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averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for UUGGCAC

Z-value: 1.62

Motif logo

miRNA associated with seed UUGGCAC

NamemiRBASE accession
MIMAT0000095
MIMAT0005796

Activity profile of UUGGCAC motif

Sorted Z-values of UUGGCAC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_20812690 41.70 ENST00000375078.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chrX_-_13956737 40.53 ENST00000454189.2
glycoprotein M6B
chr4_-_176923483 37.50 ENST00000280187.7
ENST00000512509.1
glycoprotein M6A
chr8_+_80523321 31.65 ENST00000518111.1
stathmin-like 2
chr16_+_8768422 30.71 ENST00000268251.8
ENST00000564714.1
4-aminobutyrate aminotransferase
chr2_+_203499901 24.28 ENST00000303116.6
ENST00000392238.2
family with sequence similarity 117, member B
chr3_+_115342159 24.13 ENST00000305124.6
growth associated protein 43
chr1_+_151043070 24.04 ENST00000368918.3
ENST00000368917.1
GA binding protein transcription factor, beta subunit 2
chr14_-_74551172 21.33 ENST00000553458.1
aldehyde dehydrogenase 6 family, member A1
chr2_+_113033164 20.73 ENST00000409871.1
ENST00000343936.4
zinc finger CCCH-type containing 6
chr5_+_71403061 20.61 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr7_+_98246588 20.58 ENST00000265634.3
neuronal pentraxin II
chr15_-_83316254 19.93 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr5_+_173472607 19.62 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr10_+_105036909 19.58 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr8_-_134309335 19.51 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
N-myc downstream regulated 1
chr12_+_113229737 19.46 ENST00000551052.1
ENST00000415485.3
rabphilin 3A homolog (mouse)
chr17_-_78450398 18.81 ENST00000306773.4
neuronal pentraxin I
chr17_+_47865917 18.66 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
K(lysine) acetyltransferase 7
chr6_-_6007200 18.44 ENST00000244766.2
neuritin 1
chr17_-_79139817 18.40 ENST00000326724.4
apoptosis-associated tyrosine kinase
chr22_+_40390930 18.37 ENST00000333407.6
family with sequence similarity 83, member F
chr4_+_128554081 18.00 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chrX_+_110339439 17.98 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
p21 protein (Cdc42/Rac)-activated kinase 3
chr9_-_139094988 17.73 ENST00000371746.3
LIM homeobox 3
chr5_+_17217669 17.69 ENST00000322611.3
brain abundant, membrane attached signal protein 1
chr19_+_18208603 17.43 ENST00000262811.6
microtubule associated serine/threonine kinase 3
chr18_-_5544241 17.26 ENST00000341928.2
ENST00000540638.2
erythrocyte membrane protein band 4.1-like 3
chr9_-_104249319 17.18 ENST00000374847.1
transmembrane protein 246
chr10_-_15413035 17.03 ENST00000378116.4
ENST00000455654.1
family with sequence similarity 171, member A1
chr12_-_42538657 16.98 ENST00000398675.3
glucoside xylosyltransferase 1
chr11_-_45687128 16.86 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr3_-_133614597 15.88 ENST00000285208.4
ENST00000460865.3
RAB6B, member RAS oncogene family
chr5_-_115910630 15.49 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_-_56502375 15.36 ENST00000288221.6
ELKS/RAB6-interacting/CAST family member 2
chr8_+_42752053 15.21 ENST00000307602.4
hook microtubule-tethering protein 3
chr9_-_139922631 15.14 ENST00000341511.6
ATP-binding cassette, sub-family A (ABC1), member 2
chr10_+_104613980 15.14 ENST00000339834.5
chromosome 10 open reading frame 32
chr2_-_220110187 14.88 ENST00000295759.7
ENST00000392089.2
galactosidase, beta 1-like
chr4_+_47033345 14.85 ENST00000295454.3
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr17_+_57232690 14.78 ENST00000262293.4
proline rich 11
chr7_-_111846435 14.64 ENST00000437633.1
ENST00000428084.1
dedicator of cytokinesis 4
chr1_-_41131326 14.61 ENST00000372684.3
regulating synaptic membrane exocytosis 3
chr2_-_44588893 14.47 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
prolyl endopeptidase-like
chr10_+_92980517 14.38 ENST00000336126.5
polycomb group ring finger 5
chr5_+_152870106 14.31 ENST00000285900.5
glutamate receptor, ionotropic, AMPA 1
chr20_-_50384864 14.27 ENST00000311637.5
ENST00000402822.1
ATPase, class II, type 9A
chr8_+_58907104 14.19 ENST00000361488.3
family with sequence similarity 110, member B
chr16_+_12070567 14.08 ENST00000566228.1
sorting nexin 29
chr11_-_73309228 14.06 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A
chr12_-_124457371 13.95 ENST00000238156.3
ENST00000545037.1
coiled-coil domain containing 92
chr3_-_170303845 13.93 ENST00000231706.5
solute carrier family 7, member 14
chr12_-_57914275 13.85 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DNA-damage-inducible transcript 3
chr22_+_31031639 13.80 ENST00000343605.4
ENST00000300385.8
solute carrier family 35, member E4
chr3_+_138066539 13.63 ENST00000289104.4
muscle RAS oncogene homolog
chr8_+_120885949 13.50 ENST00000523492.1
ENST00000286234.5
DEP domain containing MTOR-interacting protein
chr13_+_58206655 12.99 ENST00000377918.3
protocadherin 17
chr22_-_36903101 12.87 ENST00000397224.4
FAD-dependent oxidoreductase domain containing 2
chr1_-_115212696 12.73 ENST00000393276.3
ENST00000393277.1
DENN/MADD domain containing 2C
chrX_+_44732757 12.66 ENST00000377967.4
ENST00000536777.1
ENST00000382899.4
ENST00000543216.1
lysine (K)-specific demethylase 6A
chr1_+_50574585 12.44 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr15_+_51200859 12.22 ENST00000261842.5
adaptor-related protein complex 4, epsilon 1 subunit
chr2_+_173600671 12.02 ENST00000409036.1
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_78245303 11.89 ENST00000370791.3
ENST00000443751.2
family with sequence similarity 73, member A
chr17_-_1532106 11.84 ENST00000301335.5
ENST00000382147.4
solute carrier family 43 (amino acid system L transporter), member 2
chr7_+_87257701 11.56 ENST00000338056.3
ENST00000493037.1
RUN domain containing 3B
chr17_-_34890759 11.42 ENST00000431794.3
myosin XIX
chr1_-_15911510 11.40 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chrX_-_40594755 11.38 ENST00000324817.1
mediator complex subunit 14
chr4_-_16900217 11.29 ENST00000441778.2
LIM domain binding 2
chr2_+_32502952 11.27 ENST00000238831.4
Yip1 domain family, member 4
chr2_+_46524537 11.21 ENST00000263734.3
endothelial PAS domain protein 1
chr11_-_115375107 11.04 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr16_-_19896220 11.03 ENST00000562469.1
ENST00000300571.2
G protein-coupled receptor, family C, group 5, member B
chr14_+_74111578 10.97 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
dynein, axonemal, light chain 1
chr21_-_32931290 10.93 ENST00000286827.3
T-cell lymphoma invasion and metastasis 1
chrX_+_70316005 10.93 ENST00000374259.3
forkhead box O4
chr3_-_57678772 10.90 ENST00000311128.5
DENN/MADD domain containing 6A
chr5_+_76506706 10.79 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
phosphodiesterase 8B
chr7_+_87563458 10.76 ENST00000398204.4
ADAM metallopeptidase domain 22
chr20_+_44657845 10.75 ENST00000243964.3
solute carrier family 12 (potassium/chloride transporter), member 5
chr5_+_75378997 10.61 ENST00000502798.2
synaptic vesicle glycoprotein 2C
chr2_+_219824357 10.60 ENST00000302625.4
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr7_-_158380465 10.52 ENST00000389413.3
ENST00000409483.1
protein tyrosine phosphatase, receptor type, N polypeptide 2
chrX_+_122993827 10.47 ENST00000371199.3
X-linked inhibitor of apoptosis
chr10_+_104629199 10.39 ENST00000369880.3
arsenic (+3 oxidation state) methyltransferase
chr2_-_201936302 10.29 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr6_-_34360413 10.28 ENST00000607016.1
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr9_+_4490394 10.25 ENST00000262352.3
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr17_+_17942594 10.23 ENST00000268719.4
GID complex subunit 4
chr13_+_24734844 10.00 ENST00000382108.3
spermatogenesis associated 13
chr9_+_130159504 9.73 ENST00000373352.1
ENST00000373360.3
solute carrier family 2 (facilitated glucose transporter), member 8
chr1_-_109584608 9.52 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WD repeat domain 47
chr6_+_69345166 9.48 ENST00000370598.1
brain-specific angiogenesis inhibitor 3
chr11_-_64570706 9.45 ENST00000294066.2
ENST00000377350.3
mitogen-activated protein kinase kinase kinase kinase 2
chr9_-_23821273 9.44 ENST00000380110.4
ELAV like neuron-specific RNA binding protein 2
chr11_-_31839488 9.33 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
paired box 6
chr6_+_17600576 9.28 ENST00000259963.3
family with sequence similarity 8, member A1
chr4_+_86396265 9.21 ENST00000395184.1
Rho GTPase activating protein 24
chrX_+_23352133 9.07 ENST00000379361.4
patched domain containing 1
chr19_-_18632861 9.07 ENST00000262809.4
elongation factor RNA polymerase II
chr2_-_183903133 9.02 ENST00000361354.4
NCK-associated protein 1
chr2_-_152955537 8.99 ENST00000201943.5
ENST00000539935.1
calcium channel, voltage-dependent, beta 4 subunit
chr3_-_66551351 8.92 ENST00000273261.3
leucine-rich repeats and immunoglobulin-like domains 1
chr1_-_86043921 8.89 ENST00000535924.2
dimethylarginine dimethylaminohydrolase 1
chr2_-_101034070 8.88 ENST00000264249.3
carbohydrate sulfotransferase 10
chr17_+_73043301 8.87 ENST00000322444.6
potassium channel tetramerization domain containing 2
chr6_-_169654139 8.76 ENST00000366787.3
thrombospondin 2
chr14_+_105781048 8.59 ENST00000458164.2
ENST00000447393.1
phosphofurin acidic cluster sorting protein 2
chr4_-_90229142 8.55 ENST00000609438.1
GPRIN family member 3
chr6_+_138483058 8.37 ENST00000251691.4
KIAA1244
chr12_+_6961279 8.33 ENST00000229268.8
ENST00000389231.5
ENST00000542087.1
ubiquitin specific peptidase 5 (isopeptidase T)
chr1_-_16678914 8.27 ENST00000375592.3
F-box protein 42
chr2_-_218808771 8.23 ENST00000449814.1
ENST00000171887.4
tensin 1
chr15_+_75118888 8.19 ENST00000395018.4
complexin 3
chr2_+_166095898 8.07 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr4_-_88141755 7.98 ENST00000273963.5
kelch-like family member 8
chr4_+_78078304 7.94 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
cyclin G2
chr2_+_231902193 7.77 ENST00000373640.4
chromosome 2 open reading frame 72
chr16_+_50775948 7.77 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
cylindromatosis (turban tumor syndrome)
chr3_-_114790179 7.74 ENST00000462705.1
zinc finger and BTB domain containing 20
chr8_+_1449532 7.72 ENST00000421627.2
discs, large (Drosophila) homolog-associated protein 2
chr12_-_104234966 7.71 ENST00000392876.3
5'-nucleotidase domain containing 3
chr1_+_109792641 7.68 ENST00000271332.3
cadherin, EGF LAG seven-pass G-type receptor 2
chr10_-_11653753 7.55 ENST00000609104.1
USP6 N-terminal like
chr18_-_53255766 7.54 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr13_+_98794810 7.50 ENST00000595437.1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_+_118846008 7.50 ENST00000245787.4
insulin induced gene 2
chr14_-_103523745 7.47 ENST00000361246.2
CDC42 binding protein kinase beta (DMPK-like)
chr19_+_1752372 7.42 ENST00000382349.4
one cut homeobox 3
chr14_+_75536280 7.37 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr12_+_69864129 7.33 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
fibroblast growth factor receptor substrate 2
chr9_+_104161123 7.32 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
zinc finger protein 189
chr3_+_39851094 7.32 ENST00000302541.6
myosin VIIA and Rab interacting protein
chrX_-_107979616 7.25 ENST00000372129.2
insulin receptor substrate 4
chr10_+_95517566 7.24 ENST00000542308.1
leucine-rich, glioma inactivated 1
chr11_+_70244510 7.20 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
cortactin
chr3_+_4535025 7.13 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
inositol 1,4,5-trisphosphate receptor, type 1
chr19_-_10341948 7.13 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr10_+_104678032 7.00 ENST00000369878.4
ENST00000369875.3
cyclin M2
chr2_+_207308220 7.00 ENST00000264377.3
ADAM metallopeptidase domain 23
chr12_-_120554534 7.00 ENST00000538903.1
ENST00000534951.1
RAB35, member RAS oncogene family
chr10_+_120789223 6.98 ENST00000425699.1
nanos homolog 1 (Drosophila)
chr1_-_109940550 6.92 ENST00000256637.6
sortilin 1
chr17_+_77751931 6.91 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr2_-_86564776 6.90 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
receptor accessory protein 1
chr5_-_171433819 6.90 ENST00000296933.6
F-box and WD repeat domain containing 11
chr11_+_92085262 6.89 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr2_-_73340146 6.80 ENST00000258098.6
RAB11 family interacting protein 5 (class I)
chr22_+_30792846 6.66 ENST00000312932.9
ENST00000428195.1
SEC14-like 2 (S. cerevisiae)
chr2_+_173940442 6.65 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
Mitogen-activated protein kinase kinase kinase MLT
chrX_+_136648297 6.63 ENST00000287538.5
Zic family member 3
chr15_+_31619013 6.59 ENST00000307145.3
Kruppel-like factor 13
chr3_-_50540854 6.58 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr9_-_140115775 6.57 ENST00000391553.1
ENST00000392827.1
ring finger protein 208
chr6_-_34664612 6.54 ENST00000374023.3
ENST00000374026.3
chromosome 6 open reading frame 106
chr1_+_205473720 6.45 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr8_+_37654424 6.39 ENST00000315215.7
G protein-coupled receptor 124
chr6_-_39197226 6.37 ENST00000359534.3
potassium channel, subfamily K, member 5
chr19_-_14316980 6.30 ENST00000361434.3
ENST00000340736.6
latrophilin 1
chr14_+_105331596 6.22 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
centrosomal protein 170B
chr17_-_74722672 6.19 ENST00000397625.4
ENST00000445478.2
jumonji domain containing 6
chr8_-_22550815 6.13 ENST00000317216.2
early growth response 3
chr2_+_241375069 6.13 ENST00000264039.2
glypican 1
chr2_-_30144432 6.11 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr5_-_114598548 6.09 ENST00000379615.3
ENST00000419445.1
protein geranylgeranyltransferase type I, beta subunit
chr15_-_72410109 6.04 ENST00000564571.1
myosin IXA
chr3_-_15374033 6.02 ENST00000253688.5
ENST00000383791.3
SH3-domain binding protein 5 (BTK-associated)
chr14_-_51562745 5.92 ENST00000298355.3
tripartite motif containing 9
chr2_-_213403565 5.85 ENST00000342788.4
ENST00000436443.1
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr7_-_51384451 5.84 ENST00000441453.1
ENST00000265136.7
ENST00000395542.2
ENST00000395540.2
cordon-bleu WH2 repeat protein
chrX_+_37208521 5.79 ENST00000378628.4
proline rich Gla (G-carboxyglutamic acid) 1
chr21_-_42219065 5.76 ENST00000400454.1
Down syndrome cell adhesion molecule
chr13_-_41240717 5.67 ENST00000379561.5
forkhead box O1
chr1_-_201915590 5.66 ENST00000367288.4
leiomodin 1 (smooth muscle)
chr19_+_3094398 5.62 ENST00000078429.4
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr1_-_202858227 5.61 ENST00000367262.3
RAB interacting factor
chr12_-_54673871 5.58 ENST00000209875.4
chromobox homolog 5
chr13_-_53422640 5.56 ENST00000338862.4
ENST00000377942.3
protocadherin 8
chr1_+_200708671 5.37 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr9_-_125675576 5.37 ENST00000373659.3
zinc finger and BTB domain containing 6
chr7_+_66093851 5.35 ENST00000275532.3
potassium channel tetramerization domain containing 7
chr5_-_95297678 5.33 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chrX_-_133119895 5.31 ENST00000370818.3
glypican 3
chr2_-_167232484 5.30 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
sodium channel, voltage-gated, type IX, alpha subunit
chr15_-_34628951 5.29 ENST00000397707.2
ENST00000560611.1
solute carrier family 12 (potassium/chloride transporter), member 6
chr2_-_166060571 5.28 ENST00000360093.3
sodium channel, voltage-gated, type III, alpha subunit
chr12_+_57943781 5.26 ENST00000455537.2
ENST00000286452.5
kinesin family member 5A
chr16_-_29910365 5.25 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr10_-_70287231 5.19 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr13_-_20735178 5.18 ENST00000241125.3
gap junction protein, alpha 3, 46kDa
chr1_-_177133818 5.18 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr12_+_55413721 5.15 ENST00000242994.3
neuronal differentiation 4
chr1_+_113615794 5.15 ENST00000361127.5
leucine-rich repeats and immunoglobulin-like domains 2
chr11_+_111473108 5.15 ENST00000304987.3
salt-inducible kinase 2
chr12_-_93323013 5.10 ENST00000322349.8
early endosome antigen 1
chr5_+_118407053 5.02 ENST00000311085.8
ENST00000539542.1
Dmx-like 1
chr2_-_166930131 4.88 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
sodium channel, voltage-gated, type I, alpha subunit
chr17_+_36508111 4.88 ENST00000331159.5
ENST00000577233.1
suppressor of cytokine signaling 7
chr9_-_115480303 4.88 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INTS3 and NABP interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of UUGGCAC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 31.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
7.7 30.7 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
5.3 21.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
4.7 18.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
4.2 12.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
4.1 40.5 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
3.8 15.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
3.7 3.7 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
3.5 17.7 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
3.5 10.6 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
3.5 10.5 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
3.0 8.9 GO:0032474 otolith morphogenesis(GO:0032474)
3.0 17.7 GO:0021523 somatic motor neuron differentiation(GO:0021523)
2.9 14.6 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
2.9 5.8 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
2.8 11.4 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
2.8 13.8 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
2.8 11.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
2.7 10.9 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
2.7 10.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
2.6 7.8 GO:1990108 protein linear deubiquitination(GO:1990108)
2.5 17.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
2.4 7.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
2.4 24.1 GO:0016198 axon choice point recognition(GO:0016198)
2.4 12.0 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
2.3 9.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
2.2 2.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
2.2 18.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
2.2 11.2 GO:0043129 surfactant homeostasis(GO:0043129)
2.2 6.7 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
2.2 6.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
2.1 4.2 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
2.1 10.3 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
2.0 6.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
2.0 19.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
2.0 19.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
1.9 18.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
1.9 9.3 GO:0003322 pancreatic A cell development(GO:0003322)
1.9 13.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
1.8 10.9 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
1.8 14.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.8 7.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
1.8 5.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
1.7 3.4 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.7 21.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
1.5 6.1 GO:0036269 swimming behavior(GO:0036269)
1.5 4.6 GO:0097476 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
1.5 4.5 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.5 5.8 GO:0001757 somite specification(GO:0001757)
1.4 4.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.4 1.4 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
1.4 10.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
1.4 7.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.4 5.7 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
1.4 15.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.4 15.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.4 4.1 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
1.3 5.3 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
1.3 5.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.3 10.2 GO:0070777 sulfur amino acid transport(GO:0000101) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.2 6.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.2 11.0 GO:0036158 outer dynein arm assembly(GO:0036158)
1.2 14.6 GO:0045792 negative regulation of cell size(GO:0045792)
1.2 4.8 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
1.2 8.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.1 18.0 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
1.1 3.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.1 6.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) determination of digestive tract left/right asymmetry(GO:0071907)
1.1 4.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
1.1 7.7 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
1.1 2.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.1 3.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.0 2.1 GO:0002537 nitric oxide production involved in inflammatory response(GO:0002537)
1.0 3.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
1.0 4.0 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
1.0 9.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.0 3.0 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
1.0 5.9 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
1.0 6.8 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
1.0 2.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.9 5.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.9 33.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.9 3.6 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.9 7.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.9 8.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.9 9.8 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.9 5.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.9 3.4 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.8 2.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.8 16.9 GO:0006012 galactose metabolic process(GO:0006012)
0.8 34.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 5.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.8 1.6 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.8 2.4 GO:0001554 luteolysis(GO:0001554)
0.8 3.9 GO:0003431 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384)
0.8 2.3 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.8 6.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.8 14.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.7 14.9 GO:0071420 cellular response to histamine(GO:0071420)
0.7 2.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.7 11.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.7 17.6 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.7 4.4 GO:0016577 histone demethylation(GO:0016577)
0.7 2.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155) fasciculation of motor neuron axon(GO:0097156)
0.7 8.9 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.7 14.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.7 4.0 GO:0021764 amygdala development(GO:0021764)
0.7 7.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.6 19.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 8.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.6 7.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.6 4.2 GO:0001842 neural fold formation(GO:0001842)
0.6 1.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.6 13.8 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.6 10.8 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.6 3.6 GO:0060017 parathyroid gland development(GO:0060017)
0.6 6.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.6 1.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.6 1.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.6 8.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.5 4.9 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.5 8.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.5 6.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.5 11.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.5 5.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 2.6 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.5 4.1 GO:0002118 aggressive behavior(GO:0002118)
0.5 15.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.5 11.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 12.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.5 6.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.5 2.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.5 2.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.5 9.7 GO:0007141 male meiosis I(GO:0007141)
0.5 5.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.5 4.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 0.9 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.4 1.3 GO:0035627 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.4 4.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 4.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 3.9 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.4 10.4 GO:0009404 toxin metabolic process(GO:0009404)
0.4 4.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 13.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.4 3.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.4 12.9 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.4 1.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 8.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.4 2.5 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.4 2.8 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.4 0.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 4.9 GO:0021794 thalamus development(GO:0021794)
0.4 2.8 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 4.2 GO:0014850 response to muscle activity(GO:0014850)
0.3 3.5 GO:1901621 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 1.4 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.3 1.0 GO:0006021 inositol biosynthetic process(GO:0006021)
0.3 5.3 GO:0048266 behavioral response to pain(GO:0048266)
0.3 1.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 2.9 GO:0010761 fibroblast migration(GO:0010761)
0.3 1.0 GO:1902803 regulation of synaptic vesicle transport(GO:1902803)
0.3 2.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 6.9 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.3 2.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.3 2.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.3 8.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.3 2.5 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.3 3.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.3 11.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 4.2 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.3 2.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 1.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.3 1.8 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 14.1 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.2 16.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 3.1 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 13.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 0.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.2 2.0 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.2 3.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 10.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.2 6.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 0.2 GO:0003064 regulation of heart rate by hormone(GO:0003064)
0.2 5.1 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 1.4 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.2 2.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 3.1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.2 6.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 4.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 20.2 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2 0.9 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 7.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 5.2 GO:0032456 endocytic recycling(GO:0032456)
0.2 8.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 3.3 GO:0034389 lipid particle organization(GO:0034389)
0.2 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 16.4 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 20.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 3.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.4 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 1.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 1.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 11.0 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 4.8 GO:1901998 toxin transport(GO:1901998)
0.1 6.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 7.5 GO:0008306 associative learning(GO:0008306)
0.1 1.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:2000282 regulation of arginine metabolic process(GO:0000821) regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of adrenergic receptor signaling pathway(GO:0071878) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.6 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.9 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.1 3.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.9 GO:0021549 cerebellum development(GO:0021549)
0.1 1.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 3.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 2.9 GO:0010107 potassium ion import(GO:0010107)
0.1 0.5 GO:0019532 oxalate transport(GO:0019532)
0.1 1.6 GO:0003416 endochondral bone growth(GO:0003416)
0.1 1.6 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 2.3 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.1 0.1 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 9.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 21.5 GO:0051260 protein homooligomerization(GO:0051260)
0.1 1.1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 3.0 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.1 3.3 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 1.3 GO:0097503 sialylation(GO:0097503)
0.1 3.3 GO:0051262 protein tetramerization(GO:0051262)
0.1 1.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 11.2 GO:0007601 visual perception(GO:0007601)
0.1 4.5 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 2.0 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 4.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 2.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.6 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 2.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 1.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.7 GO:0021987 cerebral cortex development(GO:0021987)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 30.7 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
4.6 13.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
3.9 19.4 GO:0044308 axonal spine(GO:0044308)
3.8 15.2 GO:0070695 FHF complex(GO:0070695)
3.4 24.1 GO:0032584 growth cone membrane(GO:0032584)
2.6 10.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.5 50.1 GO:0044295 axonal growth cone(GO:0044295)
2.3 11.4 GO:0070847 core mediator complex(GO:0070847)
2.0 6.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.9 7.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.7 5.0 GO:0043291 RAVE complex(GO:0043291)
1.5 25.3 GO:0033270 paranode region of axon(GO:0033270)
1.5 22.0 GO:0005883 neurofilament(GO:0005883)
1.4 11.0 GO:0036157 outer dynein arm(GO:0036157)
1.4 4.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.3 15.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.2 4.9 GO:0070876 SOSS complex(GO:0070876)
1.2 12.7 GO:0044666 MLL3/4 complex(GO:0044666)
1.1 15.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.1 5.3 GO:0035253 ciliary rootlet(GO:0035253)
0.9 3.8 GO:1990745 EARP complex(GO:1990745)
0.9 18.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.9 4.6 GO:0045298 tubulin complex(GO:0045298)
0.8 7.6 GO:0005955 calcineurin complex(GO:0005955)
0.8 3.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.8 3.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.8 37.2 GO:0048786 presynaptic active zone(GO:0048786)
0.7 2.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.7 9.0 GO:0031209 SCAR complex(GO:0031209)
0.7 4.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.7 7.3 GO:0031045 dense core granule(GO:0031045)
0.6 1.9 GO:0000806 Y chromosome(GO:0000806)
0.6 3.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.6 7.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.5 2.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.5 28.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.5 3.5 GO:0036021 endolysosome lumen(GO:0036021)
0.5 6.9 GO:0035102 PRC1 complex(GO:0035102)
0.5 12.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 14.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.4 37.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 69.2 GO:0030426 growth cone(GO:0030426)
0.4 5.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.4 7.7 GO:0005922 connexon complex(GO:0005922)
0.4 9.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.4 12.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 3.9 GO:0045180 basal cortex(GO:0045180)
0.3 9.8 GO:0032420 stereocilium(GO:0032420)
0.3 4.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 28.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 9.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 1.9 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.3 12.2 GO:0031904 endosome lumen(GO:0031904)
0.3 4.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 15.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 18.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 4.0 GO:0017119 Golgi transport complex(GO:0017119)
0.3 14.4 GO:0031519 PcG protein complex(GO:0031519)
0.3 15.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.3 5.8 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.3 41.2 GO:0055037 recycling endosome(GO:0055037)
0.2 6.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 3.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 4.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 5.3 GO:0043198 dendritic shaft(GO:0043198)
0.2 21.8 GO:0031514 motile cilium(GO:0031514)
0.2 7.8 GO:0097542 ciliary tip(GO:0097542)
0.2 18.7 GO:0005814 centriole(GO:0005814)
0.2 15.7 GO:0008021 synaptic vesicle(GO:0008021)
0.2 7.4 GO:0042734 presynaptic membrane(GO:0042734)
0.2 2.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 4.4 GO:0034451 centriolar satellite(GO:0034451)
0.2 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 3.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 21.6 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.2 GO:0005577 fibrinogen complex(GO:0005577)
0.2 12.9 GO:0016459 myosin complex(GO:0016459)
0.2 3.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 37.4 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 7.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 10.6 GO:0098793 presynapse(GO:0098793)
0.1 0.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 4.6 GO:0044306 neuron projection terminus(GO:0044306)
0.1 1.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 8.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 7.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 3.7 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 5.2 GO:0043204 perikaryon(GO:0043204)
0.1 2.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 4.6 GO:0042641 actomyosin(GO:0042641)
0.1 3.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.9 GO:0030904 retromer complex(GO:0030904)
0.1 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 5.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.0 GO:0005604 basement membrane(GO:0005604)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 1.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 6.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.7 GO:0031091 platelet alpha granule(GO:0031091)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 9.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 19.7 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 30.7 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
6.9 41.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
4.2 12.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
3.5 10.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
3.4 17.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
2.4 24.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
2.4 16.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.4 7.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
2.2 19.6 GO:0032051 clathrin light chain binding(GO:0032051)
2.2 8.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
2.1 10.3 GO:0052841 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
2.0 6.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.9 14.9 GO:0004565 beta-galactosidase activity(GO:0004565)
1.8 14.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.8 8.9 GO:0016403 dimethylargininase activity(GO:0016403)
1.8 19.5 GO:0008430 selenium binding(GO:0008430)
1.7 6.7 GO:0008431 vitamin E binding(GO:0008431)
1.5 4.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.5 4.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
1.5 10.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.5 16.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.4 4.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.4 4.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.4 4.2 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
1.4 6.9 GO:0010465 nerve growth factor receptor activity(GO:0010465)
1.3 4.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.3 5.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
1.3 27.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.3 11.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.3 11.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.2 6.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
1.2 7.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.2 28.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.1 14.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
1.1 11.2 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
1.1 7.7 GO:0017002 activin-activated receptor activity(GO:0017002)
1.1 18.7 GO:0003688 DNA replication origin binding(GO:0003688)
1.1 4.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.1 17.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.1 3.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.0 3.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.9 21.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.9 5.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.9 9.7 GO:0019211 phosphatase activator activity(GO:0019211)
0.9 6.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.8 26.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.8 5.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.8 3.3 GO:0035473 lipase binding(GO:0035473)
0.8 15.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.8 13.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.7 4.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.7 2.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 7.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 2.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.7 9.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.7 11.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.7 17.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.7 7.5 GO:0030274 LIM domain binding(GO:0030274)
0.7 13.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.7 7.9 GO:0019534 toxin transporter activity(GO:0019534)
0.6 1.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.6 11.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 6.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.6 14.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.6 12.4 GO:0017091 AU-rich element binding(GO:0017091)
0.6 20.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.6 3.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 7.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 4.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.5 1.6 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.5 2.1 GO:0035276 ethanol binding(GO:0035276)
0.5 7.7 GO:0005243 gap junction channel activity(GO:0005243)
0.5 2.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.5 17.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.5 7.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.5 1.0 GO:0008252 nucleotidase activity(GO:0008252)
0.4 4.0 GO:0048495 Roundabout binding(GO:0048495)
0.4 3.1 GO:0043559 insulin binding(GO:0043559)
0.4 44.5 GO:0005262 calcium channel activity(GO:0005262)
0.4 4.3 GO:0046625 sphingolipid binding(GO:0046625)
0.4 9.7 GO:0030552 cAMP binding(GO:0030552)
0.4 13.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.4 10.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.4 3.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 2.8 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.4 5.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.4 12.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.4 1.4 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.4 2.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.4 2.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 15.3 GO:0070412 R-SMAD binding(GO:0070412)
0.3 2.8 GO:0043426 MRF binding(GO:0043426)
0.3 9.6 GO:0043394 proteoglycan binding(GO:0043394)
0.3 3.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 6.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.3 1.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.3 1.4 GO:0070905 serine binding(GO:0070905)
0.3 7.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 13.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 11.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 1.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 23.6 GO:0030165 PDZ domain binding(GO:0030165)
0.3 4.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 3.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.3 5.5 GO:0031489 myosin V binding(GO:0031489)
0.2 3.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 6.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 3.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 6.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.9 GO:0043422 protein kinase B binding(GO:0043422)
0.2 2.0 GO:0042731 PH domain binding(GO:0042731)
0.2 6.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 11.0 GO:0017022 myosin binding(GO:0017022)
0.2 16.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 2.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 5.7 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.4 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.2 8.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.2 3.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 9.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 2.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 2.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 0.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 1.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 2.8 GO:0005522 profilin binding(GO:0005522)
0.2 3.1 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 9.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.9 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 13.7 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 1.3 GO:0001948 glycoprotein binding(GO:0001948)
0.1 1.0 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 15.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 18.6 GO:0044325 ion channel binding(GO:0044325)
0.1 17.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 12.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0015111 iodide transmembrane transporter activity(GO:0015111) oxalate transmembrane transporter activity(GO:0019531)
0.1 11.8 GO:0019902 phosphatase binding(GO:0019902)
0.1 1.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 2.7 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.9 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 4.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 2.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 6.3 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 4.3 GO:0015297 antiporter activity(GO:0015297)
0.1 2.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 10.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 7.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 7.1 GO:0003774 motor activity(GO:0003774)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 4.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 35.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 3.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.0 6.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.8 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 2.0 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 3.3 GO:0008083 growth factor activity(GO:0008083)
0.0 6.9 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.6 25.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.6 7.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.6 32.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.5 7.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.5 8.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.4 13.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.4 6.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 24.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.3 12.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 10.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 11.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 14.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 8.6 PID TNF PATHWAY TNF receptor signaling pathway
0.3 13.2 PID AURORA A PATHWAY Aurora A signaling
0.3 6.0 PID BCR 5PATHWAY BCR signaling pathway
0.2 4.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 18.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 9.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 3.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 12.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 11.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 6.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 7.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 24.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 11.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 6.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 6.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 4.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 19.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 3.2 PID ALK1 PATHWAY ALK1 signaling events
0.1 6.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.3 PID AURORA B PATHWAY Aurora B signaling
0.1 6.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 4.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 15.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 2.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 5.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 12.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.0 13.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.9 30.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.8 19.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.8 20.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.8 15.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.7 28.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6 19.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.6 18.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.5 14.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.5 5.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 21.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.5 9.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.5 14.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.5 11.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.4 7.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 15.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 5.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.4 5.9 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.4 17.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.4 6.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 17.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 11.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 3.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 15.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 10.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 1.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 2.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 16.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 8.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 9.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 16.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 3.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 4.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 4.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 1.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.2 7.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 2.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 2.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 2.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 12.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 2.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 4.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 3.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 5.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 3.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 4.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.8 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 1.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.9 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.1 1.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 17.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.3 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 3.7 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 10.2 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins