Project

averaged GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for VAX1_GSX2

Z-value: 0.65

Motif logo

logo of logo of

Transcription factors associated with VAX1_GSX2

Gene Symbol Gene ID Gene Info
VAX1
ENSG00000148704.8 ventral anterior homeobox 1
GSX2
ENSG00000180613.6 GS homeobox 2

Activity profile of VAX1_GSX2 motif

Sorted Z-values of VAX1_GSX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_111718036 8.54 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_111717600 8.47 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111717511 8.26 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr3_+_111718173 7.95 ENST00000494932.1
TAGLN3
transgelin 3
chr7_+_100770328 6.96 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr9_+_125132803 6.28 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_-_129062093 4.37 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr10_-_5046042 3.30 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr15_+_84115868 2.85 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr18_+_46065393 2.82 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr10_+_5005598 2.79 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr5_+_135394840 2.74 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr16_+_6069072 2.63 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_86253888 2.60 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr1_+_192778161 2.52 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr15_-_37393406 2.37 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr1_-_68698197 2.35 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr4_+_88896819 2.21 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr8_-_86290333 2.18 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr9_+_125133315 1.98 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_-_110501200 1.91 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1
WAS protein family, member 1
chr1_-_190446759 1.81 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr15_+_62853562 1.76 ENST00000561311.1
TLN2
talin 2
chr11_-_128894053 1.75 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chrX_-_18690210 1.75 ENST00000379984.3
RS1
retinoschisin 1
chr7_-_81399438 1.74 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_-_44588624 1.71 ENST00000438314.1
ENST00000409936.1
PREPL
prolyl endopeptidase-like
chr9_-_5339873 1.70 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr17_-_73663245 1.65 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chrX_-_13835147 1.64 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr22_-_18923655 1.64 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
PRODH
proline dehydrogenase (oxidase) 1
chr3_+_149191723 1.60 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr14_+_104182061 1.59 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr2_+_210517895 1.56 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr3_+_157154578 1.56 ENST00000295927.3
PTX3
pentraxin 3, long
chr14_+_104182105 1.56 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr2_+_234545148 1.55 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr1_+_62439037 1.55 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr4_-_87281196 1.54 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr2_-_44588694 1.50 ENST00000409957.1
PREPL
prolyl endopeptidase-like
chr12_+_15699286 1.46 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr2_-_73520667 1.45 ENST00000545030.1
ENST00000436467.2
EGR4
early growth response 4
chr19_+_45417921 1.44 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr2_-_44588679 1.44 ENST00000409411.1
PREPL
prolyl endopeptidase-like
chr22_-_39637135 1.41 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr4_-_87281224 1.40 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr22_-_39636914 1.40 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr1_-_68698222 1.35 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr2_-_188419078 1.34 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_7655329 1.34 ENST00000541972.1
CD163
CD163 molecule
chr4_-_169239921 1.32 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr19_-_58951496 1.29 ENST00000254166.3
ZNF132
zinc finger protein 132
chr12_+_66582919 1.28 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr10_+_96443378 1.26 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr12_+_26348246 1.22 ENST00000422622.2
SSPN
sarcospan
chr2_+_234580525 1.21 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr17_-_45266542 1.20 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27
cell division cycle 27
chr11_-_27722021 1.19 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr1_-_109618566 1.18 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr11_-_33913708 1.16 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr7_+_156433573 1.16 ENST00000311822.8
RNF32
ring finger protein 32
chr19_-_19302931 1.15 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr11_+_46958248 1.15 ENST00000536126.1
ENST00000278460.7
ENST00000378618.2
ENST00000395460.2
ENST00000378615.3
ENST00000543718.1
C11orf49
chromosome 11 open reading frame 49
chr14_-_104181771 1.14 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr2_-_166930131 1.13 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr12_-_10282742 1.13 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr4_+_41614909 1.12 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr7_-_81399329 1.12 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_32798547 1.11 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr5_+_66300446 1.10 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_+_234580499 1.10 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr1_-_207226313 1.10 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr1_+_12834984 1.09 ENST00000357726.4
PRAMEF12
PRAME family member 12
chr2_-_50201327 1.06 ENST00000412315.1
NRXN1
neurexin 1
chr7_-_99717463 1.06 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr16_-_31085514 1.04 ENST00000300849.4
ZNF668
zinc finger protein 668
chr12_+_81110684 0.98 ENST00000228644.3
MYF5
myogenic factor 5
chr1_+_152974218 0.96 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
SPRR3
small proline-rich protein 3
chr11_+_121447469 0.96 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr11_+_59824060 0.96 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr16_-_66764119 0.95 ENST00000569320.1
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr17_-_7167279 0.94 ENST00000571932.2
CLDN7
claudin 7
chr12_-_10282836 0.91 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr17_-_73663168 0.89 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr3_+_152552685 0.88 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr1_+_207226574 0.84 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr1_+_101003687 0.83 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr2_-_208031943 0.83 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_+_7013897 0.82 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr8_+_9413410 0.81 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr11_+_24518723 0.81 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr11_+_59824127 0.81 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr19_+_50016610 0.81 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chrX_+_43515467 0.80 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr12_+_7014064 0.80 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr6_+_29429217 0.79 ENST00000396792.2
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr21_-_35899113 0.77 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr17_-_4938712 0.77 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr11_-_102709441 0.76 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr6_+_160542870 0.74 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr12_+_18414446 0.74 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr15_+_58702742 0.73 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr1_+_186369704 0.73 ENST00000574641.1
OCLM
oculomedin
chr14_+_32798462 0.69 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr7_-_81399355 0.69 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr22_-_36903069 0.68 ENST00000216187.6
ENST00000423980.1
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr6_+_28317685 0.68 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
ZKSCAN3
zinc finger with KRAB and SCAN domains 3
chr8_-_62602327 0.67 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr7_-_81399411 0.67 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_160542821 0.67 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr19_-_19887185 0.66 ENST00000590092.1
ENST00000589910.1
ENST00000589508.1
ENST00000586645.1
ENST00000586816.1
ENST00000588223.1
ENST00000586885.1
LINC00663
long intergenic non-protein coding RNA 663
chr3_-_101039402 0.66 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr5_-_55412774 0.66 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr17_-_64225508 0.65 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr14_+_95027772 0.64 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr3_-_151034734 0.64 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr22_-_36903101 0.62 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr2_+_102953608 0.61 ENST00000311734.2
ENST00000409584.1
IL1RL1
interleukin 1 receptor-like 1
chr12_-_112123524 0.61 ENST00000327551.6
BRAP
BRCA1 associated protein
chr16_+_72088376 0.60 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr2_-_3521518 0.59 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr5_-_20575959 0.58 ENST00000507958.1
CDH18
cadherin 18, type 2
chr21_-_43346790 0.57 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr2_+_44502597 0.57 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr17_-_66951474 0.56 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr7_-_99716952 0.56 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr5_-_143550159 0.55 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
YIPF5
Yip1 domain family, member 5
chr9_+_90112590 0.54 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr12_+_122688090 0.53 ENST00000324189.4
ENST00000546192.1
B3GNT4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chrX_+_37639264 0.53 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr11_-_36619771 0.53 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chr8_+_107738240 0.52 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr10_-_61900762 0.52 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_8873531 0.51 ENST00000400677.3
HMX1
H6 family homeobox 1
chr9_+_90112767 0.51 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr7_+_100860949 0.51 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr14_-_54423529 0.51 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr12_+_106751436 0.51 ENST00000228347.4
POLR3B
polymerase (RNA) III (DNA directed) polypeptide B
chr8_-_102803163 0.50 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr1_-_150669604 0.49 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr18_-_19997878 0.48 ENST00000391403.2
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr14_+_61654271 0.47 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr17_+_72427477 0.47 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr18_+_22040593 0.47 ENST00000256906.4
HRH4
histamine receptor H4
chr9_+_131062367 0.47 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr12_-_71031220 0.46 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr6_+_29079668 0.44 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr19_+_42055879 0.44 ENST00000407170.2
ENST00000601116.1
ENST00000595395.1
CEACAM21
AC006129.2
carcinoembryonic antigen-related cell adhesion molecule 21
AC006129.2
chr14_-_71609965 0.43 ENST00000602957.1
RP6-91H8.3
RP6-91H8.3
chr12_-_10978957 0.43 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr2_-_169887827 0.42 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr11_+_66276550 0.41 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr7_-_100860851 0.41 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chrX_+_78003204 0.38 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr12_-_57039739 0.38 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr16_-_1464688 0.38 ENST00000389221.4
ENST00000508903.2
ENST00000397462.1
ENST00000301712.5
UNKL
unkempt family zinc finger-like
chr4_+_70796784 0.37 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr1_+_117544366 0.37 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr2_+_234826016 0.36 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr3_+_50273625 0.36 ENST00000536647.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr5_-_139726181 0.35 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr9_-_5304432 0.35 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr6_-_87804815 0.33 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr1_-_67266939 0.33 ENST00000304526.2
INSL5
insulin-like 5
chr18_+_22040620 0.33 ENST00000426880.2
HRH4
histamine receptor H4
chr1_+_84630645 0.32 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_18430160 0.32 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr2_+_32288657 0.32 ENST00000345662.1
SPAST
spastin
chr12_-_6233828 0.31 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr8_+_75262612 0.31 ENST00000220822.7
GDAP1
ganglioside induced differentiation associated protein 1
chr18_-_67624160 0.30 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr3_-_99569821 0.29 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr12_+_29376673 0.29 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr4_+_144354644 0.29 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr12_+_29376592 0.29 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr7_-_14028488 0.28 ENST00000405358.4
ETV1
ets variant 1
chr13_-_46626847 0.28 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr6_+_110501621 0.27 ENST00000368930.1
ENST00000307731.1
CDC40
cell division cycle 40
chr17_-_2996290 0.27 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr16_+_31885079 0.26 ENST00000300870.10
ENST00000394846.3
ZNF267
zinc finger protein 267
chr3_+_186353756 0.26 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chrX_+_21958674 0.25 ENST00000404933.2
SMS
spermine synthase
chr15_+_89631381 0.25 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr15_-_65903407 0.24 ENST00000395644.4
ENST00000567744.1
ENST00000568573.1
ENST00000562830.1
ENST00000569491.1
ENST00000561769.1
VWA9
von Willebrand factor A domain containing 9
chr4_-_25865159 0.24 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr12_+_101988627 0.24 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr6_+_31895254 0.24 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr13_+_73632897 0.23 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chrY_+_24454970 0.23 ENST00000414629.2
ENST00000445779.2
RBMY1J
RNA binding motif protein, Y-linked, family 1, member J
chr8_-_42623747 0.23 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr11_+_33061543 0.22 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr11_-_33774944 0.21 ENST00000532057.1
ENST00000531080.1
FBXO3
F-box protein 3
chr12_+_26348429 0.21 ENST00000242729.2
SSPN
sarcospan
chr3_-_164796269 0.21 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr4_+_41614720 0.20 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr12_-_22063787 0.20 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_81771806 0.19 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chrX_+_107334895 0.19 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr12_+_20963632 0.19 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_-_102651343 0.19 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX1_GSX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.2 3.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.9 6.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.8 2.5 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.7 2.2 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.7 2.8 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.5 4.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.5 1.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 8.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 1.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.4 1.6 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.4 1.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.4 3.9 GO:0051552 flavone metabolic process(GO:0051552)
0.4 1.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.4 1.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.4 2.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 1.4 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.4 2.5 GO:0010519 negative regulation of phospholipase activity(GO:0010519) regulation of adrenergic receptor signaling pathway(GO:0071877)
0.3 1.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 1.0 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3 1.6 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.3 0.9 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.3 0.8 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.3 1.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 1.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 1.4 GO:0048241 epinephrine transport(GO:0048241)
0.2 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.8 GO:0061743 motor learning(GO:0061743)
0.2 0.6 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2 0.6 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 0.8 GO:0032218 riboflavin transport(GO:0032218)
0.2 1.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.5 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 0.5 GO:0072097 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.7 GO:0009642 response to light intensity(GO:0009642)
0.1 0.8 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.1 1.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.5 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.6 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.8 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 1.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.7 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.5 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 4.6 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 1.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0060369 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.6 GO:1990822 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.1 0.8 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 4.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.1 1.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.7 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 2.0 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.1 GO:0051795 positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.3 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0051697 protein delipidation(GO:0051697)
0.1 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.1 3.1 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 1.2 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.8 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 2.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.7 GO:0051642 centrosome localization(GO:0051642)
0.0 1.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 2.4 GO:0008542 visual learning(GO:0008542)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 2.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 34.8 GO:0007417 central nervous system development(GO:0007417)
0.0 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.6 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 2.5 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 1.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.6 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 6.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.1 GO:0051013 axonal transport of mitochondrion(GO:0019896) microtubule severing(GO:0051013)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 1.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 2.1 GO:0007565 female pregnancy(GO:0007565)
0.0 0.4 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0009266 response to temperature stimulus(GO:0009266) response to heat(GO:0009408)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 0.6 GO:0097183 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.2 1.0 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 33.3 GO:0043209 myelin sheath(GO:0043209)
0.1 3.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 14.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.7 GO:0043194 axon initial segment(GO:0043194)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.1 GO:0042627 chylomicron(GO:0042627)
0.1 1.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 7.4 GO:0043197 dendritic spine(GO:0043197)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 2.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.2 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 3.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.0 6.1 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.6 4.8 GO:0004064 arylesterase activity(GO:0004064)
0.5 3.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.5 2.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 2.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.4 1.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 1.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.4 1.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.4 1.4 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.3 3.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 2.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.2 0.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 4.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 0.8 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.6 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.8 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 1.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 35.2 GO:0051015 actin filament binding(GO:0051015)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 4.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 4.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.6 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 8.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.0 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 5.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 1.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 5.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.3 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 4.5 ST ADRENERGIC Adrenergic Pathway
0.1 2.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 6.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 5.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 4.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 7.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 10.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 2.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 2.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 5.3 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.3 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 3.0 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation