone(GO:0044295)
0.6 1.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.6 1.8 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.4 2.6 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 7.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 5.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 4.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.4 13.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 4.8 GO:0016600 flotillin complex(GO:0016600)
0.4 2.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.4 2.9 GO:0000322 storage vacuole(GO:0000322)
0.4 1.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 3.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 3.6 GO:0097470 ribbon synapse(GO:0097470)
0.2 1.4 GO:0032590 dendrite membrane(GO:0032590)
0.2 2.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 1.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 10.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.7 GO:0005915 zonula adherens(GO:0005915)
0.2 16.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 3.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0055028 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.1 0.4 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 2.8 GO:0000145 exocyst(GO:0000145)
0.1 3.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 3.6 GO:0035579 specific granule membrane(GO:0035579)
0.1 8.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 3.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 5.5 GO:0002102 podosome(GO:0002102)
0.1 0.5 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0042588 zymogen granule(GO:0042588)
0.1 3.8 GO:0005871 kinesin complex(GO:0005871)
0.1 142.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 6.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 10.4 GO:0000922 spindle pole(GO:0000922)
0.1 2.5 GO:0005901 caveola(GO:0005901)
0.1 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 10.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 4.9 GO:0045121 membrane raft(GO:0045121)
0.0 2.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0030496 midbody(GO:0030496)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 18.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.5 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0032184 SUMO polymer binding(GO:0032184)
2.5 7.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
2.1 2.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
1.9 9.3 GO:0030348 syntaxin-3 binding(GO:0030348)
1.3 3.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.3 8.9 GO:0004849 uridine kinase activity(GO:0004849)
1.1 7.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.0 4.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.0 2.9 GO:0032427 GBD domain binding(GO:0032427)
0.9 5.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.8 4.8 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.8 4.8 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.8 4.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6 3.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.6 7.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.5 4.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.5 3.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.5 13.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.5 10.4 GO:0050811 GABA receptor binding(GO:0050811)
0.5 12.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.4 4.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 8.5 GO:0051400 BH domain binding(GO:0051400)
0.4 2.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 3.4 GO:0015266 protein channel activity(GO:0015266) P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 2.7 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.3 1.0 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 6.3 GO:0043495 protein anchor(GO:0043495)
0.3 1.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 5.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 1.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 0.8 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.3 3.3 GO:0008199 ferric iron binding(GO:0008199)
0.2 2.7 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 1.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 1.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.2 178.7 GO:0005509 calcium ion binding(GO:0005509)
0.2 4.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 5.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 2.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 4.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 18.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 2.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 3.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.5 GO:0031489 myosin V binding(GO:0031489)
0.1 1.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 1.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 6.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 10.7 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 3.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 2.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 6.3 GO:0070405 ammonium ion binding(GO:0070405)
0.1 4.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 7.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 2.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 4.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 4.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 3.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 2.1 GO:0019003 GDP binding(GO:0019003)
0.0 3.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 2.9 GO:0005319 lipid transporter activity(GO:0005319)
0.0 6.0 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 3.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 2.1 GO:0019902 phosphatase binding(GO:0019902)
0.0 3.4 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 7.7 PID ARF 3PATHWAY Arf1 pathway
0.2 3.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 9.2 PID MYC PATHWAY C-MYC pathway
0.2 8.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 7.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 12.6 PID INSULIN PATHWAY Insulin Pathway
0.2 1.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 4.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 9.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 6.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 3.4 PID REELIN PATHWAY Reelin signaling pathway
0.1 5.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 5.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.6 PID IFNG PATHWAY IFN-gamma pathway
0.1 5.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 4.1 PID E2F PATHWAY E2F transcription factor network
0.0 3.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 4.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 3.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.3 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.6 11.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.5 10.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.4 14.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 12.0 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.3 7.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 4.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 7.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 7.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 6.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 4.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 3.8 REACTOME KINESINS Genes involved in Kinesins
0.2 3.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 4.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 2.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 7.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 2.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 3.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 2.5 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 6.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.9 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.2 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates